Robert L. Martuza - Publications

Massachusetts General Hospital, Boston, MA 

214 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nigim F, Kiyokawa J, Gurtner A, Kawamura Y, Hua L, Kasper EM, Brastianos PK, Cahill DP, Rabkin SD, Martuza RL, Carbonell WS, Wakimoto H. A Monoclonal Antibody Against β1 Integrin Inhibits Proliferation and Increases Survival in an Orthotopic Model of High-Grade Meningioma. Targeted Oncology. PMID 31301014 DOI: 10.1007/s11523-019-00654-4  0.6
2019 Ning JF, Stanciu M, Humphrey MR, Gorham J, Wakimoto H, Nishihara R, Lees J, Zou L, Martuza RL, Wakimoto H, Rabkin SD. Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma. Nature Communications. 10: 2910. PMID 31266951 DOI: 10.1038/s41467-019-10993-5  0.6
2019 Wang L, Ning J, Wakimoto H, Wu S, Wu CL, Humphrey MR, Rabkin SD, Martuza RL. Oncolytic Herpes Simplex Virus and PI3K Inhibitor BKM120 Synergize to Promote Killing of Prostate Cancer Stem-like Cells. Molecular Therapy Oncolytics. 13: 58-66. PMID 31016228 DOI: 10.1016/j.omto.2019.03.008  0.6
2019 Tanaka S, Luk S, Kiyokawa J, Onozato ML, Iafrate AJ, Shah K, Martuza RL, Rabkin SD, Batchelor TT, Cahill DP, Chi AS, Wakimoto H. Genetically distinct glioma stem-like cell xenografts established from paired glioblastoma samples harvested before and after molecularly targeted therapy. Scientific Reports. 9: 139. PMID 30644426 DOI: 10.1038/s41598-018-37437-2  0.6
2018 Saha D, Martuza RL, Rabkin SD. Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma. Immunotherapy. 10: 779-786. PMID 30008259 DOI: 10.2217/imt-2018-0009  0.6
2018 Peters C, Paget M, Tshilenge KT, Saha D, Antoszczyk S, Baars A, Frost T, Martuza RL, Wakimoto H, Rabkin SD. RESTRICTION OF γ34.5-DELETED ONCOLYTIC HERPES SIMPLEX VIRUS REPLICATION IN GLIOBLASTOMA STEM-LIKE CELLS. Journal of Virology. PMID 29793956 DOI: 10.1128/JVI.00246-18  0.6
2018 Saha D, Wakimoto H, Peters CW, Antoszczyk SJ, Rabkin SD, Martuza RL. Combinatorial effects of VEGFR kinase inhibitor axitinib and oncolytic virotherapy in mouse and human glioblastoma stem-like cell models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29599413 DOI: 10.1158/1078-0432.CCR-17-1717  0.6
2017 Saha D, Martuza RL, Rabkin SD. Curing glioblastoma: oncolytic HSV-IL12 and checkpoint blockade. Oncoscience. 4: 67-69. PMID 28966936 DOI: 10.18632/oncoscience.359  0.6
2017 Saha D, Martuza RL, Rabkin SD. Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade. Cancer Cell. 32: 253-267.e5. PMID 28810147 DOI: 10.1016/j.ccell.2017.07.006  0.6
2017 Esaki S, Nigim F, Moon E, Luk S, Kiyokawa J, Curry W, Cahill DP, Chi AS, Iafrate AJ, Martuza RL, Rabkin SD, Wakimoto H. Blockade of transforming growth factor-β signaling enhances oncolytic herpes simplex virus efficacy in patient-derived recurrent glioblastoma models. International Journal of Cancer. PMID 28801914 DOI: 10.1002/ijc.30929  0.6
2017 Ning J, Wakimoto H, Peters C, Martuza RL, Rabkin SD. Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma. Journal of the National Cancer Institute. 109: 1-13. PMID 28376211 DOI: 10.1093/jnci/djw229  0.6
2016 Esaki S, Rabkin SD, Martuza RL, Wakimoto H. Transient fasting enhances replication of oncolytic herpes simplex virus in glioblastoma. American Journal of Cancer Research. 6: 300-11. PMID 27186404  0.6
2016 Nigim F, Esaki SI, Hood M, Lelic N, James MF, Ramesh V, Stemmer-Rachamimov A, Cahill DP, Brastianos PK, Rabkin SD, Martuza RL, Wakimoto H. A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus. Neuro-Oncology. PMID 26951380 DOI: 10.1093/neuonc/now031  0.6
2015 Hwang WL, Marciscano AE, Niemierko A, Kim DW, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Loeffler JS, Oh KS, Shih HA, Larvie M. Imaging and extent of surgical resection predict risk of meningioma recurrence better than WHO histopathological grade. Neuro-Oncology. PMID 26597949 DOI: 10.1093/neuonc/nov285  0.6
2015 Nigim F, Cavanaugh J, Patel AP, Curry WT, Esaki S, Kasper EM, Chi AS, Louis DN, Martuza RL, Rabkin SD, Wakimoto H. Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment. Journal of Neuropathology and Experimental Neurology. 74: 710-22. PMID 26083570 DOI: 10.1097/NEN.0000000000000210  0.6
2015 Lu L, Saha D, Martuza RL, Rabkin SD, Wakimoto H. Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma. Journal of Neuro-Oncology. 121: 91-100. PMID 25213669 DOI: 10.1007/s11060-014-1612-1  0.6
2014 Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science (New York, N.Y.). 344: 1396-401. PMID 24925914 DOI: 10.1126/science.1254257  0.6
2014 Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell. 157: 580-94. PMID 24726434 DOI: 10.1016/j.cell.2014.02.030  0.6
2014 Antoszczyk S, Spyra M, Mautner VF, Kurtz A, Stemmer-Rachamimov AO, Martuza RL, Rabkin SD. Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus. Neuro-Oncology. 16: 1057-66. PMID 24470552 DOI: 10.1093/neuonc/not317  0.6
2014 Sheth SA, Tirino JL, Martuza RL. Vestibular schwannoma: suboccipital approach. Neurosurgical Focus. 36: 1. PMID 24380512 DOI: 10.3171/2014.V1.FOCUS13318  0.6
2013 Cheema TA, Wakimoto H, Fecci PE, Ning J, Kuroda T, Jeyaretna DS, Martuza RL, Rabkin SD. Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model. Proceedings of the National Academy of Sciences of the United States of America. 110: 12006-11. PMID 23754388 DOI: 10.1073/pnas.1307935110  0.6
2013 Zhang W, Fulci G, Wakimoto H, Cheema TA, Buhrman JS, Jeyaretna DS, Stemmer Rachamimov AO, Rabkin SD, Martuza RL. Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models. Neoplasia (New York, N.Y.). 15: 591-9. PMID 23730207 DOI: 10.1593/neo.13158  0.6
2013 Rheinbay E, Suvà ML, Gillespie SM, Wakimoto H, Patel AP, Shahid M, Oksuz O, Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S, Chi AS, Bernstein BE. An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma. Cell Reports. 3: 1567-79. PMID 23707066 DOI: 10.1016/j.celrep.2013.04.021  0.6
2013 Las Heras F, Martuza R, Caruso P, Rincon S, Stemmer-Rachamimov A. 24-Year-old woman with an internal auditory canal mass Brain Pathology. 23: 361-362. PMID 23587143 DOI: 10.1111/bpa.12055  0.6
