Year |
Citation |
Score |
2019 |
Krucinska J, Falcone E, Erlandsen H, Hazeen A, Lombardo MN, Estrada A, Robinson VL, Anderson A, Wright DL. Structural and Functional Studies of Bacterial Enolase, a Potential Target Against Gram-Negative Pathogens. Biochemistry. PMID 30714720 DOI: 10.1021/Acs.Biochem.8B01298 |
0.623 |
|
2017 |
Cammarata M, Thyer R, Lombardo M, Anderson A, Wright D, Ellington A, Brodbelt JS. Characterization of trimethoprim resistant dihydrofolate reductase mutants by mass spectrometry and inhibition by propargyl-linked antifolates. Chemical Science. 8: 4062-4072. PMID 29967675 DOI: 10.1039/C6Sc05235E |
0.654 |
|
2017 |
Hoody J, Alverson JB, Keshipeddy S, Barney PA, Walker L, Anderson AC, Wright DL, Priestley ND. Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1051: 54-59. PMID 28314188 DOI: 10.1016/J.Jchromb.2017.02.026 |
0.632 |
|
2017 |
Ojewole A, Lowegard A, Gainza P, Reeve SM, Georgiev I, Anderson AC, Donald BR. OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design. Methods in Molecular Biology (Clifton, N.J.). 1529: 291-306. PMID 27914058 DOI: 10.1007/978-1-4939-6637-0_15 |
0.779 |
|
2016 |
G-Dayanandan N, Scocchera EW, Keshipeddy S, Jones HF, Anderson AC, Wright DL. Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks. Organic Letters. PMID 27959567 DOI: 10.1021/Acs.Orglett.6B03438 |
0.559 |
|
2016 |
Reeve SM, Scocchera EW, G-Dayanadan N, Keshipeddy S, Krucinska J, Hajian B, Ferreira J, Nailor M, Aeschlimann J, Wright DL, Anderson AC. MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates. Cell Chemical Biology. PMID 27939900 DOI: 10.1016/J.Chembiol.2016.11.007 |
0.8 |
|
2016 |
Li J, Falcone ER, Holstein SA, Anderson AC, Wright DL, Wiemer AJ. Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis. Pharmacological Research. PMID 27663262 DOI: 10.1016/J.Phrs.2016.09.020 |
0.581 |
|
2016 |
Lombardo MN, G-Dayanandan N, Wright DL, Anderson AC. Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates. Acs Infectious Diseases. 2: 149-56. PMID 27624966 DOI: 10.1021/Acsinfecdis.5B00129 |
0.695 |
|
2016 |
Hajian B, Scocchera E, Keshipeddy S, G-Dayanandan N, Shoen C, Krucinska J, Reeve S, Cynamon M, Anderson AC, Wright DL. Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Plos One. 11: e0161740. PMID 27580226 DOI: 10.1371/Journal.Pone.0161740 |
0.819 |
|
2016 |
Scocchera E, Reeve SM, Keshipeddy S, Lombardo MN, Hajian B, Sochia AE, Alverson JB, Priestley ND, Anderson AC, Wright DL. Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens. Acs Medicinal Chemistry Letters. 7: 692-6. PMID 27437079 DOI: 10.1021/Acsmedchemlett.6B00120 |
0.796 |
|
2016 |
Estrada A, Wright DL, Anderson AC. Antibacterial Antifolates: From Development through Resistance to the Next Generation. Cold Spring Harbor Perspectives in Medicine. PMID 27352799 DOI: 10.1101/Cshperspect.A028324 |
0.66 |
|
2016 |
Reeve SM, Scocchera E, Ferreira J, G-Dayanandan N, Keshipeddy S, Wright DL, Anderson AC. Charged propargyl-linked antifolates reveal mechanisms of antifolate resistance and inhibit trimethoprim-resistant MRSA strains possessing clinically relevant mutations. Journal of Medicinal Chemistry. PMID 27308944 DOI: 10.1021/Acs.Jmedchem.6B00688 |
0.833 |
|
2016 |
