| Year |
Citation |
Score |
| 2022 |
Kong X, Xing E, Wu S, Zhuang T, Li PK, Li C, Cheng X. Computational modeling studies reveal the origin of the binding preference of 3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acids for AKR1C3 over its isoforms. Protein Science : a Publication of the Protein Society. e4499. PMID 36335585 DOI: 10.1002/pro.4499 |
0.327 |
|
| 2020 |
Gao AC, Armstrong CM, Liu C, Liu L, Yang JC, Lou W, Zhao R, Ning S, Lombard AP, Zhao J, D'Abronzo LS, Evans CP, Li PK. Steroid sulfatase stimulates intracrine androgen synthesis and is a therapeutic target for advanced prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32928794 DOI: 10.1158/1078-0432.Ccr-20-1682 |
0.361 |
|
| 2020 |
Liu C, Lou W, Yang JC, Ning S, Tepper C, Li P, Evans CP, Gao AC. Mp37-03 Modulating Hsp70/Stub1 Machinery By Novel Small Molecules Overcomes Enzalutamide Resistance In Lethal Prostate Cancer The Journal of Urology. 203. DOI: 10.1097/Ju.0000000000000886.03 |
0.33 |
|
| 2017 |
Tang Z, Acuña UM, Fernandes NF, Chettiar S, Li PK, DE Blanco EC. Structure-Activity Relationship of Niclosamide Derivatives. Anticancer Research. 37: 2839-2843. PMID 28551619 DOI: 10.21873/Anticanres.11635 |
0.384 |
|
| 2017 |
Sugimoto Y, Sawant DB, Fisk HA, Mao L, Li C, Chettiar S, Li PK, Darby MV, Brueggemeier RW. Novel pyrrolopyrimidines as Mps1/TTK kinase inhibitors for breast cancer. Bioorganic & Medicinal Chemistry. PMID 28259529 DOI: 10.1016/J.Bmc.2017.02.030 |
0.499 |
|
| 2016 |
Arend RC, Londoño-Joshi AI, Gangrade A, Katre AA, Kurpad C, Li Y, Samant RS, Li PK, Landen CN, Yang ES, Hidalgo B, Alvarez RD, Straughn JM, Forero A, Buchsbaum DJ. Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer. Oncotarget. PMID 27888804 DOI: 10.18632/Oncotarget.13466 |
0.406 |
|
| 2016 |
Lin L, Jou D, Wang Y, Ma H, Liu T, Fuchs J, Li PK, Lü J, Li C, Lin J. STAT3 as a potential therapeutic target in ALDH+ and CD44+/CD24+ stem cell-like pancreatic cancer cells. International Journal of Oncology. PMID 27748818 DOI: 10.3892/Ijo.2016.3728 |
0.346 |
|
| 2016 |
Zhao J, Yu H, Liu Y, Gibson SA, Yan Z, Xu X, Gaggar A, Li PK, Li C, Wei S, Benveniste EN, Qin H. Protective Effect of Suppressing STAT3 Activity in LPS-induced Acute Lung Injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00281.2016. PMID 27638904 DOI: 10.1152/Ajplung.00281.2016 |
0.301 |
|
| 2015 |
Walters Haygood CL, Arend RC, Gangrade A, Chettiar S, Regan N, Hassmann CJ, Li PK, Hidalgo B, Straughn JM, Buchsbaum DJ. Niclosamide Analogs for Treatment of Ovarian Cancer. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 25: 1377-85. PMID 26186072 DOI: 10.1097/Igc.0000000000000506 |
0.375 |
|
| 2015 |
Arend RC, Gangrade A, Haygood CLW, Kurpad C, Metge BJ, Samant RS, Li P, Li Y, Bhasin D, Landen C, Alvarez R, Straughn JM, Buchsbaum DJ. Abstract POSTER-THER-1402: Overcoming platinum resistance in ovarian cancer with niclosamide Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Ther-1402 |
0.417 |
|
| 2014 |
