Steven A. Rosenberg - Publications

Affiliations: 
NCI/NIH, Bethesda, MD, United States 

490 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Paria BC, Levin N, Lowery FJ, Pasetto A, Deniger DC, Parkhurst MR, Yossef R, Kim SP, Florentin M, Ngo LT, Ray S, Krishna S, Robbins PF, Rosenberg SA. Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). PMID 33086340 DOI: 10.1097/CJI.0000000000000342  0.56
2020 Cafri G, Gartner JJ, Zaks T, Hopson K, Levin N, Paria BC, Parkhurst MR, Yossef R, Lowery FJ, Jafferji MS, Prickett TD, Goff SL, McGowan CT, Seitter S, Shindorf ML, ... ... Rosenberg SA, et al. mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer. The Journal of Clinical Investigation. PMID 33016924 DOI: 10.1172/JCI134915  0.56
2020 Sachs A, Moore E, Kosaloglu-Yalcin Z, Peters B, Sidney J, Rosenberg SA, Robbins PF, Sette A. Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32571843 DOI: 10.4049/jimmunol.1901173  0.56
2020 Malekzadeh P, Yossef R, Cafri G, Paria BC, Lowery FJ, Jafferji M, Good ML, Sachs A, Copeland AR, Kim SP, Kivitz S, Parkhurst MR, Robbins PF, Ray S, Xi L, ... ... Rosenberg SA, et al. Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31996390 DOI: 10.1158/1078-0432.CCR-19-1874  0.56
2020 Zhang L, Davies JS, Serna C, Yu Z, Restifo NP, Rosenberg SA, Morgan RA, Hinrichs CS. Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models. Journal For Immunotherapy of Cancer. 8. PMID 31959727 DOI: 10.1136/jitc-2019-000210  0.4
2019 Gros A, Tran E, Parkhurst MR, Ilyas S, Pasetto A, Groh EM, Robbins PF, Yossef R, Garcia-Garijo A, Fajardo CA, Prickett TD, Jia L, Gartner JJ, Ray S, Ngo L, ... ... Rosenberg SA, et al. Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes. The Journal of Clinical Investigation. PMID 31609250 DOI: 10.1172/JCI127967  0.56
2019 Lu YC, Jia L, Zheng Z, Tran E, Robbins PF, Rosenberg SA. Single-cell transcriptome analysis reveals gene signatures associated with T-cell persistence following adoptive cell therapy. Cancer Immunology Research. PMID 31484655 DOI: 10.1158/2326-6066.CIR-19-0299  0.56
2019 Parkhurst MR, Robbins PF, Tran E, Prickett TD, Gartner JJ, Jia L, Ivey G, Li YF, El-Gamil M, Lalani A, Crystal JS, Sachs A, Groh EM, Ray S, Ngo LT, ... ... Rosenberg SA, et al. Unique neoantigens arise from somatic mutations in patients with gastrointestinal cancers. Cancer Discovery. PMID 31164343 DOI: 10.1158/2159-8290.CD-18-1494  0.56
2019 Goff SL, Morgan RA, Yang JC, Sherry RM, Robbins PF, Restifo NP, Feldman SA, Lu YC, Lu L, Zheng Z, Xi L, Epstein M, McIntyre LS, Malekzadeh P, Raffeld M, ... ... Rosenberg SA, et al. Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). PMID 30882547 DOI: 10.1097/CJI.0000000000000260  0.56
2019 Malekzadeh P, Pasetto A, Robbins PF, Parkhurst MR, Paria BC, Jia L, Gartner JJ, Hill V, Yu Z, Restifo NP, Sachs A, Tran E, Lo W, Somerville RP, Rosenberg SA, et al. Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers. The Journal of Clinical Investigation. PMID 30714987 DOI: 10.1172/JCI123791  0.56
2019 Lo W, Parkhurst MR, Robbins PF, Tran E, Lu YC, Jia L, Gartner JJ, Pasetto A, Deniger DC, Malekzadeh P, Shelton T, Prickett TD, Ray S, Kivitz S, Paria BC, ... ... Rosenberg SA, et al. Immunologic recognition of a shared p53 mutated neoantigen in a patient with metastatic colorectal cancer. Cancer Immunology Research. PMID 30709841 DOI: 10.1158/2326-6066.CIR-18-0686  0.56
2019 Cafri G, Yossef R, Pasetto A, Deniger DC, Lu YC, Parkhurst M, Gartner JJ, Jia L, Ray S, Ngo LT, Jafferji M, Sachs A, Prickett T, Robbins PF, Rosenberg SA. Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients. Nature Communications. 10: 449. PMID 30683863 DOI: 10.1038/s41467-019-08304-z  0.56
2019 Ahmadzadeh M, Pasetto A, Jia L, Deniger DC, Stevanović S, Robbins PF, Rosenberg SA. Tumor-infiltrating human CD4 regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity. Science Immunology. 4. PMID 30635355 DOI: 10.1126/sciimmunol.aao4310  0.56
2018 Yossef R, Tran E, Deniger DC, Gros A, Pasetto A, Parkhurst MR, Gartner JJ, Prickett TD, Cafri G, Robbins PF, Rosenberg SA. Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy. Jci Insight. 3. PMID 30282837 DOI: 10.1172/jci.insight.122467  0.56
2018 Zacharakis N, Chinnasamy H, Black M, Xu H, Lu YC, Zheng Z, Pasetto A, Langhan M, Shelton T, Prickett T, Gartner J, Jia L, Trebska-McGowan K, Somerville RP, Robbins PF, ... Rosenberg SA, et al. Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer. Nature Medicine. PMID 29867227 DOI: 10.1038/s41591-018-0040-8  0.56
2018 Deniger DC, Pasetto A, Robbins PF, Gartner JJ, Prickett TD, Paria BC, Malekzadeh P, Jia L, Yossef R, Langhan MM, Wunderlich JR, Danforth DN, Somerville RPT, Rosenberg SA. T-cell responses to "hotspot" mutations and unique neoantigens expressed by human ovarian cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29853601 DOI: 10.1158/1078-0432.CCR-18-0573  0.56
2018 Jin BY, Campbell TE, Draper LM, Stevanović S, Weissbrich B, Yu Z, Restifo NP, Rosenberg SA, Trimble CL, Hinrichs CS. Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model. Jci Insight. 3. PMID 29669936 DOI: 10.1172/jci.insight.99488  0.4
2017 Lu YC, Zheng Z, Robbins PF, Tran E, Prickett TD, Gartner JJ, Li YF, Ray S, Franco Z, Bliskovsky V, Fitzgerald PC, Rosenberg SA. An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29174843 DOI: 10.1016/j.ymthe.2017.10.018  0.56
2017 Lu YC, Parker LL, Lu T, Zheng Z, Toomey MA, White DE, Yao X, Li YF, Robbins PF, Feldman SA, van der Bruggen P, Klebanoff CA, Goff SL, Sherry RM, Kammula US, ... ... Rosenberg SA, et al. Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017745463. PMID 28809608 DOI: 10.1200/JCO.2017.74.5463  0.56
2017 Stevanović S, Pasetto A, Helman SR, Gartner JJ, Prickett TD, Howie B, Robins HS, Robbins PF, Klebanoff CA, Rosenberg SA, Hinrichs CS. Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer. Science (New York, N.Y.). 356: 200-205. PMID 28408606 DOI: 10.1126/science.aak9510  0.56
2017 Assadipour Y, Zacharakis N, Crystal JS, Prickett TD, Gartner JJ, Somerville RP, Xu H, Black MA, Jia L, Chinnasamy H, Kriley I, Lu L, Wunderlich JR, Zheng Z, Lu YC, ... ... Rosenberg SA, et al. Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple Negative Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28377481 DOI: 10.1158/1078-0432.CCR-16-1423  0.56
2017 Rosenberg SA, Tran E, Robbins PF. T-Cell Transfer Therapy Targeting Mutant KRAS. The New England Journal of Medicine. 376: e11. PMID 28199803 DOI: 10.1056/NEJMc1616637  0.56
2017 Tran E, Robbins PF, Rosenberg SA. 'Final common pathway' of human cancer immunotherapy: targeting random somatic mutations. Nature Immunology. 18: 255-262. PMID 28198830 DOI: 10.1038/ni.3682  0.56
2016 Slaney CY, von Scheidt B, Davenport AJ, Beavis P, Westwood JA, Mardiana S, Tscharke D, Ellis S, Prince HM, Trapani JA, Johnstone RW, Smyth MJ, Teng MW, Ali A, Yu Z, ... Rosenberg SA, et al. Dual-specific chimeric antigen receptor T cells and an indirect vaccine eradicate a variety of large solid tumors in an immunocompetent, self-antigen setting. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27965307 DOI: 10.1158/1078-0432.CCR-16-1860  0.4
2016 Tran E, Robbins PF, Lu YC, Prickett TD, Gartner JJ, Jia L, Pasetto A, Zheng Z, Ray S, Groh EM, Kriley IR, Rosenberg SA. T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer. The New England Journal of Medicine. 375: 2255-2262. PMID 27959684 DOI: 10.1056/NEJMoa1609279  0.56
2016 Parkhurst MR, Gros A, Pasetto A, Prickett TD, Crystal JS, Robbins PF, Rosenberg SA. Isolation of T cell receptors specifically reactive with mutated tumor associated antigens from tumor infiltrating lymphocytes based on CD137 expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27827318 DOI: 10.1158/1078-0432.CCR-16-2680  0.56
2016 Pasetto A, Alena G, Robbins PF, Deniger DC, Prickett TD, Matus-Nicodemos R, Douek DC, Howie B, Robins H, Parkhurst MR, Gartner JJ, Trebska-McGowan K, Crystal JS, Rosenberg SA. Tumor- and neoantigen-reactive T-cell receptors can be identified based on their frequency in fresh tumor. Cancer Immunology Research. PMID 27354337 DOI: 10.1158/2326-6066.CIR-16-0001  0.56
2016 Prickett TD, Crystal JS, Cohen CJ, Pasetto A, Parkhurst MR, Gartner JJ, Yao X, Wang R, Gros A, Li YF, El-Gamil M, Trebska-McGowan K, Rosenberg SA, Robbins PF. Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor Antigens. Cancer Immunology Research. PMID 27312342 DOI: 10.1158/2326-6066.CIR-15-0215  0.44
2016 Goff SL, Dudley ME, Citrin DE, Somerville RP, Wunderlich JR, Danforth DN, Zlott DA, Yang JC, Sherry RM, Kammula US, Klebanoff CA, Hughes MS, Restifo NP, Langhan MM, Shelton TE, ... ... Rosenberg SA, et al. Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27217459 DOI: 10.1200/JCO.2016.66.7220  0.44
2016 Yao X, Lu YC, Parker LL, Li YF, El-Gamil M, Black MA, Xu H, Feldman SA, van der Bruggen P, Rosenberg SA, Robbins PF. Isolation and Characterization of an HLA-DPB1*04: 01-restricted MAGE-A3 T-Cell Receptor for Cancer Immunotherapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 39: 191-201. PMID 27163739 DOI: 10.1097/CJI.0000000000000123  0.44
2016 Deniger DC, Pasetto A, Tran E, Parkhurst MR, Cohen CJ, Robbins PF, Cooper LJ, Rosenberg SA. Stable, non-viral expression of mutated tumor neoantigen-specific T-cell receptors using the Sleeping Beauty transposon/transposase system. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26945006 DOI: 10.1038/mt.2016.51  0.44
2016 Jaigirdar A, Rosenberg SA, Parkhurst M. A High-avidity WT1-reactive T-Cell Receptor Mediates Recognition of Peptide and Processed Antigen but not Naturally Occurring WT1-positive Tumor Cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). PMID 26938944 DOI: 10.1097/CJI.0000000000000116  0.44
2016 Gros A, Parkhurst MR, Tran E, Pasetto A, Robbins PF, Ilyas S, Prickett TD, Gartner JJ, Crystal JS, Roberts IM, Trebska-McGowan K, Wunderlich JR, Yang JC, Rosenberg SA. Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients. Nature Medicine. PMID 26901407 DOI: 10.1038/nm.4051  0.44
2016 Brudno JN, Somerville RP, Shi V, Rose JJ, Halverson DC, Fowler DH, Gea-Banacloche JC, Pavletic SZ, Hickstein DD, Lu TL, Feldman SA, Iwamoto AT, Kurlander R, Maric I, Goy A, ... ... Rosenberg SA, et al. Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host Disease. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26811520 DOI: 10.1200/JCO.2015.64.5929  0.44
2016 Klebanoff CA, Rosenberg SA, Restifo NP. Prospects for gene-engineered T cell immunotherapy for solid cancers. Nature Medicine. 22: 26-36. PMID 26735408 DOI: 10.1038/nm.4015  0.4
2016 Yang JC, Rosenberg SA. Adoptive T-Cell Therapy for Cancer Advances in Immunology. DOI: 10.1016/bs.ai.2015.12.006  0.44
2015 Rosenberg SA. CCR 20th Anniversary Commentary: Autologous T Cells-The Ultimate Personalized Drug for the Immunotherapy of Human Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 5409-11. PMID 26672082 DOI: 10.1158/1078-0432.CCR-14-3131  0.44
2015 Klebanoff CA, Scott CD, Leonardi AJ, Yamamoto TN, Cruz AC, Ouyang C, Ramaswamy M, Roychoudhuri R, Ji Y, Eil RL, Sukumar M, Crompton JG, Palmer DC, Borman ZA, Clever D, ... ... Rosenberg SA, et al. Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy. The Journal of Clinical Investigation. PMID 26657860 DOI: 10.1172/JCI81217  0.4
2015 Tran E, Ahmadzadeh M, Lu YC, Gros A, Turcotte S, Robbins PF, Gartner JJ, Zheng Z, Li YF, Ray S, Wunderlich JR, Somerville RP, Rosenberg SA. Immunogenicity of somatic mutations in human gastrointestinal cancers. Science (New York, N.Y.). PMID 26516200 DOI: 10.1126/science.aad1253  0.44
2015 Arafeh R, Qutob N, Emmanuel R, Keren-Paz A, Madore J, Elkahloun A, Wilmott JS, Gartner JJ, Di Pizio A, Winograd-Katz S, Sindiri S, Rotkopf R, Dutton-Regester K, Johansson P, Pritchard AL, ... ... Rosenberg SA, et al. Recurrent inactivating RASA2 mutations in melanoma. Nature Genetics. PMID 26502337 DOI: 10.1038/ng.3427  0.44
2015 Draper LM, Kwong ML, Gros A, Stevanović S, Tran E, Kerkar S, Raffeld M, Rosenberg SA, Hinrichs CS. Targeting of HPV-16+ Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 4431-9. PMID 26429982 DOI: 10.1158/1078-0432.CCR-14-3341  0.44
2015 Cohen CJ, Gartner JJ, Horovitz-Fried M, Shamalov K, Trebska-McGowan K, Bliskovsky VV, Parkhurst MR, Ankri C, Prickett TD, Crystal JS, Li YF, El-Gamil M, Rosenberg SA, Robbins PF. Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes. The Journal of Clinical Investigation. PMID 26389673 DOI: 10.1172/JCI82416  0.44
2015 Feldman SA, Assadipour Y, Kriley I, Goff SL, Rosenberg SA. Adoptive Cell Therapy-Tumor-Infiltrating Lymphocytes, T-Cell Receptors, and Chimeric Antigen Receptors. Seminars in Oncology. 42: 626-39. PMID 26320066 DOI: 10.1053/j.seminoncol.2015.05.005  0.44
2015 Beane JD, Lee G, Zheng Z, Mendel M, Abate-Daga D, Bharathan M, Black M, Gandhi N, Yu Z, Chandran S, Giedlin M, Ando D, Miller J, Paschon D, Guschin D, ... ... Rosenberg SA, et al. Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 25939491 DOI: 10.1038/mt.2015.71  0.44
2015 Liu L, Patel B, Ghanem MH, Bundoc V, Zheng Z, Morgan RA, Rosenberg SA, Dey B, Berger EA. Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor Activity. Journal of Virology. 89: 6685-94. PMID 25878112 DOI: 10.1128/JVI.00474-15  0.44
2015 Rosenberg SA, Restifo NP. Adoptive cell transfer as personalized immunotherapy for human cancer. Science (New York, N.Y.). 348: 62-8. PMID 25838374 DOI: 10.1126/science.aaa4967  0.44
2015 Stevanovi? S, Draper LM, Langhan MM, Campbell TE, Kwong ML, Wunderlich JR, Dudley ME, Yang JC, Sherry RM, Kammula US, Restifo NP, Rosenberg SA, Hinrichs CS. Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 1543-50. PMID 25823737 DOI: 10.1200/JCO.2014.58.9093  0.44
2015 Zhang L, Morgan RA, Beane JD, Zheng Z, Dudley ME, Kassim SH, Nahvi AV, Ngo LT, Sherry RM, Phan GQ, Hughes MS, Kammula US, Feldman SA, Toomey MA, Kerkar SP, ... ... Rosenberg SA, et al. Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2278-88. PMID 25695689 DOI: 10.1158/1078-0432.CCR-14-2085  0.44
2015 Robbins PF, Kassim SH, Tran TL, Crystal JS, Morgan RA, Feldman SA, Yang JC, Dudley ME, Wunderlich JR, Sherry RM, Kammula US, Hughes MS, Restifo NP, Raffeld M, Lee CC, ... ... Rosenberg SA, et al. A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1019-27. PMID 25538264 DOI: 10.1158/1078-0432.CCR-14-2708  0.44
