Yutaka Kawakami - Publications

Affiliations: 
Keio University, Minato-ku, Tōkyō-to, Japan 

280 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ohta S, Misawa A, Kyi-Tha-Thu C, Matsumoto N, Hirose Y, Kawakami Y. Melanoma antigens recognized by T cells and their use for immunotherapy. Experimental Dermatology. PMID 36607252 DOI: 10.1111/exd.14741  0.36
2022 Morimoto Y, Tokumitsu A, Sone T, Hirota Y, Tamura R, Sakamoto A, Nakajima K, Toda M, Kawakami Y, Okano H, Ohta S. TPT1 Supports Proliferation of Neural Stem/Progenitor Cells and Brain Tumor Initiating Cells Regulated by Macrophage Migration Inhibitory Factor (MIF). Neurochemical Research. PMID 35622214 DOI: 10.1007/s11064-022-03629-6  0.474
2022 Wang B, Xu Z, Sunthamala N, Yaguchi T, Huang J, Kawakami Y, Gong Y, Tang H, Li S, Guo Y, Guo Y, Jinushi M. Combinatorial sympathetic and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) blockades inhibit the murine melanoma growth by targeting infiltrating T cells. Translational Cancer Research. 10: 899-913. PMID 35116419 DOI: 10.21037/tcr-20-2738  0.313
2021 Fukuda K, Okamura K, Riding RL, Fan X, Afshari K, Haddadi NS, McCauley SM, Guney MH, Luban J, Funakoshi T, Yaguchi T, Kawakami Y, Khvorova A, Fitzgerald KA, Harris JE. AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma. The Journal of Experimental Medicine. 218. PMID 34325468 DOI: 10.1084/jem.20200962  0.32
2021 Hirai I, Funakoshi T, Kamijuku H, Fukuda K, Mori M, Sakurai M, Koda Y, Kato J, Mori T, Watanabe N, Noji S, Yaguchi T, Iwata T, Ohta S, Fujita T, ... ... Kawakami Y, et al. Adoptive cell therapy using tumor-infiltrating lymphocytes for melanoma refractory to immune-checkpoint inhibitors. Cancer Science. PMID 34101300 DOI: 10.1111/cas.15009  0.302
2021 Kinoshita T, Sayem MA, Yaguchi T, Kharma B, Morii K, Kato D, Ohta S, Mashima Y, Asamura H, Kawakami Y. Inhibition of vascular adhesion protein-1 enhances the anti-tumor effects of immune checkpoint inhibitors. Cancer Science. PMID 33453147 DOI: 10.1111/cas.14812  0.321
2021 Yamada K, Hazama S, Suzuki N, Xu M, Nakagami Y, Fujiwara N, Tsunedomi R, Yoshida S, Tomochika S, Matsukuma S, Matsui H, Tokumitsu Y, Kanekiyo S, Shindo Y, Watanabe Y, ... ... Kawakami Y, et al. Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer. Oncology Letters. 21: 10. PMID 33240416 DOI: 10.3892/ol.2020.12271  0.308
2020 Hayakawa T, Yaguchi T, Kawakami Y. Enhanced anti-tumor effects of the PD-1 blockade combined with a highly absorptive form of curcumin targeting STAT3. Cancer Science. PMID 33006786 DOI: 10.1111/cas.14675  0.33
2020 Sugihara E, Hashimoto N, Osuka S, Shimizu T, Ueno S, Okazaki S, Yaguchi T, Kawakami Y, Kosaki K, Sato TA, Okamoto S, Saya H. The inhibitor of apoptosis protein Livin confers resistance to Fas-mediated immune cytotoxicity in refractory lymphoma. Cancer Research. PMID 32928920 DOI: 10.1158/0008-5472.CAN-19-3993  0.353
2020 Ohno A, Iwata T, Katoh Y, Taniguchi S, Tanaka K, Nishio H, Nakamura M, Morisada T, Chen G, Saito M, Yaguchi T, Kawakami Y, Aoki D. Tumor-infiltrating lymphocytes predict survival outcomes in patients with cervical cancer treated with concurrent chemoradiotherapy. Gynecologic Oncology. PMID 32829964 DOI: 10.1016/j.ygyno.2020.07.106  0.37
2020 Kinoshita T, Kawakami Y. Interface of cancer stem cells and cancer immunity. Annals of Translational Medicine. 8: 810. PMID 32793655 DOI: 10.21037/atm.2020.04.08  0.332
2020 Yamane M, Sato S, Shimizu E, Shibata S, Hayano M, Yaguchi T, Kamijuku H, Ogawa M, Suzuki T, Mukai S, Shimmura S, Okano H, Takeuchi T, Kawakami Y, Ogawa Y, et al. Senescence-associated secretory phenotype promotes chronic ocular graft-vs-host disease in mice and humans. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32619061 DOI: 10.1096/Fj.201900218R  0.332
2020 Tamura R, Fujioka M, Morimoto Y, Ohara K, Kosugi K, Oishi Y, Sato M, Ueda R, Fujiwara H, Hikichi T, Noji S, Oishi N, Ogawa K, Kawakami Y, Ohira T, et al. Author Correction: A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2. Nature Communications. 11: 2028. PMID 32317644 DOI: 10.1038/S41467-020-16007-Z  0.414
2020 Tamura R, Morimoto Y, Kosugi K, Sato M, Oishi Y, Ueda R, Kikuchi R, Nagashima H, Hikichi T, Noji S, Kawakami Y, Sasaki H, Yoshida K, Toda M. Correction to: Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series. Bmc Cancer. 20: 301. PMID 32290821 DOI: 10.1186/s12885-020-06783-8  0.43
2020 Kato D, Yaguchi T, Iwata T, Katoh Y, Morii K, Tsubota K, Takise Y, Tamiya M, Kamada H, Akiba H, Tsumoto K, Serada S, Naka T, Nishimura R, Nakagawa T, ... Kawakami Y, et al. GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab. Elife. 9. PMID 32228854 DOI: 10.7554/eLife.49392  0.434
2020 Tamura R, Morimoto Y, Kosugi K, Sato M, Oishi Y, Ueda R, Kikuchi R, Nagashima H, Noji S, Kawakami Y, Sasaki H, Yoshida K, Toda M. Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series. Bmc Cancer. 20: 196. PMID 32164575 DOI: 10.1186/s12885-020-6589-x  0.529
2020 Kiyohara E, Tanemura A, Nishioka M, Yamada M, Tanaka A, Yokomi A, Saito A, Sakura K, Nakajima T, Myoui A, Sakurai T, Kawakami Y, Kaneda Y, Katayama I. Intratumoral injection of hemagglutinating virus of Japan-envelope vector yielded an antitumor effect for advanced melanoma: a phase I/IIa clinical study. Cancer Immunology, Immunotherapy : Cii. PMID 32047956 DOI: 10.1007/s00262-020-02509-8  0.383
2020 Al-Busani H, Al-Sobaihi S, Nojima K, Tanemura A, Yaguchi T, Kawakami Y, Matsumura H, Nishimura EK, Yokozeki H, Namiki T. NUAK2 localization in normal skin and its expression in a variety of skin tumors with YAP. Journal of Dermatological Science. 97: 143-151. PMID 32001115 DOI: 10.1016/j.jdermsci.2020.01.008  0.315
2020 Kawakami Y, Ohta S, Sayem MA, Tsukamoto N, Yaguchi T. Immune-resistant mechanisms in cancer immunotherapy. International Journal of Clinical Oncology. PMID 31919690 DOI: 10.1007/s10147-019-01611-x  0.389
2020 Kato D, Yaguchi T, Iwata T, Katoh Y, Morii K, Tsubota K, Takise Y, Tamiya M, Kamada H, Akiba H, Tsumoto K, Serada S, Naka T, Nishimura R, Nakagawa T, ... Kawakami Y, et al. Author response: GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab Elife. DOI: 10.7554/Elife.49392.Sa2  0.357
2020 Galon J, Hermitte F, Mlecnik B, Lugli A, Bifulco CB, Nagtegaal ID, Hartmann A, Marliot F, Van Den Eynde M, Roehrl MHA, Ohashi PS, Zavadova E, Torigoe T, Patel PS, Wang Y, ... Kawakami Y, et al. Immunoscore as a parameter predicting time to recurrence and disease-free survival in T4N0 stage II colon cancer patients. Journal of Clinical Oncology. 38: 4105-4105. DOI: 10.1200/jco.2020.38.15_suppl.4105  0.3
2019 Tamura R, Fujioka M, Morimoto Y, Ohara K, Kosugi K, Oishi Y, Sato M, Ueda R, Fujiwara H, Noji S, Oishi N, Ogawa K, Kawakami Y, Ohira T, Yoshida K, et al. A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2. Nature Communications. 10: 5758. PMID 31848332 DOI: 10.1038/S41467-019-13640-1  0.517
2019 Kuwahara T, Hazama S, Suzuki N, Yoshida S, Tomochika S, Nakagami Y, Matsui H, Shindo Y, Kanekiyo S, Tokumitsu Y, Iida M, Tsunedomi R, Takeda S, Yoshino S, Okayama N, ... ... Kawakami Y, et al. Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer. British Journal of Cancer. PMID 31488881 DOI: 10.1038/s41416-019-0559-6  0.336
2019 Osawa Y, Kojika E, Nishikawa K, Kimura M, Osakaya S, Miyauchi H, Kanto T, Kawakami Y, Kimura K. Programmed cell death ligand 1 (PD-L1) blockade attenuates metastatic colon cancer growth in cAMP-response element-binding protein (CREB)-binding protein (CBP)/β-catenin inhibitor-treated livers. Oncotarget. 10: 3013-3026. PMID 31105882 DOI: 10.18632/oncotarget.26892  0.377
2019 Kikuchi R, Ueda R, Saito K, Shibao S, Nagashima H, Tamura R, Morimoto Y, Sasaki H, Noji S, Kawakami Y, Yoshida K, Toda M. A Pilot Study of Vaccine Therapy with Multiple Glioma Oncoantigen/Glioma Angiogenesis-Associated Antigen Peptides for Patients with Recurrent/Progressive High-Grade Glioma. Journal of Clinical Medicine. 8. PMID 30791546 DOI: 10.3390/jcm8020263  0.515
2019 Nakamura Y, Tanese K, Hirai I, Amagai M, Kawakami Y, Funakoshi T. Serum cytokeratin 19 fragment 21-1 and carcinoembryonic antigen combination assay as a biomarker of tumour progression and treatment response in extramammary Paget disease. British Journal of Dermatology. 181: 535-543. PMID 30791097 DOI: 10.1111/Bjd.17789  0.305
2019 Inozume T, Yaguchi T, Ariyasu R, Togashi Y, Ohnuma T, Honobe A, Nishikawa H, Kawakami Y, Kawamura T. Analysis of the tumor reactivity of tumor-infiltrating lymphocytes in a metastatic melanoma lesion that lost MHC class I expression after anti-PD-1 therapy. The Journal of Investigative Dermatology. PMID 30684558 DOI: 10.1016/j.jid.2019.01.007  0.4
2019 Tanoue T, Morita S, Plichta DR, Skelly AN, Suda W, Sugiura Y, Narushima S, Vlamakis H, Motoo I, Sugita K, Shiota A, Takeshita K, Yasuma-Mitobe K, Riethmacher D, Kaisho T, ... ... Kawakami Y, et al. A defined commensal consortium elicits CD8 T cells and anti-cancer immunity. Nature. PMID 30675064 DOI: 10.1038/S41586-019-0878-Z  0.334
2019 Kimura K, Osawa Y, Nishikawa K, Kimura M, Kawakami Y. PD-1/PD-L1 immune check points blockade to attenuate growth of metastatic colon cancer in the CBP/β-catenin inhibited liver. Journal of Clinical Oncology. 37: 556-556. DOI: 10.1200/jco.2019.37.4_suppl.556  0.36
2018 Kawakami Y. [Personalized modulation of tumor microimmune microenvironment for the development of effective combination immunotherapy]. [Rinsho Ketsueki] the Japanese Journal of Clinical Hematology. 59: 939-944. PMID 30078806 DOI: 10.11406/rinketsu.59.939  0.37
2018 Nakamura Y, Tanese K, Hirai I, Kawakami Y, Funakoshi T. Carboplatin and epirubicin combination therapy for advanced malignant epithelial skin tumors: Retrospective study of six patients. The Journal of Dermatology. 45: 874-875. PMID 29971836 DOI: 10.1111/1346-8138.14328  0.336
2018 Matsuda T, Takeuchi H, Sakurai T, Mayanagi S, Booka E, Fujita T, Higuchi H, Taguchi J, Hamamoto Y, Takaishi H, Kawakubo H, Okamoto M, Sunamura M, Kawakami Y, Kitagawa Y. Pilot study of WT1 peptide-pulsed dendritic cell vaccination with docetaxel in esophageal cancer. Oncology Letters. 16: 1348-1356. PMID 29963201 DOI: 10.3892/ol.2018.8734  0.407
