Year |
Citation |
Score |
2018 |
Meshik X, O'Neill PR, Gautam N. Optogenetic Control of Cell Migration. Methods in Molecular Biology (Clifton, N.J.). 1749: 313-324. PMID 29526006 DOI: 10.1007/978-1-4939-7701-7_22 |
0.419 |
|
2016 |
O'Neill PR, Kalyanaraman V, Gautam N. Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration. Molecular Biology of the Cell. PMID 26941336 DOI: 10.1091/Mbc.E15-12-0832 |
0.327 |
|
2015 |
O'Neill PR, Gautam N. Optimizing optogenetic constructs for control over signaling and cell behaviours. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 14: 1578-85. PMID 26135203 DOI: 10.1039/C5Pp00171D |
0.324 |
|
2015 |
Karunarathne WK, O'Neill PR, Gautam N. Subcellular optogenetics - controlling signaling and single-cell behavior. Journal of Cell Science. 128: 15-25. PMID 25433038 DOI: 10.1242/Jcs.154435 |
0.383 |
|
2014 |
Giri L, Patel AK, Karunarathne WK, Kalyanaraman V, Venkatesh KV, Gautam N. A G-protein subunit translocation embedded network motif underlies GPCR regulation of calcium oscillations. Biophysical Journal. 107: 242-54. PMID 24988358 DOI: 10.1016/J.Bpj.2014.05.020 |
0.465 |
|
2014 |
O'Neill PR, Gautam N. Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration. Molecular Biology of the Cell. 25: 2305-14. PMID 24920824 DOI: 10.1091/Mbc.E14-04-0870 |
0.503 |
|
2014 |
O'Neill PR, Giri L, Karunarathne WK, Patel AK, Venkatesh KV, Gautam N. The structure of dynamic GPCR signaling networks. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 6: 115-23. PMID 24741711 DOI: 10.1002/Wsbm.1249 |
0.314 |
|
2013 |
Karunarathne WK, Giri L, Patel AK, Venkatesh KV, Gautam N. Optical control demonstrates switch-like PIP3 dynamics underlying the initiation of immune cell migration. Proceedings of the National Academy of Sciences of the United States of America. 110: E1575-83. PMID 23569254 DOI: 10.1073/Pnas.1220755110 |
0.338 |
|
2013 |
Karunarathne WK, Giri L, Kalyanaraman V, Gautam N. Optically triggering spatiotemporally confined GPCR activity in a cell and programming neurite initiation and extension. Proceedings of the National Academy of Sciences of the United States of America. 110: E1565-74. PMID 23479634 DOI: 10.1073/Pnas.1220697110 |
0.331 |
|
2012 |
O'Neill PR, Karunarathne WK, Kalyanaraman V, Silvius JR, Gautam N. G-protein signaling leverages subunit-dependent membrane affinity to differentially control βγ translocation to intracellular membranes. Proceedings of the National Academy of Sciences of the United States of America. 109: E3568-77. PMID 23213235 DOI: 10.1073/Pnas.1205345109 |
0.492 |
|
2012 |
Ajith Karunarathne WK, O'Neill PR, Martinez-Espinosa PL, Kalyanaraman V, Gautam N. All G protein βγ complexes are capable of translocation on receptor activation. Biochemical and Biophysical Research Communications. 421: 605-11. PMID 22538369 DOI: 10.1016/J.Bbrc.2012.04.054 |
0.563 |
|
2012 |
Gautam N. Real time analysis of protein location and function: a Golgi-specific PKD sensor. Biotechnology Journal. 7: 17-8. PMID 22057971 DOI: 10.1002/Biot.201100424 |
0.301 |
|
2011 |
