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Luis Parada, Ph.D. - Publications

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Developmental Biology
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65/327 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sun D, Xie XP, Zhang X, Wang Z, Sait SF, Iyer SV, Chen YJ, Brown R, Laks DR, Chipman ME, Shern JF, Parada LF. Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression. Cell Stem Cell. PMID 34010628 DOI: 10.1016/j.stem.2021.04.029  0.63
2020 Wang Z, Sun D, Chen YJ, Xie X, Shi Y, Tabar V, Brennan CW, Bale TA, Jayewickreme CD, Laks DR, Alcantara Llaguno S, Parada LF. Cell Lineage-Based Stratification for Glioblastoma. Cancer Cell. PMID 32649888 DOI: 10.1016/J.Ccell.2020.06.003  0.636
2020 Sait SF, Tang K, Brown R, Sun D, Xie X, Neel B, Parada L. Abstract 1889: Allosteric inhibition of SHP2 prevents adaptive resistance to MEK inhibition in neurofibromatosis type 1 associated malignant peripheral nerve sheath tumors Cancer Research. 80: 1889-1889. DOI: 10.1158/1538-7445.Am2020-1889  0.34
2019 Shi Y, Lim SK, Liang Q, Iyer SV, Wang HY, Wang Z, Xie X, Sun D, Chen YJ, Tabar V, Gutin P, Williams N, De Brabander JK, Parada LF. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. PMID 30842654 DOI: 10.1038/S41586-019-0993-X  0.608
2019 Llaguno SA, Sun D, Pedraza AM, Vera E, Wang Z, Burns DK, Parada LF. Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction. Nature Neuroscience. PMID 30778149 DOI: 10.1038/S41593-018-0333-8  0.303
2018 Sun D, Parada L. Abstract B14: A restricted cell population propagates MPNST growth after treatment Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-B14  0.315
2017 Ma Z, Zang T, Birnbaum SG, Wang Z, Johnson JE, Zhang CL, Parada LF. TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response. Nature Communications. 8: 1668. PMID 29162814 DOI: 10.1038/S41467-017-01709-8  0.653
2016 Llaguno SA, Wang Z, Sun D, Chen J, Pedraza A, Xu J, Kim E, Hatanpaa K, Raisanen J, Burns D, Johnson J, Parada L. TMOD-07. CELLULAR ORIGINS OF GLIOBLASTOMA: LESSONS FROM MOUSE MODELS Neuro-Oncology. 18: vi208-vi208. DOI: 10.1093/Neuonc/Now212.877  0.46
2015 Alcantara Llaguno SR, Wang Z, Sun D, Chen J, Xu J, Kim E, Hatanpaa KJ, Raisanen JM, Burns DK, Johnson JE, Parada LF. Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes. Cancer Cell. 28: 429-40. PMID 26461091 DOI: 10.1016/J.Ccell.2015.09.007  0.461
2014 Anastasia A, Deinhardt K, Wang S, Martin L, Nichol D, Irmady K, Trinh J, Parada L, Rafii S, Hempstead BL, Kermani P. Trkb signaling in pericytes is required for cardiac microvessel stabilization. Plos One. 9: e87406. PMID 24498100 DOI: 10.1371/Journal.Pone.0087406  0.357
2014 Amiri A, Sanchez-Ortiz E, Cho W, Birnbaum SG, Xu J, McKay RM, Parada LF. Analysis of FMR1 deletion in a subpopulation of post-mitotic neurons in mouse cortex and hippocampus. Autism Research : Official Journal of the International Society For Autism Research. 7: 60-71. PMID 24408886 DOI: 10.1002/aur.1342  0.342
2014 Haws ME, Jaramillo TC, Espinosa F, Widman AJ, Stuber GD, Sparta DR, Tye KM, Russo SJ, Parada LF, Stavarache M, Kaplitt M, Bonci A, Powell CM. PTEN knockdown alters dendritic spine/protrusion morphology, not density. The Journal of Comparative Neurology. 522: 1171-90. PMID 24264880 DOI: 10.1002/Cne.23488  0.537
2013 Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, ... Parada LF, et al. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 152: 1077-90. PMID 23434321 DOI: 10.1016/J.Cell.2013.01.053  0.326
2012 Li Y, Yui D, Luikart BW, McKay RM, Li Y, Rubenstein JL, Parada LF. Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development. Proceedings of the National Academy of Sciences of the United States of America. 109: 15491-6. PMID 22949667 DOI: 10.1073/Pnas.1212899109  0.696
2012 Chen J, Li Y, Yu TS, McKay RM, Burns DK, Kernie SG, Parada LF. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature. 488: 522-6. PMID 22854781 DOI: 10.1038/Nature11287  0.304
2012 Sanchez-Ortiz E, Yui D, Song D, Li Y, Rubenstein JL, Reichardt LF, Parada LF. TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4065-79. PMID 22442072 DOI: 10.1523/Jneurosci.6314-11.2012  0.327
2012 Li Y, Li Y, McKay RM, Riethmacher D, Parada LF. Neurofibromin modulates adult hippocampal neurogenesis and behavioral effects of antidepressants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3529-39. PMID 22399775 DOI: 10.1523/Jneurosci.3469-11.2012  0.376
2011 Zhou J, Shrikhande G, Xu J, McKay RM, Burns DK, Johnson JE, Parada LF. Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle. Genes & Development. 25: 1595-600. PMID 21828270 DOI: 10.1101/Gad.16750211  0.414
2011 Luikart BW, Bensen AL, Washburn EK, Perederiy JV, Su KG, Li Y, Kernie SG, Parada LF, Westbrook GL. miR-132 mediates the integration of newborn neurons into the adult dentate gyrus. Plos One. 6: e19077. PMID 21611182 DOI: 10.1371/Journal.Pone.0019077  0.712
2011 Blaiss CA, Yu TS, Zhang G, Chen J, Dimchev G, Parada LF, Powell CM, Kernie SG. Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4906-16. PMID 21451029 DOI: 10.1523/Jneurosci.5265-10.2011  0.505
2011 Harada C, Guo X, Namekata K, Kimura A, Nakamura K, Tanaka K, Parada LF, Harada T. Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration. Nature Communications. 2: 189. PMID 21304518 DOI: 10.1038/ncomms1190  0.306
2009 Choi SH, Li Y, Parada LF, Sisodia SS. Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF. Molecular Neurodegeneration. 4: 52. PMID 20025751 DOI: 10.1186/1750-1326-4-52  0.415
2009 Lauchle JO, Kim D, Le DT, Akagi K, Crone M, Krisman K, Warner K, Bonifas JM, Li Q, Coakley KM, Diaz-Flores E, Gorman M, Przybranowski S, Tran M, Kogan SC, ... ... Parada L, et al. Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature. 461: 411-4. PMID 19727076 DOI: 10.1038/Nature08279  0.332
2009 Zhou J, Blundell J, Ogawa S, Kwon CH, Zhang W, Sinton C, Powell CM, Parada LF. Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1773-83. PMID 19211884 DOI: 10.1523/JNEUROSCI.5685-08.2009  0.587
2009 Chen J, Kwon CH, Lin L, Li Y, Parada LF. Inducible site-specific recombination in neural stem/progenitor cells. Genesis (New York, N.Y. : 2000). 47: 122-31. PMID 19117051 DOI: 10.1002/Dvg.20465  0.354
2009 Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell. 15: 45-56. PMID 19111880 DOI: 10.1016/J.Ccr.2008.12.006  0.347
2008 Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron. 59: 399-412. PMID 18701066 DOI: 10.1016/J.Neuron.2008.06.023  0.701
2008 Luikart BW, Zhang W, Wayman GA, Kwon CH, Westbrook GL, Parada LF. Neurotrophin-dependent dendritic filopodial motility: a convergence on PI3K signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7006-12. PMID 18596174 DOI: 10.1523/Jneurosci.0195-08.2008  0.73
2008 Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF. Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Research. 68: 3286-94. PMID 18451155 DOI: 10.1158/0008-5472.Can-07-6867  0.331
2008 Lush ME, Li Y, Kwon CH, Chen J, Parada LF. Neurofibromin is required for barrel formation in the mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1580-7. PMID 18272679 DOI: 10.1523/Jneurosci.5236-07.2008  0.374
2008 Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment (DOI:10.1016/j.neuron.2008.06.023) Neuron. 60: 730. DOI: 10.1016/J.Neuron.2008.10.021  0.675
2007 Romero MI, Lin L, Lush ME, Lei L, Parada LF, Zhu Y. Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2124-34. PMID 17314307 DOI: 10.1523/JNEUROSCI.4363-06.2007  0.325
2007 Monteggia LM, Luikart B, Barrot M, Theobold D, Malkovska I, Nef S, Parada LF, Nestler EJ. Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biological Psychiatry. 61: 187-97. PMID 16697351 DOI: 10.1016/J.Biopsych.2006.03.021  0.641
2007 Yang F, Ingram D, Chen S, Robertson K, Li X, Yuan J, Knoll S, Horn W, Hutchins G, Parada L, Clapp DW. Imatinib Mesylate Reduces Plexiform Neurofibromas by Targeting the Hematopoietic Microenvironment. Blood. 110: 1915-1915. DOI: 10.1182/Blood.V110.11.1915.1915  0.345
2006 Luikart BW, Parada LF. Receptor tyrosine kinase B-mediated excitatory synaptogenesis. Progress in Brain Research. 157: 15-24. PMID 17167900 DOI: 10.1016/S0079-6123(06)57002-5  0.668
2006 Tran PV, Akana SF, Malkovska I, Dallman MF, Parada LF, Ingraham HA. Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF-1 gene dosage. The Journal of Comparative Neurology. 498: 637-48. PMID 16917842 DOI: 10.1002/Cne.21070  0.302
2006 Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, Li Y, Baker SJ, Parada LF. Pten regulates neuronal arborization and social interaction in mice. Neuron. 50: 377-88. PMID 16675393 DOI: 10.1016/J.Neuron.2006.03.023  0.742
2006 Kwon CH, Zhou J, Li Y, Kim KW, Hensley LL, Baker SJ, Parada LF. Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis (New York, N.Y. : 2000). 44: 130-5. PMID 16496331 DOI: 10.1002/Gene.20197  0.359
2006 Yang F, Ingram DA, Chen S, Yuan J, Li X, Horn W, Parada L, Clapp DW. Mast Cells Are Integral Components of the Tumor Microenvironment That Are Required for Plexiform Neurofibroma Progression. Blood. 108: 677-677. DOI: 10.1182/Blood.V108.11.677.677  0.338
2005 Lei L, Laub F, Lush M, Romero M, Zhou J, Luikart B, Klesse L, Ramirez F, Parada LF. The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons. Genes & Development. 19: 1354-64. PMID 15937222 DOI: 10.1101/Gad.1227705  0.68
2005 Luikart BW, Nef S, Virmani T, Lush ME, Liu Y, Kavalali ET, Parada LF. TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3774-86. PMID 15829629 DOI: 10.1523/Jneurosci.0041-05.2005  0.648
