Paul Joseph Shaw - Publications

Washington University School of Medicine in St. Louis 
Sleep, Neuroscience, Drosophila

172 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Seugnet L, Dissel S, Thimgan M, Cao L, Shaw PJ. Identification of Genes that Maintain Behavioral and Structural Plasticity during Sleep Loss. Frontiers in Neural Circuits. 11: 79. PMID 29109678 DOI: 10.3389/Fncir.2017.00079  0.6
2016 Neenan ST, Piper R, White PR, Kemp P, Leighton TG, Shaw PJ. Does Masking Matter? Shipping Noise and Fish Vocalizations. Advances in Experimental Medicine and Biology. 875: 747-753. PMID 26611028 DOI: 10.1007/978-1-4939-2981-8_91  0.01
2016 Hardman CJ, Harrison DPG, Shaw PJ, Nevard TD, Hughes B, Potts SG, Norris K. Supporting local diversity of habitats and species on farmland: A comparison of three wildlife-friendly schemes Journal of Applied Ecology. 53: 171-180. DOI: 10.1111/1365-2664.12557  0.01
2015 Pancani S, Rowson J, Tindale W, Heron N, Langley J, McCarthy AD, Quinn A, Reed H, Stanton A, Shaw PJ, McDermott CJ, Mazzà C. Assessment of the Sheffield Support Snood, an innovative cervical orthosis designed for people affected by neck muscle weakness. Clinical Biomechanics (Bristol, Avon). PMID 26673978 DOI: 10.1016/j.clinbiomech.2015.11.010  0.04
2015 Kaufmann U, Shaw PJ, Kozhaya L, Subramanian R, Gaida K, Unutmaz D, McBride HJ, Feske S. Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 26673135 DOI: 10.4049/Jimmunol.1501406  0.08
2015 Shaw PJ, Kaewprommal P, Piriyapongsa J, Wongsombat C, Yuthavong Y, Kamchonwongpaisan S. Estimating mRNA lengths from Plasmodium falciparum genes by Virtual Northern RNA-seq analysis. International Journal For Parasitology. PMID 26548960 DOI: 10.1016/J.Ijpara.2015.09.007  0.01
2015 Wangkumhang P, Wilantho A, Shaw PJ, Flori L, Moazami-Goudarzi K, Gautier M, Duangjinda M, Assawamakin A, Tongsima S. Genetic analysis of Thai cattle reveals a Southeast Asian indicine ancestry. Peerj. 3: e1318. PMID 26528405 DOI: 10.7717/Peerj.1318  0.01
2015 Baker DJ, Blackburn DJ, Keatinge M, Sokhi D, Viskaitis P, Heath PR, Ferraiuolo L, Kirby J, Shaw PJ. Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis. Frontiers in Cellular Neuroscience. 9: 410. PMID 26528138 DOI: 10.3389/fncel.2015.00410  0.04
2015 Shaw PJ, Chaotheing S, Kaewprommal P, Piriyapongsa J, Wongsombat C, Suwannakitti N, Koonyosying P, Uthaipibull C, Yuthavong Y, Kamchonwongpaisan S. Plasmodium parasites mount an arrest response to dihydroartemisinin, as revealed by whole transcriptome shotgun sequencing (RNA-seq) and microarray study. Bmc Genomics. 16: 830. PMID 26490244 DOI: 10.1186/S12864-015-2040-0  0.01
2015 Rafiq MK, Shaw PJ. Cough assistance to clear lungs of ALS patients with severe bulbar dysfunction: Not a good idea! Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-2. PMID 26471227 DOI: 10.3109/21678421.2015.1099676  0.04
2015 Fluteau A, Ince PG, Minett T, Matthews FE, Brayne C, Garwood CJ, Ratcliffe LE, Morgan S, Heath PR, Shaw PJ, Wharton SB, Simpson JE. The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain. Neuroscience Letters. 609: 11-17. PMID 26455863 DOI: 10.1016/j.neulet.2015.10.001  0.04
2015 Wong CH, Topp S, Gkazi AS, Troakes C, Miller JW, de Majo M, Kirby J, Shaw PJ, Morrison KE, de Belleroche J, Vance CA, Al-Chalabi A, Al-Sarraj S, Shaw CE, Smith BN. The CHCHD10 P34S variant is not associated with ALS in a UK cohort of familial and sporadic patients. Neurobiology of Aging. 36: 2908.e17-8. PMID 26344877 DOI: 10.1016/j.neurobiolaging.2015.07.014  0.04
2015 Allen SP, Duffy LM, Shaw PJ, Grierson AJ. Altered age-related changes in bioenergetic properties and mitochondrial morphology in fibroblasts from sporadic amyotrophic lateral sclerosis patients. Neurobiology of Aging. 36: 2893-903. PMID 26344876 DOI: 10.1016/j.neurobiolaging.2015.07.013  0.04
2015 Bury JJ, Highley JR, Cooper-Knock J, Goodall EF, Higginbottom A, McDermott CJ, Ince PG, Shaw PJ, Kirby J. Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 26303227 DOI: 10.1111/neup.12240  0.04
2015 Rispo A, Williams ID, Shaw PJ. Source segregation and food waste prevention activities in high-density households in a deprived urban area. Waste Management (New York, N.Y.). 44: 15-27. PMID 26233881 DOI: 10.1016/j.wasman.2015.04.010  0.01
2015 Bogg TF, Shaw PJ, Cohn RJ, Wakefield CE, Hardy LL, Broderick C, Naumann F. Physical activity and screen-time of childhood haematopoietic stem cell transplant survivors. Acta Paediatrica (Oslo, Norway : 1992). 104: e455-9. PMID 26174593 DOI: 10.1111/apa.13120  0.01
2015 Smith L, Cupid BC, Dickie BG, Al-Chalabi A, Morrison KE, Shaw CE, Shaw PJ. Establishing the UK DNA Bank for motor neuron disease (MND). Bmc Genetics. 16: 84. PMID 26170009 DOI: 10.1186/s12863-015-0236-6  0.04
2015 Rafiq MK, Lee E, Bradburn M, McDermott CJ, Shaw PJ. Effect of lipid profile on prognosis in the patients with amyotrophic lateral sclerosis: Insights from the olesoxime clinical trial. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-7. PMID 26161993 DOI: 10.3109/21678421.2015.1062517  0.04
2015 Rafiq MK, Bradburn M, Proctor AR, Billings CG, Bianchi S, McDermott CJ, Shaw PJ. A preliminary randomized trial of the mechanical insufflator-exsufflator versus breath-stacking technique in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 26140500 DOI: 10.3109/21678421.2015.1051992  0.04
2015 Highley JR, Lorente Pons A, Cooper-Knock J, Wharton SB, Ince PG, Shaw PJ, Wood J, Kirby J. Motor neurone disease/amyotrophic lateral sclerosis associated with intermediate length CAG repeat expansions in Ataxin-2 does not have 1C2-positive polyglutamine inclusions. Neuropathology and Applied Neurobiology. PMID 26095883 DOI: 10.1111/nan.12254  0.04
