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Nica M. Borradaile, Ph.D. - Publications

Affiliations: 
2003 The University of Western Ontario (Canada) 
Area:
Biochemistry, Nutrition
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wilson RB, Kozlov AM, Tehrani HH, Twumasi Ankrah JS, Chen YJ, Borrelli MJ, Sawyez CG, Maini S, Shepherd TG, Cumming RC, Betts DH, Borradaile NM. Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells. The Journal of Biological Chemistry. 105684. PMID 38272231 DOI: 10.1016/j.jbc.2024.105684  0.301
2020 Wilson RB, Chen YJ, Sutherland BG, Sawyez CG, Zhang R, Woolnough T, Hetherington AM, Peters KM, Patel K, Kennelly JP, Leonard KA, Schuurman M, Jacobs RL, Wang R, Borradaile NM. The marine compound and elongation factor 1A1 inhibitor, didemnin B, provides benefit in western diet-induced non-alcoholic fatty liver disease. Pharmacological Research. 105208. PMID 32977024 DOI: 10.1016/j.phrs.2020.105208  0.312
2019 Peters KM, Borradaile NM. Microarray data and pathway analyses for human microvascular endothelial cells supplemented with low dose vitamin D or niacin during lipotoxicity. Data in Brief. 26: 104490. PMID 31667254 DOI: 10.1016/J.Dib.2019.104490  0.312
2018 Peters KM, Wilson RB, Borradaile NM. Non-parenchymal hepatic cell lipotoxicity and the coordinated progression of non-alcoholic fatty liver disease and atherosclerosis. Current Opinion in Lipidology. PMID 30015675 DOI: 10.1097/Mol.0000000000000535  0.321
2017 Ratneswaran A, Sun MM, Dupuis H, Sawyez C, Borradaile N, Beier F. Nuclear receptors regulate lipid metabolism and oxidative stress markers in chondrocytes. Journal of Molecular Medicine (Berlin, Germany). PMID 28070626 DOI: 10.1007/S00109-016-1501-5  0.374
2017 Hetherington AM, Sawyez CG, Borradaile NM. Microarray data and pathway analyses for primary human activated hepatic stellate cells compared to HepG2 human hepatoma cells. Data in Brief. 10: 385-389. PMID 28050580 DOI: 10.1016/J.Dib.2016.12.011  0.347
2016 Hetherington AM, Sawyez CG, Zilberman E, Stoianov AM, Robson DL, Borradaile NM. Differential Lipotoxic Effects of Palmitate and Oleate in Activated Human Hepatic Stellate Cells and Epithelial Hepatoma Cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 1648-1662. PMID 27626926 DOI: 10.1159/000447866  0.376
2016 Hetherington AM, Sawyez CG, Sutherland BG, Robson DL, Arya R, Kelly K, Jacobs RL, Borradaile NM. Treatment with didemnin B, an elongation factor 1A inhibitor, improves hepatic lipotoxicity in obese mice. Physiological Reports. 4. PMID 27613825 DOI: 10.14814/Phy2.12963  0.385
2016 Pang DK, Nong Z, Sutherland BG, Sawyez CG, Robson DL, Toma J, Pickering JG, Borradaile NM. Niacin promotes revascularization and recovery of limb function in diet-induced obese mice with peripheral ischemia. Pharmacology Research & Perspectives. 4: e00233. PMID 27433343 DOI: 10.1002/Prp2.233  0.34
2016 Hughes-Large JM, Borradaile NM. Gene expression microarray data from human microvascular endothelial cells supplemented with a low concentration of niacin. Data in Brief. 6: 899-902. PMID 26937468 DOI: 10.1016/J.Dib.2016.01.039  0.33
2015 Stoianov AM, Robson DL, Hetherington AM, Sawyez CG, Borradaile NM. Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Function in Protein Synthesis. Plos One. 10: e0131269. PMID 26102086 DOI: 10.1371/Journal.Pone.0131269  0.37
2015 Ratneswaran A, LeBlanc EA, Walser E, Welch I, Mort JS, Borradaile N, Beier F. Peroxisome proliferator-activated receptor δ promotes the progression of posttraumatic osteoarthritis in a mouse model Arthritis and Rheumatology. 67: 454-464. PMID 25331977 DOI: 10.1002/Art.38915  0.302
