☰

cached image

Roger E. Koeppe, II - Publications

Affiliations: 
Chemistry and Biochemistry University of Arkansas, Little Rock, AR 
Area:
Protein Engineering and Protein/Lipid Interactions
Website:
http://chemistry.uark.edu/4869.php
Tree Info Similar researchers PubMed Report error

206 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pal S, Koeppe RE, Chattopadhyay A. Membrane electrostatics sensed by tryptophan anchors in hydrophobic model peptides depends on non-aromatic interfacial amino acids: implications in hydrophobic mismatch. Faraday Discussions. PMID 34549729 DOI: 10.1039/d0fd00065e  0.402
2021 Price JR, Afrose F, Greathouse DV, Koeppe RE. Illuminating Disorder Induced by Glu in a Stable Arg-Anchored Transmembrane Helix. Acs Omega. 6: 20611-20618. PMID 34396006 DOI: 10.1021/acsomega.1c02800  0.344
2021 McKay MJ, Marr KA, Price JR, Greathouse DV, Koeppe RE. Lipid-Dependent Titration of Glutamic Acid at a Bilayer Membrane Interface. Acs Omega. 6: 8488-8494. PMID 33817510 DOI: 10.1021/acsomega.1c00276  0.334
2020 Afrose F, Martfeld AN, Greathouse DV, Koeppe RE. Examination of pH dependency and orientation differences of membrane spanning alpha helices carrying a single or pair of buried histidine residues. Biochimica Et Biophysica Acta. Biomembranes. 1863: 183501. PMID 33130099 DOI: 10.1016/j.bbamem.2020.183501  0.329
2020 McKay MJ, Greathouse DV, Koeppe RE. Flanking aromatic residue competition influences transmembrane peptide helix dynamics. Febs Letters. PMID 32931020 DOI: 10.1002/1873-3468.13926  0.412
2020 Sustich SJ, Afrose F, Greathouse DV, Koeppe RE. Influence of interfacial tryptophan residues on an arginine-flanked transmembrane helix. Biochimica Et Biophysica Acta. Biomembranes. 1862: 183134. PMID 31738898 DOI: 10.1016/J.Bbamem.2019.183134  0.446
2020 Marr KA, McKay M, Greathouse DV, Koeppe RE. Effect of pH and Lipid Composition on Membrane-Spanning Helices with Glutamic Acid Examined by Solid-State Nmr Biophysical Journal. 118: 393a. DOI: 10.1016/J.Bpj.2019.11.2235  0.382
2020 Koeppe RE, McKay MJ. Lipid-Dependent Titration of Glutamic Acid at a Membrane Interface Biophysical Journal. 118: 392a-393a. DOI: 10.1016/J.Bpj.2019.11.2234  0.37
2020 Nunn B, McKay M, Greathouse DV, Koeppe RE. Effect of Charged Lipids on the Ionization Behavior of Glutamic Acid-Containing Transmembrane Helices Biophysical Journal. 118: 391a. DOI: 10.1016/J.Bpj.2019.11.2228  0.326
2019 McKay MJ, Fu R, Greathouse DV, Koeppe RE. Breaking the Backbone: Central Arginine Residues Induce Membrane Exit and Helix Distortions Within a Dynamic Membrane Peptide. The Journal of Physical Chemistry. B. PMID 31483653 DOI: 10.1021/Acs.Jpcb.9B06034  0.432
2019 Greathouse D, Lipinski K, McKay MJ, Afrose F, Martfeld AN, Koeppe RE. Influence of Lipid Saturation, Hydrophobic Length and Cholesterol on Double-Arginine-Containing Helical Peptides in Bilayer Membranes. Chembiochem : a European Journal of Chemical Biology. PMID 31150136 DOI: 10.1002/Cbic.201900282  0.491
2019 Kapoor R, Peyear TA, Koeppe RE, Andersen OS. Antidepressants are modifiers of lipid bilayer properties. The Journal of General Physiology. 151: 342-356. PMID 30796095 DOI: 10.1085/Jgp.201812263  0.434
2019 Marr KA, McKay MJ, Greathouse DV, Koeppe RE. Lipid Optimization to Improve the Solid-State NMR Spectra from Membrane-Spanning Helices with Glutamic Acid Biophysical Journal. 116: 517a. DOI: 10.1016/J.Bpj.2018.11.2789  0.384
2019 McKay MJ, Greathouse DV, Koeppe RE. Characterization of Alpha-Helix Distortions at a Membrane Surface and a Partial 3(10)-Helix by Solid-State NMR Biophysical Journal. 116: 517a. DOI: 10.1016/J.Bpj.2018.11.2788  0.341
2019 Sustich SJ, Afrose F, Greathouse DV, Koeppe RE. Helix Fraying and Orientation of a Transmembrane Peptide having a Long Hydrophobic Core and Anchored by Interfacial Arginine Residues Biophysical Journal. 116: 516a. DOI: 10.1016/J.Bpj.2018.11.2785  0.437
2019 Afrose F, Greathouse DV, Koeppe RE. Position Dependent Orientation Difference of Transmembrane Peptides Flanked by Single or Multiple Histidine Residues Biophysical Journal. 116: 516a. DOI: 10.1016/J.Bpj.2018.11.2784  0.429
2019 Nunn BE, McKay MJ, Greathouse DV, Koeppe RE. Influence of Charged Lipids on Glutamic Acid Containing Transmembrane Helices Biophysical Journal. 116: 516a. DOI: 10.1016/J.Bpj.2018.11.2783  0.333
2019 Brownd M, McKay MJ, Greathouse DV, Andersen OS, Koeppe RE. Novel F13,F15 Gramicidin Subunits Predicted to Cross Bilayer Membranes and form Ion Channels Biophysical Journal. 116: 512a. DOI: 10.1016/J.Bpj.2018.11.2762  0.338
2018 Afrose F, McKay MJ, Mortazavi A, Suresh Kumar V, Greathouse DV, Koeppe RE. Transmembrane Helix Integrity versus Fraying to Expose Hydrogen Bonds at a Membrane-Water Interface. Biochemistry. PMID 30565458 DOI: 10.1021/Acs.Biochem.8B01119  0.496
2018 Pal S, Koeppe RE, Chattopadhyay A. Wavelength-Selective Fluorescence of a Model Transmembrane Peptide: Constrained Dynamics of Interfacial Tryptophan Anchors. Journal of Fluorescence. PMID 30225736 DOI: 10.1007/S10895-018-2293-5  0.48
2018 Usery RD, Enoki TA, Wickramasinghe SP, Nguyen VP, Ackerman DG, Greathouse DV, Koeppe RE, Barrera FN, Feigenson GW. Membrane Bending Moduli of Coexisting Liquid Phases Containing Transmembrane Peptide. Biophysical Journal. 115: 164. PMID 29972808 DOI: 10.1016/j.bpj.2018.06.002  0.32
2018 McKay MJ, Martfeld AN, De Angelis AA, Opella SJ, Greathouse DV, Koeppe RE. Control of Transmembrane Helix Dynamics by Interfacial Tryptophan Residues. Biophysical Journal. 114: 2617-2629. PMID 29874612 DOI: 10.1016/J.Bpj.2018.04.016  0.506
2018 Usery RD, Enoki TA, Wickramasinghe SP, Nguyen VP, Ackerman DG, Greathouse DV, Koeppe RE, Barrera FN, Feigenson GW. Membrane Bending Moduli of Coexisting Liquid Phases Containing Transmembrane Peptide. Biophysical Journal. 114: 2152-2164. PMID 29742408 DOI: 10.1016/J.Bpj.2018.03.026  0.408
2018 McKay MJ, Afrose F, Koeppe RE, Greathouse DV. Helix formation and stability in membranes. Biochimica Et Biophysica Acta. PMID 29447916 DOI: 10.1016/J.Bbamem.2018.02.010  0.432