2015 Crompton JG, Sukumar M, Roychoudhuri R, Clever D, Gros A, Eil RL, Tran E, Hanada K, Yu Z, Palmer DC, Kerkar SP, Michalek RD, Upham T, Leonardi A, Acquavella N, ... ... Rosenberg SA, et al. Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics. Cancer Research. 75: 296-305. PMID 25432172 DOI: 10.1158/0008-5472.CAN-14-2277  0.44
2015 Conlon KC, Lugli E, Welles HC, Rosenberg SA, Fojo AT, Morris JC, Fleisher TA, Dubois SP, Perera LP, Stewart DM, Goldman CK, Bryant BR, Decker JM, Chen J, Worthy TA, et al. Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 74-82. PMID 25403209 DOI: 10.1200/JCO.2014.57.3329  0.44
2015 Lee DW, Kochenderfer JN, Stetler-Stevenson M, Cui YK, Delbrook C, Feldman SA, Fry TJ, Orentas R, Sabatino M, Shah NN, Steinberg SM, Stroncek D, Tschernia N, Yuan C, Zhang H, ... ... Rosenberg SA, et al. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial. Lancet (London, England). 385: 517-28. PMID 25319501 DOI: 10.1016/S0140-6736(14)61403-3  0.44
2015 Kochenderfer JN, Dudley ME, Kassim SH, Somerville RP, Carpenter RO, Stetler-Stevenson M, Yang JC, Phan GQ, Hughes MS, Sherry RM, Raffeld M, Feldman S, Lu L, Li YF, Ngo LT, ... ... Rosenberg SA, et al. Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 540-9. PMID 25154820 DOI: 10.1200/JCO.2014.56.2025  0.44
2015 Topalian SL, Wolchok JD, Chan TA, Mellman I, Palucka K, Banchereau J, Rosenberg SA, Wittrup KD. Immunotherapy: The path to win the war on cancer? Cell. 161: 185-186. DOI: 10.1016/j.cell.2015.03.045  0.44
2014 Stevanovic S, Draper L, Somerville R, Wunderlich J, Restifo NP, Sherry R, Giao PQ, Kammula US, Yang JC, Rosenberg SA. HPV-targeted tumor-infiltrating lymphocytes for cervical cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: LBA3008. PMID 28141973 DOI: 10.1200/jco.2014.32.18_suppl.lba3008  0.4
2014 Rosenberg SA. Decade in review-cancer immunotherapy: entering the mainstream of cancer treatment. Nature Reviews. Clinical Oncology. 11: 630-2. PMID 25311350 DOI: 10.1038/nrclinonc.2014.174  0.44
2014 Beard RE, Zheng Z, Lagisetty KH, Burns WR, Tran E, Hewitt SM, Abate-Daga D, Rosati SF, Fine HA, Ferrone S, Rosenberg SA, Morgan RA. Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells. Journal For Immunotherapy of Cancer. 2: 25. PMID 25197555 DOI: 10.1186/2051-1426-2-25  0.44
2014 Corrigan-Curay J, Kiem HP, Baltimore D, O'Reilly M, Brentjens RJ, Cooper L, Forman S, Gottschalk S, Greenberg P, Junghans R, Heslop H, Jensen M, Mackall C, June C, Press O, ... ... Rosenberg S, et al. T-cell immunotherapy: looking forward. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1564-74. PMID 25186558 DOI: 10.1038/mt.2014.148  0.44
2014 Walia V, Prickett TD, Kim JS, Gartner JJ, Lin JC, Zhou M, Rosenberg SA, Elble RC, Solomon DA, Waldman T, Samuels Y. Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma. Human Mutation. 35: 1301-10. PMID 25113440 DOI: 10.1002/humu.22630  0.44
2014 Abate-Daga D, Rosenberg SA, Morgan RA. Pancreatic cancer: Hurdles in the engineering of CAR-based immunotherapies. Oncoimmunology. 3: e29194. PMID 25083334 DOI: 10.4161/onci.29194  0.44
2014 Feldman SA, Xu H, Black MA, Park TS, Robbins PF, Kochenderfer JN, Morgan RA, Rosenberg SA. Use of the piggyBac transposon to create stable packaging cell lines for the production of clinical-grade self-inactivating γ-retroviral vectors. Human Gene Therapy Methods. 25: 253-60. PMID 25072603 DOI: 10.1089/hgtb.2014.071  0.44
2014 Malecek K, Grigoryan A, Zhong S, Gu WJ, Johnson LA, Rosenberg SA, Cardozo T, Krogsgaard M. Specific increase in potency via structure-based design of a TCR. Journal of Immunology (Baltimore, Md. : 1950). 193: 2587-99. PMID 25070852 DOI: 10.4049/jimmunol.1302344  0.44
2014 Tran E, Rosenberg SA. T-cell therapy against cancer mutations. Oncotarget. 5: 4579-80. PMID 25046408  0.44
2014 Lu YC, Yao X, Crystal JS, Li YF, El-Gamil M, Gross C, Davis L, Dudley ME, Yang JC, Samuels Y, Rosenberg SA, Robbins PF. Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3401-10. PMID 24987109 DOI: 10.1158/1078-0432.CCR-14-0433  0.44
2014 Dutton-Regester K, Gartner JJ, Emmanuel R, Qutob N, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Scolyer RA, Mann GJ, Thompson JF, Hayward NK, Samuels Y. A highly recurrent RPS27 5'UTR mutation in melanoma. Oncotarget. 5: 2912-7. PMID 24913145  0.44
2014 Rosenberg SA. IL-2: the first effective immunotherapy for human cancer. Journal of Immunology (Baltimore, Md. : 1950). 192: 5451-8. PMID 24907378 DOI: 10.4049/jimmunol.1490019  0.44
2014 Tran E, Turcotte S, Gros A, Robbins PF, Lu YC, Dudley ME, Wunderlich JR, Somerville RP, Hogan K, Hinrichs CS, Parkhurst MR, Yang JC, Rosenberg SA. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer. Science (New York, N.Y.). 344: 641-5. PMID 24812403 DOI: 10.1126/science.1251102  0.44
2014 Beane JD, Yang JC, White D, Steinberg SM, Rosenberg SA, Rudloff U. Efficacy of adjuvant radiation therapy in the treatment of soft tissue sarcoma of the extremity: 20-year follow-up of a randomized prospective trial. Annals of Surgical Oncology. 21: 2484-9. PMID 24756814 DOI: 10.1245/s10434-014-3732-4  0.44
2014 Prickett TD, Zerlanko BJ, Hill VK, Gartner JJ, Qutob N, Jiang J, Simaan M, Wunderlich J, Gutkind JS, Rosenberg SA, Samuels Y. Somatic mutation of GRIN2A in malignant melanoma results in loss of tumor suppressor activity via aberrant NMDAR complex formation. The Journal of Investigative Dermatology. 134: 2390-8. PMID 24739903 DOI: 10.1038/jid.2014.190  0.44
2014 Yang JC, Sherry RM, Rosenberg SA. Melanoma: Why is sentinel lymph node biopsy 'standard of care' for melanoma? Nature Reviews. Clinical Oncology. 11: 245-6. PMID 24732941 DOI: 10.1038/nrclinonc.2014.65  0.44
2014 Abate-Daga D, Lagisetty KH, Tran E, Zheng Z, Gattinoni L, Yu Z, Burns WR, Miermont AM, Teper Y, Rudloff U, Restifo NP, Feldman SA, Rosenberg SA, Morgan RA. A novel chimeric antigen receptor against prostate stem cell antigen mediates tumor destruction in a humanized mouse model of pancreatic cancer. Human Gene Therapy. 25: 1003-12. PMID 24694017 DOI: 10.1089/hum.2013.209  0.44
2014 Liu Q, Tomei S, Ascierto ML, De Giorgi V, Bedognetti D, Dai C, Uccellini L, Spivey T, Pos Z, Thomas J, Reinboth J, Murtas D, Zhang Q, Chouchane L, Weiss GR, ... ... Rosenberg SA, et al. Melanoma NOS1 expression promotes dysfunctional IFN signaling. The Journal of Clinical Investigation. 124: 2147-59. PMID 24691438 DOI: 10.1172/JCI69611  0.44
2014 Abate-Daga D, Speiser DE, Chinnasamy N, Zheng Z, Xu H, Feldman SA, Rosenberg SA, Morgan RA. Development of a T cell receptor targeting an HLA-A*0201 restricted epitope from the cancer-testis antigen SSX2 for adoptive immunotherapy of cancer. Plos One. 9: e93321. PMID 24681846 DOI: 10.1371/journal.pone.0093321  0.44
2014 Gros A, Robbins PF, Yao X, Li YF, Turcotte S, Tran E, Wunderlich JR, Mixon A, Farid S, Dudley ME, Hanada K, Almeida JR, Darko S, Douek DC, Yang JC, ... Rosenberg SA, et al. PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors. The Journal of Clinical Investigation. 124: 2246-59. PMID 24667641 DOI: 10.1172/JCI73639  0.44
2014 Bartlett EK, Fetsch PA, Filie AC, Abati A, Steinberg SM, Wunderlich JR, White DE, Stephens DJ, Marincola FM, Rosenberg SA, Kammula US. Human melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2607-16. PMID 24647571 DOI: 10.1158/1078-0432.CCR-13-2690  0.44
2014 Rosati SF, Parkhurst MR, Hong Y, Zheng Z, Feldman SA, Rao M, Abate-Daga D, Beard RE, Xu H, Black MA, Robbins PF, Schrump DA, Rosenberg SA, Morgan RA. A novel murine T-cell receptor targeting NY-ESO-1. Journal of Immunotherapy (Hagerstown, Md. : 1997). 37: 135-46. PMID 24598449 DOI: 10.1097/CJI.0000000000000019  0.44
2014 Rosenberg SA. Finding suitable targets is the major obstacle to cancer gene therapy. Cancer Gene Therapy. 21: 45-7. PMID 24535159 DOI: 10.1038/cgt.2014.3  0.44
2014 Tseng J, Citrin DE, Waldman M, White DE, Rosenberg SA, Yang JC. Thrombotic microangiopathy in metastatic melanoma patients treated with adoptive cell therapy and total body irradiation. Cancer. 120: 1426-32. PMID 24474396 DOI: 10.1002/cncr.28547  0.44
2014 Sampson JH, Choi BD, Sanchez-Perez L, Suryadevara CM, Snyder DJ, Flores CT, Schmittling RJ, Nair SK, Reap EA, Norberg PK, Herndon JE, Kuan CT, Morgan RA, Rosenberg SA, Johnson LA. EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 972-84. PMID 24352643 DOI: 10.1158/1078-0432.CCR-13-0709  0.44
2014 Hinrichs CS, Rosenberg SA. Exploiting the curative potential of adoptive T-cell therapy for cancer. Immunological Reviews. 257: 56-71. PMID 24329789 DOI: 10.1111/imr.12132  0.44
2014 Aung PP, Liu YC, Ballester LY, Robbins PF, Rosenberg SA, Lee CC. Expression of New York esophageal squamous cell carcinoma-1 in primary and metastatic melanoma. Human Pathology. 45: 259-67. PMID 24290058 DOI: 10.1016/j.humpath.2013.05.029  0.44
2014 Turcotte S, Gros A, Tran E, Lee CC, Wunderlich JR, Robbins PF, Rosenberg SA. Tumor-reactive CD8+ T cells in metastatic gastrointestinal cancer refractory to chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 331-43. PMID 24218514 DOI: 10.1158/1078-0432.CCR-13-1736  0.44
2014 Liu B, Zhong S, Malecek K, Johnson LA, Rosenberg SA, Zhu C, Krogsgaard M. 2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system. European Journal of Immunology. 44: 239-50. PMID 24114747 DOI: 10.1002/eji.201343774  0.44
2014 Prickett TD, Zerlanko B, Gartner JJ, Parker SC, Dutton-Regester K, Lin JC, Teer JK, Wei X, Jiang J, Chen G, Davies MA, Gershenwald JE, Robinson W, Robinson S, ... ... Rosenberg SA, et al. Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin. The Journal of Investigative Dermatology. 134: 452-60. PMID 24008424 DOI: 10.1038/jid.2013.365  0.44
2013 Bedognetti D, Spivey TL, Zhao Y, Uccellini L, Tomei S, Dudley ME, Ascierto ML, De Giorgi V, Liu Q, Delogu LG, Sommariva M, Sertoli MR, Simon R, Wang E, Rosenberg SA, et al. CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2. British Journal of Cancer. 109: 2412-23. PMID 24129241 DOI: 10.1038/bjc.2013.557  0.44
2013 Chen S, Li Y, Depontieu FR, McMiller TL, English AM, Shabanowitz J, Kos F, Sidney J, Sette A, Rosenberg SA, Hunt DF, Mariuzza RA, Topalian SL. Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity. Journal of Immunology (Baltimore, Md. : 1950). 191: 5097-106. PMID 24108701 DOI: 10.4049/jimmunol.1300467  0.44
2013 Phan GQ, Rosenberg SA. Adoptive cell transfer for patients with metastatic melanoma: the potential and promise of cancer immunotherapy. Cancer Control : Journal of the Moffitt Cancer Center. 20: 289-97. PMID 24077405  0.44
2013 Kochenderfer JN, Dudley ME, Carpenter RO, Kassim SH, Rose JJ, Telford WG, Hakim FT, Halverson DC, Fowler DH, Hardy NM, Mato AR, Hickstein DD, Gea-Banacloche JC, Pavletic SZ, Sportes C, ... ... Rosenberg SA, et al. Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation. Blood. 122: 4129-39. PMID 24055823 DOI: 10.1182/blood-2013-08-519413  0.44
2013 Beard RE, Abate-Daga D, Rosati SF, Zheng Z, Wunderlich JR, Rosenberg SA, Morgan RA. Gene expression profiling using nanostring digital RNA counting to identify potential target antigens for melanoma immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4941-50. PMID 24021875 DOI: 10.1158/1078-0432.CCR-13-1253  0.44
2013 Turcotte S, Gros A, Hogan K, Tran E, Hinrichs CS, Wunderlich JR, Dudley ME, Rosenberg SA. Phenotype and function of T cells infiltrating visceral metastases from gastrointestinal cancers and melanoma: implications for adoptive cell transfer therapy. Journal of Immunology (Baltimore, Md. : 1950). 191: 2217-25. PMID 23904171 DOI: 10.4049/jimmunol.1300538  0.44
2013 Casati A, Varghaei-Nahvi A, Feldman SA, Assenmacher M, Rosenberg SA, Dudley ME, Scheffold A. Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients. Cancer Immunology, Immunotherapy : Cii. 62: 1563-73. PMID 23903715 DOI: 10.1007/s00262-013-1459-x  0.44
2013 Gartner JJ, Parker SC, Prickett TD, Dutton-Regester K, Stitzel ML, Lin JC, Davis S, Simhadri VL, Jha S, Katagiri N, Gotea V, Teer JK, Wei X, Morken MA, Bhanot UK, ... ... Rosenberg SA, et al. Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma. Proceedings of the National Academy of Sciences of the United States of America. 110: 13481-6. PMID 23901115 DOI: 10.1073/pnas.1304227110  0.44
2013 Abate-Daga D, Hanada K, Davis JL, Yang JC, Rosenberg SA, Morgan RA. Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes. Blood. 122: 1399-410. PMID 23861247 DOI: 10.1182/blood-2013-04-495531  0.44
2013 Tran E, Chinnasamy D, Yu Z, Morgan RA, Lee CC, Restifo NP, Rosenberg SA. Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia. The Journal of Experimental Medicine. 210: 1125-35. PMID 23712432 DOI: 10.1084/jem.20130110  0.44
2013 Lu YC, Yao X, Li YF, El-Gamil M, Dudley ME, Yang JC, Almeida JR, Douek DC, Samuels Y, Rosenberg SA, Robbins PF. Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression. Journal of Immunology (Baltimore, Md. : 1950). 190: 6034-42. PMID 23690473 DOI: 10.4049/jimmunol.1202830  0.44
2013 Dudley ME, Gross CA, Somerville RP, Hong Y, Schaub NP, Rosati SF, White DE, Nathan D, Restifo NP, Steinberg SM, Wunderlich JR, Kammula US, Sherry RM, Yang JC, Phan GQ, ... ... Rosenberg SA, et al. Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2152-9. PMID 23650429 DOI: 10.1200/JCO.2012.46.6441  0.44
2013 Robbins PF, Lu YC, El-Gamil M, Li YF, Gross C, Gartner J, Lin JC, Teer JK, Cliften P, Tycksen E, Samuels Y, Rosenberg SA. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nature Medicine. 19: 747-52. PMID 23644516 DOI: 10.1038/nm.3161  0.44
2013 Chinnasamy D, Tran E, Yu Z, Morgan RA, Restifo NP, Rosenberg SA. Simultaneous targeting of tumor antigens and the tumor vasculature using T lymphocyte transfer synergize to induce regression of established tumors in mice. Cancer Research. 73: 3371-80. PMID 23633494 DOI: 10.1158/0008-5472.CAN-12-3913  0.44
2013 Zhong S, Malecek K, Johnson LA, Yu Z, Vega-Saenz de Miera E, Darvishian F, McGary K, Huang K, Boyer J, Corse E, Shao Y, Rosenberg SA, Restifo NP, Osman I, Krogsgaard M. T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 110: 6973-8. PMID 23576742 DOI: 10.1073/pnas.1221609110  0.44