2013 Passer BJ, Cheema T, Wu S, Wu CL, Rabkin SD, Martuza RL. Combination of vinblastine and oncolytic herpes simplex virus vector expressing IL-12 therapy increases antitumor and antiangiogenic effects in prostate cancer models. Cancer Gene Therapy. 20: 17-24. PMID 23138870 DOI: 10.1038/cgt.2012.75  0.6
2013 Tamura K, Wakimoto H, Agarwal AS, Rabkin SD, Bhere D, Martuza RL, Kuroda T, Kasmieh R, Shah K. Multimechanistic tumor targeted oncolytic virus overcomes resistance in brain tumors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 68-77. PMID 22929661 DOI: 10.1038/mt.2012.175  0.6
2012 Sgubin D, Wakimoto H, Kanai R, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus counteracts the hypoxia-induced modulation of glioblastoma stem-like cells. Stem Cells Translational Medicine. 1: 322-32. PMID 23197811 DOI: 10.5966/sctm.2011-0035  0.6
2012 Ginat DT, Martuza RL. Postoperative imaging of vestibular schwannomas. Neurosurgical Focus. 33: E18. PMID 22937852 DOI: 10.3171/2012.6.FOCUS12150  0.6
2012 Barnard Z, Wakimoto H, Zaupa C, Patel AP, Klehm J, Martuza RL, Rabkin SD, Curry WT. Expression of FMS-like tyrosine kinase 3 ligand by oncolytic herpes simplex virus type I prolongs survival in mice bearing established syngeneic intracranial malignant glioma. Neurosurgery. 71: 741-8; discussion 74. PMID 22653387 DOI: 10.1227/NEU.0b013e318260fd73  0.6
2012 Kanai R, Zaupa C, Sgubin D, Antoszczyk SJ, Martuza RL, Wakimoto H, Rabkin SD. Effect of γ34.5 deletions on oncolytic herpes simplex virus activity in brain tumors. Journal of Virology. 86: 4420-31. PMID 22345479 DOI: 10.1128/JVI.00017-12  0.6
2012 Kanai R, Rabkin SD, Yip S, Sgubin D, Zaupa CM, Hirose Y, Louis DN, Wakimoto H, Martuza RL. Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. Journal of the National Cancer Institute. 104: 42-55. PMID 22173583 DOI: 10.1093/jnci/djr509  0.6
2012 Wakimoto H, Mohapatra G, Kanai R, Curry WT, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. Neuro-Oncology. 14: 132-44. PMID 22067563 DOI: 10.1093/neuonc/nor195  0.6
2012 Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 37-45. PMID 21915104 DOI: 10.1038/mt.2011.187  0.6
2012 Martuza RL. Suboccipital Retrosigmoid Surgical Approach for Vestibular Schwannoma (Acoustic Neuroma) Schmidek and Sweet Operative Neurosurgical Techniques: Indications, Methods, and Results: Sixth Edition. 1: 546-554. DOI: 10.1016/B978-1-4160-6839-6.10045-0  0.6
2011 Cheema TA, Kanai R, Kim GW, Wakimoto H, Passer B, Rabkin SD, Martuza RL. Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7383-93. PMID 21976549 DOI: 10.1158/1078-0432.CCR-11-1762  0.6
2011 Kleijn A, Chen JW, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G. Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4484-93. PMID 21558403 DOI: 10.1158/1078-0432.CCR-11-0575  0.6
2011 Kanai R, Wakimoto H, Martuza RL, Rabkin SD. A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3686-96. PMID 21505062 DOI: 10.1158/1078-0432.CCR-10-3142  0.6
2011 Elstner A, Stockhammer F, Nguyen-Dobinsky TN, Nguyen QL, Pilgermann I, Gill A, Guhr A, Zhang T, von Eckardstein K, Picht T, Veelken J, Martuza RL, von Deimling A, Kurtz A. Identification of diagnostic serum protein profiles of glioblastoma patients. Journal of Neuro-Oncology. 102: 71-80. PMID 20617365 DOI: 10.1007/s11060-010-0284-8  0.6
2010 Passer BJ, Cheema T, Zhou B, Wakimoto H, Zaupa C, Razmjoo M, Sarte J, Wu S, Wu CL, Noah JW, Li Q, Buolamwini JK, Yen Y, Rabkin SD, Martuza RL. Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication. Cancer Research. 70: 3890-5. PMID 20424118 DOI: 10.1158/0008-5472.CAN-10-0155  0.6
2010 Castelo-Branco P, Passer BJ, Buhrman JS, Antoszczyk S, Marinelli M, Zaupa C, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus armed with xenogeneic homologue of prostatic acid phosphatase enhances antitumor efficacy in prostate cancer. Gene Therapy. 17: 805-10. PMID 20220784 DOI: 10.1038/gt.2010.20  0.6
2009 Passer BJ, Wu CL, Wu S, Rabkin SD, Martuza RL. Analysis of genetically engineered oncolytic herpes simplex viruses in human prostate cancer organotypic cultures. Gene Therapy. 16: 1477-82. PMID 19693098 DOI: 10.1038/gt.2009.94  0.6
2009 Stankovic KM, Mrugala MM, Martuza RL, Silver M, Betensky RA, Nadol JB, Stemmer-Rachamimov AO. Genetic determinants of hearing loss associated with vestibular schwannomas. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 30: 661-7. PMID 19546833 DOI: 10.1097/MAO.0b013e3181a66ece  0.6
2009 Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Research. 69: 3472-81. PMID 19351838 DOI: 10.1158/0008-5472.CAN-08-3886  0.6
2009 Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 4822-7. PMID 19264968 DOI: 10.1073/pnas.0806647106  0.6
2009 Passer BJ, Castelo-Branco P, Buhrman JS, Varghese S, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus vectors and taxanes synergize to promote killing of prostate cancer cells. Cancer Gene Therapy. 16: 551-60. PMID 19197321 DOI: 10.1038/cgt.2009.10  0.6
2009 Aghi MK, Carter BS, Cosgrove GR, Ojemann RG, Amin-Hanjani S, Martuza RL, Curry WT, Barker FG. Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation. Neurosurgery. 64: 56-60; discussion 60. PMID 19145156 DOI: 10.1227/01.NEU.0000330399.55586.63  0.6
2009 Aghi MK, Liu TC, Rabkin S, Martuza RL. Hypoxia enhances the replication of oncolytic herpes simplex virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 51-6. PMID 18957963 DOI: 10.1038/mt.2008.232  0.6
2008 Farrell CJ, Zaupa C, Barnard Z, Maley J, Martuza RL, Rabkin SD, Curry WT. Combination immunotherapy for tumors via sequential intratumoral injections of oncolytic herpes simplex virus 1 and immature dendritic cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7711-6. PMID 19047097 DOI: 10.1158/1078-0432.CCR-08-1364  0.6
2008 Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A. Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes. The American Journal of Pathology. 173: 1861-72. PMID 18988803 DOI: 10.2353/ajpath.2008.080376  0.6
2008 Liu TC, Castelo-Branco P, Rabkin SD, Martuza RL. Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1041-7. PMID 18388912 DOI: 10.1038/mt.2008.58  0.6