2005 Lauchle JO, Le D, Kim D, Tran M, Peterson A, Przybranowski S, Parada L, Wolff L, Leopold J, Shannon KM. Disease Stage Strongly Modulates Responsiveness to Targeted Agents in Nf1 Mutant Mice with Myeloprolfierative Disease (MPD) and Acute Myeloid Leukemia (AML). Blood. 106: 496-496. DOI: 10.1182/Blood.V106.11.496.496  0.343
2004 He XP, Kotloski R, Nef S, Luikart BW, Parada LF, McNamara JO. Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. Neuron. 43: 31-42. PMID 15233915 DOI: 10.1016/J.Neuron.2004.06.019  0.664
2004 Le DT, Kong N, Zhu Y, Lauchle JO, Aiyigari A, Braun BS, Wang E, Kogan SC, Le Beau MM, Parada L, Shannon KM. Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder. Blood. 103: 4243-50. PMID 14982883 DOI: 10.1182/Blood-2003-08-2650  0.367
2003 Luikart BW, Nef S, Shipman T, Parada LF. In vivo role of truncated trkb receptors during sensory ganglion neurogenesis. Neuroscience. 117: 847-58. PMID 12654337 DOI: 10.1016/S0306-4522(02)00719-4  0.674
2002 Kelly-Spratt KS, Klesse LJ, Parada LF. BDNF activated TrkB/IRR receptor chimera promotes survival of sympathetic neurons through Ras and PI-3 kinase signaling. Journal of Neuroscience Research. 69: 151-9. PMID 12111796 DOI: 10.1002/jnr.10172  0.305
2000 Liebl DJ, Klesse LJ, Tessarollo L, Wohlman T, Parada LF. Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 2297-302. PMID 10681461 DOI: 10.1073/pnas.040562597  0.318
1999 Liebl DJ, Mbiene JP, Parada LF. NT4/5 mutant mice have deficiency in gustatory papillae and taste bud formation. Developmental Biology. 213: 378-89. PMID 10479455 DOI: 10.1006/dbio.1999.9385  0.319
1999 Kahn MA, Kumar S, Liebl D, Chang R, Parada LF, De Vellis J. Mice lacking NT-3, and its receptor TrkC, exhibit profound deficiencies in CNS glial cells. Glia. 26: 153-65. PMID 10384880 DOI: 10.1002/(Sici)1098-1136(199904)26:2<153::Aid-Glia6>3.0.Co;2-Z  0.327
1998 Klesse LJ, Parada LF. p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10420-8. PMID 9852579  0.303
1997 Liebl DJ, Tessarollo L, Palko ME, Parada LF. Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9113-21. PMID 9364058  0.326
1995 Vogel KS, Brannan CI, Jenkins NA, Copeland NG, Parada LF. Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons. Cell. 82: 733-42. PMID 7671302 DOI: 10.1016/0092-8674(95)90470-0  0.325
1994 Tessarollo L, Vogel KS, Palko ME, Reid SW, Parada LF. Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 11844-8. PMID 7991545  0.305
1992 Holtzman DM, Li Y, Parada LF, Kinsman S, Chen CK, Valletta JS, Zhou J, Long JB, Mobley WC. p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF. Neuron. 9: 465-78. PMID 1524827 DOI: 10.1016/0896-6273(92)90184-F  0.365
1986 Land H, Chen AC, Morgenstern JP, Parada LF, Weinberg RA. Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts. Molecular and Cellular Biology. 6: 1917-25. PMID 3785184 DOI: 10.1128/Mcb.6.6.1917  0.423
1985 Dotto GP, Parada LF, Weinberg RA. Specific growth response of ras-transformed embryo fibroblasts to tumour promoters. Nature. 318: 472-5. PMID 4069218 DOI: 10.1038/318472A0  0.442
1985 Parada LF, Land H, Chen A, Morganstern J, Weinberg RA. Cooperation between cellular oncogenes in the transformation of primary rat embryo fibroblasts. Progress in Medical Virology. Fortschritte Der Medizinischen Virusforschung. Progrã¨S En Virologie Mã©Dicale. 32: 115-28. PMID 4023262  0.363
1984 Parada LF, Land H, Weinberg RA, Wolf D, Rotter V. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature. 312: 649-51. PMID 6390217 DOI: 10.1038/312649A0  0.42
1984 Lenoir GM, Land H, Parada LF, Cunningham JM, Weinberg RA. Activated oncogenes in Burkitt's lymphoma. Current Topics in Microbiology and Immunology. 113: 6-14. PMID 6090072 DOI: 10.1007/978-3-642-69860-6_2  0.403
1983 Murray MJ, Cunningham JM, Parada LF, Dautry F, Lebowitz P, Weinberg RA. The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell. 33: 749-57. PMID 6683594 DOI: 10.1016/0092-8674(83)90017-X  0.443
1983 Parada LF, Shih C, Murray M, Weinberg RA. The oncogene of a human bladder carcinoma. Progress in Nucleic Acid Research and Molecular Biology. 29: 269-72. PMID 6665172 DOI: 10.1016/S0079-6603(08)60458-4  0.387
1983 Land H, Parada LF, Weinberg RA. Cellular oncogenes and multistep carcinogenesis. Science (New York, N.Y.). 222: 771-8. PMID 6356358 DOI: 10.1126/Science.6356358  0.439
1983 Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 304: 596-602. PMID 6308472 DOI: 10.1038/304596A0  0.412
1983 Parada LF, Weinberg RA. Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene. Molecular and Cellular Biology. 3: 2298-301. PMID 6197628  0.422
1982 Parada LF, Tabin CJ, Shih C, Weinberg RA. Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene. Nature. 297: 474-8. PMID 6283357 DOI: 10.1038/297474A0  0.567
Low-probability matches (unlikely to be authored by this person)
2008 Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, ... ... Parada LF, et al. Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell. 135: 437-48. PMID 18984156 DOI: 10.1016/J.Cell.2008.08.041  0.295
2003 Ma L, Lei L, Eng SR, Turner E, Parada LF. Brn3a regulation of TrkA/NGF receptor expression in developing sensory neurons. Development (Cambridge, England). 130: 3525-34. PMID 12810599 DOI: 10.1242/Dev.00582  0.293
2000 Kernie SG, Liebl DJ, Parada LF. BDNF regulates eating behavior and locomotor activity in mice. The Embo Journal. 19: 1290-300. PMID 10716929 DOI: 10.1093/Emboj/19.6.1290  0.292
2013 Wang Y, Lin L, Lai H, Parada LF, Lei L. Transcription factor Sox11 is essential for both embryonic and adult neurogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 638-53. PMID 23483698 DOI: 10.1002/Dvdy.23962  0.292
2003 Bron R, Klesse LJ, Shah K, Parada LF, Winter J. Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors. Molecular and Cellular Neurosciences. 22: 118-32. PMID 12595244  0.291
1993 Lindholm D, Castrén E, Tsoulfas P, Kolbeck R, Berzaghi Mda P, Leingärtner A, Heisenberg CP, Tessarollo L, Parada LF, Thoenen H, Tesarollo L. Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation. The Journal of Cell Biology. 122: 443-50. PMID 8320266 DOI: 10.1083/Jcb.122.2.443  0.285
2000 Vogel KS, El-Afandi M, Parada LF. Neurofibromin negatively regulates neurotrophin signaling through p21ras in embryonic sensory neurons. Molecular and Cellular Neurosciences. 15: 398-407. PMID 10845775 DOI: 10.1006/mcne.2000.0836  0.285
2018 Xie X, Laks D, Sun D, Poran A, Laughney A, Belenguer G, Massague J, Zhou X, Farinas I, Elemento O, Parada L. TMOD-36. PRECISE INVESTIGATION OF CANCER STEM CELLS IN A MOUSE GLIOBLASTOMA MODEL Neuro-Oncology. 20: vi276-vi276. DOI: 10.1093/Neuonc/Noy148.1148  0.284
2013 Takeuchi K, Gertner MJ, Zhou J, Parada LF, Bennett MV, Zukin RS. Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism. Proceedings of the National Academy of Sciences of the United States of America. 110: 4738-43. PMID 23487788 DOI: 10.1073/pnas.1222803110  0.281
2005 Laub F, Lei L, Sumiyoshi H, Kajimura D, Dragomir C, Smaldone S, Puche AC, Petros TJ, Mason C, Parada LF, Ramirez F. Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Molecular and Cellular Biology. 25: 5699-711. PMID 15964824 DOI: 10.1128/Mcb.25.13.5699-5711.2005  0.281
1990 Martin-Zanca D, Barbacid M, Parada LF. Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development. Genes & Development. 4: 683-94. PMID 2379826 DOI: 10.1101/Gad.4.5.683  0.279
1999 Ma L, Reis G, Parada LF, Schuman EM. Neuronal NT-3 is not required for synaptic transmission or long-term potentiation in area CA1 of the adult rat hippocampus. Learning & Memory (Cold Spring Harbor, N.Y.). 6: 267-75. PMID 10492008 DOI: 10.1101/Lm.6.3.267  0.277
2014 Sanchez-Ortiz E, Cho W, Nazarenko I, Mo W, Chen J, Parada LF. NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development. Genes & Development. 28: 2407-20. PMID 25367036 DOI: 10.1101/gad.246603.114  0.276
2001 Honarpour N, Tabuchi K, Stark JM, Hammer RE, Südhof TC, Parada LF, Wang X, Richardson JA, Herz J. Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1. Neuroscience. 106: 263-74. PMID 11566499 DOI: 10.1016/S0306-4522(01)00275-5  0.276
1994 Escandón E, Soppet D, Rosenthal A, Mendoza-Ramírez JL, Szönyi E, Burton LE, Henderson CE, Parada LF, Nikolics K. Regulation of neurotrophin receptor expression during embryonic and postnatal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 2054-68. PMID 8158256  0.275
2012 Amiri A, Cho W, Zhou J, Birnbaum SG, Sinton CM, McKay RM, Parada LF. Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5880-90. PMID 22539849 DOI: 10.1523/JNEUROSCI.5462-11.2012  0.274
1998 Vogel KS, Parada LF. Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin. Molecular and Cellular Neurosciences. 11: 19-28. PMID 9608530 DOI: 10.1006/mcne.1998.0670  0.27
2001 Zhu Y, Romero MI, Ghosh P, Ye Z, Charnay P, Rushing EJ, Marth JD, Parada LF. Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain. Genes & Development. 15: 859-76. PMID 11297510 DOI: 10.1101/Gad.862101  0.266
2012 Gutmann DH, Parada LF, Silva AJ, Ratner N. Neurofibromatosis type 1: modeling CNS dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14087-93. PMID 23055477 DOI: 10.1523/Jneurosci.3242-12.2012  0.264
2012 Colombo E, Cordiglieri C, Melli G, Newcombe J, Krumbholz M, Parada LF, Medico E, Hohlfeld R, Meinl E, Farina C. Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration. The Journal of Experimental Medicine. 209: 521-35. PMID 22393127 DOI: 10.1084/Jem.20110698  0.263
1993 Zhou XF, Parada LF, Soppet D, Rush RA. Distribution of trkB tyrosine kinase immunoreactivity in the rat central nervous system. Brain Research. 622: 63-70. PMID 8242385  0.263