Kim TD, Fuchs JR, Schwartz E, Abdelhamid D, Etter J, Berry WL, Li C, Ihnat MA, Li PK, Janknecht R. Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors. American Journal of Translational Research. 6: 236-47. PMID 24936217 |
0.311 |
|
| 2014 |
Li Y, Li PK, Roberts MJ, Arend RC, Samant RS, Buchsbaum DJ. Multi-targeted therapy of cancer by niclosamide: A new application for an old drug. Cancer Letters. 349: 8-14. PMID 24732808 DOI: 10.1016/J.Canlet.2014.04.003 |
0.413 |
|
| 2014 |
Haygood CLW, Arend RC, Li P, Li Y, Kurpad C, Gangrade A, Straughn JM, Buchsbaum D. Abstract 4677: Niclosamide analogs for treatment of ovarian cancer Cancer Research. 74: 4677-4677. DOI: 10.1158/1538-7445.Am2014-4677 |
0.422 |
|
| 2014 |
Yang J, Keenan K, Mace T, Bekaii-Saab T, Fuchs J, Schwartz E, Li C, Lin J, Li P, Lesinski G. Abstract 4073: STAT3 inhibitors elicit direct anti-tumor effects against human biliary caner cell lines and limit release of immune suppressive cytokinesin vitro Cancer Research. 74: 4073-4073. DOI: 10.1158/1538-7445.Am2014-4073 |
0.419 |
|
| 2014 |
Arend RC, Haygood CLW, Kurpad C, Gangrade A, Li P, Li Y, Bhasin D, Straughn JM, Buchsbaum DJ. Abstract 2517: STAT3 inhibition by LLL12 in combination with niclosamide and chemotherapy in ovarian cancer Cancer Research. 74: 2517-2517. DOI: 10.1158/1538-7445.Am2014-2517 |
0.456 |
|
| 2013 |
Bhasin D, Etter JP, Chettiar SN, Mok M, Li PK. Antiproliferative activities and SAR studies of substituted anthraquinones and 1,4-naphthoquinones. Bioorganic & Medicinal Chemistry Letters. 23: 6864-7. PMID 24176397 DOI: 10.1016/J.Bmcl.2013.09.098 |
0.536 |
|
| 2013 |
Pandit B, Hu Z, Chettiar SN, Zink J, Xiao Z, Etter JP, Bhasin D, Li PK. Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action. Bioorganic & Medicinal Chemistry Letters. 23: 6902-4. PMID 24169233 DOI: 10.1016/J.Bmcl.2013.09.084 |
0.735 |
|
| 2013 |
Chettiar SN, Cooley JV, Park IH, Bhasin D, Chakravarti A, Li PK, Li C, Jacob NK. Design, synthesis and biological studies of survivin dimerization modulators that prolong mitotic cycle. Bioorganic & Medicinal Chemistry Letters. 23: 5429-33. PMID 23968825 DOI: 10.1016/J.Bmcl.2013.07.034 |
0.431 |
|
| 2013 |
Sattu K, Hochgräfe F, Wu J, Umapathy G, Schönherr C, Ruuth K, Chand D, Witek B, Fuchs J, Li PK, Hugosson F, Daly RJ, Palmer RH, Hallberg B. Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated ALK in neuroblastoma cells. The Febs Journal. 280: 5269-82. PMID 23889739 DOI: 10.1111/Febs.12453 |
0.377 |
|
| 2013 |
Kroon P, Berry PA, Stower MJ, Rodrigues G, Mann VM, Simms M, Bhasin D, Chettiar S, Li C, Li PK, Maitland NJ, Collins AT. JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells. Cancer Research. 73: 5288-98. PMID 23824741 DOI: 10.1158/0008-5472.Can-13-0874 |
0.383 |
|
| 2013 |
Bhasin D, Chettiar SN, Etter JP, Mok M, Li PK. Anticancer activity and SAR studies of substituted 1,4-naphthoquinones. Bioorganic & Medicinal Chemistry. 21: 4662-9. PMID 23791367 DOI: 10.1016/J.Bmc.2013.05.017 |
0.327 |
|
| 2013 |
