Paul Joseph Shaw - Publications

Washington University School of Medicine in St. Louis 
Sleep, Neuroscience, Drosophila

47/360 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Seugnet L, Dissel S, Thimgan M, Cao L, Shaw PJ. Identification of Genes that Maintain Behavioral and Structural Plasticity during Sleep Loss. Frontiers in Neural Circuits. 11: 79. PMID 29109678 DOI: 10.3389/fncir.2017.00079  0.6
2015 Dissel S, Angadi V, Kirszenblat L, Suzuki Y, Donlea J, Klose M, Koch Z, English D, Winsky-Sommerer R, van Swinderen B, Shaw PJ. Sleep restores behavioral plasticity to Drosophila mutants. Current Biology : Cb. 25: 1270-81. PMID 25913403 DOI: 10.1016/j.cub.2015.03.027  1
2015 Thimgan MS, Toedebusch C, McLeland J, Duntley SP, Shaw PJ. Excessive daytime sleepiness is associated with changes in salivary inflammatory genes transcripts. Mediators of Inflammation. 2015: 539627. PMID 25873764 DOI: 10.1155/2015/539627  1
2015 Faville R, Kottler B, Goodhill GJ, Shaw PJ, van Swinderen B. How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila. Scientific Reports. 5: 8454. PMID 25677943 DOI: 10.1038/srep08454  1
2015 Lucey BP, Leahy A, Rosas R, Shaw PJ. A new model to study sleep deprivation-induced seizure. Sleep. 38: 777-85. PMID 25515102 DOI: 10.5665/sleep.4674  1
2015 Dissel S, Seugnet L, Thimgan MS, Silverman N, Angadi V, Thacher PV, Burnham MM, Shaw PJ. Differential activation of immune factors in neurons and glia contribute to individual differences in resilience/vulnerability to sleep disruption. Brain, Behavior, and Immunity. 47: 75-85. PMID 25451614 DOI: 10.1016/j.bbi.2014.09.019  1
2015 Matthew TS, Laurent S, John T, Paul SJ. Identification of genes associated with resilience/vulnerability to sleep deprivation and starvation in Drosophila. Sleep. 38: 801-14. PMID 25409104 DOI: 10.5665/sleep.4680  1
2014 Donlea JM, Ramanan N, Silverman N, Shaw PJ. Genetic rescue of functional senescence in synaptic and behavioral plasticity. Sleep. 37: 1427-37. PMID 25142573 DOI: 10.5665/sleep.3988  1
2013 Vanderheyden WM, Gerstner JR, Tanenhaus A, Yin JC, Shaw PJ. ERK phosphorylation regulates sleep and plasticity in Drosophila. Plos One. 8: e81554. PMID 24244744 DOI: 10.1371/journal.pone.0081554  1
2013 Thimgan MS, Gottschalk L, Toedebusch C, McLeland J, Rechtschaffen A, Gilliland-Roberts M, Duntley SP, Shaw PJ. Cross-translational studies in human and Drosophila identify markers of sleep loss. Plos One. 8: e61016. PMID 23637783 DOI: 10.1371/journal.pone.0061016  1
2012 Le Glou E, Seugnet L, Shaw PJ, Preat T, Goguel V. Circadian modulation of consolidated memory retrieval following sleep deprivation in Drosophila. Sleep. 35: 1377-1384B. PMID 23024436 DOI: 10.5665/sleep.2118  1
2012 Shaw PJ, Duntley SP. Neurological disorders: towards a mechanistic understanding of restless legs syndrome. Current Biology : Cb. 22: R485-6. PMID 22720681 DOI: 10.1016/j.cub.2012.05.004  1
2012 Donlea J, Leahy A, Thimgan MS, Suzuki Y, Hughson BN, Sokolowski MB, Shaw PJ. Foraging alters resilience/vulnerability to sleep disruption and starvation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 109: 2613-8. PMID 22308351 DOI: 10.1073/pnas.1112623109  1
2012 Donlea JM, Seugnet L, Shaw PJ. Genetics of sleep in drosophila melanogaster Drosophila Melanogaster: Life Cycle, Genetics and Development. 141-155.  1
2011 Gerstner JR, Vanderheyden WM, Shaw PJ, Landry CF, Yin JC. Cytoplasmic to nuclear localization of fatty-acid binding protein correlates with specific forms of long-term memory in Drosophila. Communicative & Integrative Biology. 4: 623-6. PMID 22046481 DOI: 10.4161/cib.4.5.16927  0.84
2011 Thimgan MS, Duntley SP, Shaw PJ. Changes in gene expression with sleep. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 7: S26-7. PMID 22003326 DOI: 10.5664/JCSM.1352  1
2011 Mullington JM, Czeisler CA, Goel N, Krueger JM, Balkin TJ, Johns M, Shaw PJ. Panel discussion: current status of measuring sleepiness. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 7: S22-5. PMID 22003325 DOI: 10.5664/JCSM.1350  1
2011 Donlea JM, Thimgan MS, Suzuki Y, Gottschalk L, Shaw PJ. Inducing sleep by remote control facilitates memory consolidation in Drosophila. Science (New York, N.Y.). 332: 1571-6. PMID 21700877 DOI: 10.1126/science.1202249  1
2011 Seugnet L, Suzuki Y, Merlin G, Gottschalk L, Duntley SP, Shaw PJ. Notch signaling modulates sleep homeostasis and learning after sleep deprivation in Drosophila. Current Biology : Cb. 21: 835-40. PMID 21549599 DOI: 10.1016/j.cub.2011.04.001  1
2011 Gerstner JR, Vanderheyden WM, Shaw PJ, Landry CF, Yin JC. Fatty-acid binding proteins modulate sleep and enhance long-term memory consolidation in Drosophila. Plos One. 6: e15890. PMID 21298037 DOI: 10.1371/journal.pone.0015890  1
2011 Seugnet L, Suzuki Y, Donlea JM, Gottschalk L, Shaw PJ. Sleep deprivation during early-adult development results in long-lasting learning deficits in adult Drosophila. Sleep. 34: 137-46. PMID 21286249  1
2010 Thimgan MS, Suzuki Y, Seugnet L, Gottschalk L, Shaw PJ. The perilipin homologue, lipid storage droplet 2, regulates sleep homeostasis and prevents learning impairments following sleep loss. Plos Biology. 8. PMID 20824166 DOI: 10.1371/journal.pbio.1000466  1
2010 Perlis M, Shaw PJ, Cano G, Espie CA. Models of Insomnia Principles and Practice of Sleep Medicine: Fifth Edition. 850-865. DOI: 10.1016/B978-1-4160-6645-3.00078-5  1
2010 Donlea JM, Shaw PJ. Mammalian Sleep and Circadian Rhythms: Flies Encyclopedia of Neuroscience. 649-655. DOI: 10.1016/B978-008045046-9.01614-4  1
2009 Donlea JM, Shaw PJ. Sleeping together using social interactions to understand the role of sleep in plasticity. Advances in Genetics. 68: 57-81. PMID 20109659 DOI: 10.1016/S0065-2660(09)68003-2  1
2009 Seugnet L, Galvin JE, Suzuki Y, Gottschalk L, Shaw PJ. Persistent short-term memory defects following sleep deprivation in a drosophila model of Parkinson disease. Sleep. 32: 984-92. PMID 19725249  1
2009 Seugnet L, Suzuki Y, Thimgan M, Donlea J, Gimbel SI, Gottschalk L, Duntley SP, Shaw PJ. Identifying sleep regulatory genes using a Drosophila model of insomnia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7148-57. PMID 19494137 DOI: 10.1523/JNEUROSCI.5629-08.2009  1
2009 Donlea JM, Ramanan N, Shaw PJ. Use-dependent plasticity in clock neurons regulates sleep need in Drosophila. Science (New York, N.Y.). 324: 105-8. PMID 19342592 DOI: 10.1126/science.1166657  1
2009 Seugnet L, Suzuki Y, Stidd R, Shaw PJ. Aversive phototaxic suppression: evaluation of a short-term memory assay in Drosophila melanogaster. Genes, Brain, and Behavior. 8: 377-89. PMID 19220479 DOI: 10.1111/j.1601-183X.2009.00483.x  1
2008 Kilduff TS, Lein ES, de la Iglesia H, Sakurai T, Fu YH, Shaw P. New developments in sleep research: molecular genetics, gene expression, and systems neurobiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11814-8. PMID 19005045 DOI: 10.1523/JNEUROSCI.3768-08.2008  1
2008 Seugnet L, Suzuki Y, Vine L, Gottschalk L, Shaw PJ. D1 receptor activation in the mushroom bodies rescues sleep-loss-induced learning impairments in Drosophila. Current Biology : Cb. 18: 1110-7. PMID 18674913 DOI: 10.1016/j.cub.2008.07.028  1
2008 Shaw P, Ocorr K, Bodmer R, Oldham S. Drosophila aging 2006/2007. Experimental Gerontology. 43: 5-10. PMID 18061385 DOI: 10.1016/j.exger.2007.10.008  1
2006 Seugnet L, Boero J, Gottschalk L, Duntley SP, Shaw PJ. Identification of a biomarker for sleep drive in flies and humans. Proceedings of the National Academy of Sciences of the United States of America. 103: 19913-8. PMID 17167051 DOI: 10.1073/pnas.0609463104  1
2006 Ganguly-Fitzgerald I, Donlea J, Shaw PJ. Waking experience affects sleep need in Drosophila. Science (New York, N.Y.). 313: 1775-81. PMID 16990546 DOI: 10.1126/science.1130408  1
2006 Dissel S, Shaw PJ. Drosophila model systems for genetic sleep research The Genetic Basis of Sleep and Sleep Disorders. 43-53. DOI: 10.1017/CBO9781139649469.007  1
2005 Andretic R, Shaw PJ. Essentials of sleep recordings in Drosophila: moving beyond sleep time. Methods in Enzymology. 393: 759-72. PMID 15817323 DOI: 10.1016/S0076-6879(05)93040-1  1
2003 Shaw P. Awakening to the behavioral analysis of sleep in Drosophila Journal of Biological Rhythms. 18: 4-11. PMID 12568240 DOI: 10.1177/0748730402239672  1
2003 Shaw PJ, Franken P. Perchance to dream: solving the mystery of sleep through genetic analysis. Journal of Neurobiology. 54: 179-202. PMID 12486704 DOI: 10.1002/neu.10167  1
2002 Shaw PJ, Tononi G, Greenspan RJ, Robinson DF. Stress response genes protect against lethal effects of sleep deprivation in Drosophila. Nature. 417: 287-91. PMID 12015603 DOI: 10.1038/417287a  1
2001 Greenspan RJ, Tononi G, Cirelli C, Shaw PJ. Sleep and the fruit fly. Trends in Neurosciences. 24: 142-5. PMID 11182453 DOI: 10.1016/S0166-2236(00)01719-7  1
2000 Shaw PJ, Cirelli C, Greenspan RJ, Tononi G. Correlates of sleep and waking in Drosophila melanogaster. Science (New York, N.Y.). 287: 1834-7. PMID 10710313  1
1999 Cirelli C, Shaw PJ, Rechtschaffen A, Tononi G. No evidence of brain cell degeneration after long-term sleep deprivation in rats. Brain Research. 840: 184-93. PMID 10517970 DOI: 10.1016/S0006-8993(99)01768-0  1
1998 Shaw PJ, Bergmann BM, Rechtschaffen A. Effects of paradoxical sleep deprivation on thermoregulation in the rat. Sleep. 21: 7-17. PMID 9485528  1
1997 Shaw PJ, Bergmann BM, Rechtschaffen A. Operant control of ambient temperature during sleep deprivation. The American Journal of Physiology. 272: R682-90. PMID 9124495  1
1996 Bergmann BM, Gilliland MA, Feng PF, Russell DR, Shaw P, Wright M, Rechtschaffen A, Alverdy JC. Are physiological effects of sleep deprivation in the rat mediated by bacterial invasion? Sleep. 19: 554-62. PMID 8899934  1
1995 Feng PF, Shaw P, Bergmann BM, Obermeyer W, Tsai LL, Zenko CE, Rechtschaffen A. Sleep deprivation in the rat: XX. Differences in wake and sleep temperatures during recovery. Sleep. 18: 797-804. PMID 8638074  1
1981 Shaw PJ. A peak profile analysis procedure for extracting unit cell transform data from the Fourier transforms of periodic arrays Journal of Cell Science. 51: 314-321. PMID 7320087  1
Low-probability matches
2015 Kaufmann U, Shaw PJ, Kozhaya L, Subramanian R, Gaida K, Unutmaz D, McBride HJ, Feske S. Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 26673135 DOI: 10.4049/jimmunol.1501406  0.08
2015 Highley JR, Lorente Pons A, Cooper-Knock J, Wharton SB, Ince PG, Shaw PJ, Wood J, Kirby J. Motor neurone disease/amyotrophic lateral sclerosis associated with intermediate length CAG repeat expansions in Ataxin-2 does not have 1C2-positive polyglutamine inclusions. Neuropathology and Applied Neurobiology. PMID 26095883 DOI: 10.1111/nan.12254  0.04
2015 Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD. The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells. Immunity. 42: 654-64. PMID 25888258 DOI: 10.1016/j.immuni.2015.03.006  0.08
2014 Shaw PJ, Weidinger C, Vaeth M, Luethy K, Kaech SM, Feske S. CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2. The Journal of Clinical Investigation. 124: 4549-63. PMID 25157823 DOI: 10.1172/JCI76602  0.08
2013 Waite JC, Vardhana S, Shaw PJ, Jang JE, McCarl CA, Cameron TO, Feske S, Dustin ML. Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo. European Journal of Immunology. 43: 3343-54. PMID 23939929 DOI: 10.1002/eji.201243255  0.08
2013 Weidinger C, Shaw PJ, Feske S. STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells. Embo Molecular Medicine. 5: 1311-21. PMID 23922331 DOI: 10.1002/emmm.201302989  0.08
2013 Shaw PJ, Qu B, Hoth M, Feske S. Molecular regulation of CRAC channels and their role in lymphocyte function. Cellular and Molecular Life Sciences : Cmls. 70: 2637-56. PMID 23052215 DOI: 10.1007/s00018-012-1175-2  0.08
2012 Ippagunta SK, Malireddi RK, Shaw PJ, Neale GA, Vande Walle L, Fukui Y, Green DR, Lamkanfi M, Kanneganti TD. Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines. Nature Immunology. 13: 701-2. PMID 22905357 DOI: 10.1038/ni.2389  0.08