2018 Afrose F, Greathouse DV, Koeppe RE. Ionization and Dynamic Properties of Single and Multiple Histidine Residues on a Transmembrane Helical Backbone Biophysical Journal. 114: 458a. DOI: 10.1016/J.Bpj.2017.11.2530  0.345
2018 Sustich S, Afrose F, Greathouse DV, Koeppe RE. Detection of Helix Fraying of a Transmembrane Peptide with Two Interfacial Arginine Residues Biophysical Journal. 114: 458a. DOI: 10.1016/J.Bpj.2017.11.2529  0.418
2018 Lipinski KA, Martfeld AN, Greathouse DV, Koeppe RE. Influence of Saturation and Hydrophobic Length of Lipid Bilayers on Twin-Arginine Containing Helical Peptides Biophysical Journal. 114: 454a. DOI: 10.1016/J.Bpj.2017.11.2511  0.476
2018 Brownd M, McKay MJ, Greathouse DV, Andersen OS, Koeppe RE. Gramicidin Subunits that Cross Membranes and form Ion Channels Biophysical Journal. 114: 454a. DOI: 10.1016/J.Bpj.2017.11.2509  0.39
2017 Lum K, Ingólfsson HI, Koeppe RE, Andersen OS. Exchange of Gramicidin between Lipid Bilayers: Implications for the Mechanism of Channel Formation. Biophysical Journal. 113: 1757-1767. PMID 29045870 DOI: 10.1016/J.Bpj.2017.08.049  0.38
2017 Beaven AH, Sodt AJ, Pastor RW, Koeppe RE, Andersen OS, Im W. Characterizing Residue-Bilayer Interactions Using Gramicidin A as a Scaffold and Tryptophan Substitutions as Probes. Journal of Chemical Theory and Computation. PMID 28870079 DOI: 10.1021/Acs.Jctc.7B00400  0.435
2017 Rajagopalan V, Greathouse DV, Koeppe RE. Influence of glutamic acid residues and pH on the properties of transmembrane helices. Biochimica Et Biophysica Acta. PMID 28069412 DOI: 10.1016/J.Bbamem.2017.01.006  0.442
2017 Lipinski KA, Martfeld AN, Greathouse DV, Koeppe RE. Response of GWALP23 Transmembrane Peptides to Incorporation of Specific Pairs of Buried Charged Arginine Residues Biophysical Journal. 112: 528a. DOI: 10.1016/J.Bpj.2016.11.2858  0.393
2017 McKay MJ, Martfeld AN, De Angelis AA, Opella SJ, Greathouse DV, Koeppe RE. Interfacial Tryptophan Residues Govern Transmembrane Helix Dynamics Biophysical Journal. 112: 528a. DOI: 10.1016/J.Bpj.2016.11.2857  0.323
2017 Afrose F, Greathouse DV, Koeppe RE. Influence of Paired Histidine Residues on Transmembrane Helix Orientation and Dynamics Biophysical Journal. 112: 528a. DOI: 10.1016/J.Bpj.2016.11.2856  0.338
2017 Knobbe K, Rajagopalan V, Martfeld A, Greathouse D, Koeppe R. Solid-State NMR Investigations of Transmembrane Helix Interactions Biophysical Journal. 112: 528a. DOI: 10.1016/J.Bpj.2016.11.2855  0.31
2017 Paz Herrera A, Afrose F, Greathouse D, Koeppe R. Detection of Helix Fraying in Transmembrane Helices with Interfacial Histidine Residues Biophysical Journal. 112: 230a. DOI: 10.1016/J.Bpj.2016.11.1263  0.493
2016 Marquardt D, Heberle FA, Greathouse DV, Koeppe RE, Standaert RF, Van Oosten BJ, Harroun TA, Kinnun JJ, Williams JA, Wassall SR, Katsaras J. Lipid bilayer thickness determines cholesterol's location in model membranes. Soft Matter. PMID 27801465 DOI: 10.1039/C6Sm01777K  0.4
2016 Thibado JK, Martfeld AN, Greathouse DV, Koeppe RE. Influence of High pH and Cholesterol on Single Arginine-Containing Transmembrane Peptide Helices. Biochemistry. 55: 6337-6343. PMID 27782382 DOI: 10.1021/Acs.Biochem.6B00896  0.497
2016 Martfeld AN, Greathouse DV, Koeppe RE. Ionization Properties of Histidine Residues in the Lipid Bilayer Membrane Environment. The Journal of Biological Chemistry. 291: 19146-56. PMID 27440045 DOI: 10.1074/Jbc.M116.738583  0.479
2016 McKay MJ, Martfeld AN, Greathouse DV, Koeppe RE. Monitoring the Consequences of Relocating the Tryptophan Anchors on Transmembrane Peptide Dynamics and Alignment Biophysical Journal. 110: 75a. DOI: 10.1016/J.Bpj.2015.11.472  0.511
2016 Wendt RM, Rajagopalan V, Greathouse DV, Koeppe RE. Investigating Possible Interactions between Ionizable Residues in Model Transmembrane Peptides Biophysical Journal. 110: 253a. DOI: 10.1016/J.Bpj.2015.11.1392  0.448
2016 Mortazavi A, Rajagopalan V, Greathouse DV, Koeppe RE. Helix Fraying May Stabilize Transmembrane Alpha Helices Biophysical Journal. 110: 253a. DOI: 10.1016/J.Bpj.2015.11.1391  0.381
2016 Rajagopalan V, Greathouse DV, Koeppe RE. Varied Approaches to the Ionization Behavior of Specific Glu Residues that Face the Lipids in Transmembrane Helices Biophysical Journal. 110: 252a. DOI: 10.1016/J.Bpj.2015.11.1385  0.443
2016 Martfeld AN, Greathouse DV, Koeppe RE. Use of Transmembrane Peptides to Understand Ionization Properties of Histidine Residues in Lipid Bilayers Biophysical Journal. 110: 252a. DOI: 10.1016/J.Bpj.2015.11.1384  0.464
2016 Thibado JK, Martfeld AN, Greathouse DV, Koeppe RE. Cholesterol Influence on Arginine-Containing Transmembrane Peptides Biophysical Journal. 110: 251a. DOI: 10.1016/J.Bpj.2015.11.1383  0.471
2016 Afrose F, Greathouse DV, Koeppe RE. Solid-State NMR Investigations of a Transmembrane Peptide having Interfacial Histidine Residues Biophysical Journal. 110: 251a. DOI: 10.1016/J.Bpj.2015.11.1382  0.516
2015 Rusinova R, Koeppe RE, Andersen OS. A general mechanism for drug promiscuity: Studies with amiodarone and other antiarrhythmics. The Journal of General Physiology. PMID 26573624 DOI: 10.1016/J.Bpj.2015.11.492  0.393
2015 Martfeld AN, Rajagopalan V, Greathouse DV, Koeppe RE. Dynamic regulation of lipid-protein interactions. Biochimica Et Biophysica Acta. 1848: 1849-59. PMID 25666872 DOI: 10.1016/J.Bbamem.2015.01.019  0.453
2015 Whitlock SE, Koeppe RE, Greathouse DA. Comparing Peptide-Lipid Interactions and Antimicrobial Activities of Peptides with Similar “Core” Lengths But Variable Arginine and Tryptophan Residues Biophysical Journal. 108: 554a. DOI: 10.1016/J.Bpj.2014.11.3038  0.497
2015 Mortazavi A, Rajagopalan V, Greathouse DV, Koeppe RE. Detection of Helix Fraying in Designed Transmembrane Alpha Helices Biophysical Journal. 108: 554a. DOI: 10.1016/J.Bpj.2014.11.3037  0.47
2015 Rajagopalan V, Greathouse DV, Koeppe RE. Ionization-Dependent Behavior of Transmembrane Helices that Incorporate Glu or Tyr Residues Biophysical Journal. 108: 554a. DOI: 10.1016/J.Bpj.2014.11.3036  0.459