Sun Y, Pandit B, Chettiar SN, Etter JP, Lewis A, Johnsamuel J, Li PK. Design, synthesis and biological studies of novel tubulin inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 4465-8. PMID 23790539 DOI: 10.1016/J.Bmcl.2013.04.078 |
0.792 |
|
| 2013 |
Wickham S, Regan N, West MB, Thai J, Cook PF, Terzyan SS, Li PK, Hanigan MH. Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors. The Biochemical Journal. 450: 547-57. PMID 23301618 DOI: 10.1042/Bj20121435 |
0.348 |
|
| 2012 |
Bill MA, Nicholas C, Mace TA, Etter JP, Li C, Schwartz EB, Fuchs JR, Young GS, Lin L, Lin J, He L, Phelps M, Li PK, Lesinski GB. Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines. Plos One. 7: e40724. PMID 22899991 DOI: 10.1371/Journal.Pone.0040724 |
0.365 |
|
| 2012 |
Sen M, Thomas SM, Kim S, Yeh JI, Ferris RL, Johnson JT, Duvvuri U, Lee J, Sahu N, Joyce S, Freilino ML, Shi H, Li C, Ly D, Rapireddy S, ... ... Li PK, et al. First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy. Cancer Discovery. 2: 694-705. PMID 22719020 DOI: 10.1158/2159-8290.Cd-12-0191 |
0.364 |
|
| 2012 |
Lin L, Benson DM, DeAngelis S, Bakan CE, Li PK, Li C, Lin J. A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells. International Journal of Cancer. Journal International Du Cancer. 130: 1459-69. PMID 21520044 DOI: 10.1002/Ijc.26152 |
0.386 |
|
| 2012 |
Onimoe GI, Liu A, Lin L, Wei CC, Schwartz EB, Bhasin D, Li C, Fuchs JR, Li PK, Houghton P, Termuhlen A, Gross T, Lin J. Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice. Investigational New Drugs. 30: 916-26. PMID 21340507 DOI: 10.1007/S10637-011-9645-1 |
0.41 |
|
| 2011 |
Agudelo-Garcia PA, De Jesus JK, Williams SP, Nowicki MO, Chiocca EA, Liyanarachchi S, Li PK, Lannutti JJ, Johnson JK, Lawler SE, Viapiano MS. Glioma cell migration on three-dimensional nanofiber scaffolds is regulated by substrate topography and abolished by inhibition of STAT3 signaling. Neoplasia (New York, N.Y.). 13: 831-40. PMID 21969816 DOI: 10.1593/Neo.11612 |
0.339 |
|
| 2011 |
Lin L, Liu A, Peng Z, Lin HJ, Li PK, Li C, Lin J. STAT3 is necessary for proliferation and survival in colon cancer-initiating cells. Cancer Research. 71: 7226-37. PMID 21900397 DOI: 10.1158/0008-5472.Can-10-4660 |
0.416 |
|
| 2011 |
Ball S, Li C, Li PK, Lin J. The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells. Plos One. 6: e18820. PMID 21526200 DOI: 10.1371/Journal.Pone.0018820 |
0.424 |
|
| 2011 |
Fossey SL, Bear MD, Lin J, Li C, Schwartz EB, Li PK, Fuchs JR, Fenger J, Kisseberth WC, London CA. The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. Bmc Cancer. 11: 112. PMID 21443800 DOI: 10.1186/1471-2407-11-112 |
0.472 |
|
| 2011 |
Wei CC, Ball S, Lin L, Liu A, Fuchs JR, Li PK, Li C, Lin J. Two small molecule compounds, LLL12 and FLLL32, exhibit potent inhibitory activity on STAT3 in human rhabdomyosarcoma cells. International Journal of Oncology. 38: 279-85. PMID 21109950 DOI: 10.3892/Ijo_00000848 |
0.45 |
|
| 2011 |
