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William Jonathan Lederer - Publications

Affiliations: 
University of Maryland, College Park, College Park, MD 
Area:
heart, calcium
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Year Citation  Score
2023 Stern H, Lederer WJ. Changes in the Salivary Secretion, Affected by Systemic Disease. International Dental Journal (Philadelphia, Pa.). 26: 106-120. PMID 37913254  0.327
2022 Ullah A, Hoang-Trong MT, Lederer WJ, Winslow RL, Jafri MS. Critical Requirements for the Initiation of a Cardiac Arrhythmia in Rat Ventricle: How Many Myocytes? Cells. 11. PMID 35741007 DOI: 10.3390/cells11121878  0.612
2021 Hoang-Trong TM, Ullah A, Lederer WJ, Jafri MS. A Stochastic Spatiotemporal Model of Rat Ventricular Myocyte Calcium Dynamics Demonstrated Necessary Features for Calcium Wave Propagation. Membranes. 11. PMID 34940490 DOI: 10.3390/membranes11120989  0.574
2021 Hoang-Trong MT, Ullah A, Lederer WJ, Jafri MS. Cardiac Alternans Occurs through the Synergy of Voltage- and Calcium-Dependent Mechanisms. Membranes. 11. PMID 34677560 DOI: 10.3390/membranes11100794  0.587
2021 Limbu S, Prosser BL, Lederer WJ, Ward CW, Jafri MS. X-ROS Signaling Depends on Length-Dependent Calcium Buffering by Troponin. Cells. 10. PMID 34068012 DOI: 10.3390/cells10051189  0.48
2020 Zhao G, Joca HC, Nelson MT, Lederer WJ. ATP- and voltage-dependent electro-metabolic signaling regulates blood flow in heart. Proceedings of the National Academy of Sciences of the United States of America. PMID 32170008 DOI: 10.1073/Pnas.1922095117  0.486
2020 Zhao G, Joca HC, Nelson MT, Lederer WJ. ATP- and voltage-dependent electro-metabolic signaling regulates blood flow in heart. Proceedings of the National Academy of Sciences of the United States of America. PMID 32170008 DOI: 10.1073/Pnas.1922095117  0.486
2020 Wescott AP, Kao JPY, Lederer WJ, Boyman L. Mitochondrial Calcium Signaling Tunes Voltage‐Energized ATP Production The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.02798  0.427
2020 Zhao G, Joca HC, Lederer WJ. Blood Flow Control of the Microcirculation by K ATP Channels in Ventricular Myocytes The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.00272  0.407
2020 Coleman AK, Cavalcante Joca H, Shi G, Lederer WJ, Ward CW. Microtubule Acetylation Regulates Striated Muscle Mechanotransduction Biophysical Journal. 118: 424a. DOI: 10.1016/j.bpj.2019.11.2388  0.37
2020 Joca HC, Garber L, Coleman A, Boyman L, Karbowski M, Ward CW, Lederer WJ, Greiser M. Atrial Myocytes Maintain Low [Na+]I through Specialized Na+/K+ ATPase Microdomain Biophysical Journal. 118: 267a. DOI: 10.1016/j.bpj.2019.11.1544  0.403
2020 Boyman L, Lefkimmiatis K, Pozzan T, Lederer WJ, Greiser M. Soluble Adenylyl Cyclase at the Nanoscale: Imaging and Function in Heart Biophysical Journal. 118: 246a. DOI: 10.1016/j.bpj.2019.11.1440  0.395
2020 Wescott AP, Kao JP, Lederer WJ, Boyman L. Voltage-Energized Calcium-Sensitive ATP Production by Mitochondria Biophysical Journal. 118: 184a. DOI: 10.1016/j.bpj.2019.11.1123  0.444
2020 Yasin S, Kaplan AD, Joca HC, Lederer WJ, Greiser M. ‘Calcium Clock’ at the Nanoscale in the RAT SA Node: 3D Ryanodine Receptor Cluster Organization and Intracellular Ca2+ Signaling Biophysical Journal. 118: 173a. DOI: 10.1016/j.bpj.2019.11.1056  0.469
2019 Wescott AP, Kao JPY, Lederer WJ, Boyman L. Voltage-energized Calcium-sensitive ATP Production by Mitochondria. Nature Metabolism. 1: 975-984. PMID 31950102 DOI: 10.1016/J.Bpj.2019.11.1123  0.601
2019 Wescott AP, Kao JPY, Lederer WJ, Boyman L. Voltage-energized Calcium-sensitive ATP Production by Mitochondria. Nature Metabolism. 1: 975-984. PMID 31950102 DOI: 10.1016/J.Bpj.2019.11.1123  0.601
2019 Boyman L, Karbowski M, Lederer WJ. Regulation of Mitochondrial ATP Production: Ca Signaling and Quality Control. Trends in Molecular Medicine. 26: 21-39. PMID 31767352 DOI: 10.1016/j.molmed.2019.10.007  0.633
2019 Boyman L, Coleman AK, Zhao G, Wescott AP, Joca HC, Greiser BM, Karbowski M, Ward CW, Lederer WJ. Dynamics of the mitochondrial permeability transition pore: Transient and permanent opening events. Archives of Biochemistry and Biophysics. PMID 30930285 DOI: 10.1016/j.abb.2019.03.016  0.437
2019 Wescott AP, Kao JPY, Lederer WJ, Boyman L. Author Correction: Voltage-energized calcium-sensitive ATP production by mitochondria Nature Metabolism. 1: 1168-1168. DOI: 10.1038/s42255-019-0143-7  0.439
2019 Mannella CA, Liu Z, Hsieh C, Afzal N, Adams RA, Jafri MS, Lederer WJ. How the Nanoarchitecture of Cardiac Muscle Mitochondria Affects Function: Lessons from Computer Simulations Biophysical Journal. 116: 155a. DOI: 10.1016/J.Bpj.2018.11.860  0.418
2019 Zhao G, Joca HC, Lederer WJ. Blood Flow Control by ATP-Sensitive Potassium Channel in Heart Biophysical Journal. 116: 31a-32a. DOI: 10.1016/j.bpj.2018.11.211  0.424
2019 Greiser M, Joca HC, Lederer WJ. Pacemaker Organization at the Nanoscale: Imaging of Ryanodine Receptors as Clusters in Single Sinoatrial Nodal Cells Biophysical Journal. 116: 380a. DOI: 10.1016/j.bpj.2018.11.2065  0.354
2019 Afzal N, Mannella CA, Lederer WJ, Jafri MS. Cardiac Calcium Signaling and Mitochondrial Metabolic Function Biophysical Journal. 116: 270a. DOI: 10.1016/J.Bpj.2018.11.1463  0.455
2019 Adams R, Liu Z, Mannella CA, Lederer WJ, Jafri MS. An Automated Method for Segmenting Highly Convoluted Mitochondrial Inner Membranes from Electron Microscopic Tomograms Biophysical Journal. 116: 267a. DOI: 10.1016/J.Bpj.2018.11.1447  0.357
2019 Afzal N, Mannella C, Lederer WJ, Jafri MS. Mitochondrial Metabolic Function is Affected by Inner Membrane Morphology Biophysical Journal. 116: 266a-267a. DOI: 10.1016/J.Bpj.2018.11.1446  0.368
2019 Coleman AK, Joca HC, Williams GS, Lederer WJ, Ward CW. Microtubule Acetylation Regulates Contractile Kinetics of Striated Muscle Biophysical Journal. 116: 266a. DOI: 10.1016/j.bpj.2018.11.1444  0.379
2019 Garber L, Joca HC, Williams GS, Ward CW, Lederer W, Greiser M. Dynamic Regulation of Sodium Homeostasis in Atrial Myocytes Biophysical Journal. 116: 245a. DOI: 10.1016/j.bpj.2018.11.1342  0.403
2019 Wescott AP, Kao JP, Lederer WJ, Boyman L. Mitochondrial Calcium Signaling in Heart Biophysical Journal. 116: 238a. DOI: 10.1016/J.Bpj.2018.11.1307  0.46
2018 Joca HC, Williams GS, Lederer WJ, Ward CW. Dynamics of Stretch-Dependent Calcium Signaling in Heart Biophysical Journal. 114: 110a. DOI: 10.1016/j.bpj.2017.11.636  0.463
2018 Vanegas C, Joca H, Vandermeulen J, Khairallah R, Lederer WJ, Stains J, Ward CW. Skeletal Muscle Contraction Alters Microtubule Properties that Impact Function Biophysical Journal. 114: 505a-506a. DOI: 10.1016/J.Bpj.2017.11.2763  0.379
2018 Wescott AP, Kao JP, Lederer WJ, Boyman L. Regulation of ATP Production by Mitochondrial Calcium Signals in Heart Biophysical Journal. 114: 466a. DOI: 10.1016/J.Bpj.2017.11.2570  0.461
2017 Sobie EA, Williams GSB, Lederer WJ. Ambiguous interactions between diastolic and SR Ca(2+) in the regulation of cardiac Ca(2+) release. The Journal of General Physiology. PMID 28798276 DOI: 10.1085/Jgp.201711814  0.59
2017 Garber L, Lederer WJ, Greiser M. Characterization of Intracellular Sodium Homeostasis in Murine Atrial Myocytes Biophysical Journal. 112: 96a. DOI: 10.1016/j.bpj.2016.11.557  0.477
2017 Limbu S, Prosser BL, Lederer WJ, Jafri MS. The Interplay between Length-Dependent Calcium Affinity of Troponin and X-ROS Signaling on Myoplasmic Calcium Levels in Heart Biophysical Journal. 112: 95a. DOI: 10.1016/J.Bpj.2016.11.554  0.46
2017 Williams GS, Wescott AP, Lehnart SE, Lederer W. How Does Calcium Overload Generate Calcium Waves in Heart? Biophysical Journal. 112: 541a. DOI: 10.1016/j.bpj.2016.11.2923  0.441
2017 Wescott AP, Boyman L, Lederer WJ, Williams GS. Calcium Regulation of Cardiac Bioenergetics Biophysical Journal. 112: 536a. DOI: 10.1016/j.bpj.2016.11.2901  0.47
2017 Afzal N, Lederer WJ, Jafri MS. Mitochondrial Permeability Transition Pore and Number of Openings Biophysical Journal. 112: 440a. DOI: 10.1016/J.Bpj.2016.11.2350  0.496
2017 Zhao G, Joca H, Lederer WJ. Dynamic Blood Flow Control in Heart Biophysical Journal. 112: 36a. DOI: 10.1016/j.bpj.2016.11.229  0.367
2016 Lin Q, Zhao G, Fang X, Peng X, Tang H, Wang H, Jing R, Liu J, Lederer WJ, Chen J, Ouyang K. IP3 receptors regulate vascular smooth muscle contractility and hypertension. Jci Insight. 1: e89402. PMID 27777977 DOI: 10.1172/jci.insight.89402  0.483
2016 Brandenburg S, Kohl T, Williams GS, Gusev K, Wagner E, Rog-Zielinska EA, Hebisch E, Dura M, Didié M, Gotthardt M, Nikolaev VO, Hasenfuss G, Kohl P, Ward CW, Lederer WJ, et al. Axial tubule junctions control rapid calcium signaling in atria. The Journal of Clinical Investigation. PMID 27643434 DOI: 10.1172/Jci88241  0.58
2016 Brandenburg S, Kohl T, Williams GS, Gusev K, Wagner E, Rog-Zielinska EA, Hebisch E, Dura M, Didié M, Gotthardt M, Nikolaev VO, Hasenfuss G, Kohl P, Ward CW, Lederer WJ, et al. Axial tubule junctions control rapid calcium signaling in atria. The Journal of Clinical Investigation. PMID 27643434 DOI: 10.1172/Jci88241  0.58
2016 Wescott AP, Jafri MS, Lederer WJ, Williams GS. Ryanodine receptor sensitivity governs the stability and synchrony of local calcium release during cardiac excitation-contraction coupling. Journal of Molecular and Cellular Cardiology. PMID 26827896 DOI: 10.1016/J.Bpj.2015.11.581  0.62
2016 Brandenburg S, Kohl T, Williams GS, Gusev K, Wagner E, Hebisch E, Ward CW, Lederer W, Lehnart S. 168-03: Axial membrane tubules in atrial myocytes initiate rapid intracellular calcium signals through a new “super-hub” mechanism Ep Europace. 18: i114-i114. DOI: 10.1093/europace/18.suppl_1.i114  0.46
2016 Boyman L, Kao JP, Leach JB, Lederer WJ, Williams GS. Fluorescence Measurement of Pericellular Oxygen Biophysical Journal. 110: 472a. DOI: 10.1016/J.Bpj.2015.11.2525  0.406
2016 Greiser M, Khairallah RJ, Ward C, Lederer WJ. X-ROS Signaling in Atrial Myocytes Produces Arrhythmogenic Ca2+ Waves Biophysical Journal. 110: 434a. DOI: 10.1016/J.Bpj.2015.11.2342  0.584
2016 Zhao G, Zhang H, Li T, Brochet DX, Rosenberg P, Lederer WJ. The Function of Stromal Interaction Molecule 1 (STIM1) in Heart Biophysical Journal. 110: 360a. DOI: 10.1016/J.Bpj.2015.11.1942  0.613
2016 Brandenburg S, Kohl T, Williams GS, Gusev K, Wagner E, Hebisch E, Ward CW, Lederer W, Lehnart SE. Axial Membrane Tubules in Atrial Cardiomyocytes Confine Ultrarapid Intracellular Calcium Signals through a New Super-Hub Mechanism Biophysical Journal. 110: 267a. DOI: 10.1016/j.bpj.2015.11.1454  0.459
2016 Kerr JP, Shi G, Lederer WJ, Virgilio KM, Blemker SS, Martin SS, Raiteri R, Ward CW. Microtubule-Dependent Alterations to Mechanical Properties and Mechanotransduction in Skeletal Muscle Biophysical Journal. 110: 182a-183a. DOI: 10.1016/J.Bpj.2015.11.1017  0.471
2015 Limbu S, Hoang-Trong TM, Prosser BL, Lederer WJ, Jafri MS. Modeling Local X-ROS and Calcium Signaling in the Heart. Biophysical Journal. 109: 2037-50. PMID 26588563 DOI: 10.1016/J.Bpj.2015.09.031  0.585