2015 Simpson JE, Ince PG, Minett T, Matthews FE, Heath PR, Shaw PJ, Goodall E, Garwood CJ, Ratcliffe LE, Brayne C, Rattray M, Wharton SB. Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology. Neuropathology and Applied Neurobiology. PMID 26095650 DOI: 10.1111/nan.12252  0.04
2015 van der Kleij LA, Jones AR, Steen IN, Young CA, Shaw PJ, Shaw CE, Leigh PN, Turner MR, Al-Chalabi A. Regionality of disease progression predicts prognosis in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-6. PMID 26083873 DOI: 10.3109/21678421.2015.1051987  0.04
2015 Cooper-Knock J, Bury JJ, Heath PR, Wyles M, Higginbottom A, Gelsthorpe C, Highley JR, Hautbergue G, Rattray M, Kirby J, Shaw PJ. C9ORF72 GGGGCC Expanded Repeats Produce Splicing Dysregulation which Correlates with Disease Severity in Amyotrophic Lateral Sclerosis. Plos One. 10: e0127376. PMID 26016851 DOI: 10.1371/journal.pone.0127376  0.01
2015 Scarrott JM, Herranz-Martín S, Alrafiah AR, Shaw PJ, Azzouz M. Current developments in gene therapy for amyotrophic lateral sclerosis. Expert Opinion On Biological Therapy. 15: 935-47. PMID 25959569 DOI: 10.1517/14712598.2015.1044894  0.04
2015 Cooper-Knock J, Higginbottom A, Stopford MJ, Highley JR, Ince PG, Wharton SB, Pickering-Brown S, Kirby J, Hautbergue GM, Shaw PJ. Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy. Acta Neuropathologica. 130: 63-75. PMID 25943887 DOI: 10.1007/s00401-015-1429-9  0.04
2015 Lill CM, Rengmark A, Pihlstrøm L, Fogh I, Shatunov A, Sleiman PM, Wang LS, Liu T, Lassen CF, Meissner E, Alexopoulos P, Calvo A, Chio A, Dizdar N, Faltraco F, ... ... Shaw PJ, et al. The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25936935 DOI: 10.1016/J.Jalz.2014.12.009  0.04
2015 Dissel S, Angadi V, Kirszenblat L, Suzuki Y, Donlea J, Klose M, Koch Z, English D, Winsky-Sommerer R, van Swinderen B, Shaw PJ. Sleep restores behavioral plasticity to Drosophila mutants. Current Biology : Cb. 25: 1270-81. PMID 25913403 DOI: 10.1016/J.Cub.2015.03.027  1
2015 Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD. The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells. Immunity. 42: 654-64. PMID 25888258 DOI: 10.1016/J.Immuni.2015.03.006  0.08
2015 Thimgan MS, Toedebusch C, McLeland J, Duntley SP, Shaw PJ. Excessive daytime sleepiness is associated with changes in salivary inflammatory genes transcripts. Mediators of Inflammation. 2015: 539627. PMID 25873764 DOI: 10.1155/2015/539627  1
2015 Nicholls Z, Hobson E, Martindale J, Shaw PJ. Diagnosis of spinal xanthomatosis by next-generation sequencing: identifying a rare, treatable mimic of hereditary spastic paraparesis. Practical Neurology. 15: 280-3. PMID 25862734 DOI: 10.1136/practneurol-2015-001117  0.04
2015 Jones AR, Troakes C, King A, Sahni V, De Jong S, Bossers K, Papouli E, Mirza M, Al-Sarraj S, Shaw CE, Shaw PJ, Kirby J, Veldink JH, Macklis JD, Powell JF, et al. Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes. Neurobiology of Aging. 36: 2006.e1-9. PMID 25801576 DOI: 10.1016/J.Neurobiolaging.2015.02.017  0.04
2015 Farmer TD, Shaw PJ, Williams ID. Destined for indecision? A critical analysis of waste management practices in England from 1996 to 2013. Waste Management (New York, N.Y.). 39: 266-76. PMID 25771762 DOI: 10.1016/j.wasman.2015.02.023  0.01
2015 Cooper-Knock J, Kirby J, Highley R, Shaw PJ. The Spectrum of C9orf72-mediated Neurodegeneration and Amyotrophic Lateral Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 326-39. PMID 25731823 DOI: 10.1007/s13311-015-0342-1  0.04
2015 Mathur R, Ince PG, Minett T, Garwood CJ, Shaw PJ, Matthews FE, Brayne C, Simpson JE, Wharton SB. A reduced astrocyte response to β-amyloid plaques in the ageing brain associates with cognitive impairment. Plos One. 10: e0118463. PMID 25707004 DOI: 10.1371/journal.pone.0118463  0.04
2015 Faville R, Kottler B, Goodhill GJ, Shaw PJ, van Swinderen B. How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila. Scientific Reports. 5: 8454. PMID 25677943 DOI: 10.1038/Srep08454  1
2015 Lucey BP, Leahy A, Rosas R, Shaw PJ. A new model to study sleep deprivation-induced seizure. Sleep. 38: 777-85. PMID 25515102 DOI: 10.5665/Sleep.4674  1
2015 Dissel S, Seugnet L, Thimgan MS, Silverman N, Angadi V, Thacher PV, Burnham MM, Shaw PJ. Differential activation of immune factors in neurons and glia contribute to individual differences in resilience/vulnerability to sleep disruption. Brain, Behavior, and Immunity. 47: 75-85. PMID 25451614 DOI: 10.1016/J.Bbi.2014.09.019  1
2015 Simpson JE, Ince PG, Matthews FE, Shaw PJ, Heath PR, Brayne C, Garwood C, Higginbottom A, Wharton SB. A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort. Neuropathology and Applied Neurobiology. 41: 483-96. PMID 25443110 DOI: 10.1111/Nan.12202  0.04
2015 Beer AM, Cooper-Knock J, Higginbottom A, Highley JR, Wharton SB, Ince PG, Milano A, Jones AA, Al-Chalabi A, Kirby J, Shaw PJ. Intermediate length C9orf72 expansion in an ALS patient without classical C9orf72 neuropathology. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 16: 249-51. PMID 25436637 DOI: 10.3109/21678421.2014.977296  0.04
2015 Matthew TS, Laurent S, John T, Paul SJ. Identification of genes associated with resilience/vulnerability to sleep deprivation and starvation in Drosophila. Sleep. 38: 801-14. PMID 25409104 DOI: 10.5665/Sleep.4680  1