Yan F, Smith P, Alinari L, Ryu J, Yu B, Karkhanis V, Tae S, Patton JT, Wilding EE, Gordon K, Mahasenan K, Bhasin D, Agostinelli C, Pileri SA, Byrd JC, ... ... Li P, et al. Developing a Novel Class of Drug to Inhibit Protein Arginine Methyltransferase 5 (PRMT5) Enzyme Dysregulation in Mantle Cell Lymphoma Blood. 118: 595-595. DOI: 10.1182/Blood.V118.21.595.595 |
0.443 |
|
| 2011 |
Nicholas C, Yan F, Peters SB, Bill MA, Li P, Li C, Fuchs JR, Baiocchi R, Lesinski GB. Abstract 933: The expression of PRMT5 methyltransferase mediates cell survival and metastatic phenotype in malignant melanoma Cancer Research. 71: 933-933. DOI: 10.1158/1538-7445.Am2011-933 |
0.368 |
|
| 2011 |
Lin L, Li P, Fuchs J, Li C, Lin J. Abstract 2444: STAT3 is necessary for proliferation and survival in pancreatic cancer-initiating cells Cancer Research. 71: 2444-2444. DOI: 10.1158/1538-7445.Am2011-2444 |
0.394 |
|
| 2010 |
Mete E, Gul HI, Canturk P, Topcu Z, Pandit B, Gul M, Li PK. Biological activity of 1-aryl-3-phenethylamino-1-propanone hydrochlorides and 3-aroyl-4-aryl-1-phenethyl-4-piperidinols on PC-3 cells and DNA topoisomerase I enzyme. Zeitschrift FüR Naturforschung. C, Journal of Biosciences. 65: 647-52. PMID 21319705 DOI: 10.1515/Znc-2010-11-1203 |
0.772 |
|
| 2010 |
Lin L, Deangelis S, Foust E, Fuchs J, Li C, Li PK, Schwartz EB, Lesinski GB, Benson D, Lü J, Hoyt D, Lin J. A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells. Molecular Cancer. 9: 217. PMID 20712901 DOI: 10.1186/1476-4598-9-217 |
0.468 |
|
| 2010 |
Bill MA, Fuchs JR, Li C, Yui J, Bakan C, Benson DM, Schwartz EB, Abdelhamid D, Lin J, Hoyt DG, Fossey SL, Young GS, Carson WE, Li PK, Lesinski GB. The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Molecular Cancer. 9: 165. PMID 20576164 DOI: 10.1186/1476-4598-9-165 |
0.444 |
|
| 2010 |
Lin L, Hutzen B, Zuo M, Ball S, Deangelis S, Foust E, Pandit B, Ihnat MA, Shenoy SS, Kulp S, Li PK, Li C, Fuchs J, Lin J. Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells. Cancer Research. 70: 2445-54. PMID 20215512 DOI: 10.1158/0008-5472.Can-09-2468 |
0.765 |
|
| 2010 |
Lin L, Hutzen B, Li PK, Ball S, Zuo M, DeAngelis S, Foust E, Sobo M, Friedman L, Bhasin D, Cen L, Li C, Lin J. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells. Neoplasia (New York, N.Y.). 12: 39-50. PMID 20072652 DOI: 10.1593/Neo.91196 |
0.413 |
|
| 2010 |
Lin L, Li C, Li P, Fuchs J, Lin J. Abstract A100: STAT3 as a novel cancer prevention target in colorectal cancer stem cells Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-A100 |
0.422 |
|
| 2010 |
Zuo M, Lin L, Liu Y, DeAngelis S, Ball S, Li P, Li C, Lin J. Abstract B95: A novel small molecule, LLL12 inhibits STAT3 phosphorylation and activities and exhibits potent growth suppressive activity in human hepatocellular carcinoma cells Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-B95 |
0.374 |
|
| 2010 |
Abdelhamid D, Corcoran M, Etter JP, Hu S, Pandit B, Li C, Li P, Fuchs JR. Abstract 4502: Synthesis and evaluation of curcumin-like compounds as inhibitors of the JAK/STAT pathway in cancer Cancer Research. 70: 4502-4502. DOI: 10.1158/1538-7445.Am10-4502 |