2008 Sher DJ, Henson JW, Avutu B, Hochberg FH, Batchelor TT, Martuza RL, Barker FG, Loeffler JS, Chakravarti A. The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma. Journal of Neuro-Oncology. 88: 43-50. PMID 18231723 DOI: 10.1007/s11060-008-9530-8  0.6
2008 Curry WT, Martuza RL. Viral oncolysis of glioblastoma Neurotropic Viral Infections. 407-424. DOI: 10.1017/CBO9780511541728.027  0.6
2007 Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Stemmer-Rachamimov AO, Rachamimov AS, ... ... Martuza RL, et al. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Research. 67: 9398-406. PMID 17909049 DOI: 10.1158/0008-5472.CAN-07-1063  0.6
2007 Varghese S, Rabkin SD, Nielsen GP, MacGarvey U, Liu R, Martuza RL. Systemic therapy of spontaneous prostate cancer in transgenic mice with oncolytic herpes simplex viruses. Cancer Research. 67: 9371-9. PMID 17909046 DOI: 10.1158/0008-5472.CAN-07-0674  0.6
2007 Liu TC, Wakimoto H, Martuza RL, Rabkin SD. Herpes simplex virus Us3(-) mutant as oncolytic strategy and synergizes with phosphatidylinositol 3-kinase-Akt targeting molecular therapeutics. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5897-902. PMID 17908985 DOI: 10.1158/1078-0432.CCR-07-1013  0.6
2007 Jeyaretna DS, Rabkin SD, Martuza RL. Oncolytic herpes simplex virus therapy for peripheral nerve tumors. Neurosurgical Focus. 22: E4. PMID 17613221  0.6
2007 Prabhakar S, Messerli SM, Stemmer-Rachamimov AO, Liu TC, Rabkin S, Martuza R, Breakefield XO. Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta. Cancer Gene Therapy. 14: 460-7. PMID 17304235 DOI: 10.1038/sj.cgt.7701037  0.6
2007 Aghi M, Rabkin SD, Martuza RL. Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide. Cancer Research. 67: 440-4. PMID 17234749 DOI: 10.1158/0008-5472.CAN-06-3145  0.6
2007 Martuza RL. Single nucleotide polymorphism 309 affects murin-double-minute 2 protein expression but not glioma tumorigenesis: Commentary Neurologia Medico-Chirurgica. 47: 209.  0.6
2006 Aghi M, Rabkin S, Martuza RL. Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair. Clinical Neurosurgery. 53: 65-76. PMID 17380741  0.6
2006 Liu TC, Zhang T, Fukuhara H, Kuroda T, Todo T, Canron X, Bikfalvi A, Martuza RL, Kurtz A, Rabkin SD. Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6791-9. PMID 17121900 DOI: 10.1158/1078-0432.CCR-06-0263  0.6
2006 Kuroda T, Rabkin SD, Martuza RL. Effective treatment of tumors with strong beta-catenin/T-cell factor activity by transcriptionally targeted oncolytic herpes simplex virus vector. Cancer Research. 66: 10127-35. PMID 17047077 DOI: 10.1158/0008-5472.CAN-06-2744  0.6
2006 Liu TC, Zhang T, Fukuhara H, Kuroda T, Todo T, Martuza RL, Rabkin SD, Kurtz A. Oncolytic HSV armed with platelet factor 4, an antiangiogenic agent, shows enhanced efficacy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 789-97. PMID 17045531 DOI: 10.1016/j.ymthe.2006.07.011  0.6
2006 Martuza RL. Vestibular schwannoma. Journal of Neurosurgery. 105: 526; discussion 526. PMID 17044552 DOI: 10.3171/jns.2006.105.4.526  0.6
2006 Kuroda T, Martuza RL, Todo T, Rabkin SD. Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases. Bmc Biotechnology. 6: 40. PMID 16995942 DOI: 10.1186/1472-6750-6-40  0.6
2006 Varghese S, Rabkin SD, Nielsen PG, Wang W, Martuza RL. Systemic oncolytic herpes virus therapy of poorly immunogenic prostate cancer metastatic to lung. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 2919-27. PMID 16675589 DOI: 10.1158/1078-0432.CCR-05-1187  0.6
2006 Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Human Gene Therapy. 17: 20-30. PMID 16409122 DOI: 10.1089/hum.2006.17.20  0.6
2006 Aghi M, Rabkin S, Martuza RL. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication. Journal of the National Cancer Institute. 98: 38-50. PMID 16391370 DOI: 10.1093/jnci/djj003  0.6
2006 Varghese S, Rabkin SD, Liu R, Nielsen PG, Ipe T, Martuza RL. Enhanced therapeutic efficacy of IL-12, but not GM-CSF, expressing oncolytic herpes simplex virus for transgenic mouse derived prostate cancers. Cancer Gene Therapy. 13: 253-65. PMID 16179929 DOI: 10.1038/sj.cgt.7700900  0.6
2005 Fukuhara H, Ino Y, Kuroda T, Martuza RL, Todo T. Triple gene-deleted oncolytic herpes simplex virus vector double-armed with interleukin 18 and soluble B7-1 constructed by bacterial artificial chromosome-mediated system. Cancer Research. 65: 10663-8. PMID 16322208 DOI: 10.1158/0008-5472.CAN-05-2534  0.6
2005 Aghi M, Martuza RL. Oncolytic viral therapies - the clinical experience. Oncogene. 24: 7802-16. PMID 16299539 DOI: 10.1038/sj.onc.1209037  0.6
2005 Fukuhara H, Martuza RL, Rabkin SD, Ito Y, Todo T. Oncolytic herpes simplex virus vector g47delta in combination with androgen ablation for the treatment of human prostate adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7886-90. PMID 16278413 DOI: 10.1158/1078-0432.CCR-05-1090  0.6
2005 Chan AW, Black P, Ojemann RG, Barker FG, Kooy HM, Lopes VV, McKenna MJ, Shrieve DC, Martuza RL, Loeffler JS. Stereotactic radiotherapy for vestibular schwannomas: favorable outcome with minimal toxicity. Neurosurgery. 57: 60-70; discussion 60. PMID 15987541 DOI: 10.1227/01.NEU.0000163091.12239.BB  0.6
2005 Mashour GA, Walker EE, Martuza RL. Psychosurgery: past, present, and future. Brain Research. Brain Research Reviews. 48: 409-19. PMID 15914249 DOI: 10.1016/j.brainresrev.2004.09.002  0.6
2005 Mashour GA, Drissel SN, Frahm S, Farassati F, Martuza RL, Mautner VF, Kindler-Röhrborn A, Kurtz A. Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids. Oncogene. 24: 2367-74. PMID 15735744 DOI: 10.1038/sj.onc.1208425  0.6
2005 Doolittle ND, Abrey LE, Bleyer WA, Brem S, Davis TP, Dore-Duffy P, Drewes LR, Hall WA, Hoffman JM, Korfel A, Martuza R, Muldoon LL, Peereboom D, Peterson DR, Rabkin SD, et al. New frontiers in translational research in neuro-oncology and the blood-brain barrier: report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 421-8. PMID 15701824  0.6