2018 Shibao S, Ueda R, Saito K, Kikuchi R, Nagashima H, Kojima A, Kagami H, Pareira ES, Sasaki H, Noji S, Kawakami Y, Yoshida K, Toda M. A pilot study of peptide vaccines for VEGF receptor 1 and 2 in patients with recurrent/progressive high grade glioma. Oncotarget. 9: 21569-21579. PMID 29765561 DOI: 10.18632/oncotarget.25131  0.482
2018 Pagès F, Mlecnik B, Marliot F, Bindea G, Ou FS, Bifulco C, Lugli A, Zlobec I, Rau TT, Berger MD, Nagtegaal ID, Vink-Börger E, Hartmann A, Geppert C, Kolwelter J, ... ... Kawakami Y, et al. International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study. Lancet (London, England). PMID 29754777 DOI: 10.1016/S0140-6736(18)30789-X  0.367
2018 Kamamoto D, Ohara K, Kitamura Y, Yoshida K, Kawakami Y, Sasaki H. Association between programmed cell death ligand-1 expression and extracranial metastasis in intracranial solitary fibrous tumor/hemangiopericytoma. Journal of Neuro-Oncology. PMID 29675794 DOI: 10.1007/s11060-018-2876-7  0.38
2018 Hegab AE, Ozaki M, Kagawa S, Hamamoto J, Yasuda H, Naoki K, Soejima K, Yin Y, Kinoshita T, Yaguchi T, Kawakami Y, Ornitz DM, Betsuyaku T. Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms. Lung Cancer (Amsterdam, Netherlands). 119: 25-35. PMID 29656749 DOI: 10.1016/J.Lungcan.2018.02.015  0.337
2018 Kanekiyo S, Hazama S, Takenouchi H, Nakajima M, Shindo Y, Matsui H, Tokumitsu Y, Tomochika S, Tsunedomi R, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, ... ... Kawakami Y, et al. IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides. Oncology Reports. PMID 29498403 DOI: 10.3892/or.2018.6288  0.36
2018 Hanazawa A, Ito R, Katano I, Kawai K, Goto M, Suemizu H, Kawakami Y, Ito M, Takahashi T. Generation of Human Immunosuppressive Myeloid Cell Populations in Human Interleukin-6 Transgenic NOG Mice. Frontiers in Immunology. 9: 152. PMID 29456539 DOI: 10.3389/fimmu.2018.00152  0.419
2018 Galon J, Mlecnik B, Hermitte F, Marliot F, Bifulco C, Lugli A, Nagtegaal I, Hartmann A, van den Eynde M, Roehrl M, Ohashi P, Zavadova E, Torigoe T, Patel P, Wang Y, ... Kawakami Y, et al. MSI status plus immunoscore to select metastatic colorectal cancer patients for immunotherapies Annals of Oncology. 29: x4. DOI: 10.1093/Annonc/Mdy493.011  0.303
2017 Katano I, Nishime C, Ito R, Kamisako T, Mizusawa T, Ka Y, Ogura T, Suemizu H, Kawakami Y, Ito M, Takahashi T. Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse. Scientific Reports. 7: 17230. PMID 29222435 DOI: 10.1038/s41598-017-17442-7  0.374
2017 Yaguchi T, Kobayashi A, Inozume T, Morii K, Nagumo H, Nishio H, Iwata T, Ka Y, Katano I, Ito R, Ito M, Kawakami Y. Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses. Cellular & Molecular Immunology. PMID 29151581 DOI: 10.1038/cmi.2017.106  0.441
2017 Nakamura K, Yaguchi T, Ohmura G, Kobayashi A, Kawamura N, Iwata T, Kiniwa Y, Okuyama R, Kawakami Y. Involvement of local renin-angiotensin system in immunosuppression of tumor microenvironment. Cancer Science. PMID 29034589 DOI: 10.1111/cas.13423  0.457
2017 Kinoshita T, Kudo-Saito C, Muramatsu R, Fujita T, Saito M, Nagumo H, Sakurai T, Noji S, Takahata E, Yaguchi T, Tsukamoto N, Hayashi Y, Kaseda K, Kamiyama I, Ohtsuka T, ... ... Kawakami Y, et al. Determination of poor prognostic immune features of tumour microenvironment in non-smoking patients with lung adenocarcinoma. European Journal of Cancer (Oxford, England : 1990). 86: 15-27. PMID 28950145 DOI: 10.1016/j.ejca.2017.08.026  0.385
2017 Matsushita M, Ozawa K, Suzuki T, Nakamura M, Nakano N, Kanchi S, Ichikawa D, Matsuki E, Sakurai M, Karigane D, Kasahara H, Tsukamoto N, Shimizu T, Mori T, Nakajima H, ... ... Kawakami Y, et al. CXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients. Blood Cancer Journal. 7: e601. PMID 28862699 DOI: 10.1038/bcj.2017.84  0.382
2017 Jinushi M, Morita T, Xu Z, Kinoshita I, Dosaka-Akita H, Yagita H, Kawakami Y. Autophagy-dependent regulation of tumor metastasis by myeloid cells. Plos One. 12: e0179357. PMID 28686632 DOI: 10.1371/journal.pone.0179357  0.406
2017 Kato D, Yaguchi T, Iwata T, Morii K, Nakagawa T, Nishimura R, Kawakami Y. Prospects for personalized combination immunotherapy for solid tumors based on adoptive cell therapies and immune checkpoint blockade therapies. Nihon Rinsho Men'Eki Gakkai Kaishi = Japanese Journal of Clinical Immunology. 40: 68-77. PMID 28539557 DOI: 10.2177/jsci.40.68  0.452
2017 Miyauchi T, Yaguchi T, Kawakami Y. Inter-patient and Intra-tumor Heterogeneity in the Sensitivity to Tumor-targeted Immunity in Colorectal Cancer. Nihon Rinsho Men'Eki Gakkai Kaishi = Japanese Journal of Clinical Immunology. 40: 54-59. PMID 28539555 DOI: 10.2177/jsci.40.54  0.415
2017 Fukuda K, Funakoshi T, Sakurai T, Nakamura Y, Mori M, Tanese K, Tanikawa A, Taguchi J, Fujita T, Okamoto M, Amagai M, Kawakami Y. Peptide-pulsed dendritic cell vaccine in combination with carboplatin and paclitaxel chemotherapy for stage IV melanoma. Melanoma Research. PMID 28263240 DOI: 10.1097/CMR.0000000000000342  0.337
2017 Miyazaki J, Ito K, Fujita T, Matsuzaki Y, Asano T, Hayakawa M, Asano T, Kawakami Y. Progression of Human Renal Cell Carcinoma via Inhibition of RhoA-ROCK Axis by PARG1. Translational Oncology. 10: 142-152. PMID 28131798 DOI: 10.1016/j.tranon.2016.12.004  0.384
2017 Mori M, Funakoshi T, Kameyama K, Kawakami Y, Sato E, Nakayama E, Amagai M, Tanese K. Lack of XAGE-1b and NY-ESO-1 in metastatic lymph nodes may predict the potential survival of stage III melanoma patients. The Journal of Dermatology. PMID 28105694 DOI: 10.1111/1346-8138.13730  0.4
2017 Saito K, Ohta S, Kawakami Y, Yoshida K, Toda M. Functional analysis of KIF20A, a potential immunotherapeutic target for glioma. Journal of Neuro-Oncology. PMID 28070829 DOI: 10.1007/s11060-016-2360-1  0.581
2017 Kinoshita T, Fujita T, Hayashi Y, Ohtsuka T, Mitsudomi T, Asamura H, Yasufuku K, Kawakami Y. MA 05.04 Distinct Immunosuppressive Microenvironment Determines Poor Prognosis of Nonsmokers with Adenocarcinoma of Non-Small Cell Lung Cancer Journal of Thoracic Oncology. 12: S1816. DOI: 10.1016/j.jtho.2017.09.481  0.307
2017 Nakamura K, Yaguchi T, Murata M, Ota Y, Kiniwa Y, Okuyama R, Kawakami Y. 772 A BRAF inhibitor and a Toll-like receptor 7 agonist synergistically enhanced anti-tumor immune responses Journal of Investigative Dermatology. 137: S133. DOI: 10.1016/j.jid.2017.02.797  0.323
2016 Ohta S, Yaguchi T, Okuno H, Chneiweiss H, Kawakami Y, Okano H. CHD7 promotes proliferation of neural stem cells mediated by MIF. Molecular Brain. 9: 96. PMID 27955690 DOI: 10.1186/S13041-016-0275-6  0.377
2016 Xu Z, Shioda S, Jinushi M, Kawakami Y, Ohtaki H, Wang S, Zhao X, Liu Y, Zhou D, Guo Y. Role of the autonomic nervous system in the tumor micro-environment and its therapeutic potential. Current Pharmaceutical Design. PMID 27784236 DOI: 10.2174/1381612822666161025152942  0.372
2016 Kinoshita T, Muramatsu R, Fujita T, Nagumo H, Sakurai T, Noji S, Takahata E, Yaguchi T, Tsukamoto N, Kudo-Saito C, Hayashi Y, Kamiyama I, Ohtsuka T, Asamura H, Kawakami Y. Prognostic value of tumor-infiltrating lymphocytes differs depending on histological type and smoking habit in completely resected non-small cell lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 27502728 DOI: 10.1093/annonc/mdw319  0.369
2016 Yaguchi T, Kawakami Y. Cancer-induced heterogeneous immunosuppressive tumor microenvironments and their personalized modulation. International Immunology. PMID 27401477 DOI: 10.1093/intimm/dxw030  0.394
2016 Kudo-Saito C, Fuwa T, Kawakami Y. Targeting ALCAM in the cryo-treated tumour microenvironment successfully induces systemic anti-tumour immunity. European Journal of Cancer (Oxford, England : 1990). 62: 54-61. PMID 27208904 DOI: 10.1016/j.ejca.2016.04.013  0.413
2016 Fukaya R, Ohta S, Yaguchi T, Matsuzaki Y, Sugihara E, Okano H, Saya H, Kawakami Y, Kawase T, Yoshida K, Toda M. MIF maintains the tumorigenic capacity of brain tumor-initiating cells by directly inhibiting p53. Cancer Research. PMID 26980763 DOI: 10.1158/0008-5472.Can-15-1011  0.546
2016 Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Yaguchi T, Sato Y, Mukai S, Yaguchi S, Inaba T, Okamoto S, Kawakami Y, Tsubota K, Matsuzaki Y, Shimmura S. MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model. Elife. 5. PMID 26809474 DOI: 10.7554/Elife.09394  0.369
2016 Matsushita M, Otsuka Y, Tsutsumida N, Tanaka C, Uchiumi A, Ozawa K, Suzuki T, Ichikawa D, Aburatani H, Okamoto S, Kawakami Y, Hattori Y. Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies. Plos One. 11: e0146371. PMID 26784514 DOI: 10.1371/journal.pone.0146371  0.451
2016 Inozume T, Yaguchi T, Furuta J, Harada K, Kawakami Y, Shimada S. Melanoma Cells Control Antimelanoma CTL Responses via Interaction between TIGIT and CD155 in the Effector Phase. The Journal of Investigative Dermatology. 136: 255-63. PMID 26763445 DOI: 10.1038/JID.2015.404  0.395
2016 Galon J, Mlecnik B, Marliot F, Ou F, Bifulco CB, Lugli A, Zlobec I, Rau TT, Hartmann A, Masucci GV, Zavadova E, Ohashi P, Roehrl MHA, Kawakami Y, Torigoe T, et al. Validation of the Immunoscore (IM) as a prognostic marker in stage I/II/III colon cancer: Results of a worldwide consortium-based analysis of 1,336 patients. Journal of Clinical Oncology. 34: 3500-3500. DOI: 10.1200/Jco.2016.34.15_Suppl.3500  0.318
2016 Althammer S, Steele K, Rebelatto M, Tan TH, Wiestler T, Schmidt G, Higgs B, Li X, Shi L, Jin X, Antal J, Gupta A, Ranade K, Binning G, Bellmunt J, ... ... Kawakami Y, et al. 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts Journal For Immunotherapy of Cancer. 4. DOI: 10.1186/S40425-016-0191-4  0.319
2016 Inozume T, Yaguchi T, Furuta J, Harada K, Kawakami Y, Shimada S. Co-blockade of TIGIT and PD-1 signals in tumor-infiltrating cytotoxic T lymphocytes is an effective anti-melanoma therapy Journal of Dermatological Science. 84: e155. DOI: 10.1016/j.jdermsci.2016.08.461  0.332
2016 Inozume T, Yaguchi T, Furuta J, Itoh M, Kawakami Y, Shimada S. Blockade for CD155-TIGIT interaction elicits anti-melanoma T cell responses in vitro and in vivo Journal of Dermatological Science. 84: e61. DOI: 10.1016/j.jdermsci.2016.08.190  0.344
