Luis Parada, Ph.D. - Publications

University of Texas Southwestern Medical Center, Dallas, TX, United States 
Developmental Biology

202 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sun D, Xie XP, Zhang X, Wang Z, Sait SF, Iyer SV, Chen YJ, Brown R, Laks DR, Chipman ME, Shern JF, Parada LF. Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression. Cell Stem Cell. PMID 34010628 DOI: 10.1016/j.stem.2021.04.029  0.84
2021 Qin Y, Wong B, Zhong L, Geng F, Parada LF, Wen D. Generation of Sex-Reversed Female Clonal Mice via CRISPR-Cas9-Mediated Y Chromosome Deletion in Male Embryonic Stem Cells. The Crispr Journal. PMID 33567216 DOI: 10.1089/crispr.2020.0074  0.48
2020 Xie XP, Laks DR, Sun D, Poran A, Laughney AM, Wang Z, Sam J, Belenguer G, Fariñas I, Elemento O, Zhou X, Parada LF. High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging. Proceedings of the National Academy of Sciences of the United States of America. PMID 33229571 DOI: 10.1073/pnas.2014389117  0.84
2020 Wang Z, Sun D, Chen YJ, Xie X, Shi Y, Tabar V, Brennan CW, Bale TA, Jayewickreme CD, Laks DR, Alcantara Llaguno S, Parada LF. Cell Lineage-Based Stratification for Glioblastoma. Cancer Cell. PMID 32649888 DOI: 10.1016/J.Ccell.2020.06.003  0.96
2020 Sait SF, Tang K, Brown R, Sun D, Xie X, Neel B, Parada L. Abstract 1889: Allosteric inhibition of SHP2 prevents adaptive resistance to MEK inhibition in neurofibromatosis type 1 associated malignant peripheral nerve sheath tumors Cancer Research. 80: 1889-1889. DOI: 10.1158/1538-7445.Am2020-1889  0.96
2019 Bagrow JP, Liu X, Mitchell L. Publisher Correction: Information flow reveals prediction limits in online social activity. Nature Human Behaviour. 3: 195. PMID 30944454 DOI: 10.1038/S41562-019-0547-0  0.36
2019 Rauen KA, Alsaegh A, Ben-Shachar S, Berman Y, Blakeley J, Cordeiro I, Elgersma Y, Evans DG, Fisher MJ, Frayling IM, George J, Huson SM, Kerr B, Khire U, Korf B, ... ... Parada LF, et al. First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and advances of new therapeutics. American Journal of Medical Genetics. Part A. PMID 30908877 DOI: 10.1002/Ajmg.A.61125  0.32
2019 Shi Y, Lim SK, Liang Q, Iyer SV, Wang HY, Wang Z, Xie X, Sun D, Chen YJ, Tabar V, Gutin P, Williams N, De Brabander JK, Parada LF. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. PMID 30842654 DOI: 10.1038/S41586-019-0993-X  0.96
2019 Llaguno SA, Sun D, Pedraza AM, Vera E, Wang Z, Burns DK, Parada LF. Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction. Nature Neuroscience. PMID 30778149 DOI: 10.1038/S41593-018-0333-8  0.84
2018 Sun D, Parada L. Abstract B14: A restricted cell population propagates MPNST growth after treatment Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-B14  0.68
2017 Ma Z, Zang T, Birnbaum SG, Wang Z, Johnson JE, Zhang CL, Parada LF. TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response. Nature Communications. 8: 1668. PMID 29162814 DOI: 10.1038/S41467-017-01709-8  0.84
2016 Alcantara Llaguno SR, Xie X, Parada LF. Cell of Origin and Cancer Stem Cells in Tumor Suppressor Mouse Models of Glioblastoma. Cold Spring Harbor Symposia On Quantitative Biology. PMID 27815542 DOI: 10.1101/sqb.2016.81.030973  0.96
2015 Alcantara Llaguno SR, Wang Z, Sun D, Chen J, Xu J, Kim E, Hatanpaa KJ, Raisanen JM, Burns DK, Johnson JE, Parada LF. Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes. Cancer Cell. 28: 429-40. PMID 26461091 DOI: 10.1016/J.Ccell.2015.09.007  1
2015 Lubeck BA, Lapinski PE, Oliver JA, Ksionda O, Parada LF, Zhu Y, Maillard I, Chiang M, Roose J, King PD. Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia. Journal of Immunology (Baltimore, Md. : 1950). 195: 31-5. PMID 26002977 DOI: 10.4049/Jimmunol.1402639  1
2015 Zong H, Parada LF, Baker SJ. Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harbor Perspectives in Biology. 7. PMID 25635044 DOI: 10.1101/Cshperspect.A020610  1
2015 Penzo MA, Robert V, Tucciarone J, De Bundel D, Wang M, Van Aelst L, Darvas M, Parada LF, Palmiter RD, He M, Huang ZJ, Li B. The paraventricular thalamus controls a central amygdala fear circuit. Nature. 519: 455-9. PMID 25600269 DOI: 10.1038/Nature13978  1
2015 Rauen KA, Huson SM, Burkitt-Wright E, Evans DG, Farschtschi S, Ferner RE, Gutmann DH, Hanemann CO, Kerr B, Legius E, Parada LF, Patton M, Peltonen J, Ratner N, Riccardi VM, et al. Recent developments in neurofibromatoses and RASopathies: management, diagnosis and current and future therapeutic avenues. American Journal of Medical Genetics. Part A. 167: 1-10. PMID 25393061 DOI: 10.1002/Ajmg.A.36793  1
2015 Kwon CH, Burns DK, Parada LF. Brain tumors Molecular Oncology: Causes of Cancer and Targets For Treatment. 641-651. DOI: 10.1017/CBO9781139046947.058  1
2015 He D, Wang Z, Parada L. MINED: An efficient mutual information based epistasis detection method to improve quantitative genetic trait prediction Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9096: 108-124. DOI: 10.1007/978-3-319-19048-8_10  0.84
2014 Sanchez-Ortiz E, Cho W, Nazarenko I, Mo W, Chen J, Parada LF. NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development. Genes & Development. 28: 2407-20. PMID 25367036 DOI: 10.1101/gad.246603.114  1
2014 Shi Y, Lim SK, Parada LF. The soft underbelly of tumor cells. Cell Research. 24: 910-1. PMID 24874955 DOI: 10.1038/cr.2014.72  1
2014 Anastasia A, Deinhardt K, Wang S, Martin L, Nichol D, Irmady K, Trinh J, Parada L, Rafii S, Hempstead BL, Kermani P. Trkb signaling in pericytes is required for cardiac microvessel stabilization. Plos One. 9: e87406. PMID 24498100 DOI: 10.1371/Journal.Pone.0087406  1
