Zhengqi Wang, Ph.D. - Publications

Affiliations: 
2000 University of Notre Dame, Notre Dame, IN, United States 
Area:
Molecular Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang Z, Emmel G, Lim HS, Zhu W, Kosters A, Ghosn EEB, Qiu P, Bunting KD. Stromal STAT5-mediated trophic activity regulates hematopoietic niche factors. Stem Cells (Dayton, Ohio). PMID 37465968 DOI: 10.1093/stmcls/sxad055  0.317
2019 Wang Z, Vaughan TY, Zhu W, Chen Y, Fu G, Medrzycki M, Nishio H, Bunting ST, Hankey-Giblin PA, Nusrat A, Parkos CA, Wang D, Wen R, Bunting KD. Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8 T-Cell Activation. Frontiers in Immunology. 10: 486. PMID 30936879 DOI: 10.3389/Fimmu.2019.00486  0.369
2018 Mi T, Wang Z, Bunting KD. The Cooperative Relationship between STAT5 and Reactive Oxygen Species in Leukemia: Mechanism and Therapeutic Potential. Cancers. 10. PMID 30262727 DOI: 10.3390/Cancers10100359  0.38
2018 Lee JA, Wang Z, Sambo D, Bunting KD, Pallas DC. Global loss of Leucine Carboxyl Methyltransferase-1 causes severe defects in fetal liver hematopoiesis. The Journal of Biological Chemistry. PMID 29735529 DOI: 10.1074/Jbc.Ra118.002012  0.403
2017 Metts J, Bradley HL, Wang Z, Shah NP, Kapur R, Arbiser JL, Bunting KD. Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells. Scientific Reports. 7: 4447. PMID 28667329 DOI: 10.1038/S41598-017-04796-1  0.371
2017 Wang Z, Bunting KD. Stat5 deficiency decreases transcriptional heterogeneity and supports emergence of hematopoietic sub-populations. Oncotarget. PMID 28390194 DOI: 10.18632/Oncotarget.15236  0.442
2016 Wang Z, Bunting KD. STAT5 activation in B-cell acute lymphoblastic leukemia: damned if you do, damned if you don't. Cancer Cell & Microenvironment. 3. PMID 26973852 DOI: 10.14800/Ccm.1186  0.447
2015 Wang Z, Medrzycki M, Bunting ST, Bunting KD. Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis. Oncotarget. 6: 28961-72. PMID 26338970 DOI: 10.18632/Oncotarget.5009  0.464
2015 Park J, Schlederer M, Schreiber M, Ice R, Merkel O, Bilban M, Hofbauer S, Kim S, Addison J, Zou J, Ji C, Bunting ST, Wang Z, Shoham M, Huang G, et al. AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis. Oncotarget. PMID 26079538 DOI: 10.18632/Oncotarget.4136  0.306
2014 Wang Z, Li G, Bunting KD. STAT5 N-domain deleted isoforms are naturally occurring hypomorphs partially rescued in hematopoiesis by transgenic Bcl-2 expression. American Journal of Blood Research. 4: 20-6. PMID 25232501  0.352
2014 Qing Y, Wang Z, Bunting KD, Gerson SL. Bcl2 overexpression rescues the hematopoietic stem cell defects in Ku70-deficient mice by restoration of quiescence. Blood. 123: 1002-11. PMID 24394664 DOI: 10.1182/Blood-2013-08-521716  0.402
2014 Vaughan-Whitley TY, Nishio H, Imhoff B, Wang Z, Bunting ST, Hankey-Giblin P, Nusrat A, Parkos CA, Bunting KD. Dysregulated Macrophage Pro-Inflammatory Cytokine Production and Chronic Colitis in Mice Lacking Both Gab2 and Gab3 Blood. 124: 457-457. DOI: 10.1182/Blood.V124.21.457.457  0.404
2013 Wang Z, Bunting KD. STAT5 in hematopoietic stem cell biology and transplantation. Jak-Stat. 2: e27159. PMID 24498540 DOI: 10.4161/jkst.27159  0.343
2012 Wang Z, Kang Z, Zhang Y, Tse W, Bunting KD. Mutation of STAT1/3 binding sites in gp130(FXXQ) knock-in mice does not alter hematopoietic stem cell repopulation or self-renewal potential. American Journal of Stem Cells. 1: 146-153. PMID 22754757  0.303
2012 Du J, Chen Y, Li Q, Han X, Cheng C, Wang Z, Danielpour D, Dunwoodie SL, Bunting KD, Yang YC. HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency. Blood. 119: 2789-98. PMID 22308296 DOI: 10.1182/Blood-2011-10-387902  0.419