0.799 |
|
| 2010 |
Lin L, Hutzen B, Peng Z, Lin H, Li P, Li C, Wicha M, Lin J. Abstract 4296: STAT3 is required for proliferation and tumor growth of breast cancer stem cells Cancer Research. 70: 4296-4296. DOI: 10.1158/1538-7445.Am10-4296 |
0.402 |
|
| 2010 |
Yalowich JC, Hornbaker M, Bodnar AJ, Jin S, Zhang Y, Day BW, Fuchs JR, Li P. Abstract 3498: The cytotoxicity and genotoxicity of etoposide and other phenolic and non-phenolic agents in human myeloid leukemia HL-60 cells: role of myeloperoxidase (MPO) Cancer Research. 70: 3498-3498. DOI: 10.1158/1538-7445.Am10-3498 |
0.381 |
|
| 2010 |
Liu Y, Li P, Li C, Lin J. Abstract 2275: A novel small molecule, LLL12, inhibits IL-6 induced STAT3 phosphorylation and nuclear translocation Cancer Research. 70: 2275-2275. DOI: 10.1158/1538-7445.Am10-2275 |
0.363 |
|
| 2010 |
Brueggemeier RW, Li P. Fundamentals of Steroid Chemistry and Biochemistry Burger's Medicinal Chemistry and Drug Discovery. 1-34. DOI: 10.1002/0471266949.Bmc053.Pub2 |
0.317 |
|
| 2009 |
Lin L, Hutzen B, Ball S, Foust E, Sobo M, Deangelis S, Pandit B, Friedman L, Li C, Li PK, Fuchs J, Lin J. New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells. Cancer Science. 100: 1719-27. PMID 19558577 DOI: 10.1111/J.1349-7006.2009.01220.X |
0.774 |
|
| 2009 |
Friedman L, Lin L, Ball S, Bekaii-Saab T, Fuchs J, Li PK, Li C, Lin J. Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells. Anti-Cancer Drugs. 20: 444-9. PMID 19384191 DOI: 10.1097/Cad.0B013E32832Afc04 |
0.397 |
|
| 2009 |
Fossey SL, Liao AT, McCleese JK, Bear MD, Lin J, Li PK, Kisseberth WC, London CA. Characterization of STAT3 activation and expression in canine and human osteosarcoma. Bmc Cancer. 9: 81. PMID 19284568 DOI: 10.1186/1471-2407-9-81 |
0.381 |
|
| 2009 |
Fuchs JR, Pandit B, Bhasin D, Etter JP, Regan N, Abdelhamid D, Li C, Lin J, Li PK. Structure-activity relationship studies of curcumin analogues. Bioorganic & Medicinal Chemistry Letters. 19: 2065-9. PMID 19249204 DOI: 10.1016/J.Bmcl.2009.01.104 |
0.787 |
|
| 2009 |
Lin L, Hutzen B, Peng Z, Lin H, Li P, Li C, Wicha M, Lin J. Abstract A54: STAT3 as a novel therapeutic target in human breast cancer stem cells Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A54 |
0.41 |
|
| 2008 |
Gul HI, Yerdelen KO, Das U, Gul M, Pandit B, Li PK, Dimmock JR. Synthesis and cytotoxicity of novel 3-aryl-1-(3'-dibenzylaminomethyl-4'-hydroxyphenyl)-propenones and related compounds. Chemical & Pharmaceutical Bulletin. 56: 1675-81. PMID 19043238 DOI: 10.1248/Cpb.56.1675 |
0.72 |
|
| 2008 |
Bhasin D, Cisek K, Pandharkar T, Regan N, Li C, Pandit B, Lin J, Li PK. Design, synthesis, and studies of small molecule STAT3 inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 391-5. PMID 18006313 DOI: 10.1016/J.Bmcl.2007.10.031 |
0.789 |
|
| 2007 |