2015 Xu S, Cherok E, Das S, Li S, Roelofs BA, Ge SX, Polster BM, Boyman L, Lederer WJ, Wang C, Karbowski M. Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein. Molecular Biology of the Cell. PMID 26564796 DOI: 10.1091/Mbc.E15-09-0678  0.381
2015 Walker MA, Kohl T, Lehnart SE, Greenstein JL, Lederer WJ, Winslow RL. On the Adjacency Matrix of RyR2 Cluster Structures. Plos Computational Biology. 11: e1004521. PMID 26545234 DOI: 10.1371/Journal.Pcbi.1004521  0.56
2015 Zhang H, Sun AY, Kim JJ, Graham V, Finch EA, Nepliouev I, Zhao G, Li T, Lederer WJ, Stiber JA, Pitt GS, Bursac N, Rosenberg PB. STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node. Proceedings of the National Academy of Sciences of the United States of America. PMID 26424448 DOI: 10.1073/Pnas.1503847112  0.616
2015 Boyman L, Williams GS, Lederer WJ. The growing importance of mitochondrial calcium in health and disease. Proceedings of the National Academy of Sciences of the United States of America. 112: 11150-1. PMID 26311848 DOI: 10.1073/pnas.1514284112  0.399
2015 Zhao G, Li T, Brochet DX, Rosenberg PB, Lederer WJ. STIM1 enhances SR Ca2+ content through binding phospholamban in rat ventricular myocytes. Proceedings of the National Academy of Sciences of the United States of America. 112: E4792-801. PMID 26261328 DOI: 10.1073/Pnas.1423295112  0.6
2015 Zhang M, Prosser BL, Bamboye MA, Gondim AN, Santos CX, Martin D, Ghigo A, Perino A, Brewer AC, Ward CW, Hirsch E, Lederer WJ, Shah AM. Contractile Function During Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation. Journal of the American College of Cardiology. 66: 261-72. PMID 26184620 DOI: 10.1016/J.Jacc.2015.05.020  0.415
2015 Previs MJ, Prosser BL, Mun JY, Previs SB, Gulick J, Lee K, Robbins J, Craig R, Lederer WJ, Warshaw DM. Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling. Science Advances. 1. PMID 25839057 DOI: 10.1126/Sciadv.1400205  0.461
2015 Clancy CE, Chen-Izu Y, Bers DM, Belardinelli L, Boyden PA, Csernoch L, Despa S, Fermini B, Hool LC, Izu L, Kass RS, Lederer WJ, Louch WE, Maack C, Matiazzi A, et al. Deranged sodium to sudden death. The Journal of Physiology. 593: 1331-45. PMID 25772289 DOI: 10.1113/Jphysiol.2014.281204  0.648
2015 Li S, Xu S, Roelofs BA, Boyman L, Lederer WJ, Sesaki H, Karbowski M. Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission. The Journal of Cell Biology. 208: 109-23. PMID 25547155 DOI: 10.1083/Jcb.201404050  0.381
2015 Williams GS, Boyman L, Lederer WJ. Mitochondrial calcium and the regulation of metabolism in the heart. Journal of Molecular and Cellular Cardiology. 78: 35-45. PMID 25450609 DOI: 10.1016/j.yjmcc.2014.10.019  0.592
2015 Zhao G, Li T, Brochet DXP, Rosenberg PB, Lederer WJ. STIM1 enhances SR Ca2+ content through binding phospholamban in rat ventricular myocytes Proceedings of the National Academy of Sciences of the United States of America. 112: E4792-E4801. DOI: 10.1073/pnas.1423295112  0.538
2015 Zhang M, Prosser BL, Bamboye MA, Gondim ANS, Santos CX, Martin D, Ghigo A, Perino A, Brewer AC, Ward CW, Hirsch E, Lederer WJ, Shah AM. Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation Journal of the American College of Cardiology. 66: 261-272. DOI: 10.1016/j.jacc.2015.05.020  0.448
2015 Greiser M, Ward C, Lederer WJ. Stretch-Induced Changes in Atrial Ca Signaling Biophysical Journal. 108: 178a-179a. DOI: 10.1016/j.bpj.2014.11.986  0.54
2015 Greiser M, Ward C, Lederer WJ. Stretch-Induced Changes in Atrial Ca Signaling Biophysical Journal. 108: 178a-179a. DOI: 10.1016/j.bpj.2014.11.986  0.345
2015 Greiser M, Ward C, Lederer WJ. Stretch-Induced Changes in Atrial Ca Signaling Biophysical Journal. 108: 178a-179a. DOI: 10.1016/j.bpj.2014.11.986  0.345
2015 Greiser M, Ward C, Lederer WJ. Stretch-Induced Changes in Atrial Ca Signaling Biophysical Journal. 108: 178a-179a. DOI: 10.1016/j.bpj.2014.11.986  0.345
2015 Hagen BM, Kao JP, Lederer WJ. In vivo Temperature Sensitivity of the Calcium Affinity of fluo-5F and mag-fluo4 Biophysical Journal. 108: 109a. DOI: 10.1016/j.bpj.2014.11.618  0.385
2015 Shukla S, Lederer WJ, Jafri MS. Analysis of ATP Production Efficiency of Beat-To-Beat Calcium Fluctuations in Cardiac Mitochondria Biophysical Journal. 108: 109a. DOI: 10.1016/J.Bpj.2014.11.617  0.572
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.541
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Garber L, Greiser M, Williams GS, Lederer WJ. Buffering Effects on the LCC Current and Spatiotemporal Ca2+ Dynamics Biophysical Journal. 108: 105a-106a. DOI: 10.1016/j.bpj.2014.11.601  0.347
2015 Wescott AP, Lederer W, Williams GS. Excitation-Metabolism Coupling in Mouse Heart Biophysical Journal. 108: 570a. DOI: 10.1016/j.bpj.2014.11.3117  0.389
2015 Brochet DX, Wang G, Lederer WJ, Cheng H. Calcium Signaling among RyR2s within a Calcium Release Unit during a Calcium Spark Biophysical Journal. 108: 568a. DOI: 10.1016/J.Bpj.2014.11.3108  0.606
2015 Previs MJ, Prosser BL, Mun JY, Beck Previs S, Gulick J, Lee K, Robbins J, Craig R, Lederer WJ, Warshaw DM. Myosin-Binding Protein C Corrects an Intrinsic Non-Uniformity in Cardiac Excitation-Contraction Coupling Biophysical Journal. 108: 362a. DOI: 10.1016/J.Bpj.2014.11.1984  0.468
2015 Previs MJ, Prosser BL, Mun JY, Beck Previs S, Gulick J, Lee K, Robbins J, Craig R, Lederer WJ, Warshaw DM. Myosin-Binding Protein C Corrects an Intrinsic Non-Uniformity in Cardiac Excitation-Contraction Coupling Biophysical Journal. 108: 362a. DOI: 10.1016/J.Bpj.2014.11.1984  0.468
2015 Hoang-Trong MT, Lederer WJ, Jafri MS. Cardiac Alternans Occurs through the Synergy of Voltage- and Calcium-Dependent Mechanisms Biophysical Journal. 108: 263a. DOI: 10.1016/J.Bpj.2014.11.1453  0.588
2014 Walker MA, Williams GS, Kohl T, Lehnart SE, Jafri MS, Greenstein JL, Lederer WJ, Winslow RL. Superresolution modeling of calcium release in the heart. Biophysical Journal. 107: 3018-29. PMID 25517166 DOI: 10.1016/J.Bpj.2014.11.003  0.611
2014 Greiser M, Kerfant BG, Williams GS, Voigt N, Harks E, Dibb KM, Giese A, Meszaros J, Verheule S, Ravens U, Allessie MA, Gammie JS, van der Velden J, Lederer WJ, Dobrev D, et al. Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytes. The Journal of Clinical Investigation. 124: 4759-72. PMID 25329692 DOI: 10.1172/Jci70102  0.6
2014 Boyman L, Chikando AC, Williams GS, Khairallah RJ, Kettlewell S, Ward CW, Smith GL, Kao JP, Lederer WJ. Calcium movement in cardiac mitochondria. Biophysical Journal. 107: 1289-301. PMID 25229137 DOI: 10.1016/J.Bpj.2014.07.045  0.605
2014 Ward CW, Prosser BL, Lederer WJ. Mechanical stretch-induced activation of ROS/RNS signaling in striated muscle. Antioxidants & Redox Signaling. 20: 929-36. PMID 23971496 DOI: 10.1089/ars.2013.5517  0.54
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/J.Bpj.2013.11.762  0.599
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Zhao G, Brochet DX, Li T, Rosenberg P, Lederer WJ. STIM1 Enhances SR Ca2+ Refilling through Activating SERCA2a in Rat Ventricular Myocytes Biophysical Journal. 106: 129a. DOI: 10.1016/j.bpj.2013.11.762  0.366
2014 Limbu S, Hoang-Trong TM, Prosser BL, Williams GS, Lederer WJ, Jafri MS. Mechanisms of Stretch-Activated Reactive Oxygen Modulation of Excitation-Contraction Coupling: Computational Studies Biophysical Journal. 106: 732a. DOI: 10.1016/J.Bpj.2013.11.4038  0.582
2014 Kerr JP, Prosser BL, Shi G, Becerra N, Lederer WJ, Raiteri R, Ward CW. Microtubule Network Density Tunes Both Stretch and Contraction Activated X-ROS Biophysical Journal. 106: 727a. DOI: 10.1016/J.Bpj.2013.11.4013  0.496
2014 Bamgboye MA, Lederer W. Ros in Cardiac Calcium Signaling Biophysical Journal. 106: 534a-535a. DOI: 10.1016/j.bpj.2013.11.2981  0.467
2014 Wescott AP, Lederer W, Williams GS. Modeling Mitochondrial Calcium Dynamics in Heart Biophysical Journal. 106: 534a. DOI: 10.1016/j.bpj.2013.11.2978  0.449
2014 Ullah A, Hoang Trong MT, Williams GS, Winslow RL, Lederer WJ, Jafri MS. Critical Requirements for the Initiation of a Cardiac Arrhythmia in Heart: Cell Number Biophysical Journal. 106: 431a. DOI: 10.1016/J.Bpj.2013.11.2427  0.533
2014 Brochet DX, Lederer WJ. Decomposition of a Calcium Spark in Cardiac Myocytes Biophysical Journal. 106: 430a. DOI: 10.1016/j.bpj.2013.11.2424  0.48
2014 Prosser BL, Ward CW, Kerr JP, Shi G, Lederer WJ. Stretch-Dependent Regulation of Calcium Signaling in Heart - Who are the Key Players? Biophysical Journal. 106: 322a. DOI: 10.1016/J.Bpj.2013.11.1858  0.557
2014 Hagen BM, Kao JP, Lederer WJ. Investigation of Arrhythmogenic Calcium Events by Initiating Local Calcium Release in Cardiomyocytes Biophysical Journal. 106: 321a. DOI: 10.1016/j.bpj.2013.11.1851  0.439
2014 Williams GS, Wescott AP, Lederer W, Jafri MS. Dynamics of Calcium Sparks and SR Calcium Leak During Excitation-Contraction Coupling in Mouse Heart Cells Biophysical Journal. 106: 320a-321a. DOI: 10.1016/J.Bpj.2013.11.1850  0.621
2013 Williams GS, Boyman L, Chikando AC, Khairallah RJ, Lederer WJ. Mitochondrial calcium uptake. Proceedings of the National Academy of Sciences of the United States of America. 110: 10479-86. PMID 23759742 DOI: 10.1073/Pnas.1300410110  0.606
2013 Lederer WJ. Superresolution imaging--caveolae, caveolins, mitochondria, and function in heart. Biophysical Journal. 104: 2323. PMID 23746501 DOI: 10.1016/j.bpj.2013.04.041  0.4
2013 Mannella CA, Lederer WJ, Jafri MS. The connection between inner membrane topology and mitochondrial function. Journal of Molecular and Cellular Cardiology. 62: 51-7. PMID 23672826 DOI: 10.1016/J.Yjmcc.2013.05.001  0.43
2013 Boyman L, Williams GS, Khananshvili D, Sekler I, Lederer WJ. NCLX: the mitochondrial sodium calcium exchanger. Journal of Molecular and Cellular Cardiology. 59: 205-13. PMID 23538132 DOI: 10.1016/j.yjmcc.2013.03.012  0.594
2013 Prosser BL, Ward CW, Lederer WJ. X-ROS signalling is enhanced and graded by cyclic cardiomyocyte stretch. Cardiovascular Research. 98: 307-14. PMID 23524301 DOI: 10.1093/Cvr/Cvt066  0.558
2013 Wei X, Li T, Hagen B, Zhang P, Sanchez PG, Williams K, Li S, Bianchi G, Son HS, Wu C, DeFilippi C, Xu K, Lederer WJ, Wu ZJ, Griffith BP. Short-term mechanical unloading with left ventricular assist devices after acute myocardial infarction conserves calcium cycling and improves heart function. Jacc. Cardiovascular Interventions. 6: 406-15. PMID 23523452 DOI: 10.1016/j.jcin.2012.12.122  0.504
2013 Lederer WJ, Bers DM, Eisner DA. Calcium signaling in heart: multiscale, diverse, rapid, local, and remarkable. Journal of Molecular and Cellular Cardiology. 58: 3-4. PMID 23500389 DOI: 10.1016/J.Yjmcc.2013.03.003  0.441
2013 Prosser BL, Khairallah RJ, Ziman AP, Ward CW, Lederer WJ. X-ROS signaling in the heart and skeletal muscle: stretch-dependent local ROS regulates [Ca²⁺]i. Journal of Molecular and Cellular Cardiology. 58: 172-81. PMID 23220288 DOI: 10.1016/J.Yjmcc.2012.11.011  0.562
2013 Wagner E, Kohl T, Tuan HTM, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ, Lehnart SE. Best Basic Science abstract Europace. 15: ii223-ii223. DOI: 10.1093/Europace/Eut179  0.563
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/Eurheartj/Eht307.34  0.517