2005 Liu R, Martuza RL, Rabkin SD. Intracarotid delivery of oncolytic HSV vector G47Delta to metastatic breast cancer in the brain. Gene Therapy. 12: 647-54. PMID 15647762 DOI: 10.1038/  0.6
2004 Mashour GA, Driever PH, Hartmann M, Drissel SN, Zhang T, Scharf B, Felderhoff-Müser U, Sakuma S, Friedrich RE, Martuza RL, Mautner VF, Kurtz A. Circulating growth factor levels are associated with tumorigenesis in neurofibromatosis type 1. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 5677-83. PMID 15355893 DOI: 10.1158/1078-0432.CCR-03-0769  0.6
2004 Kurtz A, Lueth M, Kluwe L, Zhang T, Foster R, Mautner VF, Hartmann M, Tan DJ, Martuza RL, Friedrich RE, Driever PH, Wong LJ. Somatic mitochondrial DNA mutations in neurofibromatosis type 1-associated tumors. Molecular Cancer Research : McR. 2: 433-41. PMID 15328370  0.6
2003 Weber DC, Chan AW, Bussiere MR, Harsh GR, Ancukiewicz M, Barker FG, Thornton AT, Martuza RL, Nadol JB, Chapman PH, Loeffler JS. Proton beam radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicity. Neurosurgery. 53: 577-86; discussion 5. PMID 12943574  0.6
2003 Nikolic B, Feigenbaum F, Abbara S, Martuza RL, Schellinger D. CT changes of an intracranial granulocytic sarcoma on short-term follow-up. Ajr. American Journal of Roentgenology. 180: 78-80. PMID 12490481 DOI: 10.2214/ajr.180.1.1800078  0.6
2002 Kurtz A, Martuza RL. Antiangiogenesis in neurofibromatosis 1. Journal of Child Neurology. 17: 578-84; discussion 6. PMID 12403556  0.6
2001 Jorgensen TJ, Katz S, Wittmack EK, Varghese S, Todo T, Rabkin SD, Martuza RL. Ionizing radiation does not alter the antitumor activity of herpes simplex virus vector G207 in subcutaneous tumor models of human and murine prostate cancer. Neoplasia (New York, N.Y.). 3: 451-6. PMID 11687957 DOI: 10.1038/sj.neo.7900193  0.6
2001 Kirn D, Martuza RL, Zwiebel J. Replication-selective virotherapy for cancer: Biological principles, risk management and future directions. Nature Medicine. 7: 781-7. PMID 11433341 DOI: 10.1038/89901  0.6
2001 Varghese S, Newsome JT, Rabkin SD, McGeagh K, Mahoney D, Nielsen P, Todo T, Martuza RL. Preclinical safety evaluation of G207, a replication-competent herpes simplex virus type 1, inoculated intraprostatically in mice and nonhuman primates. Human Gene Therapy. 12: 999-1010. PMID 11387063 DOI: 10.1089/104303401750195944  0.6
2001 Todo T, Martuza RL, Rabkin SD, Johnson PA. Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proceedings of the National Academy of Sciences of the United States of America. 98: 6396-401. PMID 11353831 DOI: 10.1073/pnas.101136398  0.6
2001 Toda M, Martuza RL, Rabkin SD. Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine. Gene Therapy. 8: 332-9. PMID 11313808 DOI: 10.1038/  0.6
2001 Mashour GA, Moulding HD, Chahlavi A, Khan GA, Rabkin SD, Martuza RL, Driever PH, Kurtz A, Chalavi A. Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model. Experimental Neurology. 169: 64-71. PMID 11312559 DOI: 10.1006/exnr.2001.7641  0.6
2001 Wu A, Mazumder A, Martuza RL, Liu X, Thein M, Meehan KR, Rabkin SD. Biological purging of breast cancer cells using an attenuated replication-competent herpes simplex virus in human hematopoietic stem cell transplantation. Cancer Research. 61: 3009-15. PMID 11306480  0.6
2001 Mashour GA, Ratner N, Khan GA, Wang HL, Martuza RL, Kurtz A. The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells. Oncogene. 20: 97-105. PMID 11244508 DOI: 10.1038/sj.onc.1204026  0.6
2001 Todo T, Martuza RL, Dallman MJ, Rabkin SD. In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity. Cancer Research. 61: 153-61. PMID 11196154  0.6
2001 Barker FG, McKenna M, Poe D, Nadol J, Martuza R, Ojemann R. Acoustic neuromas in the pediatric population: sporadic and nf2 populations Skull Base. 11: 3.  0.6
2000 Todo T, Feigenbaum F, Rabkin SD, Lakeman F, Newsome JT, Johnson PA, Mitchell E, Belliveau D, Ostrove JM, Martuza RL. Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 588-95. PMID 11124059 DOI: 10.1006/mthe.2000.0200  0.6
2000 Toda M, Martuza RL, Rabkin SD. Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 324-9. PMID 11020347 DOI: 10.1006/mthe.2000.0130  0.6
2000 Lim DJ, Rubenstein AE, Evans DG, Jacks T, Seizinger BG, Baser ME, Beebe D, Brackmann DE, Chiocca EA, Fehon RG, Giovannini M, Glazer R, Gusella JF, Gutmann DH, Korf B, ... ... Martuza R, et al. Advances in neurofibromatosis 2 (NF2): a workshop report. Journal of Neurogenetics. 14: 63-106. PMID 10992163  0.6
2000 Moulding HD, Martuza RL, Rabkin SD. Clinical mutations in the L1 neural cell adhesion molecule affect cell-surface expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5696-702. PMID 10908608  0.6
2000 Sandhu FA, Martuza RL. Craniofacial hemangiopericytoma associated with oncogenic osteomalacia: case report. Journal of Neuro-Oncology. 46: 241-7. PMID 10902855 DOI: 10.1023/A:1006352106762  0.6
2000 Todo T, Rabkin SD, Martuza RL. Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors. Cancer Gene Therapy. 7: 939-46. PMID 10880026 DOI: 10.1038/sj.cgt.7700182  0.6
2000 Markert JM, Medlock MD, Rabkin SD, Gillespie GY, Todo T, Hunter WD, Palmer CA, Feigenbaum F, Tornatore C, Tufaro F, Martuza RL. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Therapy. 7: 867-74. PMID 10845725 DOI: 10.1038/  0.6
2000 Sandhu FA, Schellinger D, Martuza RL. A vascular sarcoid mass mimicking a convexity meningioma. Neuroradiology. 42: 195-8. PMID 10772141  0.6
2000 Martuza RL. Conditionally replicating herpes vectors for cancer therapy. The Journal of Clinical Investigation. 105: 841-6. PMID 10749560 DOI: 10.1172/JCI9744  0.6
2000 Sundaresan P, Hunter WD, Martuza RL, Rabkin SD. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice. Journal of Virology. 74: 3832-41. PMID 10729157 DOI: 10.1128/JVI.74.8.3832-3841.2000  0.6
1999 Chahlavi A, Todo T, Martuza RL, Rabkin SD. Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma. Neoplasia (New York, N.Y.). 1: 162-9. PMID 10933051  0.6
1999 Mashour GA, Martuza RL, Kurtz A. Induction of melanogenic abnormalities in NF1+/- mutant mice by DMBA. The Journal of Investigative Dermatology. 113: 1133-4. PMID 10594763 DOI: 10.1046/j.1523-1747.1999.00813.x  0.6