2014 Amiri A, Sanchez-Ortiz E, Cho W, Birnbaum SG, Xu J, McKay RM, Parada LF. Analysis of FMR1 deletion in a subpopulation of post-mitotic neurons in mouse cortex and hippocampus. Autism Research : Official Journal of the International Society For Autism Research. 7: 60-71. PMID 24408886 DOI: 10.1002/aur.1342  1
2014 Chau V, Lim SK, Mo W, Liu C, Patel AJ, McKay RM, Wei S, Posner BA, De Brabander JK, Williams NS, Parada LF, Le LQ. Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors. Cancer Research. 74: 586-97. PMID 24285727 DOI: 10.1158/0008-5472.Can-13-1934  1
2014 Haws ME, Jaramillo TC, Espinosa F, Widman AJ, Stuber GD, Sparta DR, Tye KM, Russo SJ, Parada LF, Stavarache M, Kaplitt M, Bonci A, Powell CM. PTEN knockdown alters dendritic spine/protrusion morphology, not density. The Journal of Comparative Neurology. 522: 1171-90. PMID 24264880 DOI: 10.1002/Cne.23488  1
2013 Ribeiro S, Napoli I, White IJ, Parrinello S, Flanagan AM, Suter U, Parada LF, Lloyd AC. Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve. Cell Reports. 5: 126-36. PMID 24075988 DOI: 10.1016/J.Celrep.2013.08.033  1
2013 Nalepa G, Barnholtz-Sloan J, Enzor R, Dey D, He Y, Gehlhausen JR, Lehmann AS, Park SJ, Yang Y, Yang X, Chen S, Guan X, Chen Y, Renbarger J, Yang FC, ... Parada LF, et al. The tumor suppressor CDKN3 controls mitosis. The Journal of Cell Biology. 201: 997-1012. PMID 23775190 DOI: 10.1083/Jcb.201205125  1
2013 Biddlestone-Thorpe L, Sajjad M, Rosenberg E, Beckta JM, Valerie NC, Tokarz M, Adams BR, Wagner AF, Khalil A, Gilfor D, Golding SE, Deb S, Temesi DG, Lau A, O'Connor MJ, ... ... Parada LF, et al. ATM kinase inhibition preferentially sensitizes p53-mutant glioma to ionizing radiation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3189-200. PMID 23620409 DOI: 10.1158/1078-0432.Ccr-12-3408  1
2013 Oliver JA, Lapinski PE, Lubeck BA, Turner JS, Parada LF, Zhu Y, King PD. The Ras GTPase-activating protein neurofibromin 1 promotes the positive selection of thymocytes. Molecular Immunology. 55: 292-302. PMID 23522726 DOI: 10.1016/j.molimm.2013.03.005  1
2013 Mason BL, Lobo MK, Parada LF, Lutter M. Trk B signaling in dopamine 1 receptor neurons regulates food intake and body weight. Obesity (Silver Spring, Md.). 21: 2372-6. PMID 23512795 DOI: 10.1002/oby.20382  1
2013 Takeuchi K, Gertner MJ, Zhou J, Parada LF, Bennett MV, Zukin RS. Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism. Proceedings of the National Academy of Sciences of the United States of America. 110: 4738-43. PMID 23487788 DOI: 10.1073/pnas.1222803110  1
2013 Wang Y, Lin L, Lai H, Parada LF, Lei L. Transcription factor Sox11 is essential for both embryonic and adult neurogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 638-53. PMID 23483698 DOI: 10.1002/Dvdy.23962  1
2013 Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, ... Parada LF, et al. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 152: 1077-90. PMID 23434321 DOI: 10.1016/J.Cell.2013.01.053  1
2013 Acosta MT, Bearden CE, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, Silva AJ. Corrigendum to "The Learning Disabilities Network (LeaDNet): Using Neurofibromatosis Type 1 [NF1] as a Paradigm for Translational Research" American Journal of Medical Genetics, Part A. 161: 236. DOI: 10.1002/Ajmg.A.35667  1
2012 Robertson KA, Nalepa G, Yang FC, Bowers DC, Ho CY, Hutchins GD, Croop JM, Vik TA, Denne SC, Parada LF, Hingtgen CM, Walsh LE, Yu M, Pradhan KR, Edwards-Brown MK, et al. Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial. The Lancet. Oncology. 13: 1218-24. PMID 23099009 DOI: 10.1016/S1470-2045(12)70414-X  1
2012 Gutmann DH, Parada LF, Silva AJ, Ratner N. Neurofibromatosis type 1: modeling CNS dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14087-93. PMID 23055477 DOI: 10.1523/Jneurosci.3242-12.2012  1
2012 Li Y, Yui D, Luikart BW, McKay RM, Li Y, Rubenstein JL, Parada LF. Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development. Proceedings of the National Academy of Sciences of the United States of America. 109: 15491-6. PMID 22949667 DOI: 10.1073/Pnas.1212899109  1
2012 Kim TH, Song J, Alcantara Llaguno SR, Murnan E, Liyanarachchi S, Palanichamy K, Yi JY, Viapiano MS, Nakano I, Yoon SO, Wu H, Parada LF, Kwon CH. Suppression of peroxiredoxin 4 in glioblastoma cells increases apoptosis and reduces tumor growth. Plos One. 7: e42818. PMID 22916164 DOI: 10.1371/Journal.Pone.0042818  1
2012 Chen J, Li Y, Yu TS, McKay RM, Burns DK, Kernie SG, Parada LF. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature. 488: 522-6. PMID 22854781 DOI: 10.1038/Nature11287  1
2012 Acosta MT, Bearden CE, Castellanos FX, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, et al. The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research. American Journal of Medical Genetics. Part A. 158: 2225-32. PMID 22821737 DOI: 10.1002/Ajmg.A.35535  1
2012 Zhou J, Parada LF. PTEN signaling in autism spectrum disorders. Current Opinion in Neurobiology. 22: 873-9. PMID 22664040 DOI: 10.1016/j.conb.2012.05.004  1
2012 Amiri A, Cho W, Zhou J, Birnbaum SG, Sinton CM, McKay RM, Parada LF. Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5880-90. PMID 22539849 DOI: 10.1523/JNEUROSCI.5462-11.2012  1
2012 Borrego-Diaz E, Terai K, Lialyte K, Wise AL, Esfandyari T, Behbod F, Mautner VF, Spyra M, Taylor S, Parada LF, Upadhyaya M, Farassati F. Overactivation of Ras signaling pathway in CD133+ MPNST cells. Journal of Neuro-Oncology. 108: 423-34. PMID 22484909 DOI: 10.1007/S11060-012-0852-1  1
2012 Chen J, McKay RM, Parada LF. Malignant glioma: lessons from genomics, mouse models, and stem cells. Cell. 149: 36-47. PMID 22464322 DOI: 10.1016/j.cell.2012.03.009  1
2012 Sanchez-Ortiz E, Yui D, Song D, Li Y, Rubenstein JL, Reichardt LF, Parada LF. TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4065-79. PMID 22442072 DOI: 10.1523/Jneurosci.6314-11.2012  1