2013 Kerkar SP, Leonardi AJ, van Panhuys N, Zhang L, Yu Z, Crompton JG, Pan JH, Palmer DC, Morgan RA, Rosenberg SA, Restifo NP. Collapse of the tumor stroma is triggered by IL-12 induction of Fas. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1369-77. PMID 23568260 DOI: 10.1038/mt.2013.58  0.44
2013 Kochenderfer JN, Rosenberg SA. Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors. Nature Reviews. Clinical Oncology. 10: 267-76. PMID 23546520 DOI: 10.1038/nrclinonc.2013.46  0.44
2013 Malecek K, Zhong S, McGary K, Yu C, Huang K, Johnson LA, Rosenberg SA, Krogsgaard M. Engineering improved T cell receptors using an alanine-scan guided T cell display selection system. Journal of Immunological Methods. 392: 1-11. PMID 23500145 DOI: 10.1016/j.jim.2013.02.018  0.44
2013 Morgan RA, Chinnasamy N, Abate-Daga D, Gros A, Robbins PF, Zheng Z, Dudley ME, Feldman SA, Yang JC, Sherry RM, Phan GQ, Hughes MS, Kammula US, Miller AD, Hessman CJ, ... ... Rosenberg SA, et al. Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 36: 133-51. PMID 23377668 DOI: 10.1097/CJI.0b013e3182829903  0.44
2013 Yang S, Ji Y, Gattinoni L, Zhang L, Yu Z, Restifo NP, Rosenberg SA, Morgan RA. Modulating the differentiation status of ex vivo-cultured anti-tumor T cells using cytokine cocktails. Cancer Immunology, Immunotherapy : Cii. 62: 727-36. PMID 23207483 DOI: 10.1007/s00262-012-1378-2  0.44
2013 Zhang L, Yu Z, Muranski P, Palmer DC, Restifo NP, Rosenberg SA, Morgan RA. Inhibition of TGF-β signaling in genetically engineered tumor antigen-reactive T cells significantly enhances tumor treatment efficacy. Gene Therapy. 20: 575-80. PMID 22972494 DOI: 10.1038/gt.2012.75  0.44
2012 Zhu S, Van den Eynde BJ, Coulie PG, Li YF, El-Gamil M, Rosenberg SA, Robbins PF. Characterization of T-cell receptors directed against HLA-A*01-restricted and C*07-restricted epitopes of MAGE-A3 and MAGE-A12. Journal of Immunotherapy (Hagerstown, Md. : 1997). 35: 680-8. PMID 23090077 DOI: 10.1097/CJI.0b013e31827338ea  0.44
2012 Gartner JJ, Davis S, Wei X, Lin JC, Trivedi NS, Teer JK, Meltzer PS, Rosenberg SA, Samuels Y. Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma. Bmc Genomics. 13: 505. PMID 23006843 DOI: 10.1186/1471-2164-13-505  0.44
2012 Wang A, Chandran S, Shah SA, Chiu Y, Paria BC, Aghamolla T, Alvarez-Downing MM, Lee CC, Singh S, Li T, Dudley ME, Restifo NP, Rosenberg SA, Kammula US. The stoichiometric production of IL-2 and IFN-γ mRNA defines memory T cells that can self-renew after adoptive transfer in humans. Science Translational Medicine. 4: 149ra120. PMID 22932225 DOI: 10.1126/scitranslmed.3004306  0.44
2012 Parker SC, Gartner J, Cardenas-Navia I, Wei X, Ozel Abaan H, Ajay SS, Hansen NF, Song L, Bhanot UK, Killian JK, Gindin Y, Walker RL, Meltzer PS, Mullikin JC, Furey TS, ... ... Rosenberg SA, et al. Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes. Plos Genetics. 8: e1002871. PMID 22912592 DOI: 10.1371/journal.pgen.1002871  0.44
2012 Uccellini L, De Giorgi V, Zhao Y, Tumaini B, Erdenebileg N, Dudley ME, Tomei S, Bedognetti D, Ascierto ML, Liu Q, Simon R, Kottyan L, Kaufman KM, Harley JB, Wang E, ... Rosenberg SA, et al. IRF5 gene polymorphisms in melanoma. Journal of Translational Medicine. 10: 170. PMID 22909381 DOI: 10.1186/1479-5876-10-170  0.44
2012 Gros A, Turcotte S, Wunderlich JR, Ahmadzadeh M, Dudley ME, Rosenberg SA. Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5212-23. PMID 22837179 DOI: 10.1158/1078-0432.CCR-12-1108  0.44
2012 June C, Rosenberg SA, Sadelain M, Weber JS. T-cell therapy at the threshold. Nature Biotechnology. 30: 611-4. PMID 22781680 DOI: 10.1038/nbt.2305  0.44
2012 Morgan RA, Johnson LA, Davis JL, Zheng Z, Woolard KD, Reap EA, Feldman SA, Chinnasamy N, Kuan CT, Song H, Zhang W, Fine HA, Rosenberg SA. Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma. Human Gene Therapy. 23: 1043-53. PMID 22780919 DOI: 10.1089/hum.2012.041  0.44
2012 Kvistborg P, Shu CJ, Heemskerk B, Fankhauser M, Thrue CA, Toebes M, van Rooij N, Linnemann C, van Buuren MM, Urbanus JH, Beltman JB, Thor Straten P, Li YF, Robbins PF, Besser MJ, ... ... Rosenberg SA, et al. TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients. Oncoimmunology. 1: 409-418. PMID 22754759  0.56
2012 Alvarez-Downing MM, Inchauste SM, Dudley ME, White DE, Wunderlich JR, Rosenberg SA, Kammula US. Minimally invasive liver resection to obtain tumor-infiltrating lymphocytes for adoptive cell therapy in patients with metastatic melanoma. World Journal of Surgical Oncology. 10: 113. PMID 22726267 DOI: 10.1186/1477-7819-10-113  0.44
2012 DeVita VT, Rosenberg SA. Two hundred years of cancer research. The New England Journal of Medicine. 366: 2207-14. PMID 22646510 DOI: 10.1056/NEJMra1204479  0.44
2012 Seaman BJ, Guardiani EA, Brewer CC, Zalewski CK, King KA, Rudy S, Van Waes C, Morgan RA, Dudley ME, Yang JC, Rosenberg SA, Kim HJ. Audiovestibular dysfunction associated with adoptive cell immunotherapy for melanoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 147: 744-9. PMID 22597578 DOI: 10.1177/0194599812448356  0.44
2012 Zhang L, Feldman SA, Zheng Z, Chinnasamy N, Xu H, Nahvi AV, Dudley ME, Rosenberg SA, Morgan RA. Evaluation of γ-retroviral vectors that mediate the inducible expression of IL-12 for clinical application. Journal of Immunotherapy (Hagerstown, Md. : 1997). 35: 430-9. PMID 22576348 DOI: 10.1097/CJI.0b013e31825898e8  0.44
2012 Friedman KM, Prieto PA, Devillier LE, Gross CA, Yang JC, Wunderlich JR, Rosenberg SA, Dudley ME. Tumor-specific CD4+ melanoma tumor-infiltrating lymphocytes. Journal of Immunotherapy (Hagerstown, Md. : 1997). 35: 400-8. PMID 22576345 DOI: 10.1097/CJI.0b013e31825898c5  0.44
2012 Yao X, Ahmadzadeh M, Lu YC, Liewehr DJ, Dudley ME, Liu F, Schrump DS, Steinberg SM, Rosenberg SA, Robbins PF. Levels of peripheral CD4(+)FoxP3(+) regulatory T cells are negatively associated with clinical response to adoptive immunotherapy of human cancer. Blood. 119: 5688-96. PMID 22555974 DOI: 10.1182/blood-2011-10-386482  0.44
2012 Yang S, Karne NK, Goff SL, Black MA, Xu H, Bischof D, Cornetta K, Rosenberg SA, Morgan RA, Feldman SA. A simple and effective method to generate lentiviral vectors for ex vivo gene delivery to mature human peripheral blood lymphocytes. Human Gene Therapy Methods. 23: 73-83. PMID 22515320 DOI: 10.1089/hgtb.2011.199  0.44
2012 Bergamaschi C, Bear J, Rosati M, Beach RK, Alicea C, Sowder R, Chertova E, Rosenberg SA, Felber BK, Pavlakis GN. Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum. Blood. 120: e1-8. PMID 22496150 DOI: 10.1182/blood-2011-10-384362  0.44
2012 Somerville RP, Devillier L, Parkhurst MR, Rosenberg SA, Dudley ME. Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactor. Journal of Translational Medicine. 10: 69. PMID 22475724 DOI: 10.1186/1479-5876-10-69  0.44
2012 Rosenberg SA. Raising the bar: the curative potential of human cancer immunotherapy. Science Translational Medicine. 4: 127ps8. PMID 22461638 DOI: 10.1126/scitranslmed.3003634  0.44
2012 Restifo NP, Dudley ME, Rosenberg SA. Adoptive immunotherapy for cancer: harnessing the T cell response. Nature Reviews. Immunology. 12: 269-81. PMID 22437939 DOI: 10.1038/nri3191  0.44
2012 Jin J, Sabatino M, Somerville R, Wilson JR, Dudley ME, Stroncek DF, Rosenberg SA. Simplified method of the growth of human tumor infiltrating lymphocytes in gas-permeable flasks to numbers needed for patient treatment. Journal of Immunotherapy (Hagerstown, Md. : 1997). 35: 283-92. PMID 22421946 DOI: 10.1097/CJI.0b013e31824e801f  0.44
2012 Stroncek DF, Berger C, Cheever MA, Childs RW, Dudley ME, Flynn P, Gattinoni L, Heath JR, Kalos M, Marincola FM, Miller JS, Mostoslavsky G, Powell DJ, Rao M, Restifo NP, ... Rosenberg SA, et al. New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer. Journal of Translational Medicine. 10: 48. PMID 22420641 DOI: 10.1186/1479-5876-10-48  0.44
2012 Lai JP, Robbins PF, Raffeld M, Aung PP, Tsokos M, Rosenberg SA, Miettinen MM, Lee CC. NY-ESO-1 expression in synovial sarcoma and other mesenchymal tumors: significance for NY-ESO-1-based targeted therapy and differential diagnosis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 25: 854-8. PMID 22388761 DOI: 10.1038/modpathol.2012.31  0.44
2012 Bear AS, Morgan RA, Cornetta K, June CH, Binder-Scholl G, Dudley ME, Feldman SA, Rosenberg SA, Shurtleff SA, Rooney CM, Heslop HE, Dotti G. Replication-competent retroviruses in gene-modified T cells used in clinical trials: is it time to revise the testing requirements? Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 246-9. PMID 22297819 DOI: 10.1038/mt.2011.288  0.44
2012 Chinnasamy D, Yu Z, Kerkar SP, Zhang L, Morgan RA, Restifo NP, Rosenberg SA. Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 1672-83. PMID 22291136 DOI: 10.1158/1078-0432.CCR-11-3050  0.44
2012 Prieto PA, Yang JC, Sherry RM, Hughes MS, Kammula US, White DE, Levy CL, Rosenberg SA, Phan GQ. CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2039-47. PMID 22271879 DOI: 10.1158/1078-0432.CCR-11-1823  0.44
2012 Kochenderfer JN, Dudley ME, Feldman SA, Wilson WH, Spaner DE, Maric I, Stetler-Stevenson M, Phan GQ, Hughes MS, Sherry RM, Yang JC, Kammula US, Devillier L, Carpenter R, Nathan DA, ... ... Rosenberg SA, et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood. 119: 2709-20. PMID 22160384 DOI: 10.1182/blood-2011-10-384388  0.44
2012 Kvistborg P, Shu CJ, Heemskerk B, Fankhauser M, Thrue CA, Toebes M, Van Rooij N, Linnemann C, Van Buuren MM, Urbanus JHM, Beltman JB, Straten P, Li YF, Robbins PF, Besser MJ, ... ... Rosenberg SA, et al. TIL therapy broadens the tumor-reactive CD8+ T cell compartment in melanoma patients Oncoimmunology. 1: 409-418. DOI: 10.4161/onci.18851  0.44
2011 Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DN, Feldman SA, Davis JL, Morgan RA, Merino MJ, Sherry RM, Hughes MS, Kammula US, Phan GQ, Lim RM, Wank SA, ... ... Rosenberg SA, et al. T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 620-626. PMID 28160822 DOI: 10.1038/mt.2010.272  0.56
2011 Kochenderfer JN, Rosenberg SA. Chimeric antigen receptor-modified T cells in CLL. The New England Journal of Medicine. 365: 1937-8; author reply. PMID 22087695 DOI: 10.1056/NEJMc1111004#SA2  0.44
2011 Kerkar SP, Goldszmid RS, Muranski P, Chinnasamy D, Yu Z, Reger RN, Leonardi AJ, Morgan RA, Wang E, Marincola FM, Trinchieri G, Rosenberg SA, Restifo NP. IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors. The Journal of Clinical Investigation. 121: 4746-57. PMID 22056381 DOI: 10.1172/JCI58814  0.44
2011 Rosenberg SA, Kochenderfer JN. Personalized cell transfer immunotherapy for B-cell malignancies and solid cancers. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1928-30. PMID 22051601 DOI: 10.1038/mt.2011.223  0.44
2011 Friedman KM, Devillier LE, Feldman SA, Rosenberg SA, Dudley ME. Augmented lymphocyte expansion from solid tumors with engineered cells for costimulatory enhancement. Journal of Immunotherapy (Hagerstown, Md. : 1997). 34: 651-61. PMID 21989413 DOI: 10.1097/CJI.0b013e31823284c3  0.44
2011 Turcotte S, Rosenberg SA. Immunotherapy for metastatic solid cancers. Advances in Surgery. 45: 341-60. PMID 21954698 DOI: 10.1016/j.yasu.2011.04.003  0.44
2011 Prickett TD, Wei X, Cardenas-Navia I, Teer JK, Lin JC, Walia V, Gartner J, Jiang J, Cherukuri PF, Molinolo A, Davies MA, Gershenwald JE, Stemke-Hale K, Rosenberg SA, Margulies EH, et al. Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nature Genetics. 43: 1119-26. PMID 21946352 DOI: 10.1038/ng.950  0.44
2011 Solomon DA, Kim T, Diaz-Martinez LA, Fair J, Elkahloun AG, Harris BT, Toretsky JA, Rosenberg SA, Shukla N, Ladanyi M, Samuels Y, James CD, Yu H, Kim JS, Waldman T. Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science (New York, N.Y.). 333: 1039-43. PMID 21852505 DOI: 10.1126/science.1203619  0.44
2011 Parkhurst MR, Riley JP, Dudley ME, Rosenberg SA. Adoptive transfer of autologous natural killer cells leads to high levels of circulating natural killer cells but does not mediate tumor regression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 6287-97. PMID 21844012 DOI: 10.1158/1078-0432.CCR-11-1347  0.44
2011 Yang S, Liu F, Wang QJ, Rosenberg SA, Morgan RA. The shedding of CD62L (L-selectin) regulates the acquisition of lytic activity in human tumor reactive T lymphocytes. Plos One. 6: e22560. PMID 21829468 DOI: 10.1371/journal.pone.0022560  0.44
2011 Rosenberg SA. Cell transfer immunotherapy for metastatic solid cancer--what clinicians need to know. Nature Reviews. Clinical Oncology. 8: 577-85. PMID 21808266 DOI: 10.1038/nrclinonc.2011.116  0.44
2011 Klebanoff CA, Gattinoni L, Palmer DC, Muranski P, Ji Y, Hinrichs CS, Borman ZA, Kerkar SP, Scott CD, Finkelstein SE, Rosenberg SA, Restifo NP. Determinants of successful CD8+ T-cell adoptive immunotherapy for large established tumors in mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5343-52. PMID 21737507 DOI: 10.1158/1078-0432.CCR-11-0503  0.44
2011 Dalet A, Robbins PF, Stroobant V, Vigneron N, Li YF, El-Gamil M, Hanada K, Yang JC, Rosenberg SA, Van den Eynde BJ. An antigenic peptide produced by reverse splicing and double asparagine deamidation. Proceedings of the National Academy of Sciences of the United States of America. 108: E323-31. PMID 21670269 DOI: 10.1073/pnas.1101892108  0.44
2011 Park TS, Rosenberg SA, Morgan RA. Treating cancer with genetically engineered T cells. Trends in Biotechnology. 29: 550-7. PMID 21663987 DOI: 10.1016/j.tibtech.2011.04.009  0.44
2011 Schwartzentruber DJ, Lawson DH, Richards JM, Conry RM, Miller DM, Treisman J, Gailani F, Riley L, Conlon K, Pockaj B, Kendra KL, White RL, Gonzalez R, Kuzel TM, Curti B, ... ... Rosenberg SA, et al. gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. The New England Journal of Medicine. 364: 2119-27. PMID 21631324 DOI: 10.1056/NEJMoa1012863  0.44
2011 Wei X, Moncada-Pazos A, Cal S, Soria-Valles C, Gartner J, Rudloff U, Lin JC, Rosenberg SA, López-Otín C, Samuels Y. Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma. Human Mutation. 32: E2148-75. PMID 21618342 DOI: 10.1002/humu.21477  0.44
2011 Ertl HC, Zaia J, Rosenberg SA, June CH, Dotti G, Kahn J, Cooper LJ, Corrigan-Curay J, Strome SE. Considerations for the clinical application of chimeric antigen receptor T cells: observations from a recombinant DNA Advisory Committee Symposium held June 15, 2010. Cancer Research. 71: 3175-81. PMID 21531763 DOI: 10.1158/0008-5472.CAN-10-4035  0.44
