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Markus Britschgi, Ph.D. - Publications

Affiliations: 
Roche, Indianapolis, IN, United States 
Area:
Neuroimmunology, neurodegeneration, aging
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Grathwohl S, Quansah E, Maroof N, Steiner JA, Spycher L, Benmansour F, Duran-Pacheco G, Siebourg-Polster J, Oroszlan-Szovik K, Remy H, Haenggi M, Stawiski M, Selhausen M, Mailver P, Wolfert A, ... ... Britschgi M, et al. Specific immune modulation of experimental colitis drives enteric alpha-synuclein accumulation and triggers age-related Parkinson-like brain pathology. Free Neuropathology. 2. PMID 37284635 DOI: 10.17879/freeneuropathology-2021-3326  0.744
2020 Brigger D, Riether C, van Brummelen R, Mosher KI, Shiu A, Ding Z, Zbären N, Gasser P, Guntern P, Yousef H, Castellano JM, Storni F, Graff-Radford N, Britschgi M, Grandgirard D, et al. Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nature Metabolism. PMID 32694825 DOI: 10.1038/s42255-020-0228-3  0.73
2020 Brüll M, Spreng AS, Gutbier S, Loser D, Krebs A, Reich M, Kraushaar U, Britschgi M, Patsch C, Leist M. Incorporation of stem cell-derived astrocytes into neuronal organoids to allow neuro-glial interactions in toxicological studies. Altex. PMID 32150624 DOI: 10.14573/Altex.1911111  0.324
2019 Shahmoradian SH, Lewis AJ, Genoud C, Hench J, Moors TE, Navarro PP, Castaño-Díez D, Schweighauser G, Graff-Meyer A, Goldie KN, Sütterlin R, Huisman E, Ingrassia A, Gier Y, Rozemuller AJM, ... ... Britschgi M, et al. Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes. Nature Neuroscience. 22: 1099-1109. PMID 31235907 DOI: 10.1038/S41593-019-0423-2  0.377
2018 Navarro PP, Genoud C, Castaño-Díez D, Graff-Meyer A, Lewis AJ, de Gier Y, Lauer ME, Britschgi M, Bohrmann B, Frank S, Hench J, Schweighauser G, Rozemuller AJM, van de Berg WDJ, Stahlberg H, et al. Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles. Scientific Reports. 8: 18046. PMID 30575769 DOI: 10.1038/S41598-018-36223-4  0.324
2018 Guerrero-Ferreira R, Taylor NMI, Mona D, Ringler P, Lauer ME, Riek R, Britschgi M, Stahlberg H. Cryo-EM structure of alpha-synuclein fibrils. Elife. 7. PMID 29969391 DOI: 10.7554/Elife.36402  0.303
2017 Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, et al. Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity. The Journal of Experimental Medicine. PMID 28298456 DOI: 10.1084/Jem.20162011  0.765
2016 Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, et al. Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Molecular Neurodegeneration. 11: 42. PMID 27216421 DOI: 10.1186/S13024-016-0105-4  0.73
2016 Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, et al. Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Molecular Neurodegeneration. 11: 31. PMID 27112350 DOI: 10.1186/S13024-016-0095-2  0.756
2015 Lehallier B, Essioux L, Gayan J, Alexandridis R, Nikolcheva T, Wyss-Coray T, Britschgi M. Combined Plasma and Cerebrospinal Fluid Signature for the Prediction of Midterm Progression From Mild Cognitive Impairment to Alzheimer Disease. Jama Neurology. 1-10. PMID 26659895 DOI: 10.1001/Jamaneurol.2015.3135  0.564
2014 Knuesel I, Chicha L, Britschgi M, Schobel SA, Bodmer M, Hellings JA, Toovey S, Prinssen EP. Maternal immune activation and abnormal brain development across CNS disorders. Nature Reviews. Neurology. 10: 643-60. PMID 25311587 DOI: 10.1038/Nrneurol.2014.187  0.341
2013 Grathwohl SA, Steiner JA, Britschgi M, Brundin P. Mind the gut: secretion of α-synuclein by enteric neurons. Journal of Neurochemistry. 125: 487-90. PMID 23448303 DOI: 10.1111/Jnc.12191  0.702
2013 Luo J, Elwood F, Britschgi M, Villeda S, Zhang H, Ding Z, Zhu L, Alabsi H, Getachew R, Narasimhan R, Wabl R, Fainberg N, James ML, Wong G, Relton J, et al. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival. The Journal of Experimental Medicine. 210: 157-72. PMID 23296467 DOI: 10.1084/Jem.20120412  0.719