2012 Li Y, Li Y, McKay RM, Riethmacher D, Parada LF. Neurofibromin modulates adult hippocampal neurogenesis and behavioral effects of antidepressants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3529-39. PMID 22399775 DOI: 10.1523/Jneurosci.3469-11.2012  1
2012 Colombo E, Cordiglieri C, Melli G, Newcombe J, Krumbholz M, Parada LF, Medico E, Hohlfeld R, Meinl E, Farina C. Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration. The Journal of Experimental Medicine. 209: 521-35. PMID 22393127 DOI: 10.1084/Jem.20110698  1
2012 Alanne MH, Siljamäki E, Peltonen S, Väänänen K, Windle JJ, Parada LF, Määttä JA, Peltonen J. Phenotypic characterization of transgenic mice harboring Nf1+/- or Nf1-/- osteoclasts in otherwise Nf1+/+ background. Journal of Cellular Biochemistry. 113: 2136-46. PMID 22307743 DOI: 10.1002/Jcb.24088  1
2012 Fassl A, Tagscherer KE, Richter J, Berriel Diaz M, Alcantara Llaguno SR, Campos B, Kopitz J, Herold-Mende C, Herzig S, Schmidt MH, Parada LF, Wiestler OD, Roth W. Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1. Oncogene. 31: 4698-708. PMID 22249262 DOI: 10.1038/onc.2011.615  1
2012 Parada LF. Neurofibromatosis type 1: Future directions (where do we go from here?) Neurofibromatosis Type 1: Molecular and Cellular Biology. 2147483647: 691-698. DOI: 10.1007/978-3-642-32864-0_44  1
2012 Buchstaller J, Clapp DW, Parada LF, Zhu Y. Cell of origin and the contribution of microenvironment in NF1 tumorigenesis and therapeutic implications Neurofibromatosis Type 1: Molecular and Cellular Biology. 2147483647: 549-568. DOI: 10.1007/978-3-642-32864-0_36  1
2011 Zhou J, Shrikhande G, Xu J, McKay RM, Burns DK, Johnson JE, Parada LF. Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle. Genes & Development. 25: 1595-600. PMID 21828270 DOI: 10.1101/Gad.16750211  1
2011 Luikart BW, Bensen AL, Washburn EK, Perederiy JV, Su KG, Li Y, Kernie SG, Parada LF, Westbrook GL. miR-132 mediates the integration of newborn neurons into the adult dentate gyrus. Plos One. 6: e19077. PMID 21611182 DOI: 10.1371/Journal.Pone.0019077  1
2011 Le LQ, Liu C, Shipman T, Chen Z, Suter U, Parada LF. Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development. Cancer Research. 71: 4686-95. PMID 21551250 DOI: 10.1158/0008-5472.Can-10-4577  1
2011 Blaiss CA, Yu TS, Zhang G, Chen J, Dimchev G, Parada LF, Powell CM, Kernie SG. Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4906-16. PMID 21451029 DOI: 10.1523/Jneurosci.5265-10.2011  1
2011 Lim SK, Llaguno SR, McKay RM, Parada LF. Glioblastoma multiforme: a perspective on recent findings in human cancer and mouse models. Bmb Reports. 44: 158-64. PMID 21429292 DOI: 10.5483/BMBRep.2011.44.3.158  1
2011 Hambardzumyan D, Parada LF, Holland EC, Charest A. Genetic modeling of gliomas in mice: new tools to tackle old problems. Glia. 59: 1155-68. PMID 21305617 DOI: 10.1002/glia.21142  1
2011 Harada C, Guo X, Namekata K, Kimura A, Nakamura K, Tanaka K, Parada LF, Harada T. Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration. Nature Communications. 2: 189. PMID 21304518 DOI: 10.1038/ncomms1190  1
2011 Alcantara Llaguno SR, Chen Y, McKay RM, Parada LF. Stem cells in brain tumor development. Current Topics in Developmental Biology. 94: 15-44. PMID 21295683 DOI: 10.1016/B978-0-12-380916-2.00002-4  1
2011 Huson SM, Acosta MT, Belzberg AJ, Bernards A, Chernoff J, Cichowski K, Gareth Evans D, Ferner RE, Giovannini M, Korf BR, Listernick R, North KN, Packer RJ, Parada LF, Peltonen J, et al. Back to the future: proceedings from the 2010 NF Conference. American Journal of Medical Genetics. Part A. 155: 307-21. PMID 21271647 DOI: 10.1002/Ajmg.A.33804  1
2010 Namekata K, Harada C, Taya C, Guo X, Kimura H, Parada LF, Harada T. Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex. Proceedings of the National Academy of Sciences of the United States of America. 107: 7586-91. PMID 20368433 DOI: 10.1073/pnas.0914514107  1
2010 Parada LM, Liang X. A novel approach to infer streamflow signals for ungauged basins Advances in Water Resources. 33: 372-386. DOI: 10.1016/J.Advwatres.2010.01.003  0.72
2010 Le LQ, Shipman T, Burns DK, Parada LF. Stem cell origin and microenvironment contribution for NF1-associated neurofibromas Ifmbe Proceedings. 27: 219-222. DOI: 10.1007/978-3-642-12020-6-55  1
2009 Choi SH, Li Y, Parada LF, Sisodia SS. Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF. Molecular Neurodegeneration. 4: 52. PMID 20025751 DOI: 10.1186/1750-1326-4-52  1
2009 Alcantara Llaguno SR, Chen J, Parada LF. Signaling in malignant astrocytomas: role of neural stem cells and its therapeutic implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 7124-9. PMID 19934302 DOI: 10.1158/1078-0432.CCR-09-0433  1
2009 Pitetti JL, Torre D, Conne B, Papaioannou MD, Cederroth CR, Xuan S, Kahn R, Parada LF, Vassalli JD, Efstratiadis A, Nef S. Insulin receptor and IGF1R are not required for oocyte growth, differentiation, and maturation in mice. Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation. 3: 264-72. PMID 19851056 DOI: 10.1159/000252813  1
2009 Gregorian C, Nakashima J, Dry SM, Nghiemphu PL, Smith KB, Ao Y, Dang J, Lawson G, Mellinghoff IK, Mischel PS, Phelps M, Parada LF, Liu X, Sofroniew MV, Eilber FC, et al. PTEN dosage is essential for neurofibroma development and malignant transformation. Proceedings of the National Academy of Sciences of the United States of America. 106: 19479-84. PMID 19846776 DOI: 10.1073/Pnas.0910398106  1
2009 Zhou J, Parada LF. A motor driving PTEN. Nature Cell Biology. 11: 1177-9. PMID 19794503 DOI: 10.1038/ncb1009-1177  1