2015 Little D, Valori CF, Mutsaers CA, Bennett EJ, Wyles M, Sharrack B, Shaw PJ, Gillingwater TH, Azzouz M, Ning K. PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 270-7. PMID 25369768 DOI: 10.1038/mt.2014.209  0.01
2015 Walsh MJ, Cooper-Knock J, Dodd JE, Stopford MJ, Mihaylov SR, Kirby J, Shaw PJ, Hautbergue GM. Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art. Neuropathology and Applied Neurobiology. 41: 109-34. PMID 25319671 DOI: 10.1111/nan.12187  0.04
2015 Sutton R, Shaw PJ, Venn NC, Law T, Dissanayake A, Kilo T, Haber M, Norris MD, Fraser C, Alvaro F, Revesz T, Trahair TN, Dalla-Pozza L, Marshall GM, O'Brien TA. Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia. British Journal of Haematology. 168: 395-404. PMID 25312094 DOI: 10.1111/bjh.13142  0.01
2015 McGeachan AJ, Hobson EV, Shaw PJ, McDermott CJ. Developing an outcome measure for excessive saliva management in MND and an evaluation of saliva burden in Sheffield. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 16: 108-13. PMID 25225845 DOI: 10.3109/21678421.2014.951942  0.04
2015 Marino M, Papa S, Crippa V, Nardo G, Peviani M, Cheroni C, Trolese MC, Lauranzano E, Bonetto V, Poletti A, DeBiasi S, Ferraiuolo L, Shaw PJ, Bendotti C. Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis. Neurobiology of Aging. 36: 492-504. PMID 25085783 DOI: 10.1016/j.neurobiolaging.2014.06.026  0.04
2015 Raman R, Allen SP, Goodall EF, Kramer S, Ponger LL, Heath PR, Milo M, Hollinger HC, Walsh T, Highley JR, Olpin S, McDermott CJ, Shaw PJ, Kirby J. Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions. Neuropathology and Applied Neurobiology. 41: 201-26. PMID 24750211 DOI: 10.1111/nan.12147  0.04
2015 Balendra R, Jones A, Jivraj N, Steen IN, Young CA, Shaw PJ, Turner MR, Leigh PN, Al-Chalabi A. Use of clinical staging in amyotrophic lateral sclerosis for phase 3 clinical trials. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 45-9. PMID 24463480 DOI: 10.1136/Jnnp-2013-306865  0.04
2015 McDermott CJ, Shaw PJ, Cooper CL, Dixon S, Baird WO, Bradburn MJ, Fitzgerald P, Maguire C, Baxter SK, Williams T, Baudouin SV, Karat D, Talbot K, Stradling J, Maynard N, et al. Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): A multicentre, open-label, randomised controlled trial The Lancet Neurology. 14: 883-892. DOI: 10.1016/S1474-4422(15)00152-0  0.04
2015 Worthington TA, Shaw PJ, Daffern JR, Langford TEL. The effects of a thermal discharge on the macroinvertebrate community of a large British river: implications for climate change Hydrobiologia. 753: 81-95. DOI: 10.1007/s10750-015-2197-1  0.01
2014 Reed H, Langley J, Stanton A, Heron N, Clarke Z, Judge S, McCarthy A, Squire G, Quinn A, Wells O, Tindale W, Baxter S, Shaw PJ, McDermott CJ. Head-Up; An interdisciplinary, participatory and co-design process informing the development of a novel head and neck support for people living with progressive neck muscle weakness. Journal of Medical Engineering & Technology. 39: 404-10. PMID 26453038 DOI: 10.3109/03091902.2015.1088092  0.04
2014 Wongsombat C, Aroonsri A, Kamchonwongpaisan S, Morgan HP, Walkinshaw MD, Yuthavong Y, Shaw PJ. Molecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins. Molecular and Biochemical Parasitology. 198: 1-10. PMID 25447287 DOI: 10.1016/J.Molbiopara.2014.10.005  0.01
2014 Smith BN, Ticozzi N, Fallini C, Gkazi AS, Topp S, Kenna KP, Scotter EL, Kost J, Keagle P, Miller JW, Calini D, Vance C, Danielson EW, Troakes C, Tiloca C, ... ... Shaw PJ, et al. Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS. Neuron. 84: 324-31. PMID 25374358 DOI: 10.1016/J.Neuron.2014.09.027  0.04
2014 Bennett EJ, Mead RJ, Azzouz M, Shaw PJ, Grierson AJ. Early detection of motor dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis (ALS) using home cage running wheels. Plos One. 9: e107918. PMID 25268710 DOI: 10.1371/journal.pone.0107918  0.04
2014 Shaw PJ, Weidinger C, Vaeth M, Luethy K, Kaech SM, Feske S. CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2. The Journal of Clinical Investigation. 124: 4549-63. PMID 25157823 DOI: 10.1172/Jci76602  0.08
2014 Donlea JM, Ramanan N, Silverman N, Shaw PJ. Genetic rescue of functional senescence in synaptic and behavioral plasticity. Sleep. 37: 1427-37. PMID 25142573 DOI: 10.5665/Sleep.3988  1
2014 Elsworth B, Matthews K, Nie CQ, Kalanon M, Charnaud SC, Sanders PR, Chisholm SA, Counihan NA, Shaw PJ, Pino P, Chan JA, Azevedo MF, Rogerson SJ, Beeson JG, Crabb BS, et al. PTEX is an essential nexus for protein export in malaria parasites. Nature. 511: 587-91. PMID 25043043 DOI: 10.1038/nature13555  0.01
2014 Sleebs BE, Lopaticki S, Marapana DS, O'Neill MT, Rajasekaran P, Gazdik M, Günther S, Whitehead LW, Lowes KN, Barfod L, Hviid L, Shaw PJ, Hodder AN, Smith BJ, Cowman AF, et al. Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites. Plos Biology. 12: e1001897. PMID 24983235 DOI: 10.1371/journal.pbio.1001897  0.01
2014 Ramesh TM, Shaw PJ, McDearmid J. A zebrafish model exemplifies the long preclinical period of motor neuron disease. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 1288-9. PMID 24970908 DOI: 10.1136/jnnp-2014-308288  0.04
2014 Diekstra FP, Van Deerlin VM, van Swieten JC, Al-Chalabi A, Ludolph AC, Weishaupt JH, Hardiman O, Landers JE, Brown RH, van Es MA, Pasterkamp RJ, Koppers M, Andersen PM, Estrada K, Rivadeneira F, ... ... Shaw PJ, et al. C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. Annals of Neurology. 76: 120-33. PMID 24931836 DOI: 10.1002/Ana.24198  0.01