Cho JH, Saini DK, Karunarathne WK, Kalyanaraman V, Gautam N. Alteration of Golgi structure in senescent cells and its regulation by a G protein γ subunit. Cellular Signalling. 23: 785-93. PMID 21238584 DOI: 10.1016/J.Cellsig.2011.01.001 |
0.522 |
|
2010 |
Saini DK, Karunarathne WK, Angaswamy N, Saini D, Cho JH, Kalyanaraman V, Gautam N. Regulation of Golgi structure and secretion by receptor-induced G protein βγ complex translocation. Proceedings of the National Academy of Sciences of the United States of America. 107: 11417-22. PMID 20534534 DOI: 10.1073/pnas.1003042107 |
0.397 |
|
2010 |
Saini DK, Gautam N. Live cell imaging for studying g protein-coupled receptor activation in single cells. Methods in Molecular Biology (Clifton, N.J.). 617: 191-207. PMID 20336424 DOI: 10.1007/978-1-60327-323-7_16 |
0.475 |
|
2009 |
Chisari M, Saini DK, Cho JH, Kalyanaraman V, Gautam N. G protein subunit dissociation and translocation regulate cellular response to receptor stimulation. Plos One. 4: e7797. PMID 19936219 DOI: 10.1371/Journal.Pone.0007797 |
0.536 |
|
2009 |
Saini DK, Chisari M, Gautam N. Shuttling and translocation of heterotrimeric G proteins and Ras. Trends in Pharmacological Sciences. 30: 278-86. PMID 19427041 DOI: 10.1016/J.Tips.2009.04.001 |
0.465 |
|
2007 |
Saini DK, Kalyanaraman V, Chisari M, Gautam N. A family of G protein βγ subunits translocate reversibly from the plasma membrane to endomembranes on receptor activation. The Journal of Biological Chemistry. 282: 24099-108. PMID 17581822 DOI: 10.1074/Jbc.M701191200 |
0.606 |
|
2007 |
Chisari M, Saini DK, Kalyanaraman V, Gautam N. Shuttling of G protein subunits between the plasma membrane and intracellular membranes. The Journal of Biological Chemistry. 282: 24092-8. PMID 17576765 DOI: 10.1074/Jbc.M704246200 |
0.478 |
|
2006 |
Akgoz M, Kalyanaraman V, Gautam N. G protein betagamma complex translocation from plasma membrane to Golgi complex is influenced by receptor gamma subunit interaction. Cellular Signalling. 18: 1758-68. PMID 16517125 DOI: 10.1016/J.Cellsig.2006.01.016 |
0.553 |
|
2006 |
Azpiazu I, Gautam N. A G protein gamma subunit peptide stabilizes a novel muscarinic receptor state. Biochemical and Biophysical Research Communications. 341: 904-10. PMID 16466691 DOI: 10.1016/J.Bbrc.2006.01.093 |
0.427 |
|
2006 |
Azpiazu I, Akgoz M, Kalyanaraman V, Gautam N. G protein betagamma11 complex translocation is induced by Gi, Gq and Gs coupling receptors and is regulated by the alpha subunit type. Cellular Signalling. 18: 1190-200. PMID 16242307 DOI: 10.1016/J.Cellsig.2005.09.007 |
0.538 |
|
2004 |
Akgoz M, Kalyanaraman V, Gautam N. Receptor-mediated reversible translocation of the G protein betagamma complex from the plasma membrane to the Golgi complex. The Journal of Biological Chemistry. 279: 51541-4. PMID 15448129 DOI: 10.1074/Jbc.M410639200 |
0.517 |
|
2004 |
Azpiazu I, Gautam N. A fluorescence resonance energy transfer-based sensor indicates that receptor access to a G protein is unrestricted in a living mammalian cell. The Journal of Biological Chemistry. 279: 27709-18. PMID 15078878 DOI: 10.1074/Jbc.M403712200 |
0.453 |
|
2003 |