2009 Lauchle JO, Kim D, Le DT, Akagi K, Crone M, Krisman K, Warner K, Bonifas JM, Li Q, Coakley KM, Diaz-Flores E, Gorman M, Przybranowski S, Tran M, Kogan SC, ... ... Parada L, et al. Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature. 461: 411-4. PMID 19727076 DOI: 10.1038/Nature08279  1
2009 Zhou J, Brugarolas J, Parada LF. Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1. Human Molecular Genetics. 18: 4428-41. PMID 19692352 DOI: 10.1093/Hmg/Ddp398  1
2009 Lin L, Chen J, Richardson JA, Parada LF. Mice lacking neurofibromin develop gastric hyperplasia. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G751-61. PMID 19661150 DOI: 10.1152/ajpgi.00007.2009  1
2009 Le LQ, Shipman T, Burns DK, Parada LF. Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas. Cell Stem Cell. 4: 453-63. PMID 19427294 DOI: 10.1016/J.Stem.2009.03.017  1
2009 Bodempudi V, Yamoutpoor F, Pan W, Dudek AZ, Esfandyari T, Piedra M, Babovick-Vuksanovic D, Woo RA, Mautner VF, Kluwe L, Clapp DW, De Vries GH, Thomas SL, Kurtz A, Parada LF, et al. Ral overactivation in malignant peripheral nerve sheath tumors. Molecular and Cellular Biology. 29: 3964-74. PMID 19414599 DOI: 10.1128/Mcb.01153-08  1
2009 Zhou J, Blundell J, Ogawa S, Kwon CH, Zhang W, Sinton C, Powell CM, Parada LF. Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1773-83. PMID 19211884 DOI: 10.1523/JNEUROSCI.5685-08.2009  1
2009 Chen J, Kwon CH, Lin L, Li Y, Parada LF. Inducible site-specific recombination in neural stem/progenitor cells. Genesis (New York, N.Y. : 2000). 47: 122-31. PMID 19117051 DOI: 10.1002/Dvg.20465  1
2009 Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell. 15: 45-56. PMID 19111880 DOI: 10.1016/J.Ccr.2008.12.006  1
2009 Graham DL, Krishnan V, Larson EB, Graham A, Edwards S, Bachtell RK, Simmons D, Gent LM, Berton O, Bolanos CA, DiLeone RJ, Parada LF, Nestler EJ, Self DW. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biological Psychiatry. 65: 696-701. PMID 18990365 DOI: 10.1016/J.Biopsych.2008.09.032  1
2009 Llaguno SA, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model (DOI:10.1016/j.ccr.2008.12.006) Cancer Cell. 15: 240. DOI: 10.1016/J.Ccr.2009.02.008  1
2008 Parrinello S, Noon LA, Harrisingh MC, Wingfield Digby P, Rosenberg LH, Cremona CA, Echave P, Flanagan AM, Parada LF, Lloyd AC. NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F. Genes & Development. 22: 3335-48. PMID 19056885 DOI: 10.1101/Gad.490608  1
2008 Llaguno SA, Chen J, Kwon CH, Parada LF. Neural and cancer stem cells in tumor suppressor mouse models of malignant astrocytoma. Cold Spring Harbor Symposia On Quantitative Biology. 73: 421-6. PMID 19022744 DOI: 10.1101/Sqb.2008.73.005  1
2008 Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A. Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes. The American Journal of Pathology. 173: 1861-72. PMID 18988803 DOI: 10.2353/ajpath.2008.080376  1
2008 Cui Y, Costa RM, Murphy GG, Elgersma Y, Zhu Y, Gutmann DH, Parada LF, Mody I, Silva AJ. Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell. 135: 549-60. PMID 18984165 DOI: 10.1016/J.Cell.2008.09.060  1
2008 Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, ... ... Parada LF, et al. Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell. 135: 437-48. PMID 18984156 DOI: 10.1016/J.Cell.2008.08.041  1
2008 Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron. 59: 399-412. PMID 18701066 DOI: 10.1016/J.Neuron.2008.06.023  1
2008 Luikart BW, Zhang W, Wayman GA, Kwon CH, Westbrook GL, Parada LF. Neurotrophin-dependent dendritic filopodial motility: a convergence on PI3K signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7006-12. PMID 18596174 DOI: 10.1523/Jneurosci.0195-08.2008  1
2008 Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF. Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Research. 68: 3286-94. PMID 18451155 DOI: 10.1158/0008-5472.Can-07-6867  1
2008 Lush ME, Li Y, Kwon CH, Chen J, Parada LF. Neurofibromin is required for barrel formation in the mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1580-7. PMID 18272679 DOI: 10.1523/Jneurosci.5236-07.2008  1
2008 Joseph NM, Mosher JT, Buchstaller J, Snider P, McKeever PE, Lim M, Conway SJ, Parada LF, Zhu Y, Morrison SJ. The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer Cell. 13: 129-40. PMID 18242513 DOI: 10.1016/J.Ccr.2008.01.003  1
2008 Parada LM, Liang X. Impacts of spatial resolutions and data quality on soil moisture data assimilation Journal of Geophysical Research Atmospheres. 113. DOI: 10.1029/2007Jd009037  0.72
2008 Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment (DOI:10.1016/j.neuron.2008.06.023) Neuron. 60: 730. DOI: 10.1016/J.Neuron.2008.10.021  1
2007 Ogawa S, Kwon CH, Zhou J, Koovakkattu D, Parada LF, Sinton CM. A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice. Brain Research. 1168: 112-23. PMID 17706614 DOI: 10.1016/J.Brainres.2007.06.074  1
2007 Cai J, Chen Y, Cai WH, Hurlock EC, Wu H, Kernie SG, Parada LF, Lu QR. A crucial role for Olig2 in white matter astrocyte development. Development (Cambridge, England). 134: 1887-99. PMID 17428828 DOI: 10.1242/Dev.02847  1
2007 Harada T, Harada C, Parada LF. Molecular regulation of visual system development: more than meets the eye. Genes & Development. 21: 367-78. PMID 17322396 DOI: 10.1101/gad.1504307  1
2007 Kolanczyk M, Kossler N, Kühnisch J, Lavitas L, Stricker S, Wilkening U, Manjubala I, Fratzl P, Spörle R, Herrmann BG, Parada LF, Kornak U, Mundlos S. Multiple roles for neurofibromin in skeletal development and growth. Human Molecular Genetics. 16: 874-86. PMID 17317783 DOI: 10.1093/Hmg/Ddm032  1
2007 Romero MI, Lin L, Lush ME, Lei L, Parada LF, Zhu Y. Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2124-34. PMID 17314307 DOI: 10.1523/JNEUROSCI.4363-06.2007  1
