| Year |
Citation |
Score |
| 2024 |
Johnson BP, Mandal PS, Brown SM, Thomas LM, Singh S. Ternary complexes of isopentenyl phosphate kinase from Thermococcus paralvinellae reveal molecular determinants of non-natural substrate specificity. Proteins. PMID 38333996 DOI: 10.1002/prot.26674 |
0.345 |
|
| 2021 |
Johnson BP, Kumar V, Scull EM, Thomas LM, Bourne CR, Singh S. . Acs Chemical Biology. PMID 34905349 DOI: 10.1021/acschembio.1c00655 |
0.351 |
|
| 2020 |
Gardner ED, Dimas DA, Finneran MC, Brown SM, Burgett AW, Singh S. Indole C6 Functionalization of Tryprostatin B Using Prenyltransferase CdpNPT. Catalysts (Basel, Switzerland). 10. PMID 33643664 DOI: 10.3390/catal10111247 |
0.306 |
|
| 2020 |
Scull EM, Bandari C, Johnson BP, Gardner ED, Tonelli M, You J, Cichewicz RH, Singh S. Chemoenzymatic synthesis of daptomycin analogs active against daptomycin-resistant strains. Applied Microbiology and Biotechnology. PMID 32725322 DOI: 10.1007/S00253-020-10790-X |
0.365 |
|
| 2020 |
Johnson BP, Scull EM, Dimas DA, Bavineni T, Bandari C, Batchev AL, Gardner ED, Nimmo SL, Singh S. Acceptor substrate determines donor specificity of an aromatic prenyltransferase: expanding the biocatalytic potential of NphB. Applied Microbiology and Biotechnology. PMID 32189045 DOI: 10.1007/S00253-020-10529-8 |
0.349 |
|
| 2019 |
Bandari C, Scull EM, Bavineni T, Nimmo SL, Gardner ED, Bensen RC, Burgett AW, Singh S. FgaPT2, a biocatalytic tool for alkyl-diversification of indole natural products. Medchemcomm. 10: 1465-1475. PMID 31534661 DOI: 10.1039/C9Md00177H |
0.439 |
|
| 2017 |
Bandari C, Scull EM, Masterson JM, Tran RHQ, Foster SB, Nicholas KM, Singh S. Determination of alkyl-donor promiscuity of tyrosine-O-prenyltransferase SirD from Leptosphaeria maculans. Chembiochem : a European Journal of Chemical Biology. PMID 28960770 DOI: 10.1002/Cbic.201700469 |
0.373 |
|
| 2017 |
Elshahawi SI, Cao H, Shaaban KA, Ponomareva LV, Subramanian T, Farman ML, Spielmann HP, Phillips GN, Thorson JS, Singh S. Structure and specificity of a permissive bacterial C-prenyltransferase. Nature Chemical Biology. PMID 28166207 DOI: 10.1038/Nchembio.2285 |
0.583 |
|
| 2016 |
Huber TD, Wang F, Singh S, Johnson BR, Zhang J, Sunkara M, Van Lanen SG, Morris AJ, Phillips GN, Thorson JS. Functional AdoMet isosteres resistant to classical AdoMet degradation pathways. Acs Chemical Biology. PMID 27351335 DOI: 10.1021/Acschembio.6B00348 |
0.597 |
|
| 2016 |
Cao H, Tan K, Wang F, Bigelow L, Yennamalli RM, Jedrzejczak R, Babnigg G, Bingman CA, Joachimiak A, Kharel MK, Singh S, Thorson JS, Phillips GN. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Structural Dynamics (Melville, N.Y.). 3: 034702. PMID 27191010 DOI: 10.1063/1.4948539 |
0.613 |
|
| 2016 |
Han L, Singh S, Thorson JS, Phillips GN. Loop dynamics of thymidine diphosphate-rhamnose 3'-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis. Structural Dynamics (Melville, N.Y.). 3: 012004. PMID 26958582 DOI: 10.1063/1.4941368 |
0.615 |
|
| 2015 |
Peltier-Pain P, Singh S, Thorson JS. Characterization of early enzymes involved in TDP-aminodideoxypentose biosynthesis en route to indolocarbazole AT2433. Chembiochem : a European Journal of Chemical Biology. PMID 26289554 DOI: 10.1002/Cbic.201500365 |