2015 Kawakami Y. [Cancer immunotherapy by immuno-checkpoint blockade]. [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology. 56: 2186-94. PMID 26458459 DOI: 10.11406/rinketsu.56.2186  0.398
2015 Yamaguchi SI, Ueki A, Sugihara E, Onishi N, Yaguchi T, Kawakami Y, Horiuchi K, Morioka H, Matsumoto M, Nakamura M, Muto A, Toyama Y, Saya H, Shimizu T. Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells. Cancer Science. 106: 875-82. PMID 25940371 DOI: 10.1111/cas.12686  0.41
2015 Namiki T, Yaguchi T, Nakamura K, Valencia JC, Coelho SG, Yin L, Kawaguchi M, Vieira WD, Kaneko Y, Tanemura A, Katayama I, Yokozeki H, Kawakami Y, Hearing VJ. NUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation. Cancer Research. 75: 2708-15. PMID 25832654 DOI: 10.1158/0008-5472.Can-13-3209  0.356
2015 Katano I, Takahashi T, Ito R, Kamisako T, Mizusawa T, Ka Y, Ogura T, Suemizu H, Kawakami Y, Ito M. Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse. Journal of Immunology (Baltimore, Md. : 1950). 194: 3513-25. PMID 25712215 DOI: 10.4049/jimmunol.1401323  0.347
2015 Mayanagi S, Kitago M, Sakurai T, Matsuda T, Fujita T, Higuchi H, Taguchi J, Takeuchi H, Itano O, Aiura K, Hamamoto Y, Takaishi H, Okamoto M, Sunamura M, Kawakami Y, et al. Phase I pilot study of Wilms tumor gene 1 peptide-pulsed dendritic cell vaccination combined with gemcitabine in pancreatic cancer. Cancer Science. 106: 397-406. PMID 25614082 DOI: 10.1111/cas.12621  0.438
2015 Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Yaguchi T, Sato Y, Mukai S, Yaguchi S, Inaba T, Okamoto S, Kawakami Y, Tsubota K, Matsuzaki Y, Shimmura S. Author response: MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model Elife. DOI: 10.7554/Elife.09394.034  0.332
2015 Yaguchi T, Morii K, Serada S, Naka T, Kawakami Y. Development of anti-GPC-1 (glypican-1)-CAR-T cells for adoptive T cell immunotherapies for squamous cell carcinoma Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P125  0.459
2014 Fujita Y, Okamoto M, Goda H, Tano T, Nakashiro K, Sugita A, Fujita T, Koido S, Homma S, Kawakami Y, Hamakawa H. Prognostic significance of interleukin-8 and CD163-positive cell-infiltration in tumor tissues in patients with oral squamous cell carcinoma. Plos One. 9: e110378. PMID 25461761 DOI: 10.1371/journal.pone.0110378  0.35
2014 Saito K, Iizuka Y, Ohta S, Takahashi S, Nakamura K, Saya H, Yoshida K, Kawakami Y, Toda M. Functional analysis of a novel glioma antigen, EFTUD1. Neuro-Oncology. 16: 1618-29. PMID 25015090 DOI: 10.1093/neuonc/nou132  0.638
2014 Hazama S, Nakamura Y, Tanaka H, Hirakawa K, Tahara K, Shimizu R, Ozasa H, Etoh R, Sugiura F, Okuno K, Furuya T, Nishimura T, Sakata K, Yoshimatsu K, Takenouchi H, ... ... Kawakami Y, et al. A phase ΙI study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study). Journal of Translational Medicine. 12: 108. PMID 24884643 DOI: 10.1186/1479-5876-12-108  0.328
2014 Nishio H, Yaguchi T, Sugiyama J, Sumimoto H, Umezawa K, Iwata T, Susumu N, Fujii T, Kawamura N, Kobayashi A, Park J, Aoki D, Kawakami Y. Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor. British Journal of Cancer. 110: 2965-74. PMID 24867687 DOI: 10.1038/bjc.2014.251  0.372
2014 Kawamura N, Udagawa M, Fujita T, Sakurai T, Yaguchi T, Kawakami Y. Intratumoral injection of BCG-CWS-pretreated dendritic cells following tumor cryoablation. Methods in Molecular Biology (Clifton, N.J.). 1139: 145-53. PMID 24619677 DOI: 10.1007/978-1-4939-0345-0_13  0.424
2014 Kudo-Saito C, Yura M, Yamamoto R, Kawakami Y. Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H. Cancer Research. 74: 1361-70. PMID 24590808 DOI: 10.1158/0008-5472.CAN-13-1349  0.447
2014 Nakamura S, Yaguchi T, Kawamura N, Kobayashi A, Sakurai T, Higuchi H, Takaishi H, Hibi T, Kawakami Y. TGF-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression. Journal of Immunotherapy (Hagerstown, Md. : 1997). 37: 63-72. PMID 24509168 DOI: 10.1097/CJI.0000000000000011  0.412
2014 Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, ... ... Kawakami Y, et al. Towards the introduction of the 'Immunoscore' in the classification of malignant tumours. The Journal of Pathology. 232: 199-209. PMID 24122236 DOI: 10.1002/path.4287  0.356
2014 Hayakawa T, Sugiyama J, Yaguchi T, Imaizumi A, Kawakami Y. Enhanced anti-tumor effects of the PD-1/PD-L1 blockade by combining a highly absorptive form of NF-kB/STAT3 inhibitor curcumin Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-S3-P210  0.397
2014 Matsushita M, Nakamura M, Ichikawa D, Tsukamoto N, Kawakami Y, Hattori Y. Identification of Novel Cancer-Testis Antigen Expressed in Leukemic Stem Cells of Chronic Myelogenous Leukemia Experimental Hematology. 42: S68. DOI: 10.1016/j.exphem.2014.07.270  0.384
2013 Ohta S, Misawa A, Lefebvre V, Okano H, Kawakami Y, Toda M. Sox6 up-regulation by macrophage migration inhibitory factor promotes survival and maintenance of mouse neural stem/progenitor cells. Plos One. 8: e74315. PMID 24066135 DOI: 10.1371/Journal.Pone.0074315  0.502
2013 Kudo-Saito C, Fuwa T, Murakami K, Kawakami Y. Targeting FSTL1 prevents tumor bone metastasis and consequent immune dysfunction. Cancer Research. 73: 6185-93. PMID 23966294 DOI: 10.1158/0008-5472.CAN-13-1364  0.363
2013 Tano T, Okamoto M, Kan S, Bando T, Goda H, Nakashiro K, Shimodaira S, Koido S, Homma S, Fujita T, Sato M, Yamashita N, Hamakawa H, Kawakami Y. Immunochemoradiotherapy for patients with oral squamous cell carcinoma: augmentation of OK-432-induced helper T cell 1 response by 5-FU and X-ray irradiation. Neoplasia (New York, N.Y.). 15: 805-14. PMID 23814492 DOI: 10.1593/neo.13488  0.356
2013 Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Iwata-Kajihara T, Nakamura S, Tsujikawa T, Park JH, Popivanova BK, Miyazaki J, Kawamura N. Improvement of cancer immunotherapy by combining molecular targeted therapy. Frontiers in Oncology. 3: 136. PMID 23755373 DOI: 10.3389/fonc.2013.00136  0.41
2013 Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Park JH, Kamijuku H, Tsujikawa T, Kawamura N. Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy. Annals of the New York Academy of Sciences. 1284: 80-6. PMID 23651199 DOI: 10.1111/nyas.12094  0.443
2013 Ohta S, Imaizumi Y, Akamatsu W, Okano H, Kawakami Y. Generation of human melanocytes from induced pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 989: 193-215. PMID 23483397 DOI: 10.1007/978-1-62703-330-5_16  0.329
2013 Tano T, Okamoto M, Kan S, Nakashiro K, Shimodaira S, Koido S, Homma S, Sato M, Fujita T, Kawakami Y, Hamakawa H. Prognostic impact of expression of Bcl-2 and Bax genes in circulating immune cells derived from patients with head and neck carcinoma. Neoplasia (New York, N.Y.). 15: 305-14. PMID 23479508 DOI: 10.1593/neo.121528  0.379
2013 Tsujikawa T, Yaguchi T, Ohmura G, Ohta S, Kobayashi A, Kawamura N, Fujita T, Nakano H, Shimada T, Takahashi T, Nakao R, Yanagisawa A, Hisa Y, Kawakami Y. Autocrine and paracrine loops between cancer cells and macrophages promote lymph node metastasis via CCR4/CCL22 in head and neck squamous cell carcinoma. International Journal of Cancer. Journal International Du Cancer. 132: 2755-66. PMID 23180648 DOI: 10.1002/ijc.27966  0.364
2013 Kudo-Saito C, Shirako H, Ohike M, Tsukamoto N, Kawakami Y. CCL2 is critical for immunosuppression to promote cancer metastasis. Clinical & Experimental Metastasis. 30: 393-405. PMID 23143679 DOI: 10.1007/s10585-012-9545-6  0.456
2013 Akagi H, Higuchi H, Sumimoto H, Igarashi T, Kabashima A, Mizuguchi H, Izumiya M, Sakai G, Adachi M, Funakoshi S, Nakamura S, Hamamoto Y, Kanai T, Takaishi H, Kawakami Y, et al. Suppression of myeloid cell leukemia-1 (Mcl-1) enhances chemotherapy-associated apoptosis in gastric cancer cells. Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 16: 100-10. PMID 22527182 DOI: 10.1007/s10120-012-0153-6  0.356
2013 Yaguchi T, Kobayashi A, Katano I, Ka Y, Ito M, Kawakami Y. MHC class I/II deficient NOG mice are useful for analysis of human T/B cell responses for human tumor immunology research Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P39  0.433
2013 Nishio H, Sugiyama J, Yaguchi T, Aoki D, Kawakami Y. Immunosuppression through HNF-1β signaling in human ovarian clear cell cancer Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P168  0.341
2013 Kudo-Saito C, Kawakami Y. Abstract 283: Cancer MET at the metastatic lesion preserves the malignant features acquired via EMT. Cancer Research. 73: 283-283. DOI: 10.1158/1538-7445.Am2013-283  0.426
2012 Galon J, Pagès F, Marincola FM, Angell HK, Thurin M, Lugli A, Zlobec I, Berger A, Bifulco C, Botti G, Tatangelo F, Britten CM, Kreiter S, Chouchane L, Delrio P, ... ... Kawakami Y, et al. Cancer classification using the Immunoscore: a worldwide task force. Journal of Translational Medicine. 10: 205. PMID 23034130 DOI: 10.1186/1479-5876-10-205  0.383
2012 Yaguchi T, Goto Y, Kido K, Mochimaru H, Sakurai T, Tsukamoto N, Kudo-Saito C, Fujita T, Sumimoto H, Kawakami Y. Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 2110-7. PMID 22815287 DOI: 10.4049/jimmunol.1102282  0.39
2012 Mishima K, Inoue H, Nishiyama T, Mabuchi Y, Amano Y, Ide F, Matsui M, Yamada H, Yamamoto G, Tanaka J, Yasuhara R, Sakurai T, Lee MC, Chiba K, Sumimoto H, ... Kawakami Y, et al. Transplantation of side population cells restores the function of damaged exocrine glands through clusterin. Stem Cells (Dayton, Ohio). 30: 1925-37. PMID 22782911 DOI: 10.1002/stem.1173  0.341
2012 Okabayashi K, Fujita T, Miyazaki J, Okada T, Iwata T, Hirao N, Noji S, Tsukamoto N, Goshima N, Hasegawa H, Takeuchi H, Ueda M, Kitagawa Y, Kawakami Y. Cancer-testis antigen BORIS is a novel prognostic marker for patients with esophageal cancer. Cancer Science. 103: 1617-24. PMID 22676270 DOI: 10.1111/j.1349-7006.2012.02355.x  0.431
2012 Ohta S, Misawa A, Fukaya R, Inoue S, Kanemura Y, Okano H, Kawakami Y, Toda M. Macrophage migration inhibitory factor (MIF) promotes cell survival and proliferation of neural stem/progenitor cells. Journal of Cell Science. 125: 3210-20. PMID 22454509 DOI: 10.1242/Dev.088658  0.531