2015 Suresh Kumar V, Martfeld AN, Greathouse DV, Koeppe RE. Influence of a Potentially Destabilizing Central Tryptophan on Transmembrane Helix Domains Biophysical Journal. 108: 553a. DOI: 10.1016/J.Bpj.2014.11.3035  0.53
2015 Thibado JK, Martfeld AN, Greathouse DV, Koeppe RE. Influence of Cholesterol on Single Arginine-Containing Transmembrane Helical Peptides Biophysical Journal. 108: 553a. DOI: 10.1016/J.Bpj.2014.11.3034  0.507
2015 Martfeld AN, Greathouse DV, Koeppe RE. Response of GWALP Transmembrane Peptides to Incorporation of Buried Histidine Residues Biophysical Journal. 108: 553a. DOI: 10.1016/J.Bpj.2014.11.3033  0.438
2015 Rusinova R, Koeppe RE, Andersen OS. A General Mechanism for Off-Target Effects: Studies with Amiodarone and other Antiarrhythmics Biophysical Journal. 108: 498a. DOI: 10.1016/J.Bpj.2014.11.2724  0.405
2015 Greathouse DV, Kinnun JJ, Williams JA, Marquardt D, Klauda JB, Koeppe RE, Katsaras J, Harroun TA, Wassall SR. Disorderly Polyunsaturated Fatty Acids and Orderly Cholesterol: Just How do they get along in a Membrane? Biophysical Journal. 108: 412a. DOI: 10.1016/J.Bpj.2014.11.2259  0.384
2014 Sparks KA, Gleason NJ, Gist R, Langston R, Greathouse DV, Koeppe RE. Comparisons of interfacial Phe, Tyr, and Trp residues as determinants of orientation and dynamics for GWALP transmembrane peptides. Biochemistry. 53: 3637-45. PMID 24829070 DOI: 10.1021/Bi500439X  0.49
2014 Vorobyov I, Olson TE, Kim JH, Koeppe RE, Andersen OS, Allen TW. Ion-induced defect permeation of lipid membranes. Biophysical Journal. 106: 586-97. PMID 24507599 DOI: 10.1016/J.Bpj.2013.12.027  0.422
2014 Chaudhuri A, Haldar S, Sun H, Koeppe RE, Chattopadhyay A. Importance of indole N-H hydrogen bonding in the organization and dynamics of gramicidin channels. Biochimica Et Biophysica Acta. 1838: 419-28. PMID 24148157 DOI: 10.1016/J.Bbamem.2013.10.011  0.448
2014 Wood MK, Koeppe RE, Greathouse DV. Characterizing Moderately Short Antimicrobial Tryptophan/Arginine-Rich Peptides Biophysical Journal. 106: 96a-97a. DOI: 10.1016/J.Bpj.2013.11.604  0.469
2014 Beaven AH, Sodt AJ, Greathouse DV, Koeppe RE, Pastor RW, Andersen OS, Im W. All-Atom Simulation and Continuum Elastic Theory of Gramicidin a in Binary Component Lipid Bilayers Biophysical Journal. 106: 801a. DOI: 10.1016/J.Bpj.2013.11.4389  0.366
2014 Martfeld AN, Greathouse DV, Koeppe RE. Influence of pH and Histidine Residues on Membrane-Spanning Helical Peptides Biophysical Journal. 106: 712a. DOI: 10.1016/J.Bpj.2013.11.3938  0.441
2014 Rajagopalan V, Greathouse DV, Koeppe RE. Influence of Glutamic Acid Residues on the Properties of Model Membrane-Spanning Helices Biophysical Journal. 106: 711a-712a. DOI: 10.1016/J.Bpj.2013.11.3937  0.484
2014 Suresh Kumar V, Doss BP, Greathouse DV, Koeppe RE. Influence of a Central Tryptophan and of Cholesterol on the Properties of Defined Transmembrane Helical Peptides Biophysical Journal. 106: 711a. DOI: 10.1016/J.Bpj.2013.11.3935  0.512
2013 Gleason NJ, Greathouse DV, Grant CV, Opella SJ, Koeppe RE. Single tryptophan and tyrosine comparisons in the N-terminal and C-terminal interface regions of transmembrane GWALP peptides. The Journal of Physical Chemistry. B. 117: 13786-94. PMID 24111589 DOI: 10.1021/Jp407542E  0.502
2013 Bruno MJ, Rusinova R, Gleason NJ, Koeppe RE, Andersen OS. Interactions of drugs and amphiphiles with membranes: modulation of lipid bilayer elastic properties by changes in acyl chain unsaturation and protonation. Faraday Discussions. 161: 461-80; discussion 5. PMID 23805753 DOI: 10.1039/C2Fd20092A  0.401
2013 Rusinova R, Hobart EA, Koeppe RE, Andersen OS. Phosphoinositides alter lipid bilayer properties. The Journal of General Physiology. 141: 673-90. PMID 23712549 DOI: 10.1085/Jgp.201310960  0.44
2013 Gleason NJ, Vostrikov VV, Greathouse DV, Koeppe RE. Buried lysine, but not arginine, titrates and alters transmembrane helix tilt. Proceedings of the National Academy of Sciences of the United States of America. 110: 1692-5. PMID 23319623 DOI: 10.1073/Pnas.1215400110  0.465
2013 Rajagopalan V, Greathouse DV, Koeppe RE. Influence of pH and Side-Chain Negative Charge on the Behavior of Designed Transmembrane Peptides in Lipid Bilayers Biophysical Journal. 104: 92a. DOI: 10.1016/J.Bpj.2012.11.552  0.515
2013 Sanford RL, Al'Aref SJ, Koeppe RE, Andersen OS. Statins Alter Lipid Bilayer Properties Biophysical Journal. 104: 86a. DOI: 10.1016/J.Bpj.2012.11.515  0.319
2013 Martfeld AN, Greathouse DV, Koeppe RE. Influence of Histidine Residues on Transmembrane Helix Alignment Biophysical Journal. 104: 597a. DOI: 10.1016/J.Bpj.2012.11.3316  0.441
2012 Rankenberg JM, Vostrikov VV, Greathouse DV, Grant CV, Opella SJ, Koeppe RE. Properties of membrane-incorporated WALP peptides that are anchored on only one end. Biochemistry. 51: 10066-74. PMID 23171005 DOI: 10.1021/Bi301394Z  0.812
2012 Vostrikov VV, Hall BA, Sansom MSP, Koeppe RE. Accommodation of a central arginine in a transmembrane peptide by changing the placement of anchor residues Journal of Physical Chemistry B. 116: 12980-12990. PMID 23030363 DOI: 10.1021/Jp308182B  0.496
2012 Haldar S, Chaudhuri A, Gu H, Koeppe RE, Kombrabail M, Krishnamoorthy G, Chattopadhyay A. Membrane organization and dynamics of "inner pair" and "outer pair" tryptophan residues in gramicidin channels. The Journal of Physical Chemistry. B. 116: 11056-64. PMID 22892073 DOI: 10.1021/Jp304846F  0.463
2012 Rankenberg JM, Vostrikov VV, DuVall CD, Greathouse DV, Koeppe RE, Grant CV, Opella SJ. Proline kink angle distributions for GWALP23 in lipid bilayers of different thicknesses. Biochemistry. 51: 3554-64. PMID 22489564 DOI: 10.1021/Bi300281K  0.819
2012 Gleason NJ, Vostrikov VV, Greathouse DV, Grant CV, Opella SJ, Koeppe RE. Tyrosine replacing tryptophan as an anchor in GWALP peptides. Biochemistry. 51: 2044-53. PMID 22364236 DOI: 10.1021/Bi201732E  0.502
2012 Vostrikov V, Courtney J, Hinton J, Koeppe R. 1H and 15N assignments of WALP19-P10 peptide in SDS micelles Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lcn/Pdb  0.37