1997 Tessarollo L, Tsoulfas P, Donovan MJ, Palko ME, Blair-Flynn J, Hempstead BL, Parada LF. Targeted deletion of all isoforms of the trkC gene suggests the use of alternate receptors by its ligand neurotrophin-3 in neuronal development and implicates trkC in normal cardiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 94: 14776-81. PMID 9405689 DOI: 10.1073/Pnas.94.26.14776  0.263
2006 Lei L, Zhou J, Lin L, Parada LF. Brn3a and Klf7 cooperate to control TrkA expression in sensory neurons. Developmental Biology. 300: 758-69. PMID 17011544 DOI: 10.1016/j.ydbio.2006.08.062  0.263
2001 Lei L, Ma L, Nef S, Thai T, Parada LF. mKlf7, a potential transcriptional regulator of TrkA nerve growth factor receptor expression in sensory and sympathetic neurons. Development (Cambridge, England). 128: 1147-58. PMID 11245580  0.263
2004 Danzer SC, Pan E, Nef S, Parada LF, McNamara JO. Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation. Neuroscience. 126: 859-69. PMID 15207321 DOI: 10.1016/j.neuroscience.2004.03.025  0.261
1993 Tessarollo L, Tsoulfas P, Martin-Zanca D, Gilbert DJ, Jenkins NA, Copeland NG, Parada LF. trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues. Development (Cambridge, England). 118: 463-75. PMID 8223273  0.259
2001 Plum LA, Parada LF, Tsoulfas P, Clagett-Dame M. Retinoic acid combined with neurotrophin-3 enhances the survival and neurite outgrowth of embryonic sympathetic neurons. Experimental Biology and Medicine (Maywood, N.J.). 226: 766-75. PMID 11520943 DOI: 10.1177/153537020222600809  0.259
2015 Penzo MA, Robert V, Tucciarone J, De Bundel D, Wang M, Van Aelst L, Darvas M, Parada LF, Palmiter RD, He M, Huang ZJ, Li B. The paraventricular thalamus controls a central amygdala fear circuit. Nature. 519: 455-9. PMID 25600269 DOI: 10.1038/Nature13978  0.258
2005 Zhu Y, Guignard F, Zhao D, Liu L, Burns DK, Mason RP, Messing A, Parada LF. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell. 8: 119-30. PMID 16098465 DOI: 10.1016/J.Ccr.2005.07.004  0.257
2000 Ma L, Merenmies J, Parada LF. Molecular characterization of the TrkA/NGF receptor minimal enhancer reveals regulation by multiple cis elements to drive embryonic neuron expression. Development (Cambridge, England). 127: 3777-88. PMID 10934022  0.251
1994 Xu H, Federoff H, Maragos J, Parada LF, Kessler JA. Viral transduction of trkA into cultured nodose and spinal motor neurons conveys NGF responsiveness. Developmental Biology. 163: 152-61. PMID 8174770 DOI: 10.1006/Dbio.1994.1131  0.247
2003 Liebl DJ, Morris CJ, Henkemeyer M, Parada LF. mRNA expression of ephrins and Eph receptor tyrosine kinases in the neonatal and adult mouse central nervous system. Journal of Neuroscience Research. 71: 7-22. PMID 12478610 DOI: 10.1002/Jnr.10457  0.247
1991 Soppet D, Escandon E, Maragos J, Middlemas DS, Reid SW, Blair J, Burton LE, Stanton BR, Kaplan DR, Hunter T, Nikolics K, Parada LF. The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell. 65: 895-903. PMID 1645620 DOI: 10.1016/0092-8674(91)90396-G  0.247
2001 Nef S, Lush ME, Shipman TE, Parada LF. Neurotrophins are not required for normal embryonic development of olfactory neurons. Developmental Biology. 234: 80-92. PMID 11356021 DOI: 10.1006/dbio.2001.0240  0.247
2011 Le LQ, Liu C, Shipman T, Chen Z, Suter U, Parada LF. Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development. Cancer Research. 71: 4686-95. PMID 21551250 DOI: 10.1158/0008-5472.Can-10-4577  0.244
2013 Mason BL, Lobo MK, Parada LF, Lutter M. Trk B signaling in dopamine 1 receptor neurons regulates food intake and body weight. Obesity (Silver Spring, Md.). 21: 2372-6. PMID 23512795 DOI: 10.1002/oby.20382  0.242
1999 Klesse LJ, Parada LF. Trks: signal transduction and intracellular pathways. Microscopy Research and Technique. 45: 210-6. PMID 10383113 DOI: 10.1002/(SICI)1097-0029(19990515/01)45:4/5<210::AID-JEMT4>3.0.CO;2-F  0.238
1994 Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, Reid SW, Buchberg AM, Jenkins NA, Parada LF, Copeland NG. Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes & Development. 8: 1019-29. PMID 7926784 DOI: 10.1101/Gad.8.9.1019  0.237
2005 Yu TS, Dandekar M, Monteggia LM, Parada LF, Kernie SG. Temporally regulated expression of Cre recombinase in neural stem cells. Genesis (New York, N.Y. : 2000). 41: 147-53. PMID 15789426 DOI: 10.1002/Gene.20110  0.236
2012 Fassl A, Tagscherer KE, Richter J, Berriel Diaz M, Alcantara Llaguno SR, Campos B, Kopitz J, Herold-Mende C, Herzig S, Schmidt MH, Parada LF, Wiestler OD, Roth W. Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1. Oncogene. 31: 4698-708. PMID 22249262 DOI: 10.1038/onc.2011.615  0.235
1990 Klein R, Martin-Zanca D, Barbacid M, Parada LF. Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system. Development (Cambridge, England). 109: 845-50. PMID 2171894  0.234
2009 Bodempudi V, Yamoutpoor F, Pan W, Dudek AZ, Esfandyari T, Piedra M, Babovick-Vuksanovic D, Woo RA, Mautner VF, Kluwe L, Clapp DW, De Vries GH, Thomas SL, Kurtz A, Parada LF, et al. Ral overactivation in malignant peripheral nerve sheath tumors. Molecular and Cellular Biology. 29: 3964-74. PMID 19414599 DOI: 10.1128/Mcb.01153-08  0.232
2015 Zaldua N, Llavero F, Artaso A, Gálvez P, Lacerda HM, Parada LA, Zugaza JL. Rac1/p21-activated kinase pathway controls RB phosphorylation and E2F transcription factor activation in B-lymphocytes. The Febs Journal. PMID 26663827 DOI: 10.1111/febs.13617  0.232
1992 Parada LF, Tsoulfas P, Tessarollo L, Blair J, Reid SW, Soppet D. The Trk family of tyrosine kinases: receptors for NGF-related neurotrophins. Cold Spring Harbor Symposia On Quantitative Biology. 57: 43-51. PMID 1339678 DOI: 10.1101/Sqb.1992.057.01.006  0.231
2001 Gutmann DH, Wu YL, Hedrick NM, Zhu Y, Guha A, Parada LF. Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes. Human Molecular Genetics. 10: 3009-16. PMID 11751683 DOI: 10.1093/Hmg/10.26.3009  0.231
2003 Harada C, Harada T, Quah HM, Maekawa F, Yoshida K, Ohno S, Wada K, Parada LF, Tanaka K. Potential role of glial cell line-derived neurotrophic factor receptors in Müller glial cells during light-induced retinal degeneration. Neuroscience. 122: 229-35. PMID 14596863 DOI: 10.1016/S0306-4522(03)00599-2  0.231
1999 Klesse LJ, Meyers KA, Marshall CJ, Parada LF. Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells. Oncogene. 18: 2055-68. PMID 10321730 DOI: 10.1038/sj.onc.1202524  0.231
1989 Klein R, Parada LF, Coulier F, Barbacid M. trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development. The Embo Journal. 8: 3701-9. PMID 2555172  0.23
2020 Xie XP, Laks DR, Sun D, Poran A, Laughney AM, Wang Z, Sam J, Belenguer G, Fariñas I, Elemento O, Zhou X, Parada LF. High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging. Proceedings of the National Academy of Sciences of the United States of America. PMID 33229571 DOI: 10.1073/pnas.2014389117  0.23
2016 Alcantara Llaguno SR, Xie X, Parada LF. Cell of Origin and Cancer Stem Cells in Tumor Suppressor Mouse Models of Glioblastoma. Cold Spring Harbor Symposia On Quantitative Biology. PMID 27815542 DOI: 10.1101/sqb.2016.81.030973  0.227
2008 Llaguno SA, Chen J, Kwon CH, Parada LF. Neural and cancer stem cells in tumor suppressor mouse models of malignant astrocytoma. Cold Spring Harbor Symposia On Quantitative Biology. 73: 421-6. PMID 19022744 DOI: 10.1101/Sqb.2008.73.005  0.227
1991 Kaplan DR, Martin-Zanca D, Parada LF. Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF. Nature. 350: 158-60. PMID 1706478 DOI: 10.1038/350158a0  0.225
2009 Clapp DW, Yang F, Ingram DA, Robertson KA, Hutchins GD, Parada LF. Mast Cells and Tumor Progression. Blood. 114: SCI-33-SCI-33. DOI: 10.1182/Blood.V114.22.Sci-33.Sci-33  0.224
1997 Dechant G, Tsoulfas P, Parada LF, Barde YA. The neurotrophin receptor p75 binds neurotrophin-3 on sympathetic neurons with high affinity and specificity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5281-7. PMID 9204912 DOI: 10.1523/Jneurosci.17-14-05281.1997  0.224
2000 Gonzalez-Zulueta M, Feldman AB, Klesse LJ, Kalb RG, Dillman JF, Parada LF, Dawson TM, Dawson VL. Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 97: 436-41. PMID 10618436 DOI: 10.1073/Pnas.97.1.436  0.222
2009 Le LQ, Shipman T, Burns DK, Parada LF. Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas. Cell Stem Cell. 4: 453-63. PMID 19427294 DOI: 10.1016/J.Stem.2009.03.017  0.221
2011 Lim SK, Llaguno SR, McKay RM, Parada LF. Glioblastoma multiforme: a perspective on recent findings in human cancer and mouse models. Bmb Reports. 44: 158-64. PMID 21429292 DOI: 10.5483/BMBRep.2011.44.3.158  0.22
2007 Ogawa S, Kwon CH, Zhou J, Koovakkattu D, Parada LF, Sinton CM. A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice. Brain Research. 1168: 112-23. PMID 17706614 DOI: 10.1016/J.Brainres.2007.06.074  0.219
2013 Biddlestone-Thorpe L, Sajjad M, Rosenberg E, Beckta JM, Valerie NC, Tokarz M, Adams BR, Wagner AF, Khalil A, Gilfor D, Golding SE, Deb S, Temesi DG, Lau A, O'Connor MJ, ... ... Parada LF, et al. ATM kinase inhibition preferentially sensitizes p53-mutant glioma to ionizing radiation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3189-200. PMID 23620409 DOI: 10.1158/1078-0432.Ccr-12-3408  0.218
2022 Xie XP, Laks DR, Sun D, Ganbold M, Wang Z, Pedraza AM, Bale T, Tabar V, Brennan C, Zhou X, Parada LF. Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy. Developmental Cell. 57: 32-46.e8. PMID 35016005 DOI: 10.1016/j.devcel.2021.12.007  0.215
1991 Keshet E, Lyman SD, Williams DE, Anderson DM, Jenkins NA, Copeland NG, Parada LF. Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development. The Embo Journal. 10: 2425-35. PMID 1714375 DOI: 10.1002/J.1460-2075.1991.Tb07782.X  0.215