2007 Le LQ, Parada LF. Tumor microenvironment and neurofibromatosis type I: connecting the GAPs. Oncogene. 26: 4609-16. PMID 17297459 DOI: 10.1038/Sj.Onc.1210261  1
2007 Lei L, Parada LF. Transcriptional regulation of Trk family neurotrophin receptors. Cellular and Molecular Life Sciences : Cmls. 64: 522-32. PMID 17192812 DOI: 10.1007/s00018-006-6328-8  1
2007 Kim A, Morgan K, Hasz DE, Wiesner SM, Lauchle JO, Geurts JL, Diers MD, Le DT, Kogan SC, Parada LF, Shannon K, Largaespada DA. Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice. Blood. 109: 1687-91. PMID 17090653 DOI: 10.1182/Blood-2006-05-025395  1
2007 Monteggia LM, Luikart B, Barrot M, Theobold D, Malkovska I, Nef S, Parada LF, Nestler EJ. Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biological Psychiatry. 61: 187-97. PMID 16697351 DOI: 10.1016/J.Biopsych.2006.03.021  1
2006 Luikart BW, Parada LF. Receptor tyrosine kinase B-mediated excitatory synaptogenesis. Progress in Brain Research. 157: 15-24. PMID 17167900 DOI: 10.1016/S0079-6123(06)57002-5  1
2006 Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metabolism. 4: 441-51. PMID 17141628 DOI: 10.1016/J.Cmet.2006.10.010  1
2006 Lei L, Zhou J, Lin L, Parada LF. Brn3a and Klf7 cooperate to control TrkA expression in sensory neurons. Developmental Biology. 300: 758-69. PMID 17011544 DOI: 10.1016/j.ydbio.2006.08.062  1
2006 Bingham NC, Verma-Kurvari S, Parada LF, Parker KL. Development of a steroidogenic factor 1/Cre transgenic mouse line. Genesis (New York, N.Y. : 2000). 44: 419-24. PMID 16937416 DOI: 10.1002/dvg.20231  1
2006 Tran PV, Akana SF, Malkovska I, Dallman MF, Parada LF, Ingraham HA. Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF-1 gene dosage. The Journal of Comparative Neurology. 498: 637-48. PMID 16917842 DOI: 10.1002/Cne.21070  1
2006 Wagner E, Luo T, Sakai Y, Parada LF, Dräger UC. Retinoic acid delineates the topography of neuronal plasticity in postnatal cerebral cortex. The European Journal of Neuroscience. 24: 329-40. PMID 16836633 DOI: 10.1111/j.1460-9568.2006.04934.x  1
2006 Yang FC, Chen S, Clegg T, Li X, Morgan T, Estwick SA, Yuan J, Khalaf W, Burgin S, Travers J, Parada LF, Ingram DA, Clapp DW. Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. Human Molecular Genetics. 15: 2421-37. PMID 16835260 DOI: 10.1093/hmg/ddl165  1
2006 Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, Li Y, Baker SJ, Parada LF. Pten regulates neuronal arborization and social interaction in mice. Neuron. 50: 377-88. PMID 16675393 DOI: 10.1016/J.Neuron.2006.03.023  1
2006 Kwon CH, Zhou J, Li Y, Kim KW, Hensley LL, Baker SJ, Parada LF. Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis (New York, N.Y. : 2000). 44: 130-5. PMID 16496331 DOI: 10.1002/Gene.20197  1
2006 Yue T, Xian K, Hurlock E, Xin M, Kernie SG, Parada LF, Lu QR. A critical role for dorsal progenitors in cortical myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1275-80. PMID 16436615 DOI: 10.1523/Jneurosci.4717-05.2006  1
2006 Malkovska I, Kernie SG, Parada LF. Differential expression of the four untranslated BDNF exons in the adult mouse brain. Journal of Neuroscience Research. 83: 211-21. PMID 16385578 DOI: 10.1002/Jnr.20728  1
2006 Harada C, Harada T, Nakamura K, Sakai Y, Tanaka K, Parada LF. Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye. Developmental Biology. 290: 57-65. PMID 16343477 DOI: 10.1016/j.ydbio.2005.08.051  1
2006 Dissen GA, Garcia-Rudaz C, Tapia V, Parada LF, Hsu SY, Ojeda SR. Expression of the insulin receptor-related receptor is induced by the preovulatory surge of luteinizing hormone in thecal-interstitial cells of the rat ovary. Endocrinology. 147: 155-65. PMID 16195402 DOI: 10.1210/en.2005-0386  1
2005 Parada LF, Kwon CH, Zhu Y. Modeling neurofibromatosis type 1 tumors in the mouse for therapeutic intervention. Cold Spring Harbor Symposia On Quantitative Biology. 70: 173-6. PMID 16869751 DOI: 10.1101/sqb.2005.70.025  1
2005 Verma-Kurvari S, Nef S, Parada LF. Hormonal regulation of male reproductive tract development. Annals of the New York Academy of Sciences. 1061: 1-8. PMID 16467252 DOI: 10.1196/annals.1336.002  0.68
2005 Zhu Y, Harada T, Liu L, Lush ME, Guignard F, Harada C, Burns DK, Bajenaru ML, Gutmann DH, Parada LF. Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation. Development (Cambridge, England). 132: 5577-88. PMID 16314489 DOI: 10.1242/Dev.02162  1
2005 Zhu Y, Guignard F, Zhao D, Liu L, Burns DK, Mason RP, Messing A, Parada LF. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell. 8: 119-30. PMID 16098465 DOI: 10.1016/J.Ccr.2005.07.004  1
2005 Benson MD, Romero MI, Lush ME, Lu QR, Henkemeyer M, Parada LF. Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 102: 10694-9. PMID 16020529 DOI: 10.1073/Pnas.0504021102  1
2005 Lush ME, Ma L, Parada LF. TrkB signaling regulates the developmental maturation of the somatosensory cortex. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 23: 523-36. PMID 16009525 DOI: 10.1016/j.ijdevneu.2005.04.003  0.72
2005 Laub F, Lei L, Sumiyoshi H, Kajimura D, Dragomir C, Smaldone S, Puche AC, Petros TJ, Mason C, Parada LF, Ramirez F. Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Molecular and Cellular Biology. 25: 5699-711. PMID 15964824 DOI: 10.1128/Mcb.25.13.5699-5711.2005  1
2005 Shi J, Parada LF, Kernie SG. Bax limits adult neural stem cell persistence through caspase and IP3 receptor activation. Cell Death and Differentiation. 12: 1601-12. PMID 15947791 DOI: 10.1038/Sj.Cdd.4401676  1
2005 Lei L, Laub F, Lush M, Romero M, Zhou J, Luikart B, Klesse L, Ramirez F, Parada LF. The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons. Genes & Development. 19: 1354-64. PMID 15937222 DOI: 10.1101/Gad.1227705  1