2011 Wei X, Walia V, Lin JC, Teer JK, Prickett TD, Gartner J, Davis S, Stemke-Hale K, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Samuels Y. Exome sequencing identifies GRIN2A as frequently mutated in melanoma. Nature Genetics. 43: 442-6. PMID 21499247 DOI: 10.1038/ng.810  0.44
2011 Huang J, Wang QJ, Yang S, Li YF, El-Gamil M, Rosenberg SA, Robbins PF. Irradiation enhances human T-cell function by upregulating CD70 expression on antigen-presenting cells in vitro. Journal of Immunotherapy (Hagerstown, Md. : 1997). 34: 327-35. PMID 21499130 DOI: 10.1097/CJI.0b013e318216983d  0.44
2011 Langan RC, Prieto PA, Sherry RM, Zlott D, Wunderlich J, Csako G, Costello R, White DE, Rosenberg SA, Yang JC. Assessment of ovarian function after preparative chemotherapy and total body radiation for adoptive cell therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 34: 397-402. PMID 21499128 DOI: 10.1097/CJI.0b013e3182187508  0.44
2011 Kerkar SP, Sanchez-Perez L, Yang S, Borman ZA, Muranski P, Ji Y, Chinnasamy D, Kaiser AD, Hinrichs CS, Klebanoff CA, Scott CD, Gattinoni L, Morgan RA, Rosenberg SA, Restifo NP. Genetic engineering of murine CD8+ and CD4+ T cells for preclinical adoptive immunotherapy studies. Journal of Immunotherapy (Hagerstown, Md. : 1997). 34: 343-52. PMID 21499127 DOI: 10.1097/CJI.0b013e3182187600  0.44
2011 Rosenberg SA, Yang JC, Sherry RM, Kammula US, Hughes MS, Phan GQ, Citrin DE, Restifo NP, Robbins PF, Wunderlich JR, Morton KE, Laurencot CM, Steinberg SM, White DE, Dudley ME. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4550-7. PMID 21498393 DOI: 10.1158/1078-0432.CCR-11-0116  0.44
2011 Lonser RR, Song DK, Klapper J, Hagan M, Auh S, Kerr PB, Citrin DE, Heiss JD, Camphausen K, Rosenberg SA. Surgical management of melanoma brain metastases in patients treated with immunotherapy. Journal of Neurosurgery. 115: 30-6. PMID 21476810 DOI: 10.3171/2011.3.JNS091107  0.44
2011 Kohn DB, Dotti G, Brentjens R, Savoldo B, Jensen M, Cooper LJ, June CH, Rosenberg S, Sadelain M, Heslop HE. CARs on track in the clinic. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 432-8. PMID 21358705 DOI: 10.1038/mt.2011.1  0.44
2011 Yang S, Gattinoni L, Luca G, Liu F, Ji Y, Yu Z, Restifo NP, Rosenberg SA, Morgan RA. In vitro generated anti-tumor T lymphocytes exhibit distinct subsets mimicking in vivo antigen-experienced cells. Cancer Immunology, Immunotherapy : Cii. 60: 739-49. PMID 21305379 DOI: 10.1007/s00262-011-0977-7  0.44
2011 Zhang L, Kerkar SP, Yu Z, Zheng Z, Yang S, Restifo NP, Rosenberg SA, Morgan RA. Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 751-9. PMID 21285960 DOI: 10.1038/mt.2010.313  0.44
2011 Robbins PF, Morgan RA, Feldman SA, Yang JC, Sherry RM, Dudley ME, Wunderlich JR, Nahvi AV, Helman LJ, Mackall CL, Kammula US, Hughes MS, Restifo NP, Raffeld M, Lee CC, ... ... Rosenberg SA, et al. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 917-24. PMID 21282551 DOI: 10.1200/JCO.2010.32.2537  0.44
2011 Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DA, Feldman SA, Davis JL, Morgan RA, Merino MJ, Sherry RM, Hughes MS, Kammula US, Phan GQ, Lim RM, Wank SA, ... ... Rosenberg SA, et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 620-6. PMID 21157437 DOI: 10.1038/mt.2010.272  0.44
2011 Chinnasamy N, Wargo JA, Yu Z, Rao M, Frankel TL, Riley JP, Hong JJ, Parkhurst MR, Feldman SA, Schrump DS, Restifo NP, Robbins PF, Rosenberg SA, Morgan RA. A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer. Journal of Immunology (Baltimore, Md. : 1950). 186: 685-96. PMID 21149604 DOI: 10.4049/jimmunol.1001775  0.44
2011 Hinrichs CS, Borman ZA, Gattinoni L, Yu Z, Burns WR, Huang J, Klebanoff CA, Johnson LA, Kerkar SP, Yang S, Muranski P, Palmer DC, Scott CD, Morgan RA, Robbins PF, ... Rosenberg SA, et al. Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy. Blood. 117: 808-14. PMID 20971955 DOI: 10.1182/blood-2010-05-286286  0.44
2011 Feldman SA, Goff SL, Xu H, Black MA, Kochenderfer JN, Johnson LA, Yang JC, Wang Q, Parkhurst MR, Cross S, Morgan RA, Cornetta K, Rosenberg SA. Rapid production of clinical-grade gammaretroviral vectors in expanded surface roller bottles using a "modified" step-filtration process for clearance of packaging cells. Human Gene Therapy. 22: 107-15. PMID 20662590 DOI: 10.1089/hum.2010.064  0.44
2011 Ertl HCJ, Zaia J, Rosenberg SA, June CH, Dotti G, Kahn J. Considerations for the clinical application of chimeric antigen receptor T cells: Observations from a Recombinant DNA Advisory Committee symposium held June 15, 2010 (Cancer Research (2011) 71, (3175-3181)) Cancer Research. 71: 4325. DOI: 10.1158/0008-5472.CAN-11-1396  0.44
2010 Davis JL, Theoret MR, Zheng Z, Lamers CH, Rosenberg SA, Morgan RA. Development of human anti-murine T-cell receptor antibodies in both responding and nonresponding patients enrolled in TCR gene therapy trials. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5852-61. PMID 21138872 DOI: 10.1158/1078-0432.CCR-10-1280  0.44
2010 Wei X, Prickett TD, Viloria CG, Molinolo A, Lin JC, Cardenas-Navia I, Cruz P, Rosenberg SA, Davies MA, Gershenwald JE, López-Otín C, Samuels Y. Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Molecular Cancer Research : McR. 8: 1513-25. PMID 21047771 DOI: 10.1158/1541-7786.MCR-10-0262  0.44
2010 Chinnasamy D, Yu Z, Theoret MR, Zhao Y, Shrimali RK, Morgan RA, Feldman SA, Restifo NP, Rosenberg SA. Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice. The Journal of Clinical Investigation. 120: 3953-68. PMID 20978347 DOI: 10.1172/JCI43490  0.44
2010 Inozume T, Hanada K, Wang QJ, Ahmadzadeh M, Wunderlich JR, Rosenberg SA, Yang JC. Selection of CD8+PD-1+ lymphocytes in fresh human melanomas enriches for tumor-reactive T cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 956-64. PMID 20948441 DOI: 10.1097/CJI.0b013e3181fad2b0  0.44
2010 Rosenberg SA. Of mice, not men: no evidence for graft-versus-host disease in humans receiving T-cell receptor-transduced autologous T cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1744-5. PMID 20885433 DOI: 10.1038/mt.2010.195  0.44
2010 Goff SL, Smith FO, Klapper JA, Sherry R, Wunderlich JR, Steinberg SM, White D, Rosenberg SA, Dudley ME, Yang JC. Tumor infiltrating lymphocyte therapy for metastatic melanoma: analysis of tumors resected for TIL. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 840-7. PMID 20842052 DOI: 10.1097/CJI.0b013e3181f05b91  0.44
2010 Frankel TL, Burns W, Riley J, Morgan RA, Davis JL, Hanada K, Quezado M, Rosenberg SA, Royal RE. Identification and characterization of a tumor infiltrating CD56(+)/CD16 (-) NK cell subset with specificity for pancreatic and prostate cancer cell lines. Cancer Immunology, Immunotherapy : Cii. 59: 1757-69. PMID 20734041 DOI: 10.1007/s00262-010-0897-y  0.44
2010 Hong JJ, Rosenberg SA, Dudley ME, Yang JC, White DE, Butman JA, Sherry RM. Successful treatment of melanoma brain metastases with adoptive cell therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4892-8. PMID 20719934 DOI: 10.1158/1078-0432.CCR-10-1507  0.44
2010 Morgan RA, Dudley ME, Rosenberg SA. Adoptive cell therapy: genetic modification to redirect effector cell specificity. Cancer Journal (Sudbury, Mass.). 16: 336-41. PMID 20693844 DOI: 10.1097/PPO.0b013e3181eb3879  0.44
2010 Kochenderfer JN, Wilson WH, Janik JE, Dudley ME, Stetler-Stevenson M, Feldman SA, Maric I, Raffeld M, Nathan DA, Lanier BJ, Morgan RA, Rosenberg SA. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood. 116: 4099-102. PMID 20668228 DOI: 10.1182/blood-2010-04-281931  0.44
2010 Dudley ME, Gross CA, Langhan MM, Garcia MR, Sherry RM, Yang JC, Phan GQ, Kammula US, Hughes MS, Citrin DE, Restifo NP, Wunderlich JR, Prieto PA, Hong JJ, Langan RC, ... ... Rosenberg SA, et al. CD8+ enriched "young" tumor infiltrating lymphocytes can mediate regression of metastatic melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 6122-31. PMID 20668005 DOI: 10.1158/1078-0432.CCR-10-1297  0.44
2010 Kerkar SP, Muranski P, Kaiser A, Boni A, Sanchez-Perez L, Yu Z, Palmer DC, Reger RN, Borman ZA, Zhang L, Morgan RA, Gattinoni L, Rosenberg SA, Trinchieri G, Restifo NP. Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts. Cancer Research. 70: 6725-34. PMID 20647327 DOI: 10.1158/0008-5472.CAN-10-0735  0.44
2010 Kochenderfer JN, Yu Z, Frasheri D, Restifo NP, Rosenberg SA. Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells. Blood. 116: 3875-86. PMID 20631379 DOI: 10.1182/blood-2010-01-265041  0.44
2010 Shrimali RK, Yu Z, Theoret MR, Chinnasamy D, Restifo NP, Rosenberg SA. Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer. Cancer Research. 70: 6171-80. PMID 20631075 DOI: 10.1158/0008-5472.CAN-10-0153  0.44
2010 Goff SL, Johnson LA, Black MA, Xu H, Zheng Z, Cohen CJ, Morgan RA, Rosenberg SA, Feldman SA. Enhanced receptor expression and in vitro effector function of a murine-human hybrid MART-1-reactive T cell receptor following a rapid expansion. Cancer Immunology, Immunotherapy : Cii. 59: 1551-60. PMID 20628878 DOI: 10.1007/s00262-010-0882-5  0.44
2010 Klapper JA, Davis JL, Ripley RT, Smith FO, Nguyen DM, Kwong KF, Mercedes L, Kemp CD, Mathur A, White DE, Dudley ME, Wunderlich JR, Rosenberg SA, Schrump DS. Thoracic metastasectomy for adoptive immunotherapy of melanoma: a single-institution experience. The Journal of Thoracic and Cardiovascular Surgery. 140: 1276-82. PMID 20584535 DOI: 10.1016/j.jtcvs.2010.05.020  0.44
2010 Rosenberg SA, Yang JC, Kammula US, Hughes MS, Restifo NP, Schwarz SL, Morton KE, Laurencot CM, Sherry RM. Different adjuvanticity of incomplete freund's adjuvant derived from beef or vegetable components in melanoma patients immunized with a peptide vaccine. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 626-9. PMID 20551834 DOI: 10.1097/CJI.0b013e3181dac9de  0.44
2010 Yang S, Dudley ME, Rosenberg SA, Morgan RA. A simplified method for the clinical-scale generation of central memory-like CD8+ T cells after transduction with lentiviral vectors encoding antitumor antigen T-cell receptors. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 648-58. PMID 20551831 DOI: 10.1097/CJI.0b013e3181e311cb  0.44
2010 Prieto PA, Durflinger KH, Wunderlich JR, Rosenberg SA, Dudley ME. Enrichment of CD8+ cells from melanoma tumor-infiltrating lymphocyte cultures reveals tumor reactivity for use in adoptive cell therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 547-56. PMID 20463593 DOI: 10.1097/CJI.0b013e3181d367bd  0.44
2010 Davis JL, Ripley RT, Frankel TL, Maric I, Lozier JN, Rosenberg SA. Paraneoplastic granulocytosis in metastatic melanoma. Melanoma Research. 20: 326-9. PMID 20440226 DOI: 10.1097/CMR.0b013e328339da1e  0.44
2010 Frankel TL, Burns WR, Peng PD, Yu Z, Chinnasamy D, Wargo JA, Zheng Z, Restifo NP, Rosenberg SA, Morgan RA. Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase. Journal of Immunology (Baltimore, Md. : 1950). 184: 5988-98. PMID 20427771 DOI: 10.4049/jimmunol.1000189  0.44
2010 Cárdenas-Navia LI, Cruz P, Lin JC, Rosenberg SA, Samuels Y. Novel somatic mutations in heterotrimeric G proteins in melanoma. Cancer Biology & Therapy. 10: 33-7. PMID 20424519  0.44
2010 Burns WR, Zhao Y, Frankel TL, Hinrichs CS, Zheng Z, Xu H, Feldman SA, Ferrone S, Rosenberg SA, Morgan RA. A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas. Cancer Research. 70: 3027-33. PMID 20395199 DOI: 10.1158/0008-5472.CAN-09-2824  0.44
2010 Morgan RA, Yang JC, Kitano M, Dudley ME, Laurencot CM, Rosenberg SA. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 843-51. PMID 20179677 DOI: 10.1038/mt.2010.24  0.44
2010 Wrzesinski C, Paulos CM, Kaiser A, Muranski P, Palmer DC, Gattinoni L, Yu Z, Rosenberg SA, Restifo NP. Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 1-7. PMID 19952961 DOI: 10.1097/CJI.0b013e3181b88ffc  0.44
2010 Ripley RT, Davis JL, Klapper JA, Mathur A, Kammula U, Royal RE, Yang JC, Sherry RM, Hughes MS, Libutti SK, White DE, Steinberg SM, Dudley ME, Rosenberg SA, Avital I. Liver resection for metastatic melanoma with postoperative tumor-infiltrating lymphocyte therapy. Annals of Surgical Oncology. 17: 163-70. PMID 19777192 DOI: 10.1245/s10434-009-0677-0  0.44
2009 Kerkar SP, Kemp CD, Duffy A, Kammula US, Schrump DS, Kwong KF, Quezado M, Goldspiel BR, Venkatesan A, Berger A, Walker M, Toomey MA, Steinberg SM, Giaccone G, Rosenberg SA, et al. The GYMSSA trial: a prospective randomized trial comparing gastrectomy, metastasectomy plus systemic therapy versus systemic therapy alone. Trials. 10: 121. PMID 20030854 DOI: 10.1186/1745-6215-10-121  0.44
2009 Zhao Y, Wang QJ, Yang S, Kochenderfer JN, Zheng Z, Zhong X, Sadelain M, Eshhar Z, Rosenberg SA, Morgan RA. A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity. Journal of Immunology (Baltimore, Md. : 1950). 183: 5563-74. PMID 19843940 DOI: 10.4049/jimmunol.0900447  0.44
2009 Hinrichs CS, Borman ZA, Cassard L, Gattinoni L, Spolski R, Yu Z, Sanchez-Perez L, Muranski P, Kern SJ, Logun C, Palmer DC, Ji Y, Reger RN, Leonard WJ, Danner RL, ... Rosenberg SA, et al. Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America. 106: 17469-74. PMID 19805141 DOI: 10.1073/pnas.0907448106  0.44
2009 Smith FO, Klapper JA, Wunderlich JR, Rosenberg SA, Dudley ME. Impact of a recombinant fowlpox vaccine on the efficacy of adoptive cell therapy with tumor infiltrating lymphocytes in a patient with metastatic melanoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 32: 870-4. PMID 19752747 DOI: 10.1097/CJI.0b013e3181b36b69  0.44
2009 Goff SL, Robbins PF, El-Gamil M, Rosenberg SA. No correlation between clinical response to CTLA-4 blockade and presence of NY-ESO-1 antibody in patients with metastatic melanoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 32: 884-5. PMID 19752745 DOI: 10.1097/CJI.0b013e3181affbf0  0.44
2009 Prickett TD, Agrawal NS, Wei X, Yates KE, Lin JC, Wunderlich JR, Cronin JC, Cruz P, Rosenberg SA, Samuels Y. Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nature Genetics. 41: 1127-32. PMID 19718025 DOI: 10.1038/ng.438  0.44
2009 Burns WR, Zheng Z, Rosenberg SA, Morgan RA. Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation. Blood. 114: 2888-99. PMID 19589923 DOI: 10.1182/blood-2009-01-199216  0.44