2012 Sanford RL, Al'Aref SJ, Koeppe RE, Andersen OS. Statins Modify Lipid Bilayer Properties Biophysical Journal. 102: 84a. DOI: 10.1016/J.Bpj.2011.11.484  0.311
2012 Bell-Cohn AJ, Gleason NJ, Koeppe RE, Greathouse DV. Characterization of Antimicrobial Peptides Relating to Shortened RWALP Model Peptides Biophysical Journal. 102: 76a. DOI: 10.1016/J.Bpj.2011.11.445  0.497
2012 Gleason NJ, Vostrikov VV, Greathouse DV, Koeppe RE. Response of GWALP Transmembrane Peptides to Titration of a Buried Lysine Biophysical Journal. 102: 76a. DOI: 10.1016/J.Bpj.2011.11.444  0.499
2012 Gist RR, Gleason NJ, Langston R, Sparks K, Greathouse DV, Koeppe RE. Importance of Aromatic Anchor Residue Identity and Location for the Tilt and Dynamics of Transmembrane Peptides Biophysical Journal. 102: 76a. DOI: 10.1016/J.Bpj.2011.11.443  0.514
2012 Vorobyov I, Koeppe R, Andersen OS, Allen TW. Origins of Non-Selective Ion Transport across Lipid Bilayers Biophysical Journal. 102: 335a. DOI: 10.1016/J.Bpj.2011.11.1834  0.41
2011 Vostrikov VV, Grant CV, Opella SJ, Koeppe RE. On the combined analysis of ²H and ¹⁵N/¹H solid-state NMR data for determination of transmembrane peptide orientation and dynamics. Biophysical Journal. 101: 2939-47. PMID 22208192 DOI: 10.1016/J.Bpj.2011.11.008  0.485
2011 Ingólfsson HI, Koeppe RE, Andersen OS. Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties. Febs Letters. 585: 3101-5. PMID 21896274 DOI: 10.1016/J.Febslet.2011.08.040  0.375
2011 Vostrikov VV, Koeppe RE. Response of GWALP transmembrane peptides to changes in the tryptophan anchor positions. Biochemistry. 50: 7522-35. PMID 21800919 DOI: 10.1021/Bi2006459  0.52
2011 Ingólfsson HI, Li Y, Vostrikov VV, Gu H, Hinton JF, Koeppe RE, Roux B, Andersen OS. Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. I: molecular dynamics simulations. The Journal of Physical Chemistry. B. 115: 7417-26. PMID 21574563 DOI: 10.1021/Jp200904D  0.401
2011 Vostrikov VV, Gu H, Ingólfsson HI, Hinton JF, Andersen OS, Roux B, Koeppe RE. Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. II: nuclear magnetic resonance experiments. The Journal of Physical Chemistry. B. 115: 7427-32. PMID 21574558 DOI: 10.1021/Jp200906Y  0.349
2011 Gu H, Lum K, Kim JH, Greathouse DV, Andersen OS, Koeppe RE. The membrane interface dictates different anchor roles for "inner pair" and "outer pair" tryptophan indole rings in gramicidin A channels. Biochemistry. 50: 4855-66. PMID 21539360 DOI: 10.1021/Bi200136E  0.39
2011 Vostrikov VV, Grant CV, Opella SJ, Koeppe RE. On the Treatment of Dynamics During Combined 2H GALA and 15N/1H PISEMA Analysis of Transmembrane Peptide Tilt using Solid-State NMR Data Biophysical Journal. 100: 638a. DOI: 10.1016/J.Bpj.2010.12.3667  0.465
2011 DuVall CD, Vostrikov VV, Greathouse DV, Koeppe RE. Influence of Glycine Substitutions on Designed Proline-Containing Transmembrane Peptides Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3655  0.461
2011 Courtney JM, Vostrikov VV, Hinton JF, Koeppe RE. Comparison of Proline Substitutions at Positions 8 and 10 in WALP19 Biophysical Journal. 100: 636a. DOI: 10.1016/J.Bpj.2010.12.3654  0.401
2011 Gleason NJ, Greathouse DV, Koeppe RE. Using Tyrosine to Anchor a Transmembrane Peptide Biophysical Journal. 100: 635a-636a. DOI: 10.1016/J.Bpj.2010.12.3653  0.514
2011 Koeppe RE, Froyd-Rankenberg JM, Vostrikov VV, DuVall CD, Greathouse DV, Grant CV, Opella SJ. A Proline Kink in GWALP23 Biophysical Journal. 100: 525a. DOI: 10.1016/J.Bpj.2010.12.3072  0.495
2011 Al'Aref SJ, Sanford RL, Koeppe RE, Andersen OS. Statins Modify Bilayer Mechanical Properties Biophysical Journal. 100: 500a. DOI: 10.1016/J.Bpj.2010.12.2928  0.42
2011 Sanford RL, Al'Aref SJ, Koeppe RE, Andersen OS. Fenamates Alter Bilayer Properties Biophysical Journal. 100: 500a. DOI: 10.1016/J.Bpj.2010.12.2927  0.408
2010 Lundbaek JA, Koeppe RE, Andersen OS. Amphiphile regulation of ion channel function by changes in the bilayer spring constant. Proceedings of the National Academy of Sciences of the United States of America. 107: 15427-30. PMID 20713738 DOI: 10.1073/Pnas.1007455107  0.431
2010 Daily AE, Kim JH, Greathouse DV, Andersen OS, Koeppe RE. Polar groups in membrane channels: consequences of replacing alanines with serines in membrane-spanning gramicidin channels. Biochemistry. 49: 6856-65. PMID 20695525 DOI: 10.1021/Bi100857G  0.427
2010 Yu H, Mazzanti CL, Whitfield TW, Koeppe RE, Andersen OS, Roux B. A combined experimental and theoretical study of ion solvation in liquid N-methylacetamide. Journal of the American Chemical Society. 132: 10847-56. PMID 20681718 DOI: 10.1021/Ja103270W  0.757
2010 Vostrikov VV, Daily AE, Greathouse DV, Koeppe RE. Charged or aromatic anchor residue dependence of transmembrane peptide tilt. The Journal of Biological Chemistry. 285: 31723-30. PMID 20667827 DOI: 10.1074/Jbc.M110.152470  0.517
2010 Vostrikov VV, Hall BA, Greathouse DV, Koeppe RE, Sansom MSP. Changes in transmembrane helix alignment by arginine residues revealed by solid-state NMR experiments and coarse-grained MD simulations Journal of the American Chemical Society. 132: 5803-5811. PMID 20373735 DOI: 10.1021/Ja100598E  0.462
2010 Froyd-Rankenberg JM, Greathouse DV, Koeppe RE. Influence of WALP Peptides on Phase Behavior of Cholesterol Containing Ternary Lipid Mixtures Biophysical Journal. 98: 91a. DOI: 10.1016/J.Bpj.2009.12.516  0.468
2010 Vostrikov VV, Daily AE, Greathouse DV, Koeppe R. Charged and Aromatic Anchoring Amino Acids Affect the Orientation of Transmembrane Peptides: A Deuterium NMR Study Biophysical Journal. 98: 91a. DOI: 10.1016/J.Bpj.2009.12.515  0.48
2010 Gleason NJ, Vostrikov VV, Koeppe RE. Observation of Backbone Cα-Deuteron Signals in Solid-State NMR Spectra of Labeled Alanines in Oriented Transmembrane Peptides Biophysical Journal. 98: 91a. DOI: 10.1016/J.Bpj.2009.12.514  0.465
2010 Hall BA, Vostrikov VV, Koeppe RE, Sansom MS. Sensitivity of Coarse Grain Models of Peptides to the Introduction of Charged Residues in Model Peptides and Bacterial Chemoreceptors Biophysical Journal. 98: 644a. DOI: 10.1016/J.Bpj.2009.12.3530  0.445
