Yun Li - Publications

Affiliations: 
2018- Molecular Genetics University of Toronto, Toronto, ON, Canada 
Area:
Stem cells, Autism, Organoids

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang WX, Douglas TR, Zhang H, Bhattacharya A, Rothenbroker M, Tang W, Sun Y, Jia Z, Muffat J, Li Y, Chou LYT. Universal, label-free, single-molecule visualization of DNA origami nanodevices across biological samples using origamiFISH. Nature Nanotechnology. PMID 37500778 DOI: 10.1038/s41565-023-01449-5  0.657
2023 Ahmed M, Muffat J, Li Y. Understanding neural development and diseases using CRISPR screens in human pluripotent stem cell-derived cultures. Frontiers in Cell and Developmental Biology. 11: 1158373. PMID 37101616 DOI: 10.3389/fcell.2023.1158373  0.726
2021 Bhattacharya A, Choi WWY, Muffat J, Li Y. Modeling developmental brain diseases using human pluripotent stem cell-derived brain organoids - progress and perspective. Journal of Molecular Biology. 167386. PMID 34883115 DOI: 10.1016/j.jmb.2021.167386  0.714
2021 Dhaliwal N, Choi WWY, Muffat J, Li Y. Modeling PTEN overexpression-induced microcephaly in human brain organoids. Molecular Brain. 14: 131. PMID 34461955 DOI: 10.1186/s13041-021-00841-3  0.731
2020 Tian A, Muffat J, Li Y. Studying Human Neurodevelopment and Diseases Using 3D Brain Organoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 40: 1186-1193. PMID 32024767 DOI: 10.1523/Jneurosci.0519-19.2019  0.726
2019 Li Y, Muffat J, Omer Javed A, Keys HR, Lungjangwa T, Bosch I, Khan M, Virgilio MC, Gehrke L, Sabatini DM, Jaenisch R. Genome-wide CRISPR screen for Zika virus resistance in human neural cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019072 DOI: 10.1073/Pnas.1900867116  0.746
2018 Omer Javed A, Li Y, Muffat J, Su KC, Cohen MA, Lungjangwa T, Aubourg P, Cheeseman IM, Jaenisch R. Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Reports. 25: 368-382.e5. PMID 30304678 DOI: 10.1016/J.Celrep.2018.09.032  0.743
2018 Muffat J, Li Y, Omer A, Durbin A, Bosch I, Bakiasi G, Richards E, Meyer A, Gehrke L, Jaenisch R. Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915057 DOI: 10.1073/Pnas.1719266115  0.746
2018 Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, et al. Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors. Molecular Psychiatry. 23: 791. PMID 29565043 DOI: 10.1038/Mp.2018.5  0.552
2018 Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R. Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell. PMID 29456084 DOI: 10.1016/J.Cell.2018.01.012  0.756
2017 Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, et al. MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling. Molecular Psychiatry. PMID 28439102 DOI: 10.1038/Mp.2017.86  0.535
2016 Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R. Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. PMID 28041895 DOI: 10.1016/J.Stem.2016.11.017  0.747
2016 Muffat J, Li Y, Jaenisch R. CNS disease models with human pluripotent stem cells in the CRISPR age. Current Opinion in Cell Biology. 43: 96-103. PMID 27768957 DOI: 10.1016/J.Ceb.2016.10.001  0.762
2016 Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, Bakiasi G, Tsai LH, Aubourg P, Ransohoff RM, Jaenisch R. Efficient derivation of microglia-like cells from human pluripotent stem cells. Nature Medicine. PMID 27668937 DOI: 10.1038/Nm.4189  0.753
2015 Yu J, Wang L, Akinyi M, Li Y, Duan Z, Zhu Y, Fan G. Danshensu protects isolated heart against ischemia reperfusion injury through activation of Akt/ERK1/2/Nrf2 signaling. International Journal of Clinical and Experimental Medicine. 8: 14793-14804. PMID 26628961  0.372
2015 Zhang K, Wang Z, Fan GZ, Wang J, Gao S, Li Y, Sun L, Yin CC, Liu WJ. Two polar residues within C-terminal domain of M1 are critical for the formation of influenza A Virions. Cellular Microbiology. PMID 25939747 DOI: 10.1111/Cmi.12457  0.35
2015 Fan GL, Yao Y, Yao L, Li Y. PDCD5 transfection increases cisplatin sensitivity and decreases invasion in hepatic cancer cells. Oncology Letters. 9: 411-417. PMID 25436001 DOI: 10.3892/ol.2014.2645  0.424