2009 Kochenderfer JN, Feldman SA, Zhao Y, Xu H, Black MA, Morgan RA, Wilson WH, Rosenberg SA. Construction and preclinical evaluation of an anti-CD19 chimeric antigen receptor. Journal of Immunotherapy (Hagerstown, Md. : 1997). 32: 689-702. PMID 19561539 DOI: 10.1097/CJI.0b013e3181ac6138  0.44
2009 Peng PD, Cohen CJ, Yang S, Hsu C, Jones S, Zhao Y, Zheng Z, Rosenberg SA, Morgan RA. Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity. Gene Therapy. 16: 1042-9. PMID 19494842 DOI: 10.1038/gt.2009.54  0.44
2009 Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS, Kammula US, Royal RE, Sherry RM, Wunderlich JR, Lee CC, Restifo NP, Schwarz SL, Cogdill AP, Bishop RJ, ... ... Rosenberg SA, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood. 114: 535-46. PMID 19451549 DOI: 10.1182/blood-2009-03-211714  0.44
2009 Ahmadzadeh M, Johnson LA, Heemskerk B, Wunderlich JR, Dudley ME, White DE, Rosenberg SA. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood. 114: 1537-44. PMID 19423728 DOI: 10.1182/blood-2008-12-195792  0.44
2009 Cronin JC, Wunderlich J, Loftus SK, Prickett TD, Wei X, Ridd K, Vemula S, Burrell AS, Agrawal NS, Lin JC, Banister CE, Buckhaults P, Rosenberg SA, Bastian BC, Pavan WJ, et al. Frequent mutations in the MITF pathway in melanoma. Pigment Cell & Melanoma Research. 22: 435-44. PMID 19422606 DOI: 10.1111/j.1755-148X.2009.00578.x  0.44
2009 Yeh S, Karne NK, Kerkar SP, Heller CK, Palmer DC, Johnson LA, Li Z, Bishop RJ, Wong WT, Sherry RM, Yang JC, Dudley ME, Restifo NP, Rosenberg SA, Nussenblatt RB. Ocular and systemic autoimmunity after successful tumor-infiltrating lymphocyte immunotherapy for recurrent, metastatic melanoma. Ophthalmology. 116: 981-989.e1. PMID 19410956 DOI: 10.1016/j.ophtha.2008.12.004  0.44
2009 Klapper JA, Thomasian AA, Smith DM, Gorgas GC, Wunderlich JR, Smith FO, Hampson BS, Rosenberg SA, Dudley ME. Single-pass, closed-system rapid expansion of lymphocyte cultures for adoptive cell therapy. Journal of Immunological Methods. 345: 90-9. PMID 19389403 DOI: 10.1016/j.jim.2009.04.009  0.44
2009 Palavalli LH, Prickett TD, Wunderlich JR, Wei X, Burrell AS, Porter-Gill P, Davis S, Wang C, Cronin JC, Agrawal NS, Lin JC, Westbroek W, Hoogstraten-Miller S, Molinolo AA, Fetsch P, ... ... Rosenberg SA, et al. Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nature Genetics. 41: 518-20. PMID 19330028 DOI: 10.1038/ng.340  0.44
2009 Rosenberg SA, Dudley ME. Adoptive cell therapy for the treatment of patients with metastatic melanoma. Current Opinion in Immunology. 21: 233-40. PMID 19304471 DOI: 10.1016/j.coi.2009.03.002  0.44
2009 Jones S, Peng PD, Yang S, Hsu C, Cohen CJ, Zhao Y, Abad J, Zheng Z, Rosenberg SA, Morgan RA. Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes. Human Gene Therapy. 20: 630-40. PMID 19265475 DOI: 10.1089/hum.2008.048  0.44
2009 Parkhurst MR, Joo J, Riley JP, Yu Z, Li Y, Robbins PF, Rosenberg SA. Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 169-80. PMID 19118044 DOI: 10.1158/1078-0432.CCR-08-1638  0.56
2009 Wargo JA, Robbins PF, Li Y, Zhao Y, El-Gamil M, Caragacianu D, Zheng Z, Hong JA, Downey S, Schrump DS, Rosenberg SA, Morgan RA. Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression. Cancer Immunology, Immunotherapy : Cii. 58: 383-94. PMID 18677478 DOI: 10.1007/s00262-008-0562-x  0.44
2008 Theoret MR, Cohen CJ, Nahvi AV, Ngo LT, Suri KB, Powell DJ, Dudley ME, Morgan RA, Rosenberg SA. Relationship of p53 overexpression on cancers and recognition by anti-p53 T cell receptor-transduced T cells. Human Gene Therapy. 19: 1219-32. PMID 19848582 DOI: 10.1089/hgt.2008.083  0.44
2008 Solomon DA, Kim JS, Cronin JC, Sibenaller Z, Ryken T, Rosenberg SA, Ressom H, Jean W, Bigner D, Yan H, Samuels Y, Waldman T. Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma. Cancer Research. 68: 10300-6. PMID 19074898 DOI: 10.1158/0008-5472.CAN-08-3272  0.44
2008 Yang S, Rosenberg SA, Morgan RA. Clinical-scale lentiviral vector transduction of PBL for TCR gene therapy and potential for expression in less-differentiated cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). 31: 830-9. PMID 18833004 DOI: 10.1097/CJI.0b013e31818817c5  0.44
2008 Ahmadzadeh M, Felipe-Silva A, Heemskerk B, Powell DJ, Wunderlich JR, Merino MJ, Rosenberg SA. FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions. Blood. 112: 4953-60. PMID 18820132 DOI: 10.1182/blood-2008-06-163048  0.44
2008 Dudley ME, Yang JC, Sherry R, Hughes MS, Royal R, Kammula U, Robbins PF, Huang J, Citrin DE, Leitman SF, Wunderlich J, Restifo NP, Thomasian A, Downey SG, Smith FO, ... ... Rosenberg SA, et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 5233-9. PMID 18809613 DOI: 10.1200/JCO.2008.16.5449  0.44
2008 Boni A, Muranski P, Cassard L, Wrzesinski C, Paulos CM, Palmer DC, Gattinoni L, Hinrichs CS, Chan CC, Rosenberg SA, Restifo NP. Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers. Blood. 112: 4746-54. PMID 18799724 DOI: 10.1182/blood-2008-07-169797  0.44
2008 Tran KQ, Zhou J, Durflinger KH, Langhan MM, Shelton TE, Wunderlich JR, Robbins PF, Rosenberg SA, Dudley ME. Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 31: 742-51. PMID 18779745 DOI: 10.1097/CJI.0b013e31818403d5  0.44
2008 Rosenberg SA, Dudley ME, Restifo NP. Cancer immunotherapy. The New England Journal of Medicine. 359: 1072. PMID 18768956 DOI: 10.1056/NEJMc081511  0.44
2008 Smith FO, Downey SG, Klapper JA, Yang JC, Sherry RM, Royal RE, Kammula US, Hughes MS, Restifo NP, Levy CL, White DE, Steinberg SM, Rosenberg SA. Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5610-8. PMID 18765555 DOI: 10.1158/1078-0432.CCR-08-0116  0.44
2008 Rosenberg SA. Overcoming obstacles to the effective immunotherapy of human cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 12643-4. PMID 18753635 DOI: 10.1073/pnas.0806877105  0.44
2008 Palmer DC, Chan CC, Gattinoni L, Wrzesinski C, Paulos CM, Hinrichs CS, Powell DJ, Klebanoff CA, Finkelstein SE, Fariss RN, Yu Z, Nussenblatt RB, Rosenberg SA, Restifo NP. Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 105: 8061-6. PMID 18523011 DOI: 10.1073/pnas.0710929105  0.44
2008 Yang S, Cohen CJ, Peng PD, Zhao Y, Cassard L, Yu Z, Zheng Z, Jones S, Restifo NP, Rosenberg SA, Morgan RA. Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition. Gene Therapy. 15: 1411-23. PMID 18496571 DOI: 10.1038/gt.2008.90  0.44
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2007 Rosenberg SA. Interleukin 2 for patients with renal cancer. Nature Clinical Practice. Oncology. 4: 497. PMID 17728709 DOI: 10.1038/ncponc0926  0.44
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2005 Restifo NP, Rosenberg SA. Use of standard criteria for assessment of cancer vaccines. The Lancet. Oncology. 6: 3-4. PMID 15629270 DOI: 10.1016/S1470-2045(04)01693-6  0.44
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2004 Robinson MR, Chan CC, Yang JC, Rubin BI, Gracia GJ, Sen HN, Csaky KG, Rosenberg SA. Cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma: a new cause of uveitis. Journal of Immunotherapy (Hagerstown, Md. : 1997). 27: 478-9. PMID 15534492  0.44
2004 Khong HT, Yang JC, Topalian SL, Sherry RM, Mavroukakis SA, White DE, Rosenberg SA. Immunization of HLA-A*0201 and/or HLA-DPbeta1*04 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen. Journal of Immunotherapy (Hagerstown, Md. : 1997). 27: 472-7. PMID 15534491  0.44
2004 Rosenberg SA, Dudley ME. Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 101: 14639-45. PMID 15381769 DOI: 10.1073/pnas.0405730101  0.44
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2004 Parkhurst MR, Riley JP, Robbins PF, Rosenberg SA. Induction of CD4+ Th1 lymphocytes that recognize known and novel class II MHC restricted epitopes from the melanoma antigen gp100 by stimulation with recombinant protein. Journal of Immunotherapy (Hagerstown, Md. : 1997). 27: 79-91. PMID 14770079  0.44
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2003 Morgan RA, Dudley ME, Yu YY, Zheng Z, Robbins PF, Theoret MR, Wunderlich JR, Hughes MS, Restifo NP, Rosenberg SA. High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens. Journal of Immunology (Baltimore, Md. : 1950). 171: 3287-95. PMID 12960359  0.44
2003 Dudley ME, Rosenberg SA. Adoptive-cell-transfer therapy for the treatment of patients with cancer. Nature Reviews. Cancer. 3: 666-75. PMID 12951585 DOI: 10.1038/nrc1167  0.44
2003 Nagorsen D, Panelli M, Dudley ME, Finkelstein SE, Rosenberg SA, Marincola FM. Biased epitope selection by recombinant vaccinia-virus (rVV)-infected mature or immature dendritic cells. Gene Therapy. 10: 1754-65. PMID 12939642 DOI: 10.1038/sj.gt.3302066  0.44
2003 Overwijk WW, Theoret MR, Finkelstein SE, Surman DR, de Jong LA, Vyth-Dreese FA, Dellemijn TA, Antony PA, Spiess PJ, Palmer DC, Heimann DM, Klebanoff CA, Yu Z, Hwang LN, Feigenbaum L, ... ... Rosenberg SA, et al. Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells. The Journal of Experimental Medicine. 198: 569-80. PMID 12925674 DOI: 10.1084/jem.20030590  0.44
2003 Phan GQ, Touloukian CE, Yang JC, Restifo NP, Sherry RM, Hwu P, Topalian SL, Schwartzentruber DJ, Seipp CA, Freezer LJ, Morton KE, Mavroukakis SA, White DE, Rosenberg SA. Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens. Journal of Immunotherapy (Hagerstown, Md. : 1997). 26: 349-56. PMID 12843797 DOI: 10.1097/00002371-200307000-00007  0.44
2003 Dudley ME, Wunderlich JR, Shelton TE, Even J, Rosenberg SA. Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. Journal of Immunotherapy (Hagerstown, Md. : 1997). 26: 332-42. PMID 12843795 DOI: 10.1097/00002371-200307000-00005  0.44
2003 Phan GQ, Yang JC, Sherry RM, Hwu P, Topalian SL, Schwartzentruber DJ, Restifo NP, Haworth LR, Seipp CA, Freezer LJ, Morton KE, Mavroukakis SA, Duray PH, Steinberg SM, Allison JP, ... ... Rosenberg SA, et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proceedings of the National Academy of Sciences of the United States of America. 100: 8372-7. PMID 12826605 DOI: 10.1073/pnas.1533209100  0.44
2003 Rosenberg SA, Yang JC, Sherry RM, Hwu P, Topalian SL, Schwartzentruber DJ, Restifo NP, Haworth LR, Seipp CA, Freezer LJ, Morton KE, Mavroukakis SA, White DE. Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen. Human Gene Therapy. 14: 709-14. PMID 12804135 DOI: 10.1089/104303403765255110  0.4
2003 Riley JP, Rosenberg SA, Parkhurst MR. Stimulation of tumor-reactive T lymphocytes using mixtures of synthetic peptides derived from tumor-associated antigens with diverse MHC binding affinities Journal of Immunological Methods. 276: 103-119. PMID 12738363 DOI: 10.1016/S0022-1759(03)00078-4  0.44
2003 Parkhurst MR, DePan C, Riley JP, Rosenberg SA, Shu S. Hybrids of dendritic cells and tumor cells generated by electrofusion simultaneously present immunodominant epitopes from multiple human tumor-associated antigens in the context of MHC class I and class II molecules Journal of Immunology. 170: 5317-5325. PMID 12734382 DOI: 10.4049/jimmunol.170.10.5317  0.44
2003 Attia P, Phan GQ, Duray PH, Rosenberg SA. Parathyroid hormone-related protein and hypercalcemia in patients with metastatic melanoma: case report and review. American Journal of Clinical Oncology. 26: 42-5. PMID 12576923 DOI: 10.1097/00000421-200302000-00009  0.44
2003 Touloukian CE, Leitner WW, Schnur RE, Robbins PF, Li Y, Southwood S, Sette A, Rosenberg SA, Restifo NP. Normal tissue depresses while tumor tissue enhances human T cell responses in vivo to a novel self/tumor melanoma antigen, OA1. Journal of Immunology (Baltimore, Md. : 1950). 170: 1579-85. PMID 12538723  0.44
2002 Robbins PF, El-Gamil M, Li YF, Zeng G, Dudley M, Rosenberg SA. Multiple HLA class II-restricted melanocyte differentiation antigens are recognized by tumor-infiltrating lymphocytes from a patient with melanoma. Journal of Immunology (Baltimore, Md. : 1950). 169: 6036-47. PMID 12421991 DOI: 10.4049/jimmunol.169.10.6036  0.56
2002 Dudley ME, Wunderlich JR, Robbins PF, Yang JC, Hwu P, Schwartzentruber DJ, Topalian SL, Sherry R, Restifo NP, Hubicki AM, Robinson MR, Raffeld M, Duray P, Seipp CA, Rogers-Freezer L, ... ... Rosenberg SA, et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science (New York, N.Y.). 298: 850-4. PMID 12242449 DOI: 10.1126/science.1076514  0.44
2002 Weinreich DM, Rosenberg SA. Response rates of patients with metastatic melanoma to high-dose intravenous interleukin-2 after prior exposure to alpha-interferon or low-dose interleukin-2. Journal of Immunotherapy (Hagerstown, Md. : 1997). 25: 185-7. PMID 12074048 DOI: 10.1097/00002371-200203000-00006  0.44
2002 Monsurrò V, Nagorsen D, Wang E, Provenzano M, Dudley ME, Rosenberg SA, Marincola FM. Functional heterogeneity of vaccine-induced CD8(+) T cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 5933-42. PMID 12023400 DOI: 10.4049/jimmunol.168.11.5933  0.44
2002 Marroquin CE, Westwood JA, Lapointe R, Mixon A, Wunderlich JR, Caron D, Rosenberg SA, Hwu P. Mobilization of dendritic cell precursors in patients with cancer by Flt3 ligand allows the generation of higher yields of cultured dendritic cells Journal of Immunotherapy. 25: 278-288. PMID 12000870 DOI: 10.1097/00002371-200205000-00011  0.44
2002 Dudley ME, Wunderlich JR, Yang JC, Hwu P, Schwartzentruber DJ, Topalian SL, Sherry RM, Marincola FM, Leitman SF, Seipp CA, Rogers-Freezer L, Morton KE, Nahvi A, Mavroukakis SA, White DE, ... Rosenberg SA, et al. A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 25: 243-51. PMID 12000866 DOI: 10.1097/00002371-200205000-00007  0.44
2002 Guirguis LM, Yang JC, White DE, Steinberg SM, Liewehr DJ, Rosenberg SA, Schwartzentruber DJ. Safety and efficacy of high-dose interleukin-2 therapy in patients with brain metastases. Journal of Immunotherapy (Hagerstown, Md. : 1997). 25: 82-7. PMID 11924913 DOI: 10.1097/00002371-200201000-00009  0.44
2002 Rosenberg SA, Tong-On P, Li Y, Riley JP, El-Gamil M, Parkhurst MR, Robbins PF. Identification of BING-4 cancer antigen translated from an alternative open reading frame of a gene in the extended MHC class II region using lymphocytes from a patient with a durable complete regression following immunotherapy. Journal of Immunology (Baltimore, Md. : 1950). 168: 2402-7. PMID 11859131 DOI: 10.4049/jimmunol.168.5.2402  0.56