Lombardo MN, G-Dayanandan N, Wright DL, Anderson AC. Crystal structures of the resistance-conferring dfrA1 reveal that propargyl-linked antifolates are potent inhibitors Acs Infectious Diseases. 149-156. DOI: 10.2210/Pdb5Ecx/Pdb |
0.682 |
|
2015 |
Anderson AC, Wright DL. The challenge of resistance in antimicrobial drug development. Future Microbiology. 10: 1709-10. PMID 26597424 DOI: 10.2217/Fmb.15.75 |
0.67 |
|
2015 |
Reeve SM, Lombardo MN, Anderson AC. Understanding the structural mechanisms of antibiotic resistance sets the platform for new discovery. Future Microbiology. PMID 26516790 DOI: 10.2217/Fmb.15.78 |
0.805 |
|
2015 |
Keshipeddy S, Reeve SM, Anderson AC, Wright DL. Non-racemic Antifolates Stereo-selectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus. Journal of the American Chemical Society. PMID 26098608 DOI: 10.1021/Jacs.5B01442 |
0.833 |
|
2015 |
Heidari-Torkabadi H, Che T, Lombardo MN, Wright DL, Anderson AC, Carey PR. Measuring propargyl-linked drug populations inside bacterial cells, and their interaction with a dihydrofolate reductase target, by Raman microscopy. Biochemistry. 54: 2719-26. PMID 25871808 DOI: 10.1021/Acs.Biochem.5B00202 |
0.63 |
|
2015 |
Reeve SM, Gainza P, Frey KM, Georgiev I, Donald BR, Anderson AC. Protein design algorithms predict viable resistance to an experimental antifolate. Proceedings of the National Academy of Sciences of the United States of America. 112: 749-54. PMID 25552560 DOI: 10.1073/Pnas.1411548112 |
0.807 |
|
2015 |
Chopra A, Anderson A, Rosenberg D, Giardina C. Abstract 3781: Effects of a novel microtubule inhibitor, AK301 on Apc heterozygote colon cells Cancer Research. 75: 3781-3781. DOI: 10.1158/1538-7445.Am2015-3781 |
0.31 |
|
2014 |
Lamb KM, Lombardo MN, Alverson J, Priestley ND, Wright DL, Anderson AC. Crystal structures of Klebsiella pneumoniae dihydrofolate reductase bound to propargyl-linked antifolates reveal features for potency and selectivity. Antimicrobial Agents and Chemotherapy. 58: 7484-91. PMID 25288083 DOI: 10.1128/Aac.03555-14 |
0.685 |
|
2014 |
Anderson AC, Wright DL. Antifolate agents: a patent review (2010 - 2013). Expert Opinion On Therapeutic Patents. 24: 687-97. PMID 24655343 DOI: 10.1517/13543776.2014.898062 |
0.582 |
|
2014 |
Ononye SN, Vanheyst MD, Giardina C, Wright DL, Anderson AC. Studies on the antiproliferative effects of tropolone derivatives in Jurkat T-lymphocyte cells. Bioorganic & Medicinal Chemistry. 22: 2188-93. PMID 24613456 DOI: 10.1016/J.Bmc.2014.02.018 |
0.782 |
|
2014 |
G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC. Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata. Journal of Medicinal Chemistry. 57: 2643-56. PMID 24568657 DOI: 10.1021/Jm401916J |
0.782 |
|
2014 |
Chopra A, Anderson A, Giardina C. Novel piperazine-based compounds inhibit microtubule dynamics and sensitize colon cancer cells to tumor necrosis factor-induced apoptosis. The Journal of Biological Chemistry. 289: 2978-91. PMID 24338023 DOI: 10.1074/Jbc.M113.499319 |
0.37 |
|
2013 |
Ononye SN, VanHeyst MD, Oblak EZ, Zhou W, Ammar M, Anderson AC, Wright DL. Tropolones as lead-like natural products: the development of potent and selective histone deacetylase inhibitors. Acs Medicinal Chemistry Letters. 4: 757-61. PMID 24900743 DOI: 10.1021/Ml400158K |
0.799 |
|
2013 |