1999 Todo T, Rabkin SD, Chahlavi A, Martuza RL. Corticosteroid administration does not affect viral oncolytic activity, but inhibits antitumor immunity in replication-competent herpes simplex virus tumor therapy. Human Gene Therapy. 10: 2869-78. PMID 10584932 DOI: 10.1089/10430349950016591  0.6
1999 Todo T, Rabkin SD, Sundaresan P, Wu A, Meehan KR, Herscowitz HB, Martuza RL. Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Human Gene Therapy. 10: 2741-55. PMID 10584921 DOI: 10.1089/10430349950016483  0.6
1999 Chahlavi A, Rabkin SD, Todo T, Sundaresan P, Martuza RL. Effect of prior exposure to herpes simplex virus 1 on viral vector-mediated tumor therapy in immunocompetent mice Gene Therapy. 6: 1751-1758. PMID 10516725 DOI: 10.1038/  0.6
1999 Walker JR, McGeagh KG, Sundaresan P, Jorgensen TJ, Rabkin SD, Martuza RL. Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207. Human Gene Therapy. 10: 2237-43. PMID 10498254 DOI: 10.1089/10430349950017211  0.6
1999 Miyatake SI, Tani S, Feigenbaum F, Sundaresan P, Toda H, Narumi O, Kikuchi H, Hashimoto N, Hangai M, Martuza RL, Rabkin SD. Hepatoma-specific antitumor activity of an albumin enhancer/promoter regulated herpes simplex virus in vivo. Gene Therapy. 6: 564-72. PMID 10476216 DOI: 10.1038/  0.6
1999 Mashour GA, Wang HL, Cabal-Manzano R, Wellstein A, Martuza RL, Kurtz A. Aberrant cutaneous expression of the angiogenic factor midkine is associated with neurofibromatosis type-1. The Journal of Investigative Dermatology. 113: 398-402. PMID 10469340 DOI: 10.1046/j.1523-1747.1999.00699.x  0.6
1999 Hunter WD, Martuza RL, Feigenbaum F, Todo T, Mineta T, Yazaki T, Toda M, Newsome JT, Platenberg RC, Manz HJ, Rabkin SD. Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates. Journal of Virology. 73: 6319-26. PMID 10400723  0.6
1999 Toda M, Rabkin SD, Kojima H, Martuza RL. Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity. Human Gene Therapy. 10: 385-93. PMID 10048391 DOI: 10.1089/10430349950018832  0.6
1998 New KC, Gale K, Martuza RL, Rabkin SD. Novel synthesis and release of GABA in cerebellar granule cell cultures after infection with defective herpes simplex virus vectors expressing glutamic acid decarboxylase. Brain Research. Molecular Brain Research. 61: 121-35. PMID 9795182 DOI: 10.1016/S0169-328X(98)00203-4  0.6
1998 Toda M, Rabkin SD, Martuza RL. Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1. Human Gene Therapy. 9: 2177-85. PMID 9794202 DOI: 10.1089/hum.1998.9.15-2177  0.6
1998 Toda M, Martuza RL, Kojima H, Rabkin SD. In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity. Journal of Immunology (Baltimore, Md. : 1950). 160: 4457-64. PMID 9574551  0.6
1997 Martuza RL. Act locally, think globally. Nature Medicine. 3: 1323. PMID 9396599 DOI: 10.1038/nm1297-1323  0.6
1997 Miyatake S, Martuza RL, Rabkin SD. Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma. Cancer Gene Therapy. 4: 222-8. PMID 9253507  0.6
1997 Miyatake S, Iyer A, Martuza RL, Rabkin SD. Transcriptional targeting of herpes simplex virus for cell-specific replication. Journal of Virology. 71: 5124-32. PMID 9188579  0.6
1997 Menon AG, Rutter JL, von Sattel JP, Synder H, Murdoch C, Blumenfeld A, Martuza RL, von Deimling A, Gusella JF, Houseal TW. Frequent loss of chromosome 14 in atypical and malignant meningioma: identification of a putative 'tumor progression' locus. Oncogene. 14: 611-6. PMID 9053860 DOI: 10.1038/sj.onc.1200853  0.6
1996 Yazaki T, Martuza RL, Rabkin SD. Expression of L1 in primary astrocytes via a defective herpes simplex virus vector promotes neurite outgrowth and neural cell migration. Brain Research. Molecular Brain Research. 43: 311-20. PMID 9037547 DOI: 10.1016/S0169-328X(96)00186-6  0.6
1996 Viola JJ, Martuza RL. Gene therapies for glioblastomas. BaillièRe's Clinical Neurology. 5: 413-24. PMID 8781280  0.6
1996 Günel M, Awad IA, Finberg K, Steinberg GK, Craig HD, Cepeda O, Nelson-Williams C, Lifton RP. Genetic heterogeneity of inherited cerebral cavernous malformation. Neurosurgery. 38: 1265-71. PMID 8727164 DOI: 10.1097/00006123-199606000-00059  0.6
1996 Yazaki T, Ahmad S, Chahlavi A, Zylber-Katz E, Dean NM, Rabkin SD, Martuza RL, Glazer RI. Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide. Molecular Pharmacology. 50: 236-42. PMID 8700129  0.6
1995 Mineta T, Tabuchi K, Martuza RL. [Gene therapy for brain tumors: experimental treatment of malignant brain tumors using recombinant herpes simplex virus type 1 (series 7)]. No Shinkei Geka. Neurological Surgery. 23: 285-92. PMID 7739766  0.6
1995 Yazaki T, Manz HJ, Rabkin SD, Martuza RL. Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1. Cancer Research. 55: 4752-6. PMID 7585498  0.6
1995 Mineta T, Rabkin SD, Yazaki T, Hunter WD, Martuza RL. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nature Medicine. 1: 938-43. PMID 7585221  0.6
1995 Yazaki T, Takamiya Y, Costello PC, Mineta T, Menon AG, Rabkin SD, Martuza RL. Inhibition of angiogenesis and growth of human non-malignant and malignant meningiomas by TNP-470. Journal of Neuro-Oncology. 23: 23-9. PMID 7542695 DOI: 10.1007/BF01058456  0.6
1994 New KC, Martuza RL, Rabkin SD. Defective herpes simplex virus vectors for the study of promoter and gene function in the CNS. Gene Therapy. 1: S79. PMID 8542425  0.6
1994 Mineta T, Markert JM, Takamiya Y, Coen DM, Rabkin SD, Martuza RL. CNS tumor therapy by attenuated herpes simplex viruses. Gene Therapy. 1: S78. PMID 8542424  0.6
1994 Baer L, Rauch SL, Jenike MA, Cassem NH, Ballantine HT, Manzo PA, Martuza RL. Cingulotomy in a case of concomitant obsessive-compulsive disorder and Tourette's syndrome. Archives of General Psychiatry. 51: 73-4. PMID 8279932 DOI: 10.1001/archpsyc.1994.03950010073013  0.6
1994 Takamiya Y, Brem H, Ojeifo J, Mineta T, Martuza RL. AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo. Neurosurgery. 34: 869-75; discussion 8. PMID 8052385  0.6
1994 Mineta T, Rabkin SD, Martuza RL. Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant. Cancer Research. 54: 3963-6. PMID 8033122  0.6