2012 Shaw PJ, Feske S. Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity. The Journal of Physiology. 590: 4157-67. PMID 22615435 DOI: 10.1113/jphysiol.2012.233221  0.08
2012 Shaw PJ, Feske S. Physiological and pathophysiological functions of SOCE in the immune system. Frontiers in Bioscience (Elite Edition). 4: 2253-68. PMID 22202035  0.08
2011 Quan SF, Shaw PJ, Naidoo N, Haeggström E, Krueger JM, Church GM. Panel discussion: can there be a biomarker for sleepiness? Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 7: S45-8. PMID 22003333 DOI: 10.5664/JCSM.1364  0.08
2011 Ippagunta SK, Malireddi RK, Shaw PJ, Neale GA, Vande Walle L, Green DR, Fukui Y, Lamkanfi M, Kanneganti TD. The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization. Nature Immunology. 12: 1010-6. PMID 21892172 DOI: 10.1038/ni.2095  0.08
2011 van de Veerdonk FL, Joosten LA, Shaw PJ, Smeekens SP, Malireddi RK, van der Meer JW, Kullberg BJ, Netea MG, Kanneganti TD. The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis. European Journal of Immunology. 41: 2260-8. PMID 21681738 DOI: 10.1002/eji.201041226  0.08
2011 Shaw PJ, Barr MJ, Lukens JR, McGargill MA, Chi H, Mak TW, Kanneganti TD. Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity. Immunity. 34: 75-84. PMID 21236705 DOI: 10.1016/j.immuni.2010.12.015  0.08
2010 Shaw PJ, Ganey PE, Roth RA. Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 7-18. PMID 20538741 DOI: 10.1093/toxsci/kfq168  0.08
2010 Shaw PJ, Lukens JR, Burns S, Chi H, McGargill MA, Kanneganti TD. Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 184: 4610-4. PMID 20368281 DOI: 10.4049/jimmunol.1000217  0.08
2009 Shaw PJ, Beggs KM, Sparkenbaugh EM, Dugan CM, Ganey PE, Roth RA. Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 111: 288-301. PMID 19638433 DOI: 10.1093/toxsci/kfp163  0.08
2009 Shaw PJ, Fullerton AM, Scott MA, Ganey PE, Roth RA. The role of the hemostatic system in murine liver injury induced by coexposure to lipopolysaccharide and trovafloxacin, a drug with idiosyncratic liability. Toxicology and Applied Pharmacology. 236: 293-300. PMID 19367693 DOI: 10.1016/j.taap.2009.01.018  0.08
2009 Shaw PJ, Ganey PE, Roth RA. Trovafloxacin enhances the inflammatory response to a Gram-negative or a Gram-positive bacterial stimulus, resulting in neutrophil-dependent liver injury in mice. The Journal of Pharmacology and Experimental Therapeutics. 330: 72-8. PMID 19351866 DOI: 10.1124/jpet.109.151068  0.08
2009 Shaw PJ, Ditewig AC, Waring JF, Liguori MJ, Blomme EA, Ganey PE, Roth RA. Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury. Toxicological Sciences : An Official Journal of the Society of Toxicology. 107: 270-80. PMID 18930950 DOI: 10.1093/toxsci/kfn205  0.08
2009 Shaw PJ, Ganey PE, Roth RA. Tumor necrosis factor alpha is a proximal mediator of synergistic hepatotoxicity from trovafloxacin/lipopolysaccharide coexposure. The Journal of Pharmacology and Experimental Therapeutics. 328: 62-8. PMID 18820134 DOI: 10.1124/jpet.108.143792  0.08
2007 Shaw PJ, Hopfensperger MJ, Ganey PE, Roth RA. Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 259-66. PMID 17709330 DOI: 10.1093/toxsci/kfm218  0.08
2005 Luyendyk JP, Shaw PJ, Green CD, Maddox JF, Ganey PE, Roth RA. Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine. The Journal of Pharmacology and Experimental Therapeutics. 314: 1023-31. PMID 15933155 DOI: 10.1124/jpet.105.087981  0.08
2015 Pancani S, Rowson J, Tindale W, Heron N, Langley J, McCarthy AD, Quinn A, Reed H, Stanton A, Shaw PJ, McDermott CJ, Mazzà C. Assessment of the Sheffield Support Snood, an innovative cervical orthosis designed for people affected by neck muscle weakness. Clinical Biomechanics (Bristol, Avon). PMID 26673978 DOI: 10.1016/j.clinbiomech.2015.11.010  0.04
2015 Baker DJ, Blackburn DJ, Keatinge M, Sokhi D, Viskaitis P, Heath PR, Ferraiuolo L, Kirby J, Shaw PJ. Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis. Frontiers in Cellular Neuroscience. 9: 410. PMID 26528138 DOI: 10.3389/fncel.2015.00410  0.04
2015 Rafiq MK, Shaw PJ. Cough assistance to clear lungs of ALS patients with severe bulbar dysfunction: Not a good idea! Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-2. PMID 26471227 DOI: 10.3109/21678421.2015.1099676  0.04
2015 Fluteau A, Ince PG, Minett T, Matthews FE, Brayne C, Garwood CJ, Ratcliffe LE, Morgan S, Heath PR, Shaw PJ, Wharton SB, Simpson JE. The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain. Neuroscience Letters. 609: 11-17. PMID 26455863 DOI: 10.1016/j.neulet.2015.10.001  0.04
2015 Wong CH, Topp S, Gkazi AS, Troakes C, Miller JW, de Majo M, Kirby J, Shaw PJ, Morrison KE, de Belleroche J, Vance CA, Al-Chalabi A, Al-Sarraj S, Shaw CE, Smith BN. The CHCHD10 P34S variant is not associated with ALS in a UK cohort of familial and sporadic patients. Neurobiology of Aging. 36: 2908.e17-8. PMID 26344877 DOI: 10.1016/j.neurobiolaging.2015.07.014  0.04
2015 Allen SP, Duffy LM, Shaw PJ, Grierson AJ. Altered age-related changes in bioenergetic properties and mitochondrial morphology in fibroblasts from sporadic amyotrophic lateral sclerosis patients. Neurobiology of Aging. 36: 2893-903. PMID 26344876 DOI: 10.1016/j.neurobiolaging.2015.07.013  0.04
2015 Bury JJ, Highley JR, Cooper-Knock J, Goodall EF, Higginbottom A, McDermott CJ, Ince PG, Shaw PJ, Kirby J. Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 26303227 DOI: 10.1111/neup.12240  0.04
2015 Smith L, Cupid BC, Dickie BG, Al-Chalabi A, Morrison KE, Shaw CE, Shaw PJ. Establishing the UK DNA Bank for motor neuron disease (MND). Bmc Genetics. 16: 84. PMID 26170009 DOI: 10.1186/s12863-015-0236-6  0.04
2015 Rafiq MK, Lee E, Bradburn M, McDermott CJ, Shaw PJ. Effect of lipid profile on prognosis in the patients with amyotrophic lateral sclerosis: Insights from the olesoxime clinical trial. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-7. PMID 26161993 DOI: 10.3109/21678421.2015.1062517  0.04
2015 Rafiq MK, Bradburn M, Proctor AR, Billings CG, Bianchi S, McDermott CJ, Shaw PJ. A preliminary randomized trial of the mechanical insufflator-exsufflator versus breath-stacking technique in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 26140500 DOI: 10.3109/21678421.2015.1051992  0.04
2015 Simpson JE, Ince PG, Minett T, Matthews FE, Heath PR, Shaw PJ, Goodall E, Garwood CJ, Ratcliffe LE, Brayne C, Rattray M, Wharton SB. Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology. Neuropathology and Applied Neurobiology. PMID 26095650 DOI: 10.1111/nan.12252  0.04
2015 van der Kleij LA, Jones AR, Steen IN, Young CA, Shaw PJ, Shaw CE, Leigh PN, Turner MR, Al-Chalabi A. Regionality of disease progression predicts prognosis in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-6. PMID 26083873 DOI: 10.3109/21678421.2015.1051987  0.04
2015 Scarrott JM, Herranz-Martín S, Alrafiah AR, Shaw PJ, Azzouz M. Current developments in gene therapy for amyotrophic lateral sclerosis. Expert Opinion On Biological Therapy. 15: 935-47. PMID 25959569 DOI: 10.1517/14712598.2015.1044894  0.04
2015 Cooper-Knock J, Higginbottom A, Stopford MJ, Highley JR, Ince PG, Wharton SB, Pickering-Brown S, Kirby J, Hautbergue GM, Shaw PJ. Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy. Acta Neuropathologica. 130: 63-75. PMID 25943887 DOI: 10.1007/s00401-015-1429-9  0.04
2015 Lill CM, Rengmark A, Pihlstrøm L, Fogh I, Shatunov A, Sleiman PM, Wang LS, Liu T, Lassen CF, Meissner E, Alexopoulos P, Calvo A, Chio A, Dizdar N, Faltraco F, ... ... Shaw PJ, et al. The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25936935 DOI: 10.1016/j.jalz.2014.12.009  0.04
2015 Nicholls Z, Hobson E, Martindale J, Shaw PJ. Diagnosis of spinal xanthomatosis by next-generation sequencing: identifying a rare, treatable mimic of hereditary spastic paraparesis. Practical Neurology. 15: 280-3. PMID 25862734 DOI: 10.1136/practneurol-2015-001117  0.04
2015 Jones AR, Troakes C, King A, Sahni V, De Jong S, Bossers K, Papouli E, Mirza M, Al-Sarraj S, Shaw CE, Shaw PJ, Kirby J, Veldink JH, Macklis JD, Powell JF, et al. Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes. Neurobiology of Aging. 36: 2006.e1-9. PMID 25801576 DOI: 10.1016/j.neurobiolaging.2015.02.017  0.04
2015 Cooper-Knock J, Kirby J, Highley R, Shaw PJ. The Spectrum of C9orf72-mediated Neurodegeneration and Amyotrophic Lateral Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 326-39. PMID 25731823 DOI: 10.1007/s13311-015-0342-1  0.04
2015 Mathur R, Ince PG, Minett T, Garwood CJ, Shaw PJ, Matthews FE, Brayne C, Simpson JE, Wharton SB. A reduced astrocyte response to β-amyloid plaques in the ageing brain associates with cognitive impairment. Plos One. 10: e0118463. PMID 25707004 DOI: 10.1371/journal.pone.0118463  0.04
2015 Simpson JE, Ince PG, Matthews FE, Shaw PJ, Heath PR, Brayne C, Garwood C, Higginbottom A, Wharton SB. A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort. Neuropathology and Applied Neurobiology. 41: 483-96. PMID 25443110 DOI: 10.1111/nan.12202  0.04
2015 Beer AM, Cooper-Knock J, Higginbottom A, Highley JR, Wharton SB, Ince PG, Milano A, Jones AA, Al-Chalabi A, Kirby J, Shaw PJ. Intermediate length C9orf72 expansion in an ALS patient without classical C9orf72 neuropathology. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 16: 249-51. PMID 25436637 DOI: 10.3109/21678421.2014.977296  0.04
2015 Walsh MJ, Cooper-Knock J, Dodd JE, Stopford MJ, Mihaylov SR, Kirby J, Shaw PJ, Hautbergue GM. Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art. Neuropathology and Applied Neurobiology. 41: 109-34. PMID 25319671 DOI: 10.1111/nan.12187  0.04
2015 McGeachan AJ, Hobson EV, Shaw PJ, McDermott CJ. Developing an outcome measure for excessive saliva management in MND and an evaluation of saliva burden in Sheffield. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 16: 108-13. PMID 25225845 DOI: 10.3109/21678421.2014.951942  0.04
2015 Marino M, Papa S, Crippa V, Nardo G, Peviani M, Cheroni C, Trolese MC, Lauranzano E, Bonetto V, Poletti A, DeBiasi S, Ferraiuolo L, Shaw PJ, Bendotti C. Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis. Neurobiology of Aging. 36: 492-504. PMID 25085783 DOI: 10.1016/j.neurobiolaging.2014.06.026  0.04
2015 Raman R, Allen SP, Goodall EF, Kramer S, Ponger LL, Heath PR, Milo M, Hollinger HC, Walsh T, Highley JR, Olpin S, McDermott CJ, Shaw PJ, Kirby J. Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions. Neuropathology and Applied Neurobiology. 41: 201-26. PMID 24750211 DOI: 10.1111/nan.12147  0.04
2015 Balendra R, Jones A, Jivraj N, Steen IN, Young CA, Shaw PJ, Turner MR, Leigh PN, Al-Chalabi A. Use of clinical staging in amyotrophic lateral sclerosis for phase 3 clinical trials. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 45-9. PMID 24463480 DOI: 10.1136/jnnp-2013-306865  0.04
2015 McDermott CJ, Shaw PJ, Cooper CL, Dixon S, Baird WO, Bradburn MJ, Fitzgerald P, Maguire C, Baxter SK, Williams T, Baudouin SV, Karat D, Talbot K, Stradling J, Maynard N, et al. Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): A multicentre, open-label, randomised controlled trial The Lancet Neurology. 14: 883-892. DOI: 10.1016/S1474-4422(15)00152-0  0.04
2014 Reed H, Langley J, Stanton A, Heron N, Clarke Z, Judge S, McCarthy A, Squire G, Quinn A, Wells O, Tindale W, Baxter S, Shaw PJ, McDermott CJ. Head-Up; An interdisciplinary, participatory and co-design process informing the development of a novel head and neck support for people living with progressive neck muscle weakness. Journal of Medical Engineering & Technology. 39: 404-10. PMID 26453038 DOI: 10.3109/03091902.2015.1088092  0.04
2014 Smith BN, Ticozzi N, Fallini C, Gkazi AS, Topp S, Kenna KP, Scotter EL, Kost J, Keagle P, Miller JW, Calini D, Vance C, Danielson EW, Troakes C, Tiloca C, ... ... Shaw PJ, et al. Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS. Neuron. 84: 324-31. PMID 25374358 DOI: 10.1016/j.neuron.2014.09.027  0.04