2001 Rosenberg SA. Progress in the development of immunotherapy for the treatment of patients with cancer Journal of Internal Medicine. 250: 462-475. PMID 11902815 DOI: 10.1046/j.1365-2796.2001.00911.x  0.44
2001 Mocellin S, Fetsch P, Abati A, Phan GQ, Wang E, Provenzano M, Stroncek D, Rosenberg SA, Marincola FM. Laser scanning cytometry evaluation of MART-1, gp100, and HLA-A2 expression in melanoma metastases Journal of Immunotherapy. 24: 447-458. PMID 11759068 DOI: 10.1097/00002371-200111000-00002  0.44
2001 Liu K, Rosenberg SA. Transduction of an IL-2 gene into human melanoma-reactive lymphocytes results in their continued growth in the absence of exogenous IL-2 and maintenance of specific antitumor activity Journal of Immunology. 167: 6356-6365. PMID 11714800 DOI: 10.4049/jimmunol.167.11.6356  0.44
2001 Dudley ME, Wunderlich J, Nishimura MI, Yu D, Yang JC, Topalian SL, Schwartzentruber DJ, Hwu P, Marincola FM, Sherry R, Leitman SF, Rosenberg SA. Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 24: 363-73. PMID 11565838 DOI: 10.1097/00002371-200107000-00012  0.44
2001 Phan GQ, Attia P, Steinberg SM, White DE, Rosenberg SA. Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 3477-82. PMID 11481353 DOI: 10.1200/JCO.2001.19.15.3477  0.44
2001 Ohnmacht GA, Phan GQ, Mavroukakis SA, Steinberg SM, Shea YR, Witebsky FG, McIntyre LS, Goodwin RS, Muehlbauer PM, Morton KE, Rogers-Freezer LJ, Seipp CA, Rosenberg SA, Marincola FM. A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Effect of Nystatin on the Development of Oral Irritation in Patients Receiving High-Dose Intravenous Interleukin-2. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 24: 188-192. PMID 11449076 DOI: 10.1097/00002371-200103000-00014  0.44
2001 Riley JP, Rosenberg SA, Parkhurst MR. Identification of a new shared HLA-A2.1 restricted epitope from the melanoma antigen tyrosinase Journal of Immunotherapy. 24: 212-220. PMID 11394498 DOI: 10.1097/00002371-200105000-00004  0.44
2001 Rosenberg SA. Progress in human tumour immunology and immunotherapy Nature. 411: 380-384. PMID 11357146 DOI: 10.1038/35077246  0.44
2001 Monsurrò V, Nielsen MB, Perez-Diez A, Dudley ME, Wang E, Rosenberg SA, Marincola FM. Kinetics of TCR use in response to repeated epitope-specific immunization. Journal of Immunology (Baltimore, Md. : 1950). 166: 5817-25. PMID 11313426 DOI: 10.4049/jimmunol.166.9.5817  0.44
2001 Weiser TS, Guo ZS, Ohnmacht GA, Parkhurst ML, Tong-On P, Marincola FM, Fischette MR, Yu X, Chen GA, Hong JA, Stewart JH, Nguyen DM, Rosenberg SA, Schrump DS. Sequential 5-Aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1. Journal of Immunotherapy (Hagerstown, Md. : 1997). 24: 151-61. PMID 11265773 DOI: 10.1097/00002371-200103000-00010  0.44
2001 Zeng G, Wang X, Robbins PF, Rosenberg SA, Wang RF. CD4(+) T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA DP4 allele: association with NY-ESO-1 antibody production. Proceedings of the National Academy of Sciences of the United States of America. 98: 3964-9. PMID 11259659 DOI: 10.1073/pnas.061507398  0.56
2001 Bownds S, Tong-On P, Rosenberg SA, Parkhurst M. Induction of tumor-reactive cytotoxic T-lymphocytes using a peptide from NY-ESO-1 modified at the carboxy-terminus to enhance HLA-A2.1 binding affinity and stability in solution Journal of Immunotherapy. 24: 1-9. PMID 11211143 DOI: 10.1097/00002371-200101000-00001  0.44
2000 Parker LL, Do MT, Westwood JA, Wunderlich JR, Dudley ME, Rosenberg SA, Hwu P. Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer. Human Gene Therapy. 11: 2377-87. PMID 11096442 DOI: 10.1089/104303400750038480  0.44
2000 McKee MD, Clay TM, Diamond RA, Rosenberg SA, Nishimura MI. Quantitation of T-cell receptor frequencies by competitive polymerase chain reaction: dynamics of T-cell clonotype frequencies in an expanding tumor-infiltrating lymphocyte culture. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 419-29. PMID 10916751 DOI: 10.1097/00002371-200007000-00005  0.4
2000 Zeng G, Touloukian CE, Wang X, Restifo NP, Rosenberg SA, Wang RF. Identification of CD4+ T cell epitopes from NY-ESO-1 presented by HLA-DR molecules. Journal of Immunology (Baltimore, Md. : 1950). 165: 1153-9. PMID 10878395  0.44
2000 Touloukian CE, Leitner WW, Topalian SL, Li YF, Robbins PF, Rosenberg SA, Restifo NP. Identification of a MHC class II-restricted human gp100 epitope using DR4-IE transgenic mice Journal of Immunology. 164: 3535-3542. PMID 10725708  0.44
2000 Kawakami Y, Dang N, Wang X, Tupesis J, Robbins PF, Wang RF, Wunderlich JR, Yannelli JR, Rosenberg SA. Recognition of shared melanoma antigens in association with major HLA-A alleles by tumor infiltrating T lymphocytes from 123 patients with melanoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 17-27. PMID 10687134  1
1999 Kaufman HL, Rao JB, Irvine KR, Bronte V, Rosenberg SA, Restifo NP, Irivine KR. Interleukin-10 enhances the therapeutic effectiveness of a recombinant poxvirus-based vaccine in an experimental murine tumor model. Journal of Immunotherapy (Hagerstown, Md. : 1997). 22: 489-96. PMID 10570747 DOI: 10.1097/00002371-199911000-00003  0.44
1999 Wang RF, Rosenberg SA. Human tumor antigens for cancer vaccine development. Immunological Reviews. 170: 85-100. PMID 10566144 DOI: 10.1111/j.1600-065X.1999.tb01331.x  0.48
1999 Dudley ME, Nishimura MI, Holt AK, Rosenberg SA. Antitumor immunization with a minimal peptide epitope (G9-209-2M) leads to a functionally heterogeneous CTL response. Journal of Immunotherapy (Hagerstown, Md. : 1997). 22: 288-98. PMID 10404430 DOI: 10.1097/00002371-199907000-00002  0.44
1999 Wang RF, Wang X, Atwood AC, Topalian SL, Rosenberg SA. Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen. Science (New York, N.Y.). 284: 1351-4. PMID 10334988 DOI: 10.1126/SCIENCE.284.5418.1351  0.48
1999 Wang RF, Wang X, Rosenberg SA. Identification of a novel major histocompatibility complex class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4(+) T cells. The Journal of Experimental Medicine. 189: 1659-68. PMID 10330445 DOI: 10.1084/jem.189.10.1659  0.48
1999 Rosenberg SA. A new era for cancer immunotherapy based on the genes that encode cancer antigens Immunity. 10: 281-287. PMID 10204484 DOI: 10.1016/S1074-7613(00)80028-X  0.44
1999 Overwijk WW, Lee DS, Surman DR, Irvine KR, Touloukian CE, Chan CC, Carroll MW, Moss B, Rosenberg SA, Restifo NP. Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 96: 2982-7. PMID 10077623 DOI: 10.1073/pnas.96.6.2982  0.44
1999 Pieper R, Christian RE, Gonzales MI, Nishimura MI, Gupta G, Settlage RE, Shabanowitz J, Rosenberg SA, Hunt DF, Topalian SL. Biochemical identification of a mutated human melanoma antigen recognized by CD4(+) T cells. The Journal of Experimental Medicine. 189: 757-66. PMID 10049939  0.4
1999 Restifo NP, Rosenberg SA. Developing recombinant and synthetic vaccines for the treatment of melanoma Current Opinion in Oncology. 11: 50-57. PMID 9914879 DOI: 10.1097/00001622-199901000-00012  0.44
1998 Kawakami Y, Robbins PF, Wang X, Tupesis JP, Parkhurst MR, Kang X, Sakaguchi K, Appella E, Rosenberg SA. Identification of new melanoma epitopes on melanosomal proteins recognized by tumor infiltrating T lymphocytes restricted by HLA-A1, -A2, and -A3 alleles. Journal of Immunology (Baltimore, Md. : 1950). 161: 6985-92. PMID 9862734  1
1998 Rosenberg SA, Zhai Y, Yang JC, Schwartzentruber DJ, Hwu P, Marincola FM, Topalian SL, Restifo NP, Seipp CA, Einhorn JH, Roberts B, White DE. Immunizing patients with metastatic melanoma using recombinant adenoviruses encoding MART-1 or gp100 melanoma antigens. Journal of the National Cancer Institute. 90: 1894-900. PMID 9862627 DOI: 10.1093/jnci/90.24.1894  0.4
1998 Parkhurst MR, Fitzgerald EB, Southwood S, Sette A, Rosenberg SA, Kawakami Y. Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2). Cancer Research. 58: 4895-901. PMID 9809996  1
1998 Nishimura MI, Custer MC, Schwarz SL, Parker LL, Mixon A, Clay TM, Yannelli JR, Rosenberg SA. T cell-receptor V gene use by CD4+ melanoma-reactive clonal and oligoclonal T-cell lines. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 352-62. PMID 9789197 DOI: 10.1097/00002371-199809000-00003  0.44
1998 Restifo NP, Surman DR, Zheng H, Palese P, Rosenberg SA, García-Sastre A. Transfectant influenza A viruses are effective recombinant immunogens in the treatment of experimental cancer Virology. 249: 89-97. PMID 9740780 DOI: 10.1006/viro.1998.9330  0.44
1998 Surman DR, Irvine KR, Shulman EP, Allweis TM, Rosenberg SA, Restifo NP. Generation of polyclonal rabbit antisera to mouse melanoma associated antigens using gene gun immunization Journal of Immunological Methods. 214: 51-62. PMID 9692858 DOI: 10.1016/S0022-1759(98)00036-2  0.44
1998 Kawakami Y, Robbins PF, Wang RF, Parkhurst M, Kang X, Rosenberg SA. The use of melanosomal proteins in the immunotherapy of melanoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 237-46. PMID 9672845  0.44
1998 Overwijk WW, Tsung A, Irvine KR, Parkhurst MR, Goletz TJ, Tsung K, Carroll MW, Liu C, Moss B, Rosenberg SA, Restifo NP. gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand. The Journal of Experimental Medicine. 188: 277-86. PMID 9670040 DOI: 10.1084/jem.188.2.277  0.44
1998 Rosenberg SA, Yang JC, Schwartzentruber DJ, Hwu P, Marincola FM, Topalian SL, Restifo NP, Dudley ME, Schwarz SL, Spiess PJ, Wunderlich JR, Parkhurst MR, Kawakami Y, Seipp CA, Einhorn JH, et al. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nature Medicine. 4: 321-7. PMID 9500606 DOI: 10.1038/nm0398-321  0.44
1997 Kawakami Y, Rosenberg SA. Human tumor antigens recognized by T-cells. Immunologic Research. 16: 313-39. PMID 9439758 DOI: 10.1007/BF02786397  1
1997 Irvine KR, Chamberlain RS, Shulman EP, Surman DR, Rosenberg SA, Restifo NP. Enhancing efficacy of recombinant anticancer vaccines with prime/boost regimens that use two different vectors Journal of the National Cancer Institute. 89: 1595-1601. PMID 9362157  0.44
1997 Walther MM, Yang JC, Pass HI, Linehan WM, Rosenberg SA. Cytoreductive surgery before high dose interleukin-2 based therapy in patients with metastatic renal cell carcinoma Journal of Urology. 158: 1675-1678. PMID 9334576 DOI: 10.1016/S0022-5347(01)64091-6  0.44
1997 Specht JM, Wang G, Do MT, Lam JS, Royal RE, Reeves ME, Rosenberg SA, Hwu P. Dendritic cells retrovirally transduced with a model antigen gene are therapeutically effective against established pulmonary metastases Journal of Experimental Medicine. 186: 1213-1221. PMID 9334360 DOI: 10.1084/jem.186.8.1213  0.44
1997 Kim CJ, Prevette T, Cormier J, Overwijk W, Roden M, Restifo NP, Rosenberg SA, Marincola FM. Dendritic cells infected with poxviruses encoding MART-1/Melan A sensitize T lymphocytes in vitro Journal of Immunotherapy. 20: 276-286. PMID 9220317 DOI: 10.1097/00002371-199707000-00004  0.44
1997 Shilyansky J, Yang JC, Custer MC, Spiess P, Mixon A, Cole DJ, Mulé JJ, Rosenberg SA, Nishimura MI. Identification of a T-cell receptor from a therapeutic murine T-cell clone. Journal of Immunotherapy (Hagerstown, Md. : 1997). 20: 247-55. PMID 9220314 DOI: 10.1097/00002371-199707000-00001  0.44
1997 Robbins PF, El-Gamil M, Li YF, Fitzgerald EB, Kawakami Y, Rosenberg SA. The intronic region of an incompletely spliced gp100 gene transcript encodes an epitope recognized by melanoma-reactive tumor-infiltrating lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 159: 303-8. PMID 9200467  1
1997 Carroll MW, Overwijk WW, Chamberlain RS, Rosenberg SA, Moss B, Restifo NP. Highly attenuated modified vaccinia virus Ankara (MVA) as an effective recombinant vector: a murine tumor model. Vaccine. 15: 387-94. PMID 9141209 DOI: 10.1016/S0264-410X(96)00195-8  0.44
1997 Rosenberg SA. Cancer vaccines based on the identification of genes encoding cancer regression antigens Immunology Today. 18: 175-182. PMID 9136454 DOI: 10.1016/S0167-5699(97)84664-6  0.44
1997 Kawakami Y, Rosenberg SA. Immunobiology of human melanoma antigens MART-1 and gp100 and their use for immuno-gene therapy. International Reviews of Immunology. 14: 173-92. PMID 9131386  1
1997 Zhai Y, Yang JC, Spiess P, Nishimura MI, Overwijk WW, Roberts B, Restifo NP, Rosenberg SA. Cloning and characterization of the genes encoding the murine homologues of the human melanoma antigens MART1 and gp100. Journal of Immunotherapy (Hagerstown, Md. : 1997). 20: 15-25. PMID 9101410 DOI: 10.1097/00002371-199701000-00002  0.44
1997 Bronte V, Carroll MW, Goletz TJ, Wang M, Overwijk WW, Marincola F, Rosenberg SA, Moss B, Restifo NP. Antigen expression by dendritic cells correlates with the therapeutic effectiveness of a model recombinant poxvirus tumor vaccine. Proceedings of the National Academy of Sciences of the United States of America. 94: 3183-8. PMID 9096367 DOI: 10.1073/pnas.94.7.3183  0.44
1997 Kawakami Y, Battles JK, Kobayashi T, Ennis W, Wang X, Tupesis JP, Marincola FM, Robbins PF, Hearing VJ, Gonda MA, Rosenberg SA. Production of recombinant MART-1 proteins and specific antiMART-1 polyclonal and monoclonal antibodies: use in the characterization of the human melanoma antigen MART-1. Journal of Immunological Methods. 202: 13-25. PMID 9075767 DOI: 10.1016/S0022-1759(96)00211-6  0.44
1997 Irvine KR, Chamberlain RS, Shulman EP, Rosenberg SA, Restifo NP. Route of immunization and the therapeutic impact of recombinant anticancer vaccines Journal of the National Cancer Institute. 89: 390-392. PMID 9060962  0.44
1997 Kang X, Robbins PF, Fitzgerald EB, Wang R, Rosenberg SA, Kawakami Y. Induction of melanoma reactive T cells by stimulator cells expressing melanoma epitope-major histocompatibility complex class I fusion proteins. Cancer Research. 57: 202-5. PMID 9000554  1
1996 Wang RF, Appella E, Kawakami Y, Kang X, Rosenberg SA. Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes. The Journal of Experimental Medicine. 184: 2207-16. PMID 8976176 DOI: 10.1084/jem.184.6.2207  0.48
1996 Rosenberg SA. Development of cancer immunotherapies based on identification of the genes encoding cancer regression antigens Journal of the National Cancer Institute. 88: 1635-1644. PMID 8931607 DOI: 10.1093/jnci/88.22.1635  0.44
1996 Kawakami Y, Rosenberg SA. T-cell recognition of self peptides as tumor rejection antigens. Immunologic Research. 15: 179-90. PMID 8902575  1