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Lehnart SE, Wagner E, Kohl T, Westphal V, Parlitz U, Luther S, Hell SW, Jafri MS, Lederer WJ. Proliferative membrane changes of T-tubules and cell-wide network changes during cardiac remodeling with orphaning of Ca2+ release sites are a general mechanism of heart failure European Heart Journal. 34: 34-34. DOI: 10.1093/eurheartj/eht307.34  0.312
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.542
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Zhao G, Brochet DX, Lederer WJ. STIM1 Induces Ca2+ and Membrane Potential Oscillations Independent of SOCE in Rat Ventricular Myocytes Biophysical Journal. 104: 100a. DOI: 10.1016/j.bpj.2012.11.591  0.347
2013 Ward CW, Shi G, Prosser BL, Lederer W, Khairallah RJ. Increased Microtubule Network Stability Underlies X-ROS in Dystrophic Skeletal Muscle Biophysical Journal. 104: 616a. DOI: 10.1016/J.Bpj.2012.11.3409  0.458
2013 Williams GS, Boyman L, Chikando AC, Khairallah RJ, Lederer WJ. Mitochondrial Calcium Uptake: Context Matters Biophysical Journal. 104: 605a. DOI: 10.1016/J.Bpj.2012.11.3356  0.601
2013 Boyman L, Williams GS, Khairallah RJ, Chikando A, Hagen BM, Kettlewell S, Smith GL, Lederer WJ. Mitochondrial Ca2+ Dynamics in the Heart Biophysical Journal. 104: 605a. DOI: 10.1016/J.Bpj.2012.11.3355  0.599
2013 Boyman L, Williams GS, Khairallah RJ, Chikando A, Hagen BM, Kettlewell S, Smith GL, Lederer WJ. Mitochondrial Ca2+ Dynamics in the Heart Biophysical Journal. 104: 605a. DOI: 10.1016/j.bpj.2012.11.3355  0.35
2013 Brochet DX, Lederer WJ. Activation of RyR Clusters during a Calcium Spark in Cardiac Myocytes Biophysical Journal. 104: 438a. DOI: 10.1016/j.bpj.2012.11.2431  0.459
2013 Gondim AN, Cruz JS, Lederer W, Hagen BM. Dissecting the Calcium Transient Refractoriness in Mouse Ventricular Myocytes Biophysical Journal. 104: 436a-437a. DOI: 10.1016/j.bpj.2012.11.2426  0.464
2013 Chikando A, Boyman L, Khairallah R, Williams GS, Kettlewell S, Ward C, Smith GL, Kao J, Lederer WJ. ROS and Mitochondrial Membrane Potential Dependent Modulation of Calcium Signaling in the Heart Biophysical Journal. 104: 361a. DOI: 10.1016/J.Bpj.2012.11.2007  0.599
2012 Konstantinidis K, Lederer WJ, Rizzuto R, Kitsis RN. Mitofusin 2 joins the sarcoplasmic reticulum and mitochondria at the hip to sustain cardiac energetics. Circulation Research. 111: 821-3. PMID 22982869 DOI: 10.1161/Circresaha.112.277269  0.619
2012 Khairallah RJ, Shi G, Sbrana F, Prosser BL, Borroto C, Mazaitis MJ, Hoffman EP, Mahurkar A, Sachs F, Sun Y, Chen YW, Raiteri R, Lederer WJ, Dorsey SG, Ward CW. Microtubules underlie dysfunction in duchenne muscular dystrophy. Science Signaling. 5: ra56. PMID 22871609 DOI: 10.1126/Scisignal.2002829  0.496
2012 Wagner E, Lauterbach MA, Kohl T, Westphal V, Williams GS, Steinbrecher JH, Streich JH, Korff B, Tuan HT, Hagen B, Luther S, Hasenfuss G, Parlitz U, Jafri MS, Hell SW, ... Lederer WJ, et al. Stimulated emission depletion live-cell super-resolution imaging shows proliferative remodeling of T-tubule membrane structures after myocardial infarction. Circulation Research. 111: 402-14. PMID 22723297 DOI: 10.1161/Circresaha.112.274530  0.491
2012 Hagen BM, Boyman L, Kao JP, Lederer WJ. A comparative assessment of fluo Ca2+ indicators in rat ventricular myocytes. Cell Calcium. 52: 170-81. PMID 22721780 DOI: 10.1016/j.ceca.2012.05.010  0.556
2012 Lederer WJ, Hagen BM, Zhao G. Cell biology. Superresolution subspace signaling. Science (New York, N.Y.). 336: 546-7. PMID 22556238 DOI: 10.1126/science.1222540  0.363
2012 Brochet DX, Yang D, Cheng H, Lederer WJ. Elementary calcium release events from the sarcoplasmic reticulum in the heart. Advances in Experimental Medicine and Biology. 740: 499-509. PMID 22453956 DOI: 10.1007/978-94-007-2888-2_21  0.599
2012 Liu OZ, Lederer WJ, Sobie EA. Does the Goldilocks Principle apply to calcium release restitution in heart cells? Journal of Molecular and Cellular Cardiology. 52: 3-6. PMID 22056316 DOI: 10.1016/J.Yjmcc.2011.10.014  0.635
2012 Sobie EA, Lederer WJ. Dynamic local changes in sarcoplasmic reticulum calcium: physiological and pathophysiological roles. Journal of Molecular and Cellular Cardiology. 52: 304-11. PMID 21767546 DOI: 10.1016/J.Yjmcc.2011.06.024  0.59
2012 Tuan Hoang-Trong M, Williams GS, Lehnart SE, Lederer WJ, Jafri MS. Stochastic Simulation Assessing the Functional Changes Occurring during Heart Failure Biophysical Journal. 102: 101a. DOI: 10.1016/j.bpj.2011.11.571  0.386
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.562
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Brochet DX, Lederer WJ. Ca2+ Heterogeneity Within a Ca2+ Spark Biophysical Journal. 102: 100a. DOI: 10.1016/j.bpj.2011.11.569  0.377
2012 Chikando AC, Boyman L, Khairallah R, Ward C, Smith G, Kao J, Lederer W. ROS Dependent Modulation of Calcium Sparks in Cardiomyocytes Biophysical Journal. 102: 99a. DOI: 10.1016/J.Bpj.2011.11.563  0.596
2012 Khairallah RJ, Sbrana F, Shi G, Tedesco M, Prosser BL, Raiteri R, Lederer WJ, Ward CW. Microtubule Dependent Mechano-Transduction Drives Oxidative Stress and Calcium Dysregulation in Dystrophic Skeletal Muscle Biophysical Journal. 102: 424a. DOI: 10.1016/J.Bpj.2011.11.2319  0.47
2012 Boyman L, Hagen BM, Khairallah RJ, Chikando A, Kettlewell S, Smith GL, Lederer W. Dynamics of Calcium Uptake and Release by the Mitochondria in the Heart Biophysical Journal. 102: 312a. DOI: 10.1016/J.Bpj.2011.11.1717  0.602
2012 Kohl T, Parlitz U, Lauterbach M, Minh Tuan H, Williams GS, Westphal V, Jafri MS, Lederer W, Luther S, Hell SW, Lehnart SE. STED Nanoscopy of Cardiac RyR2 Clusters and Sub-Structure Analysis After Myocardial Infarction Biophysical Journal. 102: 305a. DOI: 10.1016/J.Bpj.2011.11.1683  0.433
2012 Prosser BL, Ward CW, Hagen B, Khairallah RJ, Lederer WJ. Stretch Dependent XROS Signaling: Rapid Mechanotransduction in Heart Biophysical Journal. 102: 227a. DOI: 10.1016/J.Bpj.2011.11.1248  0.589
2012 Hagen BM, Lederer W. Calcium Spark and Wave Behavior in the Intact Rat Heart Biophysical Journal. 102: 227a. DOI: 10.1016/j.bpj.2011.11.1246  0.428
2012 Wagner E, Lauterbach M, Kohl T, Westphal V, Williams GS, Steinbrecher JH, Streich J, Tuan HM, Hagen B, Luther S, Parlitz U, Jafri MS, Hell SW, Lederer W, Lehnart SE. Live Cell Super-Resolution Imaging of Transverse Membrane Tubules in Heart Failure Biophysical Journal. 102: 223a-224a. DOI: 10.1016/J.Bpj.2011.11.1227  0.553
2011 Tuan HT, Williams GS, Chikando AC, Sobie EA, Lederer WJ, Jafri MS. Stochastic simulation of cardiac ventricular myocyte calcium dynamics and waves. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 4677-80. PMID 22255381 DOI: 10.1109/IEMBS.2011.6091158  0.419
2011 Williams GS, Chikando AC, Tuan HT, Sobie EA, Lederer WJ, Jafri MS. Dynamics of calcium sparks and calcium leak in the heart. Biophysical Journal. 101: 1287-96. PMID 21943409 DOI: 10.1016/J.Bpj.2011.07.021  0.618
2011 Prosser BL, Ward CW, Lederer WJ. X-ROS signaling: rapid mechano-chemo transduction in heart. Science (New York, N.Y.). 333: 1440-5. PMID 21903813 DOI: 10.1126/Science.1202768  0.598
2011 Chikando AC, Kettlewell S, Williams GS, Smith G, Lederer WJ. Ca2+ dynamics in the mitochondria - state of the art. Journal of Molecular and Cellular Cardiology. 51: 627-31. PMID 21864537 DOI: 10.1016/J.Yjmcc.2011.08.003  0.602
2011 Ma D, Taneja TK, Hagen BM, Kim BY, Ortega B, Lederer WJ, Welling PA. Golgi export of the Kir2.1 channel is driven by a trafficking signal located within its tertiary structure. Cell. 145: 1102-15. PMID 21703452 DOI: 10.1016/J.Cell.2011.06.007  0.431
2011 Boyman L, Hagen BM, Giladi M, Hiller R, Lederer WJ, Khananshvili D. Proton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger. The Journal of Biological Chemistry. 286: 28811-20. PMID 21680748 DOI: 10.1074/jbc.M110.214106  0.577
2011 Maruyama M, Li BY, Chen H, Xu X, Song LS, Guatimosim S, Zhu W, Yong W, Zhang W, Bu G, Lin SF, Fishbein MC, Lederer WJ, Schild JH, Field LJ, et al. FKBP12 is a critical regulator of the heart rhythm and the cardiac voltage-gated sodium current in mice. Circulation Research. 108: 1042-52. PMID 21372286 DOI: 10.1161/Circresaha.110.237867  0.474
2011 Papanicolaou KN, Khairallah RJ, Ngoh GA, Chikando A, Luptak I, O'Shea KM, Riley DD, Lugus JJ, Colucci WS, Lederer WJ, Stanley WC, Walsh K. Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Molecular and Cellular Biology. 31: 1309-28. PMID 21245373 DOI: 10.1128/Mcb.00911-10  0.46
2011 Greiser M, Lederer WJ, Schotten U. Alterations of atrial Ca(2+) handling as cause and consequence of atrial fibrillation. Cardiovascular Research. 89: 722-33. PMID 21159669 DOI: 10.1093/cvr/cvq389  0.561
2011 Brochet DX, Xie W, Yang D, Cheng H, Lederer WJ. Quarky calcium release in the heart. Circulation Research. 108: 210-8. PMID 21148431 DOI: 10.1161/Circresaha.110.231258  0.587
2011 Rogers TB, Pati S, Gaa S, Riley D, Khakoo AY, Patel S, Wardlow RD, Frederick CA, Hall G, He LP, Lederer WJ. Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes. Journal of Molecular and Cellular Cardiology. 50: 346-56. PMID 20837021 DOI: 10.1016/J.Yjmcc.2010.09.001  0.529
2011 Williams GS, Chikando AC, Lederer WJ, Sobie EA, Tuan HM, Jafri MS. Ca2+ Leak and Ca2+ Sparks in Mammalian Heart: Insights from a Computational Model Biophysical Journal. 100: 557a. DOI: 10.1016/J.Bpj.2010.12.3238  0.625
2011 Williams GS, Chikando AC, Lederer WJ, Sobie EA, Tuan HM, Jafri MS. Ca2+ Leak and Ca2+ Sparks in Mammalian Heart: Insights from a Computational Model Biophysical Journal. 100: 557a. DOI: 10.1016/j.bpj.2010.12.3238  0.41
2011 Williams GS, Chikando AC, Lederer WJ, Sobie EA, Tuan HM, Jafri MS. Ca2+ Leak and Ca2+ Sparks in Mammalian Heart: Insights from a Computational Model Biophysical Journal. 100: 557a. DOI: 10.1016/j.bpj.2010.12.3238  0.41
2011 Williams GS, Chikando AC, Lederer WJ, Sobie EA, Tuan HM, Jafri MS. Ca2+ Leak and Ca2+ Sparks in Mammalian Heart: Insights from a Computational Model Biophysical Journal. 100: 557a. DOI: 10.1016/j.bpj.2010.12.3238  0.41
2011 Williams GS, Chikando AC, Lederer WJ, Sobie EA, Tuan HM, Jafri MS. Ca2+ Leak and Ca2+ Sparks in Mammalian Heart: Insights from a Computational Model Biophysical Journal. 100: 557a. DOI: 10.1016/j.bpj.2010.12.3238  0.41
2011 Williams GS, Chikando AC, Lederer WJ, Sobie EA, Tuan HM, Jafri MS. Ca2+ Leak and Ca2+ Sparks in Mammalian Heart: Insights from a Computational Model Biophysical Journal. 100: 557a. DOI: 10.1016/j.bpj.2010.12.3238  0.41
2011 Williams GS, Chikando AC, Lederer WJ, Sobie EA, Tuan HM, Jafri MS. Ca2+ Leak and Ca2+ Sparks in Mammalian Heart: Insights from a Computational Model Biophysical Journal. 100: 557a. DOI: 10.1016/j.bpj.2010.12.3238  0.41
2011 Chikando A, Kao JP, Lederer W. Effects of Mitochondrial Membrane Depolarization on Cellular Function in Cardiac Myocytes Biophysical Journal. 100: 555a. DOI: 10.1016/J.Bpj.2010.12.3228  0.541
2011 DeVere Riley D, Chikando AC, Lederer WJ. Glucose Provides Short-Term Protection to Mitochondria in Rat Ventricular Cardiac Myocytes Biophysical Journal. 100: 461a-462a. DOI: 10.1016/J.Bpj.2010.12.2713  0.433