Gautam N. A conformational switch regulates receptor-G protein interaction. Structure (London, England : 1993). 11: 359-60. PMID 12679009 DOI: 10.1016/S0969-2126(03)00054-6 |
0.515 |
|
2002 |
Akgoz M, Azpiazu I, Kalyanaraman V, Gautam N. Role of the G protein gamma subunit in beta gamma complex modulation of phospholipase Cbeta function. The Journal of Biological Chemistry. 277: 19573-8. PMID 11914377 DOI: 10.1074/Jbc.M201546200 |
0.516 |
|
2002 |
Hou Y, Chang V, Gautam N. Determining G protein heterotrimer formation. Methods in Enzymology. 344: 505-12. PMID 11771406 DOI: 10.1016/S0076-6879(02)44736-2 |
0.511 |
|
2002 |
Kale TA, Turek TC, Chang V, Gautam N, Distefano MD. Preparation and application of G protein gamma subunit-derived peptides incorporating a photoactive isoprenoid. Methods in Enzymology. 344: 245-58. PMID 11771387 DOI: 10.1016/S0076-6879(02)44719-2 |
0.49 |
|
2002 |
Azpiazu I, Gautam N. Role of G protein beta gamma complex in receptor-G protein interaction. Methods in Enzymology. 344: 112-25. PMID 11771376 DOI: 10.1016/S0076-6879(02)44709-X |
0.579 |
|
2001 |
Fogg VC, Azpiazu I, Linder ME, Smrcka A, Scarlata S, Gautam N. Role of the gamma subunit prenyl moiety in G protein beta gamma complex interaction with phospholipase Cbeta. The Journal of Biological Chemistry. 276: 41797-802. PMID 11546822 DOI: 10.1074/Jbc.M107661200 |
0.5 |
|
2001 |
Azpiazu I, Gautam N. G protein gamma subunit interaction with a receptor regulates receptor-stimulated nucleotide exchange. The Journal of Biological Chemistry. 276: 41742-7. PMID 11546799 DOI: 10.1074/Jbc.M104034200 |
0.582 |
|
2001 |
Hou Y, Chang V, Capper AB, Taussig R, Gautam N. G Protein beta subunit types differentially interact with a muscarinic receptor but not adenylyl cyclase type II or phospholipase C-beta 2/3. The Journal of Biological Chemistry. 276: 19982-8. PMID 11262394 DOI: 10.1074/Jbc.M010424200 |
0.473 |
|
2000 |
Hou Y, Azpiazu I, Smrcka A, Gautam N. Selective role of G protein gamma subunits in receptor interaction. The Journal of Biological Chemistry. 275: 38961-4. PMID 11042163 DOI: 10.1074/Jbc.C000604200 |
0.563 |
|
1999 |
Downes GB, Gautam N. The G protein subunit gene families. Genomics. 62: 544-52. PMID 10644457 DOI: 10.1006/Geno.1999.5992 |
0.767 |
|
1999 |
Azpiazu I, Cruzblanca H, Li P, Linder M, Zhuo M, Gautam N. A G protein gamma subunit-specific peptide inhibits muscarinic receptor signaling. The Journal of Biological Chemistry. 274: 35305-8. PMID 10585394 DOI: 10.1074/Jbc.274.50.35305 |
0.48 |
|
1999 |
Downes GB, Gilbert DJ, Copeland NG, Gautam N, Jenkins NA. Chromosomal mapping of five mouse G protein gamma subunits. Genomics. 57: 173-6. PMID 10191100 DOI: 10.1006/Geno.1999.5763 |
0.769 |
|
1999 |
Bell B, Xing H, Yan K, Gautam N, Muslin AJ. KSR-1 binds to G-protein betagamma subunits and inhibits beta gamma-induced mitogen-activated protein kinase activation. The Journal of Biological Chemistry. 274: 7982-6. PMID 10075696 DOI: 10.1074/Jbc.274.12.7982 |
0.506 |
|
1998 |
García DE, Li B, García-Ferreiro RE, Hernández-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, Hille B. G-protein beta-subunit specificity in the fast membrane-delimited inhibition of Ca2+ channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9163-70. PMID 9801356 |
