Year |
Citation |
Score |
2011 |
Kim YH, Coon A, Baker AF, Powis G. Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase. Cancer Chemotherapy and Pharmacology. 68: 405-13. PMID 21069338 DOI: 10.1007/S00280-010-1500-0 |
0.509 |
|
2010 |
Snodgrass RG, Collier AC, Coon AE, Pritsos CA. Mitomycin C inhibits ribosomal RNA: a novel cytotoxic mechanism for bioreductive drugs. The Journal of Biological Chemistry. 285: 19068-75. PMID 20418373 DOI: 10.1074/Jbc.M109.040477 |
0.33 |
|
2007 |
Baker AF, Landowski T, Dorr R, Tate WR, Gard JM, Tavenner BE, Dragovich T, Coon A, Powis G. The antitumor agent imexon activates antioxidant gene expression: evidence for an oxidative stress response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3388-94. PMID 17545547 DOI: 10.1158/1078-0432.Ccr-06-0873 |
0.512 |
|
2004 |
Meuillet EJ, Ihle N, Baker AF, Gard JM, Stamper C, Williams R, Coon A, Mahadevan D, George BL, Kirkpatrick L, Powis G. In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX-316. Oncology Research. 14: 513-27. PMID 15559765 DOI: 10.3727/0965040042380487 |
0.544 |
|
2004 |
Meuillet EJ, Mahadevan D, Berggren M, Coon A, Powis G. Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. Archives of Biochemistry and Biophysics. 429: 123-33. PMID 15313215 DOI: 10.1016/J.Abb.2004.04.020 |
0.564 |
|
2003 |
Meuillet EJ, Mahadevan D, Vankayalapati H, Berggren M, Williams R, Coon A, Kozikowski AP, Powis G. Specific inhibition of the Akt1 pleckstrin homology domain by D-3-deoxy-phosphatidyl-myo-inositol analogues. Molecular Cancer Therapeutics. 2: 389-99. PMID 12700283 |
0.554 |
|
2000 |
Powis G, Mustacich D, Coon A. The role of the redox protein thioredoxin in cell growth and cancer. Free Radical Biology & Medicine. 29: 312-22. PMID 11035260 DOI: 10.1016/S0891-5849(00)00313-0 |
0.518 |
|
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