1992 Stanton BR, Parada LF. The N-myc proto-oncogene: developmental expression and in vivo site-directed mutagenesis. Brain Pathology (Zurich, Switzerland). 2: 71-83. PMID 1341949  0.214
2001 Schonhoff CM, Bulseco DA, Brancho DM, Parada LF, Ross AH. The Ras-ERK pathway is required for the induction of neuronal nitric oxide synthase in differentiating PC12 cells. Journal of Neurochemistry. 78: 631-9. PMID 11483666 DOI: 10.1046/J.1471-4159.2001.00432.X  0.214
2018 Vega-Benedetti AF, Saucedo CN, Zavattari P, Vanni R, Royo F, Llavero F, Zugaza JL, Parada LA. gene function during hepatoma cells proliferation. Oncotarget. 9: 32775-32794. PMID 30214684 DOI: 10.18632/oncotarget.25996  0.21
2002 Bajenaru ML, Zhu Y, Hedrick NM, Donahoe J, Parada LF, Gutmann DH. Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. Molecular and Cellular Biology. 22: 5100-13. PMID 12077339 DOI: 10.1128/Mcb.22.14.5100-5113.2002  0.21
2019 Llavero F, Luque Montoro M, Arrazola Sastre A, Fernández-Moreno D, Lacerda HM, Parada LA, Lucia A, Zugaza JL. Epidermal growth factor receptor controls glycogen phosphorylase in T cells through small GTPases of the RAS family. The Journal of Biological Chemistry. PMID 30647127 DOI: 10.1074/jbc.RA118.005997  0.21
2009 Alcantara Llaguno SR, Chen J, Parada LF. Signaling in malignant astrocytomas: role of neural stem cells and its therapeutic implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 7124-9. PMID 19934302 DOI: 10.1158/1078-0432.CCR-09-0433  0.209
2011 Alcantara Llaguno SR, Chen Y, McKay RM, Parada LF. Stem cells in brain tumor development. Current Topics in Developmental Biology. 94: 15-44. PMID 21295683 DOI: 10.1016/B978-0-12-380916-2.00002-4  0.209
2007 Le LQ, Parada LF. Tumor microenvironment and neurofibromatosis type I: connecting the GAPs. Oncogene. 26: 4609-16. PMID 17297459 DOI: 10.1038/Sj.Onc.1210261  0.208
1994 Urfer R, Tsoulfas P, Soppet D, Escandón E, Parada LF, Presta LG. The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin. The Embo Journal. 13: 5896-909. PMID 7529173  0.208
1996 Tsoulfas P, Stephens RM, Kaplan DR, Parada LF. TrkC isoforms with inserts in the kinase domain show impaired signaling responses. The Journal of Biological Chemistry. 271: 5691-7. PMID 8621434 DOI: 10.1074/Jbc.271.10.5691  0.207
2016 Llaguno SR, Parada LF. Cell of origin of glioma: biological and clinical implications. British Journal of Cancer. PMID 27832665 DOI: 10.1038/bjc.2016.354  0.207
2009 Zhou J, Brugarolas J, Parada LF. Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1. Human Molecular Genetics. 18: 4428-41. PMID 19692352 DOI: 10.1093/Hmg/Ddp398  0.207
2006 Malkovska I, Kernie SG, Parada LF. Differential expression of the four untranslated BDNF exons in the adult mouse brain. Journal of Neuroscience Research. 83: 211-21. PMID 16385578 DOI: 10.1002/Jnr.20728  0.205
2005 Shi J, Parada LF, Kernie SG. Bax limits adult neural stem cell persistence through caspase and IP3 receptor activation. Cell Death and Differentiation. 12: 1601-12. PMID 15947791 DOI: 10.1038/Sj.Cdd.4401676  0.205
2008 Joseph NM, Mosher JT, Buchstaller J, Snider P, McKeever PE, Lim M, Conway SJ, Parada LF, Zhu Y, Morrison SJ. The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer Cell. 13: 129-40. PMID 18242513 DOI: 10.1016/J.Ccr.2008.01.003  0.204
2009 Gregorian C, Nakashima J, Dry SM, Nghiemphu PL, Smith KB, Ao Y, Dang J, Lawson G, Mellinghoff IK, Mischel PS, Phelps M, Parada LF, Liu X, Sofroniew MV, Eilber FC, et al. PTEN dosage is essential for neurofibroma development and malignant transformation. Proceedings of the National Academy of Sciences of the United States of America. 106: 19479-84. PMID 19846776 DOI: 10.1073/Pnas.0910398106  0.201
2013 Manterola L, Hernando-Rodríguez M, Ruiz A, Apraiz A, Arrizabalaga O, Vellón L, Alberdi E, Cavaliere F, Lacerda HM, Jimenez S, Parada LA, Matute C, Zugaza JL. 1-42 β-amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death. Translational Psychiatry. 3: e219. PMID 23340502 DOI: 10.1038/tp.2012.147  0.201
2005 Lush ME, Ma L, Parada LF. TrkB signaling regulates the developmental maturation of the somatosensory cortex. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 23: 523-36. PMID 16009525 DOI: 10.1016/j.ijdevneu.2005.04.003  0.201
2008 Parrinello S, Noon LA, Harrisingh MC, Wingfield Digby P, Rosenberg LH, Cremona CA, Echave P, Flanagan AM, Parada LF, Lloyd AC. NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F. Genes & Development. 22: 3335-48. PMID 19056885 DOI: 10.1101/Gad.490608  0.2
2006 Kwon B, Alcantara S, Chen J, Parada L. [S37]: Mouse models of progenitor cell based gliomas in mice International Journal of Developmental Neuroscience. 24: 487-488. DOI: 10.1016/j.ijdevneu.2006.09.044  0.2
2007 Kim A, Morgan K, Hasz DE, Wiesner SM, Lauchle JO, Geurts JL, Diers MD, Le DT, Kogan SC, Parada LF, Shannon K, Largaespada DA. Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice. Blood. 109: 1687-91. PMID 17090653 DOI: 10.1182/Blood-2006-05-025395  0.199
2008 Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A. Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes. The American Journal of Pathology. 173: 1861-72. PMID 18988803 DOI: 10.2353/ajpath.2008.080376  0.198
2012 Zhou J, Parada LF. PTEN signaling in autism spectrum disorders. Current Opinion in Neurobiology. 22: 873-9. PMID 22664040 DOI: 10.1016/j.conb.2012.05.004  0.197
1991 Loeb DM, Maragos J, Martin-Zanca D, Chao MV, Parada LF, Greene LA. The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines. Cell. 66: 961-6. PMID 1653650 DOI: 10.1016/0092-8674(91)90441-Z  0.197
2006 Yang FC, Chen S, Clegg T, Li X, Morgan T, Estwick SA, Yuan J, Khalaf W, Burgin S, Travers J, Parada LF, Ingram DA, Clapp DW. Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. Human Molecular Genetics. 15: 2421-37. PMID 16835260 DOI: 10.1093/hmg/ddl165  0.196
1999 Vogel KS, Klesse LJ, Velasco-Miguel S, Meyers K, Rushing EJ, Parada LF. Mouse tumor model for neurofibromatosis type 1. Science (New York, N.Y.). 286: 2176-9. PMID 10591653  0.196
2005 Parada LF, Kwon CH, Zhu Y. Modeling neurofibromatosis type 1 tumors in the mouse for therapeutic intervention. Cold Spring Harbor Symposia On Quantitative Biology. 70: 173-6. PMID 16869751 DOI: 10.1101/sqb.2005.70.025  0.196
2003 Nef S, Verma-Kurvari S, Merenmies J, Vassalli JD, Efstratiadis A, Accili D, Parada LF. Testis determination requires insulin receptor family function in mice. Nature. 426: 291-5. PMID 14628051 DOI: 10.1038/Nature02059  0.195
2023 Chipman ME, Wang Z, Sun D, Pedraza AM, Bale TA, Parada LF. Tumor progression is independent of tumor-associated macrophages in cell lineage-based mouse models of glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 120: e2222084120. PMID 37040416 DOI: 10.1073/pnas.2222084120  0.194
2002 Zhu Y, Ghosh P, Charnay P, Burns DK, Parada LF. Neurofibromas in NF1: Schwann cell origin and role of tumor environment. Science (New York, N.Y.). 296: 920-2. PMID 11988578 DOI: 10.1126/Science.1068452  0.194
1999 Kelly-Spratt KS, Klesse LJ, Merenmies J, Parada LF. A TrkB/insulin receptor-related receptor chimeric receptor induces PC12 cell differentiation and exhibits prolonged activation of mitogen-activated protein kinase. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 10: 805-12. PMID 10616905  0.193
1992 Hempstead BL, Rabin SJ, Kaplan L, Reid S, Parada LF, Kaplan DR. Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation. Neuron. 9: 883-96. PMID 1384575 DOI: 10.1016/0896-6273(92)90241-5  0.192
2006 Wagner E, Luo T, Sakai Y, Parada LF, Dräger UC. Retinoic acid delineates the topography of neuronal plasticity in postnatal cerebral cortex. The European Journal of Neuroscience. 24: 329-40. PMID 16836633 DOI: 10.1111/j.1460-9568.2006.04934.x  0.192
1992 Berg MM, Sternberg DW, Parada LF, Chao MV. K-252a inhibits nerve growth factor-induced trk proto-oncogene tyrosine phosphorylation and kinase activity. The Journal of Biological Chemistry. 267: 13-6. PMID 1730579  0.191
1995 Urfer R, Tsoulfas P, O'Connell L, Shelton DL, Parada LF, Presta LG. An immunoglobulin-like domain determines the specificity of neurotrophin receptors. The Embo Journal. 14: 2795-805. PMID 7796806  0.191
2006 Harada C, Harada T, Nakamura K, Sakai Y, Tanaka K, Parada LF. Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye. Developmental Biology. 290: 57-65. PMID 16343477 DOI: 10.1016/j.ydbio.2005.08.051  0.191
1998 Zhu Y, Richardson JA, Parada LF, Graff JM. Smad3 mutant mice develop metastatic colorectal cancer. Cell. 94: 703-14. PMID 9753318 DOI: 10.1016/S0092-8674(00)81730-4  0.19
2002 Harada T, Harada C, Kohsaka S, Wada E, Yoshida K, Ohno S, Mamada H, Tanaka K, Parada LF, Wada K. Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9228-36. PMID 12417648 DOI: 10.1523/Jneurosci.22-21-09228.2002  0.19
2007 Lauchle JO, Le DT, Kim D, Akagi K, Gorman MF, Tran M, Sebolt-Leopold J, Wolff L, Parada LF, Jenkins N, Copeland N, Shannon KM. Mutations That Cooperate with Nf1 Inactivation in Leukemogenesis Influence Therapeutic Response to MEK Inhibition. Blood. 110: 594-594. DOI: 10.1182/Blood.V110.11.594.594  0.189
2014 Chau V, Lim SK, Mo W, Liu C, Patel AJ, McKay RM, Wei S, Posner BA, De Brabander JK, Williams NS, Parada LF, Le LQ. Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors. Cancer Research. 74: 586-97. PMID 24285727 DOI: 10.1158/0008-5472.Can-13-1934  0.189
2004 Verma-Kurvari S, Parada LF. Identification of tyrosine kinases expressed in the male mouse gubernaculum during development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 230: 660-5. PMID 15254900 DOI: 10.1002/dvdy.20090  0.189