0.361 |
|
1998 |
Downes GB, Copeland NG, Jenkins NA, Gautam N. Structure and mapping of the G protein gamma3 subunit gene and a divergently transcribed novel gene, gng3lg. Genomics. 53: 220-30. PMID 9790771 DOI: 10.1006/Geno.1998.5508 |
0.746 |
|
1998 |
Gautam N, Downes GB, Yan K, Kisselev O. The G-protein betagamma complex. Cellular Signalling. 10: 447-55. PMID 9754712 DOI: 10.1016/S0898-6568(98)00006-0 |
0.781 |
|
1998 |
Kalyanaraman S, Copeland NG, Gilbert DG, Jenkins NA, Gautam N. Structure and chromosomal localization of mouse G protein subunit gamma 4 gene. Genomics. 49: 147-51. PMID 9570961 DOI: 10.1006/Geno.1998.5223 |
0.548 |
|
1998 |
Kisselev OG, Kao J, Ponder JW, Fann YC, Gautam N, Marshall GR. Light-activated rhodopsin induces structural binding motif in G protein alpha subunit. Proceedings of the National Academy of Sciences of the United States of America. 95: 4270-5. PMID 9539726 DOI: 10.1073/Pnas.95.8.4270 |
0.511 |
|
1998 |
Garcı́a DE, Li B, Garcı́a-Ferreiro RE, Hernández-Ochoa EO, Yan K, Gautam N, Catterall WA, Mackie K, Hille B. G-Protein β-Subunit Specificity in the Fast Membrane-Delimited Inhibition of Ca2+ Channels The Journal of Neuroscience. 18: 9163-9170. DOI: 10.1523/Jneurosci.18-22-09163.1998 |
0.401 |
|
1998 |
Azpiazu I, Gautam N. G protein ysubunit interaction with muscarinic receptors Faseb Journal. 12: A1365. |
0.401 |
|
1997 |
Giambarella U, Yamatsuji T, Okamoto T, Matsui T, Ikezu T, Murayama Y, Levine MA, Katz A, Gautam N, Nishimoto I. G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP. The Embo Journal. 16: 4897-907. PMID 9305632 DOI: 10.1093/Emboj/16.16.4897 |
0.516 |
|
1997 |
Yan K, Gautam N. Structural determinants for interaction with three different effectors on the G protein beta subunit. The Journal of Biological Chemistry. 272: 2056-9. PMID 8999902 DOI: 10.1074/Jbc.272.4.2056 |
0.441 |
|
1996 |
Wang JL, Kalyanaraman S, Vivo MD, Gautam N. Bombesin and thrombin affect discrete pools of intracellular calcium through different G-proteins. The Biochemical Journal. 320: 87-91. PMID 8947471 DOI: 10.1042/Bj3200087 |
0.405 |
|
1996 |
Yan K, Gautam N. A domain on the G protein beta subunit interacts with both adenylyl cyclase 2 and the muscarinic atrial potassium channel. The Journal of Biological Chemistry. 271: 17597-600. PMID 8663592 DOI: 10.1074/Jbc.271.30.17597 |
0.476 |
|
1996 |
Yan K, Kalyanaraman V, Gautam N. Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families. The Journal of Biological Chemistry. 271: 7141-6. PMID 8636150 DOI: 10.1074/Jbc.271.12.7141 |
0.538 |
|
1996 |
Downes G, Kalyanaraman S, Fong H, Gautam N. Gene structure and expression of g protein subunits Faseb Journal. 10: A1099. |
0.754 |
|
1995 |
Kisselev O, Ermolaeva M, Gautam N. Efficient interaction with a receptor requires a specific type of prenyl group on the G protein gamma subunit. The Journal of Biological Chemistry. 270: 25356-8. PMID 7592699 DOI: 10.1074/Jbc.270.43.25356 |
0.571 |
|
1995 |