2012 Tano T, Okamoto M, Kan S, Nakashiro K, Shimodaira S, Yamashita N, Kawakami Y, Hamakawa H. Growth inhibition and apoptosis by an active component of OK-432, a streptococcal agent, via Toll-like receptor 4 in human head and neck cancer cell lines. Oral Oncology. 48: 678-85. PMID 22387210 DOI: 10.1016/j.oraloncology.2012.02.005  0.338
2012 Shimizu T, Ishikawa T, Iwai S, Ueki A, Sugihara E, Onishi N, Kuninaka S, Miyamoto T, Toyama Y, Ijiri H, Mori H, Matsuzaki Y, Yaguchi T, Nishio H, Kawakami Y, et al. Fibroblast growth factor-2 is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma. Molecular Cancer Research : McR. 10: 454-68. PMID 22228819 DOI: 10.1158/1541-7786.MCR-11-0347  0.366
2012 Takahashi S, Fusaki N, Ohta S, Iwahori Y, Iizuka Y, Inagawa K, Kawakami Y, Yoshida K, Toda M. Downregulation of KIF23 suppresses glioma proliferation. Journal of Neuro-Oncology. 106: 519-29. PMID 21904957 DOI: 10.1007/s11060-011-0706-2  0.653
2012 Tatematsu Y, Ogawa Y, Shimmura S, Dogru M, Yaguchi S, Nagai T, Yamazaki K, Kameyama K, Okamoto S, Kawakami Y, Tsubota K. Mucosal microvilli in dry eye patients with chronic GVHD. Bone Marrow Transplantation. 47: 416-25. PMID 21572465 DOI: 10.1038/bmt.2011.89  0.302
2012 Kudo-Saito C, Kawakami Y. Abstract 5403: Snail+ bone-metastatic cancer cells impair CTL induction via induction of immunoregulatory MSCs Cancer Research. 72: 5403-5403. DOI: 10.1158/1538-7445.Am2012-5403  0.456
2012 Matsushita M, Suzuki T, Tsutsumida N, Iijima S, Tsukamoto N, Kawakami Y, Matsuki E, Okamoto S, Hattori Y. Abstract 2682: New diagnostic and therapeutic target KU-MEL9 for chronic myeloid leukemia (CML) Cancer Research. 72: 2682-2682. DOI: 10.1158/1538-7445.Am2012-2682  0.398
2012 Yaguchi S, Shimmura S, Inaba T, Matsuzaki Y, Okamoto S, Kawakami Y, Ogawa Y, Morikawa S, Okano H, Mabuchi Y, Suzuki S, Tsubota K, Yaguchi T. Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation Nature Precedings. 7: 1-1. DOI: 10.1038/Npre.2012.6843.1  0.356
2011 Fox BA, Schendel DJ, Butterfield LH, Aamdal S, Allison JP, Ascierto PA, Atkins MB, Bartunkova J, Bergmann L, Berinstein N, Bonorino CC, Borden E, Bramson JL, Britten CM, Cao X, ... ... Kawakami Y, et al. Defining the critical hurdles in cancer immunotherapy. Journal of Translational Medicine. 9: 214. PMID 22168571 DOI: 10.1186/1479-5876-9-214  0.313
2011 Iwata-Kajihara T, Sumimoto H, Kawamura N, Ueda R, Takahashi T, Mizuguchi H, Miyagishi M, Takeda K, Kawakami Y. Enhanced cancer immunotherapy using STAT3-depleted dendritic cells with high Th1-inducing ability and resistance to cancer cell-derived inhibitory factors. Journal of Immunology (Baltimore, Md. : 1950). 187: 27-36. PMID 21632716 DOI: 10.4049/jimmunol.1002067  0.424
2011 Tabuse M, Ohta S, Ohashi Y, Fukaya R, Misawa A, Yoshida K, Kawase T, Saya H, Thirant C, Chneiweiss H, Matsuzaki Y, Okano H, Kawakami Y, Toda M. Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells. Molecular Cancer. 10: 60. PMID 21600039 DOI: 10.1186/1476-4598-10-60  0.66
2011 Butterfield LH, Palucka AK, Britten CM, Dhodapkar MV, HÃ¥kansson L, Janetzki S, Kawakami Y, Kleen TO, Lee PP, Maccalli C, Maecker HT, Maino VC, Maio M, Malyguine A, Masucci G, et al. Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3064-76. PMID 21558394 DOI: 10.1158/1078-0432.Ccr-10-2234  0.326
2011 Namiki T, Tanemura A, Valencia JC, Coelho SG, Passeron T, Kawaguchi M, Vieira WD, Ishikawa M, Nishijima W, Izumo T, Kaneko Y, Katayama I, Yamaguchi Y, Yin L, Polley EC, ... ... Kawakami Y, et al. AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma. Proceedings of the National Academy of Sciences of the United States of America. 108: 6597-602. PMID 21460252 DOI: 10.1073/Pnas.1007694108  0.394
2011 Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Ueda R, Iwata-Kajihara T, Nishio H, Kawamura N, Kawakami Y. The mechanisms of cancer immunoescape and development of overcoming strategies. International Journal of Hematology. 93: 294-300. PMID 21374075 DOI: 10.1007/s12185-011-0799-6  0.383
2011 Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohyama M, Amagai M, Matsuzaki Y, Yamanaka S, Okano H, Kawakami Y. Generation of human melanocytes from induced pluripotent stem cells. Plos One. 6: e16182. PMID 21249204 DOI: 10.1371/Journal.Pone.0016182  0.37
2011 Ohkusu-Tsukada K, Ohta S, Kawakami Y, Toda M. Adjuvant effects of formalin-inactivated HSV through activation of dendritic cells and inactivation of myeloid-derived suppressor cells in cancer immunotherapy. International Journal of Cancer. Journal International Du Cancer. 128: 119-31. PMID 20232389 DOI: 10.1002/ijc.25319  0.529
2011 Ohta S, Misawa A, Okuno H, Fukuda K, Akamatsu W, Kawakami Y, Okano H. Generation of neural crest progenitor cells from human induced pluripotent stem cells by a simple method Neuroscience Research. 71: e127. DOI: 10.1016/J.Neures.2011.07.541  0.309
2010 Fujimoto T, Nishimura T, Goto-Kazeto R, Kawakami Y, Yamaha E, Arai K. Sexual dimorphism of gonadal structure and gene expression in germ cell-deficient loach, a teleost fish. Proceedings of the National Academy of Sciences of the United States of America. 107: 17211-6. PMID 20855617 DOI: 10.1073/pnas.1007032107  0.307
2010 Baba T, Sato-Matsushita M, Kanamoto A, Itoh A, Oyaizu N, Inoue Y, Kawakami Y, Tahara H. Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A*2402. Journal of Translational Medicine. 8: 84. PMID 20843377 DOI: 10.1186/1479-5876-8-84  0.388
2010 Kawakami Y. [Cancer treatment by comprehensive regulation of anti-tumor immune network]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 68: 1094-9. PMID 20535961  0.343
2010 Ohkusu-Tsukada K, Toda M, Udono H, Kawakami Y, Takahashi K. Targeted inhibition of IL-10-secreting CD25- Treg via p38 MAPK suppression in cancer immunotherapy. European Journal of Immunology. 40: 1011-21. PMID 20127675 DOI: 10.1002/eji.200939513  0.498
2010 Fukaya R, Ohta S, Yamaguchi M, Fujii H, Kawakami Y, Kawase T, Toda M. Isolation of cancer stem-like cells from a side population of a human glioblastoma cell line, SK-MG-1. Cancer Letters. 291: 150-7. PMID 19913993 DOI: 10.1016/j.canlet.2009.10.010  0.545
2010 Ueda R, Ohkusu-Tsukada K, Fusaki N, Soeda A, Kawase T, Kawakami Y, Toda M. Identification of HLA-A2- and A24-restricted T-cell epitopes derived from SOX6 expressed in glioma stem cells for immunotherapy. International Journal of Cancer. Journal International Du Cancer. 126: 919-29. PMID 19728337 DOI: 10.1002/ijc.24851  0.569
2010 Goto Y, Koyanagi K, Narita N, Kawakami Y, Takata M, Uchiyama A, Nguyen L, Nguyen T, Ye X, Morton DL, Hoon DS. Aberrant fatty acid-binding protein-7 gene expression in cutaneous malignant melanoma. The Journal of Investigative Dermatology. 130: 221-9. PMID 19587692 DOI: 10.1038/jid.2009.195  0.375
2010 Kudo-Saito C, Kawakami Y. Abstract 5326: CCL2 is critical for immunoresistance in association with cancer EMT Cancer Research. 70: 5326-5326. DOI: 10.1158/1538-7445.Am10-5326  0.449
2010 Satomi R, Naoki K, Yaguchi T, Yasuda H, Nakayama S, Yoda S, Terai H, Ikemura S, Sato T, Soejima K, Ishizaka A, Kawakami Y. Abstract 5302: Overcoming cancer immune evasion in lung carcinoma using EGFR-TKI (Gefitinib) Cancer Research. 70: 5302-5302. DOI: 10.1158/1538-7445.Am10-5302  0.351
2010 Daisuke M, Nishikawa H, Kato T, Wang L, Maeda Y, Harada N, Noguchi T, Kawakami Y, Shiku H. Abstract 4751: Peptide vaccine induces apoptosis of antigen-specific CD8+T cells Cancer Research. 70: 4751-4751. DOI: 10.1158/1538-7445.Am10-4751  0.436
2010 Smyth MJ, Ngiow S, Sparwasser T, Teng MWL, Kawakami Y, Sumimoto H, Iwata-Kajihara T, Yaguchi T, Kawamura N, Kudo-Saito C, Tsukamoto N, Qazi MR, Abedi M, Nelson B, DePierre J, et al. Tumor immunity and immunosurveillance, session 1 (WS-093a) Chairpersons: Kazuyoshi Takeda, Bruce Robinson International Immunology. 22. DOI: 10.1093/Intimm/Dxq348  0.324
2010 Ohta S, Kawakami Y, Okano H, Toda M. Functional analysis of macrophage migration inhibitory factor (MIF) in the mouse neural stem/progenitor cells Neuroscience Research. 68: e245-e246. DOI: 10.1016/J.Neures.2010.07.1088  0.463
2010 Ohta S, Kawakami Y, Okano H, Toda M. P45. Functional analysis of macrophage migration inhibitory factor (MIF) in the mouse neural stem/progenitor cells Differentiation. 80: S32. DOI: 10.1016/J.Diff.2010.09.051  0.515
2009 Tsukamoto N, Okada S, Onami Y, Sasaki Y, Umezawa K, Kawakami Y. Impairment of plasmacytoid dendritic cells for IFN production by the ligand for immunoglobulin-like transcript 7 expressed on human cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5733-43. PMID 19723650 DOI: 10.1158/1078-0432.CCR-09-0171  0.418
2009 Kido K, Sumimoto H, Asada S, Okada SM, Yaguchi T, Kawamura N, Miyagishi M, Saida T, Kawakami Y. Simultaneous suppression of MITF and BRAF V600E enhanced inhibition of melanoma cell proliferation. Cancer Science. 100: 1863-9. PMID 19659611 DOI: 10.1111/j.1349-7006.2009.01266.x  0.39
2009 Sato S, Hoshino K, Satoh T, Fujita T, Kawakami Y, Fujita T, Kuwana M. RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease. Arthritis and Rheumatism. 60: 2193-200. PMID 19565506 DOI: 10.1002/art.24621  0.364
2009 Tahara H, Sato M, Thurin M, Wang E, Butterfield LH, Disis ML, Fox BA, Lee PP, Khleif SN, Wigginton JM, Ambs S, Akutsu Y, Chaussabel D, Doki Y, Eremin O, ... ... Kawakami Y, et al. Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology. Journal of Translational Medicine. 7: 45. PMID 19534815 DOI: 10.1186/1479-5876-7-45  0.362
2009 Hayashi K, Ohta S, Kawakami Y, Toda M. Activation of dendritic-like cells and neural stem/progenitor cells in injured spinal cord by GM-CSF. Neuroscience Research. 64: 96-103. PMID 19428687 DOI: 10.1016/j.neures.2009.01.018  0.459
2009 Kudo-Saito C, Shirako H, Takeuchi T, Kawakami Y. Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells. Cancer Cell. 15: 195-206. PMID 19249678 DOI: 10.1016/j.ccr.2009.01.023  0.449
2009 Ohta S, Kawakami Y, Okano H, Kawase T, Toda M. Macrophage migration inhibitory factor (MIF) promotes proliferation and cell survival of neural stem/progenitor cells Neuroscience Research. 65: S91. DOI: 10.1016/J.Neures.2009.09.375  0.485