Hackett J, Xiao Z, Zang XP, Lerner ML, Brackett DJ, Brueggemeier RW, Li PK, Pento JT. Development of keratinocyte growth factor receptor tyrosine kinase inhibitors for the treatment of cancer. Anticancer Research. 27: 3801-6. PMID 18225535 |
0.333 |
|
| 2007 |
de-Blanco EJ, Pandit B, Hu Z, Shi J, Lewis A, Li PK. Inhibitors of NF-kappaB derived from thalidomide. Bioorganic & Medicinal Chemistry Letters. 17: 6031-5. PMID 17845850 DOI: 10.1016/J.Bmcl.2007.01.088 |
0.761 |
|
| 2007 |
Selcer KW, Difrancesca HM, Chandra AB, Li PK. Immunohistochemical analysis of steroid sulfatase in human tissues. The Journal of Steroid Biochemistry and Molecular Biology. 105: 115-23. PMID 17604157 DOI: 10.1016/J.Jsbmb.2006.12.105 |
0.315 |
|
| 2007 |
Gul HI, Yerdelen KO, Gul M, Das U, Pandit B, Li PK, Secen H, Sahin F. Synthesis of 4'-hydroxy-3'-piperidinomethylchalcone derivatives and their cytotoxicity against PC-3 cell lines. Archiv Der Pharmazie. 340: 195-201. PMID 17351963 DOI: 10.1002/Ardp.200600072 |
0.755 |
|
| 2007 |
Ishida H, Nakata T, Suzuki M, Shiotsu Y, Tanaka H, Sato N, Terasaki Y, Takebayashi M, Anazawa H, Murakata C, Li PK, Kuwabara T, Akinaga S. A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models. Breast Cancer Research and Treatment. 106: 215-27. PMID 17268815 DOI: 10.1007/S10549-007-9495-X |
0.479 |
|
| 2007 |
Ishida H, Nakata T, Sato N, Li PK, Kuwabara T, Akinaga S. Inhibition of steroid sulfatase activity and cell proliferation in ZR-75-1 and BT-474 human breast cancer cells by KW-2581 in vitro and in vivo. Breast Cancer Research and Treatment. 104: 211-9. PMID 17061037 DOI: 10.1007/S10549-006-9404-8 |
0.473 |
|
| 2006 |
Gul HI, Das U, Pandit B, Li PK. Evaluation of the cytotoxicity of some mono-mannich bases and their corresponding azine derivatives against androgen-independent prostate cancer cells. Arzneimittel-Forschung. 56: 850-4. PMID 17260673 DOI: 10.1055/S-0031-1296797 |
0.732 |
|
| 2006 |
Pandit B, Sun Y, Chen P, Sackett DL, Hu Z, Rich W, Li C, Lewis A, Schaefer K, Li PK. Structure-activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416. Bioorganic & Medicinal Chemistry. 14: 6492-501. PMID 16860559 DOI: 10.1016/J.Bmc.2006.06.017 |
0.792 |
|
| 2006 |
Li PK, Pandit B, Sackett DL, Hu Z, Zink J, Zhi J, Freeman D, Robey RW, Werbovetz K, Lewis A, Li C. A thalidomide analogue with in vitro antiproliferative, antimitotic, and microtubule-stabilizing activities Molecular Cancer Therapeutics. 5: 450-456. PMID 16505120 DOI: 10.1158/1535-7163.Mct-05-0254 |
0.759 |
|
| 2005 |
Li PK, Xiao Z, Hu Z, Pandit B, Sun Y, Sackett DL, Werbovetz K, Lewis A, Johnsamuel J. Conformationally restricted analogs of Combretastatin A-4 derived from SU5416. Bioorganic & Medicinal Chemistry Letters. 15: 5382-5. PMID 16213720 DOI: 10.1016/J.Bmcl.2005.09.001 |
0.791 |
|
| 2005 |
Brueggemeier RW, Díaz-Cruz ES, Li PK, Sugimoto Y, Lin YC, Shapiro CL. Translational studies on aromatase, cyclooxygenases, and enzyme inhibitors in breast cancer. The Journal of Steroid Biochemistry and Molecular Biology. 95: 129-36. PMID 15964185 DOI: 10.1016/J.Jsbmb.2005.04.013 |
0.391 |