2010 Al'Aref SJ, Koeppe RE, Andersen OS. NSAIDs Alter Bilayer Properties by a Common Mechanism Biophysical Journal. 98: 480a. DOI: 10.1016/J.Bpj.2009.12.2613  0.426
2010 Rusinova R, Herold KF, Koeppe RE, Hemmings H, Andersen OS. Thiazolidinediones Alter Lipid Bilayer Properties and Native Voltage-Gated Sodium Channel Function Biophysical Journal. 98: 480a. DOI: 10.1016/J.Bpj.2009.12.2612  0.415
2010 Kapoor R, Ingolfsson HI, Koeppe RE, Andersen O. Antidepressants Modify Lipid Bilayer Properties Biophysical Journal. 98: 479a-480a. DOI: 10.1016/J.Bpj.2009.12.2611  0.427
2009 Thomas R, Vostrikov VV, Greathouse DV, Koeppe RE. Influence of proline upon the folding and geometry of the WALP19 transmembrane peptide. Biochemistry. 48: 11883-91. PMID 19891499 DOI: 10.1021/Bi9016395  0.506
2009 Rusinova R, Koeppe RE, Andersen OS. The Insulin-sensitizers Troglitazone And Rosiglitazone Alter Lipid Bilayer Properties Biophysical Journal. 96: 158a. DOI: 10.1016/J.Bpj.2008.12.720  0.392
2009 Ingolfsson HI, Vostrikov VV, Gu H, Koeppe RE, Hinton JF, Roux B, Allen TW, Andersen OS. Evaluating Gramicidin A Channel Backbone Dynamics by Molecular Dynamics and Nuclear Magnetic Resonance Biophysical Journal. 96: 152a-153a. DOI: 10.1016/J.Bpj.2008.12.688  0.423
2009 Al'Aref SJ, Andersen OS, Koeppe RE. NSAIDs Alter Lipid Bilayer Mechanical Properties Biophysical Journal. 96: 150a. DOI: 10.1016/J.Bpj.2008.12.676  0.397
2009 Yu H, Whitfield TW, Noskov SY, Mazzanti CL, Koeppe RE, Andersen OS, Roux B. Development of a Drude Polarizable Force Field for Ion-water and Ion-NMA Interactions and Application to Selectivity in Ion Channels Biophysical Journal. 96: 660a. DOI: 10.1016/J.Bpj.2008.12.3488  0.742
2009 Froyd-Rankenberg JM, Greathouse DV, Koeppe RE. Half-Anchored WALP Peptides: Effect Of Anchor Position On Peptide Orientation Biophysical Journal. 96: 455a-456a. DOI: 10.1016/J.Bpj.2008.12.2342  0.507
2009 Gleason NJ, Vostrikov VV, Koeppe RE. Comparison of Mechanical and Magnetic Alignment of WALP-like Peptides for Solid-State NMR Biophysical Journal. 96: 455a. DOI: 10.1016/J.Bpj.2008.12.2341  0.473
2009 Vostrikov VV, Greathouse DV, Koeppe RE. Use of Transmembrane Peptides to Investigate Arginine Interactions with Lipid Bilayers Biophysical Journal. 96: 455a. DOI: 10.1016/J.Bpj.2008.12.2339  0.449
2009 Mazzanti CL, Greathouse DV, Hinton JF, Lemmons JD, Koeppe RE. Conformation of the Transmembrane Domain of the Anthrax Toxin Receptor Biophysical Journal. 96: 454a. DOI: 10.1016/J.Bpj.2008.12.2334  0.772
2009 Vostrikov VV, Grant CV, Opella SJ, Koeppe RE. Orientation of Single-Span Transmembrane Peptides Investigated by Independent Solid-State NMR Methods: GALA and PISEMA Biophysical Journal. 96: 454a. DOI: 10.1016/J.Bpj.2008.12.2333  0.475
2008 Vostrikov VV, Grant CV, Daily AE, Opella SJ, Koeppe RE. Comparison of "Polarization inversion with spin exchange at magic angle" and "geometric analysis of labeled alanines" methods for transmembrane helix alignment. Journal of the American Chemical Society. 130: 12584-5. PMID 18763771 DOI: 10.1021/Ja803734K  0.367
2008 Sun H, Greathouse DV, Andersen OS, Koeppe RE. The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels. The Journal of Biological Chemistry. 283: 22233-43. PMID 18550546 DOI: 10.1074/Jbc.M802074200  0.451
2008 Chattopadhyay A, Rawat SS, Greathouse DV, Kelkar DA, Koeppe RE. Role of tryptophan residues in gramicidin channel organization and function. Biophysical Journal. 95: 166-75. PMID 18339735 DOI: 10.1529/Biophysj.107.124206  0.458
2008 Holt A, de Almeida RF, Nyholm TK, Loura LM, Daily AE, Staffhorst RW, Rijkers DT, Koeppe RE, Prieto M, Killian JA. Is there a preferential interaction between cholesterol and tryptophan residues in membrane proteins? Biochemistry. 47: 2638-49. PMID 18215073 DOI: 10.1021/Bi702235K  0.446
2008 Daily AE, Greathouse DV, van der Wel PC, Koeppe RE. Helical distortion in tryptophan- and lysine-anchored membrane-spanning alpha-helices as a function of hydrophobic mismatch: a solid-state deuterium NMR investigation using the geometric analysis of labeled alanines method. Biophysical Journal. 94: 480-91. PMID 17827234 DOI: 10.1529/Biophysj.106.097543  0.762
2007 Andersen OS, Bruno MJ, Sun H, Koeppe RE. Single-molecule methods for monitoring changes in bilayer elastic properties. Methods in Molecular Biology (Clifton, N.J.). 400: 543-70. PMID 17951759 DOI: 10.1007/978-1-59745-519-0_37  0.421
2007 Ingolfsson HI, Koeppe RE, Andersen OS. Curcumin is a modulator of bilayer material properties. Biochemistry. 46: 10384-91. PMID 17705403 DOI: 10.1021/Bi701013N  0.406
2007 Bruno MJ, Koeppe RE, Andersen OS. Docosahexaenoic acid alters bilayer elastic properties. Proceedings of the National Academy of Sciences of the United States of America. 104: 9638-43. PMID 17535898 DOI: 10.1073/Pnas.0701015104  0.419
2007 van der Wel PC, Reed ND, Greathouse DV, Koeppe RE. Orientation and motion of tryptophan interfacial anchors in membrane-spanning peptides. Biochemistry. 46: 7514-24. PMID 17530863 DOI: 10.1021/Bi700082V  0.766
2007 Andersen OS, Koeppe RE. Bilayer thickness and membrane protein function: an energetic perspective. Annual Review of Biophysics and Biomolecular Structure. 36: 107-30. PMID 17263662 DOI: 10.1146/Annurev.Biophys.36.040306.132643  0.4
2006 Siegel DP, Cherezov V, Greathouse DV, Koeppe RE, Killian JA, Caffrey M. Transmembrane peptides stabilize inverted cubic phases in a biphasic length-dependent manner: implications for protein-induced membrane fusion. Biophysical Journal. 90: 200-11. PMID 16214859 DOI: 10.1529/Biophysj.105.070466  0.466
2006 Ashrafuzzaman M, Lampson MA, Greathouse DV, Koeppe RE, Andersen OS. Manipulating lipid bilayer material properties using biologically active amphipathic molecules Journal of Physics Condensed Matter. 18: S1235-S1255. DOI: 10.1088/0953-8984/18/28/S08  0.404
2006 Anastasiadis A, Morton CJ, Talbo GH, Koeppe RE, Separovic F. Effect of linker length on avidin binding to biotinylated gramicidin A International Journal of Peptide Research and Therapeutics. 12: 243-252. DOI: 10.1007/S10989-006-9017-4  0.387