2014 Bennett EJ, Mead RJ, Azzouz M, Shaw PJ, Grierson AJ. Early detection of motor dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis (ALS) using home cage running wheels. Plos One. 9: e107918. PMID 25268710 DOI: 10.1371/journal.pone.0107918  0.04
2014 Ramesh TM, Shaw PJ, McDearmid J. A zebrafish model exemplifies the long preclinical period of motor neuron disease. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 1288-9. PMID 24970908 DOI: 10.1136/jnnp-2014-308288  0.04
2014 Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J, Hautbergue GM, Shaw PJ. Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions. Brain : a Journal of Neurology. 137: 2040-51. PMID 24866055 DOI: 10.1093/brain/awu120  0.04
2014 Garwood CJ, Simpson JE, Al Mashhadi S, Axe C, Wilson S, Heath PR, Shaw PJ, Matthews FE, Brayne C, Ince PG, Wharton SB. DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort. Neuropathology and Applied Neurobiology. 40: 802-14. PMID 24861546 DOI: 10.1111/nan.12156  0.04
2014 Stavroulakis T, Baird WO, Baxter SK, Walsh T, Shaw PJ, McDermott CJ. The impact of gastrostomy in motor neurone disease: challenges and benefits from a patient and carer perspective. Bmj Supportive & Palliative Care. PMID 24848262 DOI: 10.1136/bmjspcare-2013-000609  0.04
2014 Highley JR, Kirby J, Jansweijer JA, Webb PS, Hewamadduma CA, Heath PR, Higginbottom A, Raman R, Ferraiuolo L, Cooper-Knock J, McDermott CJ, Wharton SB, Shaw PJ, Ince PG. Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones. Neuropathology and Applied Neurobiology. 40: 670-85. PMID 24750229 DOI: 10.1111/nan.12148  0.04
2014 Stavroulakis T, Baird WO, Baxter SK, Walsh T, Shaw PJ, McDermott CJ. Factors influencing decision-making in relation to timing of gastrostomy insertion in patients with motor neurone disease. Bmj Supportive & Palliative Care. 4: 57-63. PMID 24644772 DOI: 10.1136/bmjspcare-2013-000497  0.04
2014 Jones AR, Jivraj N, Balendra R, Murphy C, Kelly J, Thornhill M, Young C, Shaw PJ, Leigh PN, Turner MR, Steen IN, McCrone P, Al-Chalabi A. Health utility decreases with increasing clinical stage in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 285-91. PMID 24641613 DOI: 10.3109/21678421.2013.872149  0.04
2014 Savage AL, Wilm TP, Khursheed K, Shatunov A, Morrison KE, Shaw PJ, Shaw CE, Smith B, Breen G, Al-Chalabi A, Moss D, Bubb VJ, Quinn JP. An evaluation of a SVA retrotransposon in the FUS promoter as a transcriptional regulator and its association to ALS. Plos One. 9: e90833. PMID 24608899 DOI: 10.1371/journal.pone.0090833  0.04
2014 Yang DJ, Wang XL, Ismail A, Ashman CJ, Valori CF, Wang G, Gao S, Higginbottom A, Ince PG, Azzouz M, Xu J, Shaw PJ, Ning K. PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons. Cell Death & Disease. 5: e1096. PMID 24577094 DOI: 10.1038/cddis.2014.55  0.04
2014 Cooper-Knock J, Shaw PJ, Kirby J. The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype. Acta Neuropathologica. 127: 333-45. PMID 24493408 DOI: 10.1007/s00401-014-1251-9  0.04
2014 Bayatti N, Cooper-Knock J, Bury JJ, Wyles M, Heath PR, Kirby J, Shaw PJ. Comparison of blood RNA extraction methods used for gene expression profiling in amyotrophic lateral sclerosis. Plos One. 9: e87508. PMID 24475299 DOI: 10.1371/journal.pone.0087508  0.04
2014 Lenglet T, Lacomblez L, Abitbol JL, Ludolph A, Mora JS, Robberecht W, Shaw PJ, Pruss RM, Cuvier V, Meininger V. A phase II-III trial of olesoxime in subjects with amyotrophic lateral sclerosis. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 21: 529-36. PMID 24447620 DOI: 10.1111/ene.12344  0.04
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/s00401-013-1239-x  0.04
2014 Allen SP, Rajan S, Duffy L, Mortiboys H, Higginbottom A, Grierson AJ, Shaw PJ. Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis. Neurobiology of Aging. 35: 1499-509. PMID 24439480 DOI: 10.1016/j.neurobiolaging.2013.11.025  0.04
2014 Meyer K, Ferraiuolo L, Miranda CJ, Likhite S, McElroy S, Renusch S, Ditsworth D, Lagier-Tourenne C, Smith RA, Ravits J, Burghes AH, Shaw PJ, Cleveland DW, Kolb SJ, Kaspar BK. Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS. Proceedings of the National Academy of Sciences of the United States of America. 111: 829-32. PMID 24379375 DOI: 10.1073/pnas.1314085111  0.04
2014 Wood-Allum CA, Shaw PJ. Thyroid disease and the nervous system. Handbook of Clinical Neurology. 120: 703-35. PMID 24365348 DOI: 10.1016/B978-0-7020-4087-0.00048-6  0.04
2014 Fogh I, Ratti A, Gellera C, Lin K, Tiloca C, Moskvina V, Corrado L, Sorarù G, Cereda C, Corti S, Gentilini D, Calini D, Castellotti B, Mazzini L, Querin G, ... ... Shaw PJ, et al. A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 23: 2220-31. PMID 24256812 DOI: 10.1093/hmg/ddt587  0.04
2014 Da Costa MM, Allen CE, Higginbottom A, Ramesh T, Shaw PJ, McDermott CJ. A new zebrafish model produced by TILLING of SOD1-related amyotrophic lateral sclerosis replicates key features of the disease and represents a tool for in vivo therapeutic screening. Disease Models & Mechanisms. 7: 73-81. PMID 24092880 DOI: 10.1242/dmm.012013  0.04
2013 Heath PR, Kirby J, Shaw PJ. Investigating cell death mechanisms in amyotrophic lateral sclerosis using transcriptomics. Frontiers in Cellular Neuroscience. 7: 259. PMID 24381542 DOI: 10.3389/fncel.2013.00259  0.04
2013 Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ, McDermott CJ. The impact on the family carer of motor neurone disease and intervention with noninvasive ventilation. Journal of Palliative Medicine. 16: 1602-9. PMID 24236958 DOI: 10.1089/jpm.2013.0211  0.04
2013 Christou YA, Ohyama K, Placzek M, Monk PN, Shaw PJ. Wild-type but not mutant SOD1 transgenic astrocytes promote the efficient generation of motor neuron progenitors from mouse embryonic stem cells. Bmc Neuroscience. 14: 126. PMID 24134124 DOI: 10.1186/1471-2202-14-126  0.04
2013 Goodall EF, Heath PR, Bandmann O, Kirby J, Shaw PJ. Neuronal dark matter: the emerging role of microRNAs in neurodegeneration. Frontiers in Cellular Neuroscience. 7: 178. PMID 24133413 DOI: 10.3389/fncel.2013.00178  0.04
2013 Cooper-Knock J, Higginbottom A, Connor-Robson N, Bayatti N, Bury JJ, Kirby J, Ninkina N, Buchman VL, Shaw PJ. C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles. Neurology. 81: 1719-21. PMID 24107864 DOI: 10.1212/01.wnl.0000435295.41974.2e  0.04
2013 Nardo G, Iennaco R, Fusi N, Heath PR, Marino M, Trolese MC, Ferraiuolo L, Lawrence N, Shaw PJ, Bendotti C. Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 136: 3305-32. PMID 24065725 DOI: 10.1093/brain/awt250  0.04
2013 Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ, McDermott CJ. Use of non-invasive ventilation at end of life. Palliative Medicine. 27: 878. PMID 24058005 DOI: 10.1177/0269216313495098  0.04
2013 Gibbons CJ, Thornton EW, Ealing J, Shaw PJ, Talbot K, Tennant A, Young CA. Assessing social isolation in motor neurone disease: a Rasch analysis of the MND Social Withdrawal Scale. Journal of the Neurological Sciences. 334: 112-8. PMID 24011605 DOI: 10.1016/j.jns.2013.08.002  0.04
2013 Cooper-Knock J, Frolov A, Highley JR, Charlesworth G, Kirby J, Milano A, Hartley J, Ince PG, McDermott CJ, Lashley T, Revesz T, Shaw PJ, Wood NW, Bandmann O. C9ORF72 expansions, parkinsonism, and Parkinson disease: a clinicopathologic study. Neurology. 81: 808-11. PMID 23884045 DOI: 10.1212/WNL.0b013e3182a2cc38  0.04
2013 Richardson K, Allen SP, Mortiboys H, Grierson AJ, Wharton SB, Ince PG, Shaw PJ, Heath PR. The effect of SOD1 mutation on cellular bioenergetic profile and viability in response to oxidative stress and influence of mutation-type. Plos One. 8: e68256. PMID 23840839 DOI: 10.1371/journal.pone.0068256  0.04
2013 Jenkins TM, Burness C, Connolly DJ, Rao DG, Hoggard N, Mawson S, McDermott CJ, Wilkinson ID, Shaw PJ. A prospective pilot study measuring muscle volumetric change in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 414-23. PMID 23705876 DOI: 10.3109/21678421.2013.795597  0.04
2013 Turner MR, Bowser R, Bruijn L, Dupuis L, Ludolph A, McGrath M, Manfredi G, Maragakis N, Miller RG, Pullman SL, Rutkove SB, Shaw PJ, Shefner J, Fischbeck KH. Mechanisms, models and biomarkers in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 19-32. PMID 23678877 DOI: 10.3109/21678421.2013.778554  0.04
2013 Hobson EV, McGeachan A, Al-Chalabi A, Chandran S, Crawley F, Dick D, Donaghy C, Ealing J, Ellis CM, Gorrie G, Hanemann CO, Harrower T, Jung A, Majeed T, Malaspina A, ... ... Shaw PJ, et al. Management of sialorrhoea in motor neuron disease: a survey of current UK practice. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 521-7. PMID 23647474 DOI: 10.3109/21678421.2013.790452  0.04
2013 Mok K, Laaksovirta H, Tienari PJ, Peuralinna T, Myllykangas L, Chiò A, Traynor BJ, Nalls MA, Gurunlian N, Shatunov A, Restagno G, Mora G, Nigel Leigh P, Shaw CE, Morrison KE, ... Shaw PJ, et al. Homozygosity analysis in amyotrophic lateral sclerosis. European Journal of Human Genetics : Ejhg. 21: 1429-35. PMID 23612577 DOI: 10.1038/ejhg.2013.59  0.04
2013 Mead RJ, Higginbottom A, Allen SP, Kirby J, Bennett E, Barber SC, Heath PR, Coluccia A, Patel N, Gardner I, Brancale A, Grierson AJ, Shaw PJ. S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis. Free Radical Biology & Medicine. 61: 438-52. PMID 23608463 DOI: 10.1016/j.freeradbiomed.2013.04.018  0.04
2013 Sarkozy A, Hicks D, Hudson J, Laval SH, Barresi R, Hilton-Jones D, Deschauer M, Harris E, Rufibach L, Hwang E, Bashir R, Walter MC, Krause S, van den Bergh P, Illa I, ... ... Shaw PJ, et al. ANO5 gene analysis in a large cohort of patients with anoctaminopathy: confirmation of male prevalence and high occurrence of the common exon 5 gene mutation. Human Mutation. 34: 1111-8. PMID 23606453 DOI: 10.1002/humu.22342  0.04
2013 Garcia MC, Chapman JR, Shaw PJ, Gottlieb DJ, Ralph A, Craig JC, Tong A. Motivations, experiences, and perspectives of bone marrow and peripheral blood stem cell donors: thematic synthesis of qualitative studies. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 1046-58. PMID 23603456 DOI: 10.1016/j.bbmt.2013.04.012  0.01
2013 Jones AR, Woollacott I, Shatunov A, Cooper-Knock J, Buchman V, Sproviero W, Smith B, Scott KM, Balendra R, Abel O, McGuffin P, Ellis CM, Shaw PJ, Morrison KE, Farmer A, et al. Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat. Neurobiology of Aging. 34: 2234.e1-7. PMID 23587638 DOI: 10.1016/j.neurobiolaging.2013.03.003  0.04
2013 Buchman VL, Cooper-Knock J, Connor-Robson N, Higginbottom A, Kirby J, Razinskaya OD, Ninkina N, Shaw PJ. Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation. Molecular Neurodegeneration. 8: 12. PMID 23566336 DOI: 10.1186/1750-1326-8-12  0.04
2013 Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ, McDermott CJ. The use of non-invasive ventilation at end of life in patients with motor neurone disease: a qualitative exploration of family carer and health professional experiences. Palliative Medicine. 27: 516-23. PMID 23462702 DOI: 10.1177/0269216313478449  0.04
2013 Hewamadduma CA, Grierson AJ, Ma TP, Pan L, Moens CB, Ingham PW, Ramesh T, Shaw PJ. Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish. Human Molecular Genetics. 22: 2376-86. PMID 23427147 DOI: 10.1093/hmg/ddt082  0.04
2013 Garwood C, Faizullabhoy A, Wharton SB, Ince PG, Heath PR, Shaw PJ, Baxter L, Gelsthorpe C, Forster G, Matthews FE, Brayne C, Simpson JE. Calcium dysregulation in relation to Alzheimer-type pathology in the ageing brain. Neuropathology and Applied Neurobiology. 39: 788-99. PMID 23421725 DOI: 10.1111/nan.12033  0.04
2013 Turner MR, Hardiman O, Benatar M, Brooks BR, Chio A, de Carvalho M, Ince PG, Lin C, Miller RG, Mitsumoto H, Nicholson G, Ravits J, Shaw PJ, Swash M, Talbot K, et al. Controversies and priorities in amyotrophic lateral sclerosis. The Lancet. Neurology. 12: 310-22. PMID 23415570 DOI: 10.1016/S1474-4422(13)70036-X  0.04