2012 Pullen NA, Barnstein BO, Falanga YT, Wang Z, Suzuki R, Tamang TD, Khurana MC, Harry EA, Draber P, Bunting KD, Mizuno K, Wilson BS, Ryan JJ. Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production. The Journal of Biological Chemistry. 287: 2045-54. PMID 22130676 DOI: 10.1074/Jbc.M111.311142  0.413
2012 Wang Z, Li G, Kang Z, Vaughan TY, Bunting ST, Tse W, Bunting KD. STAT5 Promotes Hematopoietic Stem Cell Maintenance by Increasing Quiescence-Associated Gene Expression and Suppressing Lymphoid Commitment Blood. 120: 851-851. DOI: 10.1182/Blood.V120.21.851.851  0.388
2012 Qing Y, Wang Z, Matsuyama S, Bunting KD, Gerson SL. Rescue of the HSC Maintenance Defects in Ku70-Deficient Mice by Overexpression of Bcl2 Reveals a Novel Role of Bcl2 in HSC Blood. 120: 1235-1235. DOI: 10.1182/Blood.V120.21.1235.1235  0.426
2011 Liu Z, Yang A, Wang Z, Bunting KD, Davuluri G, Green MR, Devireddy LR. Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3. The Journal of Biological Chemistry. 286: 20606-14. PMID 21507940 DOI: 10.1182/Blood.V116.21.1560.1560  0.377
2011 Wang Z, Li G, Kang Z, Bunting ST, Tse W, Bunting KD. STAT5 Has Tumor Suppressor-Like Activity in a Murine Model of Myc-Initiated Acute B-Lymphoblastic Leukemia/Lymphoma Blood. 118: 919-919. DOI: 10.1182/Blood.V118.21.919.919  0.423
2011 Du J, Chen Y, Li Q, Wang Z, Dunwoodie S, Bunting KD, Yang Y. Cited2 Regulates Hematopoietic Stem Cell Quiescence Through HIF-1α Dependent and Independent Pathways Blood. 118: 912-912. DOI: 10.1182/Blood.V118.21.912.912  0.426
2011 Nivarthi H, Tsyrulnyk A, Warsch W, Wang Z, Winkler S, Kenner L, Müller M, Baum C, Bunting KD, Sexl V, Rülicke T, Moriggl R. Generation of a Transgenic Mouse with Inducible Constitutively Active Stat5a Blood. 118: 3399-3399. DOI: 10.1182/Blood.V118.21.3399.3399  0.456
2010 Li G, Miskimen KL, Wang Z, Xie XY, Tse W, Gouilleux F, Moriggl R, Bunting KD. Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin. Leukemia. 24: 1397-405. PMID 20535152 DOI: 10.1038/Leu.2010.131  0.444
2010 Li G, Wang Z, Miskimen KL, Zhang Y, Tse W, Bunting KD. Gab2 promotes hematopoietic stem cell maintenance and self-renewal synergistically with STAT5. Plos One. 5: e9152. PMID 20161778 DOI: 10.1371/Journal.Pone.0009152  0.434
2010 Li G, Miskimen KL, Wang Z, Xie XY, Brenzovich J, Ryan JJ, Tse W, Moriggl R, Bunting KD. STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease. Blood. 115: 1416-24. PMID 20008792 DOI: 10.1182/Blood-2009-07-234963  0.426
2009 Wang Z, Li G, Tse W, Bunting KD. Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement. Blood. 113: 4856-65. PMID 19258595 DOI: 10.1182/Blood-2008-09-181107  0.435
2009 Ohmori K, Luo Y, Jia Y, Nishida J, Wang Z, Bunting KD, Wang D, Huang H. IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. Journal of Immunology (Baltimore, Md. : 1950). 182: 2835-41. PMID 19234178 DOI: 10.4049/Jimmunol.0802870  0.304
2009 Li G, Wang Z, Miskimen KL, Xie XY, Tse W, Gouilleux F, Moriggl R, Bunting KD. Genetic and Pharmacologic Targeting of STAT5/Gab2/PI3K/mTOR Signaling in a Mouse Myeloproliferative Disease Model. Blood. 114: 3902-3902. DOI: 10.1182/Blood.V114.22.3902.3902  0.472
2009 Qing Y, Wang Z, Liu M, Bunting KD, Gerson SL. Regulation of Hematopoietic Stem Cell Quiescence by Ku70. Blood. 114: 3613-3613. DOI: 10.1182/Blood.V114.22.3613.3613  0.419
2008 Cohen PA, Koski GK, Czerniecki BJ, Bunting KD, Fu XY, Wang Z, Zhang WJ, Carter CS, Awad M, Distel CA, Nagem H, Paustian CC, Johnson TD, Tisdale JF, Shu S. STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood. 112: 1832-43. PMID 18577706 DOI: 10.1182/Blood-2007-12-130138  0.322
2008 Wang Z, Bunting KD. Hematopoietic stem cell transplant into non-myeloablated W/Wv mice to detect steady-state engraftment defects. Methods in Molecular Biology (Clifton, N.J.). 430: 171-81. PMID 18370299 DOI: 10.1007/978-1-59745-182-6_12  0.362