2008 Li Z, Oka Y, Tsuboi A, Fujiki F, Harada Y, Nakajima H, Masuda T, Fukuda Y, Kawakatsu M, Morimoto S, Katagiri T, Tatsumi N, Hosen N, Shirakata T, Nishida S, ... Kawakami Y, et al. Identification of a WT1 protein-derived peptide, WT1, as a HLA-A 0206-restricted, WT1-specific CTL epitope. Microbiology and Immunology. 52: 551-8. PMID 19090835 DOI: 10.1111/j.1348-0421.2008.00069.x  0.374
2008 Matsumoto K, Kubo H, Murata H, Uhara H, Takata M, Shibata S, Yasue S, Sakakibara A, Tomita Y, Kageshita T, Kawakami Y, Mizuno M, Yoshida J, Saida T. A pilot study of human interferon beta gene therapy for patients with advanced melanoma by in vivo transduction using cationic liposomes. Japanese Journal of Clinical Oncology. 38: 849-56. PMID 18945721 DOI: 10.1093/Jjco/Hyn114  0.362
2008 Seta N, Tajima M, Kobayashi S, Kawakami Y, Hashimoto H, Kuwana M. Autoreactive T-cell responses to myeloperoxidase in patients with antineutrophil cytoplasmic antibody-associated vasculitis and in healthy individuals. Modern Rheumatology / the Japan Rheumatism Association. 18: 593-600. PMID 18806928 DOI: 10.1007/s10165-008-0109-1  0.389
2008 Takahashi H, Amagai M, Nishikawa T, Fujii Y, Kawakami Y, Kuwana M. Novel system evaluating in vivo pathogenicity of desmoglein 3-reactive T cell clones using murine pemphigus vulgaris. Journal of Immunology (Baltimore, Md. : 1950). 181: 1526-35. PMID 18606708 DOI: 10.4049/Jimmunol.181.2.1526  0.373
2008 Yaguchi M, Ohta S, Toyama Y, Kawakami Y, Toda M. Functional recovery after spinal cord injury in mice through activation of microglia and dendritic cells after IL-12 administration. Journal of Neuroscience Research. 86: 1972-80. PMID 18438913 DOI: 10.1002/jnr.21658  0.451
2008 Mochimaru H, Usui T, Yaguchi T, Nagahama Y, Hasegawa G, Usui Y, Shimmura S, Tsubota K, Amano S, Kawakami Y, Ishida S. Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2. Investigative Ophthalmology & Visual Science. 49: 2172-7. PMID 18263815 DOI: 10.1167/iovs.07-1396  0.393
2008 Ueda R, Kinoshita E, Ito R, Kawase T, Kawakami Y, Toda M. Induction of protective and therapeutic antitumor immunity by a DNA vaccine with a glioma antigen, SOX6. International Journal of Cancer. Journal International Du Cancer. 122: 2274-9. PMID 18224680 DOI: 10.1002/ijc.23366  0.536
2008 Ohta S, Ueda Y, Yaguchi M, Matsuzaki Y, Nakamura M, Toyama Y, Tanioka Y, Tamaoki N, Nomura T, Okano H, Kawakami Y, Toda M. Isolation and characterization of dendritic cells from common marmosets for preclinical cell therapy studies. Immunology. 123: 566-74. PMID 18005037 DOI: 10.1111/J.1365-2567.2007.02727.X  0.545
2008 Kawakami Y, Fujita T, Kudo C, Sakurai T, Udagawa M, Yaguchi T, Hasegawa G, Hayashi E, Ueda Y, Iwata T, Wang Q, Okada S, Tsukamoto N, Matsuzaki Y, Sumimoto H. Dendritic cell based personalized immunotherapy based on cancer antigen research. Frontiers in Bioscience : a Journal and Virtual Library. 13: 1952-8. PMID 17981682 DOI: 10.2741/2814  0.458
2008 Ogawa Y, Shimmura S, Kuwana M, Yamazaki K, Kawakami Y, Tsubota K. Inflammation and pathogenic fibrosis in human ocular chronic graft versus host disease Inflammation and Regeneration. 28: 529-536. DOI: 10.2492/INFLAMMREGEN.28.529  0.338
2008 Ito K, Noji S, Asano T, Ikegami S, Yoshii H, Horiguchi A, Kimura F, Sumitomo M, Fujita T, Asano T, Murai M, Kawakami Y, Hayakawa M. Increased Expression Of Nucleophosmin Is Associated With Worse Pathological Features And Predicts Intravesical Recurrence In Patients With Bladder Cancer The Journal of Urology. 179: 318-318. DOI: 10.1016/S0022-5347(08)60931-3  0.301
2007 Hattori Y, Ohta S, Hamada K, Yamada-Okabe H, Kanemura Y, Matsuzaki Y, Okano H, Kawakami Y, Toda M. Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1. Biochemical and Biophysical Research Communications. 364: 737-42. PMID 17981261 DOI: 10.1016/J.Bbrc.2007.10.041  0.484
2007 Hayashi E, Matsuzaki Y, Hasegawa G, Yaguchi T, Kurihara S, Fujita T, Kageshita T, Sano M, Kawakami Y. Identification of a novel cancer-testis antigen CRT2 frequently expressed in various cancers using representational differential analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6267-74. PMID 17975137 DOI: 10.1158/1078-0432.CCR-07-1374  0.438
2007 Kawakami Y. [The possibility and limitations of cell therapy. 2) The current status and overview of tumor-immune cell therapy--T cell-dendritic cell therapy]. Nihon Naika Gakkai Zasshi. the Journal of the Japanese Society of Internal Medicine. 96: 1923-8. PMID 17929434 DOI: 10.2169/Naika.96.1923  0.374
2007 Mochimaru H, Nagai N, Hasegawa G, Kudo-Saito C, Yaguchi T, Usui Y, Kurihara T, Koto T, Satofuka S, Shinoda H, Ozawa Y, Tsubota K, Kawakami Y, Ishida S. Suppression of choroidal neovascularization by dendritic cell vaccination targeting VEGFR2. Investigative Ophthalmology & Visual Science. 48: 4795-801. PMID 17898306 DOI: 10.1167/iovs.07-0425  0.382
2007 Inozume T, Mitsui H, Okamoto T, Matsuzaki Y, Kawakami Y, Shibagaki N, Shimada S. Dendritic cells transduced with autoantigen FCRLA induce cytotoxic lymphocytes and vaccinate against murine B-cell lymphoma. The Journal of Investigative Dermatology. 127: 2818-22. PMID 17625599 DOI: 10.1038/sj.jid.5700909  0.445
2007 Ueda R, Yoshida K, Kawase T, Kawakami Y, Toda M. Preferential expression and frequent IgG responses of a tumor antigen, SOX5, in glioma patients. International Journal of Cancer. Journal International Du Cancer. 120: 1704-11. PMID 17230535 DOI: 10.1002/ijc.22472  0.545
2007 Takahashi H, Amagai M, Tanikawa A, Suzuki S, Ikeda Y, Nishikawa T, Kawakami Y, Kuwana M. T helper type 2-biased natural killer cell phenotype in patients with pemphigus vulgaris Journal of Investigative Dermatology. 127: 324-330. PMID 16946717 DOI: 10.1038/sj.jid.5700527  0.341
2006 Udagawa M, Kudo-Saito C, Hasegawa G, Yano K, Yamamoto A, Yaguchi M, Toda M, Azuma I, Iwai T, Kawakami Y. Enhancement of immunologic tumor regression by intratumoral administration of dendritic cells in combination with cryoablative tumor pretreatment and Bacillus Calmette-Guerin cell wall skeleton stimulation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 7465-75. PMID 17189420 DOI: 10.1158/1078-0432.CCR-06-1840  0.581
2006 Kuwana M, Okazaki Y, Kodama H, Satoh T, Kawakami Y, Ikeda Y. Endothelial differentiation potential of human monocyte-derived multipotential cells Stem Cells. 24: 2733-2743. PMID 16888284 DOI: 10.1634/stemcells.2006-0026  0.336
2006 Sumimoto H, Imabayashi F, Iwata T, Kawakami Y. The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells Journal of Experimental Medicine. 203: 1651-1656. PMID 16801397 DOI: 10.1084/jem.20051848  0.366
2006 Goto Y, Matsuzaki Y, Kurihara S, Shimizu A, Okada T, Yamamoto K, Murata H, Takata M, Aburatani H, Hoon DS, Saida T, Kawakami Y. A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Research. 66: 4443-9. PMID 16618771 DOI: 10.1158/0008-5472.CAN-05-2505  0.428
2006 Kodama H, Inoue T, Watanabe R, Yasutomi D, Kawakami Y, Ogawa S, Mikoshiba K, Ikeda Y, Kuwana M. Neurogenic potential of progenitors derived from human circulating CD14+ monocytes. Immunology and Cell Biology. 84: 209-17. PMID 16519739 DOI: 10.1111/j.1440-1711.2006.01424.x  0.307
2006 otani S, Sakurai T, Yamamoto K, Fujita T, Matsuzaki Y, Goto Y, Ando Y, Suzuki S, Usui M, Takeuchi M, Kawakami Y. Frequent immune response to a melanocyte specific protein KU-MEL-1 in patients with Vogt-Koyanagi-Harada disease. British Journal of Ophthalmology. 90: 773-777. PMID 16481377 DOI: 10.1136/Bjo.2005.086520  0.385
2006 Okada T, Akada M, Fujita T, Iwata T, Goto Y, Kido K, Okada T, Matsuzaki Y, Kobayashi K, Matsuno S, Sunamura M, Kawakami Y. A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 191-7. PMID 16397042 DOI: 10.1158/1078-0432.CCR-05-1206  0.352
2006 Matsushita M, Yamazaki R, Ikeda H, Mori T, Sumimoto H, Fujita T, Okamoto S, Ikeda Y, Kawakami Y. Possible involvement of allogeneic antigens recognised by donor-derived CD4 cytotoxic T cells in selective GVL effects after stem cell transplantation of patients with haematological malignancy. British Journal of Haematology. 132: 56-65. PMID 16371020 DOI: 10.1111/j.1365-2141.2005.05843.x  0.415
2006 Yoshiura K, Nakaoka T, Nishishita T, Sato K, Yamamoto A, Shimada S, Saida T, Kawakami Y, Takahashi TA, Fukuda H, Imajoh-Ohmi S, Oyaizu N, Yamashita N. Carbonic anhydrase II is a tumor vessel endothelium-associated antigen targeted by dendritic cell therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8201-7. PMID 16299253 DOI: 10.1158/1078-0432.CCR-05-0816  0.419
2006 Ohnishi M, Sakurai T, Heike Y, Yamazaki R, Kanda Y, Takaue Y, Mizoguchi H, Kawakami Y. Evaluation of cytomegalovirus-specific T-cell reconstitution in patients after various allogeneic haematopoietic stem cell transplantation using interferon-gamma-enzyme-linked immunospot and human leucocyte antigen tetramer assays with an immunodominant T-cell epitope. British Journal of Haematology. 131: 472-9. PMID 16281937 DOI: 10.1111/j.1365-2141.2005.05800.x  0.389
2006 Nakamura M, Tanaka Y, Satoh T, Kawai M, Hirakata M, Kaburaki J, Kawakami Y, Ikeda Y, Kuwana M. Autoantibody to CD40 ligand in systemic lupus erythematosus: association with thrombocytopenia but not thromboembolism Rheumatology. 45: 150-156. PMID 16188945 DOI: 10.1093/Rheumatology/Kei118  0.303
2006 Iizuka Y, Kojima H, Kobata T, Kawase T, Kawakami Y, Toda M. Identification of a glioma antigen, GARC-1, using cytotoxic T lymphocytes induced by HSV cancer vaccine. International Journal of Cancer. Journal International Du Cancer. 118: 942-9. PMID 16152596 DOI: 10.1002/ijc.21432  0.664
2006 Sumimoto H, Hirata K, Yamagata S, Miyoshi H, Miyagishi M, Taira K, Kawakami Y. Effective inhibition of cell growth and invasion of melanoma by combined suppression of BRAF (V599E) and Skp2 with lentiviral RNAi. International Journal of Cancer. 118: 472-6. PMID 16052531 DOI: 10.1002/ijc.21286  0.378
2006 Goto Y, Koyanagi K, Tanemura A, Matsuzaki Y, Kawakami Y, Morton D, Hoon D. The detection of fatty acid-binding protein 7 (FABP7) expression in melanoma tumors and circulating melanoma cells in blood Melanoma Research. 16: S51-S52. DOI: 10.1097/00008390-200609001-00092  0.353