|
| 2003 |
Shi J, Xiao Z, Ihnat MA, Kamat C, Pandit B, Hu Z, Li PK. Structure-activity relationships studies of the anti-angiogenic activities of linomide. Bioorganic & Medicinal Chemistry Letters. 13: 1187-9. PMID 12643940 DOI: 10.1016/S0960-894X(03)00047-7 |
0.757 |
|
| 2002 |
Selcer KW, Kabler H, Sarap J, Xiao Z, Li PK. Inhibition of steryl sulfatase activity in LNCaP human prostate cancer cells. Steroids. 67: 821-6. PMID 12231117 DOI: 10.1016/S0039-128X(02)00030-2 |
0.485 |
|
| 2002 |
Marks MG, Shi J, Fry MO, Xiao Z, Trzyna M, Pokala V, Ihnat MA, Li PK. Effects of putative hydroxylated thalidomide metabolites on blood vessel density in the chorioallantoic membrane (CAM) assay and on tumor and endothelial cell proliferation. Biological & Pharmaceutical Bulletin. 25: 597-604. PMID 12033499 |
0.331 |
|
| 2001 |
Xiao Z, Waters NC, Woodard CL, Li Z, Li P. Design and synthesis of Pfmrk inhibitors as potential antimalarial agents. Bioorganic & Medicinal Chemistry Letters. 11: 2875-2878. PMID 11597420 DOI: 10.1016/S0960-894X(01)00578-9 |
0.489 |
|
| 2001 |
Bordt SL, McKeon RM, Li PK, Witt-Enderby PA, Melan MA. N1E-115 mouse neuroblastoma cells express MT1 melatonin receptors and produce neurites in response to melatonin. Biochimica Et Biophysica Acta. 1499: 257-64. PMID 11341973 DOI: 10.1016/S0167-4889(00)00127-0 |
0.328 |
|
| 2001 |
Chu G, Li P. SYNTHESIS OF NAPHTHALENIC MELATONIN RECEPTOR LIGANDS Synthetic Communications. 31: 621-629. DOI: 10.1081/Scc-100000591 |
0.335 |
|
| 2000 |
Clemens JW, Kabler HL, Sarap JL, Beyer AR, Li PK, Selcer KW. Steroid sulfatase activity in the rat ovary, cultured granulosa cells, and a granulosa cell line. The Journal of Steroid Biochemistry and Molecular Biology. 75: 245-52. PMID 11282278 DOI: 10.1016/S0960-0760(00)00171-0 |
0.375 |
|
| 1999 |
Kolli A, Chu GH, Rhodes ME, Inoue K, Selcer KW, Li PK. Development of (p-O-sulfamoyl)-N-alkanoyl-phenylalkyl amines as non-steroidal estrone sulfatase inhibitors. The Journal of Steroid Biochemistry and Molecular Biology. 68: 31-40. PMID 10215035 DOI: 10.1016/S0960-0760(98)00159-9 |
0.507 |
|
| 1999 |
Chu G, Peters A, Selcer KW, Li P. Synthesis and sulfatase inhibitory activities of (E)- and (Z)-4-hydroxytamoxifen sulfamates. Bioorganic & Medicinal Chemistry Letters. 9: 141-144. PMID 10021916 DOI: 10.1016/S0960-894X(98)00707-0 |
0.392 |
|
| 1998 |
Li PK, Chu GH, Guo JP, Peters A, Selcer KW. Development of potent non-estrogenic estrone sulfatase inhibitors. Steroids. 63: 425-32. PMID 9654650 DOI: 10.1016/S0039-128X(98)00044-0 |
0.486 |
|
| 1998 |
Chu G, Li P. Synthesis of a radiolabeled charged melatonin receptor ligand Journal of Labelled Compounds and Radiopharmaceuticals. 41: 435-441. DOI: 10.1002/(Sici)1099-1344(199805)41:5<435::Aid-Jlcr97>3.0.Co;2-L |
0.31 |
|
| 1997 |
Chu GH, Milano S, Kluth L, Rhodes M, Boni R, Johnson DA, Li PK. Structure-activity relationship studies of the amide functionality in (p-O-sulfamoyl)-N-alkanoyl tyramines as estrone sulfatase inhibitors. Steroids. 62: 530-5. PMID 9253792 DOI: 10.1016/S0039-128X(97)00038-X |