1994 al-Nabulsi I, Takamiya Y, Voloshin Y, Dritschilo A, Martuza RL, Jorgensen TJ. Expression of thymidine kinase is essential to low dose radiation resistance of rat glioma cells. Cancer Research. 54: 5614-7. PMID 7923206  0.6
1994 Ahmad S, Mineta T, Martuza RL, Glazer RI. Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells. Neurosurgery. 35: 904-8; discussion 90. PMID 7838340  0.6
1993 Trofatter JA, MacCollin MM, Rutter JL, Murrell JR, Duyao MP, Parry DM, Eldridge R, Kley N, Menon AG, Pulaski K. A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell. 72: 791-800. PMID 8453669 DOI: 10.1016/0092-8674(93)90406-G  0.6
1993 Takamiya Y, Friedlander RM, Brem H, Malick A, Martuza RL. Inhibition of angiogenesis and growth of human nerve-sheath tumors by AGM-1470. Journal of Neurosurgery. 78: 470-6. PMID 8433151 DOI: 10.3171/jns.1993.78.3.0470  0.6
1993 Takamiya Y, Short MP, Moolten FL, Fleet C, Mineta T, Breakefield XO, Martuza RL. An experimental model of retrovirus gene therapy for malignant brain tumors. Journal of Neurosurgery. 79: 104-10. PMID 8391069 DOI: 10.3171/jns.1993.79.1.0104  0.6
1993 Markert JM, Malick A, Coen DM, Martuza RL. Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir. Neurosurgery. 32: 597-603. PMID 8386343  0.6
1993 Yu JS, Wei MX, Chiocca EA, Martuza RL, Tepper RI. Treatment of glioma by engineered interleukin 4-secreting cells. Cancer Research. 53: 3125-8. PMID 8319220  0.6
1992 Poon WS, Schomacker KT, Deutsch TF, Martuza RL. Laser-induced fluorescence: experimental intraoperative delineation of tumor resection margins. Journal of Neurosurgery. 76: 679-86. PMID 1545262 DOI: 10.3171/jns.1992.76.4.0679  0.6
1992 Narod SA, Parry DM, Parboosingh J, Lenoir GM, Ruttledge M, Fischer G, Eldridge R, Martuza RL, Frontali M, Haines J. Neurofibromatosis type 2 appears to be a genetically homogeneous disease. American Journal of Human Genetics. 51: 486-96. PMID 1496982  0.6
1992 Lee JK, Sobel RA, Chiocca EA, Kim TS, Martuza RL. Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse. Journal of Neuro-Oncology. 14: 101-12. PMID 1432035 DOI: 10.1007/BF00177613  0.6
1992 Nadol JB, Chiong CM, Ojemann RG, McKenna MJ, Martuza RL, Montgomery WW, Levine RA, Ronner SF, Glynn RJ. Preservation of hearing and facial nerve function in resection of acoustic neuroma. The Laryngoscope. 102: 1153-8. PMID 1405966 DOI: 10.1288/00005537-199210000-00010  0.6
1992 Martuza RL. Molecular neurosurgery for glial and neuronal disorders. Stereotactic and Functional Neurosurgery. 59: 92-9. PMID 1338233 DOI: 10.1159/000098923  0.6
1992 Takamiya Y, Short MP, Ezzeddine ZD, Moolten FL, Breakefield XO, Martuza RL. Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells. Journal of Neuroscience Research. 33: 493-503. PMID 1335091 DOI: 10.1002/jnr.490330316  0.6
1992 Markert JM, Coen DM, Malick A, Mineta T, Martuza RL. Expanded spectrum of viral therapy in the treatment of nervous system tumors. Journal of Neurosurgery. 77: 590-4. PMID 1326612 DOI: 10.3171/jns.1992.77.4.0590  0.6
1992 von Deimling A, Louis DN, von Ammon K, Petersen I, Hoell T, Chung RY, Martuza RL, Schoenfeld DA, YaÅŸargil MG, Wiestler OD. Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. Journal of Neurosurgery. 77: 295-301. PMID 1320666 DOI: 10.3171/jns.1992.77.2.0295  0.6
1992 Huang Q, Vonsattel JP, Schaffer PA, Martuza RL, Breakefield XO, DiFiglia M. Introduction of a foreign gene (Escherichia coli lacZ) into rat neostriatal neurons using herpes simplex virus mutants: a light and electron microscopic study. Experimental Neurology. 115: 303-16. PMID 1311266 DOI: 10.1016/0014-4886(92)90196-W  0.6
1991 Jenike MA, Baer L, Ballantine T, Martuza RL, Tynes S, Giriunas I, Buttolph ML, Cassem NH. Cingulotomy for refractory obsessive-compulsive disorder. A long-term follow-up of 33 patients. Archives of General Psychiatry. 48: 548-55. PMID 2039338 DOI: 10.1001/archpsyc.1991.01810300060009  0.6
1991 Fontaine B, Rouleau GA, Seizinger BR, Menon AG, Jewell AF, Martuza RL, Gusella JF. Molecular genetics of neurofibromatosis 2 and related tumors (acoustic neuroma and meningioma). Annals of the New York Academy of Sciences. 615: 338-43. PMID 2039155  0.6
1991 Fontaine B, Hanson MP, VonSattel JP, Martuza RL, Gusella JF. Loss of chromosome 22 alleles in human sporadic spinal schwannomas. Annals of Neurology. 29: 183-6. PMID 2012386 DOI: 10.1002/ana.410290211  0.6
1991 Seizinger BR, Smith DI, Filling-Katz MR, Neumann H, Green JS, Choyke PL, Anderson KM, Freiman RN, Klauck SM, Whaley J. Genetic flanking markers refine diagnostic criteria and provide insights into the genetics of Von Hippel Lindau disease. Proceedings of the National Academy of Sciences of the United States of America. 88: 2864-8. PMID 2011596  0.6
1991 Steichen JD, Weiss MJ, Elmaleh DR, Martuza RL. Enhanced in vitro uptake and retention of 3H-tetraphenylphosphonium by nervous system tumor cells. Journal of Neurosurgery. 74: 116-22. PMID 1984490 DOI: 10.3171/jns.1991.74.1.0116  0.6
1991 Flexon PB, Nadol JB, Schuknecht HF, Montgomery WW, Martuza RL. Bilateral acoustic neurofibromatosis (neurofibromatosis 2): a disorder distinct from von Recklinghausen's neurofibromatosis (neurofibromatosis 1). The Annals of Otology, Rhinology, and Laryngology. 100: 830-4. PMID 1952650  0.6
1991 Martuza RL, Malick A, Markert JM, Ruffner KL, Coen DM. Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science (New York, N.Y.). 252: 854-6. PMID 1851332  0.6
1991 Halliday AL, Sobel RA, Martuza RL. Benign spinal nerve sheath tumors: their occurrence sporadically and in neurofibromatosis types 1 and 2. Journal of Neurosurgery. 74: 248-53. PMID 1846409 DOI: 10.3171/jns.1991.74.2.0248  0.6
1991 Fontaine B, Sanson M, Delattre O, Menon AG, Rouleau GA, Seizinger BR, Jewell AF, Hanson MP, Aurias A, Martuza RL. Parental origin of chromosome 22 loss in sporadic and NF2 neuromas. Genomics. 10: 280-3. PMID 1675196 DOI: 10.1016/0888-7543(91)90513-E  0.6
1991 Ezzeddine ZD, Martuza RL, Platika D, Short MP, Malick A, Choi B, Breakefield XO. Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. The New Biologist. 3: 608-14. PMID 1655012  0.6