2013 McGown A, McDearmid JR, Panagiotaki N, Tong H, Al Mashhadi S, Redhead N, Lyon AN, Beattie CE, Shaw PJ, Ramesh TM. Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model. Annals of Neurology. 73: 246-58. PMID 23281025 DOI: 10.1002/ana.23780  0.04
2013 Kirby J, Highley JR, Cox L, Goodall EF, Hewitt C, Hartley JA, Hollinger HC, Fox M, Ince PG, McDermott CJ, Shaw PJ. Lack of unique neuropathology in amyotrophic lateral sclerosis associated with p.K54E angiogenin (ANG) mutation. Neuropathology and Applied Neurobiology. 39: 562-71. PMID 23228179 DOI: 10.1111/nan.12007  0.04
2013 Brockington A, Ning K, Heath PR, Wood E, Kirby J, Fusi N, Lawrence N, Wharton SB, Ince PG, Shaw PJ. Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity. Acta Neuropathologica. 125: 95-109. PMID 23143228 DOI: 10.1007/s00401-012-1058-5  0.04
2013 Ismail A, Cooper-Knock J, Highley JR, Milano A, Kirby J, Goodall E, Lowe J, Scott I, Constantinescu CS, Walters SJ, Price S, McDermott CJ, Sawcer S, Compston DA, Sharrack B, ... Shaw PJ, et al. Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 79-87. PMID 23085936 DOI: 10.1136/jnnp-2012-303326  0.04
2013 van Rheenen W, Diekstra FP, van Doormaal PT, Seelen M, Kenna K, McLaughlin R, Shatunov A, Czell D, van Es MA, van Vught PW, van Damme P, Smith BN, Waibel S, Schelhaas HJ, van der Kooi AJ, ... ... Shaw PJ, et al. H63D polymorphism in HFE is not associated with amyotrophic lateral sclerosis. Neurobiology of Aging. 34: 1517.e5-7. PMID 23063643 DOI: 10.1016/j.neurobiolaging.2012.07.020  0.04
2013 Stavroulakis T, Walsh T, Shaw PJ, McDermott CJ. Gastrostomy use in motor neurone disease (MND): a review, meta-analysis and survey of current practice. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 96-104. PMID 22985431 DOI: 10.3109/17482968.2012.723722  0.04
2013 Baxter SK, Baird WO, Thompson S, Bianchi SM, Walters SJ, Lee E, Ahmedzai SH, Proctor A, Shaw PJ, McDermott CJ. The initiation of non-invasive ventilation for patients with motor neuron disease: patient and carer perceptions of obstacles and outcomes. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 105-10. PMID 22953736 DOI: 10.3109/17482968.2012.719238  0.04
2013 Smith BN, Newhouse S, Shatunov A, Vance C, Topp S, Johnson L, Miller J, Lee Y, Troakes C, Scott KM, Jones A, Gray I, Wright J, Hortobágyi T, Al-Sarraj S, ... ... Shaw PJ, et al. The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder. European Journal of Human Genetics : Ejhg. 21: 102-8. PMID 22692064 DOI: 10.1038/ejhg.2012.98  0.04
2013 Aridegbe T, Kandler R, Walters SJ, Walsh T, Shaw PJ, McDermott CJ. The natural history of motor neuron disease: assessing the impact of specialist care. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 13-9. PMID 22642305 DOI: 10.3109/17482968.2012.690419  0.04
2012 McDermott CJ, Maguire C, Cooper CL, Ackroyd R, Baird WO, Baudouin S, Bentley A, Bianchi S, Bourke S, Bradburn MJ, Dixon S, Ealing J, Galloway S, Karat D, Maynard N, ... ... Shaw PJ, et al. Protocol for diaphragm pacing in patients with respiratory muscle weakness due to motor neurone disease (DiPALS): a randomised controlled trial. Bmc Neurology. 12: 74. PMID 22897892 DOI: 10.1186/1471-2377-12-74  0.04
2012 Cooper-Knock J, Kirby J, Ferraiuolo L, Heath PR, Rattray M, Shaw PJ. Gene expression profiling in human neurodegenerative disease. Nature Reviews. Neurology. 8: 518-30. PMID 22890216 DOI: 10.1038/nrneurol.2012.156  0.04
2012 Rafiq MK, Bradburn M, Proctor AR, Billings C, Bianchi S, McDermott CJ, Shaw PJ. Using transcutaneous carbon dioxide monitor (TOSCA 500) to detect respiratory failure in patients with amyotrophic lateral sclerosis: a validation study. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 528-32. PMID 22871078 DOI: 10.3109/17482968.2012.688836  0.04
2012 Rafiq MK, Proctor AR, McDermott CJ, Shaw PJ. Respiratory management of motor neurone disease: a review of current practice and new developments. Practical Neurology. 12: 166-76. PMID 22661348 DOI: 10.1136/practneurol-2011-000199  0.04
2012 Bourke SC, O'Neill CL, Williams TL, Peel ET, Gibson GJ, McDermott CJ, Shaw PJ. The changing landscape of non-invasive ventilation in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 368-9. PMID 22399795 DOI: 10.1136/jnnp-2012-302253  0.04
2012 Cooper-Knock J, Hewitt C, Highley JR, Brockington A, Milano A, Man S, Martindale J, Hartley J, Walsh T, Gelsthorpe C, Baxter L, Forster G, Fox M, Bury J, Mok K, ... ... Shaw PJ, et al. Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72. Brain : a Journal of Neurology. 135: 751-64. PMID 22366792 DOI: 10.1093/brain/awr365  0.04
2012 Mok K, Traynor BJ, Schymick J, Tienari PJ, Laaksovirta H, Peuralinna T, Myllykangas L, Chiò A, Shatunov A, Boeve BF, Boxer AL, DeJesus-Hernandez M, Mackenzie IR, Waite A, Williams N, ... ... Shaw PJ, et al. Chromosome 9 ALS and FTD locus is probably derived from a single founder. Neurobiology of Aging. 33: 209.e3-8. PMID 21925771 DOI: 10.1016/j.neurobiolaging.2011.08.005  0.04
2012 O'Neill CL, Williams TL, Peel ET, McDermott CJ, Shaw PJ, Gibson GJ, Bourke SC. Non-invasive ventilation in motor neuron disease: an update of current UK practice. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 371-6. PMID 21849339 DOI: 10.1136/jnnp-2011-300480  0.04
2012 Harwood CA, McDermott CJ, Shaw PJ. Clinical aspects of motor neurone disease Medicine (United Kingdom). 40: 540-545. DOI: 10.1016/j.mpmed.2012.07.003  0.04
2011 Gibbons CJ, Mills RJ, Thornton EW, Ealing J, Mitchell JD, Shaw PJ, Talbot K, Tennant A, Young CA. Development of a patient reported outcome measure for fatigue in motor neurone disease: the Neurological Fatigue Index (NFI-MND). Health and Quality of Life Outcomes. 9: 101. PMID 22107756 DOI: 10.1186/1477-7525-9-101  0.04
2011 Ince PG, Highley JR, Kirby J, Wharton SB, Takahashi H, Strong MJ, Shaw PJ. Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology. Acta Neuropathologica. 122: 657-71. PMID 22105541 DOI: 10.1007/s00401-011-0913-0  0.04
2011 Ferraiuolo L, Kirby J, Grierson AJ, Sendtner M, Shaw PJ. Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nature Reviews. Neurology. 7: 616-30. PMID 22051914 DOI: 10.1038/nrneurol.2011.152  0.04
2011 Viggars AP, Wharton SB, Simpson JE, Matthews FE, Brayne C, Savva GM, Garwood C, Drew D, Shaw PJ, Ince PG. Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology: a study in the MRC-CFAS population neuropathology cohort. Neuroscience Letters. 505: 25-30. PMID 21970975 DOI: 10.1016/j.neulet.2011.09.049  0.04
2011 Gibbons CJ, Mills RJ, Thornton EW, Ealing J, Mitchell JD, Shaw PJ, Talbot K, Tennant A, Young CA. Rasch analysis of the hospital anxiety and depression scale (HADS) for use in motor neurone disease. Health and Quality of Life Outcomes. 9: 82. PMID 21955749 DOI: 10.1186/1477-7525-9-82  0.04
2011 Sargsyan SA, Blackburn DJ, Barber SC, Grosskreutz J, De Vos KJ, Monk PN, Shaw PJ. A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function. Bmc Neuroscience. 12: 91. PMID 21943126 DOI: 10.1186/1471-2202-12-91  0.04
2011 Al-Chalabi A, Shaw PJ, Young CA, Morrison KE, Murphy C, Thornhill M, Kelly J, Steen IN, Leigh PN. Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic lateral sclerosis (LiCALS) [Eudract number: 2008-006891-31]. Bmc Neurology. 11: 111. PMID 21936930 DOI: 10.1186/1471-2377-11-111  0.04
2011 Rafiq M, Sharrack N, Shaw PJ, Hadjivassiliou M. A neurological rarity not to be missed: cerebrotendinous xanthomatosis. Practical Neurology. 11: 296-300. PMID 21921005 DOI: 10.1136/practneurol-2011-000003  0.04
2011 Ferraiuolo L, Higginbottom A, Heath PR, Barber S, Greenald D, Kirby J, Shaw PJ. Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 134: 2627-41. PMID 21908873 DOI: 10.1093/brain/awr193  0.01
2011 Mead RJ, Bennett EJ, Kennerley AJ, Sharp P, Sunyach C, Kasher P, Berwick J, Pettmann B, Battaglia G, Azzouz M, Grierson A, Shaw PJ. Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS). Plos One. 6: e23244. PMID 21876739 DOI: 10.1371/journal.pone.0023244  0.04
2011 Simpson JE, Ince PG, Shaw PJ, Heath PR, Raman R, Garwood CJ, Gelsthorpe C, Baxter L, Forster G, Matthews FE, Brayne C, Wharton SB. Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype. Neurobiology of Aging. 32: 1795-807. PMID 21705112 DOI: 10.1016/j.neurobiolaging.2011.04.013  0.04
2011 Duffy LM, Chapman AL, Shaw PJ, Grierson AJ. Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis. Neuropathology and Applied Neurobiology. 37: 336-52. PMID 21299590 DOI: 10.1111/j.1365-2990.2011.01166.x  0.04
2010 Simpson JE, Wharton SB, Cooper J, Gelsthorpe C, Baxter L, Forster G, Shaw PJ, Savva G, Matthews FE, Brayne C, Ince PG. Alterations of the blood-brain barrier in cerebral white matter lesions in the ageing brain. Neuroscience Letters. 486: 246-51. PMID 20887772 DOI: 10.1016/j.neulet.2010.09.063  0.04
2010 Shatunov A, Mok K, Newhouse S, Weale ME, Smith B, Vance C, Johnson L, Veldink JH, van Es MA, van den Berg LH, Robberecht W, Van Damme P, Hardiman O, Farmer AE, Lewis CM, ... ... Shaw PJ, et al. Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. The Lancet. Neurology. 9: 986-94. PMID 20801717 DOI: 10.1016/S1474-4422(10)70197-6  0.04
2010 Hewitt C, Kirby J, Highley JR, Hartley JA, Hibberd R, Hollinger HC, Williams TL, Ince PG, McDermott CJ, Shaw PJ. Novel FUS/TLS mutations and pathology in familial and sporadic amyotrophic lateral sclerosis. Archives of Neurology. 67: 455-61. PMID 20385912 DOI: 10.1001/archneurol.2010.52  0.04
2010 Cox LE, Ferraiuolo L, Goodall EF, Heath PR, Higginbottom A, Mortiboys H, Hollinger HC, Hartley JA, Brockington A, Burness CE, Morrison KE, Wharton SB, Grierson AJ, Ince PG, Kirby J, ... Shaw PJ, et al. Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS). Plos One. 5: e9872. PMID 20352044 DOI: 10.1371/journal.pone.0009872  0.04
2010 Brockington A, Heath PR, Holden H, Kasher P, Bender FL, Claes F, Lambrechts D, Sendtner M, Carmeliet P, Shaw PJ. Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis. Bmc Genomics. 11: 203. PMID 20346106 DOI: 10.1186/1471-2164-11-203  0.04
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Shaw PJ, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/ng.536  0.04
2010 Turner MR, Brockington A, Scaber J, Hollinger H, Marsden R, Shaw PJ, Talbot K. Pattern of spread and prognosis in lower limb-onset ALS. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 369-73. PMID 20001488 DOI: 10.3109/17482960903420140  0.04
2010 Kirby J, Goodall EF, Smith W, Highley JR, Masanzu R, Hartley JA, Hibberd R, Hollinger HC, Wharton SB, Morrison KE, Ince PG, McDermott CJ, Shaw PJ. Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis. Neurogenetics. 11: 217-25. PMID 19760257 DOI: 10.1007/s10048-009-0218-9  0.04
2010 Simpson JE, Ince PG, Haynes LJ, Theaker R, Gelsthorpe C, Baxter L, Forster G, Lace GL, Shaw PJ, Matthews FE, Savva GM, Brayne C, Wharton SB. Population variation in oxidative stress and astrocyte DNA damage in relation to Alzheimer-type pathology in the ageing brain. Neuropathology and Applied Neurobiology. 36: 25-40. PMID 19422529 DOI: 10.1111/j.1365-2990.2009.01030.x  0.04
2010 Simpson JE, Ince PG, Lace G, Forster G, Shaw PJ, Matthews F, Savva G, Brayne C, Wharton SB. Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain. Neurobiology of Aging. 31: 578-90. PMID 18586353 DOI: 10.1016/j.neurobiolaging.2008.05.015  0.04
2009 Kim SH, Koroleva OA, Lewandowska D, Pendle AF, Clark GP, Simpson CG, Shaw PJ, Brown JW. Aberrant mRNA transcripts and the nonsense-mediated decay proteins UPF2 and UPF3 are enriched in the Arabidopsis nucleolus. The Plant Cell. 21: 2045-57. PMID 19602621 DOI: 10.1105/tpc.109.067736  0.01
2009 Kasher PR, De Vos KJ, Wharton SB, Manser C, Bennett EJ, Bingley M, Wood JD, Milner R, McDermott CJ, Miller CC, Shaw PJ, Grierson AJ. Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients. Journal of Neurochemistry. 110: 34-44. PMID 19453301 DOI: 10.1111/j.1471-4159.2009.06104.x  0.04