2013 Li Y, Wang H, Muffat J, Cheng AW, Orlando DA, Lovén J, Kwok SM, Feldman DA, Bateup HS, Gao Q, Hockemeyer D, Mitalipova M, Lewis CA, Vander Heiden MG, Sur M, et al. Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. Cell Stem Cell. 13: 446-58. PMID 24094325 DOI: 10.1016/J.Stem.2013.09.001  0.778
2013 Huang H, Jiang X, Li Z, Li Y, Song CX, He C, Sun M, Chen P, Gurbuxani S, Wang J, Hong GM, Elkahloun AG, Arnovitz S, Wang J, Szulwach K, et al. TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 11994-9. PMID 23818607 DOI: 10.1073/Pnas.1310656110  0.403
2013 Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, et al. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 152: 1077-90. PMID 23434321 DOI: 10.1016/J.Cell.2013.01.053  0.465
2012 Li Y, Yui D, Luikart BW, McKay RM, Li Y, Rubenstein JL, Parada LF. Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development. Proceedings of the National Academy of Sciences of the United States of America. 109: 15491-6. PMID 22949667 DOI: 10.1073/Pnas.1212899109  0.738
2012 Chen J, Li Y, Yu TS, McKay RM, Burns DK, Kernie SG, Parada LF. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature. 488: 522-6. PMID 22854781 DOI: 10.1038/Nature11287  0.475
2012 Sanchez-Ortiz E, Yui D, Song D, Li Y, Rubenstein JL, Reichardt LF, Parada LF. TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4065-79. PMID 22442072 DOI: 10.1523/Jneurosci.6314-11.2012  0.532
2012 Li Y, Li Y, McKay RM, Riethmacher D, Parada LF. Neurofibromin modulates adult hippocampal neurogenesis and behavioral effects of antidepressants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3529-39. PMID 22399775 DOI: 10.1523/Jneurosci.3469-11.2012  0.537
2011 Luikart BW, Bensen AL, Washburn EK, Perederiy JV, Su KG, Li Y, Kernie SG, Parada LF, Westbrook GL. miR-132 mediates the integration of newborn neurons into the adult dentate gyrus. Plos One. 6: e19077. PMID 21611182 DOI: 10.1371/Journal.Pone.0019077  0.716
2009 Choi SH, Li Y, Parada LF, Sisodia SS. Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF. Molecular Neurodegeneration. 4: 52. PMID 20025751 DOI: 10.1186/1750-1326-4-52  0.555
2009 Chen J, Kwon CH, Lin L, Li Y, Parada LF. Inducible site-specific recombination in neural stem/progenitor cells. Genesis (New York, N.Y. : 2000). 47: 122-31. PMID 19117051 DOI: 10.1002/Dvg.20465  0.516
2009 Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell. 15: 45-56. PMID 19111880 DOI: 10.1016/J.Ccr.2008.12.006  0.505
2008 Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, et al. Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell. 135: 437-48. PMID 18984156 DOI: 10.1016/J.Cell.2008.08.041  0.443
2008 Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron. 59: 399-412. PMID 18701066 DOI: 10.1016/J.Neuron.2008.06.023  0.732
2008 Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF. Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Research. 68: 3286-94. PMID 18451155 DOI: 10.1158/0008-5472.Can-07-6867  0.483
2008 Lush ME, Li Y, Kwon CH, Chen J, Parada LF. Neurofibromin is required for barrel formation in the mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1580-7. PMID 18272679 DOI: 10.1523/Jneurosci.5236-07.2008  0.551
2008 Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment (DOI:10.1016/j.neuron.2008.06.023) Neuron. 60: 730. DOI: 10.1016/J.Neuron.2008.10.021  0.723
2006 Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, Li Y, Baker SJ, Parada LF. Pten regulates neuronal arborization and social interaction in mice. Neuron. 50: 377-88. PMID 16675393 DOI: 10.1016/J.Neuron.2006.03.023  0.73
2006 Kwon CH, Zhou J, Li Y, Kim KW, Hensley LL, Baker SJ, Parada LF. Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis (New York, N.Y. : 2000). 44: 130-5. PMID 16496331 DOI: 10.1002/Gene.20197  0.511
1992 Holtzman DM, Li Y, Parada LF, Kinsman S, Chen CK, Valletta JS, Zhou J, Long JB, Mobley WC. p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF. Neuron. 9: 465-78. PMID 1524827 DOI: 10.1016/0896-6273(92)90184-F  0.489
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