2014 Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J, Hautbergue GM, Shaw PJ. Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions. Brain : a Journal of Neurology. 137: 2040-51. PMID 24866055 DOI: 10.1093/brain/awu120  0.04
2014 Garwood CJ, Simpson JE, Al Mashhadi S, Axe C, Wilson S, Heath PR, Shaw PJ, Matthews FE, Brayne C, Ince PG, Wharton SB. DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort. Neuropathology and Applied Neurobiology. 40: 802-14. PMID 24861546 DOI: 10.1111/nan.12156  0.04
2014 Stavroulakis T, Baird WO, Baxter SK, Walsh T, Shaw PJ, McDermott CJ. The impact of gastrostomy in motor neurone disease: challenges and benefits from a patient and carer perspective. Bmj Supportive & Palliative Care. PMID 24848262 DOI: 10.1136/bmjspcare-2013-000609  0.04
2014 Highley JR, Kirby J, Jansweijer JA, Webb PS, Hewamadduma CA, Heath PR, Higginbottom A, Raman R, Ferraiuolo L, Cooper-Knock J, McDermott CJ, Wharton SB, Shaw PJ, Ince PG. Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones. Neuropathology and Applied Neurobiology. 40: 670-85. PMID 24750229 DOI: 10.1111/nan.12148  0.04
2014 Stavroulakis T, Baird WO, Baxter SK, Walsh T, Shaw PJ, McDermott CJ. Factors influencing decision-making in relation to timing of gastrostomy insertion in patients with motor neurone disease. Bmj Supportive & Palliative Care. 4: 57-63. PMID 24644772 DOI: 10.1136/bmjspcare-2013-000497  0.04
2014 Jones AR, Jivraj N, Balendra R, Murphy C, Kelly J, Thornhill M, Young C, Shaw PJ, Leigh PN, Turner MR, Steen IN, McCrone P, Al-Chalabi A. Health utility decreases with increasing clinical stage in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 285-91. PMID 24641613 DOI: 10.3109/21678421.2013.872149  0.04
2014 Savage AL, Wilm TP, Khursheed K, Shatunov A, Morrison KE, Shaw PJ, Shaw CE, Smith B, Breen G, Al-Chalabi A, Moss D, Bubb VJ, Quinn JP. An evaluation of a SVA retrotransposon in the FUS promoter as a transcriptional regulator and its association to ALS. Plos One. 9: e90833. PMID 24608899 DOI: 10.1371/Journal.Pone.0090833  0.04
2014 Cooper-Knock J, Shaw PJ, Kirby J. The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype. Acta Neuropathologica. 127: 333-45. PMID 24493408 DOI: 10.1007/s00401-014-1251-9  0.04
2014 Bayatti N, Cooper-Knock J, Bury JJ, Wyles M, Heath PR, Kirby J, Shaw PJ. Comparison of blood RNA extraction methods used for gene expression profiling in amyotrophic lateral sclerosis. Plos One. 9: e87508. PMID 24475299 DOI: 10.1371/journal.pone.0087508  0.04
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  0.04
2014 Allen SP, Rajan S, Duffy L, Mortiboys H, Higginbottom A, Grierson AJ, Shaw PJ. Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis. Neurobiology of Aging. 35: 1499-509. PMID 24439480 DOI: 10.1016/j.neurobiolaging.2013.11.025  0.04
2014 Meyer K, Ferraiuolo L, Miranda CJ, Likhite S, McElroy S, Renusch S, Ditsworth D, Lagier-Tourenne C, Smith RA, Ravits J, Burghes AH, Shaw PJ, Cleveland DW, Kolb SJ, Kaspar BK. Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS. Proceedings of the National Academy of Sciences of the United States of America. 111: 829-32. PMID 24379375 DOI: 10.1073/Pnas.1314085111  0.04
2014 Wood-Allum CA, Shaw PJ. Thyroid disease and the nervous system. Handbook of Clinical Neurology. 120: 703-35. PMID 24365348 DOI: 10.1016/B978-0-7020-4087-0.00048-6  0.04
2014 Fogh I, Ratti A, Gellera C, Lin K, Tiloca C, Moskvina V, Corrado L, Sorarù G, Cereda C, Corti S, Gentilini D, Calini D, Castellotti B, Mazzini L, Querin G, ... ... Shaw PJ, et al. A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 23: 2220-31. PMID 24256812 DOI: 10.1093/Hmg/Ddt587  0.04
2014 Da Costa MM, Allen CE, Higginbottom A, Ramesh T, Shaw PJ, McDermott CJ. A new zebrafish model produced by TILLING of SOD1-related amyotrophic lateral sclerosis replicates key features of the disease and represents a tool for in vivo therapeutic screening. Disease Models & Mechanisms. 7: 73-81. PMID 24092880 DOI: 10.1242/dmm.012013  0.04
2013 Heath PR, Kirby J, Shaw PJ. Investigating cell death mechanisms in amyotrophic lateral sclerosis using transcriptomics. Frontiers in Cellular Neuroscience. 7: 259. PMID 24381542 DOI: 10.3389/fncel.2013.00259  0.04
2013 Vanderheyden WM, Gerstner JR, Tanenhaus A, Yin JC, Shaw PJ. ERK phosphorylation regulates sleep and plasticity in Drosophila. Plos One. 8: e81554. PMID 24244744 DOI: 10.1371/Journal.Pone.0081554  1
2013 Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ, McDermott CJ. The impact on the family carer of motor neurone disease and intervention with noninvasive ventilation. Journal of Palliative Medicine. 16: 1602-9. PMID 24236958 DOI: 10.1089/jpm.2013.0211  0.04
2013 Christou YA, Ohyama K, Placzek M, Monk PN, Shaw PJ. Wild-type but not mutant SOD1 transgenic astrocytes promote the efficient generation of motor neuron progenitors from mouse embryonic stem cells. Bmc Neuroscience. 14: 126. PMID 24134124 DOI: 10.1186/1471-2202-14-126  0.04
2013 Goodall EF, Heath PR, Bandmann O, Kirby J, Shaw PJ. Neuronal dark matter: the emerging role of microRNAs in neurodegeneration. Frontiers in Cellular Neuroscience. 7: 178. PMID 24133413 DOI: 10.3389/fncel.2013.00178  0.04
2013 Cooper-Knock J, Higginbottom A, Connor-Robson N, Bayatti N, Bury JJ, Kirby J, Ninkina N, Buchman VL, Shaw PJ. C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles. Neurology. 81: 1719-21. PMID 24107864 DOI: 10.1212/01.wnl.0000435295.41974.2e  0.04