2013 Lema Tomé CM, Tyson T, Rey NL, Grathwohl S, Britschgi M, Brundin P. Inflammation and α-synuclein's prion-like behavior in Parkinson's disease--is there a link? Molecular Neurobiology. 47: 561-74. PMID 22544647 DOI: 10.1007/S12035-012-8267-8  0.734
2012 Britschgi M, Takeda-Uchimura Y, Rockenstein E, Johns H, Masliah E, Wyss-Coray T. Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice. Journal of Neuroinflammation. 9: 220. PMID 22989354 DOI: 10.1186/1742-2094-9-220  0.598
2012 Hosono-Fukao T, Ohtake-Niimi S, Hoshino H, Britschgi M, Akatsu H, Hossain MM, Nishitsuji K, van Kuppevelt TH, Kimata K, Michikawa M, Wyss-Coray T, Uchimura K. Heparan sulfate subdomains that are degraded by Sulf accumulate in cerebral amyloid ß plaques of Alzheimer's disease: evidence from mouse models and patients. The American Journal of Pathology. 180: 2056-67. PMID 22429964 DOI: 10.1016/J.Ajpath.2012.01.015  0.601
2011 Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 477: 90-4. PMID 21886162 DOI: 10.1038/Nature10357  0.731
2011 Britschgi M, Rufibach K, Huang SL, Clark CM, Kaye JA, Li G, Peskind ER, Quinn JF, Galasko DR, Wyss-Coray T. Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome. Molecular & Cellular Proteomics : McP. 10: M111.008862. PMID 21742799 DOI: 10.1074/Mcp.M111.008862  0.622
2011 Moriyama M, Fukuhara T, Britschgi M, He Y, Narasimhan R, Villeda S, Molina H, Huber BT, Holers M, Wyss-Coray T. Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3981-9. PMID 21411641 DOI: 10.1523/Jneurosci.3617-10.2011  0.704
2009 Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, et al. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 12145-50. PMID 19581601 DOI: 10.1073/Pnas.0904866106  0.554
2009 Britschgi M, Wyss-Coray T. Blood protein signature for the early diagnosis of Alzheimer disease. Archives of Neurology. 66: 161-5. PMID 19064741 DOI: 10.1001/Archneurol.2008.530  0.568
2008 Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. The Journal of Clinical Investigation. 118: 2190-9. PMID 18497889 DOI: 10.1172/Jci33585  0.772
2008 Britschgi M, Olin CE, Johns H, Takeda-Uchimura Y, Rufibach K, Tomooka B, Robinson WH, Rajadas J, Clark CM, Fagan AM, Galasko DG, Holtzman DM, Jutel M, Leszek J, Li G, et al. P2-294: Microarray profiling reveals autoantibody reactivities against abnormal amyloid peptide conformations decline with age and in Alzheimer's disease Alzheimer's & Dementia. 4: T458-T459. DOI: 10.1016/J.Jalz.2008.05.1370  0.575
2007 Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, Friedman LF, Galasko DR, Jutel M, Karydas A, Kaye JA, Leszek J, Miller BL, Minthon L, Quinn JF, et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nature Medicine. 13: 1359-62. PMID 17934472 DOI: 10.1038/Nm1653  0.609
2007 Britschgi M, Wyss-Coray T. Systemic and acquired immune responses in Alzheimer's disease. International Review of Neurobiology. 82: 205-33. PMID 17678963 DOI: 10.1016/S0074-7742(07)82011-3  0.606
2007 Britschgi M, Wyss-Coray T. Immune cells may fend off Alzheimer disease. Nature Medicine. 13: 408-9. PMID 17415372 DOI: 10.1038/Nm0407-408  0.586
2007 Ray S, Wyss-Coray T, Britschgi M. S2-02-04: Plasma protein biomarkers to predict early Alzheimer's disease Alzheimer's & Dementia. 3: S181-S181. DOI: 10.1016/J.Jalz.2007.04.056  0.564
2006 Keller M, Spanou Z, Schaerli P, Britschgi M, Yawalkar N, Seitz M, Villiger PM, Pichler WJ. T-Cell Regulated Neutrophilic Inflammation in Auto-Inflammatory Diseases The Journal of Allergy and Clinical Immunology. 117. DOI: 10.1016/J.Jaci.2005.12.087  0.31
2005 Keller M, Spanou Z, Schaerli P, Britschgi M, Yawalkar N, Seitz M, Villiger PM, Pichler WJ. T cell-regulated neutrophilic inflammation in autoinflammatory diseases. Journal of Immunology (Baltimore, Md. : 1950). 175: 7678-86. PMID 16301678 DOI: 10.4049/Jimmunol.175.11.7678  0.302
2004 Schaerli P, Britschgi M, Keller M, Steiner UC, Steinmann LS, Moser B, Pichler WJ. Characterization of human T cells that regulate neutrophilic skin inflammation. Journal of Immunology (Baltimore, Md. : 1950). 173: 2151-8. PMID 15265952 DOI: 10.4049/Jimmunol.173.3.2151  0.303
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