Nicolas Lindegger, PhD - Publications

Affiliations: 
Novartis, Basel, Basel-Stadt, France 

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Lindegger N, Sidharta PN, Reseski K, Dingemanse J. Macitentan, a dual endothelin receptor antagonist for the treatment of pulmonary arterial hypertension, does not affect cardiac repolarization in healthy subjects. Pulmonary Pharmacology & Therapeutics. 29: 41-8. PMID 24813561 DOI: 10.1016/j.pupt.2014.04.007  1
2014 Sidharta PN, Lindegger N, Ul? I, Dingemanse J. Pharmacokinetics of the novel dual endothelin receptor antagonist macitentan in subjects with hepatic or renal impairment. Journal of Clinical Pharmacology. 54: 291-300. PMID 24122797 DOI: 10.1002/jcph.193  1
2010 Shan J, Kushnir A, Betzenhauser MJ, Reiken S, Li J, Lehnart SE, Lindegger N, Mongillo M, Mohler PJ, Marks AR. Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice. The Journal of Clinical Investigation. 120: 4388-98. PMID 21099118 DOI: 10.1172/JCI32726  1
2009 Lindegger N, Hagen BM, Marks AR, Lederer WJ, Kass RS. Diastolic transient inward current in long QT syndrome type 3 is caused by Ca2+ overload and inhibited by ranolazine. Journal of Molecular and Cellular Cardiology. 47: 326-34. PMID 19371746 DOI: 10.1016/j.yjmcc.2009.04.003  1
2008 Lindegger N, Mongillo M. Look beyond the hERG mutation: a neutral SCN5A variant may turn lidocaine into a threat. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 5: 1575-6. PMID 18984535 DOI: 10.1016/j.hrthm.2008.09.006  1
2008 Kass RS, Lindegger N, Hagen B, Lederer WJ. Another calcium paradox in heart failure. Journal of Molecular and Cellular Cardiology. 45: 28-31. PMID 18504047 DOI: 10.1016/j.yjmcc.2008.04.001  1
2008 Lehnart SE, Mongillo M, Bellinger A, Lindegger N, Chen BX, Hsueh W, Reiken S, Wronska A, Drew LJ, Ward CW, Lederer WJ, Kass RS, Morley G, Marks AR. Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. The Journal of Clinical Investigation. 118: 2230-45. PMID 18483626 DOI: 10.1172/JCI35346  1
2008 Lindegger N, Kass RS. K+ channelopathies (I Ks and i Kr) Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention. 194-206. DOI: 10.1007/978-1-84628-854-8_12  1
2006 Fredj S, Lindegger N, Sampson KJ, Carmeliet P, Kass RS. Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes. Circulation Research. 99: 1225-32. PMID 17082480 DOI: 10.1161/01.RES.0000251305.25604.b0  1
2006 Momotake A, Lindegger N, Niggli E, Barsotti RJ, Ellis-Davies GC. The nitrodibenzofuran chromophore: a new caging group for ultra-efficient photolysis in living cells. Nature Methods. 3: 35-40. PMID 16369551 DOI: 10.1038/nmeth821  1
2005 Lindegger N, Niggli E. Paradoxical SR Ca2+ release in guinea-pig cardiac myocytes after beta-adrenergic stimulation revealed by two-photon photolysis of caged Ca2+. The Journal of Physiology. 565: 801-13. PMID 15774509 DOI: 10.1113/jphysiol.2005.084376  1
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