2009 Barber SC, Higginbottom A, Mead RJ, Barber S, Shaw PJ. An in vitro screening cascade to identify neuroprotective antioxidants in ALS. Free Radical Biology & Medicine. 46: 1127-38. PMID 19439221 DOI: 10.1016/j.freeradbiomed.2009.01.019  0.04
2009 Wharton SB, O'Callaghan JP, Savva GM, Nicoll JA, Matthews F, Simpson JE, Forster G, Shaw PJ, Brayne C, Ince PG. Population variation in glial fibrillary acidic protein levels in brain ageing: relationship to Alzheimer-type pathology and dementia. Dementia and Geriatric Cognitive Disorders. 27: 465-73. PMID 19420941 DOI: 10.1159/000217729  0.04
2009 Wills AM, Cronin S, Slowik A, Kasperaviciute D, Van Es MA, Morahan JM, Valdmanis PN, Meininger V, Melki J, Shaw CE, Rouleau GA, Fisher EM, Shaw PJ, Morrison KE, Pamphlett R, et al. A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS. Neurology. 73: 16-24. PMID 19321847 DOI: 10.1212/WNL.0b013e3181a18674  0.04
2009 Simpson JE, Hosny O, Wharton SB, Heath PR, Holden H, Fernando MS, Matthews F, Forster G, O'Brien JT, Barber R, Kalaria RN, Brayne C, Shaw PJ, Lewis CE, Ince PG, et al. Microarray RNA expression analysis of cerebral white matter lesions reveals changes in multiple functional pathways. Stroke; a Journal of Cerebral Circulation. 40: 369-75. PMID 19109541 DOI: 10.1161/STROKEAHA.108.529214  0.04
2009 Lambrechts D, Poesen K, Fernández-Santiago R, Al-Chalabi A, Del Bo R, Van Vught PW, Khan S, Marklund SL, Brockington A, van Marion I, Anneser J, Shaw C, Ludolph AC, Leigh NP, Comi GP, ... ... Shaw PJ, et al. Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the -2578AA genotype. Journal of Medical Genetics. 46: 840-6. PMID 18413368 DOI: 10.1136/jmg.2008.058222  0.04
2008 Selvarajah D, Wilkinson ID, Emery CJ, Shaw PJ, Griffiths PD, Gandhi R, Tesfaye S. Thalamic neuronal dysfunction and chronic sensorimotor distal symmetrical polyneuropathy in patients with type 1 diabetes mellitus. Diabetologia. 51: 2088-92. PMID 18773192 DOI: 10.1007/s00125-008-1139-0  0.04
2008 Nath CE, Earl JW, Pati N, Stephen K, Shaw PJ. Variability in the pharmacokinetics of intravenous busulphan given as a single daily dose to paediatric blood or marrow transplant recipients. British Journal of Clinical Pharmacology. 66: 50-9. PMID 18341668 DOI: 10.1111/j.1365-2125.2008.03166.x  0.01
2007 Simpson JE, Ince PG, Higham CE, Gelsthorpe CH, Fernando MS, Matthews F, Forster G, O'Brien JT, Barber R, Kalaria RN, Brayne C, Shaw PJ, Stoeber K, Williams GH, Lewis CE, et al. Microglial activation in white matter lesions and nonlesional white matter of ageing brains. Neuropathology and Applied Neurobiology. 33: 670-83. PMID 17990995 DOI: 10.1111/j.1365-2990.2007.00890.x  0.04
2007 De Vos KJ, Chapman AL, Tennant ME, Manser C, Tudor EL, Lau KF, Brownlees J, Ackerley S, Shaw PJ, McLoughlin DM, Shaw CE, Leigh PN, Miller CC, Grierson AJ. Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content. Human Molecular Genetics. 16: 2720-8. PMID 17725983 DOI: 10.1093/hmg/ddm226  0.04
2007 Kirby J, Hewamadduma CA, Hartley JA, Nixon HC, Evans H, Wadhwa RR, Kershaw C, Ince PG, Shaw PJ. Mutations in VAPB are not associated with sporadic ALS. Neurology. 68: 1951-3. PMID 17536055 DOI: 10.1212/01.wnl.0000263195.50981.a6  0.04
2007 Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, ... ... Shaw PJ, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Annals of Neurology. 61: 427-34. PMID 17469116 DOI: 10.1002/ana.21147  0.04
2007 Simpson JE, Fernando MS, Clark L, Ince PG, Matthews F, Forster G, O'Brien JT, Barber R, Kalaria RN, Brayne C, Shaw PJ, Lewis CE, Wharton SB. White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses. Neuropathology and Applied Neurobiology. 33: 410-9. PMID 17442062 DOI: 10.1111/j.1365-2990.2007.00828.x  0.04
2007 Kasperaviciute D, Weale ME, Shianna KV, Banks GT, Simpson CL, Hansen VK, Turner MR, Shaw CE, Al-Chalabi A, Pall HS, Goodall EF, Morrison KE, Orrell RW, Beck M, Jablonka S, ... ... Shaw PJ, et al. Large-scale pathways-based association study in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 130: 2292-301. PMID 17439985 DOI: 10.1093/brain/awm055  0.04
2007 Phoenix C, Taylor GA, Hartley J, Nixon H, Ince PG, Shaw PJ, Turnbull DM, Taylor RW. Investigation of the mitochondrial genome in patients with atypical motor neuron disease. Journal of Neurology. 254: 482-7. PMID 17401521 DOI: 10.1007/s00415-006-0399-1  0.04
2007 Chinnery PF, Mowbray C, Elliot H, Elson JL, Nixon H, Hartley J, Shaw PJ. Mitochondrial DNA haplogroups and amyotrophic lateral sclerosis. Neurogenetics. 8: 65-7. PMID 17082949 DOI: 10.1007/s10048-006-0066-9  0.04
2006 Wood JD, Landers JA, Bingley M, McDermott CJ, Thomas-McArthur V, Gleadall LJ, Shaw PJ, Cunliffe VT. The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo. Human Molecular Genetics. 15: 2763-71. PMID 16893913 DOI: 10.1093/hmg/ddl212  0.04
2006 Monk PN, Shaw PJ. ALS: life and death in a bad neighborhood. Nature Medicine. 12: 885-7. PMID 16892030 DOI: 10.1038/nm0806-885  0.04
2006 McDermott CJ, Burness CE, Kirby J, Cox LE, Rao DG, Hewamadduma C, Sharrack B, Hadjivassiliou M, Chinnery PF, Dalton A, Shaw PJ. Clinical features of hereditary spastic paraplegia due to spastin mutation. Neurology. 67: 45-51. PMID 16832076 DOI: 10.1212/01.wnl.0000223315.62404.00  0.04
2006 Parkinson N, Ince PG, Smith MO, Highley R, Skibinski G, Andersen PM, Morrison KE, Pall HS, Hardiman O, Collinge J, Shaw PJ, Fisher EM. ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). Neurology. 67: 1074-7. PMID 16807408 DOI: 10.1212/01.wnl.0000231510.89311.8b  0.04
2006 Fernando MS, Simpson JE, Matthews F, Brayne C, Lewis CE, Barber R, Kalaria RN, Forster G, Esteves F, Wharton SB, Shaw PJ, O'Brien JT, Ince PG. White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury. Stroke; a Journal of Cerebral Circulation. 37: 1391-8. PMID 16627790 DOI: 10.1161/01.STR.0000221308.94473.14  0.04
2006 Bourke SC, Tomlinson M, Williams TL, Bullock RE, Shaw PJ, Gibson GJ. Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial. The Lancet. Neurology. 5: 140-7. PMID 16426990 DOI: 10.1016/S1474-4422(05)70326-4  0.04
2005 Baron P, Bussini S, Cardin V, Corbo M, Conti G, Galimberti D, Scarpini E, Bresolin N, Wharton SB, Shaw PJ, Silani V. Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis. Muscle & Nerve. 32: 541-4. PMID 15962273 DOI: 10.1002/mus.20376  0.04
2018 Kirszenblat L, Ertekin D, Goodsell J, Zhou Y, Shaw PJ, van Swinderen B. Sleep regulates visual selective attention in . The Journal of Experimental Biology. PMID 30355611 DOI: 10.1242/jeb.191429  0.01
2018 Troup M, Yap MH, Rohrscheib C, Grabowska MJ, Ertekin D, Randeniya R, Kottler B, Larkin A, Munro K, Shaw P, van Swinderen B. Acute control of the sleep switch in reveals a role for gap junctions in regulating behavioral responsiveness. Elife. 7. PMID 30109983 DOI: 10.7554/eLife.37105  0.01
2017 Yap MHW, Grabowska MJ, Rohrscheib C, Jeans R, Troup M, Paulk AC, van Alphen B, Shaw PJ, van Swinderen B. Oscillatory brain activity in spontaneous and induced sleep stages in flies. Nature Communications. 8: 1815. PMID 29180766 DOI: 10.1038/s41467-017-02024-y  0.01
2017 Dissel S, Klose M, Donlea J, Cao L, English D, Winsky-Sommerer R, van Swinderen B, Shaw PJ. Enhanced sleep reverses memory deficits and underlying pathology in Drosophila models of Alzheimer's disease. Neurobiology of Sleep and Circadian Rhythms. 2: 15-26. PMID 29094110 DOI: 10.1016/j.nbscr.2016.09.001  0.01
2016 Dissel S, Shaw PJ. Neuroscience: Flipping the sleep switch. Nature. PMID 27487223 DOI: 10.1038/nature18918  0.01
2016 Neenan ST, Piper R, White PR, Kemp P, Leighton TG, Shaw PJ. Does Masking Matter? Shipping Noise and Fish Vocalizations. Advances in Experimental Medicine and Biology. 875: 747-753. PMID 26611028 DOI: 10.1007/978-1-4939-2981-8_91  0.01
2016 Hardman CJ, Harrison DPG, Shaw PJ, Nevard TD, Hughes B, Potts SG, Norris K. Supporting local diversity of habitats and species on farmland: A comparison of three wildlife-friendly schemes Journal of Applied Ecology. 53: 171-180. DOI: 10.1111/1365-2664.12557  0.01
2015 Shaw PJ, Kaewprommal P, Piriyapongsa J, Wongsombat C, Yuthavong Y, Kamchonwongpaisan S. Estimating mRNA lengths from Plasmodium falciparum genes by Virtual Northern RNA-seq analysis. International Journal For Parasitology. PMID 26548960 DOI: 10.1016/j.ijpara.2015.09.007  0.01
2015 Melnattur K, Dissel S, Shaw PJ. Learning and Memory: Do Bees Dream? Current Biology : Cb. 25: R1040-1. PMID 26528745 DOI: 10.1016/j.cub.2015.09.001  0.01
2015 Wangkumhang P, Wilantho A, Shaw PJ, Flori L, Moazami-Goudarzi K, Gautier M, Duangjinda M, Assawamakin A, Tongsima S. Genetic analysis of Thai cattle reveals a Southeast Asian indicine ancestry. Peerj. 3: e1318. PMID 26528405 DOI: 10.7717/peerj.1318  0.01
2015 Shaw PJ, Chaotheing S, Kaewprommal P, Piriyapongsa J, Wongsombat C, Suwannakitti N, Koonyosying P, Uthaipibull C, Yuthavong Y, Kamchonwongpaisan S. Plasmodium parasites mount an arrest response to dihydroartemisinin, as revealed by whole transcriptome shotgun sequencing (RNA-seq) and microarray study. Bmc Genomics. 16: 830. PMID 26490244 DOI: 10.1186/s12864-015-2040-0  0.01
2015 Koyyalamudi SR, Kuzhiumparambil U, Nath CE, Byrne JA, Fraser CJ, O'Brien TA, Earl JW, Shaw PJ. Development and Validation of a High Pressure Liquid Chromatography-UV Method for the Determination of Treosulfan and Its Epoxy Metabolites in Human Plasma and Its Application in Pharmacokinetic Studies. Journal of Chromatographic Science. PMID 26433392 DOI: 10.1093/chromsci/bmv145  0.01
2015 Rispo A, Williams ID, Shaw PJ. Source segregation and food waste prevention activities in high-density households in a deprived urban area. Waste Management (New York, N.Y.). 44: 15-27. PMID 26233881 DOI: 10.1016/j.wasman.2015.04.010  0.01
2015 Bogg TF, Shaw PJ, Cohn RJ, Wakefield CE, Hardy LL, Broderick C, Naumann F. Physical activity and screen-time of childhood haematopoietic stem cell transplant survivors. Acta Paediatrica (Oslo, Norway : 1992). 104: e455-9. PMID 26174593 DOI: 10.1111/apa.13120  0.01
2015 Dissel S, Melnattur K, Shaw PJ. Sleep, Performance, and Memory in Flies. Current Sleep Medicine Reports. 1: 47-54. PMID 26120553 DOI: 10.1007/s40675-014-0006-4  0.01
2015 Cooper-Knock J, Bury JJ, Heath PR, Wyles M, Higginbottom A, Gelsthorpe C, Highley JR, Hautbergue G, Rattray M, Kirby J, Shaw PJ. C9ORF72 GGGGCC Expanded Repeats Produce Splicing Dysregulation which Correlates with Disease Severity in Amyotrophic Lateral Sclerosis. Plos One. 10: e0127376. PMID 26016851 DOI: 10.1371/journal.pone.0127376  0.01
2015 Farmer TD, Shaw PJ, Williams ID. Destined for indecision? A critical analysis of waste management practices in England from 1996 to 2013. Waste Management (New York, N.Y.). 39: 266-76. PMID 25771762 DOI: 10.1016/j.wasman.2015.02.023  0.01
2015 Little D, Valori CF, Mutsaers CA, Bennett EJ, Wyles M, Sharrack B, Shaw PJ, Gillingwater TH, Azzouz M, Ning K. PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 270-7. PMID 25369768 DOI: 10.1038/mt.2014.209  0.01
2015 Sutton R, Shaw PJ, Venn NC, Law T, Dissanayake A, Kilo T, Haber M, Norris MD, Fraser C, Alvaro F, Revesz T, Trahair TN, Dalla-Pozza L, Marshall GM, O'Brien TA. Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia. British Journal of Haematology. 168: 395-404. PMID 25312094 DOI: 10.1111/bjh.13142  0.01
2015 Worthington TA, Shaw PJ, Daffern JR, Langford TEL. The effects of a thermal discharge on the macroinvertebrate community of a large British river: implications for climate change Hydrobiologia. 753: 81-95. DOI: 10.1007/s10750-015-2197-1  0.01
2014 Wongsombat C, Aroonsri A, Kamchonwongpaisan S, Morgan HP, Walkinshaw MD, Yuthavong Y, Shaw PJ. Molecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins. Molecular and Biochemical Parasitology. 198: 1-10. PMID 25447287 DOI: 10.1016/j.molbiopara.2014.10.005  0.01