2013 Assawamakin A, Prueksaaroon S, Kulawonganunchai S, Shaw PJ, Varavithya V, Ruangrajitpakorn T, Tongsima S. Biomarker selection and classification of "-omics" data using a two-step bayes classification framework. Biomed Research International. 2013: 148014. PMID 24106694 DOI: 10.1155/2013/148014  0.01
2013 Nardo G, Iennaco R, Fusi N, Heath PR, Marino M, Trolese MC, Ferraiuolo L, Lawrence N, Shaw PJ, Bendotti C. Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 136: 3305-32. PMID 24065725 DOI: 10.1093/brain/awt250  0.04
2013 Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ, McDermott CJ. Use of non-invasive ventilation at end of life. Palliative Medicine. 27: 878. PMID 24058005 DOI: 10.1177/0269216313495098  0.04
2013 Prommana P, Uthaipibull C, Wongsombat C, Kamchonwongpaisan S, Yuthavong Y, Knuepfer E, Holder AA, Shaw PJ. Inducible knockdown of Plasmodium gene expression using the glmS ribozyme. Plos One. 8: e73783. PMID 24023691 DOI: 10.1371/Journal.Pone.0073783  0.01
2013 Gibbons CJ, Thornton EW, Ealing J, Shaw PJ, Talbot K, Tennant A, Young CA. Assessing social isolation in motor neurone disease: a Rasch analysis of the MND Social Withdrawal Scale. Journal of the Neurological Sciences. 334: 112-8. PMID 24011605 DOI: 10.1016/J.Jns.2013.08.002  0.04
2013 Waite JC, Vardhana S, Shaw PJ, Jang JE, McCarl CA, Cameron TO, Feske S, Dustin ML. Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo. European Journal of Immunology. 43: 3343-54. PMID 23939929 DOI: 10.1002/Eji.201243255  0.08
2013 Weidinger C, Shaw PJ, Feske S. STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells. Embo Molecular Medicine. 5: 1311-21. PMID 23922331 DOI: 10.1002/emmm.201302989  0.08
2013 Cooper-Knock J, Frolov A, Highley JR, Charlesworth G, Kirby J, Milano A, Hartley J, Ince PG, McDermott CJ, Lashley T, Revesz T, Shaw PJ, Wood NW, Bandmann O. C9ORF72 expansions, parkinsonism, and Parkinson disease: a clinicopathologic study. Neurology. 81: 808-11. PMID 23884045 DOI: 10.1212/WNL.0b013e3182a2cc38  0.04
2013 Richardson K, Allen SP, Mortiboys H, Grierson AJ, Wharton SB, Ince PG, Shaw PJ, Heath PR. The effect of SOD1 mutation on cellular bioenergetic profile and viability in response to oxidative stress and influence of mutation-type. Plos One. 8: e68256. PMID 23840839 DOI: 10.1371/journal.pone.0068256  0.04
2013 Jenkins TM, Burness C, Connolly DJ, Rao DG, Hoggard N, Mawson S, McDermott CJ, Wilkinson ID, Shaw PJ. A prospective pilot study measuring muscle volumetric change in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 414-23. PMID 23705876 DOI: 10.3109/21678421.2013.795597  0.04
2013 Groen EJ, Fumoto K, Blokhuis AM, Engelen-Lee J, Zhou Y, van den Heuvel DM, Koppers M, van Diggelen F, van Heest J, Demmers JA, Kirby J, Shaw PJ, Aronica E, Spliet WG, Veldink JH, et al. ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN. Human Molecular Genetics. 22: 3690-704. PMID 23681068 DOI: 10.1093/hmg/ddt222  0.01
2013 Turner MR, Bowser R, Bruijn L, Dupuis L, Ludolph A, McGrath M, Manfredi G, Maragakis N, Miller RG, Pullman SL, Rutkove SB, Shaw PJ, Shefner J, Fischbeck KH. Mechanisms, models and biomarkers in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 19-32. PMID 23678877 DOI: 10.3109/21678421.2013.778554  0.04
2013 Hobson EV, McGeachan A, Al-Chalabi A, Chandran S, Crawley F, Dick D, Donaghy C, Ealing J, Ellis CM, Gorrie G, Hanemann CO, Harrower T, Jung A, Majeed T, Malaspina A, ... ... Shaw PJ, et al. Management of sialorrhoea in motor neuron disease: a survey of current UK practice. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 521-7. PMID 23647474 DOI: 10.3109/21678421.2013.790452  0.04
2013 Thimgan MS, Gottschalk L, Toedebusch C, McLeland J, Rechtschaffen A, Gilliland-Roberts M, Duntley SP, Shaw PJ. Cross-translational studies in human and Drosophila identify markers of sleep loss. Plos One. 8: e61016. PMID 23637783 DOI: 10.1371/Journal.Pone.0061016  1
2013 Mok K, Laaksovirta H, Tienari PJ, Peuralinna T, Myllykangas L, Chiò A, Traynor BJ, Nalls MA, Gurunlian N, Shatunov A, Restagno G, Mora G, Nigel Leigh P, Shaw CE, Morrison KE, ... Shaw PJ, et al. Homozygosity analysis in amyotrophic lateral sclerosis. European Journal of Human Genetics : Ejhg. 21: 1429-35. PMID 23612577 DOI: 10.1038/Ejhg.2013.59  0.04
2013 Mead RJ, Higginbottom A, Allen SP, Kirby J, Bennett E, Barber SC, Heath PR, Coluccia A, Patel N, Gardner I, Brancale A, Grierson AJ, Shaw PJ. S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis. Free Radical Biology & Medicine. 61: 438-52. PMID 23608463 DOI: 10.1016/j.freeradbiomed.2013.04.018  0.04
2013 Sarkozy A, Hicks D, Hudson J, Laval SH, Barresi R, Hilton-Jones D, Deschauer M, Harris E, Rufibach L, Hwang E, Bashir R, Walter MC, Krause S, van den Bergh P, Illa I, ... ... Shaw PJ, et al. ANO5 gene analysis in a large cohort of patients with anoctaminopathy: confirmation of male prevalence and high occurrence of the common exon 5 gene mutation. Human Mutation. 34: 1111-8. PMID 23606453 DOI: 10.1002/Humu.22342  0.04
2013 Jones AR, Woollacott I, Shatunov A, Cooper-Knock J, Buchman V, Sproviero W, Smith B, Scott KM, Balendra R, Abel O, McGuffin P, Ellis CM, Shaw PJ, Morrison KE, Farmer A, et al. Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat. Neurobiology of Aging. 34: 2234.e1-7. PMID 23587638 DOI: 10.1016/J.Neurobiolaging.2013.03.003  0.04
2013 Buchman VL, Cooper-Knock J, Connor-Robson N, Higginbottom A, Kirby J, Razinskaya OD, Ninkina N, Shaw PJ. Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation. Molecular Neurodegeneration. 8: 12. PMID 23566336 DOI: 10.1186/1750-1326-8-12  0.04