2011 Khairallah RJ, Prosser BL, Lederer WJ, Ward CW. A Novel Assay of Muscle Energy Dynamics in Mechanically Loaded Enzymatically Isolated Adult Mammalian Skeletal Myocytes Biophysical Journal. 100: 460a. DOI: 10.1016/J.Bpj.2010.12.2706  0.457
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.548
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Boyman L, Hagen BM, Hiller R, Lederer WJ, Khananshvili D. The pH Sensitivity of the Cardiac Na+/Ca2+ Exchanger Depend on Calcium Binding Domains (CBD) of NCX1 Biophysical Journal. 100: 439a. DOI: 10.1016/j.bpj.2010.12.2585  0.356
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/J.Bpj.2010.12.2121  0.589
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/j.bpj.2010.12.2121  0.372
2011 Prosser BL, Ward CW, Lederer WJ. Stretch-Dependent ROS Production and Ca2+ Signaling in Single Cardiomyocytes Biophysical Journal. 100: 352a. DOI: 10.1016/J.Bpj.2010.12.2120  0.577
2011 Prosser BL, Ward CW, Lederer WJ. Stretch-Dependent ROS Production and Ca2+ Signaling in Single Cardiomyocytes Biophysical Journal. 100: 352a. DOI: 10.1016/j.bpj.2010.12.2120  0.341
2011 Prosser BL, Ward CW, Lederer WJ. Stretch-Dependent ROS Production and Ca2+ Signaling in Single Cardiomyocytes Biophysical Journal. 100: 352a. DOI: 10.1016/j.bpj.2010.12.2120  0.341
2011 Prosser BL, Ward CW, Lederer WJ. Stretch-Dependent ROS Production and Ca2+ Signaling in Single Cardiomyocytes Biophysical Journal. 100: 352a. DOI: 10.1016/j.bpj.2010.12.2120  0.341
2011 Zhao G, Lederer WJ. STIM1 in Rat Ventricular Myocytes Biophysical Journal. 100: 196a. DOI: 10.1016/j.bpj.2010.12.1288  0.39
2010 Goodall MH, Wardlow RD, Goldblum RR, Ziman A, Lederer WJ, Randall W, Rogers TB. Novel function of cardiac protein kinase D1 as a dynamic regulator of Ca2+ sensitivity of contraction. The Journal of Biological Chemistry. 285: 41686-700. PMID 21041300 DOI: 10.1074/Jbc.M110.179648  0.541
2010 Ziman AP, Ward CW, Rodney GG, Lederer WJ, Bloch RJ. Quantitative measurement of Ca²(+) in the sarcoplasmic reticulum lumen of mammalian skeletal muscle. Biophysical Journal. 99: 2705-14. PMID 20959112 DOI: 10.1016/J.Bpj.2010.08.032  0.554
2010 Santana LF, Cheng EP, Lederer WJ. How does the shape of the cardiac action potential control calcium signaling and contraction in the heart? Journal of Molecular and Cellular Cardiology. 49: 901-3. PMID 20850450 DOI: 10.1016/J.Yjmcc.2010.09.005  0.456
2010 Prosser BL, Ward CW, Lederer WJ. Subcellular Ca2+ signaling in the heart: the role of ryanodine receptor sensitivity. The Journal of General Physiology. 136: 135-42. PMID 20660656 DOI: 10.1085/Jgp.201010406  0.611
2010 Ramay HR, Jafri MS, Lederer WJ, Sobie EA. Predicting local SR Ca(2+) dynamics during Ca(2+) wave propagation in ventricular myocytes. Biophysical Journal. 98: 2515-23. PMID 20513395 DOI: 10.1016/J.Bpj.2010.02.038  0.583
2010 Santiago DJ, Curran JW, Bers DM, Lederer WJ, Stern MD, Ríos E, Shannon TR. Ca sparks do not explain all ryanodine receptor-mediated SR Ca leak in mouse ventricular myocytes. Biophysical Journal. 98: 2111-20. PMID 20483318 DOI: 10.1016/J.Bpj.2010.01.042  0.602
2010 Josephson IR, Guia A, Sobie EA, Lederer WJ, Lakatta EG, Stern MD. Physiologic gating properties of unitary cardiac L-type Ca2+ channels. Biochemical and Biophysical Research Communications. 396: 763-6. PMID 20457123 DOI: 10.1016/J.Bbrc.2010.05.016  0.608
2010 Lehnart SE, Lederer WJ. An antidote for calcium leak: targeting molecular arrhythmia mechanisms. Journal of Molecular and Cellular Cardiology. 48: 279-82. PMID 19931542 DOI: 10.1016/j.yjmcc.2009.11.005  0.393
2010 Josephson IR, Guia A, Lakatta EG, Lederer WJ, Stern MD. Ca(2+)-dependent components of inactivation of unitary cardiac L-type Ca(2+) channels. The Journal of Physiology. 588: 213-23. PMID 19917566 DOI: 10.1113/jphysiol.2009.178343  0.615
2010 Ziman AP, Gómez-Viquez NL, Bloch RJ, Lederer WJ. Excitation-contraction coupling changes during postnatal cardiac development. Journal of Molecular and Cellular Cardiology. 48: 379-86. PMID 19818794 DOI: 10.1016/J.Yjmcc.2009.09.016  0.474
2010 He L, Zhao G, Wier WG, Lederer WJ. Cylic AMP Measured with ICUE3 in Vascular Smooth Muscle Cells Biophysical Journal. 98: 101a. DOI: 10.1016/j.bpj.2009.12.563  0.369
2010 DeVere Riley D, Rogers TB, Khakoo AY, Frederick CA, Pati S, Gaa SA, Lederer WJ. Mesenchymal Stem Cells Protect Cardiomyocytes Biophysical Journal. 98: 718a. DOI: 10.1016/J.Bpj.2009.12.3934  0.489
2010 Ziman AP, Ackermann MA, Lederer W, Bloch RJ. Small Ankyrin 1 Organizes the Ca2+ Stores of the Sarcoplasmic Reticulum in Skeletal Muscle Biophysical Journal. 98: 713a. DOI: 10.1016/J.Bpj.2009.12.3912  0.573
2010 Ziman AP, Ackermann MA, Lederer W, Bloch RJ. Small Ankyrin 1 Organizes the Ca2+ Stores of the Sarcoplasmic Reticulum in Skeletal Muscle Biophysical Journal. 98: 713a. DOI: 10.1016/J.Bpj.2009.12.3912  0.573
2010 Zhao G, Lederer WJ. Mitochondria Function in Arterial Smooth Muscle Cells Biophysical Journal. 98: 377a. DOI: 10.1016/j.bpj.2009.12.2034  0.373
2010 Chikando AC, Khairallah R, Stanley W, Lederer WJ. Effects of Dietary Lipids on Stress-Dependent Depolarization of Cardiac Mitochondrial Membrane Biophysical Journal. 98: 362a. DOI: 10.1016/J.Bpj.2009.12.1949  0.448
2010 Bamgboye MA, Lederer W. Calcium Dynamics in Cardiac Mitochondria Biophysical Journal. 98: 298a. DOI: 10.1016/j.bpj.2009.12.1621  0.465
2010 Prosser BL, Ward CW, Lederer W. Single Cell Measurements of Isometric Force and Cytosolic Calcium in Intact Mammalian Cardiomyocytes Biophysical Journal. 98: 201a. DOI: 10.1016/j.bpj.2009.12.1074  0.435
2009 Salnikov V, Lukyanenko YO, Lederer WJ, Lukyanenko V. Distribution of ryanodine receptors in rat ventricular myocytes. Journal of Muscle Research and Cell Motility. 30: 161-70. PMID 19707881 DOI: 10.1007/s10974-009-9186-9  0.563
2009 Lukyanenko V, Chikando A, Lederer WJ. Mitochondria in cardiomyocyte Ca2+ signaling. The International Journal of Biochemistry & Cell Biology. 41: 1957-71. PMID 19703657 DOI: 10.1016/j.biocel.2009.03.011  0.62
2009 Trafford AW, Lederer WJ, Sobie EA. Keeping the beat: life without SERCA--is it possible? Journal of Molecular and Cellular Cardiology. 47: 171-3. PMID 19460389 DOI: 10.1016/J.Yjmcc.2009.05.005  0.538
2009 Lindegger N, Hagen BM, Marks AR, Lederer WJ, Kass RS. Diastolic transient inward current in long QT syndrome type 3 is caused by Ca2+ overload and inhibited by ranolazine. Journal of Molecular and Cellular Cardiology. 47: 326-34. PMID 19371746 DOI: 10.1016/J.Yjmcc.2009.04.003  0.724
2009 Iribe G, Ward CW, Camelliti P, Bollensdorff C, Mason F, Burton RA, Garny A, Morphew MK, Hoenger A, Lederer WJ, Kohl P. Axial stretch of rat single ventricular cardiomyocytes causes an acute and transient increase in Ca2+ spark rate. Circulation Research. 104: 787-95. PMID 19197074 DOI: 10.1161/Circresaha.108.193334  0.574
2009 Dobrev D, Teos LY, Lederer WJ. Unique atrial myocyte Ca2+ signaling. Journal of Molecular and Cellular Cardiology. 46: 448-51. PMID 19150353 DOI: 10.1016/j.yjmcc.2008.12.004  0.567
2009 Bamgboye MA, Altamirano J, Lederer WJ. Tracking Membrane Potential, Calcium and REDOX Activity in Single Mitochondria During Normal Cardiac Cell Stimulation Biophysical Journal. 96: 625a. DOI: 10.1016/J.Bpj.2008.12.3304  0.579
2009 Goodall MH, Teos LY, Goldblum RR, Ziman A, William Bell Hd, Lederer WJ, Randall W, Rogers TB. Novel Functions of Protein Kinase D in Cardiac Excitation-Contraction Coupling Biophysical Journal. 96: 622a-623a. DOI: 10.1016/J.Bpj.2008.12.3290  0.599
2009 Lehnart SE, Ward CW, Sobie EA, Lederer W. Mutant Ryanodine Receptor-dependent Calcium Leak, RyR2 Open Probability, Calcium Sparks And Cardiac Arrhythmogenesis Biophysical Journal. 96: 550a. DOI: 10.1016/J.Bpj.2008.12.2981  0.571
2009 Ziman AP, Ward C, Rodney G, Hartford A, Lederer W, Bloch RJ. Dynamic Measurements of Luminal Ca2+ in the SR of Mammalian Skeletal Muscle Biophysical Journal. 96: 540a-541a. DOI: 10.1016/J.Bpj.2008.12.2792  0.58
2009 Ziman AP, Ward C, Rodney G, Hartford A, Lederer W, Bloch RJ. Dynamic Measurements of Luminal Ca2+ in the SR of Mammalian Skeletal Muscle Biophysical Journal. 96: 540a-541a. DOI: 10.1016/j.bpj.2008.12.2792  0.308
2009 Ziman AP, Ward C, Rodney G, Hartford A, Lederer W, Bloch RJ. Dynamic Measurements of Luminal Ca2+ in the SR of Mammalian Skeletal Muscle Biophysical Journal. 96: 540a-541a. DOI: 10.1016/j.bpj.2008.12.2792  0.308
2009 Ziman AP, Ward C, Rodney G, Hartford A, Lederer W, Bloch RJ. Dynamic Measurements of Luminal Ca2+ in the SR of Mammalian Skeletal Muscle Biophysical Journal. 96: 540a-541a. DOI: 10.1016/j.bpj.2008.12.2792  0.308
2009 Altamirano J, Lederer WJ. Beta-Adrenergic Stimulation Does Not Affect Calcium Sparks Refractoriness in Ventricular Myocytes Biophysical Journal. 96: 276a. DOI: 10.1016/J.Bpj.2008.12.1366  0.592
2009 Hagen BM, Ni J, Kao JP, Lederer WJ. Origin And Propagation Velocity Of Ca2+ Waves Determine The Kinetics Of Transient Inward Currents (Iti) In Cardiomyocytes Biophysical Journal. 96: 274a. DOI: 10.1016/j.bpj.2008.12.1357  0.501
2009 DeVere Riley D, Lederer WJ. Acute effects of Lipopolysaccharide on L-type Ca2+ channel currents and Transient Outward K+ channel currents in Rat Ventricular Myocytes Biophysical Journal. 96: 259a. DOI: 10.1016/j.bpj.2008.12.1278  0.506
2009 Brochet DX, Yang D, Xie W, Cheng H, Lederer W. Quarky Calcium Sparks in Heart Biophysical Journal. 96: 21a-22a. DOI: 10.1016/J.Bpj.2008.12.1014  0.589
2008 Cheng H, Lederer WJ. Calcium sparks. Physiological Reviews. 88: 1491-545. PMID 18923188 DOI: 10.1152/physrev.00030.2007  0.613
2008 van Oort RJ, Altamirano J, Lederer WJ, Wehrens XH. Alternative splicing: a key mechanism for ankyrin-B functional diversity? Journal of Molecular and Cellular Cardiology. 45: 709-11. PMID 18838078 DOI: 10.1016/J.Yjmcc.2008.08.016  0.447
2008 Hund TJ, Ziman AP, Lederer WJ, Mohler PJ. The cardiac IP3 receptor: uncovering the role of "the other" calcium-release channel. Journal of Molecular and Cellular Cardiology. 45: 159-61. PMID 18598702 DOI: 10.1016/J.Yjmcc.2008.06.001  0.639
2008 Boyman L, Hiller R, Lederer WJ, Khananshvili D. Direct Loading of the purified endogenous inhibitor into the cytoplasm of patched cardiomyocytes blocks the ion currents and calcium transport through the NCX1 protein. Biochemistry. 47: 6602-11. PMID 18507397 DOI: 10.1021/bi8004279  0.62
2008 Kass RS, Lindegger N, Hagen B, Lederer WJ. Another calcium paradox in heart failure. Journal of Molecular and Cellular Cardiology. 45: 28-31. PMID 18504047 DOI: 10.1016/j.yjmcc.2008.04.001  0.586
2008 Lehnart SE, Mongillo M, Bellinger A, Lindegger N, Chen BX, Hsueh W, Reiken S, Wronska A, Drew LJ, Ward CW, Lederer WJ, Kass RS, Morley G, Marks AR. Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. The Journal of Clinical Investigation. 118: 2230-45. PMID 18483626 DOI: 10.1172/Jci35346  0.648
2008 Guatimosim S, Amaya MJ, Guerra MT, Aguiar CJ, Goes AM, Gómez-Viquez NL, Rodrigues MA, Gomes DA, Martins-Cruz J, Lederer WJ, Leite MF. Nuclear Ca2+ regulates cardiomyocyte function. Cell Calcium. 44: 230-42. PMID 18201761 DOI: 10.1016/j.ceca.2007.11.016  0.592