Lamb KM, G-Dayanandan N, Wright DL, Anderson AC. Elucidating features that drive the design of selective antifolates using crystal structures of human dihydrofolate reductase. Biochemistry. 52: 7318-26. PMID 24053334 DOI: 10.1021/Bi400852H |
0.659 |
|
2013 |
Paulsen JL, Viswanathan K, Wright DL, Anderson AC. Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species. Bioorganic & Medicinal Chemistry Letters. 23: 1279-84. PMID 23375226 DOI: 10.1016/J.Bmcl.2013.01.008 |
0.786 |
|
2013 |
Zhou W, Scocchera EW, Wright DL, Anderson AC. Antifolates as effective antimicrobial agents: New generations of trimethoprim analogs Medchemcomm. 4: 908-915. DOI: 10.1039/C3Md00104K |
0.68 |
|
2012 |
Ononye SN, van Heyst M, Falcone EM, Anderson AC, Wright DL. Toward isozyme-selective inhibitors of histone deacetylase as therapeutic agents for the treatment of cancer. Pharmaceutical Patent Analyst. 1: 207-21. PMID 24163736 DOI: 10.4155/Ppa.12.21 |
0.791 |
|
2012 |
Viswanathan K, Ononye SN, Cooper HD, Kyle Hadden M, Anderson AC, Wright DL. Viridin analogs derived from steroidal building blocks. Bioorganic & Medicinal Chemistry Letters. 22: 6919-22. PMID 23040731 DOI: 10.1016/J.Bmcl.2012.09.015 |
0.773 |
|
2012 |
Zhou W, Viswanathan K, Hill D, Anderson AC, Wright DL. Acetylenic linkers in lead compounds: a study of the stability of the propargyl-linked antifolates. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 2002-8. PMID 22815313 DOI: 10.1124/Dmd.112.046870 |
0.646 |
|
2012 |
Frey KM, Viswanathan K, Wright DL, Anderson AC. Prospective screening of novel antibacterial inhibitors of dihydrofolate reductase for mutational resistance. Antimicrobial Agents and Chemotherapy. 56: 3556-62. PMID 22491688 DOI: 10.1128/Aac.06263-11 |
0.804 |
|
2012 |
Viswanathan K, Frey KM, Scocchera EW, Martin BD, Swain Iii PW, Alverson JB, Priestley ND, Anderson AC, Wright DL. Toward new therapeutics for skin and soft tissue infections: propargyl-linked antifolates are potent inhibitors of MRSA and Streptococcus pyogenes. Plos One. 7: e29434. PMID 22347365 DOI: 10.1371/Journal.Pone.0029434 |
0.781 |
|
2012 |
Anderson AC. Structure-based functional design of drugs: from target to lead compound. Methods in Molecular Biology (Clifton, N.J.). 823: 359-66. PMID 22081357 DOI: 10.1007/978-1-60327-216-2_23 |
0.399 |
|
2012 |
Anderson AC. Winning the arms race by improving drug discovery against mutating targets. Acs Chemical Biology. 7: 278-88. PMID 22050347 DOI: 10.1021/Cb200394T |
0.459 |
|
2011 |
Beierlein JM, Anderson AC. New developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis. Current Medicinal Chemistry. 18: 5083-94. PMID 22050756 DOI: 10.2174/092986711797636036 |
0.794 |
|
2011 |
Anderson AC, Pollastri MP, Schiffer CA, Peet NP. The challenge of developing robust drugs to overcome resistance. Drug Discovery Today. 16: 755-61. PMID 21784168 DOI: 10.1016/J.Drudis.2011.07.001 |
0.5 |
|
2011 |
Paulsen JL, Bendel SD, Anderson AC. Crystal structures of Candida albicans dihydrofolate reductase bound to propargyl-linked antifolates reveal the flexibility of active site loop residues critical for ligand potency and selectivity. Chemical Biology & Drug Design. 78: 505-12. PMID 21726415 DOI: 10.1111/J.1747-0285.2011.01169.X |
0.737 |
|
2011 |