2005 Luikart BW, Nef S, Virmani T, Lush ME, Liu Y, Kavalali ET, Parada LF. TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3774-86. PMID 15829629 DOI: 10.1523/Jneurosci.0041-05.2005  1
2005 Yu TS, Dandekar M, Monteggia LM, Parada LF, Kernie SG. Temporally regulated expression of Cre recombinase in neural stem cells. Genesis (New York, N.Y. : 2000). 41: 147-53. PMID 15789426 DOI: 10.1002/Gene.20110  1
2004 He XP, Kotloski R, Nef S, Luikart BW, Parada LF, McNamara JO. Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. Neuron. 43: 31-42. PMID 15233915 DOI: 10.1016/J.Neuron.2004.06.019  1
2004 Danzer SC, Pan E, Nef S, Parada LF, McNamara JO. Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation. Neuroscience. 126: 859-69. PMID 15207321 DOI: 10.1016/j.neuroscience.2004.03.025  1
2004 Le DT, Kong N, Zhu Y, Lauchle JO, Aiyigari A, Braun BS, Wang E, Kogan SC, Le Beau MM, Parada L, Shannon KM. Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder. Blood. 103: 4243-50. PMID 14982883 DOI: 10.1182/Blood-2003-08-2650  1
2003 Bajenaru ML, Hernandez MR, Perry A, Zhu Y, Parada LF, Garbow JR, Gutmann DH. Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. Cancer Research. 63: 8573-7. PMID 14695164  1
2003 Nef S, Verma-Kurvari S, Merenmies J, Vassalli JD, Efstratiadis A, Accili D, Parada LF. Testis determination requires insulin receptor family function in mice. Nature. 426: 291-5. PMID 14628051 DOI: 10.1038/Nature02059  1
2003 Harada C, Harada T, Quah HM, Maekawa F, Yoshida K, Ohno S, Wada K, Parada LF, Tanaka K. Potential role of glial cell line-derived neurotrophic factor receptors in Müller glial cells during light-induced retinal degeneration. Neuroscience. 122: 229-35. PMID 14596863 DOI: 10.1016/S0306-4522(03)00599-2  1
2003 Ma L, Lei L, Eng SR, Turner E, Parada LF. Brn3a regulation of TrkA/NGF receptor expression in developing sensory neurons. Development (Cambridge, England). 130: 3525-34. PMID 12810599 DOI: 10.1242/Dev.00582  1
2003 Luikart BW, Nef S, Shipman T, Parada LF. In vivo role of truncated trkb receptors during sensory ganglion neurogenesis. Neuroscience. 117: 847-58. PMID 12654337 DOI: 10.1016/S0306-4522(02)00719-4  0.96
2003 Liebl DJ, Morris CJ, Henkemeyer M, Parada LF. mRNA expression of ephrins and Eph receptor tyrosine kinases in the neonatal and adult mouse central nervous system. Journal of Neuroscience Research. 71: 7-22. PMID 12478610 DOI: 10.1002/Jnr.10457  1
2003 Gitler AD, Zhu Y, Ismat FA, Lu MM, Yamauchi Y, Parada LF, Epstein JA. Nf1 has an essential role in endothelial cells. Nature Genetics. 33: 75-9. PMID 12469121 DOI: 10.1038/Ng1059  1
2002 Ma L, Harada T, Harada C, Romero M, Hebert JM, McConnell SK, Parada LF. Neurotrophin-3 is required for appropriate establishment of thalamocortical connections. Neuron. 36: 623-34. PMID 12441052 DOI: 10.1016/S0896-6273(02)01021-8  1
2002 Harada T, Harada C, Kohsaka S, Wada E, Yoshida K, Ohno S, Mamada H, Tanaka K, Parada LF, Wada K. Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9228-36. PMID 12417648 DOI: 10.1523/Jneurosci.22-21-09228.2002  1
2002 Nguyen MT, Showalter PR, Timmons CF, Nef S, Parada LF, Baker LA. Effects of orchiopexy on congenitally cryptorchid insulin-3 knockout mice. The Journal of Urology. 168: 1779-83; discussion . PMID 12352358 DOI: 10.1097/01.ju.0000028337.05764.e9  0.68
2002 Zhu Y, Parada LF. The molecular and genetic basis of neurological tumours. Nature Reviews. Cancer. 2: 616-26. PMID 12154354 DOI: 10.1038/nrc866  1
2002 Bajenaru ML, Zhu Y, Hedrick NM, Donahoe J, Parada LF, Gutmann DH. Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. Molecular and Cellular Biology. 22: 5100-13. PMID 12077339 DOI: 10.1128/Mcb.22.14.5100-5113.2002  1
2002 Baker LA, Nef S, Nguyen MT, Stapleton R, Nordenskjold A, Pohl H, Parada LF. The insulin-3 gene: lack of a genetic basis for human cryptorchidism. The Journal of Urology. 167: 2534-7. PMID 11992081  0.68
2002 Zhu Y, Ghosh P, Charnay P, Burns DK, Parada LF. Neurofibromas in NF1: Schwann cell origin and role of tumor environment. Science (New York, N.Y.). 296: 920-2. PMID 11988578 DOI: 10.1126/Science.1068452  1
2001 Gutmann DH, Wu YL, Hedrick NM, Zhu Y, Guha A, Parada LF. Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes. Human Molecular Genetics. 10: 3009-16. PMID 11751683 DOI: 10.1093/Hmg/10.26.3009  1
2001 Kernie SG, Erwin TM, Parada LF. Brain remodeling due to neuronal and astrocytic proliferation after controlled cortical injury in mice. Journal of Neuroscience Research. 66: 317-26. PMID 11746349 DOI: 10.1002/Jnr.10013  1
2001 Honarpour N, Tabuchi K, Stark JM, Hammer RE, Südhof TC, Parada LF, Wang X, Richardson JA, Herz J. Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1. Neuroscience. 106: 263-74. PMID 11566499 DOI: 10.1016/S0306-4522(01)00275-5  0.84
2001 Plum LA, Parada LF, Tsoulfas P, Clagett-Dame M. Retinoic acid combined with neurotrophin-3 enhances the survival and neurite outgrowth of embryonic sympathetic neurons. Experimental Biology and Medicine (Maywood, N.J.). 226: 766-75. PMID 11520943 DOI: 10.1177/153537020222600809  1
2001 Kitamura T, Kido Y, Nef S, Merenmies J, Parada LF, Accili D. Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor. Molecular and Cellular Biology. 21: 5624-30. PMID 11463843 DOI: 10.1128/Mcb.21.16.5624-5630.2001  0.68
2001 Nef S, Lush ME, Shipman TE, Parada LF. Neurotrophins are not required for normal embryonic development of olfactory neurons. Developmental Biology. 234: 80-92. PMID 11356021 DOI: 10.1006/dbio.2001.0240  0.72
2001 Kubota Y, Nef S, Farmer PJ, Temelcos C, Parada LF, Hutson JM. Leydig insulin-like hormone, gubernacular development and testicular descent. The Journal of Urology. 165: 1673-5. PMID 11342953  1
2001 Zhu Y, Romero MI, Ghosh P, Ye Z, Charnay P, Rushing EJ, Marth JD, Parada LF. Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain. Genes & Development. 15: 859-76. PMID 11297510 DOI: 10.1101/Gad.862101  1