0.569 |
|
| 2015 |
Singh S, Michalska K, Bigelow L, Endres M, Kharel MK, Babnigg G, Yennamalli RM, Bingman CA, Joachimiak A, Thorson JS, Phillips GN. Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis. The Journal of Biological Chemistry. PMID 26240141 DOI: 10.1074/Jbc.M115.673459 |
0.62 |
|
| 2015 |
Singh S, Kim Y, Wang F, Bigelow L, Endres M, Kharel MK, Babnigg G, Bingman CA, Joachimiak A, Thorson JS, Phillips GN. Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis. Proteins. 83: 1547-54. PMID 26061967 DOI: 10.1002/Prot.24844 |
0.656 |
|
| 2015 |
Wang F, Singh S, Xu W, Helmich KE, Miller MD, Cao H, Bingman CA, Thorson JS, Phillips GN. Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. Acs Chemical Biology. PMID 26023720 DOI: 10.1021/Acschembio.5B00244 |
0.644 |
|
| 2014 |
Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, et al. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. Acs Chemical Biology. 9: 2347-58. PMID 25079510 DOI: 10.1021/Cb500327M |
0.569 |
|
| 2014 |
Chen Z, Zhang J, Singh S, Peltier-Pain P, Thorson JS, Hinds BJ. Functionalized anodic aluminum oxide membrane-electrode system for enzyme immobilization. Acs Nano. 8: 8104-12. PMID 25025628 DOI: 10.1021/Nn502181K |
0.57 |
|
| 2014 |
Singh S, Nandurkar NS, Thorson JS. Characterization of the calicheamicin orsellinate C2-O-methyltransferase CalO6. Chembiochem : a European Journal of Chemical Biology. 15: 1418-21. PMID 24978950 DOI: 10.1002/Cbic.201402119 |
0.601 |
|
| 2014 |
Singh S, Peltier-Pain P, Tonelli M, Thorson JS. A general NMR-based strategy for the in situ characterization of sugar-nucleotide-dependent biosynthetic pathways. Organic Letters. 16: 3220-3. PMID 24911465 DOI: 10.1021/Ol501241A |
0.591 |
|
| 2014 |
Zhang J, Singh S, Hughes RR, Zhou M, Sunkara M, Morris AJ, Thorson JS. A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. Chembiochem : a European Journal of Chemical Biology. 15: 647-52. PMID 24677528 DOI: 10.1002/Cbic.201300779 |
0.566 |
|
| 2014 |
Wang F, Singh S, Zhang J, Huber TD, Helmich KE, Sunkara M, Hurley KA, Goff RD, Bingman CA, Morris AJ, Thorson JS, Phillips GN. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. The Febs Journal. 281: 4224-39. PMID 24649856 DOI: 10.1111/Febs.12784 |
0.641 |
|
| 2014 |
Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angewandte Chemie (International Ed. in English). 53: 3965-9. PMID 24616228 DOI: 10.1002/Anie.201308272 |
0.607 |
|
| 2014 |
Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2. The Journal of Antibiotics. 67: 223-30. PMID 24252813 DOI: 10.1038/Ja.2013.113 |
0.556 |
|
| 2014 |
Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6. Natural Product Research. 28: 337-9. PMID 24237421 DOI: 10.1080/14786419.2013.855932 |
0.59 |
|
| 2014 |
Chen Z, Zhang J, Singh S, Peltier-Pain P, Thorson JS, Hinds BJ. Functionalized anodic aluminum oxide membrane-electrode system for enzyme immobilization Acs Nano. 8: 8104-8112. DOI: 10.1021/nn502181k |
0.46 |
|
| 2013 |
Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN, Thorson JS. Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. Acs Chemical Biology. 8: 1632-9. PMID 23662776 DOI: 10.1021/Cb400068K |