2005 Pulay P, Scherer EM, van der Wel PC, Koeppe RE. Importance of tensor asymmetry for the analysis of 2H NMR spectra from deuterated aromatic rings. Journal of the American Chemical Society. 127: 17488-93. PMID 16332101 DOI: 10.1021/Ja054935X  0.704
2005 Lundbaek JA, Birn P, Tape SE, Toombes GE, Søgaard R, Koeppe RE, Gruner SM, Hansen AJ, Andersen OS. Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity. Molecular Pharmacology. 68: 680-9. PMID 15967874 DOI: 10.1124/Mol.105.013573  0.426
2004 Suchyna TM, Tape SE, Koeppe RE, Andersen OS, Sachs F, Gottlieb PA. Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers. Nature. 430: 235-40. PMID 15241420 DOI: 10.1038/Nature02743  0.478
2004 Strandberg E, Ozdirekcan S, Rijkers DT, van der Wel PC, Koeppe RE, Liskamp RM, Killian JA. Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR. Biophysical Journal. 86: 3709-21. PMID 15189867 DOI: 10.1529/Biophysj.103.035402  0.76
2004 Lundbaek JA, Birn P, Hansen AJ, Søgaard R, Nielsen C, Girshman J, Bruno MJ, Tape SE, Egebjerg J, Greathouse DV, Mattice GL, Koeppe RE, Andersen OS. Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol. The Journal of General Physiology. 123: 599-621. PMID 15111647 DOI: 10.1085/Jgp.200308996  0.439
2003 Hwang TC, Koeppe RE, Andersen OS. Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics. Biochemistry. 42: 13646-58. PMID 14622011 DOI: 10.1021/Bi034887Y  0.424
2003 Koeppe RE, Sun H, van der Wel PC, Scherer EM, Pulay P, Greathouse DV. Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations. Journal of the American Chemical Society. 125: 12268-76. PMID 14519012 DOI: 10.1021/Ja035052D  0.704
2003 Lindholm-Sethson B, Nyström J, Geladi P, Koeppe R, Nelson A, Whitehouse C. Are biosensor arrays in one membrane possible? A combination of multifrequency impedance measurements and chemometrics. Analytical and Bioanalytical Chemistry. 377: 478-85. PMID 12920497 DOI: 10.1007/S00216-003-2103-Y  0.349
2003 de Planque MR, Bonev BB, Demmers JA, Greathouse DV, Koeppe RE, Separovic F, Watts A, Killian JA. Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions. Biochemistry. 42: 5341-8. PMID 12731875 DOI: 10.1021/Bi027000R  0.418
2003 Goforth RL, Chi AK, Greathouse DV, Providence LL, Koeppe RE, Andersen OS. Hydrophobic coupling of lipid bilayer energetics to channel function. The Journal of General Physiology. 121: 477-93. PMID 12719487 DOI: 10.1085/Jgp.200308797  0.42
2003 Weiss TM, van der Wel PC, Killian JA, Koeppe RE, Huang HW. Hydrophobic mismatch between helices and lipid bilayers. Biophysical Journal. 84: 379-85. PMID 12524291 DOI: 10.1016/S0006-3495(03)74858-9  0.76
2002 van der Wel PC, Strandberg E, Killian JA, Koeppe RE. Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR. Biophysical Journal. 83: 1479-88. PMID 12202373 DOI: 10.1016/S0006-3495(02)73918-0  0.77
2002 Petrache HI, Zuckerman DM, Sachs JN, Antoinette Killian J, Koeppe RE, Woolf TB. Hydrophobic matching mechanism investigated by molecular dynamics simulations Langmuir. 18: 1340-1351. DOI: 10.1021/La011338P  0.496
2001 Demmers JA, van Duijn E, Haverkamp J, Greathouse DV, Koeppe RE, Heck AJ, Killian JA. Interfacial positioning and stability of transmembrane peptides in lipid bilayers studied by combining hydrogen/deuterium exchange and mass spectrometry. The Journal of Biological Chemistry. 276: 34501-8. PMID 11435420 DOI: 10.1074/Jbc.M101401200  0.469
2001 de Planque MR, Goormaghtigh E, Greathouse DV, Koeppe RE, Kruijtzer JA, Liskamp RM, de Kruijff B, Killian JA. Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation. Biochemistry. 40: 5000-10. PMID 11305916 DOI: 10.1021/Bi000804R  0.42
2001 Jude AR, Providence LL, Schmutzer SE, Shobana S, Greathouse DV, Andersen OS, Koeppe R. Peptide backbone chemistry and membrane channel function: effects of a single amide-to-ester replacement on gramicidin channel structure and function. Biochemistry. 40: 1460-72. PMID 11170474 DOI: 10.1021/Bi001562Y  0.409
2001 Saparov SM, Antonenko YN, Koeppe RE, Pohl P. Desformylgramicidin: a model channel with an extremely high water permeability. Biophysical Journal. 79: 2526-34. PMID 11053127 DOI: 10.1016/S0006-3495(00)76493-9  0.349
2000 van der Wel PC, Pott T, Morein S, Greathouse DV, Koeppe RE, Killian JA. Tryptophan-anchored transmembrane peptides promote formation of nonlamellar phases in phosphatidylethanolamine model membranes in a mismatch-dependent manner. Biochemistry. 39: 3124-33. PMID 10715134 DOI: 10.1021/Bi9922594  0.753
2000 Koeppe RE, Hatchett J, Jude AR, Providence LL, Andersen OS, Greathouse DV. Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels. Biochemistry. 39: 2235-42. PMID 10694389 DOI: 10.1021/Bi9920679  0.373
2000 Demmers JAA, Haverkamp J, Heck AJR, Koeppe RE, Killian JA. Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers Proceedings of the National Academy of Sciences. 97: 3189-3194. DOI: 10.1073/Pnas.97.7.3189  0.474
1999 Jude AR, Greathouse DV, Leister MC, Koeppe RE. Steric interactions of valines 1, 5, and 7 in [valine 5, D-alanine 8] gramicidin A channels. Biophysical Journal. 77: 1927-35. PMID 10512813 DOI: 10.1016/S0006-3495(99)77034-7  0.36
1999 Killian JA, Morein S, van der Wel PC, de Planque MR, Greathouse DV, Koeppe RE. Peptide influences on lipids. Novartis Foundation Symposium. 225: 170-83; discussion 1. PMID 10472055 DOI: 10.1002/9780470515716.Ch11  0.773
1999 Koeppe RE, Greathouse DV, Providence LL, Shobana S, Andersen OS. Design and characterization of gramicidin channels with side chain or backbone mutations. Novartis Foundation Symposium. 225: 44-55; discussion 55. PMID 10472047 DOI: 10.1002/9780470515716.Ch4  0.444
1999 de Planque MR, Kruijtzer JA, Liskamp RM, Marsh D, Greathouse DV, Koeppe RE, de Kruijff B, Killian JA. Different membrane anchoring positions of tryptophan and lysine in synthetic transmembrane alpha-helical peptides. The Journal of Biological Chemistry. 274: 20839-46. PMID 10409625 DOI: 10.1074/Jbc.274.30.20839  0.506
1999 Cross TA, Arseniev A, Cornell BA, Davis JH, Killian JA, Koeppe RE, Nicholson LK, Separovic F, Wallace BA. Gramicidin channel controversy--revisited. Nature Structural Biology. 6: 610-1; discussion 61. PMID 10404210 DOI: 10.1038/10650  0.304