2014 Hughes-Large JM, Pang DK, Robson DL, Chan P, Toma J, Borradaile NM. Niacin receptor activation improves human microvascular endothelial cell angiogenic function during lipotoxicity. Atherosclerosis. 237: 696-704. PMID 25463108 DOI: 10.1016/J.Atherosclerosis.2014.10.090  0.361
2010 Borradaile NM, Pickering JG. Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase. American Journal of Physiology. Cell Physiology. 298: C66-74. PMID 19846757 DOI: 10.1152/Ajpcell.00357.2009  0.356
2009 Borradaile NM, Pickering JG. Nicotinamide phosphoribosyltransferase imparts human endothelial cells with extended replicative lifespan and enhanced angiogenic capacity in a high glucose environment. Aging Cell. 8: 100-12. PMID 19302375 DOI: 10.1111/J.1474-9726.2009.00453.X  0.318
2009 Borradaile NM, Pickering JG. NAD(+), sirtuins, and cardiovascular disease. Current Pharmaceutical Design. 15: 110-7. PMID 19149606 DOI: 10.2174/138161209787185742  0.343
2006 Borradaile NM, Han X, Harp JD, Gale SE, Ory DS, Schaffer JE. Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death. Journal of Lipid Research. 47: 2726-37. PMID 16960261 DOI: 10.1194/Jlr.M600299-Jlr200  0.396
2006 Borradaile NM, Buhman KK, Listenberger LL, Magee CJ, Morimoto ET, Ory DS, Schaffer JE. A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death. Molecular Biology of the Cell. 17: 770-8. PMID 16319173 DOI: 10.1091/Mbc.E05-08-0742  0.365
2005 Borradaile NM, Schaffer JE. Lipotoxicity in the heart. Current Hypertension Reports. 7: 412-7. PMID 16386196 DOI: 10.1007/S11906-005-0035-Y  0.302
2005 Allister EM, Borradaile NM, Edwards JY, Huff MW. Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes. Diabetes. 54: 1676-83. PMID 15919788 DOI: 10.2337/Diabetes.54.6.1676  0.596
2003 Borradaile NM, de Dreu LE, Huff MW. Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation. Diabetes. 52: 2554-61. PMID 14514640 DOI: 10.2337/Diabetes.52.10.2554  0.607
2003 Borradaile NM, de Dreu LE, Barrett PH, Behrsin CD, Huff MW. Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation. Biochemistry. 42: 1283-91. PMID 12564931 DOI: 10.1021/Bi026731O  0.646
2002 Borradaile NM, de Dreu LE, Barrett PH, Huff MW. Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters. Journal of Lipid Research. 43: 1544-54. PMID 12235187 DOI: 10.1194/Jlr.M200115-Jlr200  0.626
2002 Borradaile NM, de Dreu LE, Wilcox LJ, Edwards JY, Huff MW. Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms. The Biochemical Journal. 366: 531-9. PMID 12030847 DOI: 10.1042/Bj20020046  0.65
2001 Wilcox LJ, Borradaile NM, de Dreu LE, Huff MW. Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. Journal of Lipid Research. 42: 725-34. PMID 11352979  0.635
2000 Kurowska E, Borradaile N, Spence J, Carroll K. Hypocholesterolemic effects of dietary citrus juices in rabbits Nutrition Research. 20: 121-129. DOI: 10.1016/S0271-5317(99)00144-X  0.599
1999 Borradaile NM, Carroll KK, Kurowska EM. Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin. Lipids. 34: 591-8. PMID 10405973 DOI: 10.1007/S11745-999-0403-7  0.628
1999 Wilcox LJ, Borradaile NM, Huff MW. Antiatherogenic Properties of Naringenin, a Citrus Flavonoid Cardiovascular Drug Reviews. 17: 160-178. DOI: 10.1111/J.1527-3466.1999.Tb00011.X  0.472
1997 Kurowska E, Borradaile N, Meade M, Spence J, Carroll K. 4.P.162 Cholesterol-lowering effects of dietary citrus juices and their flavonoids. Studies in rats, mice and rabbits Atherosclerosis. 134: 330. DOI: 10.1016/S0021-9150(97)89688-8  0.561
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