0.633 |
|
| 2013 |
Gantt RW, Peltier-Pain P, Singh S, Zhou M, Thorson JS. Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 7648-53. PMID 23610417 DOI: 10.1073/Pnas.1220220110 |
0.557 |
|
| 2013 |
Wang F, Zhou M, Singh S, Yennamalli RM, Bingman CA, Thorson JS, Phillips GN. Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins. 81: 1277-82. PMID 23526584 DOI: 10.1002/Prot.24289 |
0.615 |
|
| 2012 |
Singh S, Phillips GN, Thorson JS. The structural biology of enzymes involved in natural product glycosylation. Natural Product Reports. 29: 1201-37. PMID 22688446 DOI: 10.1039/C2Np20039B |
0.624 |
|
| 2011 |
Chang A, Singh S, Helmich KE, Goff RD, Bingman CA, Thorson JS, Phillips GN. Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proceedings of the National Academy of Sciences of the United States of America. 108: 17649-54. PMID 21987796 DOI: 10.1073/Pnas.1108484108 |
0.641 |
|
| 2011 |
Chang A, Singh S, Phillips GN, Thorson JS. Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation. Current Opinion in Biotechnology. 22: 800-8. PMID 21592771 DOI: 10.1016/J.Copbio.2011.04.013 |
0.558 |
|
| 2011 |
Singh S, Chang A, Goff RD, Bingman CA, Grüschow S, Sherman DH, Phillips GN, Thorson JS. Structural characterization of the mitomycin 7-O-methyltransferase. Proteins. 79: 2181-8. PMID 21538548 DOI: 10.1002/Prot.23040 |
0.641 |
|
| 2011 |
Goff RD, Singh S, Thorson JS. Glycosyloxyamine neoglycosylation: a model study using calicheamicin. Chemmedchem. 6: 774-6. PMID 21520418 DOI: 10.1002/Cmdc.201100028 |
0.589 |
|
| 2011 |
Chang A, Singh S, Bingman CA, Thorson JS, Phillips GN. Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway. Acta Crystallographica. Section D, Biological Crystallography. 67: 197-203. PMID 21358050 DOI: 10.1107/S090744491100360X |
0.641 |
|
| 2009 |
McCoy JG, Johnson HD, Singh S, Bingman CA, Lei IK, Thorson JS, Phillips GN. Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway. Proteins. 74: 50-60. PMID 18561189 DOI: 10.1002/Prot.22131 |
0.629 |
|
| 2009 |
Sahu SC, Singh S, Tonelli M, Markley JL. Solution structure of At3g03773.1 protein from Arabidopsis thaliana Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kmw/Pdb |
0.323 |
|
| 2008 |
Zhang C, Bitto E, Goff RD, Singh S, Bingman CA, Griffith BR, Albermann C, Phillips GN, Thorson JS. Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chemistry & Biology. 15: 842-53. PMID 18721755 DOI: 10.1016/J.Chembiol.2008.06.011 |
0.625 |
|
| 2008 |
Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN, Thorson JS. Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. The Journal of Biological Chemistry. 283: 22628-36. PMID 18502766 DOI: 10.1074/Jbc.M800503200 |
0.616 |
|
| 2008 |
Bitto E, Huang Y, Bingman CA, Singh S, Thorson JS, Phillips GN. The structure of flavin-dependent tryptophan 7-halogenase RebH. Proteins. 70: 289-93. PMID 17876823 DOI: 10.1002/Prot.21627 |
0.601 |
|
| 2006 |
Singh S, Hager MH, Zhang C, Griffith BR, Lee MS, Hallenga K, Markley JL, Thorson JS. Structural insight into the self-sacrifice mechanism of enediyne resistance. Acs Chemical Biology. 1: 451-60. PMID 17168523 DOI: 10.1021/Cb6002898 |