2008 Davis MC, McColl KS, Zhong F, Wang Z, Malone MH, Distelhorst CW. Dexamethasone-induced inositol 1,4,5-trisphosphate receptor elevation in murine lymphoma cells is not required for dexamethasone-mediated calcium elevation and apoptosis. The Journal of Biological Chemistry. 283: 10357-65. PMID 18272518 DOI: 10.1074/Jbc.M800269200  0.309
2008 Wang Z, Rong YP, Malone MH, Davis MC, Zhong F, Distelhorst CW. Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis (Oncogene (2006) 25, (1903-1913) DOI: 10.1038/sj.onc.1209218)) Oncogene. 27: 1342. DOI: 10.1038/Sj.Onc.1211001  0.354
2007 Li G, Wang Z, Zhang Y, Kang Z, Haviernikova E, Cui Y, Hennighausen L, Moriggl R, Wang D, Tse W, Bunting KD. STAT5 requires the N-domain to maintain hematopoietic stem cell repopulating function and appropriate lymphoid-myeloid lineage output. Experimental Hematology. 35: 1684-94. PMID 17976521 DOI: 10.1016/J.Exphem.2007.08.026  0.446
2007 Zhang Y, Diaz-Flores E, Li G, Wang Z, Kang Z, Haviernikova E, Rowe S, Qu CK, Tse W, Shannon KM, Bunting KD. Abnormal hematopoiesis in Gab2 mutant mice. Blood. 110: 116-24. PMID 17374739 DOI: 10.1182/Blood-2006-11-060707  0.438
2007 Li G, Wang Z, Zhang Y, Haviernikova E, Tse W, Bunting KD. Physiologically Significant Genetic Interaction between STAT5 and Gab2 during Normal and Pathologic Hematopoiesis. Blood. 110: 87-87. DOI: 10.1182/Blood.V110.11.87.87  0.398
2007 Wang Z, Li G, Haviernikova E, Tse W, Bunting KD. Conditional Deletion of STAT5 in Non-Myeloablated Recipient Mice Promotes Donor Hematopoietic Stem Cell Engraftment. Blood. 110: 178-178. DOI: 10.1182/Blood.V110.11.178.178  0.451
2006 Barnstein BO, Li G, Wang Z, Kennedy S, Chalfant C, Nakajima H, Bunting KD, Ryan JJ. Stat5 expression is required for IgE-mediated mast cell function. Journal of Immunology (Baltimore, Md. : 1950). 177: 3421-6. PMID 16920984 DOI: 10.4049/Jimmunol.177.5.3421  0.387
2006 Wang Z, Rong YP, Malone MH, Davis MC, Zhong F, Distelhorst CW. Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis. Oncogene. 25: 1903-13. PMID 16301999 DOI: 10.1038/Sj.Onc.1209218  0.416
2004 Malone MH, Wang Z, Distelhorst CW. The glucocorticoid-induced gene tdag8 encodes a pro-apoptotic G protein-coupled receptor whose activation promotes glucocorticoid-induced apoptosis. The Journal of Biological Chemistry. 279: 52850-9. PMID 15485889 DOI: 10.1074/Jbc.M408040200  0.383
2003 Wang Z, Malone MH, Thomenius MJ, Zhong F, Xu F, Distelhorst CW. Dexamethasone-induced gene 2 (dig2) is a novel pro-survival stress gene induced rapidly by diverse apoptotic signals. The Journal of Biological Chemistry. 278: 27053-8. PMID 12736248 DOI: 10.1074/Jbc.M303723200  0.386
2003 Wang Z, Malone MH, He H, McColl KS, Distelhorst CW. Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis. The Journal of Biological Chemistry. 278: 23861-7. PMID 12676946 DOI: 10.1074/Jbc.M301843200  0.4
2003 Thomenius MJ, Wang NS, Reineks EZ, Wang Z, Distelhorst CW. Bcl-2 on the endoplasmic reticulum regulates Bax activity by binding to BH3-only proteins. The Journal of Biological Chemistry. 278: 6243-50. PMID 12477729 DOI: 10.1074/Jbc.M208878200  0.316
2001 Suh E, Wang Z, Swain GP, Tenniswood M, Traber PG. Clusterin gene transcription is activated by caudal-related homeobox genes in intestinal epithelium. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G149-56. PMID 11123208 DOI: 10.1152/Ajpgi.2001.280.1.G149  0.564
1998 Tenniswood M, Wang Z, Lakins J, Morrissey C, O'Sullivan J, Tang H. Clusterin in the male reproductive tract Journal of Andrology. 19: 508. PMID 9796610 DOI: 10.1002/J.1939-4640.1998.Tb02052.X  0.497
Show low-probability matches.