1990 Steichen JD, Stewart RB, Louis DN, Choi BB, Kung R, Martuza RL. A new 1.9-mu wavelength laser for neurosurgery. Journal of Neurosurgery. 73: 611-4. PMID 2398391 DOI: 10.3171/jns.1990.73.4.0611  0.6
1990 Lee JK, Kim TS, Chiocca EA, Medhkour A, Martuza RL. Growth of human schwannomas in the subrenal capsule of the nude mouse. Neurosurgery. 26: 598-605. PMID 2330081  0.6
1990 Logan JA, Seizinger BR, Atkins L, Martuza RL. Loss of the Y chromosome in meningiomas. A molecular genetic approach. Cancer Genetics and Cytogenetics. 45: 41-7. PMID 2302684 DOI: 10.1016/0165-4608(90)90064-H  0.6
1990 Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma: a follow-up study of sarcomatous dedifferentiation. Acta Neuropathologica. 80: 573-4. PMID 2251917 DOI: 10.1007/BF00294623  0.6
1990 Fontaine B, Rouleau GA, Seizinger B, Jewell AF, Hanson MP, Martuza RL, Gusella JF. Equal parental origin of chromosome 22 losses in human sporadic meningioma: no evidence for genomic imprinting. American Journal of Human Genetics. 47: 823-7. PMID 2220822  0.6
1990 Jacoby LB, Hedley-Whyte ET, Pulaski K, Seizinger BR, Martuza RL. Clonal origin of pituitary adenomas. Journal of Neurosurgery. 73: 731-5. PMID 2213163 DOI: 10.3171/jns.1990.73.5.0731  0.6
1990 Jacoby LB, Pulaski K, Rouleau GA, Martuza RL. Clonal analysis of human meningiomas and schwannomas. Cancer Research. 50: 6783-6. PMID 2208143  0.6
1990 Chiocca EA, Choi BB, Cai WZ, DeLuca NA, Schaffer PA, DiFiglia M, Breakefield XO, Martuza RL. Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants. The New Biologist. 2: 739-46. PMID 2178004  0.6
1990 Menon AG, Anderson KM, Riccardi VM, Chung RY, Whaley JM, Yandell DW, Farmer GE, Freiman RN, L-Ee JK, Li FP, Barker DF, Ledbetter DH, Kleider A, Martuza RL, Gusella JF, et al. Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis Proceedings of the National Academy of Sciences of the United States of America. 87: 5435-5439. PMID 2142531  0.6
1990 Martuza RL, Chiocca EA, Jenike MA, Giriunas IE, Ballantine HT. Stereotactic radiofrequency thermal cingulotomy for obsessive compulsive disorder. The Journal of Neuropsychiatry and Clinical Neurosciences. 2: 331-6. PMID 2136095  0.6
1990 Short MP, Choi BC, Lee JK, Malick A, Breakefield XO, Martuza RL. Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line. Journal of Neuroscience Research. 27: 427-39. PMID 2129047 DOI: 10.1002/jnr.490270322  0.6
1990 Rouleau GA, Seizinger BR, Wertelecki W, Haines JL, Superneau DW, Martuza RL, Gusella JF. Flanking markers bracket the neurofibromatosis type 2 (NF2) gene on chromosome 22. American Journal of Human Genetics. 46: 323-8. PMID 2105641  0.6
1990 Lee JK, Choi B, Sobel RA, Chiocca EA, Martuza RL. Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone. Journal of Neurosurgery. 73: 429-35. PMID 1696626 DOI: 10.3171/jns.1990.73.3.0429  0.6
1990 Martuza RL. Pathogenesis and treatment of nervous system tumors in NF2 Tuberous Sclerosis and Neurofibromatosis: Epidemiology, Pathophysiology, Biology and Management: Proceedings of the International Symposium On Neurocutaneous Syndrome. Ics882. 281-287.  0.6
1989 Louis DN, Hedley-Whyte ET, Martuza RL. Sarcomatous proliferation of the vasculature in a subependymoma. Acta Neuropathologica. 78: 332-5. PMID 2763807 DOI: 10.1007/BF00687765  0.6
1989 el-Azouzi M, Chung RY, Farmer GE, Martuza RL, Black PM, Rouleau GA, Hettlich C, Hedley-Whyte ET, Zervas NT, Panagopoulos K. Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas. Proceedings of the National Academy of Sciences of the United States of America. 86: 7186-90. PMID 2571151  0.6
1989 Seizinger BR, Farmer GE, Haines JL, Ozelius LJ, Anderson K, Korf BR, Parry DM, Pericak-Vance MA, Mulvihill JJ, Menon A. Flanking markers for the gene causing von Recklinghausen neurofibromatosis (NF1). American Journal of Human Genetics. 44: 30-2. PMID 2491778  0.6
1989 Medhkour A, Van Roey M, Sobel RA, Fingert HJ, Lee J, Martuza RL. Implantation of human meningiomas into the subrenal capsule of the nude mouse. A model for studies of tumor growth. Journal of Neurosurgery. 71: 545-50. PMID 2477514 DOI: 10.3171/jns.1989.71.4.0545  0.6
1988 Martuza RL, Eldridge R. Neurofibromatosis 2 (bilateral acoustic neurofibromatosis). The New England Journal of Medicine. 318: 684-8. PMID 3125435 DOI: 10.1056/NEJM198803173181106  0.6
1988 Kostron H, Swartz MR, Martuza RL. Photodynamic therapy is potentiated by Co60 and intratumoral injection of hematoporphyrin derivative. Journal of Neuro-Oncology. 6: 185-91. PMID 2976084 DOI: 10.1007/BF02327395  0.6
1988 Seizinger BR, Rouleau GA, Ozelius LJ, Lane AH, Farmer GE, Lamiell JM, Haines J, Yuen JW, Collins D, Majoor-Krakauer D. Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma. Nature. 332: 268-9. PMID 2894613 DOI: 10.1038/332268a0  0.6
1988 Martuza RL, Seizinger BR, Jacoby LB, Rouleau GA, Gusella JF. The molecular biology of human glial tumors. Trends in Neurosciences. 11: 22-7. PMID 2469150 DOI: 10.1016/0166-2236(88)90045-8  0.6
1987 Nadol JB, Levine R, Ojemann RG, Martuza RL, Montgomery WW, de Sandoval PK. Preservation of hearing in surgical removal of acoustic neuromas of the internal auditory canal and cerebellar pontine angle. The Laryngoscope. 97: 1287-94. PMID 3499554 DOI: 10.1288/00005537-198711000-00007  0.6
1987 Seizinger BR, Martuza RL, Rouleau G, Breakefield XO, Gusella JF. Models for inherited susceptibility to cancer in the nervous system: a molecular-genetic approach to neurofibromatosis. Developmental Neuroscience. 9: 144-53. PMID 3119309 DOI: 10.1159/000111618  0.6
1987 Seizinger BR, Rouleau G, Ozelius LJ, Lane AH, St George-Hyslop P, Huson S, Gusella JF, Martuza RL. Common pathogenetic mechanism for three tumor types in bilateral acoustic neurofibromatosis. Science (New York, N.Y.). 236: 317-9. PMID 3105060  0.6
1987 Seizinger BR, de la Monte S, Atkins L, Gusella JF, Martuza RL. Molecular genetic approach to human meningioma: loss of genes on chromosome 22. Proceedings of the National Academy of Sciences of the United States of America. 84: 5419-23. PMID 3037550  0.6