2006 Sumimoto H, Kawakami Y. The Role of the Activated MAPK Pathway through the Oncogenic BRAFV600E-Mutation in the Immune Escaping Mechanism of Melanoma Molecular Therapy. 13: S237. DOI: 10.1016/j.ymthe.2006.08.689  0.33
2006 Iwata T, Sumimoto H, Mizuguchi H, Kawakami Y. 422. Enhancement of Human Monocyte-Derived Dendritic Cell Functions by Adenovirus- Mediated RNA Interference of STAT-3 Molecular Therapy. 13: S162. DOI: 10.1016/j.ymthe.2006.08.487  0.389
2006 Kido K, Sumimoto H, Asada S, Okada S, Saida T, Kawakami Y. 963. MITF as a Potential Molecular Target for Gene Therapy for Human Melanoma; a Synergistic Inhibitory Effect of Inactivation of Both MITF and BRAFV600E on Melanoma Growth Molecular Therapy. 13: S371. DOI: 10.1016/j.ymthe.2006.08.1055  0.376
2005 Kodama H, Inoue T, Watanabe R, Yasuoka H, Kawakami Y, Ogawa S, Ikeda Y, Mikoshiba K, Kuwana M. Cardiomyogenic potential of mesenchymal progenitors derived from human circulating CD14+ monocytes. Stem Cells and Development. 14: 676-86. PMID 16433623 DOI: 10.1089/scd.2005.14.676  0.311
2005 Kawakami Y, Sumimoto H, Fujita T, Matsuzaki Y. Immunological detection of altered signaling molecules involved in melanoma development. Cancer Metastasis Reviews. 24: 357-66. PMID 15986143 DOI: 10.1007/s10555-005-1583-y  0.449
2005 Iwata T, Fujita T, Hirao N, Matsuzaki Y, Okada T, Mochimaru H, Susumu N, Matsumoto E, Sugano K, Yamashita N, Nozawa S, Kawakami Y. Frequent immune responses to a cancer/testis antigen, CAGE, in patients with microsatellite instability-positive endometrial cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3949-57. PMID 15897597 DOI: 10.1158/1078-0432.CCR-04-1702  0.361
2005 Kawakami Y. [Identification of human tumor antigens recognized by T cells]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 562-7. PMID 15861711  0.323
2005 Okada T, Noji S, Goto Y, Iwata T, Fujita T, Okada T, Matsuzaki Y, Kuwana M, Hirakata M, Horii A, Matsuno S, Sunamura M, Kawakami Y. Immune responses to DNA mismatch repair enzymes hMSH2 and hPMS1 in patients with pancreatic cancer, dermatomyositis and polymyositis. International Journal of Cancer. 116: 925-33. PMID 15856462 DOI: 10.1002/ijc.21118  0.384
2005 Matsuzaki Y, Hashimoto S, Fujita T, Suzuki T, Sakurai T, Matsushima K, Kawakami Y. Systematic identification of human melanoma antigens using serial analysis of gene expression (SAGE). Journal of Immunotherapy (Hagerstown, Md. : 1997). 28: 10-9. PMID 15614040 DOI: 10.1097/00002371-200501000-00002  0.389
2005 Inozume T, Matsuzaki Y, Kurihara S, Fujita T, Yamamoto A, Aburatani H, Shimada S, Kawakami Y. Novel melanoma antigen, FCRL/FREB, identified by cDNA profile comparison using DNA chip are immunogenic in multiple melanoma patients. International Journal of Cancer. 114: 283-90. PMID 15551350 DOI: 10.1002/ijc.20735  0.404
2005 Satoh T, Kimura K, Okano Y, Hirakata M, Kawakami Y, Kuwana M. Lack of circulating autoantibodies to bone morphogenetic protein receptor-II or activin receptor-like kinase 1 in mixed connective tissue disease patients with pulmonary arterial hypertension Rheumatology. 44: 192-196. PMID 15509626 DOI: 10.1093/Rheumatology/Keh449  0.309
2005 Tanami H, Imoto I, Hirasawa A, Yuki Y, Sonoda I, Inoue J, Yasui K, Misawa-Furihata A, Kawakami Y, Inazawa J. Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines. Oncogene. 23: 8796-804. PMID 15467732 DOI: 10.1038/sj.onc.1208152  0.318
2005 Sumimoto H, Yamagata S, Shimizu A, Miyoshi H, Mizuguchi H, Hayakawa T, Miyagishi M, Taira K, Kawakami Y. Gene therapy for human small-cell lung carcinoma by inactivation of Skp-2 with virally mediated RNA interference Gene Therapy. 12: 95-100. PMID 15385954 DOI: 10.1038/Sj.Gt.3302391  0.382
2005 Miyagishi M, Sumimoto H, Miyoshi H, Kawakami Y, Taira K. Optimization of an siRNA-expression system with an improved hairpin and its significant suppressive effects in mammalian cells. The Journal of Gene Medicine. 6: 715-23. PMID 15241778 DOI: 10.1002/jgm.556  0.304
2005 Sumimoto H, Miyagishi M, Miyoshi H, Yamagata S, Shimizu A, Taira K, Kawakami Y. Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference. Oncogene. 23: 6031-9. PMID 15208655 DOI: 10.1038/sj.onc.1207812  0.33
2005 Kuwana M, Kawakami Y, Ikeda Y. Splenic Macrophages Maintain the Anti-Platelet Autoimmune Response Via Uptake of Opsonized Platelets in Patients with Chronic ITP. Blood. 106: 221-221. DOI: 10.1182/BLOOD.V106.11.221.221  0.386
2004 Ueda R, Yoshida K, Kawakami Y, Kawase T, Toda M. Immunohistochemical analysis of SOX6 expression in human brain tumors. Brain Tumor Pathology. 21: 117-20. PMID 15696972 DOI: 10.1007/BF02482186  0.553
2004 Ueda R, Yoshida K, Kawakami Y, Kawase T, Toda M. Expression of a transcriptional factor, SOX6, in human gliomas. Brain Tumor Pathology. 21: 35-8. PMID 15696967 DOI: 10.1007/BF02482175  0.537
2004 Yasuoka H, Okazaki Y, Kawakami Y, Hirakata M, Inoko H, Ikeda Y, Kuwana M. Autoreactive CD8+ cytotoxic T lymphocytes to major histocompatibility complex class I chain-related gene A in patients with Behçet's disease. Arthritis and Rheumatism. 50: 3658-62. PMID 15529349 DOI: 10.1002/ART.20597  0.347
2004 Kawakami Y, Fujita T, Matsuzaki Y, Sakurai T, Tsukamoto M, Toda M, Sumimoto H. Identification of human tumor antigens and its implications for diagnosis and treatment of cancer. Cancer Science. 95: 784-91. PMID 15504244 DOI: 10.1111/j.1349-7006.2004.tb02182.x  0.607
2004 Kuwana M, Matsuura E, Kobayashi K, Okazaki Y, Kaburaki J, Ikeda Y, Kawakami Y. Binding of beta 2-glycoprotein I to anionic phospholipids facilitates processing and presentation of a cryptic epitope that activates pathogenic autoreactive T cells. Blood. 105: 1552-7. PMID 15486070 DOI: 10.1182/BLOOD-2004-08-3145  0.333
2004 Ohashi Y, Ueda M, Kawase T, Kawakami Y, Toda M. Identification of an epigenetically silenced gene, RFX1, in human glioma cells using restriction landmark genomic scanning. Oncogene. 23: 7772-9. PMID 15334059 DOI: 10.1038/sj.onc.1208058  0.606
2004 Kawakami Y. [Development of immunotherapy for cancer: lessons from melanoma research]. Nihon Rinsho Men'Eki Gakkai Kaishi = Japanese Journal of Clinical Immunology. 27: 87-98. PMID 15164929 DOI: 10.2177/JSCI.27.87  0.467
2004 Mikami Y, Okano H, Sakaguchi M, Nakamura M, Shimazaki T, Okano HJ, Kawakami Y, Toyama Y, Toda M. Implantation of dendritic cells in injured adult spinal cord results in activation of endogenous neural stem/progenitor cells leading to de novo neurogenesis and functional recovery. Journal of Neuroscience Research. 76: 453-65. PMID 15114617 DOI: 10.1002/Jnr.20086  0.467
2004 Kawakami Y, Okada T, Akada M. Development of immunotherapy for pancreatic cancer. Pancreas. 28: 320-5. PMID 15084980 DOI: 10.1097/00006676-200404000-00021  0.463
2004 Satoh T, Pandey JP, Okazaki Y, Yasuoka H, Kawakami Y, Ikeda Y, Kuwana M. Single nucleotide polymorphisms of the inflammatory cytokine genes in adults with chronic immune thrombocytopenic purpura. British Journal of Haematology. 124: 796-801. PMID 15009068 DOI: 10.1111/j.1365-2141.2004.04843.x  0.3
2004 Iizuka Y, Suzuki A, Kawakami Y, Toda M. Augmentation of antitumor immune responses by multiple intratumoral inoculations of replication-conditional HSV and interleukin-12. Journal of Immunotherapy (Hagerstown, Md. : 1997). 27: 92-8. PMID 14770080 DOI: 10.1097/00002371-200403000-00002  0.617
2004 Ito K, Fujita T, Akada M, Kiniwa Y, Tsukamoto M, Yamamoto A, Matsuzaki Y, Matsushita M, Asano T, Nakashima J, Tachibana M, Hayakawa M, Ikeda H, Murai M, Kawakami Y. Identification of bladder cancer antigens recognized by IgG antibodies of a patient with metastatic bladder cancer. International Journal of Cancer. 108: 712-24. PMID 14696098 DOI: 10.1002/ijc.11625  0.411
2004 Ueda R, Iizuka Y, Yoshida K, Kawase T, Kawakami Y, Toda M. Identification of a human glioma antigen, SOX6, recognized by patients' sera. Oncogene. 23: 1420-7. PMID 14691456 DOI: 10.1038/sj.onc.1207252  0.646
2004 Yasuoka H, Ihn H, Medsger TA, Hirakata M, Kawakami Y, Ikeda Y, Kuwana M. A novel protein highly expressed in testis is overexpressed in systemic sclerosis fibroblasts and targeted by autoantibodies. Journal of Immunology (Baltimore, Md. : 1950). 171: 6883-90. PMID 14662895 DOI: 10.4049/jimmunol.171.12.6883  0.326
2004 Nagayama H, Sato K, Morishita M, Uchimaru K, Oyaizu N, Inazawa T, Yamasaki T, Enomoto M, Nakaoka T, Nakamura T, Maekawa T, Yamamoto A, Shimada S, Saida T, Kawakami Y, et al. Results of a phase I clinical study using autologous tumour lysate-pulsed monocyte-derived mature dendritic cell vaccinations for stage IV malignant melanoma patients combined with low dose interleukin-2. Melanoma Research. 13: 521-30. PMID 14512794 DOI: 10.1097/00008390-200310000-00011  0.383
2004 Kuwana M, Kodama H, Okazaki Y, Satoh T, Inoue T, Kawakami Y, Ikeda Y. Multi-Lineage Potential of Human Monocyte-Derived Mesenchymal Progenitors (MOMPs). Blood. 104: 3595-3595. DOI: 10.1182/blood.v104.11.3595.3595  0.355
2004 Onishi M, Sakurai T, Heike Y, Kanda Y, Takaue Y, Mizoguchi H, Kawakami Y. Measurement of Functional Cytomegalovirus (CMV)-Specific T Cells by Interferon-gamma-Enzyme-Linked Immunospot (IFN-g ELISPOT) Assay Specific for a Single Immunodominant Epitope Enables the Sensitive Evaluation of Immune Recovery for CMV in Patients after Allogeneic Stem Cell Transplantation (HSCT) with a Reduced-Intensity Regimen (RIST). Blood. 104: 3157-3157. DOI: 10.1182/Blood.V104.11.3157.3157  0.386
2004 Yamazaki R, Kuwana M, Okazaki Y, Kawakami Y, Ikeda Y, Okamoto S. Impaired Platelet Production and Autoantibody-Mediated Platelet Destruction Are Two Major Causes for Prolonged Thrombocytopenia after Allogeneic HSCT. Blood. 104: 2256-2256. DOI: 10.1182/blood.v104.11.2256.2256  0.301
2004 Ito K, Fujita T, Tsukamoto M, Matsuzaki Y, Asano T, Nakashima J, Hayakawa M, Murai M, Kawakami Y. 740: Identification of Bladder Cancer Antigens Recognized by IGG Antibodies of a Patient with Metastatic Bladder Cancer Journal of Urology. 171: 196-197. DOI: 10.1016/s0022-5347(18)37989-8  0.337
