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Jörg Grandl - Publications

Affiliations: 
Duke University, Durham, NC 
Area:
Neurobiology
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31/50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Young MN, Sindoni MJ, Lewis AH, Zauscher S, Grandl J. The energetics of rapid cellular mechanotransduction. Proceedings of the National Academy of Sciences of the United States of America. 120: e2215747120. PMID 36795747 DOI: 10.1073/pnas.2215747120  0.456
2022 Young M, Lewis AH, Grandl J. Physics of mechanotransduction by Piezo ion channels. The Journal of General Physiology. 154. PMID 35593732 DOI: 10.1085/jgp.202113044  0.542
2021 Lewis AH, Grandl J. Piezo1 ion channels inherently function as independent mechanotransducers. Elife. 10. PMID 34711306 DOI: 10.7554/eLife.70988  0.487
2021 Lewis AH, Grandl J. Stretch and poke stimulation for characterizing mechanically activated ion channels. Methods in Enzymology. 654: 225-253. PMID 34120715 DOI: 10.1016/bs.mie.2020.12.024  0.557
2020 Lewis AH, Grandl J. An Internal Dial for Sensitivity and Gain of Rapid Mechanotransduction. Neuron. 106: 361-363. PMID 32380048 DOI: 10.1016/J.Neuron.2020.04.015  0.515
2020 Lewis AH, Grandl J. Inactivation Kinetics and Mechanical Gating of Piezo1 Ion Channels Depend on Subdomains within the Cap. Cell Reports. 30: 870-880.e2. PMID 31968259 DOI: 10.1016/J.Celrep.2019.12.040  0.586
2017 Wu J, Young M, Lewis AH, Martfeld AN, Kalmeta B, Grandl J. Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix. Cell Reports. 21: 2357-2366. PMID 29186675 DOI: 10.1016/J.Celrep.2017.10.120  0.606
2017 Hutson MR, Keyte AL, Hernández-Morales M, Gibbs E, Kupchinsky ZA, Argyridis I, Erwin KN, Pegram K, Kneifel M, Rosenberg PB, Matak P, Xie L, Grandl J, Davis EE, Katsanis N, et al. Temperature-activated ion channels in neural crest cells confer maternal fever-associated birth defects. Science Signaling. 10. PMID 29018170 DOI: 10.1126/Scisignal.Aal4055  0.536
2017 Lewis AH, Cui AF, McDonald MF, Grandl J. Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels. Cell Reports. 19: 2572-2585. PMID 28636944 DOI: 10.1016/J.Celrep.2017.05.079  0.506
2017 Dubin AE, Murthy S, Lewis AH, Brosse L, Cahalan SM, Grandl J, Coste B, Patapoutian A. Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization. Neuron. 94: 266-270.e3. PMID 28426961 DOI: 10.1016/J.Neuron.2017.03.039  0.728
2017 Dubin AE, Murthy S, Lewis AH, Brosse L, Cahalan SM, Grandl J, Coste B, Patapoutian A. Editorial Note to: Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization. Neuron. 94: 265. PMID 28426960 DOI: 10.1016/J.Neuron.2017.03.041  0.773
2017 Sosa-Pagán JO, Iversen ES, Grandl J. TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity. Scientific Reports. 7: 549. PMID 28373693 DOI: 10.1038/S41598-017-00636-4  0.618
2017 Grandl J. The Mechanism of Activation of Piezo Ion Channels Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.237  0.584
2016 Wu J, Lewis AH, Grandl J. Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels. Trends in Biochemical Sciences. PMID 27743844 DOI: 10.1016/J.Tibs.2016.09.004  0.626
2016 Wu J, Goyal R, Grandl J. Localized force application reveals mechanically sensitive domains of Piezo1. Nature Communications. 7: 12939. PMID 27694883 DOI: 10.1038/Ncomms12939  0.48
2015 Lewis AH, Grandl J. Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension. Elife. 4. PMID 26646186 DOI: 10.7554/Elife.12088  0.586
2015 Lewis AH, Grandl J. Author response: Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension Elife. DOI: 10.7554/Elife.12088.010  0.549
2014 Mauthner SE, Hwang RY, Lewis AH, Xiao Q, Tsubouchi A, Wang Y, Honjo K, Skene JH, Grandl J, Tracey WD. Balboa binds to pickpocket in vivo and is required for mechanical nociception in Drosophila larvae. Current Biology : Cb. 24: 2920-5. PMID 25454784 DOI: 10.1016/J.Cub.2014.10.038  0.546