2001 Zhu Y, Parada LF. A particular GAP in mind. Nature Genetics. 27: 354-5. PMID 11279509 DOI: 10.1038/86835  1
2001 Lei L, Ma L, Nef S, Thai T, Parada LF. mKlf7, a potential transcriptional regulator of TrkA nerve growth factor receptor expression in sensory and sympathetic neurons. Development (Cambridge, England). 128: 1147-58. PMID 11245580  1
2001 Zhu Y, Parada LF. Neurofibromin, a tumor suppressor in the nervous system. Experimental Cell Research. 264: 19-28. PMID 11237520 DOI: 10.1006/excr.2000.5138  1
2001 Yokoyama N, Romero MI, Cowan CA, Galvan P, Helmbacher F, Charnay P, Parada LF, Henkemeyer M. Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline. Neuron. 29: 85-97. PMID 11182083 DOI: 10.1016/S0896-6273(01)00182-9  1
2000 Nef S, Parada LF. Hormones in male sexual development. Genes & Development. 14: 3075-86. PMID 11124800  0.68
2000 Ma L, Merenmies J, Parada LF. Molecular characterization of the TrkA/NGF receptor minimal enhancer reveals regulation by multiple cis elements to drive embryonic neuron expression. Development (Cambridge, England). 127: 3777-88. PMID 10934022  0.52
2000 Nef S, Shipman T, Parada LF. A molecular basis for estrogen-induced cryptorchidism. Developmental Biology. 224: 354-61. PMID 10926772 DOI: 10.1006/dbio.2000.9785  0.68
2000 Bates CM, Kharzai S, Erwin T, Rossant J, Parada LF. Role of N-myc in the developing mouse kidney. Developmental Biology. 222: 317-25. PMID 10837121 DOI: 10.1006/Dbio.2000.9716  1
2000 Kernie SG, Parada LF. The molecular basis for understanding neurotrophins and their relevance to neurologic disease. Archives of Neurology. 57: 654-7. PMID 10815130 DOI: 10.1001/Archneur.57.5.654  1
2000 Kernie SG, Liebl DJ, Parada LF. BDNF regulates eating behavior and locomotor activity in mice. The Embo Journal. 19: 1290-300. PMID 10716929 DOI: 10.1093/Emboj/19.6.1290  1
2000 Gonzalez-Zulueta M, Feldman AB, Klesse LJ, Kalb RG, Dillman JF, Parada LF, Dawson TM, Dawson VL. Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 97: 436-41. PMID 10618436 DOI: 10.1073/Pnas.97.1.436  1
1999 Kelly-Spratt KS, Klesse LJ, Merenmies J, Parada LF. A TrkB/insulin receptor-related receptor chimeric receptor induces PC12 cell differentiation and exhibits prolonged activation of mitogen-activated protein kinase. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 10: 805-12. PMID 10616905  0.48
1999 Ma L, Reis G, Parada LF, Schuman EM. Neuronal NT-3 is not required for synaptic transmission or long-term potentiation in area CA1 of the adult rat hippocampus. Learning & Memory (Cold Spring Harbor, N.Y.). 6: 267-75. PMID 10492008 DOI: 10.1101/Lm.6.3.267  1
1999 Liebl DJ, Mbiene JP, Parada LF. NT4/5 mutant mice have deficiency in gustatory papillae and taste bud formation. Developmental Biology. 213: 378-89. PMID 10479455 DOI: 10.1006/dbio.1999.9385  1
1999 Nef S, Parada LF. Cryptorchidism in mice mutant for Insl3. Nature Genetics. 22: 295-9. PMID 10391220 DOI: 10.1038/10364  0.68
1999 Kahn MA, Kumar S, Liebl D, Chang R, Parada LF, De Vellis J. Mice lacking NT-3, and its receptor TrkC, exhibit profound deficiencies in CNS glial cells. Glia. 26: 153-65. PMID 10384880 DOI: 10.1002/(Sici)1098-1136(199904)26:2<153::Aid-Glia6>3.0.Co;2-Z  1
1998 Zhu Y, Richardson JA, Parada LF, Graff JM. Smad3 mutant mice develop metastatic colorectal cancer. Cell. 94: 703-14. PMID 9753318 DOI: 10.1016/S0092-8674(00)81730-4  1
1997 Tessarollo L, Tsoulfas P, Donovan MJ, Palko ME, Blair-Flynn J, Hempstead BL, Parada LF. Targeted deletion of all isoforms of the trkC gene suggests the use of alternate receptors by its ligand neurotrophin-3 in neuronal development and implicates trkC in normal cardiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 94: 14776-81. PMID 9405689 DOI: 10.1073/Pnas.94.26.14776  1
1997 Merenmies J, Parada LF, Henkemeyer M. Receptor tyrosine kinase signaling in vascular development. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 8: 3-10. PMID 8993829  1
1996 Nelson CE, Morgan BA, Burke AC, Laufer E, DiMambro E, Murtaugh LC, Gonzales E, Tessarollo L, Parada LF, Tabin C. Analysis of Hox gene expression in the chick limb bud. Development (Cambridge, England). 122: 1449-66. PMID 8625833  1
1996 Tsoulfas P, Stephens RM, Kaplan DR, Parada LF. TrkC isoforms with inserts in the kinase domain show impaired signaling responses. The Journal of Biological Chemistry. 271: 5691-7. PMID 8621434 DOI: 10.1074/Jbc.271.10.5691  1
1995 Donovan MJ, Miranda RC, Kraemer R, McCaffrey TA, Tessarollo L, Mahadeo D, Sharif S, Kaplan DR, Tsoulfas P, Parada L. Neurotrophin and neurotrophin receptors in vascular smooth muscle cells. Regulation of expression in response to injury. The American Journal of Pathology. 147: 309-24. PMID 7639328  1
1994 Xu H, Federoff H, Maragos J, Parada LF, Kessler JA. Viral transduction of trkA into cultured nodose and spinal motor neurons conveys NGF responsiveness. Developmental Biology. 163: 152-61. PMID 8174770 DOI: 10.1006/Dbio.1994.1131  1
1994 Averbuch-Heller L, Pruginin M, Kahane N, Tsoulfas P, Parada L, Rosenthal A, Kalcheim C. Neurotrophin 3 stimulates the differentiation of motoneurons from avian neural tube progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 3247-51. PMID 8159733 DOI: 10.1073/Pnas.91.8.3247  1
1994 Escandón E, Soppet D, Rosenthal A, Mendoza-Ramírez JL, Szönyi E, Burton LE, Henderson CE, Parada LF, Nikolics K. Regulation of neurotrophin receptor expression during embryonic and postnatal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2054-68. PMID 8158256  1