Wright DL, Anderson AC. Antifolate agents: a patent review (2006 - 2010). Expert Opinion On Therapeutic Patents. 21: 1293-308. PMID 21619471 DOI: 10.1517/13543776.2011.587804 |
0.644 |
|
2011 |
Algul O, Paulsen JL, Anderson AC. 2,4-Diamino-5-(2'-arylpropargyl)pyrimidine derivatives as new nonclassical antifolates for human dihydrofolate reductase inhibition. Journal of Molecular Graphics & Modelling. 29: 608-13. PMID 21146434 DOI: 10.1016/J.Jmgm.2010.11.004 |
0.756 |
|
2010 |
Beierlein JM, Karri NG, Anderson AC. Targeted mutations of Bacillus anthracis dihydrofolate reductase condense complex structure−activity relationships. Journal of Medicinal Chemistry. 53: 7327-36. PMID 20882962 DOI: 10.1021/Jm100727T |
0.829 |
|
2010 |
Frey KM, Georgiev I, Donald BR, Anderson AC. Predicting resistance mutations using protein design algorithms. Proceedings of the National Academy of Sciences of the United States of America. 107: 13707-12. PMID 20643959 DOI: 10.1073/Pnas.1002162107 |
0.734 |
|
2010 |
Frey KM, Lombardo MN, Wright DL, Anderson AC. Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase. Journal of Structural Biology. 170: 93-7. PMID 20026215 DOI: 10.1016/J.Jsb.2009.12.011 |
0.788 |
|
2010 |
Zhang Y, Oblak EZ, Bolstad ESD, Anderson AC, Jasinski JP, Butcher RJ, Wright DL. Synthetic and computational studies on liphagal: A natural product inhibitor of PI-3K Tetrahedron Letters. 51: 6120-6122. DOI: 10.1016/J.Tetlet.2010.09.058 |
0.643 |
|
2009 |
Paulsen JL, Anderson AC. Scoring ensembles of docked protein:ligand interactions for virtual lead optimization. Journal of Chemical Information and Modeling. 49: 2813-9. PMID 19950979 DOI: 10.1021/Ci9003078 |
0.664 |
|
2009 |
Paulsen JL, Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC. In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans. Bioorganic & Medicinal Chemistry. 17: 4866-72. PMID 19560363 DOI: 10.1016/J.Bmc.2009.06.021 |
0.81 |
|
2009 |
Beierlein JM, Deshmukh L, Frey KM, Vinogradova O, Anderson AC. The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors. Biochemistry. 48: 4100-8. PMID 19323450 DOI: 10.1021/Bi802319W |
0.815 |
|
2009 |
Frey KM, Liu J, Lombardo MN, Bolstad DB, Wright DL, Anderson AC. Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. Journal of Molecular Biology. 387: 1298-308. PMID 19249312 DOI: 10.1016/J.Jmb.2009.02.045 |
0.817 |
|
2009 |
Chen CY, Georgiev I, Anderson AC, Donald BR. Computational structure-based redesign of enzyme activity. Proceedings of the National Academy of Sciences of the United States of America. 106: 3764-9. PMID 19228942 DOI: 10.1073/Pnas.0900266106 |
0.384 |
|
2009 |
Sundstrom TJ, Anderson AC, Wright DL. Inhibitors of phosphoinositide-3-kinase: a structure-based approach to understanding potency and selectivity. Organic & Biomolecular Chemistry. 7: 840-50. PMID 19225663 DOI: 10.1039/B819067B |
0.619 |
|
2009 |
Liu J, Bolstad DB, Bolstad ES, Wright DL, Anderson AC. Towards new antifolates targeting eukaryotic opportunistic infections. Eukaryotic Cell. 8: 483-6. PMID 19168759 DOI: 10.1128/Ec.00298-08 |
0.668 |
|
2009 |
Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC. Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors. Chemical Biology & Drug Design. 73: 62-74. PMID 19152636 DOI: 10.1111/J.1747-0285.2008.00745.X |
0.717 |
|
2009 |