2004 Sumimoto H, Yamagata S, Shimizu A, Miyagishi M, Miyoshi H, Taira K, Kawakami Y. 1028. Virus-Mediated RNAi for Skp-2 in Human Small Cell Lung Carcinoma Cells Resulted in the Inhibition of Tumor Cell Growth through the Increase of p27Kip1 and p21 Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.973  0.401
2003 Ishikawa T, Fujita T, Suzuki Y, Okabe S, Yuasa Y, Iwai T, Kawakami Y. Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability. Cancer Research. 63: 5564-72. PMID 14500396  0.333
2003 Kuwana M, Okazaki Y, Kodama H, Izumi K, Yasuoka H, Ogawa Y, Kawakami Y, Ikeda Y. Human circulating CD14+ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation. Journal of Leukocyte Biology. 74: 833-45. PMID 12960274 DOI: 10.1189/jlb.0403170  0.333
2003 Kawakami Y. Identification of human tumor antigens recognized by T-cells and their use for immunotherapy. International Journal of Hematology. 77: 427-34. PMID 12841379 DOI: 10.1007/BF02986609  0.47
2003 Kajihara M, Kato S, Okazaki Y, Kawakami Y, Ishii H, Ikeda Y, Kuwana M. A role of autoantibody-mediated platelet destruction in thrombocytopenia in patients with cirrhosis. Hepatology (Baltimore, Md.). 37: 1267-76. PMID 12774004 DOI: 10.1053/jhep.2003.50209  0.304
2003 Ogawa Y, Kuwana M, Yamazaki K, Mashima Y, Yamada M, Mori T, Okamoto S, Oguchi Y, Kawakami Y. Periductal area as the primary site for T-cell activation in lacrimal gland chronic graft-versus-host disease. Investigative Ophthalmology & Visual Science. 44: 1888-96. PMID 12714620 DOI: 10.1167/IOVS.02-0699  0.329
2003 Matsushita M, Yamazaki R, Ikeda H, Kawakami Y. Preferentially expressed antigen of melanoma (PRAME) in the development of diagnostic and therapeutic methods for hematological malignancies. Leukemia & Lymphoma. 44: 439-44. PMID 12688312 DOI: 10.1080/1042819021000035725  0.47
2003 Suzuki S, Tanaka K, Yasuoka H, Fukuuchi Y, Kawakami Y, Kuwana M. Autoreactive T cells to the P3A+ isoform of AChR α subunit in myasthenia gravis Journal of Neuroimmunology. 137: 177-186. PMID 12667662 DOI: 10.1016/S0165-5728(03)00078-X  0.346
2003 Ogawa Y, Kuwana M, Yamazaki K, Mashima Y, Okamoto S, Tsubota K, Oguchi Y, Kawakami Y. Dry eye associated with chronic graft-versus-host disease. Advances in Experimental Medicine and Biology. 506: 1041-5. PMID 12614029 DOI: 10.1007/978-1-4615-0717-8_147  0.317
2003 Sumimoto H, Tsuji T, Miyoshi H, Hagihara M, Takada-Yamazaki R, Okamoto S, Ikeda Y, Takahashi T, Kawakami Y. Rapid and efficient generation of lentivirally gene-modified dendritic cells from DC progenitors with bone marrow stromal cells. Journal of Immunological Methods. 271: 153-65. PMID 12445738 DOI: 10.1016/S0022-1759(02)00342-3  0.354
2002 Kuwana M, Kawakami Y, Ikeda Y. Suppression of autoreactive T-cell response to glycoprotein IIb/IIIa by blockade of CD40/CD154 interaction: implications for treatment of immune thrombocytopenic purpura. Blood. 101: 621-3. PMID 12393517 DOI: 10.1182/BLOOD-2002-07-2157  0.367
2002 Kuwana M, Kimura K, Hirakata M, Kawakami Y, Ikeda Y. Differences in autoantibody response to Th/To between systemic sclerosis and other autoimmune diseases Annals of the Rheumatic Diseases. 61: 842-846. PMID 12176814 DOI: 10.1136/Ard.61.9.842  0.312
2002 Mikami Y, Toda M, Watanabe M, Nakamura M, Toyama Y, Kawakami Y. A simple and reliable behavioral analysis of locomotor function after spinal cord injury in mice. Technical note. Journal of Neurosurgery. 97: 142-7. PMID 12120639 DOI: 10.3171/Spi.2002.97.1.0142  0.408
2002 Toda M, Iizuka Y, Kawase T, Uyemura K, Kawakami Y. Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional HSV. Cancer Gene Therapy. 9: 356-64. PMID 11960286 DOI: 10.1038/sj.cgt.7700446  0.72
2002 Kuwana M, Okazaki Y, Kaburaki J, Kawakami Y, Ikeda Y. Spleen is a primary site for activation of platelet-reactive T and B cells in patients with immune thrombocytopenic purpura. Journal of Immunology (Baltimore, Md. : 1950). 168: 3675-82. PMID 11907134 DOI: 10.4049/jimmunol.168.7.3675  0.381
2002 Yoshida K, Arai T, Kaburaki J, Ikeda Y, Kawakami Y, Kuwana M. Restricted T-cell receptor beta-chain usage by T cells autoreactive to beta(2)-glycoprotein I in patients with antiphospholipid syndrome. Blood. 99: 2499-504. PMID 11895785 DOI: 10.1182/BLOOD.V99.7.2499  0.316
2002 Endo T, Toda M, Watanabe M, Iizuka Y, Kubota T, Kitajima M, Kawakami Y. In situ cancer vaccination with a replication-conditional HSV for the treatment of liver metastasis of colon cancer. Cancer Gene Therapy. 9: 142-8. PMID 11857031 DOI: 10.1038/sj.cgt.7700407  0.61
2001 Ishii K, Toda M, Nakai Y, Asou H, Watanabe M, Nakamura M, Yato Y, Fujimura Y, Kawakami Y, Toyama Y, Uyemura K. Increase of oligodendrocyte progenitor cells after spinal cord injury. Journal of Neuroscience Research. 65: 500-7. PMID 11550218 DOI: 10.1002/jnr.1180  0.597
2001 Kuwana M, Kaburaki J, Wright TM, Kawakami Y, Ikeda Y. Induction of antigen-specific human CD4(+) T cell anergy by peripheral blood DC2 precursors. European Journal of Immunology. 31: 2547-57. PMID 11536152 DOI: 10.1002/1521-4141(200109)31:9<2547::AID-IMMU2547>3.0.CO;2-J  0.403
2001 Arai T, Yoshida K, Kaburaki J, Inoko H, Ikeda Y, Kawakami Y, Kuwana M. Autoreactive CD4(+) T-cell clones to beta2-glycoprotein I in patients with antiphospholipid syndrome: preferential recognition of the major phospholipid-binding site. Blood. 98: 1889-96. PMID 11535526 DOI: 10.1182/BLOOD.V98.6.1889  0.398
2001 Kuwana M, Kaburaki J, Kitasato H, Kato M, Kawai S, Kawakami Y, Ikeda Y. Immunodominant epitopes on glycoprotein IIb-IIIa recognized by autoreactive T cells in patients with immune thrombocytopenic purpura. Blood. 98: 130-9. PMID 11418472 DOI: 10.1182/BLOOD.V98.1.130  0.415
2001 Matsushita M, Ikeda H, Kizaki M, Okamoto S, Ogasawara M, Ikeda Y, Kawakami Y. Quantitative monitoring of the PRAME gene for the detection of minimal residual disease in leukaemia. British Journal of Haematology. 112: 916-926. PMID 11298586 DOI: 10.1046/J.1365-2141.2001.02670.X  0.42
2001 Toda M, Iizuka Y, Yu W, Imai T, Ikeda E, Yoshida K, Kawase T, Kawakami Y, Okano H, Uyemura K. Expression of the neural RNA-binding protein Musashi1 in human gliomas. Glia. 34: 1-7. PMID 11284014 DOI: 10.1002/Glia.1034  0.729
2001 Toda I, Kuwana M, Tsubota K, Kawakami Y. Lack of evidence for an increased microchimerism in the circulation of patients with Sjögren's syndrome Annals of the Rheumatic Diseases. 60: 248-253. PMID 11171687 DOI: 10.1136/Ard.60.3.248  0.308
2001 Kawakami Y, Wang X, Shofuda T, Sumimoto H, Tupesis J, Fitzgerald E, Rosenberg S. Isolation of a new melanoma antigen, MART-2, containing a mutated epitope recognized by autologous tumor-infiltrating T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 166: 2871-7. PMID 11160356 DOI: 10.4049/jimmunol.166.4.2871  0.532
2001 Kageshita T, Kawakami Y, Ono T. Clinical significance of MART-1 and HLA-A2 expression and CD8+ T cell infiltration in melanocytic lesions in HLA-A2 phenotype patients. Journal of Dermatological Science. 25: 36-44. PMID 11154862 DOI: 10.1016/S0923-1811(00)00104-3  0.374
2001 Kawakami Y, Suzuki Y, Shofuda T, Kiniwa Y, Inozume T, Dan K, Sakurai T, Fujita T. T cell immune responses against melanoma and melanocytes in cancer and autoimmunity. Pigment Cell Research. 163-9. PMID 11041376 DOI: 10.1034/J.1600-0749.13.S8.29.X  0.471
2000 Kuwana M, Kaburaki J, Pandey JP, Murata M, Kawakami Y, Inoko H, Ikeda Y. HLA class II alleles in Japanese patients with immune thrombocytopenic purpura. Associations with anti-platelet glycoprotein autoantibodies and responses to splenectomy. Tissue Antigens. 56: 337-43. PMID 11098933 DOI: 10.1034/j.1399-0039.2000.560405.x  0.314
2000 Kawakami Y. New cancer therapy by immunomanipulation: development of immunotherapy for human melanoma as a model system. Cornea. 19: S2-6. PMID 10832714 DOI: 10.1097/00003226-200005001-00002  0.473
2000 Kuwana M, Kaburaki J, Mimori T, Kawakami Y, Tojo T. Longitudinal analysis of autoantibody response to topoisomerase I in systemic sclerosis. Arthritis and Rheumatism. 43: 1074-84. PMID 10817562 DOI: 10.1002/1529-0131(200005)43:5<1074::AID-ANR18>3.0.CO;2-E  0.314
2000 Kawakami Y, Dang N, Wang X, Tupesis J, Robbins PF, Wang RF, Wunderlich JR, Yannelli JR, Rosenberg SA. Recognition of shared melanoma antigens in association with major HLA-A alleles by tumor infiltrating T lymphocytes from 123 patients with melanoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 17-27. PMID 10687134 DOI: 10.1097/00002371-200001000-00004  0.452
2000 Hattori N, Kuwana M, Kaburaki J, Mimori T, Ikeda Y, Kawakami Y. T cells that are autoreactive to beta2-glycoprotein I in patients with antiphospholipid syndrome and healthy individuals. Arthritis and Rheumatism. 43: 65-75. PMID 10643701 DOI: 10.1002/1529-0131(200001)43:1<65::AID-ANR9>3.0.CO;2-I  0.319
2000 Kuwana M, Kawakami Y, Ikeda Y. Identification and characterization of pathogenic autoreactive T cells in patients with idiopathic thrombocytopenic purpura Japanese Journal of Clinical Immunology. 23: 555-557. DOI: 10.2177/Jsci.23.555  0.348
2000 Ogawa Y, Kuwana M, Yamazaki K, Mashima Y, Okamoto S, Oguchi Y, Tsubota K, Kawakami Y. CO-LOCALIZATION OF T CELLS WITH STROMAL FIBROBLASTS EXPRESSING HLA-DR AND CD54 IN THE LACRIMAL GLAND FROM PATIENTS WITH CHRONIC GRAFT-VERSUS-HOST DISEASE (cGVHD). Cornea. 19: S111. DOI: 10.1097/00003226-200011002-00136  0.35
2000 Kawakami Y. Immunotherapy of Melanoma Using T-Cell-Defined Antigens The Keio Journal of Medicine. 48: 77-92. DOI: 10.1007/978-4-431-68506-7_7  0.471
1998 Kawakami Y, Robbins PF, Wang RF, Parkhurst M, Kang X, Rosenberg SA. The use of melanosomal proteins in the immunotherapy of melanoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 237-46. PMID 9672845 DOI: 10.1097/00002371-199807000-00001  0.564
1998 Rosenberg SA, Yang JC, Schwartzentruber DJ, Hwu P, Marincola FM, Topalian SL, Restifo NP, Dudley ME, Schwarz SL, Spiess PJ, Wunderlich JR, Parkhurst MR, Kawakami Y, Seipp CA, Einhorn JH, et al. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nature Medicine. 4: 321-7. PMID 9500606 DOI: 10.1038/Nm0398-321  0.484
1998 Kawakami Y. Immunotherapy Using T Cell Defined Tumor Antigens for Melanoma Microbiology and Immunology. 42: 803-813. DOI: 10.1111/j.1348-0421.1998.tb02355.x  0.439