1994 Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, Reid SW, Buchberg AM, Jenkins NA, Parada LF, Copeland NG. Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes & Development. 8: 1019-29. PMID 7926784 DOI: 10.1101/Gad.8.9.1019  1
1994 Urfer R, Tsoulfas P, Soppet D, Escandón E, Parada LF, Presta LG. The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin. The Embo Journal. 13: 5896-909. PMID 7529173  0.32
1993 Tsoulfas P, Soppet D, Escandon E, Tessarollo L, Mendoza-Ramirez JL, Rosenthal A, Nikolics K, Parada LF. The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells. Neuron. 10: 975-90. PMID 8494648 DOI: 10.1016/0896-6273(93)90212-A  1
1993 Lindholm D, Castrén E, Tsoulfas P, Kolbeck R, Berzaghi Mda P, Leingärtner A, Heisenberg CP, Tessarollo L, Parada LF, Thoenen H, Tesarollo L. Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation. The Journal of Cell Biology. 122: 443-50. PMID 8320266 DOI: 10.1083/Jcb.122.2.443  1
1993 Moens CB, Stanton BR, Parada LF, Rossant J. Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus. Development (Cambridge, England). 119: 485-99. PMID 8287798  1
1993 Zhou XF, Parada LF, Soppet D, Rush RA. Distribution of trkB tyrosine kinase immunoreactivity in the rat central nervous system. Brain Research. 622: 63-70. PMID 8242385  0.32
1992 Tessarollo L, Nagarajan L, Parada LF. c-ros: the vertebrate homolog of the sevenless tyrosine kinase receptor is tightly regulated during organogenesis in mouse embryonic development. Development (Cambridge, England). 115: 11-20. PMID 1638975  1
1992 Holtzman DM, Li Y, Parada LF, Kinsman S, Chen CK, Valletta JS, Zhou J, Long JB, Mobley WC. p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF. Neuron. 9: 465-78. PMID 1524827 DOI: 10.1016/0896-6273(92)90184-F  1
1992 Stanton BR, Perkins AS, Tessarollo L, Sassoon DA, Parada LF. Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes & Development. 6: 2235-47. PMID 1459449  1
1992 Hempstead BL, Rabin SJ, Kaplan L, Reid S, Parada LF, Kaplan DR. Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation. Neuron. 9: 883-96. PMID 1384575 DOI: 10.1016/0896-6273(92)90241-5  1
1992 Parada LF, Tsoulfas P, Tessarollo L, Blair J, Reid SW, Soppet D. The Trk family of tyrosine kinases: receptors for NGF-related neurotrophins. Cold Spring Harbor Symposia On Quantitative Biology. 57: 43-51. PMID 1339678 DOI: 10.1101/Sqb.1992.057.01.006  0.32
1991 Hempstead BL, Martin-Zanca D, Kaplan DR, Parada LF, Chao MV. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature. 350: 678-83. PMID 1850821 DOI: 10.1038/350678A0  1
1991 Kaplan DR, Hempstead BL, Martin-Zanca D, Chao MV, Parada LF. The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science (New York, N.Y.). 252: 554-8. PMID 1850549 DOI: 10.1126/Science.1850549  1
1991 Vetter ML, Martin-Zanca D, Parada LF, Bishop JM, Kaplan DR. Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene. Proceedings of the National Academy of Sciences of the United States of America. 88: 5650-4. PMID 1712104  1
1990 Martin-Zanca D, Barbacid M, Parada LF. Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development. Genes & Development. 4: 683-94. PMID 2379826 DOI: 10.1101/Gad.4.5.683  1
1990 Klein R, Martin-Zanca D, Barbacid M, Parada LF. Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system. Development (Cambridge, England). 109: 845-50. PMID 2171894  1
1990 Klein R, Conway D, Parada LF, Barbacid M. The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain. Cell. 61: 647-56. PMID 2160854 DOI: 10.1016/0092-8674(90)90476-U  1
1989 Klein R, Parada LF, Coulier F, Barbacid M. trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development. The Embo Journal. 8: 3701-9. PMID 2555172  1
1986 Land H, Chen AC, Morgenstern JP, Parada LF, Weinberg RA. Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts. Molecular and Cellular Biology. 6: 1917-25. PMID 3785184 DOI: 10.1128/Mcb.6.6.1917  0.92
1985 Dotto GP, Parada LF, Weinberg RA. Specific growth response of ras-transformed embryo fibroblasts to tumour promoters. Nature. 318: 472-5. PMID 4069218 DOI: 10.1038/318472A0  0.92
1985 Parada LF, Land H, Chen A, Morganstern J, Weinberg RA. Cooperation between cellular oncogenes in the transformation of primary rat embryo fibroblasts. Progress in Medical Virology. Fortschritte Der Medizinischen Virusforschung. Progrã¨S En Virologie Mã©Dicale. 32: 115-28. PMID 4023262  0.92
1984 Parada LF, Land H, Weinberg RA, Wolf D, Rotter V. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature. 312: 649-51. PMID 6390217 DOI: 10.1038/312649A0  1
1984 Lenoir GM, Land H, Parada LF, Cunningham JM, Weinberg RA. Activated oncogenes in Burkitt's lymphoma. Current Topics in Microbiology and Immunology. 113: 6-14. PMID 6090072 DOI: 10.1007/978-3-642-69860-6_2  0.92
1983 Murray MJ, Cunningham JM, Parada LF, Dautry F, Lebowitz P, Weinberg RA. The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell. 33: 749-57. PMID 6683594 DOI: 10.1016/0092-8674(83)90017-X  0.92
1983 Parada LF, Shih C, Murray M, Weinberg RA. The oncogene of a human bladder carcinoma. Progress in Nucleic Acid Research and Molecular Biology. 29: 269-72. PMID 6665172 DOI: 10.1016/S0079-6603(08)60458-4  0.92
1983 Land H, Parada LF, Weinberg RA. Cellular oncogenes and multistep carcinogenesis. Science (New York, N.Y.). 222: 771-8. PMID 6356358 DOI: 10.1126/Science.6356358  0.92
1983 Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 304: 596-602. PMID 6308472 DOI: 10.1038/304596A0  0.92
1983 Parada LF, Weinberg RA. Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene. Molecular and Cellular Biology. 3: 2298-301. PMID 6197628  0.92
1982 Parada LF, Tabin CJ, Shih C, Weinberg RA. Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene. Nature. 297: 474-8. PMID 6283357 DOI: 10.1038/297474A0  1
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