1995 Donovan MJ, Miranda RC, Kraemer R, McCaffrey TA, Tessarollo L, Mahadeo D, Sharif S, Kaplan DR, Tsoulfas P, Parada L. Neurotrophin and neurotrophin receptors in vascular smooth muscle cells. Regulation of expression in response to injury. The American Journal of Pathology. 147: 309-24. PMID 7639328  0.189
2009 Llaguno SA, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model (DOI:10.1016/j.ccr.2008.12.006) Cancer Cell. 15: 240. DOI: 10.1016/J.Ccr.2009.02.008  0.189
2003 Gitler AD, Zhu Y, Ismat FA, Lu MM, Yamauchi Y, Parada LF, Epstein JA. Nf1 has an essential role in endothelial cells. Nature Genetics. 33: 75-9. PMID 12469121 DOI: 10.1038/Ng1059  0.188
2006 Bingham NC, Verma-Kurvari S, Parada LF, Parker KL. Development of a steroidogenic factor 1/Cre transgenic mouse line. Genesis (New York, N.Y. : 2000). 44: 419-24. PMID 16937416 DOI: 10.1002/dvg.20231  0.187
2014 Shi Y, Lim SK, Parada LF. The soft underbelly of tumor cells. Cell Research. 24: 910-1. PMID 24874955 DOI: 10.1038/cr.2014.72  0.186
1994 Donovan MJ, Hempstead B, Huber LJ, Kaplan D, Tsoulfas P, Chao M, Parada L, Schofield D. Identification of the neurotrophin receptors p75 and trk in a series of Wilms' tumors. The American Journal of Pathology. 145: 792-801. PMID 7943171  0.186
2023 Nguyen TP, Wang W, Sternisha AC, Corley CD, Wang HL, Wang X, Ortiz F, Lim SK, Abdullah KG, Parada LF, Williams NS, McBrayer SK, McDonald JG, De Brabander JK, Nijhawan D. Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by inducing 24(S),25-epoxycholesterol production. Cell Chemical Biology. PMID 36758549 DOI: 10.1016/j.chembiol.2023.01.005  0.186
2015 Lubeck BA, Lapinski PE, Oliver JA, Ksionda O, Parada LF, Zhu Y, Maillard I, Chiang M, Roose J, King PD. Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia. Journal of Immunology (Baltimore, Md. : 1950). 195: 31-5. PMID 26002977 DOI: 10.4049/Jimmunol.1402639  0.186
2013 Oliver JA, Lapinski PE, Lubeck BA, Turner JS, Parada LF, Zhu Y, King PD. The Ras GTPase-activating protein neurofibromin 1 promotes the positive selection of thymocytes. Molecular Immunology. 55: 292-302. PMID 23522726 DOI: 10.1016/j.molimm.2013.03.005  0.185
2012 Chen J, McKay RM, Parada LF. Malignant glioma: lessons from genomics, mouse models, and stem cells. Cell. 149: 36-47. PMID 22464322 DOI: 10.1016/j.cell.2012.03.009  0.185
2012 Kim TH, Song J, Alcantara Llaguno SR, Murnan E, Liyanarachchi S, Palanichamy K, Yi JY, Viapiano MS, Nakano I, Yoon SO, Wu H, Parada LF, Kwon CH. Suppression of peroxiredoxin 4 in glioblastoma cells increases apoptosis and reduces tumor growth. Plos One. 7: e42818. PMID 22916164 DOI: 10.1371/Journal.Pone.0042818  0.183
2005 Zhu Y, Harada T, Liu L, Lush ME, Guignard F, Harada C, Burns DK, Bajenaru ML, Gutmann DH, Parada LF. Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation. Development (Cambridge, England). 132: 5577-88. PMID 16314489 DOI: 10.1242/Dev.02162  0.182
1994 Averbuch-Heller L, Pruginin M, Kahane N, Tsoulfas P, Parada L, Rosenthal A, Kalcheim C. Neurotrophin 3 stimulates the differentiation of motoneurons from avian neural tube progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 3247-51. PMID 8159733 DOI: 10.1073/Pnas.91.8.3247  0.182
2022 Nishijima E, Honda S, Kitamura Y, Namekata K, Kimura A, Guo X, Azuchi Y, Harada C, Murakami A, Matsuda A, Nakano T, Parada LF, Harada T. Vision protection and robust axon regeneration in glaucoma models by membrane-associated Trk receptors. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 36463402 DOI: 10.1016/j.ymthe.2022.11.018  0.181
2007 Kolanczyk M, Kossler N, Kühnisch J, Lavitas L, Stricker S, Wilkening U, Manjubala I, Fratzl P, Spörle R, Herrmann BG, Parada LF, Kornak U, Mundlos S. Multiple roles for neurofibromin in skeletal development and growth. Human Molecular Genetics. 16: 874-86. PMID 17317783 DOI: 10.1093/Hmg/Ddm032  0.18
2005 Harada C, Harada T, Quah HM, Namekata K, Yoshida K, Ohno S, Tanaka K, Parada LF. Role of neurotrophin-4/5 in neural cell death during retinal development and ischemic retinal injury in vivo. Investigative Ophthalmology & Visual Science. 46: 669-73. PMID 15671298 DOI: 10.1167/iovs.04-0826  0.178
1991 Kaplan DR, Hempstead BL, Martin-Zanca D, Chao MV, Parada LF. The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science (New York, N.Y.). 252: 554-8. PMID 1850549 DOI: 10.1126/Science.1850549  0.178
2002 Li H, Velasco-Miguel S, Vass WC, Parada LF, DeClue JE. Epidermal growth factor receptor signaling pathways are associated with tumorigenesis in the Nf1:p53 mouse tumor model. Cancer Research. 62: 4507-13. PMID 12154062  0.178
2010 Martínez-López N, Varela-Rey M, Fernández-Ramos D, Woodhoo A, Vázquez-Chantada M, Embade N, Espinosa-Hevia L, Bustamante FJ, Parada LA, Rodriguez MS, Lu SC, Mato JM, Martínez-Chantar ML. Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steatohepatitis. Hepatology (Baltimore, Md.). 52: 1621-31. PMID 20815019 DOI: 10.1002/hep.23860  0.178
1992 Stanton BR, Perkins AS, Tessarollo L, Sassoon DA, Parada LF. Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes & Development. 6: 2235-47. PMID 1459449  0.177
2011 Hambardzumyan D, Parada LF, Holland EC, Charest A. Genetic modeling of gliomas in mice: new tools to tackle old problems. Glia. 59: 1155-68. PMID 21305617 DOI: 10.1002/glia.21142  0.177
1993 Tsoulfas P, Soppet D, Escandon E, Tessarollo L, Mendoza-Ramirez JL, Rosenthal A, Nikolics K, Parada LF. The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells. Neuron. 10: 975-90. PMID 8494648 DOI: 10.1016/0896-6273(93)90212-A  0.177
2012 Borrego-Diaz E, Terai K, Lialyte K, Wise AL, Esfandyari T, Behbod F, Mautner VF, Spyra M, Taylor S, Parada LF, Upadhyaya M, Farassati F. Overactivation of Ras signaling pathway in CD133+ MPNST cells. Journal of Neuro-Oncology. 108: 423-34. PMID 22484909 DOI: 10.1007/S11060-012-0852-1  0.176
2007 Lei L, Parada LF. Transcriptional regulation of Trk family neurotrophin receptors. Cellular and Molecular Life Sciences : Cmls. 64: 522-32. PMID 17192812 DOI: 10.1007/s00018-006-6328-8  0.174
2017 Parada LF, Dirks PB, Wechsler-Reya RJ. Brain Tumor Stem Cells Remain in Play. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017739540. PMID 28640710 DOI: 10.1200/Jco.2017.73.9540  0.174
2015 Zong H, Parada LF, Baker SJ. Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harbor Perspectives in Biology. 7. PMID 25635044 DOI: 10.1101/Cshperspect.A020610  0.173
2013 Ribeiro S, Napoli I, White IJ, Parrinello S, Flanagan AM, Suter U, Parada LF, Lloyd AC. Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve. Cell Reports. 5: 126-36. PMID 24075988 DOI: 10.1016/J.Celrep.2013.08.033  0.171
2002 Ma L, Harada T, Harada C, Romero M, Hebert JM, McConnell SK, Parada LF. Neurotrophin-3 is required for appropriate establishment of thalamocortical connections. Neuron. 36: 623-34. PMID 12441052 DOI: 10.1016/S0896-6273(02)01021-8  0.171
2003 Bajenaru ML, Hernandez MR, Perry A, Zhu Y, Parada LF, Garbow JR, Gutmann DH. Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. Cancer Research. 63: 8573-7. PMID 14695164  0.17
2013 Nalepa G, Barnholtz-Sloan J, Enzor R, Dey D, He Y, Gehlhausen JR, Lehmann AS, Park SJ, Yang Y, Yang X, Chen S, Guan X, Chen Y, Renbarger J, Yang FC, ... Parada LF, et al. The tumor suppressor CDKN3 controls mitosis. The Journal of Cell Biology. 201: 997-1012. PMID 23775190 DOI: 10.1083/Jcb.201205125  0.169
2001 Liebl DJ, Huang W, Young W, Parada LF. Regulation of Trk receptors following contusion of the rat spinal cord. Experimental Neurology. 167: 15-26. PMID 11161589 DOI: 10.1006/Exnr.2000.7548  0.169
1997 Bates CM, Merenmies JM, Kelly-Spratt KS, Parada LF. Insulin receptor-related receptor expression in non-A intercalated cells in the kidney. Kidney International. 52: 674-81. PMID 9291186  0.169
2010 Namekata K, Harada C, Taya C, Guo X, Kimura H, Parada LF, Harada T. Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex. Proceedings of the National Academy of Sciences of the United States of America. 107: 7586-91. PMID 20368433 DOI: 10.1073/pnas.0914514107  0.168
2007 Cai J, Chen Y, Cai WH, Hurlock EC, Wu H, Kernie SG, Parada LF, Lu QR. A crucial role for Olig2 in white matter astrocyte development. Development (Cambridge, England). 134: 1887-99. PMID 17428828 DOI: 10.1242/Dev.02847  0.168
1992 Tessarollo L, Nagarajan L, Parada LF. c-ros: the vertebrate homolog of the sevenless tyrosine kinase receptor is tightly regulated during organogenesis in mouse embryonic development. Development (Cambridge, England). 115: 11-20. PMID 1638975  0.167
2021 Qin Y, Wong B, Zhong L, Geng F, Parada LF, Wen D. Generation of Sex-Reversed Female Clonal Mice via CRISPR-Cas9-Mediated Y Chromosome Deletion in Male Embryonic Stem Cells. The Crispr Journal. PMID 33567216 DOI: 10.1089/crispr.2020.0074  0.166
1991 Vetter ML, Martin-Zanca D, Parada LF, Bishop JM, Kaplan DR. Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene. Proceedings of the National Academy of Sciences of the United States of America. 88: 5650-4. PMID 1712104  0.166
2012 Buchstaller J, Clapp DW, Parada LF, Zhu Y. Cell of origin and the contribution of microenvironment in NF1 tumorigenesis and therapeutic implications Neurofibromatosis Type 1: Molecular and Cellular Biology. 2147483647: 549-568. DOI: 10.1007/978-3-642-32864-0_36  0.163
2000 Kernie SG, Parada LF. The molecular basis for understanding neurotrophins and their relevance to neurologic disease. Archives of Neurology. 57: 654-7. PMID 10815130 DOI: 10.1001/Archneur.57.5.654  0.162
2009 Lin L, Chen J, Richardson JA, Parada LF. Mice lacking neurofibromin develop gastric hyperplasia. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G751-61. PMID 19661150 DOI: 10.1152/ajpgi.00007.2009  0.161