2014 Shaw PJ, Nath CE, Lazarus HM. Not too little, not too much-just right! (Better ways to give high dose melphalan). Bone Marrow Transplantation. 49: 1457-65. PMID 25133893 DOI: 10.1038/bmt.2014.186  0.01
2014 Ozanne CM, Cabral C, Shaw PJ. Variation in indigenous forest resource use in central Guyana. Plos One. 9: e102952. PMID 25068801 DOI: 10.1371/journal.pone.0102952  0.01
2014 Elsworth B, Matthews K, Nie CQ, Kalanon M, Charnaud SC, Sanders PR, Chisholm SA, Counihan NA, Shaw PJ, Pino P, Chan JA, Azevedo MF, Rogerson SJ, Beeson JG, Crabb BS, et al. PTEX is an essential nexus for protein export in malaria parasites. Nature. 511: 587-91. PMID 25043043 DOI: 10.1038/nature13555  0.01
2014 Sleebs BE, Lopaticki S, Marapana DS, O'Neill MT, Rajasekaran P, Gazdik M, Günther S, Whitehead LW, Lowes KN, Barfod L, Hviid L, Shaw PJ, Hodder AN, Smith BJ, Cowman AF, et al. Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites. Plos Biology. 12: e1001897. PMID 24983235 DOI: 10.1371/journal.pbio.1001897  0.01
2014 Diekstra FP, Van Deerlin VM, van Swieten JC, Al-Chalabi A, Ludolph AC, Weishaupt JH, Hardiman O, Landers JE, Brown RH, van Es MA, Pasterkamp RJ, Koppers M, Andersen PM, Estrada K, Rivadeneira F, ... ... Shaw PJ, et al. C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. Annals of Neurology. 76: 120-33. PMID 24931836 DOI: 10.1002/ana.24198  0.01
2014 Karski EE, Dvorak CC, Leung W, Miller W, Shaw PJ, Qayed M, Katsanis E, Feusner JH. Treatment of hepatoblastoma with high-dose chemotherapy and stem cell rescue: the pediatric blood and marrow transplant consortium experience and review of the literature. Journal of Pediatric Hematology/Oncology. 36: 362-8. PMID 24577552 DOI: 10.1097/MPH.0000000000000130  0.01
2014 Alçada J, Taylor MN, Shaw PJ, Janes SM, Navani N, Miller RF. High prevalence of malignancy in HIV-positive patients with mediastinal lymphadenopathy: a study in the era of antiretroviral therapy. Respirology (Carlton, Vic.). 19: 339-45. PMID 24471994 DOI: 10.1111/resp.12241  0.01
2014 Güngör T, Teira P, Slatter M, Stussi G, Stepensky P, Moshous D, Vermont C, Ahmad I, Shaw PJ, Telles da Cunha JM, Schlegel PG, Hough R, Fasth A, Kentouche K, Gruhn B, et al. Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study. Lancet. 383: 436-48. PMID 24161820 DOI: 10.1016/S0140-6736(13)62069-3  0.01
2013 Wangkumhang P, Shaw PJ, Chaichoompu K, Ngamphiw C, Assawamakin A, Nuinoon M, Sripichai O, Svasti S, Fucharoen S, Praphanphoj V, Tongsima S. Insight into the peopling of Mainland Southeast Asia from Thai population genetic structure. Plos One. 8: e79522. PMID 24223962 DOI: 10.1371/journal.pone.0079522  0.01
2013 Aryee AM, Solomon AW, Taylor MN, Kidd IM, Shaw PJ, Miller RF. Clinical, radiological and laboratory features of human metapneumovirus lower respiratory tract infection in HIV-positive patients: a case series. Aids (London, England). 27: 2317-9. PMID 24157909 DOI: 10.1097/01.aids.0000432461.21723.36  0.01
2013 Assawamakin A, Prueksaaroon S, Kulawonganunchai S, Shaw PJ, Varavithya V, Ruangrajitpakorn T, Tongsima S. Biomarker selection and classification of "-omics" data using a two-step bayes classification framework. Biomed Research International. 2013: 148014. PMID 24106694 DOI: 10.1155/2013/148014  0.01
2013 Savic RM, Cowan MJ, Dvorak CC, Pai SY, Pereira L, Bartelink IH, Boelens JJ, Bredius RG, Wynn RF, Cuvelier GD, Shaw PJ, Slatter MA, Long-Boyle J. Effect of weight and maturation on busulfan clearance in infants and small children undergoing hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 1608-14. PMID 24029650 DOI: 10.1016/j.bbmt.2013.08.014  0.01
2013 Prommana P, Uthaipibull C, Wongsombat C, Kamchonwongpaisan S, Yuthavong Y, Knuepfer E, Holder AA, Shaw PJ. Inducible knockdown of Plasmodium gene expression using the glmS ribozyme. Plos One. 8: e73783. PMID 24023691 DOI: 10.1371/journal.pone.0073783  0.01
2013 Mitchell R, Nivison-Smith I, Anazodo A, Tiedemann K, Shaw PJ, Teague L, Fraser CJ, Carter TL, Tapp H, Alvaro F, O'Brien TA. Outcomes of haematopoietic stem cell transplantation for inherited metabolic disorders: a report from the Australian and New Zealand Children's Haematology Oncology Group and the Australasian Bone Marrow Transplant Recipient Registry. Pediatric Transplantation. 17: 582-8. PMID 23802616 DOI: 10.1111/petr.12109  0.01
2013 Groen EJ, Fumoto K, Blokhuis AM, Engelen-Lee J, Zhou Y, van den Heuvel DM, Koppers M, van Diggelen F, van Heest J, Demmers JA, Kirby J, Shaw PJ, Aronica E, Spliet WG, Veldink JH, et al. ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN. Human Molecular Genetics. 22: 3690-704. PMID 23681068 DOI: 10.1093/hmg/ddt222  0.01
2013 Morrison KE, Dhariwal S, Hornabrook R, Savage L, Burn DJ, Khoo TK, Kelly J, Murphy CL, Al-Chalabi A, Dougherty A, Leigh PN, Wijesekera L, Thornhill M, Ellis CM, ... ... Shaw PJ, et al. Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial. The Lancet. Neurology. 12: 339-45. PMID 23453347 DOI: 10.1016/S1474-4422(13)70037-1  0.01
2013 Blyth E, Clancy L, Simms R, Ma CK, Burgess J, Deo S, Byth K, Dubosq MC, Shaw PJ, Micklethwaite KP, Gottlieb DJ. Donor-derived CMV-specific T cells reduce the requirement for CMV-directed pharmacotherapy after allogeneic stem cell transplantation. Blood. 121: 3745-58. PMID 23435462 DOI: 10.1182/blood-2012-08-448977  0.01
2013 Hale GA, Arora M, Ahn KW, He W, Camitta B, Bishop MR, Bitan M, Cairo MS, Chan K, Childs RW, Copelan E, Davies SM, Perez MA, Doyle JJ, Gale RP, ... ... Shaw PJ, et al. Allogeneic hematopoietic cell transplantation for neuroblastoma: the CIBMTR experience. Bone Marrow Transplantation. 48: 1056-64. PMID 23419433 DOI: 10.1038/bmt.2012.284  0.01
2013 Clancy LE, Blyth E, Simms RM, Micklethwaite KP, Ma CK, Burgess JS, Antonenas V, Shaw PJ, Gottlieb DJ. Cytomegalovirus-specific cytotoxic T lymphocytes can be efficiently expanded from granulocyte colony-stimulating factor-mobilized hemopoietic progenitor cell products ex vivo and safely transferred to stem cell transplantation recipients to facilitate immune reconstitution. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 725-34. PMID 23380344 DOI: 10.1016/j.bbmt.2013.01.021  0.01
2013 Maxwell SL, Culligan BK, Shaw PJ. Rapid determination of radiostrontium in large soil samples Journal of Radioanalytical and Nuclear Chemistry. 295: 965-971. DOI: 10.1007/s10967-012-1863-2  0.01
2012 Sillence D, Waters K, Donaldson S, Shaw PJ, Ellaway C. Combined Enzyme Replacement Therapy and Hematopoietic Stem Cell Transplantation in Mucopolysacharidosis Type VI. Jimd Reports. 2: 103-6. PMID 23430861 DOI: 10.1007/8904_2011_56  0.01
2012 Piriyapongsa J, Ngamphiw C, Intarapanich A, Kulawonganunchai S, Assawamakin A, Bootchai C, Shaw PJ, Tongsima S. iLOCi: a SNP interaction prioritization technique for detecting epistasis in genome-wide association studies. Bmc Genomics. 13: S2. PMID 23281813 DOI: 10.1186/1471-2164-13-S7-S2  0.01
2012 Richards DM, Greer E, Martin AC, Moore G, Shaw PJ, Howard M. Quantitative dynamics of telomere bouquet formation. Plos Computational Biology. 8: e1002812. PMID 23236272 DOI: 10.1371/journal.pcbi.1002812  0.01
2012 Matthes-Martin S, Feuchtinger T, Shaw PJ, Engelhard D, Hirsch HH, Cordonnier C, Ljungman P. European guidelines for diagnosis and treatment of adenovirus infection in leukemia and stem cell transplantation: summary of ECIL-4 (2011). Transplant Infectious Disease : An Official Journal of the Transplantation Society. 14: 555-63. PMID 23146063 DOI: 10.1111/tid.12022  0.01
2012 Seale H, Trung L, Mackie FE, Kennedy SE, Boros C, Marshall H, Tidswell J, Shaw PJ, Montgomery K, MacIntyre CR. A qualitative study investigating knowledge and attitudes regarding human papillomavirus (HPV) and the HPV vaccine among parents of immunosuppressed children. Vaccine. 30: 7027-31. PMID 23059356 DOI: 10.1016/j.vaccine.2012.09.066  0.01
2012 Wen R, Moore G, Shaw PJ. Centromeres cluster de novo at the beginning of meiosis in Brachypodium distachyon. Plos One. 7: e44681. PMID 22970287 DOI: 10.1371/journal.pone.0044681  0.01
2012 Bartelink IH, Boelens JJ, Bredius RG, Egberts AC, Wang C, Bierings MB, Shaw PJ, Nath CE, Hempel G, Zwaveling J, Danhof M, Knibbe CA. Body weight-dependent pharmacokinetics of busulfan in paediatric haematopoietic stem cell transplantation patients: towards individualized dosing. Clinical Pharmacokinetics. 51: 331-45. PMID 22455797 DOI: 10.2165/11598180-000000000-00000  0.01
2012 Ahmed AA, Taylor MN, Shaw PJ. Percutaneous Biopsy Procedures: Techniques and Indications Clinical Respiratory Medicine: Fourth Edition. 180-192. DOI: 10.1016/B978-1-4557-0792-8.00013-1  0.01
2012 Maxwell SL, Culligan BK, Kelsey-Wall A, Shaw PJ. Rapid determination of actinides in emergency food samples Journal of Radioanalytical and Nuclear Chemistry. 292: 339-347. DOI: 10.1007/s10967-011-1411-5  0.01
2011 Park JR, Scott JR, Stewart CF, London WB, Naranjo A, Santana VM, Shaw PJ, Cohn SL, Matthay KK. Pilot induction regimen incorporating pharmacokinetically guided topotecan for treatment of newly diagnosed high-risk neuroblastoma: a Children's Oncology Group study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 4351-7. PMID 22010014 DOI: 10.1200/JCO.2010.34.3293  0.01
2011 Kritsiriwuthinan K, Chaotheing S, Shaw PJ, Wongsombat C, Chavalitshewinkoon-Petmitr P, Kamchonwongpaisan S. Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine. Malaria Journal. 10: 242. PMID 21849091 DOI: 10.1186/1475-2875-10-242  0.01
2011 Tongsima S, Assawamakin A, Piriyapongsa J, Shaw PJ. Comparative view of in silico DNA sequencing analysis tools. Methods in Molecular Biology (Clifton, N.J.). 760: 207-21. PMID 21779999 DOI: 10.1007/978-1-61779-176-5_13  0.01
2011 Emerson BC, Cicconardi F, Fanciulli PP, Shaw PJ. Phylogeny, phylogeography, phylobetadiversity and the molecular analysis of biological communities. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2391-402. PMID 21768154 DOI: 10.1098/rstb.2011.0057  0.01
2011 Maxwell SL, Culligan BK, Kelsey-Wall A, Shaw PJ. Rapid radiochemical method for determination of actinides in emergency concrete and brick samples. Analytica Chimica Acta. 701: 112-8. PMID 21763816 DOI: 10.1016/j.aca.2011.06.011  0.01
2011 Ngamphiw C, Assawamakin A, Xu S, Shaw PJ, Yang JO, Ghang H, Bhak J, Liu E, Tongsima S. PanSNPdb: the Pan-Asian SNP genotyping database. Plos One. 6: e21451. PMID 21731755 DOI: 10.1371/journal.pone.0021451  0.01
2011 Limpiti T, Intarapanich A, Assawamakin A, Shaw PJ, Wangkumhang P, Piriyapongsa J, Ngamphiw C, Tongsima S. Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and structure. Bmc Bioinformatics. 12: 255. PMID 21699684 DOI: 10.1186/1471-2105-12-255  0.01
2011 Shaw PJ, Shackleton K. Carnivory in the teasel Dipsacus fullonum--the effect of experimental feeding on growth and seed set. Plos One. 6: e17935. PMID 21445274 DOI: 10.1371/journal.pone.0017935  0.01
2011 Williams CD, Antoine DJ, Shaw PJ, Benson C, Farhood A, Williams DP, Kanneganti TD, Park BK, Jaeschke H. Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury. Toxicology and Applied Pharmacology. 252: 289-97. PMID 21396389 DOI: 10.1016/j.taap.2011.03.001  0.01
2011 Barber SC, Wood-Allum CA, Sargsyan SA, Walsh T, Cox LE, Monk PN, Shaw PJ. Contrasting effects of cerebrospinal fluid from motor neuron disease patients on the survival of primary motor neurons cultured with or without glia. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 12: 257-63. PMID 21366496 DOI: 10.3109/17482968.2011.560672  0.01
2011 Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo SW, Valori CF, Cox L, Sharrack B, Wharton SB, Ince PG, Shaw PJ, Azzouz M. Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 134: 506-17. PMID 21228060 DOI: 10.1093/brain/awq345  0.01
2011 Shaw PJ, McDermott MF, Kanneganti TD. Inflammasomes and autoimmunity. Trends in Molecular Medicine. 17: 57-64. PMID 21163704 DOI: 10.1016/j.molmed.2010.11.001  0.01