Bolstad ES, Anderson AC. In pursuit of virtual lead optimization: pruning ensembles of receptor structures for increased efficiency and accuracy during docking. Proteins. 75: 62-74. PMID 18781587 DOI: 10.1002/Prot.22214 |
0.355 |
|
2009 |
deshmukh l, vinogradova o, beierlein j, frey k, anderson a. Solution structure of Bacillus anthracis dihydrofolate reductase Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kgk/Pdb |
0.757 |
|
2008 |
Bolstad DB, Bolstad ES, Wright DL, Anderson AC. Dihydrofolate reductase inhibitors: developments in antiparasitic chemotherapy. Expert Opinion On Therapeutic Patents. 18: 143-57. PMID 20553119 DOI: 10.1517/13543776.18.2.143 |
0.635 |
|
2008 |
Beierlein JM, Frey KM, Bolstad DB, Pelphrey PM, Joska TM, Smith AE, Priestley ND, Wright DL, Anderson AC. Synthetic and crystallographic studies of a new inhibitor series targeting Bacillus anthracis dihydrofolate reductase. Journal of Medicinal Chemistry. 51: 7532-40. PMID 19007108 DOI: 10.1021/Jm800776A |
0.815 |
|
2008 |
Blauvelt ML, Khalili M, Jaung W, Paulsen J, Anderson AC, Brian Wilson S, Howell AR. Alpha-S-GalCer: synthesis and evaluation for iNKT cell stimulation. Bioorganic & Medicinal Chemistry Letters. 18: 6374-6. PMID 18993065 DOI: 10.1016/J.Bmcl.2008.10.086 |
0.645 |
|
2008 |
Bolstad DB, Bolstad ES, Frey KM, Wright DL, Anderson AC. Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidium. Journal of Medicinal Chemistry. 51: 6839-52. PMID 18834108 DOI: 10.1021/Jm8009124 |
0.787 |
|
2008 |
Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC. Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase. Chemistry & Biology. 15: 990-6. PMID 18804036 DOI: 10.1016/J.Chembiol.2008.07.013 |
0.711 |
|
2008 |
Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins. 73: 889-901. PMID 18536013 DOI: 10.1002/Prot.22115 |
0.668 |
|
2008 |
Bolstad ES, Anderson AC. In pursuit of virtual lead optimization: the role of the receptor structure and ensembles in accurate docking. Proteins. 73: 566-80. PMID 18473360 DOI: 10.1002/Prot.22081 |
0.392 |
|
2007 |
Pelphrey PM, Popov VM, Joska TM, Beierlein JM, Bolstad ES, Fillingham YA, Wright DL, Anderson AC. Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis. Journal of Medicinal Chemistry. 50: 940-50. PMID 17269758 DOI: 10.1021/Jm061027H |
0.798 |
|
2007 |
Popov VM, Yee WA, Anderson AC. Towards in silico lead optimization: scores from ensembles of protein/ligand conformations reliably correlate with biological activity. Proteins. 66: 375-87. PMID 17078091 DOI: 10.1002/Prot.21201 |
0.404 |
|
2006 |
Stevens BW, Lilien RH, Georgiev I, Donald BR, Anderson AC. Redesigning the PheA domain of gramicidin synthetase leads to a new understanding of the enzyme's mechanism and selectivity. Biochemistry. 45: 15495-504. PMID 17176071 DOI: 10.1021/Bi061788M |
0.365 |
|
2006 |
Joska TM, Anderson AC. Structure-activity relationships of Bacillus cereus and Bacillus anthracis dihydrofolate reductase: toward the identification of new potent drug leads. Antimicrobial Agents and Chemotherapy. 50: 3435-43. PMID 17005826 DOI: 10.1128/Aac.00386-06 |
0.479 |
|
2006 |
Popov VM, Chan DC, Fillingham YA, Atom Yee W, Wright DL, Anderson AC. Analysis of complexes of inhibitors with Cryptosporidium hominis DHFR leads to a new trimethoprim derivative. Bioorganic & Medicinal Chemistry Letters. 16: 4366-70. PMID 16750361 DOI: 10.1016/J.Bmcl.2006.05.047 |