2021 Alcantara Llaguno S, Parada LF. Cancer stem cells in gliomas: evolving concepts and therapeutic implications. Current Opinion in Neurology. 34: 868-874. PMID 34581301 DOI: 10.1097/WCO.0000000000000994  0.16
2001 Yokoyama N, Romero MI, Cowan CA, Galvan P, Helmbacher F, Charnay P, Parada LF, Henkemeyer M. Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline. Neuron. 29: 85-97. PMID 11182083 DOI: 10.1016/S0896-6273(01)00182-9  0.157
2015 Llavero F, Urzelai B, Osinalde N, Gálvez P, Lacerda HM, Parada LA, Zugaza JL. Guanine nucleotide exchange factor αPIX leads to activation of the Rac 1 GTPase/glycogen phosphorylase pathway in interleukin (IL)-2-stimulated T cells. The Journal of Biological Chemistry. 290: 9171-82. PMID 25694429 DOI: 10.1074/jbc.M114.608414  0.156
2001 Kubota Y, Nef S, Farmer PJ, Temelcos C, Parada LF, Hutson JM. Leydig insulin-like hormone, gubernacular development and testicular descent. The Journal of Urology. 165: 1673-5. PMID 11342953  0.154
2001 Kernie SG, Erwin TM, Parada LF. Brain remodeling due to neuronal and astrocytic proliferation after controlled cortical injury in mice. Journal of Neuroscience Research. 66: 317-26. PMID 11746349 DOI: 10.1002/Jnr.10013  0.152
1995 Slaugenhaupt SA, Blumenfeld A, Liebert CB, Mull J, Lucente DE, Monahan M, Breakefield XO, Maayan C, Parada L, Axelrod FB. The human gene for neurotrophic tyrosine kinase receptor type 2 (NTRK2) is located on chromosome 9 but is not the familial dysautonomia gene. Genomics. 25: 730-2. PMID 7759111 DOI: 10.1016/0888-7543(95)80019-I  0.151
1991 Nebreda AR, Martin-Zanca D, Kaplan DR, Parada LF, Santos E. Induction by NGF of meiotic maturation of Xenopus oocytes expressing the trk proto-oncogene product. Science (New York, N.Y.). 252: 558-61. PMID 1850550  0.15
1993 Moens CB, Stanton BR, Parada LF, Rossant J. Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus. Development (Cambridge, England). 119: 485-99. PMID 8287798  0.149
1995 Offenhäuser N, Böhm-Matthaei R, Tsoulfas P, Parada L, Meyer M. Developmental regulation of full-length trkC in the rat sciatic nerve. The European Journal of Neuroscience. 7: 917-25. PMID 7613627 DOI: 10.1111/J.1460-9568.1995.Tb01079.X  0.148
1990 Stanton BR, Reid SW, Parada LF. Germ line transmission of an inactive N-myc allele generated by homologous recombination in mouse embryonic stem cells. Molecular and Cellular Biology. 10: 6755-8. PMID 1701023  0.146
2018 Sun D, Sait SF, Wang Z, Parada L. NFM-05. CANCER STEM CELLS PROMOTE RELAPSE IN NEUROFIBROMATOSIS TYPE 1 ASSOCIATED MALIGNANT PERIPHERAL NERVE SHEATH TUMORS Neuro-Oncology. 20: i143-i143. DOI: 10.1093/neuonc/noy059.513  0.145
2010 Vellón L, Royo F, Matthiesen R, Torres-Fuenzalida J, Lorenti A, Parada LA. Functional blockade of α5β1 integrin induces scattering and genomic landscape remodeling of hepatic progenitor cells. Bmc Cell Biology. 11: 81. PMID 20958983 DOI: 10.1186/1471-2121-11-81  0.144
1999 Nef S, Parada LF. Cryptorchidism in mice mutant for Insl3. Nature Genetics. 22: 295-9. PMID 10391220 DOI: 10.1038/10364  0.143
1990 Klein R, Conway D, Parada LF, Barbacid M. The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain. Cell. 61: 647-56. PMID 2160854 DOI: 10.1016/0092-8674(90)90476-U  0.142
2005 Verma-Kurvari S, Nef S, Parada LF. Hormonal regulation of male reproductive tract development. Annals of the New York Academy of Sciences. 1061: 1-8. PMID 16467252 DOI: 10.1196/annals.1336.002  0.142
2009 Royo F, Paz N, Espinosa L, McQueen PG, Vellón L, Parada LA. Spatial link between nucleoli and expression of the Zac1 gene. Chromosoma. 118: 711-22. PMID 19649645 DOI: 10.1007/s00412-009-0229-1  0.14
2016 Llavero F, Artaso A, Lacerda HM, Parada LA, Zugaza JL. Lck/PLCγ control migration and proliferation of interleukin (IL)-2-stimulated T cells via the Rac1 GTPase/glycogen phosphorylase pathway. Cellular Signalling. 28: 1713-1724. PMID 27519475 DOI: 10.1016/j.cellsig.2016.07.014  0.14
1991 Hempstead BL, Martin-Zanca D, Kaplan DR, Parada LF, Chao MV. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature. 350: 678-83. PMID 1850821 DOI: 10.1038/350678A0  0.14
2006 Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metabolism. 4: 441-51. PMID 17141628 DOI: 10.1016/J.Cmet.2006.10.010  0.137
1994 Shikata A, Sugimoto T, Hosoi H, Sotozono Y, Shikata T, Sawada T, Parada LF. Increased expression of trk proto-oncogene by gamma-interferon in human neuroblastoma cell lines. Japanese Journal of Cancer Research : Gann. 85: 122-6. PMID 8144393 DOI: 10.1111/j.1349-7006.1994.tb02070.x  0.135
2002 Zhu Y, Parada LF. The molecular and genetic basis of neurological tumours. Nature Reviews. Cancer. 2: 616-26. PMID 12154354 DOI: 10.1038/nrc866  0.134
1996 Nelson CE, Morgan BA, Burke AC, Laufer E, DiMambro E, Murtaugh LC, Gonzales E, Tessarollo L, Parada LF, Tabin C. Analysis of Hox gene expression in the chick limb bud. Development (Cambridge, England). 122: 1449-66. PMID 8625833  0.133
2012 Alanne MH, Siljamäki E, Peltonen S, Väänänen K, Windle JJ, Parada LF, Määttä JA, Peltonen J. Phenotypic characterization of transgenic mice harboring Nf1+/- or Nf1-/- osteoclasts in otherwise Nf1+/+ background. Journal of Cellular Biochemistry. 113: 2136-46. PMID 22307743 DOI: 10.1002/Jcb.24088  0.133
2010 Le LQ, Shipman T, Burns DK, Parada LF. Stem cell origin and microenvironment contribution for NF1-associated neurofibromas Ifmbe Proceedings. 27: 219-222. DOI: 10.1007/978-3-642-12020-6-55  0.131
2015 Rauen KA, Huson SM, Burkitt-Wright E, Evans DG, Farschtschi S, Ferner RE, Gutmann DH, Hanemann CO, Kerr B, Legius E, Parada LF, Patton M, Peltonen J, Ratner N, Riccardi VM, et al. Recent developments in neurofibromatoses and RASopathies: management, diagnosis and current and future therapeutic avenues. American Journal of Medical Genetics. Part A. 167: 1-10. PMID 25393061 DOI: 10.1002/Ajmg.A.36793  0.13
2001 Kitamura T, Kido Y, Nef S, Merenmies J, Parada LF, Accili D. Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor. Molecular and Cellular Biology. 21: 5624-30. PMID 11463843 DOI: 10.1128/Mcb.21.16.5624-5630.2001  0.13
2002 Nguyen MT, Showalter PR, Timmons CF, Nef S, Parada LF, Baker LA. Effects of orchiopexy on congenitally cryptorchid insulin-3 knockout mice. The Journal of Urology. 168: 1779-83; discussion . PMID 12352358 DOI: 10.1097/01.ju.0000028337.05764.e9  0.129
2009 Pitetti JL, Torre D, Conne B, Papaioannou MD, Cederroth CR, Xuan S, Kahn R, Parada LF, Vassalli JD, Efstratiadis A, Nef S. Insulin receptor and IGF1R are not required for oocyte growth, differentiation, and maturation in mice. Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation. 3: 264-72. PMID 19851056 DOI: 10.1159/000252813  0.128
1997 Merenmies J, Parada LF, Henkemeyer M. Receptor tyrosine kinase signaling in vascular development. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 8: 3-10. PMID 8993829  0.128
2003 Roix JJ, McQueen PG, Munson PJ, Parada LA, Misteli T. Spatial proximity of translocation-prone gene loci in human lymphomas. Nature Genetics. 34: 287-91. PMID 12808455 DOI: 10.1038/Ng1177  0.128
2016 Vega-Benedetti AF, Saucedo C, Zavattari P, Vanni R, Zugaza JL, Parada LA. PLAGL1: an important player in diverse pathological processes. Journal of Applied Genetics. PMID 27311313 DOI: 10.1007/s13353-016-0355-4  0.127
2000 Bates CM, Kharzai S, Erwin T, Rossant J, Parada LF. Role of N-myc in the developing mouse kidney. Developmental Biology. 222: 317-25. PMID 10837121 DOI: 10.1006/Dbio.2000.9716  0.126
2004 Kim SH, McQueen PG, Lichtman MK, Shevach EM, Parada LA, Misteli T. Spatial genome organization during T-cell differentiation. Cytogenetic and Genome Research. 105: 292-301. PMID 15237218 DOI: 10.1159/000078201  0.126
2006 Dissen GA, Garcia-Rudaz C, Tapia V, Parada LF, Hsu SY, Ojeda SR. Expression of the insulin receptor-related receptor is induced by the preovulatory surge of luteinizing hormone in thecal-interstitial cells of the rat ovary. Endocrinology. 147: 155-65. PMID 16195402 DOI: 10.1210/en.2005-0386  0.126
2005 Benson MD, Romero MI, Lush ME, Lu QR, Henkemeyer M, Parada LF. Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 102: 10694-9. PMID 16020529 DOI: 10.1073/Pnas.0504021102  0.123
2002 Baker LA, Nef S, Nguyen MT, Stapleton R, Nordenskjold A, Pohl H, Parada LF. The insulin-3 gene: lack of a genetic basis for human cryptorchidism. The Journal of Urology. 167: 2534-7. PMID 11992081  0.121
2015 Paz N, Felipe-Blanco I, Royo F, Zabala A, Guerra-Merino I, García-Orad Á, Zugaza JL, Parada LA. Expression of the DYRK1A gene correlates with its 3D positioning in the interphase nucleus of Down syndrome cells. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 23: 285-98. PMID 25645734 DOI: 10.1007/s10577-015-9467-7  0.12
2008 Cui Y, Costa RM, Murphy GG, Elgersma Y, Zhu Y, Gutmann DH, Parada LF, Mody I, Silva AJ. Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell. 135: 549-60. PMID 18984165 DOI: 10.1016/J.Cell.2008.09.060  0.117
2015 Kwon CH, Burns DK, Parada LF. Brain tumors Molecular Oncology: Causes of Cancer and Targets For Treatment. 641-651. DOI: 10.1017/CBO9781139046947.058  0.116
2006 Martínez-Chantar ML, Vázquez-Chantada M, Garnacho M, Latasa MU, Varela-Rey M, Dotor J, Santamaria M, Martínez-Cruz LA, Parada LA, Lu SC, Mato JM. S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase. Gastroenterology. 131: 223-32. PMID 16831604 DOI: 10.1053/j.gastro.2006.04.019  0.115
1997 Bates CM, Merenmies JM, Parada LF. INSULIN RECEPTOR- RELATED RECEPTOR IS EXPRESSED IN NON-A INTERCALATED CELLS IN THE MOUSE KIDNEY † 1640 Pediatric Research. 41: 276-276. DOI: 10.1203/00006450-199704001-01659  0.114