1997 Kawakami Y, Rosenberg SA. Human tumor antigens recognized by T-cells. Immunologic Research. 16: 313-39. PMID 9439758 DOI: 10.1007/BF02786397  0.573
1997 Kageshita T, Kawakami Y, Hirai S, Ono T. Differential expression of MART-1 in primary and metastatic melanoma lesions. Journal of Immunotherapy. 20: 460-465. PMID 9409451 DOI: 10.1097/00002371-199711000-00005  0.308
1997 Sakai C, Kawakami Y, Law LW, Furumura M, Hearing VJ. Melanosomal proteins as melanoma-specific immune targets Melanoma Research. 7: 83-95. PMID 9167173 DOI: 10.1097/00008390-199704000-00001  0.323
1997 Kawakami Y, Rosenberg SA. Immunobiology of human melanoma antigens MART-1 and gp100 and their use for immuno-gene therapy. International Reviews of Immunology. 14: 173-92. PMID 9131386 DOI: 10.3109/08830189709116851  0.566
1997 Kawakami Y, Battles JK, Kobayashi T, Ennis W, Wang X, Tupesis JP, Marincola FM, Robbins PF, Hearing VJ, Gonda MA, Rosenberg SA. Production of recombinant MART-1 proteins and specific antiMART-1 polyclonal and monoclonal antibodies: use in the characterization of the human melanoma antigen MART-1. Journal of Immunological Methods. 202: 13-25. PMID 9075767 DOI: 10.1016/S0022-1759(96)00211-6  0.473
1996 Wang RF, Appella E, Kawakami Y, Kang X, Rosenberg SA. Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes. The Journal of Experimental Medicine. 184: 2207-16. PMID 8976176 DOI: 10.1084/jem.184.6.2207  0.466
1996 Kawakami Y, Rosenberg SA. T-cell recognition of self peptides as tumor rejection antigens. Immunologic Research. 15: 179-90. PMID 8902575 DOI: 10.1007/Bf02918248  0.538
1996 Robbins PF, Kawakami Y. Human tumor antigens recognized by T cells Current Opinion in Immunology. 8: 628-636. PMID 8902387 DOI: 10.1016/S0952-7915(96)80078-1  0.439
1996 Rosenberg SA, Kawakami Y, Robbins PF, Wang R. Identification of the genes encoding cancer antigens: implications for cancer immunotherapy. Advances in Cancer Research. 70: 145-77. PMID 8902056 DOI: 10.1016/S0065-230X(08)60874-X  0.539
1996 Marincola FM, Hijazi YM, Fetsch P, Salgaller ML, Rivoltini L, Cormier J, Simonis TB, Duray PH, Herlyn M, Kawakami Y, Rosenberg SA. Analysis of expression of the melanoma-associated antigens MART-1 and gp100 in metastatic melanoma cell lines and in in situ lesions. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 19: 192-205. PMID 8811494 DOI: 10.1097/00002371-199605000-00004  0.542
1996 Kawakami Y, Robbins PF, Rosenberg SA. Human melanoma antigens recognized by T lymphocytes. The Keio Journal of Medicine. 45: 100-8. PMID 8683899 DOI: 10.2302/Kjm.45.100  0.568
1996 Robbins PF, El-Gamil M, Li YF, Kawakami Y, Loftus D, Appella E, Rosenberg SA. A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes. The Journal of Experimental Medicine. 183: 1185-92. PMID 8642260 DOI: 10.1084/jem.183.3.1185  0.532
1996 Wang RF, Parkhurst MR, Kawakami Y, Robbins PF, Rosenberg SA. Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen. The Journal of Experimental Medicine. 183: 1131-40. PMID 8642255 DOI: 10.1084/Jem.183.3.1131  0.561
1996 Restifo NP, Marincola FM, Kawakami Y, Taubenberger J, Yannelli JR, Rosenberg SA. Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy. Journal of the National Cancer Institute. 88: 100-8. PMID 8537970 DOI: 10.1093/Jnci/88.2.100  0.537
1995 Yannelli JR, McConnell S, Parker L, Nishimura M, Robbins P, Yang J, Gamil ME, Kawakami Y. Melanoma tumor-infiltrating lymphocytes derived from four distinct anatomic sites obtained from a single patient: Comparison of functional reactivity and melanoma antigen recognition Journal of Immunotherapy. 18: 263-271. PMID 8680654  0.318
1995 Wang RF, Robbins PF, Kawakami Y, Kang XQ, Rosenberg SA. Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes. The Journal of Experimental Medicine. 181: 799-804. PMID 7836932 DOI: 10.1084/JEM.181.2.799  0.555
1995 Sanda MG, Restifo NP, Walsh JC, Kawakami Y, Nelson WG, Pardoll DM, Simons JW. Molecular characterization of defective antigen processing in human prostate cancer. Journal of the National Cancer Institute. 87: 280-5. PMID 7707419 DOI: 10.1093/Jnci/87.4.280  0.378
1995 Bakker AB, Schreurs MW, Tafazzul G, de Boer AJ, Kawakami Y, Adema GJ, Figdor CG. Identification of a novel peptide derived from the melanocyte-specific gp100 antigen as the dominant epitope recognized by an HLA-A2.1-restricted anti-melanoma CTL line. International Journal of Cancer. 62: 97-102. PMID 7541395 DOI: 10.1002/IJC.2910620118  0.367
1994 Kawakami Y, Eliyahu S, Delgado CH, Robbins PF, Rivoltini L, Topalian SL, Miki T, Rosenberg SA. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proceedings of the National Academy of Sciences of the United States of America. 91: 3515-9. PMID 8170938 DOI: 10.1073/PNAS.91.9.3515  0.564
1994 Bakker AB, Schreurs MW, de Boer AJ, Kawakami Y, Rosenberg SA, Adema GJ, Figdor CG. Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes. The Journal of Experimental Medicine. 179: 1005-9. PMID 8113668 DOI: 10.1084/JEM.179.3.1005  0.509
1994 Kawakami Y, Eliyahu S, Delgado CH, Robbins PF, Sakaguchi K, Appella E, Yannelli JR, Adema GJ, Miki T, Rosenberg SA. Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proceedings of the National Academy of Sciences of the United States of America. 91: 6458-62. PMID 8022805 DOI: 10.1073/PNAS.91.14.6458  0.552
1994 Topalian SL, Rivoltini L, Mancini M, Markus NR, Robbins PF, Kawakami Y, Rosenberg SA. Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 9461-5. PMID 7937789 DOI: 10.1073/PNAS.91.20.9461  0.564
1994 Nishimura MI, Kawakami Y, Charmley P, O'Neil B, Shilyansky J, Yannelli JR, Rosenberg SA, Hood L. T-cell receptor repertoire in tumor-infiltrating lymphocytes. Analysis of melanoma-specific long-term lines. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 16: 85-94. PMID 7804531 DOI: 10.1097/00002371-199408000-00002  0.507
1994 Shamamian P, Mancini M, Kawakami Y, Restifo NP, Rosenberg SA, Topalian SL. Recognition of neuroectodermal tumors by melanoma-specific cytotoxic T lymphocytes: evidence for antigen sharing by tumors derived from the neural crest Cancer Immunology Immunotherapy. 39: 73-83. PMID 7519127 DOI: 10.1007/Bf01525312  0.567
1994 Kawakami Y, Eliyahu S, Sakaguchi K, Robbins PF, Rivoltini L, Yannelli JR, Appella E, Rosenberg SA. Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes. The Journal of Experimental Medicine. 180: 347-52. PMID 7516411 DOI: 10.1084/JEM.180.1.347  0.482
1994 Shilyansky J, Nishimura MI, Yannelli JR, Kawakami Y, Jacknin LS, Charmley P, Rosenberg SA. T-cell receptor usage by melanoma-specific clonal and highly oligoclonal tumor-infiltrating lymphocyte lines. Proceedings of the National Academy of Sciences of the United States of America. 91: 2829-33. PMID 7511820 DOI: 10.1073/Pnas.91.7.2829  0.554
1993 Restifo NP, Esquivel F, Kawakami Y, Yewdell JW, Mulé JJ, Rosenberg SA, Bennink JR. Identification of human cancers deficient in antigen processing Journal of Experimental Medicine. 177: 265-272. PMID 8426105 DOI: 10.1084/Jem.177.2.265  0.543
1993 Restifo NP, Kawakami Y, Marincola F, Shamamian P, Taggarse A, Esquivel F, Rosenberg SA. Molecular mechanisms used by tumors to escape immune recognition: Immunogenetherapy and the cell biology of major histocompatibility complex class I Journal of Immunotherapy. 14: 182-190. PMID 8297900 DOI: 10.1097/00002371-199310000-00004  0.533
1993 Kawakami Y, Nishimura MI, Restifo NP, Topalian SL, O'Neil BH, Shilyansky J, Yannelli JR, Rosenberg SA. T-cell recognition of human melanoma antigens. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 14: 88-93. PMID 8280705 DOI: 10.1097/00002371-199308000-00002  0.532
1993 Restifo NP, Esquivel F, Kawakami Y, Yewdell JW, Mulé JJ, Rosenberg SA, Bennink JR. IDENTIFICATION OF HUMAN CANCERS DEFECTIVE IN ANTIGEN PROCESSING Journal of Immunotherapy. 13: 70. DOI: 10.1097/00002371-199301000-00051  0.444
1992 Topalian SL, Hom SS, Kawakami Y, Mancini M, Schwartzentruber DJ, Zakut R, Rosenberg SA. Recognition of shared melanoma antigens by human tumor-infiltrating lymphocytes. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 12: 203-6. PMID 1445813 DOI: 10.1097/00002371-199210000-00013  0.536
1991 Klein TW, Kawakami Y, Newton C, Friedman H. Marijuana components suppress induction and cytolytic function of murine cytotoxic T cells in vitro and in vivo. Journal of Toxicology and Environmental Health. 32: 465-477. PMID 1850002 DOI: 10.1080/15287399109531496  0.388
1990 Lotze MT, Custer MC, Bolton ES, Wiebke EA, Kawakami Y, Rosenberg SA. Mechanisms of immunologic antitumor therapy: lessons from the laboratory and clinical applications. Human Immunology. 28: 198-207. PMID 2190952 DOI: 10.1016/0198-8859(90)90020-P  0.544
1989 Specter S, Rivenbark M, Newton C, Kawakami Y, Lancz G. Prevention and reversal of delta-9-tetrahydrocannabinol induced depression of natural killer cell activity by interleukin-2 International Journal of Immunopharmacology. 11: 63-69. PMID 2540100 DOI: 10.1016/0192-0561(89)90100-8  0.329
1988 Kawakami Y, Rosenberg SA, Lotze MT. Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma Journal of Experimental Medicine. 168: 2183-2191. PMID 3264324 DOI: 10.1084/jem.168.6.2183  0.432
1988 Kawakami Y, Klein TW, Newton C, Djeu JY, Specter S, Friedman H. Suppression by delta-9-tetrahydrocannabinol of interleukin 2-induced lymphocyte proliferation and lymphokine-activated killer cell activity International Journal of Immunopharmacology. 10: 485-488. PMID 2844686 DOI: 10.1016/0192-0561(88)90137-3  0.353
1988 Kawakami Y, Klein TW, Newton C, Djeu JY, Specter S, Friedman H, Dennert G. Suppression by Cannabinoids of a Cloned Cell Line with Natural Killer Cell Activity Proceedings of the Society For Experimental Biology and Medicine. 187: 355-359. PMID 2831542 DOI: 10.3181/00379727-187-42676  0.349
1988 Kawakami Y, Klein TW, Newton CA, Young J, Friedman H. Suppression by cannabinoids of the induction and function of murine cytotoxic T lymphocytes International Journal of Immunopharmacology. 10: 147. DOI: 10.1016/0192-0561(88)90531-0  0.308
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