2011 Ladenstein R, Pötschger U, Siabalis D, Garaventa A, Bergeron C, Lewis IJ, Stein J, Kohler J, Shaw PJ, Holter W, Pistoia V, Michon J. Dose finding study for the use of subcutaneous recombinant interleukin-2 to augment natural killer cell numbers in an outpatient setting for stage 4 neuroblastoma after megatherapy and autologous stem-cell reinfusion. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 441-8. PMID 21149662 DOI: 10.1200/JCO.2009.23.5465  0.01
2011 Chanama M, Chanama S, Shaw PJ, Chitnumsub P, Leartsakulpanich U, Yuthavong Y. Formation of catalytically active cross-species heterodimers of thymidylate synthase from Plasmodium falciparum and Plasmodium vivax. Molecular Biology Reports. 38: 1029-37. PMID 20577818 DOI: 10.1007/s11033-010-0199-7  0.01
2011 Dixon MJ, Shaw PJ. Watercress and water quality: The effect of phenethyl isothiocyanate on the mating behaviour of Gammarus pulex International Journal of Zoology. DOI: 10.1155/2011/328749  0.01
2011 Shaw PJ, McKeown PC. The structure of rDNA chromatin Protein Reviews. 15: 43-55. DOI: 10.1007/978-1-4614-0514-6-3  0.01
2010 Shaw PJ. Mapping chromatin conformation. F1000 Biology Reports. 2. PMID 20948815 DOI: 10.3410/B2-18  0.01
2010 Zeng L, Blair EY, Nath CE, Shaw PJ, Earl JW, Stephen K, Montgomery K, Coakley JC, Hodson E, Stormon M, McLachlan AJ. Population pharmacokinetics of mycophenolic acid in children and young people undergoing blood or marrow and solid organ transplantation. British Journal of Clinical Pharmacology. 70: 567-79. PMID 20840448 DOI: 10.1111/j.1365-2125.2010.03734.x  0.01
2010 Wood-Allum C, Shaw PJ. Motor neurone disease: a practical update on diagnosis and management. Clinical Medicine (London, England). 10: 252-8. PMID 20726457  0.01
2010 Shaw PJ, Kan F, Woo Ahn K, Spellman SR, Aljurf M, Ayas M, Burke M, Cairo MS, Chen AR, Davies SM, Frangoul H, Gajewski J, Gale RP, Godder K, Hale GA, et al. Outcomes of pediatric bone marrow transplantation for leukemia and myelodysplasia using matched sibling, mismatched related, or matched unrelated donors. Blood. 116: 4007-15. PMID 20671124 DOI: 10.1182/blood-2010-01-261958  0.01
2010 Besson H, Harwood CA, Ekelund U, Finucane FM, McDermott CJ, Shaw PJ, Wareham NJ. Validation of the historical adulthood physical activity questionnaire (HAPAQ) against objective measurements of physical activity. The International Journal of Behavioral Nutrition and Physical Activity. 7: 54. PMID 20576086 DOI: 10.1186/1479-5868-7-54  0.01
2010 Nath CE, Shaw PJ, Trotman J, Zeng L, Duffull SB, Hegarty G, McLachlan AJ, Gurney H, Kerridge I, Kwan YL, Presgrave P, Tiley C, Joshua D, Earl J. Population pharmacokinetics of melphalan in patients with multiple myeloma undergoing high dose therapy. British Journal of Clinical Pharmacology. 69: 484-97. PMID 20573084 DOI: 10.1111/j.1365-2125.2010.03638.x  0.01
2010 Chavada G, El-Nayal A, Lee F, Webber SJ, McAlindon M, Walsh T, Hollinger H, McDermott CJ, Shaw PJ. Evaluation of two different methods for per-oral gastrostomy tube placement in patients with motor neuron disease (MND): PIG versus PEG procedures. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 531-6. PMID 20553092 DOI: 10.3109/17482968.2010.494306  0.01
2010 Valori CF, Ning K, Wyles M, Mead RJ, Grierson AJ, Shaw PJ, Azzouz M. Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy. Science Translational Medicine. 2: 35ra42. PMID 20538619 DOI: 10.1126/scitranslmed.3000830  0.01
2010 Douglass CP, Kandler RH, Shaw PJ, McDermott CJ. An evaluation of neurophysiological criteria used in the diagnosis of motor neuron disease. Journal of Neurology, Neurosurgery, and Psychiatry. 81: 646-9. PMID 20522872 DOI: 10.1136/jnnp.2009.197434  0.01
2010 Shaw PJ, Lamkanfi M, Kanneganti TD. NOD-like receptor (NLR) signaling beyond the inflammasome. European Journal of Immunology. 40: 624-7. PMID 20201016 DOI: 10.1002/eji.200940211  0.01
2010 Hale KA, Shaw PJ, Dalla-Pozza L, MacIntyre CR, Isaacs D, Sorrell TC. Epidemiology of paediatric invasive fungal infections and a case-control study of risk factors in acute leukaemia or post stem cell transplant. British Journal of Haematology. 149: 263-72. PMID 20096013 DOI: 10.1111/j.1365-2141.2009.08072.x  0.01
2010 Kim SH, Spensley M, Choi SK, Calixto CP, Pendle AF, Koroleva O, Shaw PJ, Brown JW. Plant U13 orthologues and orphan snoRNAs identified by RNomics of RNA from Arabidopsis nucleoli. Nucleic Acids Research. 38: 3054-67. PMID 20081206 DOI: 10.1093/nar/gkp1241  0.01
2010 Barber SC, Shaw PJ. Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radical Biology & Medicine. 48: 629-41. PMID 19969067 DOI: 10.1016/j.freeradbiomed.2009.11.018  0.01
2010 Suryani S, Fulcher DA, Santner-Nanan B, Nanan R, Wong M, Shaw PJ, Gibson J, Williams A, Tangye SG. Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells. Blood. 115: 519-29. PMID 19965666 DOI: 10.1182/blood-2009-07-234799  0.01
2010 Dvorácková M, Rossignol P, Shaw PJ, Koroleva OA, Doonan JH, Fajkus J. AtTRB1, a telomeric DNA-binding protein from Arabidopsis, is concentrated in the nucleolus and shows highly dynamic association with chromatin. The Plant Journal : For Cell and Molecular Biology. 61: 637-49. PMID 19947985 DOI: 10.1111/j.1365-313X.2009.04094.x  0.01
2010 Bawankar P, Shaw PJ, Sardana R, Babar PH, Patankar S. 5' and 3' end modifications of spliceosomal RNAs in Plasmodium falciparum. Molecular Biology Reports. 37: 2125-33. PMID 19669595 DOI: 10.1007/s11033-009-9682-4  0.01
2009 Koroleva OA, Brown JW, Shaw PJ. Localization of eIF4A-III in the nucleolus and splicing speckles is an indicator of plant stress. Plant Signaling & Behavior. 4: 1148-51. PMID 20514231  0.01
2009 Jongkon N, Mokmak W, Chuakheaw D, Shaw PJ, Tongsima S, Sangma C. Prediction of avian influenza A binding preference to human receptor using conformational analysis of receptor bound to hemagglutinin. Bmc Genomics. 10: S24. PMID 19958488 DOI: 10.1186/1471-2164-10-S3-S24  0.01
2009 Intarapanich A, Shaw PJ, Assawamakin A, Wangkumhang P, Ngamphiw C, Chaichoompu K, Piriyapongsa J, Tongsima S. Iterative pruning PCA improves resolution of highly structured populations. Bmc Bioinformatics. 10: 382. PMID 19930644 DOI: 10.1186/1471-2105-10-382  0.01
2009 Sargsyan SA, Blackburn DJ, Barber SC, Monk PN, Shaw PJ. Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1. Neuroreport. 20: 1450-5. PMID 19752764 DOI: 10.1097/WNR.0b013e328331e8fa  0.01
2009 Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proceedings of the National Academy of Sciences of the United States of America. 106: 12025-30. PMID 19587242 DOI: 10.1073/pnas.0905922106  0.01
2009 Pulsipher MA, Boucher KM, Wall D, Frangoul H, Duval M, Goyal RK, Shaw PJ, Haight AE, Grimley M, Grupp SA, Kletzel M, Kadota R. Reduced-intensity allogeneic transplantation in pediatric patients ineligible for myeloablative therapy: results of the Pediatric Blood and Marrow Transplant Consortium Study ONC0313. Blood. 114: 1429-36. PMID 19528536 DOI: 10.1182/blood-2009-01-196303  0.01
2009 Koroleva OA, Calder G, Pendle AF, Kim SH, Lewandowska D, Simpson CG, Jones IM, Brown JW, Shaw PJ. Dynamic behavior of Arabidopsis eIF4A-III, putative core protein of exon junction complex: fast relocation to nucleolus and splicing speckles under hypoxia. The Plant Cell. 21: 1592-606. PMID 19435936 DOI: 10.1105/tpc.108.060434  0.01
2009 Zeng L, Nath CE, Blair EY, Shaw PJ, Stephen K, Earl JW, Coakley JC, McLachlan AJ. Population pharmacokinetics of acyclovir in children and young people with malignancy after administration of intravenous acyclovir or oral valacyclovir. Antimicrobial Agents and Chemotherapy. 53: 2918-27. PMID 19414579 DOI: 10.1128/AAC.01138-08  0.01
2009 Bhadri VA, Lee-Horn L, Shaw PJ. Safety and tolerability of cidofovir in high-risk pediatric patients. Transplant Infectious Disease : An Official Journal of the Transplantation Society. 11: 373-9. PMID 19392729 DOI: 10.1111/j.1399-3062.2009.00391.x  0.01
2009 Blackburn D, Sargsyan S, Monk PN, Shaw PJ. Astrocyte function and role in motor neuron disease: a future therapeutic target? Glia. 57: 1251-64. PMID 19373940 DOI: 10.1002/glia.20848  0.01
2009 Ferraiuolo L, De Bono JP, Heath PR, Holden H, Kasher P, Channon KM, Kirby J, Shaw PJ. Transcriptional response of the neuromuscular system to exercise training and potential implications for ALS. Journal of Neurochemistry. 109: 1714-24. PMID 19344372 DOI: 10.1111/j.1471-4159.2009.06080.x  0.01
2009 Harwood CA, McDermott CJ, Shaw PJ. Physical activity as an exogenous risk factor in motor neuron disease (MND): a review of the evidence. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 10: 191-204. PMID 19263258 DOI: 10.1080/17482960802549739  0.01
2009 Moore AS, Shaw PJ, Hallahan AR, Carter TL, Kilo T, Nivison-Smith I, O'Brien TA, Tapp H, Teague L, Wilson SR, Tiedemann K. Haemopoietic stem cell transplantation for children in Australia and New Zealand, 1998-2006: a report on behalf of the Australasian Bone Marrow Transplant Recipient Registry and the Australian and New Zealand Children's Haematology Oncology Group. The Medical Journal of Australia. 190: 121-5. PMID 19203307  0.01
2009 McKeown PC, Shaw PJ. Chromatin: linking structure and function in the nucleolus. Chromosoma. 118: 11-23. PMID 18925405 DOI: 10.1007/s00412-008-0184-2  0.01
2009 Zeng L, Nath CE, Shaw PJ, Earl JW, McLachlan AJ. HPLC-UV assay for monitoring total and unbound mycophenolic acid concentrations in children. Biomedical Chromatography : Bmc. 23: 92-100. PMID 18823076 DOI: 10.1002/bmc.1088  0.01
2009 Petterson TE, Gabriel M, Tiedemann K, Teague L, Shaw PJ, Baker D, Bolton-Jones R, Tapp H, Oswald C, Vowels MR, O'Brien TA. Outcome following unrelated cord blood transplant in 136 patients with malignant and non-malignant diseases: a report from the Australian and New Zealand children's haematology and oncology group. Bone Marrow Transplantation. 43: 207-15. PMID 18806837 DOI: 10.1038/bmt.2008.314  0.01
2009 Samuel GN, Strong KA, Kerridge I, Jordens CF, Ankeny RA, Shaw PJ. Establishing the role of pre-implantation genetic diagnosis with human leucocyte antigen typing: what place do "saviour siblings" have in paediatric transplantation? Archives of Disease in Childhood. 94: 317-20. PMID 18684746 DOI: 10.1136/adc.2008.138529  0.01
2008 McKeown P, Pendle AF, Shaw PJ. Preparation of Arabidopsis nuclei and nucleoli. Methods in Molecular Biology (Clifton, N.J.). 463: 67-75. PMID 18951161 DOI: 10.1007/978-1-59745-406-3_5  0.01
2008 Lemke S, Stauber M, Shaw PJ, Rafiqi AM, Prell A, Schmidt-Ott U. Bicoid occurrence and Bicoid-dependent hunchback regulation in lower cyclorrhaphan flies. Evolution & Development. 10: 413-20. PMID 18638318 DOI: 10.1111/j.1525-142X.2008.00252.x  0.01
2008 Brown JW, Shaw PJ. The role of the plant nucleolus in pre-mRNA processing. Current Topics in Microbiology and Immunology. 326: 291-311. PMID 18630759  0.01
2008 Hewamadduma CA, Kirby J, Kershaw C, Martindale J, Dalton A, McDermott CJ, Shaw PJ. HSP60 is a rare cause of hereditary spastic paraparesis, but may act as a genetic modifier. Neurology. 70: 1717-8. PMID 18458233 DOI: 10.1212/01.wnl.0000311395.31081.70  0.01
2008 Khan NI, Cisterne A, Devidas M, Shuster J, Hunger SP, Shaw PJ, Bradstock KF, Bendall LJ. Expression of CD44, but not CD44v6, predicts relapse in children with B cell progenitor acute lymphoblastic leukemia lacking adverse or favorable genetics. Leukemia & Lymphoma. 49: 710-8. PMID 18398738 DOI: 10.1080/10428190701861660  0.01
2008 Ozkaynak MF, Sahdev I, Gross TG, Levine JE, Cheerva AC, Richards MK, Rozans MK, Shaw PJ, Kadota RP. A pilot study of addition of amifostine to melphalan, carboplatin, etoposide, and cyclophosphamide with autologous hematopoietic stem cell transplantation in pediatric solid tumors-A pediatric blood and marrow transplant consortium study. Journal of Pediatric Hematology/Oncology. 30: 204-9. PMID 18376282 DOI: 10.1097/MPH.0b013e318162bd0c  0.01
2008 McDermott CJ, Shaw PJ. Diagnosis and management of motor neurone disease. Bmj (Clinical Research Ed.). 336: 658-62. PMID 18356234 DOI: 10.1136/bmj.39493.511759.BE  0.01