2019 Rauen KA, Alsaegh A, Ben-Shachar S, Berman Y, Blakeley J, Cordeiro I, Elgersma Y, Evans DG, Fisher MJ, Frayling IM, George J, Huson SM, Kerr B, Khire U, Korf B, ... ... Parada LF, et al. First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and advances of new therapeutics. American Journal of Medical Genetics. Part A. PMID 30908877 DOI: 10.1002/Ajmg.A.61125  0.114
2021 Nagle VL, Henry KE, Hertz CAJ, Graham MS, Campos C, Parada LF, Pandit-Taskar N, Schietinger A, Mellinghoff IK, Lewis JS. Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [Cu]Cu-NOTA-anti-CD8-Positron Emission Tomography. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33495310 DOI: 10.1158/1078-0432.CCR-20-3243  0.113
2011 Torres-Fuenzalida J, Castronuovo C, Hidalgo A, Parada LA, Lorenti A. [Isolation of fetal liver oval cells in physiologic conditions form their natural niche]. Acta Gastroenterologica Latinoamericana. 41: 36-46. PMID 21539067  0.112
2001 Zhu Y, Parada LF. Neurofibromin, a tumor suppressor in the nervous system. Experimental Cell Research. 264: 19-28. PMID 11237520 DOI: 10.1006/excr.2000.5138  0.111
2009 Graham DL, Krishnan V, Larson EB, Graham A, Edwards S, Bachtell RK, Simmons D, Gent LM, Berton O, Bolanos CA, DiLeone RJ, Parada LF, Nestler EJ, Self DW. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biological Psychiatry. 65: 696-701. PMID 18990365 DOI: 10.1016/J.Biopsych.2008.09.032  0.106
2012 Acosta MT, Bearden CE, Castellanos FX, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, et al. The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research. American Journal of Medical Genetics. Part A. 158: 2225-32. PMID 22821737 DOI: 10.1002/Ajmg.A.35535  0.104
2000 Laes J, Parada LA, Johansson B, Levan G, Szpirer C, Szpirer J. Alterations of P19ARF in rodent hepatoma cell lines but not in human primary liver cancer. Cancer Genetics and Cytogenetics. 117: 118-24. PMID 10704681  0.103
2014 Martín-Guerrero I, de Prado E, Lopez-Lopez E, Ardanaz M, Vitoria JC, Parada LA, García-Orad C, García-Orad A. Methylation of the nonhomologous end joining repair pathway genes does not explain the increase of translocations with aging. Age (Dordrecht, Netherlands). 36: 9730. PMID 25399073 DOI: 10.1007/s11357-014-9730-4  0.1
2007 Harada T, Harada C, Parada LF. Molecular regulation of visual system development: more than meets the eye. Genes & Development. 21: 367-78. PMID 17322396 DOI: 10.1101/gad.1504307  0.1
2011 Huson SM, Acosta MT, Belzberg AJ, Bernards A, Chernoff J, Cichowski K, Gareth Evans D, Ferner RE, Giovannini M, Korf BR, Listernick R, North KN, Packer RJ, Parada LF, Peltonen J, et al. Back to the future: proceedings from the 2010 NF Conference. American Journal of Medical Genetics. Part A. 155: 307-21. PMID 21271647 DOI: 10.1002/Ajmg.A.33804  0.1
2000 Nef S, Shipman T, Parada LF. A molecular basis for estrogen-induced cryptorchidism. Developmental Biology. 224: 354-61. PMID 10926772 DOI: 10.1006/dbio.2000.9785  0.092
2019 Llavero F, Arrazola Sastre A, Luque Montoro M, Gálvez P, Lacerda HM, Parada LA, Zugaza JL. McArdle Disease: New Insights into Its Underlying Molecular Mechanisms. International Journal of Molecular Sciences. 20. PMID 31775340 DOI: 10.3390/ijms20235919  0.092
2000 Nef S, Parada LF. Hormones in male sexual development. Genes & Development. 14: 3075-86. PMID 11124800  0.091
2002 Parada LA, McQueen PG, Munson PJ, Misteli T. Conservation of relative chromosome positioning in normal and cancer cells. Current Biology : Cb. 12: 1692-7. PMID 12361574 DOI: 10.1016/S0960-9822(02)01166-1  0.091
1999 Kernie SG, Liebl DJ, Parada LF. Reduction of Brain Derived Neurotrophic Factor Causes Obesity and Hyperactivity: Implications for WAGR Syndrome Pediatric Research. 45: 42A-42A. DOI: 10.1203/00006450-199904020-00253  0.09
2014 Davies C, Dey N, Negrette OS, Parada LA, Basombrio MA, Garg NJ. Hepatotoxicity in mice of a novel anti-parasite drug candidate hydroxymethylnitrofurazone: a comparison with Benznidazole. Plos Neglected Tropical Diseases. 8: e3231. PMID 25329323 DOI: 10.1371/journal.pntd.0003231  0.088
2014 García Bustos MF, Barrio A, Prieto GG, de Raspi EM, Cimino RO, Cardozo RM, Parada LA, Yeo M, Soto J, Uncos DA, Parodi C, Basombrío MA. In vivo antileishmanial efficacy of miltefosine against Leishmania (Leishmania) amazonensis. The Journal of Parasitology. 100: 840-7. PMID 25014108 DOI: 10.1645/13-376.1  0.087
2006 Yue T, Xian K, Hurlock E, Xin M, Kernie SG, Parada LF, Lu QR. A critical role for dorsal progenitors in cortical myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1275-80. PMID 16436615 DOI: 10.1523/Jneurosci.4717-05.2006  0.086
2004 Parada LA, Sotiriou S, Misteli T. Spatial genome organization. Experimental Cell Research. 296: 64-70. PMID 15120995 DOI: 10.1016/J.Yexcr.2004.03.013  0.085
1997 Parada LA, Bardi G, Hallén M, Hägerstrand I, Tranberg KG, Mitelman F, Johansson B. Cytogenetic abnormalities and clonal evolution in an adult hepatoblastoma. The American Journal of Surgical Pathology. 21: 1381-6. PMID 9351578  0.083
2002 Parada L, Misteli T. Chromosome positioning in the interphase nucleus. Trends in Cell Biology. 12: 425-32. PMID 12220863 DOI: 10.1016/S0962-8924(02)02351-6  0.081
2013 Paz N, Zabala A, Royo F, García-Orad Á, Zugaza JL, Parada LA. Combined fluorescent-chromogenic in situ hybridization for identification and laser microdissection of interphase chromosomes. Plos One. 8: e60238. PMID 23565206 DOI: 10.1371/journal.pone.0060238  0.081
2016 Arroyo GF, Gentile A, Parada LA. Gallbladder cancer: South American experience. Chinese Clinical Oncology. 5: 67. PMID 27829280 DOI: 10.21037/cco.2016.10.01  0.079
1999 Parada LA, Marañon A, Hallén M, Tranberg KG, Stenram U, Bardi G, Johansson B. Cytogenetic analyses of secondary liver tumors reveal significant differences in genomic imbalances between primary and metastatic colon carcinomas. Clinical & Experimental Metastasis. 17: 471-9. PMID 10763912  0.077
2013 Burzaco J, Conde M, Parada LA, Zugaza JL, Dehaye JP, Marino A. ATP antagonizes thrombin-induced signal transduction through 12(S)-HETE and cAMP. Plos One. 8: e67117. PMID 23826207 DOI: 10.1371/journal.pone.0067117  0.076
2013 De La Flor FP, Parada LI, De Vicente MA. Regulatory constraints for the competitive operation of LNG terminals: The regulatory debate on coexistence of regulated and unregulated terminals Igt International Liquefied Natural Gas Conference Proceedings. 2: 1420-1445.  0.075
2003 Parada LA, Roix JJ, Misteli T. An uncertainty principle in chromosome positioning. Trends in Cell Biology. 13: 393-6. PMID 12888289 DOI: 10.1016/S0962-8924(03)00149-1  0.073
2012 Robertson KA, Nalepa G, Yang FC, Bowers DC, Ho CY, Hutchins GD, Croop JM, Vik TA, Denne SC, Parada LF, Hingtgen CM, Walsh LE, Yu M, Pradhan KR, Edwards-Brown MK, et al. Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial. The Lancet. Oncology. 13: 1218-24. PMID 23099009 DOI: 10.1016/S1470-2045(12)70414-X  0.07
2008 Parada LF, Zhu Y. Symposium 2: The Genetic, Molecular and Cellular Bases of Neurofibromatosis Type 1 Journal of Neurochemistry. 81: 2-2. DOI: 10.1046/j.1471-4159.81.s1.48_1.x  0.069
2002 Hallén M, Parada LA, Gorunova L, PÃ¥lsson B, Dictor M, Johansson B. Cytogenetic abnormalities in a hemangiopericytoma of the spleen. Cancer Genetics and Cytogenetics. 136: 62-5. PMID 12165454  0.068
2010 Calvo A, Perez-Stable C, Segura V, Catena R, Guruceaga E, Nguewa P, Blanco D, Parada L, Reiner T, Green JE. Molecular characterization of the Ggamma-globin-Tag transgenic mouse model of hormone refractory prostate cancer: comparison to human prostate cancer. The Prostate. 70: 630-45. PMID 20058236 DOI: 10.1002/pros.21097  0.067
2010 Parada LM, Liang X. A novel approach to infer streamflow signals for ungauged basins Advances in Water Resources. 33: 372-386. DOI: 10.1016/J.Advwatres.2010.01.003  0.064
1990 Ramírez R, Nazer J, Hubner ME, Cifuentes L, Ruiz G, Pizarro MT, Parada L. [Incidence of malformations of the central nervous system: 1978-1988]. Revista Mã©Dica De Chile. 118: 530-6. PMID 2293273  0.064
2016 Ameer SS, Xu Y, Engström K, Li H, Tallving P, Nermell B, Boemo A, Parada LA, Peñaloza LG, Concha G, Harari F, Vahter M, Broberg K. Exposure to Inorganic Arsenic Is Associated with Increased Mitochondrial DNA Copy Number and Longer Telomere Length in Peripheral Blood. Frontiers in Cell and Developmental Biology. 4: 87. PMID 27597942 DOI: 10.3389/fcell.2016.00087  0.06
2004 Parada LA, McQueen PG, Misteli T. Tissue-specific spatial organization of genomes. Genome Biology. 5: R44. PMID 15239829 DOI: 10.1186/Gb-2004-5-7-R44  0.06
2018 Simonazzi A, Davies C, Cid AG, Gonzo E, Parada L, Bermúdez JM. Preparation and characterization of Poloxamer 407 solid dispersions as an alternative strategy to improve benznidazole bioperformance. Journal of Pharmaceutical Sciences. PMID 30005984 DOI: 10.1016/j.xphs.2018.06.027  0.051
2020 Davies C, Simonazzi A, Micheloud JF, Ragone PG, Cid AG, Negrette OS, Bermúdez JM, Parada LA. Benznidazole/Poloxamer 407 Solid Dispersion as a New Strategy to Improve the Treatment of Experimental Trypanosoma cruzi Infection. The Journal of Parasitology. 106: 323-333. PMID 32369594 DOI: 10.1645/19-80  0.05
1998 Cohen H, Paolillo E, Bonifacino R, Botta B, Parada L, Cabrera P, Snowden K, Gasser R, Tessier R, Dibarboure L, Wen H, Allan JC, Soto de Alfaro H, Rogan MT, Craig PS. Human cystic echinococcosis in a Uruguayan community: a sonographic, serologic, and epidemiologic study. The American Journal of Tropical Medicine and Hygiene. 59: 620-7. PMID 9790441 DOI: 10.4269/Ajtmh.1998.59.620  0.049
1997 Bardi G, Parada LA, Bomme L, Pandis N, Johansson B, Willén R, Fenger C, Kronborg O, Mitelman F, Heim S. Cytogenetic findings in metastases from colorectal cancer. International Journal of Cancer. Journal International Du Cancer. 72: 604-7. PMID 9259398 DOI: 10.1002/(SICI)1097-0215(19970807)72:4<604::AID-IJC9>3.0.CO;2-U  0.047