2013 Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ, McDermott CJ. The use of non-invasive ventilation at end of life in patients with motor neurone disease: a qualitative exploration of family carer and health professional experiences. Palliative Medicine. 27: 516-23. PMID 23462702 DOI: 10.1177/0269216313478449  0.04
2013 Hewamadduma CA, Grierson AJ, Ma TP, Pan L, Moens CB, Ingham PW, Ramesh T, Shaw PJ. Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish. Human Molecular Genetics. 22: 2376-86. PMID 23427147 DOI: 10.1093/Hmg/Ddt082  0.04
2013 Turner MR, Hardiman O, Benatar M, Brooks BR, Chio A, de Carvalho M, Ince PG, Lin C, Miller RG, Mitsumoto H, Nicholson G, Ravits J, Shaw PJ, Swash M, Talbot K, et al. Controversies and priorities in amyotrophic lateral sclerosis. The Lancet. Neurology. 12: 310-22. PMID 23415570 DOI: 10.1016/S1474-4422(13)70036-X  0.04
2013 Shaw PJ, Qu B, Hoth M, Feske S. Molecular regulation of CRAC channels and their role in lymphocyte function. Cellular and Molecular Life Sciences : Cmls. 70: 2637-56. PMID 23052215 DOI: 10.1007/S00018-012-1175-2  0.08
2012 Piriyapongsa J, Ngamphiw C, Intarapanich A, Kulawonganunchai S, Assawamakin A, Bootchai C, Shaw PJ, Tongsima S. iLOCi: a SNP interaction prioritization technique for detecting epistasis in genome-wide association studies. Bmc Genomics. 13: S2. PMID 23281813 DOI: 10.1186/1471-2164-13-S7-S2  0.01
2012 Le Glou E, Seugnet L, Shaw PJ, Preat T, Goguel V. Circadian modulation of consolidated memory retrieval following sleep deprivation in Drosophila. Sleep. 35: 1377-1384B. PMID 23024436 DOI: 10.5665/Sleep.2118  1
2012 Ippagunta SK, Malireddi RK, Shaw PJ, Neale GA, Vande Walle L, Fukui Y, Green DR, Lamkanfi M, Kanneganti TD. Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines. Nature Immunology. 13: 701-2. PMID 22905357 DOI: 10.1038/Ni.2389  0.08
2012 Shaw PJ, Duntley SP. Neurological disorders: towards a mechanistic understanding of restless legs syndrome. Current Biology : Cb. 22: R485-6. PMID 22720681 DOI: 10.1016/J.Cub.2012.05.004  1
2012 Shaw PJ, Feske S. Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity. The Journal of Physiology. 590: 4157-67. PMID 22615435 DOI: 10.1113/Jphysiol.2012.233221  0.08
2012 Donlea J, Leahy A, Thimgan MS, Suzuki Y, Hughson BN, Sokolowski MB, Shaw PJ. Foraging alters resilience/vulnerability to sleep disruption and starvation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 109: 2613-8. PMID 22308351 DOI: 10.1073/Pnas.1112623109  1
2012 Shaw PJ, Feske S. Physiological and pathophysiological functions of SOCE in the immune system. Frontiers in Bioscience (Elite Edition). 4: 2253-68. PMID 22202035 DOI: 10.2741/540  0.08
2012 Donlea JM, Seugnet L, Shaw PJ. Genetics of sleep in drosophila melanogaster Drosophila Melanogaster: Life Cycle, Genetics and Development. 141-155.  1
2011 Gerstner JR, Vanderheyden WM, Shaw PJ, Landry CF, Yin JC. Cytoplasmic to nuclear localization of fatty-acid binding protein correlates with specific forms of long-term memory in Drosophila. Communicative & Integrative Biology. 4: 623-6. PMID 22046481 DOI: 10.4161/Cib.16927  0.84
2011 Thimgan MS, Duntley SP, Shaw PJ. Changes in gene expression with sleep. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 7: S26-7. PMID 22003326 DOI: 10.5664/Jcsm.1352  1
2011 Mullington JM, Czeisler CA, Goel N, Krueger JM, Balkin TJ, Johns M, Shaw PJ. Panel discussion: current status of measuring sleepiness. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 7: S22-5. PMID 22003325 DOI: 10.5664/Jcsm.1350  1
2011 Ippagunta SK, Malireddi RK, Shaw PJ, Neale GA, Vande Walle L, Green DR, Fukui Y, Lamkanfi M, Kanneganti TD. The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization. Nature Immunology. 12: 1010-6. PMID 21892172 DOI: 10.1038/Ni.2095  0.08
2011 Kritsiriwuthinan K, Chaotheing S, Shaw PJ, Wongsombat C, Chavalitshewinkoon-Petmitr P, Kamchonwongpaisan S. Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine. Malaria Journal. 10: 242. PMID 21849091 DOI: 10.1186/1475-2875-10-242  0.01
2011 Tongsima S, Assawamakin A, Piriyapongsa J, Shaw PJ. Comparative view of in silico DNA sequencing analysis tools. Methods in Molecular Biology (Clifton, N.J.). 760: 207-21. PMID 21779999 DOI: 10.1007/978-1-61779-176-5_13  0.01
2011 Maxwell SL, Culligan BK, Kelsey-Wall A, Shaw PJ. Rapid radiochemical method for determination of actinides in emergency concrete and brick samples. Analytica Chimica Acta. 701: 112-8. PMID 21763816 DOI: 10.1016/J.Aca.2011.06.011  0.01
2011 Ngamphiw C, Assawamakin A, Xu S, Shaw PJ, Yang JO, Ghang H, Bhak J, Liu E, Tongsima S. PanSNPdb: the Pan-Asian SNP genotyping database. Plos One. 6: e21451. PMID 21731755 DOI: 10.1371/Journal.Pone.0021451  0.01
2011 Donlea JM, Thimgan MS, Suzuki Y, Gottschalk L, Shaw PJ. Inducing sleep by remote control facilitates memory consolidation in Drosophila. Science (New York, N.Y.). 332: 1571-6. PMID 21700877 DOI: 10.1126/Science.1202249  1
2011 Limpiti T, Intarapanich A, Assawamakin A, Shaw PJ, Wangkumhang P, Piriyapongsa J, Ngamphiw C, Tongsima S. Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and structure. Bmc Bioinformatics. 12: 255. PMID 21699684 DOI: 10.1186/1471-2105-12-255  0.01
2011 van de Veerdonk FL, Joosten LA, Shaw PJ, Smeekens SP, Malireddi RK, van der Meer JW, Kullberg BJ, Netea MG, Kanneganti TD. The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis. European Journal of Immunology. 41: 2260-8. PMID 21681738 DOI: 10.1002/eji.201041226  0.08