2008 Zeng L, Nath CE, Shaw PJ, Earl JW, McLachlan AJ. HPLC-fluorescence assay for acyclovir in children. Biomedical Chromatography : Bmc. 22: 879-87. PMID 18348336 DOI: 10.1002/bmc.1006  0.01
2008 Derbyshire P, Drea S, Shaw PJ, Doonan JH, Dolan L. Proximal-distal patterns of transcription factor gene expression during Arabidopsis root development. Journal of Experimental Botany. 59: 235-45. PMID 18263631 DOI: 10.1093/jxb/erm301  0.01
2008 Alexander SI, Smith N, Hu M, Verran D, Shun A, Dorney S, Smith A, Webster B, Shaw PJ, Lammi A, Stormon MO. Chimerism and tolerance in a recipient of a deceased-donor liver transplant. The New England Journal of Medicine. 358: 369-74. PMID 18216357 DOI: 10.1056/NEJMoa0707255  0.01
2008 Shaw PJ, Maynard SJ. The potential of financial incentives to enhance householders' kerbside recycling behaviour. Waste Management (New York, N.Y.). 28: 1732-41. PMID 17904348 DOI: 10.1016/j.wasman.2007.08.008  0.01
2007 McDermott CJ, Shaw PJ. Chapter 17 Hereditary spastic paraparesis. Handbook of Clinical Neurology. 82: 327-52. PMID 18808902 DOI: 10.1016/S0072-9752(07)80020-0  0.01
2007 Barber SC, Shaw PJ. Chapter 4 Molecular mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis. Handbook of Clinical Neurology. 82: 57-87. PMID 18808889 DOI: 10.1016/S0072-9752(07)80007-8  0.01
2007 Eisen AA, Shaw PJ. Preface. Handbook of Clinical Neurology. 82: ix. PMID 18808884 DOI: 10.1016/S0072-9752(07)80002-9  0.01
2007 Nath CE, Shaw PJ. Busulphan in blood and marrow transplantation: dose, route, frequency and role of therapeutic drug monitoring. Current Clinical Pharmacology. 2: 75-91. PMID 18690856  0.01
2007 Dewil M, Lambrechts D, Sciot R, Shaw PJ, Ince PG, Robberecht W, Van den Bosch L. Vascular endothelial growth factor counteracts the loss of phospho-Akt preceding motor neurone degeneration in amyotrophic lateral sclerosis. Neuropathology and Applied Neurobiology. 33: 499-509. PMID 17854437 DOI: 10.1111/j.1365-2990.2007.00850.x  0.01
2007 Christou YA, Moore HD, Shaw PJ, Monk PN. Embryonic stem cells and prospects for their use in regenerative medicine approaches to motor neurone disease. Neuropathology and Applied Neurobiology. 33: 485-98. PMID 17854436 DOI: 10.1111/j.1365-2990.2007.00883.x  0.01
2007 Ferraiuolo L, Heath PR, Holden H, Kasher P, Kirby J, Shaw PJ. Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9201-19. PMID 17715356 DOI: 10.1523/JNEUROSCI.1470-07.2007  0.01
2007 Shaw PJ, Ponmee N, Karoonuthaisiri N, Kamchonwongpaisan S, Yuthavong Y. Characterization of human malaria parasite Plasmodium falciparum eIF4E homologue and mRNA 5' cap status. Molecular and Biochemical Parasitology. 155: 146-55. PMID 17692399 DOI: 10.1016/j.molbiopara.2007.07.003  0.01
2007 Kirby J, Heath PR, Shaw PJ, Hamdy FC. Gene expression assays. Advances in Clinical Chemistry. 44: 247-92. PMID 17682345  0.01
2007 Nath CE, Shaw PJ, Trotman J, Zeng L. Pharmacokinetics of melphalan in myeloma patients undergoing an autograft. Bone Marrow Transplantation. 40: 707-8. PMID 17680022 DOI: 10.1038/sj.bmt.1705797  0.01
2007 Howman-Giles R, Shaw PJ, Uren RF, Chung DK. Neuroblastoma and other neuroendocrine tumors. Seminars in Nuclear Medicine. 37: 286-302. PMID 17544628 DOI: 10.1053/j.semnuclmed.2007.02.009  0.01
2007 Brockington A, Wokke B, Nixon H, Hartley J, Shaw PJ. Screening of the transcriptional regulatory regions of vascular endothelial growth factor receptor 2 (VEGFR2) in amyotrophic lateral sclerosis. Bmc Medical Genetics. 8: 23. PMID 17456229 DOI: 10.1186/1471-2350-8-23  0.01
2007 Beetz C, Zuchner S, Ashley-Koch A, Auer-Grumbach M, Byrne P, Chinnery PF, Hutchinson M, McDermott CJ, Meijer IA, Nygren AO, Pericak-Vance M, Pyle A, Rouleau GA, Schickel J, Shaw PJ, et al. Linkage to a known gene but no mutation identified: comprehensive reanalysis of SPG4 HSP pedigrees reveals large deletions as the sole cause. Human Mutation. 28: 739-40. PMID 17345589 DOI: 10.1002/humu.20508  0.01
2007 Nath CE, Shaw PJ, Montgomery K, Earl JW. Population pharmacokinetics of melphalan in paediatric blood or marrow transplant recipients. British Journal of Clinical Pharmacology. 64: 151-64. PMID 17324241 DOI: 10.1111/j.1365-2125.2007.02862.x  0.01
2007 Nath CE, McLachlan AJ, Shaw PJ, Coakley JC, Earl JW. Amphotericin B dose optimization in children with malignant diseases. Chemotherapy. 53: 142-7. PMID 17310120 DOI: 10.1159/000100013  0.01
2007 Baker DE, Harrison NJ, Maltby E, Smith K, Moore HD, Shaw PJ, Heath PR, Holden H, Andrews PW. Adaptation to culture of human embryonic stem cells and oncogenesis in vivo. Nature Biotechnology. 25: 207-15. PMID 17287758 DOI: 10.1038/nbt1285  0.01
2007 Hong Y, Shaw PJ, Tattam BN, Nath CE, Earl JW, Stephen KR, McLachlan AJ. Plasma protein distribution and its impact on pharmacokinetics of liposomal amphotericin B in paediatric patients with malignant diseases. European Journal of Clinical Pharmacology. 63: 165-72. PMID 17180621 DOI: 10.1007/s00228-006-0240-x  0.01
2007 Shaw PJ, Lyas JK, Maynard SJ, van Vugt M. On the relationship between set-out rates and participation ratios as a tool for enhancement of kerbside household waste recycling. Journal of Environmental Management. 83: 34-43. PMID 16631302 DOI: 10.1016/j.jenvman.2006.01.012  0.01
2006 Raska I, Shaw PJ, Cmarko D. New insights into nucleolar architecture and activity. International Review of Cytology. 255: 177-235. PMID 17178467 DOI: 10.1016/S0074-7696(06)55004-1  0.01
2006 Selvarajah D, Wilkinson ID, Emery CJ, Harris ND, Shaw PJ, Witte DR, Griffiths PD, Tesfaye S. Early involvement of the spinal cord in diabetic peripheral neuropathy. Diabetes Care. 29: 2664-9. PMID 17130202 DOI: 10.2337/dc06-0650  0.01
2006 Bateman CM, Kesson AM, Shaw PJ. Pancreatitis and adenoviral infection in children after blood and marrow transplantation. Bone Marrow Transplantation. 38: 807-11. PMID 17057728 DOI: 10.1038/sj.bmt.1705526  0.01
2006 Barber SC, Mead RJ, Shaw PJ. Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target. Biochimica Et Biophysica Acta. 1762: 1051-67. PMID 16713195 DOI: 10.1016/j.bbadis.2006.03.008  0.01
2006 Wood-Allum CA, Barber SC, Kirby J, Heath P, Holden H, Mead R, Higginbottom A, Allen S, Beaujeux T, Alexson SE, Ince PG, Shaw PJ. Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen. Brain : a Journal of Neurology. 129: 1693-709. PMID 16702190 DOI: 10.1093/brain/awl118  0.01
2006 Raska I, Shaw PJ, Cmarko D. Structure and function of the nucleolus in the spotlight. Current Opinion in Cell Biology. 18: 325-34. PMID 16687244 DOI: 10.1016/  0.01
2006 Sastry J, Kakakios A, Tugwell H, Shaw PJ. Allogeneic bone marrow transplantation with reduced intensity conditioning for chronic granulomatous disease complicated by invasive Aspergillus infection. Pediatric Blood & Cancer. 47: 327-9. PMID 16628555 DOI: 10.1002/pbc.20865  0.01
2006 Miller RF, Shahmanesh M, Talbot MD, Wiselka MJ, Shaw PJ, Bacon C, Robertson CM. Progressive symptoms and signs following institution of highly active antiretroviral therapy and subsequent antituberculosis therapy: immune reconstitution syndrome or infection? Sexually Transmitted Infections. 82: 111-6. PMID 16581733 DOI: 10.1136/sti.2005.019323  0.01
2006 Hong Y, Shaw PJ, Nath CE, Yadav SP, Stephen KR, Earl JW, McLachlan AJ. Population pharmacokinetics of liposomal amphotericin B in pediatric patients with malignant diseases. Antimicrobial Agents and Chemotherapy. 50: 935-42. PMID 16495254 DOI: 10.1128/AAC.50.3.935-942.2006  0.01
2006 Gandhi MK, Lambley E, Burrows J, Dua U, Elliott S, Shaw PJ, Prince HM, Wolf M, Clarke K, Underhill C, Mills T, Mollee P, Gill D, Marlton P, Seymour JF, et al. Plasma Epstein-Barr virus (EBV) DNA is a biomarker for EBV-positive Hodgkin's lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 460-4. PMID 16428487 DOI: 10.1158/1078-0432.CCR-05-2008  0.01
2006 Cuss AK, Avery DT, Cannons JL, Yu LJ, Nichols KE, Shaw PJ, Tangye SG. Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity. Journal of Immunology (Baltimore, Md. : 1950). 176: 1506-16. PMID 16424179  0.01
2006 Brockington A, Wharton SB, Fernando M, Gelsthorpe CH, Baxter L, Ince PG, Lewis CE, Shaw PJ. Expression of vascular endothelial growth factor and its receptors in the central nervous system in amyotrophic lateral sclerosis. Journal of Neuropathology and Experimental Neurology. 65: 26-36. PMID 16410746  0.01
2006 Wratten NS, McGregor AP, Shaw PJ, Dover GA. Evolutionary and functional analysis of the tailless enhancer in Musca domestica and Drosophila melanogaster. Evolution & Development. 8: 6-15. PMID 16409378 DOI: 10.1111/j.1525-142X.2006.05070.x  0.01
2006 Borthwick GM, Taylor RW, Walls TJ, Tonska K, Taylor GA, Shaw PJ, Ince PG, Turnbull DM. Motor neuron disease in a patient with a mitochondrial tRNAIle mutation. Annals of Neurology. 59: 570-4. PMID 16358336 DOI: 10.1002/ana.20758  0.01
2005 Miller RF, Symeonidou C, Shaw PJ. Pneumonia complicating Shigella sonnei dysentery in an HIV-infected adult male. International Journal of Std & Aids. 16: 763-5. PMID 16303074 DOI: 10.1258/095646205774763243  0.01
2005 Sathasivam S, Grierson AJ, Shaw PJ. Characterization of the caspase cascade in a cell culture model of SOD1-related familial amyotrophic lateral sclerosis: expression, activation and therapeutic effects of inhibition. Neuropathology and Applied Neurobiology. 31: 467-85. PMID 16150118 DOI: 10.1111/j.1365-2990.2005.00658.x  0.01
2005 Miller RF, Dave SS, Tang JW, Shaw PJ, Jäger HR, Wilkins EG. Progressive neuropsychiatric problems following institution of highly active antiretroviral therapy. Sexually Transmitted Infections. 81: 351-7. PMID 16061546 DOI: 10.1136/sti.2004.014027  0.01
2005 Pamphlett R, Heath PR, Holden H, Ince PG, Shaw PJ. Detection of mutations in whole genome-amplified DNA from laser-microdissected neurons. Journal of Neuroscience Methods. 147: 65-7. PMID 16054517 DOI: 10.1016/j.jneumeth.2005.03.005  0.01
2005 Sathasivam S, Shaw PJ. Apoptosis in amyotrophic lateral sclerosis--what is the evidence? The Lancet. Neurology. 4: 500-9. PMID 16033692 DOI: 10.1016/S1474-4422(05)70142-3  0.01
2005 Shaw PJ. Molecular and cellular pathways of neurodegeneration in motor neurone disease. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 1046-57. PMID 16024877 DOI: 10.1136/jnnp.2004.048652  0.01
2005 Kirby J, Halligan E, Baptista MJ, Allen S, Heath PR, Holden H, Barber SC, Loynes CA, Wood-Allum CA, Lunec J, Shaw PJ. Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS. Brain : a Journal of Neurology. 128: 1686-706. PMID 15872021 DOI: 10.1093/brain/awh503  0.01
2005 Sargsyan SA, Monk PN, Shaw PJ. Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis. Glia. 51: 241-53. PMID 15846792 DOI: 10.1002/glia.20210  0.01
2005 Brockington A, Kirby J, Eggitt D, Schofield E, Morris C, Lewis CE, Ince PG, Shaw PJ. Screening of the regulatory and coding regions of vascular endothelial growth factor in amyotrophic lateral sclerosis. Neurogenetics. 6: 101-4. PMID 15776280 DOI: 10.1007/s10048-004-0201-4  0.01
2005 Wegel E, Shaw PJ. Chromosome organization in wheat endosperm and embryo. Cytogenetic and Genome Research. 109: 175-80. PMID 15753574 DOI: 10.1159/000082397  0.01
2005 Nath CE, Shaw PJ, Montgomery K, Earl JW. Melphalan pharmacokinetics in children with malignant disease: influence of body weight, renal function, carboplatin therapy and total body irradiation. British Journal of Clinical Pharmacology. 59: 314-24. PMID 15752378 DOI: 10.1111/j.1365-2125.2004.02319.x  0.01
2005 Brown JW, Shaw PJ, Shaw P, Marshall DF. Arabidopsis nucleolar protein database (AtNoPDB). Nucleic Acids Research. 33: D633-6. PMID 15608277 DOI: 10.1093/nar/gki052  0.01
2004 Graham JM, Papadakis N, Evans J, Widjaja E, Romanowski CA, Paley MN, Wallis LI, Wilkinson ID, Shaw PJ, Griffiths PD. Diffusion tensor imaging for the assessment of upper motor neuron integrity in ALS. Neurology. 63: 2111-9. PMID 15596758  0.01
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