1996 Rosenberg SA, Kawakami Y, Robbins PF, Wang R. Identification of the genes encoding cancer antigens: implications for cancer immunotherapy. Advances in Cancer Research. 70: 145-77. PMID 8902056  1
1996 Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Oldfield E, Gansbacher B, Dunbar C, et al. Human gene marker/therapy clinical protocols. Human Gene Therapy. 7: 1621-47. PMID 8864763 DOI: 10.1089/hum.1996.7.13-1621  0.44
1996 Rosenberg SA, White DE. Vitiligo in patients with melanoma: Normal tissue antigens can be targets for cancer immunotherapy Journal of Immunotherapy. 19: 81-84. PMID 8859727 DOI: 10.1097/00002371-199601000-00009  0.44
1996 Lam JS, Reeves ME, Cowherd R, Rosenberg SA, Hwu P. Improved gene transfer into human lymphocytes using retroviruses with the gibbon ape leukemia virus envelope Human Gene Therapy. 7: 1415-1422. PMID 8844200 DOI: 10.1089/HUM.1996.7.12-1415  0.44
1996 Marincola FM, Hijazi YM, Fetsch P, Salgaller ML, Rivoltini L, Cormier J, Simonis TB, Duray PH, Herlyn M, Kawakami Y, Rosenberg SA. Analysis of expression of the melanoma-associated antigens MART-1 and gp100 in metastatic melanoma cell lines and in in situ lesions. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 19: 192-205. PMID 8811494 DOI: 10.1097/00002371-199605000-00004  1
1996 Parkhurst MR, Salgaller ML, Southwood S, Robbins PF, Sette A, Rosenberg SA, Kawakami Y. Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues. Journal of Immunology (Baltimore, Md. : 1950). 157: 2539-48. PMID 8805655  1
1996 Kawakami Y, Robbins PF, Wang RF, Rosenberg SA. Identification of tumor-regression antigens in melanoma. Important Advances in Oncology. 3-21. PMID 8791125  1
1996 Rosenberg SA. The immunotherapy of solid cancers based on cloning the genes encoding tumor-rejection antigens Annual Review of Medicine. 47: 481-491. PMID 8712798 DOI: 10.1146/annurev.med.47.1.481  0.44
1996 Kawakami Y, Robbins PF, Rosenberg SA. Human melanoma antigens recognized by T lymphocytes. The Keio Journal of Medicine. 45: 100-8. PMID 8683899  1
1996 Topalian SL, Gonzales MI, Parkhurst M, Li YF, Southwood S, Sette A, Rosenberg SA, Robbins PF. Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes. The Journal of Experimental Medicine. 183: 1965-71. PMID 8642306 DOI: 10.1084/JEM.183.5.1965  0.56
1996 Robbins PF, El-Gamil M, Li YF, Kawakami Y, Loftus D, Appella E, Rosenberg SA. A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes. The Journal of Experimental Medicine. 183: 1185-92. PMID 8642260 DOI: 10.1084/jem.183.3.1185  0.44
1996 Wang RF, Parkhurst MR, Kawakami Y, Robbins PF, Rosenberg SA. Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen. The Journal of Experimental Medicine. 183: 1131-40. PMID 8642255  0.44
1996 Yannelli JR, Hyatt C, McConnell S, Hines K, Jacknin L, Parker L, Sanders M, Rosenberg SA. Growth of tumor-infiltrating lymphocytes from human solid cancers: summary of a 5-year experience. International Journal of Cancer. Journal International Du Cancer. 65: 413-21. PMID 8621219 DOI: 10.1002/(SICI)1097-0215(19960208)65:4<413::AID-IJC3>3.0.CO;2-#  0.44
1996 Zhai Y, Yang JC, Kawakami Y, Spiess P, Wadsworth SC, Cardoza LM, Couture LA, Smith AE, Rosenberg SA. Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy. Journal of Immunology (Baltimore, Md. : 1950). 156: 700-10. PMID 8543823  1
1996 Rosenberg SA. Sounding board: Secrecy in medical research New England Journal of Medicine. 334: 392-394. PMID 8538713 DOI: 10.1056/NEJM199602083340610  0.44
1996 Restifo NP, Marincola FM, Kawakami Y, Taubenberger J, Yannelli JR, Rosenberg SA. Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy. Journal of the National Cancer Institute. 88: 100-8. PMID 8537970 DOI: 10.1093/jnci/88.2.100  0.44
1995 Wang M, Chen PW, Bronte V, Rosenberg SA, Restifo NP. Anti-tumor activity of cytotoxic T lymphocytes elicited with recombinant and synthetic forms of a model tumor-associated antigen. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 18: 139-46. PMID 8770769  0.44
1995 Krouse RS, Royal RE, Heywood G, Weintraub BD, White DE, Steinberg SM, Rosenberg SA, Schwartzentruber DJ. Thyroid dysfunction in 281 patients with metastatic melanoma or renal carcinoma treated with interleukin-2 alone. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 18: 272-8. PMID 8680655 DOI: 10.1097/00002371-199511000-00008  0.44
1995 Wang RF, Robbins PF, Kawakami Y, Kang XQ, Rosenberg SA. Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes. The Journal of Experimental Medicine. 181: 799-804. PMID 7836932 DOI: 10.1084/JEM.181.2.799  1
1995 Stevens EJ, Jacknin L, Robbins PF, Kawakami Y, el Gamil M, Rosenberg SA, Yannelli JR. Generation of tumor-specific CTLs from melanoma patients by using peripheral blood stimulated with allogeneic melanoma tumor cell lines. Fine specificity and MART-1 melanoma antigen recognition. Journal of Immunology (Baltimore, Md. : 1950). 154: 762-71. PMID 7814882  1
1995 Robbins PF, el-Gamil M, Li YF, Topalian SL, Rivoltini L, Sakaguchi K, Appella E, Kawakami Y, Rosenberg SA. Cloning of a new gene encoding an antigen recognized by melanoma-specific HLA-A24-restricted tumor-infiltrating lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 154: 5944-50. PMID 7751637  1
1995 Kawakami Y, Eliyahu S, Jennings C, Sakaguchi K, Kang X, Southwood S, Robbins PF, Sette A, Appella E, Rosenberg SA. Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression. Journal of Immunology (Baltimore, Md. : 1950). 154: 3961-8. PMID 7706734  1
1995 Heywood GR, Rosenberg SA, Weber JS. Hypersensitivity reactions to chemotherapy agents in patients receiving chemoimmunotherapy with high-dose interleukin 2. Journal of the National Cancer Institute. 87: 915-22. PMID 7666481 DOI: 10.1093/jnci/87.12.915  0.44
1995 Salgaller ML, Afshar A, Marincola FM, Rivoltini L, Kawakami Y, Rosenberg SA. Recognition of multiple epitopes in the human melanoma antigen gp100 by peripheral blood lymphocytes stimulated in vitro with synthetic peptides. Cancer Research. 55: 4972-9. PMID 7585538  1
1995 Koenig S, Conley AJ, Brewah YA, Jones GM, Leath S, Boots LJ, Davey V, Pantaleo G, Demarest JF, Carter C. Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression. Nature Medicine. 1: 330-6. PMID 7585062 DOI: 10.1038/nm0495-330  0.44
1995 Jakobsen MK, Restifo NP, Cohen PA, Marincola FM, Bryan Cheshire L, Marston Linehan W, Rosenberg SA, Alexander RB. Defective major histocompatibility complex class i expression in a sarcomatoid renal cell carcinoma cell line Journal of Immunotherapy. 17: 222-228. PMID 7582258  0.44
1995 Blaese RM, Culver KW, Miller AD, Carter CS, Fleisher T, Clerici M, Shearer G, Chang L, Chiang Y, Tolstoshev P, Greenblatt JJ, Rosenberg SA, Klein H, Berger M, Mullen CA, et al. T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years. Science (New York, N.Y.). 270: 475-80. PMID 7570001 DOI: 10.1126/science.270.5235.475  0.44
1995 Kang X, Kawakami Y, el-Gamil M, Wang R, Sakaguchi K, Yannelli JR, Appella E, Rosenberg SA, Robbins PF. Identification of a tyrosinase epitope recognized by HLA-A24-restricted, tumor-infiltrating lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 155: 1343-8. PMID 7543520  1
1995 Rivoltini L, Barracchini KC, Viggiano V, Kawakami Y, Smith A, Mixon A, Restifo NP, Topalian SL, Simonis TB, Rosenberg SA. Quantitative correlation between HLA class I allele expression and recognition of melanoma cells by antigen-specific cytotoxic T lymphocytes. Cancer Research. 55: 3149-57. PMID 7541714  1
1995 Cole DJ, Weil DP, Shilyansky J, Custer M, Kawakami Y, Rosenberg SA, Nishimura MI. Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen. Cancer Research. 55: 748-52. PMID 7531614  0.44
1994 Kawakami Y, Eliyahu S, Delgado CH, Robbins PF, Rivoltini L, Topalian SL, Miki T, Rosenberg SA. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proceedings of the National Academy of Sciences of the United States of America. 91: 3515-9. PMID 8170938 DOI: 10.1073/PNAS.91.9.3515  0.44
1994 Bakker AB, Schreurs MW, de Boer AJ, Kawakami Y, Rosenberg SA, Adema GJ, Figdor CG. Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes. The Journal of Experimental Medicine. 179: 1005-9. PMID 8113668 DOI: 10.1084/JEM.179.3.1005  0.44
1994 Rosenberg SA, Yannelli JR, Yang JC, Topalian SL, Schwartzentruber DJ, Weber JS, Parkinson DR, Seipp CA, Einhorn JH, White DE. Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2. Journal of the National Cancer Institute. 86: 1159-66. PMID 8028037 DOI: 10.1093/JNCI/86.15.1159  0.4
1994 Treisman J, Hwu P, Yannelli JR, Shafer GE, Cowherd R, Samid D, Rosenberg SA. Upregulation of tumor necrosis factor-alpha production by retrovirally transduced human tumor-infiltrating lymphocytes using trans-retinoic acid. Cellular Immunology. 156: 448-57. PMID 8025957 DOI: 10.1006/cimm.1994.1189  0.44
1994 Hwu P, Rosenberg SA. The use of gene-modified tumor-infiltrating lymphocytes for cancer therapy Annals of the New York Academy of Sciences. 716: 188-199. PMID 8024194 DOI: 10.1111/j.1749-6632.1994.tb21712.x  0.44
1994 Kawakami Y, Eliyahu S, Delgado CH, Robbins PF, Sakaguchi K, Appella E, Yannelli JR, Adema GJ, Miki T, Rosenberg SA. Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proceedings of the National Academy of Sciences of the United States of America. 91: 6458-62. PMID 8022805 DOI: 10.1073/PNAS.91.14.6458  0.4
1994 Schwartzentruber DJ, Hom SS, Dadmarz R, White DE, Yannelli JR, Steinberg SM, Rosenberg SA, Topalian SL. In vitro predictors of therapeutic response in melanoma patients receiving tumor-infiltrating lymphocytes and interleukin-2. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 12: 1475-83. PMID 8021739 DOI: 10.1200/JCO.1994.12.7.1475  0.4
1994 Topalian SL, Rivoltini L, Mancini M, Markus NR, Robbins PF, Kawakami Y, Rosenberg SA. Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene. Proceedings of the National Academy of Sciences of the United States of America. 91: 9461-5. PMID 7937789 DOI: 10.1073/PNAS.91.20.9461  0.32
1994 Cohen PJ, Cohen PA, Rosenberg SA, Katz SI, Mulé JJ. Murine epidermal Langerhans cells and splenic dendritic cells present tumor-associated antigens to primed T cells. European Journal of Immunology. 24: 315-9. PMID 7905414 DOI: 10.1002/eji.1830240206  0.44
1994 Rosenberg SA. The Gene Therapy of Cancer Preventive Medicine. 23: 624-626. PMID 7845927 DOI: 10.1006/pmed.1994.1102  0.44
1994 Nishimura MI, Kawakami Y, Charmley P, O'Neil B, Shilyansky J, Yannelli JR, Rosenberg SA, Hood L. T-cell receptor repertoire in tumor-infiltrating lymphocytes. Analysis of melanoma-specific long-term lines. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 16: 85-94. PMID 7804531 DOI: 10.1097/00002371-199408000-00002  0.44
1994 Cole DJ, Weil DP, Shamamian P, Rivoltini L, Kawakami Y, Topalian S, Jennings C, Eliyahu S, Rosenberg SA, Nishimura MI. Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope. Cancer Research. 54: 5265-8. PMID 7522957  1
1994 Shilyansky J, Nishimura MI, Yannelli JR, Kawakami Y, Jacknin LS, Charmley P, Rosenberg SA. T-cell receptor usage by melanoma-specific clonal and highly oligoclonal tumor-infiltrating lymphocyte lines. Proceedings of the National Academy of Sciences of the United States of America. 91: 2829-33. PMID 7511820 DOI: 10.1073/PNAS.91.7.2829  0.44
1993 Long JP, Walther MM, Alexander RB, Linehan WM, Rosenberg SA. The management of isolated renal recurrence of renal cell carcinoma following complete response to interleukin-2 based immunotherapy. The Journal of Urology. 150: 176-8. PMID 8510245 DOI: 10.1016/S0022-5347(17)35428-9  0.44
1993 Rosenberg SA, Lotze MT, Yang JC, Topalian SL, Chang AE, Schwartzentruber DJ, Aebersold P, Leitman S, Linehan WM, Seipp CA. Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer. Journal of the National Cancer Institute. 85: 622-32. PMID 8468720 DOI: 10.1093/jnci/85.8.622  0.44
1993 Restifo NP, Esquivel F, Kawakami Y, Yewdell JW, Mulé JJ, Rosenberg SA, Bennink JR. Identification of human cancers deficient in antigen processing Journal of Experimental Medicine. 177: 265-272. PMID 8426105  0.44
1993 Shiloni E, Karp SE, Custer MC, Shilyansky J, Restifo NP, Rosenberg SA, Mulé JJ. Retroviral transduction of interferon-gamma cDNA into a nonimmunogenic murine fibrosarcoma: generation of T cells in draining lymph nodes capable of treating established parental metastatic tumor. Cancer Immunology, Immunotherapy : Cii. 37: 286-92. PMID 8402732 DOI: 10.1007/BF01518450  0.44
1993 Walther MM, Alexander RB, Weiss GH, Venzon D, Berman A, Pass HI, Linehan WM, Rosenberg SA. Cytoreductive surgery prior to interleukin-2-based therapy in patients with metastatic renal cell carcinoma. Urology. 42: 250-7; discussion 25. PMID 8379024 DOI: 10.1016/0090-4295(93)90612-E  0.44
1993 Hwu P, Shafer GE, Treisman J, Schindler DG, Gross G, Cowherd R, Rosenberg SA, Eshhar Z. Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain. The Journal of Experimental Medicine. 178: 361-6. PMID 8315392 DOI: 10.1084/jem.178.1.361  0.44
1993 Restifo NP, Kawakami Y, Marincola F, Shamamian P, Taggarse A, Esquivel F, Rosenberg SA. Molecular mechanisms used by tumors to escape immune recognition: Immunogenetherapy and the cell biology of major histocompatibility complex class I Journal of Immunotherapy. 14: 182-190. PMID 8297900  0.44
1993 Kawakami Y, Nishimura MI, Restifo NP, Topalian SL, O'Neil BH, Shilyansky J, Yannelli JR, Rosenberg SA. T-cell recognition of human melanoma antigens. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 14: 88-93. PMID 8280705  0.44
1992 Jicha DL, Yannelli JR, Custer M, Colandrea J, Taubenberger J, Mulé JJ, Rosenberg SA. The persistence of human peripheral lymphocytes, tumor infiltrating lymphocytes, and colon adenocarcinomas in immunodeficient mice. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 11: 19-29. PMID 1734945 DOI: 10.1097/00002371-199201000-00003  0.4
1992 Rosenberg SA. The immunotherapy and gene therapy of cancer Journal of Clinical Oncology. 10: 180-199. PMID 1732421 DOI: 10.1200/JCO.1992.10.2.180  0.44
1992 Restifo NP, Spiess PJ, Karp SE, Mulé JJ, Rosenberg SA. A nonimmunogenic sarcoma transduced with the cDNA for interferon γ elicits CD8+ T cells against the wild-type tumor: Correlation with antigen presentation capability Journal of Experimental Medicine. 175: 1423-1431. PMID 1588273  0.44