1999 Andersen OS, Apell HJ, Bamberg E, Busath DD, Koeppe RE, Sigworth FJ, Szabo G, Urry DW, Woolley A. Gramicidin channel controversy--the structure in a lipid environment. Nature Structural Biology. 6: 609; discussion 611-. PMID 10404209 DOI: 10.1038/10648  0.407
1999 Greathouse DV, Koeppe RE, Providence LL, Shobana S, Andersen OS. Design and characterization of gramicidin channels. Methods in Enzymology. 294: 525-50. PMID 9916247 DOI: 10.1016/S0076-6879(99)94031-4  0.407
1999 Andersen OS, Nielsen C, Maer AM, Lundbaek JA, Goulian M, Koeppe RE. Ion channels as tools to monitor lipid bilayer-membrane protein interactions: gramicidin channels as molecular force transducers. Methods in Enzymology. 294: 208-24. PMID 9916229 DOI: 10.1016/S0076-6879(99)94013-2  0.424
1999 Jude AR, Greathouse DV, Koeppe RE, Providence LL, Andersen OS. Modulation of gramicidin channel structure and function by the aliphatic "spacer" residues 10, 12, and 14 between the tryptophans. Biochemistry. 38: 1030-9. PMID 9893999 DOI: 10.1021/Bi982043M  0.366
1998 de Planque MR, Greathouse DV, Koeppe RE, Schäfer H, Marsh D, Killian JA. Influence of lipid/peptide hydrophobic mismatch on the thickness of diacylphosphatidylcholine bilayers. A 2H NMR and ESR study using designed transmembrane alpha-helical peptides and gramicidin A. Biochemistry. 37: 9333-45. PMID 9649314 DOI: 10.1021/Bi980233R  0.496
1998 Antoinette Killain J, de Planque MRR, van der Wel PCA, Salemink I, de Kruijff B, Greathouse DV, Koeppe RE. Modulation of membrane structure and function by hydrophobic mismatch between proteins and lipids Pure and Applied Chemistry. 70: 75-82. DOI: 10.1351/Pac199870010075  0.475
1998 Andersen OS, Greathouse DV, Providence LL, Becker MD, Koeppe RE. Importance of tryptophan dipoles for protein function: F-fluorination of tryptophans in gramicidin a channels Journal of the American Chemical Society. 120: 5142-5146. DOI: 10.1021/Ja980182L  0.416
1997 Morein S, Strandberg E, Killian JA, Persson S, Arvidson G, Koeppe RE, Lindblom G. Influence of membrane-spanning alpha-helical peptides on the phase behavior of the dioleoylphosphatidylcholine/water system. Biophysical Journal. 73: 3078-88. PMID 9414221 DOI: 10.1016/S0006-3495(97)78335-8  0.319
1997 Girshman J, Greathouse DV, Koeppe RE, Andersen OS. Gramicidin channels in phospholipid bilayers with unsaturated acyl chains. Biophysical Journal. 73: 1310-9. PMID 9284299 DOI: 10.1016/S0006-3495(97)78164-5  0.426
1996 Koeppe RE, Andersen OS. Engineering the gramicidin channel Annual Review of Biophysics and Biomolecular Structure. 25: 231-258. PMID 8800470 DOI: 10.1146/Annurev.Bb.25.060196.001311  0.408
1996 Koeppe RE, Vogt TC, Greathouse DV, Killian JA, de Kruijff B. Conformation of the acylation site of palmitoylgramicidin in lipid bilayers of dimyristoylphosphatidylcholine. Biochemistry. 35: 3641-8. PMID 8639517 DOI: 10.1021/Bi952046O  0.364
1996 Killian JA, Salemink I, de Planque MR, Lindblom G, Koeppe RE, Greathouse DV. Induction of nonbilayer structures in diacylphosphatidylcholine model membranes by transmembrane alpha-helical peptides: importance of hydrophobic mismatch and proposed role of tryptophans. Biochemistry. 35: 1037-45. PMID 8547239 DOI: 10.1021/Bi9519258  0.499
1995 Providence LL, Andersen OS, Greathouse DV, Koeppe RE, Bittman R. Gramicidin channel function does not depend on phospholipid chirality. Biochemistry. 34: 16404-11. PMID 8845367 DOI: 10.1021/Bi00050A022  0.415
1995 Koeppe RE, Killian JA, Vogt TC, de Kruijff B, Taylor MJ, Mattice GL, Greathouse DV. Palmitoylation-induced conformational changes of specific side chains in the gramicidin transmembrane channel. Biochemistry. 34: 9299-306. PMID 7542918 DOI: 10.1021/Bi00029A004  0.446
1995 Oiki S, Koeppe RE, Andersen OS. Voltage-dependent gating of an asymmetric gramicidin channel. Proceedings of the National Academy of Sciences of the United States of America. 92: 2121-5. PMID 7534411 DOI: 10.1073/Pnas.92.6.2121  0.349
1994 Oiki S, Koeppe RE, Andersen OS. Asymmetric gramicidin channels: heterodimeric channels with a single F6Val1 residue. Biophysical Journal. 66: 1823-32. PMID 7521224 DOI: 10.1016/S0006-3495(94)80976-2  0.371
1994 Greathouse DV, Hinton JF, Kim KS, Koeppe RE. Gramicidin A/short-chain phospholipid dispersions: chain length dependence of gramicidin conformation and lipid organization. Biochemistry. 33: 4291-9. PMID 7512381 DOI: 10.1021/Bi00180A025  0.368
1994 He K, Ludtke SJ, Wu Y, Huang HW, Andersen OS, Greathouse D, Koeppe RE. Closed state of gramicidin channel detected by X-ray in-plane scattering. Biophysical Chemistry. 49: 83-9. PMID 7510532 DOI: 10.1016/0301-4622(93)E0085-J  0.389
1994 Koeppe RE, Killian JA, Greathouse DV. Orientations of the tryptophan 9 and 11 side chains of the gramicidin channel based on deuterium nuclear magnetic resonance spectroscopy. Biophysical Journal. 66: 14-24. PMID 7510525 DOI: 10.1016/S0006-3495(94)80748-9  0.393
1993 Durkin JT, Providence LL, Koeppe RE, Andersen OS. Energetics of heterodimer formation among gramicidin analogues with an NH2-terminal addition or deletion. Consequences of missing a residue at the join in the channel. Journal of Molecular Biology. 231: 1102-21. PMID 7685829 DOI: 10.1006/Jmbi.1993.1355  0.396
1992 Williams LP, Narcessian EJ, Andersen OS, Waller GR, Taylor MJ, Lazenby JP, Hinton JF, Koeppe RE. Molecular and channel-forming characteristics of gramicidin K's: a family of naturally occurring acylated gramicidins. Biochemistry. 31: 7311-9. PMID 1380823  0.327
1992 Oiki S, Koeppe RE, Andersen OS. A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels. Biophysical Journal. 62: 28-30. PMID 1376169 DOI: 10.1016/S0006-3495(92)81768-X  0.333
1992 Becker MD, Koeppe RE, Andersen OS. Amino acid substitutions and ion channel function. Model-dependent conclusions. Biophysical Journal. 62: 25-7. PMID 1376168 DOI: 10.1016/S0006-3495(92)81767-8  0.353