2008 Navedo MF, Nieves-Cintrón M, Amberg GC, Yuan C, Votaw VS, Lederer WJ, McKnight GS, Santana LF. AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension. Circulation Research. 102: e1-e11. PMID 18174462 DOI: 10.1161/Circresaha.107.167809  0.571
2007 Lehnart SE, Ackerman MJ, Benson DW, Brugada R, Clancy CE, Donahue JK, George AL, Grant AO, Groft SC, January CT, Lathrop DA, Lederer WJ, Makielski JC, Mohler PJ, Moss A, et al. Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation. 116: 2325-45. PMID 17998470 DOI: 10.1161/Circulationaha.107.711689  0.445
2007 Lukyanenko V, Ziman A, Lukyanenko A, Salnikov V, Lederer WJ. Functional groups of ryanodine receptors in rat ventricular cells. The Journal of Physiology. 583: 251-69. PMID 17627991 DOI: 10.1113/Jphysiol.2007.136549  0.609
2007 Györke S, Hagen BM, Terentyev D, Lederer WJ. Chain-reaction Ca(2+) signaling in the heart. The Journal of Clinical Investigation. 117: 1758-62. PMID 17607353 DOI: 10.1172/JCI32496  0.605
2007 Ruknudin AM, Wei SK, Haigney MC, Lederer WJ, Schulze DH. Phosphorylation and other conundrums of Na/Ca exchanger, NCX1. Annals of the New York Academy of Sciences. 1099: 103-18. PMID 17446449 DOI: 10.1196/annals.1387.036  0.511
2007 Sobie EA, Kao JP, Lederer WJ. Novel approach to real-time flash photolysis and confocal [Ca2+] imaging. Pflã¼Gers Archiv : European Journal of Physiology. 454: 663-73. PMID 17323075 DOI: 10.1007/S00424-007-0229-Z  0.541
2007 Salnikov V, Lukyánenko YO, Frederick CA, Lederer WJ, Lukyánenko V. Probing the outer mitochondrial membrane in cardiac mitochondria with nanoparticles. Biophysical Journal. 92: 1058-71. PMID 17098804 DOI: 10.1529/biophysj.106.094318  0.447
2007 Chandler N, Inada S, Rogers T, Wang Y, Lederer W, Hartmann H, Boyett M, Dobrzynski H. Expression of dephosphorylated CX43 in transgenic mice hearts following acute activation of c-Jun N-terminal kinase Journal of Molecular and Cellular Cardiology. 42: S46. DOI: 10.1016/j.yjmcc.2007.03.130  0.366
2006 Sobie EA, Song LS, Lederer WJ. Restitution of Ca(2+) release and vulnerability to arrhythmias. Journal of Cardiovascular Electrophysiology. 17: S64-S70. PMID 16686684 DOI: 10.1111/J.1540-8167.2006.00385.X  0.6
2006 Lehnart SE, Terrenoire C, Reiken S, Wehrens XH, Song LS, Tillman EJ, Mancarella S, Coromilas J, Lederer WJ, Kass RS, Marks AR. Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proceedings of the National Academy of Sciences of the United States of America. 103: 7906-10. PMID 16672364 DOI: 10.1073/Pnas.0602133103  0.717
2006 Song LS, Sobie EA, McCulle S, Lederer WJ, Balke CW, Cheng H. Orphaned ryanodine receptors in the failing heart. Proceedings of the National Academy of Sciences of the United States of America. 103: 4305-10. PMID 16537526 DOI: 10.1073/Pnas.0509324103  0.604
2006 Josephson IR, Lederer WJ, Hartmann HA. Letter regarding article by Darbar et al, "unmasking of Brugada syndrome by lithium". Circulation. 113: e408; author reply e. PMID 16534022 DOI: 10.1161/CIRCULATIONAHA.105.596262  0.311
2006 Sobie EA, Guatimosim S, Gómez-Viquez L, Song LS, Hartmann H, Saleet Jafri M, Lederer WJ. The Ca 2+ leak paradox and rogue ryanodine receptors: SR Ca 2+ efflux theory and practice. Progress in Biophysics and Molecular Biology. 90: 172-85. PMID 16326215 DOI: 10.1016/J.Pbiomolbio.2005.06.010  0.619
2006 Parfenov AS, Salnikov V, Lederer WJ, Lukyánenko V. Aqueous diffusion pathways as a part of the ventricular cell ultrastructure. Biophysical Journal. 90: 1107-19. PMID 16284268 DOI: 10.1529/biophysj.105.071787  0.407
2006 Chandler N, Hartmann H, Rogers T, Lederer W, Wang Y, Boyett M, Dobrzynski H. Expression of connexin43 in the hearts of temporally regulated c-Jun N-terminal kinase transgenic mice Journal of Molecular and Cellular Cardiology. 40: 942. DOI: 10.1016/j.yjmcc.2006.03.074  0.368
2006 Iribe G, Ward CW, Camelliti P, Lederer WJ, Kohl P. AB23-2 Heart Rhythm. 3: S47. DOI: 10.1016/J.Hrthm.2006.02.155  0.308
2005 Santana LF, Núñez-Durán H, Dilly KW, Lederer WJ. Sodium current and arrhythmogenesis in heart failure. Heart Failure Clinics. 1: 193-205. PMID 17386846 DOI: 10.1016/J.Hfc.2005.06.003  0.516
2005 Song LS, Guatimosim S, Gómez-Viquez L, Sobie EA, Ziman A, Hartmann H, Lederer WJ. Calcium biology of the transverse tubules in heart. Annals of the New York Academy of Sciences. 1047: 99-111. PMID 16093488 DOI: 10.1196/Annals.1341.009  0.619
2005 Song LS, Pi Y, Kim SJ, Yatani A, Guatimosim S, Kudej RK, Zhang Q, Cheng H, Hittinger L, Ghaleh B, Vatner DE, Lederer WJ, Vatner SF. Paradoxical cellular Ca2+ signaling in severe but compensated canine left ventricular hypertrophy. Circulation Research. 97: 457-64. PMID 16051885 DOI: 10.1161/01.Res.0000179722.79295.D4  0.605
2005 Ward CW, Lederer WJ. Ghost sparks. Nature Cell Biology. 7: 457-9. PMID 15867931 DOI: 10.1038/ncb0505-457  0.425
2005 Knot HJ, Laher I, Sobie EA, Guatimosim S, Gomez-Viquez L, Hartmann H, Song LS, Lederer WJ, Graier WF, Malli R, Frieden M, Petersen OH. Twenty years of calcium imaging: cell physiology to dye for. Molecular Interventions. 5: 112-27. PMID 15821159 DOI: 10.1124/Mi.5.2.8  0.557
2005 Sobie EA, Song LS, Lederer WJ. Local recovery of Ca2+ release in rat ventricular myocytes. The Journal of Physiology. 565: 441-7. PMID 15817631 DOI: 10.1113/Jphysiol.2005.086496  0.619
2005 Zhang R, Khoo MS, Wu Y, Yang Y, Grueter CE, Ni G, Price EE, Thiel W, Guatimosim S, Song LS, Madu EC, Shah AN, Vishnivetskaya TA, Atkinson JB, Gurevich VV, ... ... Lederer WJ, et al. Calmodulin kinase II inhibition protects against structural heart disease. Nature Medicine. 11: 409-17. PMID 15793582 DOI: 10.1038/Nm1215  0.514
2005 Brochet DX, Yang D, Di Maio A, Lederer WJ, Franzini-Armstrong C, Cheng H. Ca2+ blinks: rapid nanoscopic store calcium signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 3099-104. PMID 15710901 DOI: 10.1073/Pnas.0500059102  0.603
2004 Lederer WJ, Guatimosim S, Song LS, Sobie EA, Hartmann H, Lukyanenko V. Ca2+ sparks in heart muscle Journal of Muscle Research and Cell Motility. 25: 602-603. PMID 16118853  0.557
2004 Dilly KW, Kurokawa J, Terrenoire C, Reiken S, Lederer WJ, Marks AR, Kass RS. Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization. The Journal of Biological Chemistry. 279: 40778-87. PMID 15272004 DOI: 10.1074/Jbc.M406010200  0.587
2003 Wehrens XH, Lehnart SE, Huang F, Vest JA, Reiken SR, Mohler PJ, Sun J, Guatimosim S, Song LS, Rosemblit N, D'Armiento JM, Napolitano C, Memmi M, Priori SG, Lederer WJ, et al. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell. 113: 829-40. PMID 12837242 DOI: 10.1016/S0092-8674(03)00434-3  0.527
2003 Schulze DH, Muqhal M, Lederer WJ, Ruknudin AM. Sodium/calcium exchanger (NCX1) macromolecular complex. The Journal of Biological Chemistry. 278: 28849-55. PMID 12754202 DOI: 10.1074/jbc.M300754200  0.442
2003 Sobie EA, Guatimosim S, Song LS, Lederer WJ. The challenge of molecular medicine: complexity versus Occam's razor. The Journal of Clinical Investigation. 111: 801-3. PMID 12639985 DOI: 10.1172/Jci18153  0.331
2003 Mohler PJ, Schott JJ, Gramolini AO, Dilly KW, Guatimosim S, duBell WH, Song LS, Haurogné K, Kyndt F, Ali ME, Rogers TB, Lederer WJ, Escande D, Le Marec H, Bennett V. Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature. 421: 634-9. PMID 12571597 DOI: 10.1038/Nature01335  0.455
2003 Reiken S, Gaburjakova M, Guatimosim S, Gomez AM, D'Armiento J, Burkhoff D, Wang J, Vassort G, Lederer WJ, Marks AR. Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol. The Journal of Biological Chemistry. 278: 444-53. PMID 12401811 DOI: 10.1074/Jbc.M207028200  0.479
2003 Zhang H, Noble D, Cannell M, Orchard CH, Lancaster M, Jones SA, Boyett MR, Holden AV, Jafri MS, Sobie EA, Lederer WJ, Demir SS, Michailova A, Delprincipe F, Egger M, et al. Dynamics of cardiac intracellular Ca2+ handling - From experiments to virtual cells International Journal of Bifurcation and Chaos in Applied Sciences and Engineering. 13: 3535-3560. DOI: 10.1142/S0218127403008843  0.683
2002 Choi KM, Zhong Y, Hoit BD, Grupp IL, Hahn H, Dilly KW, Guatimosim S, Lederer WJ, Matlib MA. Defective intracellular Ca(2+) signaling contributes to cardiomyopathy in Type 1 diabetic rats. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1398-408. PMID 12234790 DOI: 10.1152/Ajpheart.00313.2002  0.572
2002 Guatimosim S, Dilly K, Santana LF, Saleet Jafri M, Sobie EA, Lederer WJ. Local Ca(2+) signaling and EC coupling in heart: Ca(2+) sparks and the regulation of the [Ca(2+)](i) transient. Journal of Molecular and Cellular Cardiology. 34: 941-50. PMID 12234764 DOI: 10.1006/Jmcc.2002.2032  0.614
2002 Sobie EA, Dilly KW, dos Santos Cruz J, Lederer WJ, Jafri MS. Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release. Biophysical Journal. 83: 59-78. PMID 12080100 DOI: 10.1016/S0006-3495(02)75149-7  0.6
2002 duBell WH, Gigena MS, Guatimosim S, Long X, Lederer WJ, Rogers TB. Effects of PP1/PP2A inhibitor calyculin A on the E-C coupling cascade in murine ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 282: H38-48. PMID 11748045 DOI: 10.1152/Ajpheart.00536.2001  0.614
2001 Wellman GC, Cartin L, Eckman DM, Stevenson AS, Saundry CM, Lederer WJ, Nelson MT. Membrane depolarization, elevated Ca(2+) entry, and gene expression in cerebral arteries of hypertensive rats. American Journal of Physiology. Heart and Circulatory Physiology. 281: H2559-67. PMID 11709423 DOI: 10.1152/Ajpheart.2001.281.6.H2559  0.532
2001 Gómez AM, Guatimosim S, Dilly KW, Vassort G, Lederer WJ. Heart failure after myocardial infarction: altered excitation-contraction coupling. Circulation. 104: 688-93. PMID 11489776 DOI: 10.1161/Hc3201.092285  0.611
2001 Ufret-Vincenty CA, Baro DJ, Lederer WJ, Rockman HA, Quinones LE, Santana LF. Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure. The Journal of Biological Chemistry. 276: 28197-203. PMID 11369778 DOI: 10.1074/Jbc.M102548200  0.494
2001 Guatimosim S, Sobie EA, dos Santos Cruz J, Martin LA, Lederer WJ. Molecular identification of a TTX-sensitive Ca(2+) current. American Journal of Physiology. Cell Physiology. 280: C1327-39. PMID 11287346 DOI: 10.1152/Ajpcell.2001.280.5.C1327  0.614
2000 Ruknudin A, He S, Lederer WJ, Schulze DH. Functional differences between cardiac and renal isoforms of the rat Na+-Ca2+ exchanger NCX1 expressed in Xenopus oocytes. The Journal of Physiology. 529: 599-610. PMID 11118492 DOI: 10.1111/j.1469-7793.2000.00599.x  0.572
2000 Esposito G, Santana LF, Dilly K, Cruz JD, Mao L, Lederer WJ, Rockman HA. Cellular and functional defects in a mouse model of heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 279: H3101-12. PMID 11087268 DOI: 10.1152/Ajpheart.2000.279.6.H3101  0.515
2000 DuBell WH, Lederer WJ, Rogers TB. K(+) currents responsible for repolarization in mouse ventricle and their modulation by FK-506 and rapamycin. American Journal of Physiology. Heart and Circulatory Physiology. 278: H886-97. PMID 10710358 DOI: 10.1152/Ajpheart.2000.278.3.H886  0.419
2000 Jaggar JH, Porter VA, Lederer WJ, Nelson MT. Calcium sparks in smooth muscle. American Journal of Physiology. Cell Physiology. 278: C235-56. PMID 10666018 DOI: 10.1152/Ajpcell.2000.278.2.C235  0.584
