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James J. Chambers, Ph.D. - Publications

2004-2007 MCB University of California, Berkeley, Berkeley, CA 
 2008- Chemistry University of Massachusetts, Amherst, Amherst, MA 
Chemical Biology, Neuroscience

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 McCarron ST, Chambers JJ. Modular chemical probes for visualizing and tracking endogenous ion channels. Neuropharmacology. PMID 25866020 DOI: 10.1016/j.neuropharm.2015.03.033  0.686
2015 Combs-Bachmann RE, Johnson JN, Vytla D, Hussey AM, Kilfoil ML, Chambers JJ. Ligand-directed delivery of fluorophores to track native calcium-permeable AMPA receptors in neuronal cultures. Journal of Neurochemistry. 133: 320-9. PMID 25640258 DOI: 10.1111/jnc.13051  0.673
2015 Hussey AM, Chambers JJ. Methods to locate and track ion channels and receptors expressed in live neurons. Acs Chemical Neuroscience. 6: 189-98. PMID 25307447 DOI: 10.1021/cn5002057  0.593
2014 Lin WC, Davenport CM, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH. Engineering a light-regulated GABAA receptor for optical control of neural inhibition. Acs Chemical Biology. 9: 1414-9. PMID 24819442 DOI: 10.1021/Cb500167U  0.769
2013 McCarron ST, Feliciano M, Johnson JN, Chambers JJ. Photoinitiated release of an aziridinium ion precursor for the temporally controlled alkylation of nucleophiles. Bioorganic & Medicinal Chemistry Letters. 23: 2395-8. PMID 23489632 DOI: 10.1016/j.bmcl.2013.02.044  0.628
2013 Hussey AM, Combs-Bachmann RE, Vytla D, Hafez I, Chambers JJ. Development of an Activity Dependent, Photochemically-Released Tool for the Study of Calcium Permeable AMPA Receptors Biophysical Journal. 104: 499a. DOI: 10.1016/J.Bpj.2012.11.2752  0.66
2012 Vytla D, Combs-Bachmann RE, Hussey AM, McCarron ST, McCarthy DS, Chambers JJ. Prodrug approaches to reduce hyperexcitation in the CNS. Advanced Drug Delivery Reviews. 64: 666-85. PMID 22138074 DOI: 10.1016/j.addr.2011.11.007  0.7
2012 Davenport CM, Lin W, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH. Optical Control of Neuronal Inhibition with Genetically Engineered Light Inhibited GABAA Receptors (Li-GABARs) Biophysical Journal. 102: 111a. DOI: 10.1016/J.Bpj.2011.11.626  0.76
2011 Vytla D, Combs-Bachmann RE, Hussey AM, Hafez I, Chambers JJ. Silent, fluorescent labeling of native neuronal receptors. Organic & Biomolecular Chemistry. 9: 7151-61. PMID 21897969 DOI: 10.1039/C1Ob05963G  0.66
2011 Jackman SL, Babai N, Chambers JJ, Thoreson WB, Kramer RH. A positive feedback synapse from retinal horizontal cells to cone photoreceptors. Plos Biology. 9: e1001057. PMID 21559323 DOI: 10.1371/Journal.Pbio.1001057  0.752
2011 Lin W, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH. Optogenetic GABAA Receptors: Controlling Neural Inhibition with Light Biophysical Journal. 100: 24a-25a. DOI: 10.1016/J.Bpj.2010.12.340  0.799
2011 Chambers JJ, Kramer RH. Introduction to part III: Small molecule photoswitches Neuromethods. 55: 167-169. DOI: 10.1007/978-1-61779-031-7_9  0.412
2011 Chambers JJ, Kramer RH. Introduction to part II: Natural photosensitive proteins Neuromethods. 55: 95-97. DOI: 10.1007/978-1-61779-031-7_5  0.403
2011 Chambers JJ, Kramer RH. Introduction to part I: Caged neurotransmitters Neuromethods. 55: 3-5. DOI: 10.1007/978-1-61779-031-7_1  0.47
2011 Chambers JJ, Kramer RH. Neuromethods: Preface Neuromethods. 55: vii-ix.  0.388
2010 Feliciano M, Vytla D, Medeiros KA, Chambers JJ. The GABA(A) receptor as a target for photochromic molecules. Bioorganic & Medicinal Chemistry. 18: 7731-8. PMID 20646926 DOI: 10.1016/j.bmc.2010.05.056  0.624
2008 Chambers JJ, Kramer RH. Light-activated ion channels for remote control of neural activity. Methods in Cell Biology. 90: 217-32. PMID 19195553 DOI: 10.1016/S0091-679X(08)00811-X  0.533
2006 Chambers JJ, Banghart MR, Trauner D, Kramer RH. Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch. Journal of Neurophysiology. 96: 2792-6. PMID 16870840 DOI: 10.1152/Jn.00318.2006  0.742
2006 McLean TH, Chambers JJ, Parrish JC, Braden MR, Marona-Lewicka D, Kurrasch-Orbaugh D, Nichols DE. C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor. Journal of Medicinal Chemistry. 49: 4269-74. PMID 16821786 DOI: 10.1021/Jm060272Y  0.733
2005 Kramer RH, Chambers JJ, Trauner D. Photochemical tools for remote control of ion channels in excitable cells. Nature Chemical Biology. 1: 360-5. PMID 16370371 DOI: 10.1038/Nchembio750  0.649
2004 Chambers JJ, Gouda H, Young DM, Kuntz ID, England PM. Photochemically knocking out glutamate receptors in vivo. Journal of the American Chemical Society. 126: 13886-7. PMID 15506725 DOI: 10.1021/ja048331p  0.459
2003 Chambers JJ, Parrish JC, Jensen NH, Kurrasch-Orbaugh DM, Marona-Lewicka D, Nichols DE. Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands. Journal of Medicinal Chemistry. 46: 3526-35. PMID 12877591 DOI: 10.1021/Jm030064V  0.761
2002 Chambers JJ, Nichols DE. A homology-based model of the human 5-HT2A receptor derived from an in silico activated G-protein coupled receptor. Journal of Computer-Aided Molecular Design. 16: 511-20. PMID 12510883 DOI: 10.1023/A:1021275430021  0.603
2002 Chambers JJ, Kurrasch-Orbaugh DM, Nichols DE. Translocation of the 5-alkoxy substituent of 2,5-dialkoxyarylalkylamines to the 6-position: effects on 5-HT(2A/2C) receptor affinity. Bioorganic & Medicinal Chemistry Letters. 12: 1997-9. PMID 12113827 DOI: 10.1016/S0960-894X(02)00306-2  0.782
2001 Chambers JJ, Kurrasch-Orbaugh DM, Parker MA, Nichols DE. Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT(2A/2C) receptor agonists. Journal of Medicinal Chemistry. 44: 1003-10. PMID 11300881 DOI: 10.1021/Jm000491Y  0.792
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