1992 Durkin JT, Providence LL, Koeppe RE, Andersen OS. Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues. Biophysical Journal. 62: 145-57; discussion 1. PMID 1376164 DOI: 10.1016/S0006-3495(92)81801-5  0.351
1992 Koeppe RE, Providence LL, Greathouse DV, Heitz F, Trudelle Y, Purdie N, Andersen OS. On the helix sense of gramicidin A single channels. Proteins. 12: 49-62. PMID 1372741 DOI: 10.1002/Prot.340120107  0.337
1992 Cifu AS, Koeppe RE, Andersen OS. On the supramolecular organization of gramicidin channels. The elementary conducting unit is a dimer. Biophysical Journal. 61: 189-203. PMID 1371703 DOI: 10.1016/S0006-3495(92)81826-X  0.351
1992 Killian JA, Taylor MJ, Koeppe RE. Orientation of the valine-1 side chain of the gramicidin transmembrane channel and implications for channel functioning. A 2H NMR study. Biochemistry. 31: 11283-90. PMID 1280159 DOI: 10.1021/Bi00161A004  0.387
1992 Andersen OS, Koeppe RE. Molecular determinants of channel function. Physiological Reviews. 72: S89-158. PMID 1279736 DOI: 10.1152/Physrev.1992.72.Suppl_4.S89  0.366
1991 Becker MD, Greathouse DV, Koeppe RE, Andersen OS. Amino acid sequence modulation of gramicidin channel function: effects of tryptophan-to-phenylalanine substitutions on the single-channel conductance and duration. Biochemistry. 30: 8830-9. PMID 1716152 DOI: 10.1021/Bi00100A015  0.401
1991 Teng Q, Koeppe RE, Scarlata SF. Effect of salt and membrane fluidity on fluorophore motions of a gramicidin C derivative. Biochemistry. 30: 7984-90. PMID 1714298 DOI: 10.1021/Bi00246A016  0.457
1990 O'Connell AM, Koeppe RE, Andersen OS. Kinetics of gramicidin channel formation in lipid bilayers: transmembrane monomer association. Science (New York, N.Y.). 250: 1256-9. PMID 1700867 DOI: 10.1126/Science.1700867  0.407
1990 Sawyer DB, Koeppe RE, Andersen OS. Gramicidin single-channel properties show no solvent-history dependence. Biophysical Journal. 57: 515-23. PMID 1689593 DOI: 10.1016/S0006-3495(90)82567-4  0.372
1990 Koeppe RE, Mazet JL, Andersen OS. Distinction between dipolar and inductive effects in modulating the conductance of gramicidin channels. Biochemistry. 29: 512-20. PMID 1689177 DOI: 10.1021/Bi00454A027  0.396
1990 Durkin JT, Koeppe RE, Andersen OS. Energetics of gramicidin hybrid channel formation as a test for structural equivalence. Side-chain substitutions in the native sequence. Journal of Molecular Biology. 211: 221-34. PMID 1688951 DOI: 10.1016/0022-2836(90)90022-E  0.422
1989 Sawyer DB, Koeppe RE, Andersen OS. Induction of conductance heterogeneity in gramicidin channels. Biochemistry. 28: 6571-83. PMID 2477060 DOI: 10.1021/Bi00442A007  0.323
1989 Rottenberg H, Koeppe RE. Stimulation of cation transport in mitochondria by gramicidin and truncated derivatives. Biochemistry. 28: 4361-7. PMID 2475166 DOI: 10.1021/Bi00436A036  0.336
1989 Rottenberg H, Koeppe RE. Mechanism of uncoupling of oxidative phosphorylation by gramicidin. Biochemistry. 28: 4355-60. PMID 2475165 DOI: 10.1021/Bi00436A035  0.356
1987 Busath DD, Andersen OS, Koeppe RE. On the conductance heterogeneity in membrane channels formed by gramicidin A. A cooperative study. Biophysical Journal. 51: 79-88. PMID 2432954 DOI: 10.1016/S0006-3495(87)83313-1  0.387
1986 Durkin JT, Andersen OS, Blout ER, Heitz F, Koeppe RE, Trudelle Y. Structural information from functional measurements: single-channel studies on gramicidin analogues. Biophysical Journal. 49: 118-21. PMID 19431612 DOI: 10.1016/S0006-3495(86)83618-9  0.301
1986 Shungu DC, Hinton JF, Koeppe RE, Millett FS. Investigation of the interaction between thallous ions and gramicidin A in dimyristoylphosphatidylcholine vesicles: a thallium-205 NMR equilibrium study. Biochemistry. 25: 6103-8. PMID 2431708 DOI: 10.1021/Bi00368A040  0.378
1985 Koeppe RE, Haw JH, Paczkowski JA. On the recovery of Cys-containing peptides during peptide mapping by HPLC. Tryptic peptides of Trp-tRNA synthetase of E.coli. Febs Letters. 183: 313-6. PMID 3886424 DOI: 10.1016/0014-5793(85)80800-0  0.405
1985 Weiss LB, Koeppe RE. Semisynthesis of linear gramicidins using diphenyl phosphorazidate (DPPA). International Journal of Peptide and Protein Research. 26: 305-10. PMID 2414241 DOI: 10.1111/J.1399-3011.1985.Tb03209.X  0.304
1985 Koeppe RE, Paczkowski JA, Whaley WL. Gramicidin K, a new linear channel-forming gramicidin from Bacillus brevis Biochemistry. 24: 2822-2826. PMID 2410016 DOI: 10.1021/Bi00333A002  0.348
1984 Koeppe RE, Kimura M. Computer building of β-helical polypeptide models Biopolymers. 23: 23-38. DOI: 10.1002/Bip.360230104  0.316
1983 Turner GL, Hinton JF, Koeppe RE, Parli JA, Millett FS. Difference in association of Tl(I) with gramicidin A and gramicidin B in trifluoroethanol determined by Tl-205 NMR Bba - General Subjects. 756: 133-137. DOI: 10.1016/0304-4165(83)90083-1  0.322
1979 Koeppe RE, Berg JM, Hodgson KO, Stryer L. Gramicidin A crystals contain two cation binding sites per channel. Nature. 279: 723-5. PMID 88018 DOI: 10.1038/279723A0  0.637
1978 Koeppe RE, Hodgson KO, Stryer L. Helical channels in crystals of gramicidin A and of a cesium--gramicidin A complex: an x-ray diffraction study. Journal of Molecular Biology. 121: 41-54. PMID 77905 DOI: 10.1016/0022-2836(78)90261-9  0.566
1977 Koeppe RE, Krieger M, Stroud RM. The effect of pre-incubation on trypsin kinetics at low pH. Biochimica Et Biophysica Acta. 481: 617-21. PMID 15615 DOI: 10.1016/0005-2744(77)90294-7  0.571
1976 Koeppe RE, Stroud RM. A pulsed diffusion technique for the growth of protein crystals for x-ray diffraction. Journal of Molecular Biology. 98: 155-60. PMID 1195375 DOI: 10.1016/S0022-2836(75)80106-9  0.423
1976 Koeppe RE, Stroud RM. Mechanism of hydrolysis by serine proteases: direct determination of the pKa's of aspartyl-102 and aspartyl-194 in bovine trypsin using difference infrared spectroscopy. Biochemistry. 15: 3450-8. PMID 986162 DOI: 10.1021/Bi00661A009  0.488
1976 Krieger M, Koeppe RE, Stroud RM. pH dependence of tritium exchange with the C-2 protons of the histidines in bovine trypsin. Biochemistry. 15: 3458-64. PMID 8090 DOI: 10.1021/Bi00661A010  0.597
Show low-probability matches.