1999 Blaustein MP, Lederer WJ. Sodium/calcium exchange: its physiological implications. Physiological Reviews. 79: 763-854. PMID 10390518  0.593
1999 Egger M, Ruknudin A, Niggli E, Lederer WJ, Schulze DH. Ni2+ transport by the human Na+/Ca2+ exchanger expressed in Sf9 cells. The American Journal of Physiology. 276: C1184-92. PMID 10329968 DOI: 10.1152/Ajpcell.1999.276.5.C1184  0.549
1999 Egger M, Ruknudin A, Lipp P, Kofuji P, Lederer WJ, Schulze DH, Niggli E. Functional expression of the human cardiac Na+/Ca2+ exchanger in Sf9 cells: rapid and specific Ni2+ transport. Cell Calcium. 25: 9-17. PMID 10191956 DOI: 10.1054/Ceca.1998.0002  0.578
1999 Zheng JS, Dai Y, Li J, Long X, O'Neill L, Li Z, Lederer WJ, Cheng H, Baum BJ, Lakatta EG, Crow MT, Boluyt MO. Expression of aquaporin-1 (AQP-1) in rat heart Asia Pacific Heart Journal. 8: 36-43. DOI: 10.1016/S1328-0163(99)90007-6  0.426
1998 Porter VA, Bonev AD, Knot HJ, Heppner TJ, Stevenson AS, Kleppisch T, Lederer WJ, Nelson MT. Frequency modulation of Casparks is involved in regulation of arterial diameter by cyclic nucleotides. American Journal of Physiology. Cell Physiology. 274: C1346-C1355. PMID 29591068 DOI: 10.1152/ajpcell.1998.274.5.C1346  0.334
1998 Drago GA, Colyer J, Lederer WJ. Immunofluorescence localization of SERCA2a and the phosphorylated forms of phospholamban in intact rat cardiac ventricular myocytes. Annals of the New York Academy of Sciences. 853: 273-9. PMID 10603958  0.428
1998 Jaggar JH, Wellman GC, Heppner TJ, Porter VA, Perez GJ, Gollasch M, Kleppisch T, Rubart M, Stevenson AS, Lederer WJ, Knot HJ, Bonev AD, Nelson MT. Ca2+ channels, ryanodine receptors and Ca(2+)-activated K+ channels: a functional unit for regulating arterial tone. Acta Physiologica Scandinavica. 164: 577-87. PMID 9887980 DOI: 10.1046/J.1365-201X.1998.00462.X  0.605
1998 duBell WH, Gaa ST, Lederer WJ, Rogers TB. Independent inhibition of calcineurin and K+ currents by the immunosuppressant FK-506 in rat ventricle. The American Journal of Physiology. 275: H2041-52. PMID 9843803 DOI: 10.1152/Ajpheart.1998.275.6.H2041  0.517
1998 Wessely R, Klingel K, Santana LF, Dalton N, Hongo M, Lederer WJ, Kandolf R, Knowlton KU. Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy Journal of Clinical Investigation. 102: 1444-1453. PMID 9769337 DOI: 10.1172/Jci1972  0.441
1998 Smith GD, Keizer JE, Stern MD, Lederer WJ, Cheng H. A simple numerical model of calcium spark formation and detection in cardiac myocytes. Biophysical Journal. 75: 15-32. PMID 9649364 DOI: 10.1016/S0006-3495(98)77491-0  0.598
1998 He S, Ruknudin A, Bambrick LL, Lederer WJ, Schulze DH. Isoform-specific regulation of the Na+/Ca2+ exchanger in rat astrocytes and neurons by PKA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4833-41. PMID 9634549  0.493
1998 Phillips RM, Narayan P, Gómez AM, Dilly K, Jones LR, Lederer WJ, Altschuld RA. Sarcoplasmic reticulum in heart failure: central player or bystander? Cardiovascular Research. 37: 346-51. PMID 9614491 DOI: 10.1016/S0008-6363(97)00260-5  0.613
1998 Porter VA, Bonev AD, Knot HJ, Heppner TJ, Stevenson AS, Kleppisch T, Lederer WJ, Nelson MT. Frequency modulation of Ca2+ sparks is involved in regulation of arterial diameter by cyclic nucleotides. The American Journal of Physiology. 274: C1346-55. PMID 9612222 DOI: 10.1152/Ajpcell.1998.274.5.C1346  0.587
1998 Ruknudin A, Schulze DH, Sullivan SK, Lederer WJ, Welling PA. Novel subunit composition of a renal epithelial KATP channel. The Journal of Biological Chemistry. 273: 14165-71. PMID 9603917 DOI: 10.1074/Jbc.273.23.14165  0.396
1998 Santana LF, Gómez AM, Lederer WJ. Ca2+ flux through promiscuous cardiac Na+ channels: slip-mode conductance. Science (New York, N.Y.). 279: 1027-33. PMID 9461434 DOI: 10.1126/Science.279.5353.1027  0.53
1997 Santana LF, Gómez AM, Kranias EG, Lederer WJ. Amount of calcium in the sarcoplasmic reticulum: influence on excitation-contraction coupling in heart muscle. Heart and Vessels. 44-9. PMID 9476542  0.617
1997 Santana LF, Kranias EG, Lederer WJ. Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes. The Journal of Physiology. 503: 21-9. PMID 9288671 DOI: 10.1111/J.1469-7793.1997.021Bi.X  0.591
1997 Ruknudin A, Valdivia C, Kofuji P, Lederer WJ, Schulze DH. Na+/Ca2+ exchanger in Drosophila: cloning, expression, and transport differences. The American Journal of Physiology. 273: C257-65. PMID 9252464 DOI: 10.1152/Ajpcell.1997.273.1.C257  0.558
1997 duBell WH, Wright PA, Lederer WJ, Rogers TB. Effect of the immunosupressant FK506 on excitation-contraction coupling and outward K+ currents in rat ventricular myocytes. The Journal of Physiology. 501: 509-16. PMID 9218211 DOI: 10.1111/J.1469-7793.1997.509Bm.X  0.597
1997 Li Z, Cheng H, Lederer WJ, Froehlich J, Lakatta EG. Enhanced proliferation and migration and altered cytoskeletal proteins in early passage smooth muscle cells from young and old rat aortic explants. Experimental and Molecular Pathology. 64: 1-11. PMID 9203504 DOI: 10.1006/Exmp.1997.2204  0.385
1997 Bénitah JP, Gómez AM, Delgado C, Lorente P, Lederer WJ. A chloride current component induced by hypertrophy in rat ventricular myocytes. The American Journal of Physiology. 272: H2500-6. PMID 9176322  0.412
1997 Gómez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, McCune SA, Altschuld RA, Lederer WJ. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science (New York, N.Y.). 276: 800-6. PMID 9115206 DOI: 10.1126/Science.276.5313.800  0.509
1997 Xiao YF, Gomez AM, Morgan JP, Lederer WJ, Leaf A. Suppression of voltage-gated L-type Ca2+ currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes. Proceedings of the National Academy of Sciences of the United States of America. 94: 4182-7. PMID 9108126 DOI: 10.1073/pnas.94.8.4182  0.58
1996 Lacampagne A, Lederer WJ, Schneider MF, Klein MG. Repriming and activation alter the frequency of stereotyped discrete Ca2+ release events in frog skeletal muscle. The Journal of Physiology. 497: 581-8. PMID 9003545 DOI: 10.1113/Jphysiol.1996.Sp021791  0.58
1996 Gómez AM, Cheng H, Lederer WJ, Bers DM. Ca2+ diffusion and sarcoplasmic reticulum transport both contribute to [Ca2+]i decline during Ca2+ sparks in rat ventricular myocytes. The Journal of Physiology. 496: 575-81. PMID 8910239 DOI: 10.1113/Jphysiol.1996.Sp021708  0.577
1996 Cheng H, Lederer MR, Xiao RP, Gómez AM, Zhou YY, Ziman B, Spurgeon H, Lakatta EG, Lederer WJ. Excitation-contraction coupling in heart: new insights from Ca2+ sparks. Cell Calcium. 20: 129-40. PMID 8889204 DOI: 10.1016/S0143-4160(96)90102-5  0.609
1996 duBell WH, Lederer WJ, Rogers TB. Dynamic modulation of excitation-contraction coupling by protein phosphatases in rat ventricular myocytes. The Journal of Physiology. 493: 793-800. PMID 8799900 DOI: 10.1113/Jphysiol.1996.Sp021423  0.592
1996 Cheng H, Lederer MR, Lederer WJ, Cannell MB. Calcium sparks and [Ca2+]i waves in cardiac myocytes. The American Journal of Physiology. 270: C148-59. PMID 8772440 DOI: 10.1152/Ajpcell.1996.270.1.C148  0.578
1996 Lederer WJ, He S, Luo S, duBell W, Kofuji P, Kieval R, Neubauer CF, Ruknudin A, Cheng H, Cannell MB, Rogers TB, Schulze DH. The molecular biology of the Na(+)-Ca2+ exchanger and its functional roles in heart, smooth muscle cells, neurons, glia, lymphocytes, and nonexcitable cells. Annals of the New York Academy of Sciences. 779: 7-17. PMID 8659882 DOI: 10.1111/J.1749-6632.1996.Tb44764.X  0.522
1996 Schulze DH, Kofuji P, Valdivia C, He S, Luo S, Ruknudin A, Wisel S, Kirby MS, duBell W, Lederer WJ. Alternative splicing of the Na(+)-Ca2+ exchanger gene, NCX1. Annals of the New York Academy of Sciences. 779: 46-57. PMID 8659862 DOI: 10.1111/J.1749-6632.1996.Tb44769.X  0.479
1996 Doering AE, Eisner DA, Lederer WJ. Cardiac Na-Ca exchange and pH. Annals of the New York Academy of Sciences. 779: 182-98. PMID 8659826 DOI: 10.1111/J.1749-6632.1996.Tb44786.X  0.542
1996 Kohout TA, O'Brian JJ, Gaa ST, Lederer WJ, Rogers TB. Novel adenovirus component system that transfects cultured cardiac cells with high efficiency. Circulation Research. 78: 971-7. PMID 8635247  0.409
1996 Santana LF, Cheng H, Gómez AM, Cannell MB, Lederer WJ. Relation between the sarcolemmal Ca2+ current and Ca2+ sparks and local control theories for cardiac excitation-contraction coupling. Circulation Research. 78: 166-71. PMID 8603501 DOI: 10.1161/01.Res.78.1.166  0.596
1996 Klein MG, Cheng H, Santana LF, Jiang YH, Lederer WJ, Schneider MF. Two mechanisms of quantized calcium release in skeletal muscle. Nature. 379: 455-8. PMID 8559251 DOI: 10.1038/379455A0  0.544
1996 Li Z, Cheng H, Lederer WJ, Froehlich J, Lakalla EG. Enhanced proliferation and migration and altered cytoskeletal proteins in aortic early passage smooth muscle cells from old rats Faseb Journal. 10: A1016.  0.381
1996 Gómez AM, Cheng H, Lederer WJ, Bers DM. Ca2+ diffusion and sarcoplasmic reticulum transport both contribute to [Ca2+](i) decline during Ca2+ sparks in rat ventricular myocytes Journal of Physiology. 496: 575-581.  0.567
1995 Rogers TB, Inesi G, Wade R, Lederer WJ. Use of thapsigargin to study Ca2+ homeostasis in cardiac cells. Bioscience Reports. 15: 341-9. PMID 8825036 DOI: 10.1007/Bf01788366  0.633
1995 Lokuta AJ, Rogers TB, Lederer WJ, Valdivia HH. Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism. The Journal of Physiology. 487: 609-22. PMID 8544125 DOI: 10.1113/Jphysiol.1995.Sp020904  0.576
1995 Cheng H, Cannell MB, Lederer WJ. Partial inhibition of Ca2+ current by methoxyverapamil (D600) reveals spatial nonuniformities in [Ca2+]i during excitation-contraction coupling in cardiac myocytes. Circulation Research. 76: 236-41. PMID 7834834 DOI: 10.1161/01.Res.76.2.236  0.595
1995 Cannell MB, Cheng H, Lederer WJ. The control of calcium release in heart muscle. Science (New York, N.Y.). 268: 1045-9. PMID 7754384  0.488
1995 Cheng H, Fill M, Valdivia H, Lederer WJ. Models of Ca2+ release channel adaptation. Science (New York, N.Y.). 267: 2009-10. PMID 7701326 DOI: 10.1126/Science.7701326  0.533
1995 Valdivia HH, Kaplan JH, Ellis-Davies GC, Lederer WJ. Rapid adaptation of cardiac ryanodine receptors: modulation by Mg2+ and phosphorylation. Science (New York, N.Y.). 267: 1997-2000. PMID 7701323  0.599
1995 Nelson MT, Cheng H, Rubart M, Santana LF, Bonev AD, Knot HJ, Lederer WJ. Relaxation of arterial smooth muscle by calcium sparks. Science (New York, N.Y.). 270: 633-7. PMID 7570021 DOI: 10.1126/Science.270.5236.633  0.596
1995 Hadley RW, Lederer WJ. Nifedipine inhibits movement of cardiac calcium channels through late, but not early, gating transitions. The American Journal of Physiology. 269: H1784-90. PMID 7503278 DOI: 10.1152/Ajpheart.1995.269.5.H1784  0.546
1994 Piston DW, Kirby MS, Cheng H, Lederer WJ, Webb WW. Two-photon-excitation fluorescence imaging of three-dimensional calcium-ion activity. Applied Optics. 33: 662-9. PMID 20862061 DOI: 10.1364/Ao.33.000662  0.499
1994 Niggli E, Piston DW, Kirby MS, Cheng H, Sandison DR, Webb WW, Lederer WJ. A confocal laser scanning microscope designed for indicators with ultraviolet excitation wavelengths. The American Journal of Physiology. 266: C303-10. PMID 8304426 DOI: 10.1152/Ajpcell.1994.266.1.C303  0.446