0.666 |
|
2006 |
Chan DC, Anderson AC. Towards species-specific antifolates. Current Medicinal Chemistry. 13: 377-98. PMID 16475929 |
0.323 |
|
2005 |
Anderson AC. Two crystal structures of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveal protein-ligand interactions including a structural basis for observed antifolate resistance. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 258-62. PMID 16511011 DOI: 10.1107/S1744309105002435 |
0.371 |
|
2005 |
Finer-Moore JS, Anderson AC, O'Neil RH, Costi MP, Ferrari S, Krucinski J, Stroud RM. The structure of Cryptococcus neoformans thymidylate synthase suggests strategies for using target dynamics for species-specific inhibition. Acta Crystallographica. Section D, Biological Crystallography. 61: 1320-34. PMID 16204883 DOI: 10.1107/S0907444905022638 |
0.495 |
|
2005 |
Couch RD, Browning RG, Honda T, Gribble GW, Wright DL, Sporn MB, Anderson AC. Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action. Bioorganic & Medicinal Chemistry Letters. 15: 2215-9. PMID 15837296 DOI: 10.1016/J.Bmcl.2005.03.031 |
0.564 |
|
2003 |
O'Neil RH, Lilien RH, Donald BR, Stroud RM, Anderson AC. The crystal structure of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveals a novel architecture for the bifunctional enzyme. The Journal of Eukaryotic Microbiology. 50: 555-6. PMID 14736160 DOI: 10.1111/J.1550-7408.2003.Tb00627.X |
0.529 |
|
2003 |
O'Neil RH, Lilien RH, Donald BR, Stroud RM, Anderson AC. Phylogenetic classification of protozoa based on the structure of the linker domain in the bifunctional enzyme, dihydrofolate reductase-thymidylate synthase. The Journal of Biological Chemistry. 278: 52980-7. PMID 14555647 DOI: 10.1074/Jbc.M310328200 |
0.539 |
|
2001 |
Anderson AC, O'Neil RH, Surti TS, Stroud RM. Approaches to solving the rigid receptor problem by identifying a minimal set of flexible residues during ligand docking. Chemistry & Biology. 8: 445-57. PMID 11358692 DOI: 10.1016/S1074-5521(01)00023-0 |
0.585 |
|
2000 |
Anderson AC, Perry KM, Freymann DM, Stroud RM. The crystal structure of thymidylate synthase from Pneumocystis carinii reveals a fungal insert important for drug design. Journal of Molecular Biology. 297: 645-57. PMID 10731418 DOI: 10.1006/Jmbi.2000.3544 |
0.773 |
|
1999 |
Anderson AC, O'Neil RH, DeLano WL, Stroud RM. The structural mechanism for half-the-sites reactivity in an enzyme, thymidylate synthase, involves a relay of changes between subunits. Biochemistry. 38: 13829-36. PMID 10529228 DOI: 10.1021/Bi991610I |
0.566 |
|
1999 |
Anderson AC, O'Neil RH, Filman DJ, Frederick CA. Crystal structure of a brominated RNA helix with four mismatched base pairs: An investigation into RNA conformational variability. Biochemistry. 38: 12577-85. PMID 10504226 DOI: 10.1021/Bi9904508 |
0.645 |
|
1996 |
Anderson AC, Earp BE, Frederick CA. Sequence variation as a strategy for crystallizing RNA motifs. Journal of Molecular Biology. 259: 696-703. PMID 8683576 DOI: 10.1006/Jmbi.1996.0351 |
0.636 |
|
1996 |
Anderson AC, Scaringe SA, Earp BE, Frederick CA. HPLC purification of RNA for crystallography and NMR. Rna (New York, N.Y.). 2: 110-7. PMID 8601278 |
0.597 |
|
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