2011 Seugnet L, Suzuki Y, Merlin G, Gottschalk L, Duntley SP, Shaw PJ. Notch signaling modulates sleep homeostasis and learning after sleep deprivation in Drosophila. Current Biology : Cb. 21: 835-40. PMID 21549599 DOI: 10.1016/J.Cub.2011.04.001  1
2011 Williams CD, Antoine DJ, Shaw PJ, Benson C, Farhood A, Williams DP, Kanneganti TD, Park BK, Jaeschke H. Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury. Toxicology and Applied Pharmacology. 252: 289-97. PMID 21396389 DOI: 10.1016/j.taap.2011.03.001  0.01
2011 Gerstner JR, Vanderheyden WM, Shaw PJ, Landry CF, Yin JC. Fatty-acid binding proteins modulate sleep and enhance long-term memory consolidation in Drosophila. Plos One. 6: e15890. PMID 21298037 DOI: 10.1371/Journal.Pone.0015890  1
2011 Seugnet L, Suzuki Y, Donlea JM, Gottschalk L, Shaw PJ. Sleep deprivation during early-adult development results in long-lasting learning deficits in adult Drosophila. Sleep. 34: 137-46. PMID 21286249 DOI: 10.1093/Sleep/34.2.137  1
2011 Shaw PJ, Barr MJ, Lukens JR, McGargill MA, Chi H, Mak TW, Kanneganti TD. Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity. Immunity. 34: 75-84. PMID 21236705 DOI: 10.1016/J.Immuni.2010.12.015  0.08
2011 Shaw PJ, McDermott MF, Kanneganti TD. Inflammasomes and autoimmunity. Trends in Molecular Medicine. 17: 57-64. PMID 21163704 DOI: 10.1016/j.molmed.2010.11.001  0.01
2011 Chanama M, Chanama S, Shaw PJ, Chitnumsub P, Leartsakulpanich U, Yuthavong Y. Formation of catalytically active cross-species heterodimers of thymidylate synthase from Plasmodium falciparum and Plasmodium vivax. Molecular Biology Reports. 38: 1029-37. PMID 20577818 DOI: 10.1007/S11033-010-0199-7  0.01
2010 Thimgan MS, Suzuki Y, Seugnet L, Gottschalk L, Shaw PJ. The perilipin homologue, lipid storage droplet 2, regulates sleep homeostasis and prevents learning impairments following sleep loss. Plos Biology. 8. PMID 20824166 DOI: 10.1371/Journal.Pbio.1000466  1
2010 Shaw PJ, Ganey PE, Roth RA. Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 7-18. PMID 20538741 DOI: 10.1093/Toxsci/Kfq168  0.08
2010 Shaw PJ, Lukens JR, Burns S, Chi H, McGargill MA, Kanneganti TD. Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 184: 4610-4. PMID 20368281 DOI: 10.4049/Jimmunol.1000217  0.08
2010 Shaw PJ, Lamkanfi M, Kanneganti TD. NOD-like receptor (NLR) signaling beyond the inflammasome. European Journal of Immunology. 40: 624-7. PMID 20201016 DOI: 10.1002/eji.200940211  0.01
2010 Bawankar P, Shaw PJ, Sardana R, Babar PH, Patankar S. 5' and 3' end modifications of spliceosomal RNAs in Plasmodium falciparum. Molecular Biology Reports. 37: 2125-33. PMID 19669595 DOI: 10.1007/s11033-009-9682-4  0.01
2010 Perlis M, Shaw PJ, Cano G, Espie CA. Models of Insomnia Principles and Practice of Sleep Medicine: Fifth Edition. 850-865. DOI: 10.1016/B978-1-4160-6645-3.00078-5  1
2010 Donlea JM, Shaw PJ. Mammalian Sleep and Circadian Rhythms: Flies Encyclopedia of Neuroscience. 649-655. DOI: 10.1016/B978-008045046-9.01614-4  1
2009 Donlea JM, Shaw PJ. Sleeping together using social interactions to understand the role of sleep in plasticity. Advances in Genetics. 68: 57-81. PMID 20109659 DOI: 10.1016/S0065-2660(09)68003-2  1
2009 Jongkon N, Mokmak W, Chuakheaw D, Shaw PJ, Tongsima S, Sangma C. Prediction of avian influenza A binding preference to human receptor using conformational analysis of receptor bound to hemagglutinin. Bmc Genomics. 10: S24. PMID 19958488 DOI: 10.1186/1471-2164-10-S3-S24  0.01
2009 Intarapanich A, Shaw PJ, Assawamakin A, Wangkumhang P, Ngamphiw C, Chaichoompu K, Piriyapongsa J, Tongsima S. Iterative pruning PCA improves resolution of highly structured populations. Bmc Bioinformatics. 10: 382. PMID 19930644 DOI: 10.1186/1471-2105-10-382  0.01
2009 Seugnet L, Galvin JE, Suzuki Y, Gottschalk L, Shaw PJ. Persistent short-term memory defects following sleep deprivation in a drosophila model of Parkinson disease. Sleep. 32: 984-92. PMID 19725249 DOI: 10.1093/Sleep/32.8.984  1
2009 Shaw PJ, Beggs KM, Sparkenbaugh EM, Dugan CM, Ganey PE, Roth RA. Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 111: 288-301. PMID 19638433 DOI: 10.1093/Toxsci/Kfp163  0.08
2009 Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proceedings of the National Academy of Sciences of the United States of America. 106: 12025-30. PMID 19587242 DOI: 10.1073/Pnas.0905922106  0.01
2009 Seugnet L, Suzuki Y, Thimgan M, Donlea J, Gimbel SI, Gottschalk L, Duntley SP, Shaw PJ. Identifying sleep regulatory genes using a Drosophila model of insomnia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7148-57. PMID 19494137 DOI: 10.1523/Jneurosci.5629-08.2009  1
2009 Shaw PJ, Fullerton AM, Scott MA, Ganey PE, Roth RA. The role of the hemostatic system in murine liver injury induced by coexposure to lipopolysaccharide and trovafloxacin, a drug with idiosyncratic liability. Toxicology and Applied Pharmacology. 236: 293-300. PMID 19367693 DOI: 10.1016/J.Taap.2009.01.018  0.08
2009 Shaw PJ, Ganey PE, Roth RA. Trovafloxacin enhances the inflammatory response to a Gram-negative or a Gram-positive bacterial stimulus, resulting in neutrophil-dependent liver injury in mice. The Journal of Pharmacology and Experimental Therapeutics. 330: 72-8. PMID 19351866 DOI: 10.1124/Jpet.109.151068  0.08
2009 Donlea JM, Ramanan N, Shaw PJ. Use-dependent plasticity in clock neurons regulates sleep need in Drosophila. Science (New York, N.Y.). 324: 105-8. PMID 19342592 DOI: 10.1126/Science.1166657  1
2009 Seugnet L, Suzuki Y, Stidd R, Shaw PJ. Aversive phototaxic suppression: evaluation of a short-term memory assay in Drosophila melanogaster. Genes, Brain, and Behavior. 8: 377-89. PMID 19220479 DOI: 10.1111/j.1601-183X.2009.00483.x  1