Kisselev O, Pronin A, Ermolaeva M, Gautam N. Receptor-G protein coupling is established by a potential conformational switch in the beta gamma complex. Proceedings of the National Academy of Sciences of the United States of America. 92: 9102-6. PMID 7568081 DOI: 10.1073/Pnas.92.20.9102 |
0.567 |
|
1995 |
Kalyanaraman S, Kalyanaraman V, Gautam N. A brain-specific G protein gamma subunit. Biochemical and Biophysical Research Communications. 216: 126-32. PMID 7488078 DOI: 10.1006/Bbrc.1995.2600 |
0.492 |
|
1994 |
Kisselev OG, Ermolaeva MV, Gautam N. A farnesylated domain in the G protein gamma subunit is a specific determinant of receptor coupling. The Journal of Biological Chemistry. 269: 21399-402. PMID 8063769 |
0.467 |
|
1994 |
Pronin AN, Gautam N. Characterization of antibodies for various G-protein beta and gamma subunits. Methods in Enzymology. 237: 482-98. PMID 7935022 DOI: 10.1016/S0076-6879(94)37085-0 |
0.527 |
|
1994 |
Gallagher C, Gautam N. Design of oligonucleotide probes for molecular cloning of beta and gamma subunits. Methods in Enzymology. 237: 471-82. PMID 7935021 DOI: 10.1016/S0076-6879(94)37084-2 |
0.492 |
|
1993 |
Pronin AN, Gautam N. Proper processing of a G protein gamma subunit depends on complex formation with a beta subunit. Febs Letters. 328: 89-93. PMID 8344437 DOI: 10.1016/0014-5793(93)80971-V |
0.532 |
|
1993 |
Kisselev O, Gautam N. Specific interaction with rhodopsin is dependent on the gamma subunit type in a G protein. The Journal of Biological Chemistry. 268: 24519-22. PMID 8227005 |
0.53 |
|
1992 |
Pronin AN, Gautam N. Interaction between G-protein beta and gamma subunit types is selective. Proceedings of the National Academy of Sciences of the United States of America. 89: 6220-4. PMID 1631113 DOI: 10.1073/Pnas.89.13.6220 |
0.538 |
|
1991 |
Simon MI, Strathmann MP, Gautam N. Diversity of G proteins in signal transduction. Science (New York, N.Y.). 252: 802-8. PMID 1902986 DOI: 10.1126/Science.1902986 |
0.721 |
|
1991 |
Simonds WF, Butrynski JE, Gautam N, Unson CG, Spiegel AM. G-protein beta gamma dimers. Membrane targeting requires subunit coexpression and intact gamma C-A-A-X domain. The Journal of Biological Chemistry. 266: 5363-6. PMID 1706334 |
0.463 |
|
1990 |
Gautam N, Northup J, Tamir H, Simon MI. G protein diversity is increased by associations with a variety of gamma subunits. Proceedings of the National Academy of Sciences of the United States of America. 87: 7973-7. PMID 2122451 DOI: 10.1073/Pnas.87.20.7973 |
0.723 |
|
1989 |
Gautam N, Baetscher M, Aebersold R, Simon MI. A G protein gamma subunit shares homology with ras proteins. Science (New York, N.Y.). 244: 971-4. PMID 2499046 DOI: 10.1126/Science.2499046 |
0.705 |
|
1988 |
Amatruda TT, Gautam N, Fong HK, Northup JK, Simon MI. The 35- and 36-kDa beta subunits of GTP-binding regulatory proteins are products of separate genes. The Journal of Biological Chemistry. 263: 5008-11. PMID 3128533 |
0.563 |
|
1983 |
Gautam N. Identification of two closely located larval salivary protein genes in Drosophila melanogaster Mgg Molecular & General Genetics. 189: 495-500. DOI: 10.1007/BF00325916 |
0.318 |
|
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