0.576 |
|
| 2006 |
Tyler RC, Bitto E, Berndsen CE, Bingman CA, Singh S, Lee MS, Wesenberg GE, Denu JM, Phillips GN, Markley JL. Structure of Arabidopsis thaliana At1g77540 protein, a minimal acetyltransferase from the COG2388 family. Biochemistry. 45: 14325-36. PMID 17128971 DOI: 10.1021/Bi0612059 |
0.4 |
|
| 2005 |
Singh S, Cornilescu CC, Tyler RC, Cornilescu G, Tonelli M, Lee MS, Markley JL. Solution structure of a late embryogenesis abundant protein (LEA14) from Arabidopsis thaliana, a cellular stress-related protein. Protein Science : a Publication of the Protein Society. 14: 2601-9. PMID 16155204 DOI: 10.1110/Ps.051579205 |
0.323 |
|
| 2005 |
Singh S, Tonelli M, Tyler RC, Bahrami A, Lee MS, Markley JL. Three-dimensional structure of the AAH26994.1 protein from Mus musculus, a putative eukaryotic Urm1. Protein Science : a Publication of the Protein Society. 14: 2095-102. PMID 16046629 DOI: 10.1110/Ps.051577605 |
0.391 |
|
| 2005 |
Tyler RC, Aceti DJ, Bingman CA, Cornilescu CC, Fox BG, Frederick RO, Jeon WB, Lee MS, Newman CS, Peterson FC, Phillips GN, Shahan MN, Singh S, Song J, Sreenath HK, et al. Comparison of cell-based and cell-free protocols for producing target proteins from the Arabidopsis thaliana genome for structural studies. Proteins. 59: 633-43. PMID 15789406 DOI: 10.1002/Prot.20436 |
0.352 |
|
| 2005 |
Tyler RC, Sreenath HK, Singh S, Aceti DJ, Bingman CA, Markley JL, Fox BG. Auto-induction medium for the production of [U-15N]- and [U-13C, U-15N]-labeled proteins for NMR screening and structure determination. Protein Expression and Purification. 40: 268-78. PMID 15766868 DOI: 10.1016/J.Pep.2004.12.024 |
0.322 |
|
| 2004 |
Singh S, Tyler RC, Lee MS, Markley JL. Solution structure of AT3g03773 from Arabidopsis Thaliana Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb1Xo9/Pdb |
0.315 |
|
| 2004 |
Singh S, Cornilescu CC, Tyler RC, Cornilescu G, Tonelli M, Lee MS, Markley JL. Solution structure of AT1g01470 from Arabidopsis Thaliana Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb1Xo8/Pdb |
0.315 |
|
| 2004 |
Singh S, Tonelli M, Tyler RC, Bahrami A, Lee MS, Markley JL. Solution Structure of Ubiquitin like protein from Mus musculus Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb1Xo3/Pdb |
0.327 |
|
| 2004 |
Cornilescu C, Cornilescu G, Singh S, Lee M, Tyler E, Shahan M, Vinarov D, Markley J. Solution structure of At5g66040, a putative protein from Arabidopsis Thaliana Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr6240 |
0.327 |
|
| 2002 |
Singh S, Folkers GE, Bonvin AM, Boelens R, Wechselberger R, Niztayev A, Kaptein R. Solution structure and DNA-binding properties of the C-terminal domain of UvrC from E.coli. The Embo Journal. 21: 6257-66. PMID 12426397 DOI: 10.1093/Emboj/Cdf627 |
0.341 |
|
| 1997 |
Singh S, Patel PK, Hosur RV. Structural polymorphism and dynamism in the DNA segment GATCTTCCCCCCGGAA: NMR investigations of hairpin, dumbbell, nicked duplex, parallel strands, and i-motif. Biochemistry. 36: 13214-13222. PMID 9341210 DOI: 10.1021/Bi970819Y |
0.376 |
|
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