0.4 |
|
| 1996 |
Selcer KW, Jagannathan S, Rhodes ME, Li PK. Inhibition of placental estrone sulfatase activity and MCF-7 breast cancer cell proliferation by estrone-3-amino derivatives. The Journal of Steroid Biochemistry and Molecular Biology. 59: 83-91. PMID 9009241 DOI: 10.1016/S0960-0760(96)00089-1 |
0.542 |
|
| 1996 |
Li PK, Milano S, Kluth L, Rhodes ME. Synthesis and sulfatase inhibitory activities of non-steroidal estrone sulfatase inhibitors. The Journal of Steroid Biochemistry and Molecular Biology. 59: 41-8. PMID 9009236 DOI: 10.1016/S0960-0760(96)00093-3 |
0.484 |
|
| 1995 |
Li PK, Rhodes ME, Jagannathan S, Johnson DA. Reversal of scopolamine induced amnesia in rats by the steroid sulfatase inhibitor estrone-3-O-sulfamate. Brain Research. Cognitive Brain Research. 2: 251-4. PMID 8580738 DOI: 10.1016/0926-6410(95)90016-0 |
0.301 |
|
| 1995 |
Selcer KW, Li PK. Estrogenicity, antiestrogenicity and estrone sulfatase inhibition of estrone-3-amine and estrone-3-thiol. The Journal of Steroid Biochemistry and Molecular Biology. 52: 281-6. PMID 7696150 DOI: 10.1016/0960-0760(94)00176-M |
0.474 |
|
| 1994 |
Dibbelt L, Li PK, Pillai R, Knuppen R. Inhibition of human placental sterylsulfatase by synthetic analogs of estrone sulfate. The Journal of Steroid Biochemistry and Molecular Biology. 50: 261-6. PMID 7918111 DOI: 10.1016/0960-0760(94)90130-9 |
0.355 |
|
| 1993 |
Li PK, Pillai R, Young BL, Bender WH, Martino DM, Lin FT. Synthesis and biochemical studies of estrone sulfatase inhibitors. Steroids. 58: 106-11. PMID 8475513 DOI: 10.1016/0039-128X(93)90045-O |
0.435 |
|
| 1992 |
Brueggemeier RW, Katlic NE, Kenreigh CA, Li PK. Aromatase inhibition by 7-substituted steroids in human choriocarcinoma cell culture Journal of Steroid Biochemistry and Molecular Biology. 41: 85-90. PMID 1734938 DOI: 10.1016/0960-0760(92)90228-B |
0.464 |
|
| 1990 |
Brueggemeier RW, Li PK, Chen HH, Moh PP, Katlic NE. Biochemical and pharmacological development of steroidal inhibitors of aromatase Journal of Steroid Biochemistry and Molecular Biology. 37: 379-385. PMID 2257241 DOI: 10.1016/0960-0760(90)90488-7 |
0.454 |
|
| 1990 |
Li PK, Brueggemeier RW. 7-Substituted 1,4,6-androstatriene-3,17-diones as enzyme-activated irreversible inhibitors of aromatase Journal of Steroid Biochemistry. 36: 533-539. PMID 2214770 DOI: 10.1016/0022-4731(90)90170-W |
0.466 |
|
| 1990 |
Li PK, Brueggemeier RW. 7-substituted steroidal aromatase inhibitors: Structure-activity relationships and molecular modeling Journal of Enzyme Inhibition and Medicinal Chemistry. 4: 113-120. PMID 2098517 DOI: 10.3109/14756369009040732 |
0.41 |
|
| 1987 |
Li Pk, Chen HH, Katlic NE, Darby MV, Brueggemeier RW. 7α-substituted steroidal aromatase inhibitors in hormone-dependent breast cancer in culture and in vivo [Poster 23] Steroids. 50: 641-642. DOI: 10.1016/0039-128X(87)90064-X |
0.365 |
|
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