1994 Lokuta A, Kirby MS, Gaa ST, Lederer WJ, Rogers TB. On establishing primary cultures of neonatal rat ventricular myocytes for analysis over long periods. Journal of Cardiovascular Electrophysiology. 5: 50-62. PMID 8186877 DOI: 10.1111/J.1540-8167.1994.Tb01114.X  0.431
1994 Lakowicz JR, Szmacinski H, Nowaczyk K, Lederer WJ, Kirby MS, Johnson ML. Fluorescence lifetime imaging of intracellular calcium in COS cells using Quin-2. Cell Calcium. 15: 7-27. PMID 8149407 DOI: 10.1016/0143-4160(94)90100-7  0.435
1994 Kofuji P, Lederer WJ, Schulze DH. Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger. The Journal of Biological Chemistry. 269: 5145-9. PMID 8106495  0.558
1994 Kirby MS, Hadley RW, Lederer WJ. Measurement of intracellular Ca2+ concentration using Indo-1 during simultaneous flash photolysis to release Ca2+ from DM-nitrophen. Pflã¼Gers Archiv : European Journal of Physiology. 427: 169-77. PMID 8058467 DOI: 10.1007/Bf00585957  0.576
1994 Xiao RP, Cheng H, Lederer WJ, Suzuki T, Lakatta EG. Dual regulation of Ca2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx. Proceedings of the National Academy of Sciences of the United States of America. 91: 9659-63. PMID 7937825 DOI: 10.1073/Pnas.91.20.9659  0.621
1994 Cannell MB, Cheng H, Lederer WJ. Spatial non-uniformities in [Ca2+]i during excitation-contraction coupling in cardiac myocytes. Biophysical Journal. 67: 1942-56. PMID 7858131 DOI: 10.1016/S0006-3495(94)80677-0  0.588
1994 Doering AE, Lederer WJ. The action of Na+ as a cofactor in the inhibition by cytoplasmic protons of the cardiac Na(+)-Ca2+ exchanger in the guinea-pig. The Journal of Physiology. 480: 9-20. PMID 7853229  0.551
1994 Cheng H, Cannell MB, Lederer WJ. Propagation of excitation-contraction coupling into ventricular myocytes. Pflã¼Gers Archiv : European Journal of Physiology. 428: 415-7. PMID 7816564 DOI: 10.1007/Bf00724526  0.622
1993 Szmacinski H, Lakowicz JR, Lederer WJ, Nowaczyk K, Johnson ML. Fluorescence lifetime imaging of intracellular calcium. Journal of Fluorescence. 3: 161-7. PMID 24234827 DOI: 10.1007/Bf00862736  0.409
1993 McDaniel LD, Lederer WJ, Kofuji P, Schulze DH, Kieval R, Schultz RA. Mapping of the human cardiac Na+/Ca2+ exchanger gene (NCX1) by fluorescent in situ hybridization to chromosome region 2p22-->p23. Cytogenetics and Cell Genetics. 63: 192-3. PMID 8485996 DOI: 10.1159/000133532  0.467
1993 Doering AE, Lederer WJ. The mechanism by which cytoplasmic protons inhibit the sodium-calcium exchanger in guinea-pig heart cells. The Journal of Physiology. 466: 481-99. PMID 8410703  0.59
1993 Hadley RW, Kirby MS, Lederer WJ, Kao JP. Does the use of DM-nitrophen, nitr-5, or diazo-2 interfere with the measurement of indo-1 fluorescence? Biophysical Journal. 65: 2537-46. PMID 8312490 DOI: 10.1016/S0006-3495(93)81328-6  0.454
1993 Ripoll C, Lederer WJ, Nichols CG. On the mechanism of inhibition of KATP channels by glibenclamide in rat ventricular myocytes. Journal of Cardiovascular Electrophysiology. 4: 38-47. PMID 8287235 DOI: 10.1111/J.1540-8167.1993.Tb01210.X  0.597
1993 Schulze D, Kofuji P, Hadley R, Kirby MS, Kieval RS, Doering A, Niggli E, Lederer WJ. Sodium/calcium exchanger in heart muscle: molecular biology, cellular function, and its special role in excitation-contraction coupling. Cardiovascular Research. 27: 1726-34. PMID 8275517 DOI: 10.1093/Cvr/27.10.1726  0.591
1993 Cohen NM, Lederer WJ. Calcium current in single human cardiac myocytes. Journal of Cardiovascular Electrophysiology. 4: 422-37. PMID 8269310  0.496
1993 Cheng H, Lederer WJ, Cannell MB. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science (New York, N.Y.). 262: 740-4. PMID 8235594 DOI: 10.1126/Science.8235594  0.492
1993 Niggli E, Lederer WJ. Activation of Na-Ca exchange current by photolysis of "caged calcium". Biophysical Journal. 65: 882-91. PMID 8218911 DOI: 10.1016/S0006-3495(93)81105-6  0.612
1993 Kofuji P, Lederer WJ, Schulze DH. Na/Ca exchanger isoforms expressed in kidney. The American Journal of Physiology. 265: F598-603. PMID 7694482 DOI: 10.1152/Ajprenal.1993.265.4.F598  0.493
1993 Ho K, Nichols CG, Lederer WJ, Lytton J, Vassilev PM, Kanazirska MV, Hebert SC. Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature. 362: 31-8. PMID 7680431 DOI: 10.1038/362031a0  0.591
1992 Kieval RS, Bloch RJ, Lindenmayer GE, Ambesi A, Lederer WJ. Immunofluorescence localization of the Na-Ca exchanger in heart cells. The American Journal of Physiology. 263: C545-50. PMID 1514597 DOI: 10.1152/Ajpcell.1992.263.2.C545  0.563
1992 Kofuji P, Hadley RW, Kieval RS, Lederer WJ, Schulze DH. Expression of the Na-Ca exchanger in diverse tissues: a study using the cloned human cardiac Na-Ca exchanger. The American Journal of Physiology. 263: C1241-9. PMID 1476165 DOI: 10.1152/Ajpcell.1992.263.6.C1241  0.585
1992 Hadley RW, Lederer WJ. Comparison of the effects of BAY K 8644 on cardiac Ca2+ current and Ca2+ channel gating current. The American Journal of Physiology. 262: H472-7. PMID 1371650 DOI: 10.1152/Ajpheart.1992.262.2.H472  0.531
1992 Valdivia HH, Kirby MS, Lederer WJ, Coronado R. Scorpion toxins targeted against the sarcoplasmic reticulum Ca(2+)-release channel of skeletal and cardiac muscle. Proceedings of the National Academy of Sciences of the United States of America. 89: 12185-9. PMID 1334561  0.591
1992 Kirby MS, Sagara Y, Gaa S, Inesi G, Lederer WJ, Rogers TB. Thapsigargin inhibits contraction and Ca2+ transient in cardiac cells by specific inhibition of the sarcoplasmic reticulum Ca2+ pump. The Journal of Biological Chemistry. 267: 12545-51. PMID 1320000  0.633
1992 Cohen NM, Lederer WJ, Nichols CG. Activation of ATP-sensitive potassium channels underlies contractile failure in single human cardiac myocytes during complete metabolic inhibition Journal of Cardiovascular Electrophysiology. 3: 56-63.  0.465
1991 Lederer WJ, Niggli E, Hadley RW. Response. Science (New York, N.Y.). 251: 1371. PMID 17816192 DOI: 10.1126/science.251.4999.1371  0.307
1991 Niggli E, Lederer WJ. Molecular operations of the sodium-calcium exchanger revealed by conformation currents. Nature. 349: 621-4. PMID 2000135 DOI: 10.1038/349621A0  0.598
1991 Nichols CG, Ripoll C, Lederer WJ. ATP-sensitive potassium channel modulation of the guinea pig ventricular action potential and contraction. Circulation Research. 68: 280-7. PMID 1984868 DOI: 10.1161/01.Res.68.1.280  0.622
1991 Niggli E, Lederer WJ. Restoring forces in cardiac myocytes. Insight from relaxations induced by photolysis of caged ATP. Biophysical Journal. 59: 1123-35. PMID 1868157 DOI: 10.1016/S0006-3495(91)82327-X  0.469
1991 Nichols CG, Lederer WJ. The mechanism of KATP channel inhibition by ATP. The Journal of General Physiology. 97: 1095-8. PMID 1865175 DOI: 10.1085/Jgp.97.5.1095  0.584
1991 Niggli E, Lederer WJ. Photorelease of Ca2+ produces Na-Ca exchange currents and Na-Ca exchange "gating" currents. Annals of the New York Academy of Sciences. 639: 61-70. PMID 1785890 DOI: 10.1111/J.1749-6632.1991.Tb17289.X  0.572
1991 Doering AE, Lederer WJ. Voltage-dependent block of the Na-Ca exchanger in heart muscle examined using giant excised patches from guinea pig cardiac myocytes. Annals of the New York Academy of Sciences. 639: 172-6. PMID 1785842  0.578
1991 Nichols CG, Lederer WJ, Cannell MB. ATP dependence of KATP channel kinetics in isolated membrane patches from rat ventricle. Biophysical Journal. 60: 1164-77. PMID 1760506 DOI: 10.1016/S0006-3495(91)82152-X  0.601
1991 Nichols CG, Lederer WJ. Adenosine triphosphate-sensitive potassium channels in the cardiovascular system. The American Journal of Physiology. 261: H1675-86. PMID 1750525 DOI: 10.1152/Ajpheart.1991.261.6.H1675  0.627
1991 Hadley RW, Lederer WJ. Ca2+ and voltage inactivate Ca2+ channels in guinea-pig ventricular myocytes through independent mechanisms. The Journal of Physiology. 444: 257-68. PMID 1668348 DOI: 10.1113/Jphysiol.1991.Sp018876  0.597
1991 Massey CV, Kohout TA, Gaa ST, Lederer WJ, Rogers TB. Molecular and cellular actions of platelet-activating factor in rat heart cells. The Journal of Clinical Investigation. 88: 2106-16. PMID 1661298 DOI: 10.1172/Jci115540  0.452
1991 Hadley RW, Lederer WJ. Properties of L-type calcium channel gating current in isolated guinea pig ventricular myocytes. The Journal of General Physiology. 98: 265-85. PMID 1658192 DOI: 10.1085/Jgp.98.2.265  0.543
1991 Abdellatif MM, Neubauer CF, Lederer WJ, Rogers TB. Angiotensin-induced desensitization of the phosphoinositide pathway in cardiac cells occurs at the level of the receptor. Circulation Research. 69: 800-9. PMID 1651818 DOI: 10.1161/01.Res.69.3.800  0.397
1990 Nichols CG, Lederer WJ. The regulation of ATP-sensitive K+ channel activity in intact and permeabilized rat ventricular myocytes. The Journal of Physiology. 423: 91-110. PMID 2388163 DOI: 10.1113/Jphysiol.1990.Sp018013  0.606
1990 Berlin JR, Wozniak MA, Cannell MB, Bloch RJ, Lederer WJ. Measurement of intracellular Ca2+ in BC3H-1 muscle cells with Fura-2: relationship to acetylcholine receptor synthesis. Cell Calcium. 11: 371-84. PMID 2364414 DOI: 10.1016/0143-4160(90)90040-2  0.566
1990 Lederer WJ, Berlin JR, Cohen NM, Hadley RW, Bers DM, Cannell MB. Excitation-contraction coupling in heart cells. Roles of the sodium-calcium exchange, the calcium current, and the sarcoplasmic reticulum. Annals of the New York Academy of Sciences. 588: 190-206. PMID 2357018 DOI: 10.1111/J.1749-6632.1990.Tb13210.X  0.482
1990 Niggli E, Lederer WJ. Real-time confocal microscopy and calcium measurements in heart muscle cells: towards the development of a fluorescence microscope with high temporal and spatial resolution. Cell Calcium. 11: 121-30. PMID 2354496 DOI: 10.1016/0143-4160(90)90065-3  0.459
1990 Bers DM, Lederer WJ, Berlin JR. Intracellular Ca transients in rat cardiac myocytes: role of Na-Ca exchange in excitation-contraction coupling. The American Journal of Physiology. 258: C944-54. PMID 2333986 DOI: 10.1152/Ajpcell.1990.258.5.C944  0.604
1990 Lederer WJ, Niggli E, Hadley RW. Sodium-calcium exchange in excitable cells: fuzzy space. Science (New York, N.Y.). 248: 283. PMID 2326638 DOI: 10.1126/Science.2326638  0.466
1990 Nichols CG, Niggli E, Lederer WJ. Modulation of ATP-sensitive potassium channel activity by flash-photolysis of 'caged-ATP' in rat heart cells. Pflã¼Gers Archiv : European Journal of Physiology. 415: 510-2. PMID 2315010 DOI: 10.1007/Bf00373635  0.61
1990 Nichols CG, Lederer WJ. The role of ATP in energy-deprivation contractures in unloaded rat ventricular myocytes. Canadian Journal of Physiology and Pharmacology. 68: 183-94. PMID 2311000 DOI: 10.1139/Y90-029  0.664
1990 Ripoll C, Lederer WJ, Nichols CG. Modulation of ATP-sensitive K+ channel activity and contractile behavior in mammalian ventricle by the potassium channel openers cromakalim and RP49356. The Journal of Pharmacology and Experimental Therapeutics. 255: 429-35. PMID 2243335  0.611
1990 Niggli E, Lederer WJ. Voltage-independent calcium release in heart muscle. Science (New York, N.Y.). 250: 565-8. PMID 2173135 DOI: 10.1126/Science.2173135  0.589