1987 Seizinger BR, Rouleau GA, Lane AH, Farmer G, Ozelius LJ, Haines JL, Parry DM, Korf BR, Pericak-Vance MA, Faryniarz AG, Hobbs WJ, Iannazzi JA, Roy JC, Menon A, Bader JL, ... ... Martuza RL, et al. Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17 Genomics. 1: 346-348. PMID 2896628 DOI: 10.1016/0888-7543(87)90035-8  0.6
1987 Rouleau GA, Wertelecki W, Haines JL, Hobbs WJ, Trofatter JA, Seizinger BR, Martuza RL, Superneau DW, Conneally PM, Gusella JF. Genetic linkage of bilateral acoustic neurofibromatosis to a DNA marker on chromosome 22. Nature. 329: 246-8. PMID 2888021 DOI: 10.1038/329246a0  0.6
1987 Seizinger BR, Rouleau GA, Ozelius LJ, Lane AH, Faryniarz AG, Chao MV, Huson S, Korf BR, Parry DM, Pericak-Vance MA. Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene. Cell. 49: 589-94. PMID 2884037 DOI: 10.1016/0092-8674(87)90534-4  0.6
1986 Kostron H, Swartz MR, Miller DC, Martuza RL. The interaction of hematoporphyrin derivative, light, and ionizing radiation in a rat glioma model. Cancer. 57: 964-70. PMID 3943032  0.6
1986 Brockes JP, Breakefield XO, Martuza RL. Glial growth factor-like activity in Schwann cell tumors. Annals of Neurology. 20: 317-22. PMID 3767316 DOI: 10.1002/ana.410200308  0.6
1986 Fitzpatrick TB, Martuza RL. Clinical diagnosis of von Recklinghausen's neurofibromatosis. Annals of the New York Academy of Sciences. 486: 383-5. PMID 3105402  0.6
1986 Seizinger BR, Martuza RL, Gusella JF. Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma. Nature. 322: 644-7. PMID 3092103 DOI: 10.1038/322644a0  0.6
1986 Jacoby LB, Martuza RL. DNA transfection analysis of the tumors of neurofibromatosis. Annals of the New York Academy of Sciences. 486: 333-5. PMID 3032057  0.6
1986 Steichen JD, Dashner K, Martuza RL. Distribution of hematoporphyrin derivative in canine glioma following intraneoplastic and intraperitoneal injection. Journal of Neurosurgery. 65: 364-9. PMID 2942650 DOI: 10.3171/jns.1986.65.3.0364  0.6
1986 Kostron H, Bellnier DA, Lin CW, Swartz MR, Martuza RL. Distribution, retention, and phototoxicity of hematoporphyrin derivative in a rat glioma. Intraneoplastic versus intraperitoneal injection. Journal of Neurosurgery. 64: 768-74. PMID 2939204 DOI: 10.3171/jns.1986.64.5.0768  0.6
1985 Jay JR, MacLaughlin DT, Riley KR, Martuza RL. Modulation of meningioma cell growth by sex steroid hormones in vitro. Journal of Neurosurgery. 62: 757-62. PMID 3989596 DOI: 10.3171/jns.1985.62.5.0757  0.6
1985 Martuza RL, Miller DC, MacLaughlin DT. Estrogen and progestin binding by cytosolic and nuclear fractions of human meningiomas. Journal of Neurosurgery. 62: 750-6. PMID 3989595 DOI: 10.3171/jns.1985.62.5.0750  0.6
1985 Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL. Meningioma: analysis of recurrence and progression following neurosurgical resection. Journal of Neurosurgery. 62: 18-24. PMID 3964853 DOI: 10.3171/jns.1985.62.1.0018  0.6
1985 Martuza RL, Parker SW, Nadol JB, Davis KR, Ojemann RG. Diagnosis of cerebellopontine angle tumors. Clinical Neurosurgery. 32: 177-213. PMID 3933874  0.6
1985 Martuza RL, Philippe I, Fitzpatrick TB, Zwaan J, Seki Y, Lederman J. Melanin macroglobules as a cellular marker of neurofibromatosis: a quantitative study. The Journal of Investigative Dermatology. 85: 347-50. PMID 3930616  0.6
1985 Granick MS, Martuza RL, Parker SW, Ojemann RG, Montgomery WW. Cerebellopontine angle meningiomas: clinical manifestations and diagnosis. The Annals of Otology, Rhinology, and Laryngology. 94: 34-8. PMID 3871599  0.6
1984 Nakagawa H, Hori Y, Sato S, Fitzpatrick TB, Martuza RL. The nature and origin of the melanin macroglobule. The Journal of Investigative Dermatology. 83: 134-9. PMID 6432917  0.6
1983 Martuza RL. Genetics in neuro-oncology. Clinical Neurosurgery. 31: 417-40. PMID 6437720  0.6
1982 Martuza RL, Ojemann RG. Bilateral acoustic neuromas: clinical aspects, pathogenesis, and treatment. Neurosurgery. 10: 1-12. PMID 7057963  0.6
1982 Conner ES, Martuza RL, Heros RC. Seizures due to metrizamide myelography in patients with acute cervical spine injury. Neurosurgery. 10: 266-7. PMID 6803187  0.6
1982 Martuza RL, Liszczak T, Okun A, Wang TY. HUMAN NEUROFIBROMAS IN CO-CULTURE WITH MOUSE NEURONS Proceedings - Electron Microscopy Society of America. 194-195.  0.6
1981 Chapman PH, Martuza RL, Poletti CE, Karchmer AW. Symptomatic spinal epidural lipomatosis associated with Cushing's syndrome. Neurosurgery. 8: 724-7. PMID 7279161  0.6
1981 Martuza RL, Ojemann RG, Shillito J, Wepsic JG. Facial pain associated with a middle fossa arachnoid cyst. Neurosurgery. 8: 712-16. PMID 7279159  0.6
1981 Martuza RL, MacLaughlin DT, Ojemann RG. Specific estradiol binding in schwannomas, meningiomas, and neurofibromas. Neurosurgery. 9: 665-71. PMID 7198726  0.6
1977 Martuza RL, Kornblith PL, Liszczak TM. Characteristics of human optic gliomas in tissue culture. Journal of Neurosurgery. 46: 78-84. PMID 830817 DOI: 10.3171/jns.1977.46.1.0078  0.6
1976 Stewart RM, Martuza RL, Baldessarini RJ, Kornblith PL. Glutamate accumulation by human gliomas and meningiomas in tissue culture. Brain Research. 118: 441-52. PMID 1009428 DOI: 10.1016/0006-8993(76)90311-5  0.6
1976 Phillips JP, Sujatanond M, Martuza RL, Quindlen EA, Wood WC, Kornblith PL, Dohan FC. Cytotoxic antibodies in preoperative glioma patients: a diagnostic assay. Acta Neurochirurgica. 35: 43-52. PMID 961503 DOI: 10.1007/BF01405931  0.6
1976 Martuza RL, Proffitt MR, Moore MB, Dohan CF. Evaporation as a cause of positional differences in cell plating and growth in microtiter plates. Transplantation. 21: 271-3. PMID 941215  0.6
1975 Martuza RL, Shamberger RC, Phillips JP, Kornblith PL, Dohan FC, Hochberg FH. A lymphocyte-dependent antibody assay for detection of antibodies to human glioma cells. Surgical Forum. 26: 492-4. PMID 175519  0.6
1973 Martuza RL, Black PH, Kornblith PL, Dohan FC. Evidence for presence of a virus in glioblastoma multiforme cells. Surgical Forum. 24: 459-61. PMID 4377039  0.6
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