2009 Shaw PJ, Ditewig AC, Waring JF, Liguori MJ, Blomme EA, Ganey PE, Roth RA. Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury. Toxicological Sciences : An Official Journal of the Society of Toxicology. 107: 270-80. PMID 18930950 DOI: 10.1093/Toxsci/Kfn205  0.08
2009 Shaw PJ, Ganey PE, Roth RA. Tumor necrosis factor alpha is a proximal mediator of synergistic hepatotoxicity from trovafloxacin/lipopolysaccharide coexposure. The Journal of Pharmacology and Experimental Therapeutics. 328: 62-8. PMID 18820134 DOI: 10.1124/Jpet.108.143792  0.08
2008 Kilduff TS, Lein ES, de la Iglesia H, Sakurai T, Fu YH, Shaw P. New developments in sleep research: molecular genetics, gene expression, and systems neurobiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11814-8. PMID 19005045 DOI: 10.1523/Jneurosci.3768-08.2008  1
2008 Seugnet L, Suzuki Y, Vine L, Gottschalk L, Shaw PJ. D1 receptor activation in the mushroom bodies rescues sleep-loss-induced learning impairments in Drosophila. Current Biology : Cb. 18: 1110-7. PMID 18674913 DOI: 10.1016/J.Cub.2008.07.028  1
2008 Lemke S, Stauber M, Shaw PJ, Rafiqi AM, Prell A, Schmidt-Ott U. Bicoid occurrence and Bicoid-dependent hunchback regulation in lower cyclorrhaphan flies. Evolution & Development. 10: 413-20. PMID 18638318 DOI: 10.1111/J.1525-142X.2008.00252.X  0.01
2008 Shaw P, Ocorr K, Bodmer R, Oldham S. Drosophila aging 2006/2007. Experimental Gerontology. 43: 5-10. PMID 18061385 DOI: 10.1016/j.exger.2007.10.008  1
2007 Shaw PJ, Hopfensperger MJ, Ganey PE, Roth RA. Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 259-66. PMID 17709330 DOI: 10.1093/Toxsci/Kfm218  0.08
2007 Shaw PJ, Ponmee N, Karoonuthaisiri N, Kamchonwongpaisan S, Yuthavong Y. Characterization of human malaria parasite Plasmodium falciparum eIF4E homologue and mRNA 5' cap status. Molecular and Biochemical Parasitology. 155: 146-55. PMID 17692399 DOI: 10.1016/J.Molbiopara.2007.07.003  0.01
2006 Seugnet L, Boero J, Gottschalk L, Duntley SP, Shaw PJ. Identification of a biomarker for sleep drive in flies and humans. Proceedings of the National Academy of Sciences of the United States of America. 103: 19913-8. PMID 17167051 DOI: 10.1073/Pnas.0609463104  1
2006 Ganguly-Fitzgerald I, Donlea J, Shaw PJ. Waking experience affects sleep need in Drosophila. Science (New York, N.Y.). 313: 1775-81. PMID 16990546 DOI: 10.1126/Science.1130408  1
2006 Wratten NS, McGregor AP, Shaw PJ, Dover GA. Evolutionary and functional analysis of the tailless enhancer in Musca domestica and Drosophila melanogaster. Evolution & Development. 8: 6-15. PMID 16409378 DOI: 10.1111/j.1525-142X.2006.05070.x  0.01
2006 Dissel S, Shaw PJ. Drosophila model systems for genetic sleep research The Genetic Basis of Sleep and Sleep Disorders. 43-53. DOI: 10.1017/CBO9781139649469.007  1
2005 Luyendyk JP, Shaw PJ, Green CD, Maddox JF, Ganey PE, Roth RA. Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine. The Journal of Pharmacology and Experimental Therapeutics. 314: 1023-31. PMID 15933155 DOI: 10.1124/Jpet.105.087981  0.08
2005 Andretic R, Shaw PJ. Essentials of sleep recordings in Drosophila: moving beyond sleep time. Methods in Enzymology. 393: 759-72. PMID 15817323 DOI: 10.1016/S0076-6879(05)93040-1  1
2003 Shaw P. Awakening to the behavioral analysis of sleep in Drosophila Journal of Biological Rhythms. 18: 4-11. PMID 12568240 DOI: 10.1177/0748730402239672  1
2003 Shaw PJ, Franken P. Perchance to dream: solving the mystery of sleep through genetic analysis. Journal of Neurobiology. 54: 179-202. PMID 12486704 DOI: 10.1002/Neu.10167  1
2002 Shaw PJ, Tononi G, Greenspan RJ, Robinson DF. Stress response genes protect against lethal effects of sleep deprivation in Drosophila. Nature. 417: 287-91. PMID 12015603 DOI: 10.1038/417287A  1
2001 Greenspan RJ, Tononi G, Cirelli C, Shaw PJ. Sleep and the fruit fly. Trends in Neurosciences. 24: 142-5. PMID 11182453 DOI: 10.1016/S0166-2236(00)01719-7  1
2000 Shaw PJ, Cirelli C, Greenspan RJ, Tononi G. Correlates of sleep and waking in Drosophila melanogaster. Science (New York, N.Y.). 287: 1834-7. PMID 10710313 DOI: 10.1126/Science.287.5459.1834  1
1999 Cirelli C, Shaw PJ, Rechtschaffen A, Tononi G. No evidence of brain cell degeneration after long-term sleep deprivation in rats. Brain Research. 840: 184-93. PMID 10517970 DOI: 10.1016/S0006-8993(99)01768-0  1
1998 Shaw PJ, Bergmann BM, Rechtschaffen A. Effects of paradoxical sleep deprivation on thermoregulation in the rat. Sleep. 21: 7-17. PMID 9485528 DOI: 10.1093/Sleep/21.1.7  1
1997 Shaw PJ, Bergmann BM, Rechtschaffen A. Operant control of ambient temperature during sleep deprivation. The American Journal of Physiology. 272: R682-90. PMID 9124495 DOI: 10.1152/Ajpregu.1997.272.2.R682  1
1996 Bergmann BM, Gilliland MA, Feng PF, Russell DR, Shaw P, Wright M, Rechtschaffen A, Alverdy JC. Are physiological effects of sleep deprivation in the rat mediated by bacterial invasion? Sleep. 19: 554-62. PMID 8899934 DOI: 10.1093/Sleep/19.7.554  1
1995 Feng PF, Shaw P, Bergmann BM, Obermeyer W, Tsai LL, Zenko CE, Rechtschaffen A. Sleep deprivation in the rat: XX. Differences in wake and sleep temperatures during recovery. Sleep. 18: 797-804. PMID 8638074 DOI: 10.1093/Sleep/18.9.797  1
1981 Shaw PJ. A peak profile analysis procedure for extracting unit cell transform data from the Fourier transforms of periodic arrays Journal of Cell Science. 51: 314-321. PMID 7320087  1
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