1989 Berlin JR, Cannell MB, Lederer WJ. Cellular origins of the transient inward current in cardiac myocytes. Role of fluctuations and waves of elevated intracellular calcium. Circulation Research. 65: 115-26. PMID 2736729  0.612
1989 Cannell MB, Berlin JR, Lederer WJ. Does voltage affect excitation-contraction coupling in the heart? Science (New York, N.Y.). 246: 1640. PMID 2627235  0.428
1989 Lederer WJ, Nichols CG. Nucleotide modulation of the activity of rat heart ATP-sensitive K+ channels in isolated membrane patches. The Journal of Physiology. 419: 193-211. PMID 2621629 DOI: 10.1113/Jphysiol.1989.Sp017869  0.606
1989 Lederer WJ, Nichols CG, Smith GL. The mechanism of early contractile failure of isolated rat ventricular myocytes subjected to complete metabolic inhibition. The Journal of Physiology. 413: 329-49. PMID 2600854 DOI: 10.1113/Jphysiol.1989.Sp017657  0.652
1989 Lederer WJ, Cannell MB, Cohen NM, Berlin JR. Excitation-contraction coupling in heart muscle. Molecular and Cellular Biochemistry. 89: 115-9. PMID 2554120  0.625
1989 Hadley RW, Lederer WJ. Intramembrane charge movement in guinea-pig and rat ventricular myocytes. The Journal of Physiology. 415: 601-24. PMID 2484211 DOI: 10.1113/Jphysiol.1989.Sp017738  0.39
1988 Stern MD, Silverman HS, Houser SR, Josephson RA, Capogrossi MC, Nichols CG, Lederer WJ, Lakatta EG. Anoxic contractile failure in rat heart myocytes is caused by failure of intracellular calcium release due to alteration of the action potential. Proceedings of the National Academy of Sciences of the United States of America. 85: 6954-8. PMID 3413129  0.615
1988 Cohen NM, Lederer WJ. Changes in the calcium current of rat heart ventricular myocytes during development. The Journal of Physiology. 406: 115-46. PMID 2855434  0.47
1988 Allen IS, Cohen NM, Dhallan RS, Gaa ST, Lederer WJ, Rogers TB. Angiotensin II increases spontaneous contractile frequency and stimulates calcium current in cultured neonatal rat heart myocytes: insights into the underlying biochemical mechanisms. Circulation Research. 62: 524-34. PMID 2449296 DOI: 10.1161/01.Res.62.3.524  0.447
1988 Döşemeci A, Dhallan RS, Cohen NM, Lederer WJ, Rogers TB. Phorbol ester increases calcium current and simulates the effects of angiotensin II on cultured neonatal rat heart myocytes. Circulation Research. 62: 347-57. PMID 2448059 DOI: 10.1161/01.Res.62.2.347  0.449
1987 Wier WG, Cannell MB, Berlin JR, Marban E, Lederer WJ. Cellular and subcellular heterogeneity of [Ca2+]i in single heart cells revealed by fura-2. Science (New York, N.Y.). 235: 325-8. PMID 3798114  0.683
1987 Vaughan-Jones RD, Eisner DA, Lederer WJ. Effects of changes of intracellular pH on contraction in sheep cardiac Purkinje fibers. The Journal of General Physiology. 89: 1015-32. PMID 3612086 DOI: 10.1085/Jgp.89.6.1015  0.418
1987 Cannell MB, Berlin JR, Lederer WJ. Intracellular calcium in cardiac myocytes: calcium transients measured using fluorescence imaging. Society of General Physiologists Series. 42: 201-14. PMID 3505361  0.607
1987 Berlin JR, Cannell MB, Lederer WJ. Regulation of twitch tension in sheep cardiac Purkinje fibers during calcium overload. The American Journal of Physiology. 253: H1540-7. PMID 3425753  0.48
1987 Cohen NM, Lederer WJ. Calcium current in isolated neonatal rat ventricular myocytes. The Journal of Physiology. 391: 169-91. PMID 2451004  0.472
1987 Cannell MB, Berlin JR, Lederer WJ. Effect of membrane potential changes on the calcium transient in single rat cardiac muscle cells. Science (New York, N.Y.). 238: 1419-23. PMID 2446391  0.495
1986 Cannell MB, Lederer WJ. The arrhythmogenic current ITI in the absence of electrogenic sodium-calcium exchange in sheep cardiac Purkinje fibres. The Journal of Physiology. 374: 201-19. PMID 3746687  0.454
1986 Cannell MB, Lederer WJ. A novel experimental chamber for single-cell voltage-clamp and patch-clamp applications with low electrical noise and excellent temperature and flow control. Pflã¼Gers Archiv : European Journal of Physiology. 406: 536-9. PMID 3714452  0.374
1986 Cannell MB, Eisner DA, Lederer WJ, Valdeolmillos M. Effects of membrane potential on intracellular calcium concentration in sheep Purkinje fibres in sodium-free solutions. The Journal of Physiology. 381: 193-203. PMID 3625534 DOI: 10.1113/Jphysiol.1986.Sp016322  0.579
1985 Cannell MB, Vaughan-Jones RD, Lederer WJ. Ryanodine block of calcium oscillations in heart muscle and the sodium-tension relationship. Federation Proceedings. 44: 2964-9. PMID 2998887  0.488
1985 Eisner DA, Lederer WJ. Na-Ca exchange: stoichiometry and electrogenicity. The American Journal of Physiology. 248: C189-202. PMID 2579566 DOI: 10.1152/Ajpcell.1985.248.3.C189  0.564
1985 Vaughan-Jones RD, Eisner DA, Lederer WJ. The effects of intracellular Na on contraction and intracellular pH in mammalian cardiac muscle. Advances in Myocardiology. 5: 313-30. PMID 2578682 DOI: 10.1007/978-1-4757-1287-2_24  0.584
1985 Sheu SS, Lederer WJ. Lidocaine's negative inotropic and antiarrhythmic actions. Dependence on shortening of action potential duration and reduction of intracellular sodium activity. Circulation Research. 57: 578-90. PMID 2412723 DOI: 10.1161/01.Res.57.4.578  0.486
1984 Lederer WJ, Sheu SS, Vaughan-Jones RD, Eisner DA. The effects of Na-Ca exchange on membrane currents in sheep cardiac Purkinje fibers. Society of General Physiologists Series. 38: 373-80. PMID 6695211  0.528
1984 Nelson MT, Lederer WJ. Sodium-dependent calcium efflux and sodium-dependent current in perfused barnacle muscle single cells. Society of General Physiologists Series. 38: 365-71. PMID 6695210  0.458
1984 Lederer WJ, Nelson MT. Sodium pump stoicheiometry determined by simultaneous measurements of sodium efflux and membrane current in barnacle. The Journal of Physiology. 348: 665-77. PMID 6325678 DOI: 10.1113/Jphysiol.1984.Sp015132  0.433
1984 Eisner DA, Lederer WJ, Vaughan-Jones RD. The electrogenic Na pump in mammalian cardiac muscle. Society of General Physiologists Series. 38: 193-213. PMID 6320458  0.446
1984 Eisner DA, Lederer WJ, Vaughan-Jones RD. The quantitative relationship between twitch tension and intracellular sodium activity in sheep cardiac Purkinje fibres. The Journal of Physiology. 355: 251-66. PMID 6092625 DOI: 10.1113/Jphysiol.1984.Sp015417  0.473
1983 Eisner DA, Lederer WJ, Vaughan-Jones RD. The control of tonic tension by membrane potential and intracellular sodium activity in the sheep cardiac Purkinje fibre. The Journal of Physiology. 335: 723-43. PMID 6875898 DOI: 10.1113/Jphysiol.1983.Sp014560  0.499
1983 Vaughan-Jones RD, Lederer WJ, Eisner DA. Ca2+ ions can affect intracellular pH in mammalian cardiac muscle. Nature. 301: 522-4. PMID 6823331 DOI: 10.1038/301522A0  0.593
1983 Eisner DA, Vaughan-Jones RD, Lederer WJ. Active transport and inotropic state in guinea pig left atrium. Circulation Research. 53: 834-6. PMID 6640867 DOI: 10.1161/01.Res.53.6.834  0.354
1983 Lederer WJ, Nelson MT. Effects of extracellular sodium on calcium efflux and membrane current in single muscle cells from the barnacle. The Journal of Physiology. 341: 325-39. PMID 6620183 DOI: 10.1113/Jphysiol.1983.Sp014808  0.591
1983 Lederer WJ. Piezoelectric translator. A simple and inexpensive device to move microelectrodes and micropipettes small distances rapidly. Pflã¼Gers Archiv : European Journal of Physiology. 399: 83-6. PMID 6359055 DOI: 10.1007/BF00652527  0.312
1983 Eisner DA, Lederer WJ, Sheu SS. The role of intracellular sodium activity in the anti-arrhythmic action of local anaesthetics in sheep Purkinje fibres. The Journal of Physiology. 340: 239-57. PMID 6310096 DOI: 10.1113/Jphysiol.1983.Sp014761  0.461
1982 Lederer WJ, Eisner DA. The effects of sodium pump activity on the slow inward current in sheep cardiac Purkinje fibres. Proceedings of the Royal Society of London. Series B, Biological Sciences. 214: 249-62. PMID 6127682 DOI: 10.1098/Rspb.1982.0008  0.437
1981 Eisner DA, Lederer WJ, Vaughan-Jones RD. The effects of rubidium ions and membrane potentials on the intracellular sodium activity of sheep Purkinje fibres. The Journal of Physiology. 317: 189-205. PMID 7310732 DOI: 10.1113/Jphysiol.1981.Sp013820  0.439
1981 Eisner DA, Lederer WJ, Vaughan-Jones RD. The dependence of sodium pumping and tension on intracellular sodium activity in voltage-clamped sheep Purkinje fibres. The Journal of Physiology. 317: 163-87. PMID 7310731 DOI: 10.1113/Jphysiol.1981.Sp013819  0.422
1980 Eisner DA, Lederer WJ. The relationship between sodium pump activity and twitch tension in cardiac Purkinje fibres. The Journal of Physiology. 303: 475-94. PMID 7431245 DOI: 10.1113/Jphysiol.1980.Sp013299  0.406
1980 Eisner DA, Lederer WJ. Characterization of the electrogenic sodium pump in cardiac Purkinje fibres. The Journal of Physiology. 303: 441-74. PMID 7431244 DOI: 10.1113/Jphysiol.1980.Sp013298  0.414
1979 Lederer WJ, Spindler AJ, Eisner DA. Thick slurry bevelling: a new technique for bevelling extremely fine microelectrodes and micropipettes. Pflã¼Gers Archiv : European Journal of Physiology. 381: 287-8. PMID 574638 DOI: 10.1007/Bf00583261  0.32
1979 Eisner DA, Lederer WJ. Does sodium pump inhibition produce the positive inotropic effects of strophanthidine in mammalian cardiac muscle? [proceedings]. The Journal of Physiology. 296: 75P-76P. PMID 529145  0.431
1979 Eisner DA, Lederer WJ. A cellular basis for lidocaine's anti-arrhythmic action [proceedings]. The Journal of Physiology. 295: 25P-26P. PMID 521930  0.343
1979 Eisner DA, Lederer WJ. The role of the sodium pump in the effects of potassium-depleted solutions on mammalian cardiac muscle. The Journal of Physiology. 294: 279-301. PMID 512947 DOI: 10.1113/Jphysiol.1979.Sp012930  0.409
1979 Eisner DA, Lederer WJ. Inotropic and arrhythmogenic effects of potassium-depleted solutions on mammalian cardiac muscle. The Journal of Physiology. 294: 255-77. PMID 512946 DOI: 10.1113/Jphysiol.1979.Sp012929  0.506
1979 Eisner DA, Lederer WJ, Noble D. Caffeine and tetracaine abolish the slow inward calcium current in sheep cardiac Purkinje fibres [proceedings]. The Journal of Physiology. 293: 76P-77P. PMID 501653  0.489
1978 DiFrancesco D, Eisner DA, Lederer WJ. Low-potassium inotropy in cardiac muscle [proceedings]. The Journal of Physiology. 284: 138P-139P. PMID 731484  0.424
1978 Kass RS, Lederer WJ, Tsien RW, Weingart R. Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres. The Journal of Physiology. 281: 187-208. PMID 702368 DOI: 10.1113/jphysiol.1978.sp012416  0.745
1978 Eisner DA, Lederer WJ, Ojeda C. Arrhythmogenic effects of hypokalaemia on mammalian ventricular muscle [proceedings]. The Journal of Physiology. 280: 74P-75P. PMID 690938  0.393
1976 Lederer WJ, Tsien RW. Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibres. The Journal of Physiology. 263: 73-100. PMID 1018270 DOI: 10.1113/jphysiol.1976.sp011622  0.582
1975 Lederer WJ, Tsien RW. Proceedings: Transient inward current underlying strophanthidin's enhancement of pace-maker activity in Purkinje fibres. The Journal of Physiology. 249: 40P-41P. PMID 1151871  0.553
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