1998 Parada LA, Hallén M, Tranberg KG, Hägerstrand I, Bondeson L, Mitelman F, Johansson B. Frequent rearrangements of chromosomes 1, 7, and 8 in primary liver cancer. Genes, Chromosomes & Cancer. 23: 26-35. PMID 9713994 DOI: 10.1002/(SICI)1098-2264(199809)23:1<26::AID-GCC5>3.0.CO;2-8  0.045
2003 Diep CB, Parada LA, Teixeira MR, Eknaes M, Nesland JM, Johansson B, Lothe RA. Genetic profiling of colorectal cancer liver metastases by combined comparative genomic hybridization and G-banding analysis. Genes, Chromosomes & Cancer. 36: 189-97. PMID 12508247 DOI: 10.1002/gcc.10162  0.045
1990 García-Sagredo JM, Parada LA, Monteagudo JL. Effect on SCE in human chromosomes in vitro of low-level pulsed magnetic field. Environmental and Molecular Mutagenesis. 16: 185-8. PMID 2209574  0.044
2022 Qasim S, Hsu SY, Rossi E, Salahshoor Z, Lin CH, Parada LP, Fidalgo M. Detection of progesterone in aqueous samples by molecularly imprinted photonic polymers. Mikrochimica Acta. 189: 174. PMID 35366715 DOI: 10.1007/s00604-022-05290-w  0.044
1999 Gorunova L, Parada LA, Limon J, Jin Y, Hallén M, Hägerstrand I, Iliszko M, Wajda Z, Johansson B. Nonrandom chromosomal aberrations and cytogenetic heterogeneity in gallbladder carcinomas. Genes, Chromosomes & Cancer. 26: 312-21. PMID 10534766 DOI: 10.1002/(SICI)1098-2264(199912)26:4<312::AID-GCC5>3.0.CO;2-3  0.044
1999 Parada LA, Hallén M, Hägerstrand I, Tranberg KG, Johansson B. Clonal chromosomal abnormalities in congenital bile duct dilatation (Caroli's disease). Gut. 45: 780-2. PMID 10517920  0.042
2012 Marco JD, Barroso PA, Mimori T, Locatelli FM, Tomatani A, Mora MC, Cajal SP, Nasser JR, Parada LA, Taniguchi T, Korenaga M, Basombrío MA, Hashiguchi Y. Polymorphism-specific PCR enhances the diagnostic performance of American tegumentary leishmaniasis and allows the rapid identification of Leishmania species from Argentina. Bmc Infectious Diseases. 12: 191. PMID 22894734 DOI: 10.1186/1471-2334-12-191  0.041
1997 Bardi G, Parada LA, Bomme L, Pandis N, Willén R, Johansson B, Jeppsson B, Beroukas K, Heim S, Mitelman F. Cytogenetic comparisons of synchronous carcinomas and polyps in patients with colorectal cancer. British Journal of Cancer. 76: 765-9. PMID 9310243  0.04
2014 Botti LCM, Bo´coli PFJ, Leber ASML, Parada LB, Tribst AAL, Cristianini M. Sanitation of plastic bottles using ozonated water International Food Research Journal. 21: 1375-1379.  0.039
1995 Craig PS, Gasser RB, Parada L, Cabrera P, Parietti S, Borgues C, Acuttis A, Agulla J, Snowden K, Paolillo E. Diagnosis of canine echinococcosis: comparison of coproantigen and serum antibody tests with arecoline purgation in Uruguay. Veterinary Parasitology. 56: 293-301. PMID 7754606 DOI: 10.1016/0304-4017(94)00680-B  0.039
1989 Cifuentes L, Nazer J, Catalán J, Parada L, Ruiz G. [Congenital malformations: a model predictive based on risk factors]. Revista Mã©Dica De Chile. 117: 611-7. PMID 2519408  0.038
2001 Zhu Y, Parada LF. A particular GAP in mind. Nature Genetics. 27: 354-5. PMID 11279509 DOI: 10.1038/86835  0.038
2000 Parada LA, Limon J, Iliszko M, Czauderna P, Gisselsson D, Höglund M, Kullendorff CM, Wiebe T, Mertens F, Johansson B. Cytogenetics of hepatoblastoma: further characterization of 1q rearrangements by fluorescence in situ hybridization: an international collaborative study. Medical and Pediatric Oncology. 34: 165-70. PMID 10696121 DOI: 10.1002/(SICI)1096-911X(200003)34:3<165::AID-MPO1>3.0.CO;2-T  0.036
2012 Parada LF. Neurofibromatosis type 1: Future directions (where do we go from here?) Neurofibromatosis Type 1: Molecular and Cellular Biology. 2147483647: 691-698. DOI: 10.1007/978-3-642-32864-0_44  0.035
2000 Parada LF. Neurofibromatosis type 1. Biochimica Et Biophysica Acta. 1471: M13-9. PMID 10967421  0.034
2016 Parada L, Marstein JP, Danilov A. Tolerability of the COX-1/COX-2 inhibitor lornoxicam in the treatment of acute and rheumatic pain. Pain Management. PMID 27086708 DOI: 10.2217/pmt.16.7  0.034
1992 Ferro MT, Steegman JL, Escribano L, Heiurichs B, Parada L, García-Sagredo JM, Resino M, Cabello P, San Román C. Ph-positive chronic myeloid leukemia with t(8;21)(q22;q22) in blastic crisis. Cancer Genetics and Cytogenetics. 58: 96-9. PMID 1728959  0.034
1993 Gasser RB, Jenkins DJ, Paolillo E, Parada L, Cabrera P, Craig PS. Serum antibodies in canine echinococcosis. International Journal For Parasitology. 23: 579-86. PMID 8225760 DOI: 10.1016/0020-7519(93)90163-S  0.032
2008 Parada LM, Liang X. Impacts of spatial resolutions and data quality on soil moisture data assimilation Journal of Geophysical Research Atmospheres. 113. DOI: 10.1029/2007Jd009037  0.032
2009 Parada L, Fisiatra M. The sportive woman: Gender and physical activity | La mujer deportista: genero y actividad física Informe Medico. 11: 391-392.  0.032
1995 Tessarollo L, Parada LF. In situ hybridization. Methods in Enzymology. 254: 419-30. PMID 8531703 DOI: 10.1016/0076-6879(95)54028-8  0.032
1983 Repetto A, Rossel K, Rivera E, Parada L, Norambuena R, Nuñez M, Parada R, Muñoz J, Podesta L, Peirano R. [Epidemiological description of the medical care of adults in an emergency service]. Revista Mã©Dica De Chile. 111: 1177-82. PMID 6678460  0.031
2013 Acosta MT, Bearden CE, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, Silva AJ. Corrigendum to "The Learning Disabilities Network (LeaDNet): Using Neurofibromatosis Type 1 [NF1] as a Paradigm for Translational Research" American Journal of Medical Genetics, Part A. 161: 236. DOI: 10.1002/Ajmg.A.35667  0.03
2014 Zarco LA, Millán SP, Londoño D, Parada L, Taborda A, Borda MG. [The cost-effectiveness of interferon beta treatment in patients with a clinically isolated syndrome in Colombia]. Biomã©Dica : Revista Del Instituto Nacional De Salud. 34: 110-7. PMID 24967864 DOI: 10.1590/S0120-41572014000100014  0.03
2015 Triana JJ, Castañeda C, Parada L, Otálora-Esteban M, Rosselli D. Cost-effectiveness of dabigatran compared with warfarin in the treatment of patients with non valvular atrial fibrillation in Colombia Revista Colombiana De Cardiologia. DOI: 10.1016/j.rccar.2015.06.010  0.028
2011 Kouznetsov VV, Gómez CM, Parada LK, Bermudez JH, Méndez LY, Acevedo AM. Efficient synthesis and free-radical scavenging capacity of new 2,4-substituted tetrahydroquinolines prepared via BiCl₃-catalyzed three-component Povarov reaction, using N-vinylamides. Molecular Diversity. 15: 1007-16. PMID 21947716 DOI: 10.1007/s11030-011-9330-5  0.027
2015 He D, Wang Z, Parada L. MINED: An efficient mutual information based epistasis detection method to improve quantitative genetic trait prediction Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9096: 108-124. DOI: 10.1007/978-3-319-19048-8_10  0.023
2015 Parada L, Herrera C, Sepúlveda M, Parada V. Evolution of new algorithms for the binary knapsack problem Natural Computing. DOI: 10.1007/S11047-015-9483-8  0.02
1995 Parada L, Cabrera P, Burges C, Acuña A, Barcelona C, Laurenson MK, Gulland FM, Agulla J, Parietti S, Paolillo E. Echinococcus granulosus infections of dogs in the Durazno region of Uruguay. The Veterinary Record. 136: 389-91. PMID 7604519  0.02
1989 Nazer J, Castillo S, Cifuentes L, Ruiz G, Pizarro MT, Parada L. [Incidence of congenital malformations in Chile from 1969 to 1986. Results of a Latin-American collaborative study]. Revista Mã©Dica De Chile. 117: 219-27. PMID 2487963  0.018
2000 Bassol S, Cravioto MC, Durand M, Bailon R, Carranza S, Fugarolas J, Gaona R, Parada LM, Celis C, Santoyo S, Garza-Flores J, Vazquez L, Lopez C, Gurucharri C, Novelli J, et al. Mesigyna once-a-month combined injectable contraceptive: experience in Latin America. Contraception. 61: 309-16. PMID 10906501 DOI: 10.1016/S0010-7824(00)00109-8  0.018
2009 Zhou J, Parada LF. A motor driving PTEN. Nature Cell Biology. 11: 1177-9. PMID 19794503 DOI: 10.1038/ncb1009-1177  0.016
2013 Parada L, Sepulveda M, Herrera C, Parada V. Automatic generation of algorithms for the binary knapsack problem 2013 Ieee Congress On Evolutionary Computation, Cec 2013. 3148-3152. DOI: 10.1109/CEC.2013.6557954  0.014
2014 Zarco LA, Millán SP, Londoño D, Parada L, Taborda A, Borda MG. The cost-effectiveness of interferon beta treatment in patients with a clinically isolated syndrome in Colombia | Costo-efectividad del tratamiento con interferón beta en pacientes con síndrome clínico aislado de alto riesgo en Colombia Biomedica. 34: 110-117. DOI: 10.7705/biomedica.v34i1.1541  0.014
1989 Nazer J, Cifuentes L, Catalán J, Pizarro MT, Ruiz G, Parada L. [Incidence of congenital malformations among stillborns]. Revista Chilena De Pediatrã­A. 60: 208-11. PMID 2485510  0.013
1994 Gasser RB, Parada L, Acuna A, Burges C, Laurenson MK, Gulland FM, Reichel MP, Paolillo E. Immunological assessment of exposure to Echinococcus granulosus in a rural dog population in Uruguay. Acta Tropica. 58: 179-85. PMID 7709857  0.012
1997 Parada LA, Bardi G, Hallén M, Hägerstrand I, Tranberg KG, Mitelman F, Johansson B. Monosomy 22 in a case of biliary adenofibroma. Cancer Genetics and Cytogenetics. 93: 183-4. PMID 9078308  0.012
2011 Parada LV. Public health: Life lessons. Nature. 480: S11-3. PMID 22158294 DOI: 10.1038/480S11a  0.01
1993 Cifuentes L, Nazer J, Armanet L, Ruiz G, Parada L, Pizarro MT. [MN blood group and congenital malformations]. Revista Mã©Dica De Chile. 121: 385-9. PMID 8272607  0.01
1967 Torres Zamora M, Parada LM, Zajarías S. [Natural history of essential arterial hypertension]. Archivos Del Instituto De Cardiologã­a De Mã©Xico. 37: 345-51. PMID 6057346  0.01
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