2014 Lee W, Leddy HA, Chen Y, Lee SH, Zelenski NA, McNulty AL, Wu J, Beicker KN, Coles J, Zauscher S, Grandl J, Sachs F, Guilak F, Liedtke WB. Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proceedings of the National Academy of Sciences of the United States of America. 111: E5114-22. PMID 25385580 DOI: 10.1073/Pnas.1414298111  0.706
2014 Moldenhauer H, Latorre R, Grandl J. The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole. Plos One. 9: e106776. PMID 25181545 DOI: 10.1371/Journal.Pone.0106776  0.415
2014 Jabba S, Goyal R, Sosa-Pagán JO, Moldenhauer H, Wu J, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six. Neuron. 82: 1017-31. PMID 24814535 DOI: 10.1016/J.Neuron.2014.04.016  0.768
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/J.Bpj.2013.11.3537  0.737
2013 Kim SE, Patapoutian A, Grandl J. Single residues in the outer pore of TRPV1 and TRPV3 have temperature-dependent conformations. Plos One. 8: e59593. PMID 23555720 DOI: 10.1371/Journal.Pone.0059593  0.744
2012 Coste B, Xiao B, Santos JS, Syeda R, Grandl J, Spencer KS, Kim SE, Schmidt M, Mathur J, Dubin AE, Montal M, Patapoutian A. Piezo proteins are pore-forming subunits of mechanically activated channels. Nature. 483: 176-81. PMID 22343900 DOI: 10.1038/Nature10812  0.776
2010 Grandl J, Kim SE, Uzzell V, Bursulaya B, Petrus M, Bandell M, Patapoutian A. Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain. Nature Neuroscience. 13: 708-14. PMID 20414199 DOI: 10.1038/Nn.2552  0.769
2010 Patapoutian A, Grandl J. Probing Mechanisms of Temperature Sensitivity of Thermo-TRPs Biophysical Journal. 98: 421a. DOI: 10.1016/J.Bpj.2009.12.2277  0.727
2010 Grandl J, Kim SE, Uzzell V, Bursulaya B, Petrus M, Bandell M, Patapoutian A. Outer Pore Domain of TRPV1 Ion Channel is Required for Temperature-Independent Step During Temperature-Activation Biophysical Journal. 98: 227a. DOI: 10.1016/J.Bpj.2009.12.1227  0.744
2009 Hu H, Grandl J, Bandell M, Petrus M, Patapoutian A. Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4. Proceedings of the National Academy of Sciences of the United States of America. 106: 1626-31. PMID 19164517 DOI: 10.1073/Pnas.0812209106  0.758
2008 Grandl J, Hu H, Bandell M, Bursulaya B, Schmidt M, Petrus M, Patapoutian A. Pore region of TRPV3 ion channel is specifically required for heat activation. Nature Neuroscience. 11: 1007-13. PMID 19160498 DOI: 10.1038/Nn.2169  0.776
2007 Danelon C, Grandl J, Hovius R, Vogel H. Modulation of proton-induced current fluctuations in the human nicotinic acetylcholine receptor channel. Biochimica Et Biophysica Acta. 1768: 76-89. PMID 16956576 DOI: 10.1016/J.Bbamem.2006.07.015  0.494
2006 Grandl J, Danelon C, Hovius R, Vogel H. Functional asymmetry of transmembrane segments in nicotinic acetylcholine receptors. European Biophysics Journal : Ebj. 35: 685-93. PMID 16838147 DOI: 10.1007/S00249-006-0078-2  0.569
Low-probability matches (unlikely to be authored by this person)
2019 Chen LF, Lin YT, Gallegos DA, Hazlett MF, Gómez-Schiavon M, Yang MG, Kalmeta B, Zhou AS, Holtzman L, Gersbach CA, Grandl J, Buchler NE, West AE. Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes. Cell Reports. 26: 1174-1188.e5. PMID 30699347 DOI: 10.1016/J.Celrep.2019.01.032  0.268
2018 Lewis AH, Grandl J. A cellular mechanism for age-induced itch. Science (New York, N.Y.). 360: 492-493. PMID 29724942 DOI: 10.1126/Science.Aat5617  0.266
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2014 Jabba SV, Goyal R, Moldenhauer H, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures Biophysical Journal. 106: 639a. DOI: 10.1016/j.bpj.2013.11.3537  0.233
2007 Grandl J, Sakr E, Kotzyba-Hibert F, Krieger F, Bertrand S, Bertrand D, Vogel H, Goeldner M, Hovius R. Fluorescent epibatidine agonists for neuronal and muscle-type nicotinic acetylcholine receptors. Angewandte Chemie (International Ed. in English). 46: 3505-8. PMID 17385777 DOI: 10.1002/Anie.200604807  0.056
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