1992 Alexander RB, Bolton ES, Koenig S, Jones GM, Topalian SL, June CH, Rosenberg SA. Detection of antigen specific T lymphocytes by determination of intracellular calcium concentration using flow cytometry. Journal of Immunological Methods. 148: 131-41. PMID 1564323 DOI: 10.1016/0022-1759(92)90166-Q  0.44
1992 Rosenberg SA. Gene Therapy for Cancer Jama: the Journal of the American Medical Association. 268: 2416-2419. PMID 1404800 DOI: 10.1001/jama.1992.03490170088031  0.44
1991 Aebersold P, Hyatt C, Johnson S, Hines K, Korcak L, Sanders M, Lotze M, Topalian S, Yang J, Rosenberg SA. Lysis of autologous melanoma cells by tumor-infiltrating lymphocytes: association with clinical response. Journal of the National Cancer Institute. 83: 932-7. PMID 2067036 DOI: 10.1093/JNCI/83.13.932  0.44
1991 Culver K, Cornetta K, Morgan R, Morecki S, Aebersold P, Kasid A, Lotze M, Rosenberg SA, Anderson WF, Blaese RM. Lymphocytes as cellular vehicles for gene therapy in mouse and man. Proceedings of the National Academy of Sciences of the United States of America. 88: 3155-9. PMID 2014235 DOI: 10.1073/pnas.88.8.3155  0.44
1991 Morecki S, Karson E, Cornetta K, Kasid A, Aebersold P, Blaese RM, Anderson WF, Rosenberg SA. Retrovirus-mediated gene transfer into CD4+ and CD8+ human T cell subsets derived from tumor-infiltrating lymphocytes and peripheral blood mononuclear cells. Cancer Immunology, Immunotherapy : Cii. 32: 342-52. PMID 2007247 DOI: 10.1007/BF01741329  0.44
1991 Lefor AT, Rosenberg SA. The specificity of lymphokine-activated killer (LAK) cells in vitro: fresh normal murine tissues are resistant to LAK-mediated lysis Journal of Surgical Research. 50: 15-23. PMID 1987427 DOI: 10.1016/0022-4804(91)90004-6  0.44
1991 Pockaj BA, Rosenberg SA. Lack of antihypertensive effect of interleukin-2 administration in humans Journal of Immunotherapy. 10: 456-459. PMID 1768680 DOI: 10.1097/00002371-199112000-00010  0.44
1990 Rosenberg SA, Aebersold P, Cornetta K, Kasid A, Morgan RA, Moen R, Karson EM, Lotze MT, Yang JC, Topalian SL, Merino MJ, Culver K, Miller AD, Blaese RM, Anderson WF. Gene transfer into humans - Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction New England Journal of Medicine. 323: 570-578. PMID 2381442 DOI: 10.1056/NEJM199008303230904  0.44
1990 Rosenberg SA. Adoptive immunotherapy for cancer Scientific American. 262: 62-69. PMID 2333496 DOI: 10.1038/SCIENTIFICAMERICAN0590-62  0.44
1990 Lotze MT, Custer MC, Bolton ES, Wiebke EA, Kawakami Y, Rosenberg SA. Mechanisms of immunologic antitumor therapy: lessons from the laboratory and clinical applications. Human Immunology. 28: 198-207. PMID 2190952 DOI: 10.1016/0198-8859(90)90020-P  0.44
1990 Weber JS, Rosenberg SA. Effects of murine tumor class i major histocompatibility complex expression on antitumor activity of tumor-infiltrating lymphocytes Journal of the National Cancer Institute. 82: 755-761. PMID 2109092 DOI: 10.1093/jnci/82.9.755  0.44
1989 Griffith KD, Read EJ, Carrasquillo JA, Carter CS, Yang JC, Fisher B, Aebersold P, Packard BS, Yu MY, Rosenberg SA. In vivo distribution of adoptively transferred indium-111-labeled tumor infiltrating lymphocytes and peripheral blood lymphocytes in patients with metastatic melanoma. Journal of the National Cancer Institute. 81: 1709-17. PMID 2810387 DOI: 10.1093/jnci/81.22.1709  0.44
1989 Saris SC, Patronas NJ, Rosenberg SA, Alexander JT, Frank J, Schwartzentruber DJ, Rubin JT, Barba D, Oldfield EH. The effect of intravenous interleukin-2 on brain water content Journal of Neurosurgery. 71: 169-174. PMID 2787395 DOI: 10.3171/JNS.1989.71.2.0169  0.44
1989 Fox BA, Rosenberg SA. Heterogeneous lymphokine-activated killer cell precursor populations - Development of a monoclonal antibody that separates two populations of precursors with distinct culture requirements and separate target-recognition repertoires Cancer Immunology Immunotherapy. 29: 155-166. PMID 2786456 DOI: 10.1007/BF00199990  0.44
1989 Chang AE, Rosenberg SA. Overview of interleukin-2 as an immunotherapeutic agent Seminars in Surgical Oncology. 5: 385-390. PMID 2688029 DOI: 10.1002/SSU.2980050604  0.44
1989 Rosenberg SA, Lotze MT, Yang JC, Aebersold PM, Linehan WM, Seipp CA, White DE. Experience with the use of high-dose interleukin-2 in the treatment of 652 cancer patients. Annals of Surgery. 210: 474-84; discussion 4. PMID 2679456 DOI: 10.1097/00000658-198910000-00008  0.44
1989 Rosenberg SA. Clinical immunotherapy studies in the surgery branch of the U.S. National Cancer Institute: brief review Cancer Treatment Reviews. 16: 115-121. PMID 2670208 DOI: 10.1016/0305-7372(89)90031-5  0.44
1989 Krosnick JA, McIntosh JK, Mulé JJ, Rosenberg SA. Studies of the mechanisms of toxicity of the administration of recombinant tumor necrosis factor alpha in normal and tumor-bearing mice. Cancer Immunology, Immunotherapy : Cii. 30: 133-8. PMID 2598182 DOI: 10.1007/BF01669420  0.44
1989 Belldegrun A, Rosenberg SA. Adoptive immunotherapy of urologic tumors Cancer Treatment and Research. 46: 213-233. PMID 2577191 DOI: 10.1007/978-1-4613-1595-7_12  0.44
1988 Eisenthal A, Rosenberg SA. Cross linking of anti-B16 melanoma monoclonal antibodies to lymphokine activated killer (LAK) cells: possible role in the therapy of B16 melanoma Clinical &Amp; Experimental Metastasis. 6: 387-400. PMID 3378376 DOI: 10.1007/BF01760574  0.44
1988 Rosenberg SA. Development of new immunologic approaches to cancer therapy Blood Purification. 6: 69-76. PMID 3293619 DOI: 10.1159/000169486  0.44
1988 Yang JC, Rosenberg SA. Current approaches to the adoptive immunotherapy of cancer Advances in Experimental Medicine and Biology. 233: 459-467. PMID 3265581 DOI: 10.1007/978-1-4899-5037-6_50  0.44
1988 Rosenberg SA, Packard BS, Aebersold PM, Solomon D, Topalian SL, Toy ST, Simon P, Lotze MT, Yang JC, Seipp CA. Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report. The New England Journal of Medicine. 319: 1676-80. PMID 3264384 DOI: 10.1056/NEJM198812223192527  0.44
1988 Kawakami Y, Rosenberg SA, Lotze MT. Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma Journal of Experimental Medicine. 168: 2183-2191. PMID 3264324 DOI: 10.1084/jem.168.6.2183  0.44
1988 Schwartzentruber D, Lotze MT, Rosenberg SA. Colonic perforation: An unusual complication of therapy with high-dose interleukin-2 Cancer. 62: 2350-2353. PMID 3263182 DOI: 10.1002/1097-0142(19881201)62:11<2350::AID-CNCR2820621116>3.0.CO;2-S  0.44
1988 Rosenberg SA, Schwarz SL, Spiess PJ. Combination immunotherapy for cancer: Synergistic antitumor interactions of interleukin-2, alfa interferon, and tumor-infiltrating lymphocytes Journal of the National Cancer Institute. 80: 1393-1397. PMID 3262772 DOI: 10.1093/jnci/80.17.1393  0.44
1988 Saris SC, Rosenberg SA, Friedman RB, Rubin JT, Barba D, Oldfield EH. Penetration of recombinant interleukin-2 across the blood-cerebrospinal fluid barrier Journal of Neurosurgery. 69: 29-34. PMID 3259980 DOI: 10.3171/JNS.1988.69.1.0029  0.44
1988 Rosenberg SA. Cancer therapy with interleukin-2: Immunologic manipulations can mediate the regression of cancer in humans Journal of Clinical Oncology. 6: 403-406. PMID 3258361 DOI: 10.1200/JCO.1988.6.3.403  0.44
1988 Rosenberg SA. The development of new immunotherapies for the treatment of cancer using interleukin-2. A review Annals of Surgery. 208: 121-135. PMID 3041925 DOI: 10.1097/00000658-198808000-00001  0.44
1988 Mulé JJ, Schwarz SL, Roberts AB, Sporn MB, Rosenberg SA. Transforming growth factor-beta inhibits the in vitro generation of lymphokine-activated killer cells and cytotoxic T cells Cancer Immunology Immunotherapy. 26: 95-100. PMID 2452015 DOI: 10.1007/BF00205600  0.44
1988 Lotze MT, Rosenberg SA. The immunologic treatment of cancer Ca-a Cancer Journal For Clinicians. 38: 68-94. PMID 2450624 DOI: 10.3322/canjclin.38.2.68  0.44
1988 Rosenberg SA. Immunotherapy of cancer using interleukin 2: current status and future prospects Trends in Immunology. 9: 63. DOI: 10.1016/0167-5699(88)91261-3  0.44
1987 Denicoff KD, Rubinow DR, Papa MZ, Simpson C, Seipp CA, Lotze MT, Chang AE, Rosenstein D, Rosenberg SA. The neuropsychiatric effects of treatment with interleukin-2 and lymphokine-activated killer cells. Annals of Internal Medicine. 107: 293-300. PMID 3497595 DOI: 10.7326/0003-4819-107-2-293  0.44
1987 Topalian SL, Rosenberg SA. Therapy of cancer using the adoptive transfer of activated killer cells and interleukin-2 Acta Haematologica. 78: 75-76. PMID 3124451 DOI: 10.1159/000205907  0.44
1987 Fauci AS, Rosenberg SA, Sherwin SA, Dinarello CA, Longo DL, Lane HC. NIH conference. Immunomodulators in clinical medicine Annals of Internal Medicine. 106: 421-433. PMID 2433978 DOI: 10.7326/0003-4819-106-3-421  0.44
1987 Lotze MT, Rosenberg SA. In Reply Jama: the Journal of the American Medical Association. 257: 1730-1731. DOI: 10.1001/jama.1987.03390130047019  0.44
1986 Ettinghausen SE, Rosenberg SA. The adoptive immunotherapy of cancer using lymphokine activated killer cells and recombinant interleukin-2 Springer Seminars in Immunopathology. 9: 51-71. PMID 3523804 DOI: 10.1007/BF00201905  0.44
1986 Lotze MT, Custer MC, Rosenberg SA. Intraperitoneal Administration of Interleukin-2 in Patients With Cancer Archives of Surgery. 121: 1373-1379. PMID 3491595 DOI: 10.1001/archsurg.1986.01400120019002  0.44
1986 Lotze MT, Matory YL, Rayner AA, Ettinghausen SE, Vetto JT, Seipp CA, Rosenberg SA. Clinical effects and toxicity of interleukin-2 in patients with cancer. Cancer. 58: 2764-72. PMID 3490903 DOI: 10.1002/1097-0142(19861215)58:12<2764::AID-CNCR2820581235>3.0.CO;2-Z  0.44
1986 Lotze MT, Rosenberg SA. Results of clinical trials with the administration of interleukin 2 and adoptive immunotherapy with activated cells in patients with cancer Immunobiology. 172: 420-437. PMID 3100435 DOI: 10.1016/S0171-2985(86)80122-X  0.44
1985 Kaufmann Y, Moscovitch M, Robb RJ, Rosenberg SA, Berke G. Antigen/mitogen induced cytolytic activity and IL-2 secretion in memory-like CTL-hybridomas. Advances in Experimental Medicine and Biology. 184: 535-50. PMID 3929574  0.44
1985 Shapiro E, Kinsella TJ, Makuch RW, Fraass BA, Glatstein E, Rosenberg SA, Sherins RJ. Effects of fractionated irradiation on endocrine aspects of testicular function Journal of Clinical Oncology. 3: 1232-1239. PMID 3928830  0.44
1985 Rosenberg SA, Mule JJ, Spiess PJ, Reichert CM, Schwarz SL. Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2 Journal of Experimental Medicine. 161: 1169-1188. PMID 3886826 DOI: 10.1084/jem.161.5.1169  0.44
1985 Sharp TA, Gress RE, Sachs DH, Rosenberg SA. Assessment of mixed lymphocyte reactivity in human bone marrow cell cultures Transplantation. 40: 551-556. PMID 2932821 DOI: 10.1097/00007890-198511000-00015  0.44
1984 Kaufmann Y, Rosenberg SA. Blocking by cyclosporine of antigen–induced maturation and lymphokine secretion by cytotoxic T lymphocyte hybridomas Transplantation. 38: 148-151. PMID 6611618 DOI: 10.1097/00007890-198408000-00011  0.44
1984 Rosenstein M, Rosenberg SA. Generation of lytic and proliferative lymphoid clones to syngeneic tumor: In vitro and in vivo studies Journal of the National Cancer Institute. 72: 1161-1165. PMID 6609266 DOI: 10.1093/jnci/72.5.1161  0.44
1984 Sharp TG, Sachs DH, Matthews JG, Maples J, Woody JN, Rosenberg SA. Harvest of human bone marrow directly from bone Journal of Immunological Methods. 69: 187-195. PMID 6609206 DOI: 10.1016/0022-1759(84)90317-X  0.44
1984 Mulé JJ, Shu S, Schwarz SL, Rosenberg SA. Adoptive immunotherapy of esablished pulmonary metastases with LAK cells and recombinant interleukin-2 Science. 225: 1487-1489. PMID 6332379 DOI: 10.1126/SCIENCE.6332379  0.44
1984 Mazumder A, Rosenberg SA. Successful immunotherapy of natural killer-resistant established pulmonary melanoma metastases by the intravenous adoptive transfer of syngeneic lymphocytes activated in vitro by interleukin 2 Journal of Experimental Medicine. 159: 495-507. PMID 6141211 DOI: 10.1084/JEM.159.2.495  0.44
1984 Lotze MT, Rosenberg SA. In vivo use of cytokines Clinical Immunology Newsletter. 5: 116-120. DOI: 10.1016/S0197-1859(84)80031-X  0.44
1983 Dresdale A, Bonow RO, Wesley R, Palmeri ST, Barr L, Mathison D, D'Angelo T, Rosenberg SA. Prospective evaluation of doxorubicin-induced cardiomyopathy resulting from postsurgical adjuvant treatment of patients with soft tissue sarcomas Cancer. 52: 51-60. PMID 6850545 DOI: 10.1002/1097-0142(19830701)52:1<51::AID-CNCR2820520111>3.0.CO;2-#  0.44
1983 Grimm EA, Ramsey KM, Mazumder A, Wilson DJ, Djeu JY, Rosenberg SA. Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells Journal of Experimental Medicine. 157: 884-892. PMID 6601174 DOI: 10.1084/JEM.157.3.884  0.44
1981 Spiess PJ, Rosenberg SA. A simplified method for the production of murine T-cell growth factor free of lectin Journal of Immunological Methods. 42: 213-222. PMID 6972416 DOI: 10.1016/0022-1759(81)90151-4  0.44
1980 Mathisen DJ, Rosenberg SA. Comparison of in vivo cell distribution following either intraperitoneal or intravenous injection of lymphoid cells Transplantation. 29: 347-349. PMID 7368282 DOI: 10.1097/00007890-198004000-00020  0.44
1979 Levine AM, Rosenberg SA. Alkaline phosphatase levels in osteosarcoma tissue are related to prognosis Cancer. 44: 2291-2293. PMID 292511 DOI: 10.1002/1097-0142(197912)44:6<2291::AID-CNCR2820440643>3.0.CO;2-S  0.44
1977 Cohen MH, Ketcham AS, Felix EL, Li SH, Tomaszewski MM, Costa J, Rabson AS, Simon RM, Rosenberg SA. Prognostic factors in patients undergoing lymphadenectomy for malignant melanoma Annals of Surgery. 186: 635-642. PMID 921357 DOI: 10.1097/00000658-197711000-00016  0.44
1977 Parker GA, Rosenberg SA. Serologic identification of multiple tumor-associated antigens on murine sarcomas Journal of the National Cancer Institute. 58: 1303-1309. PMID 67211 DOI: 10.1093/jnci/58.5.1303  0.44
1977 Rosenberg SA. Lysis of human normal and sarcoma cells in tissue culture by normal human serum: Implications for experiments in human tumor immunology Journal of the National Cancer Institute. 58: 1233-1238. PMID 67209 DOI: 10.1093/jnci/58.5.1233  0.44
1975 Rosenberg SA. Future prospects for immunotherapy Cancer. 36: 821-824. PMID 168962 DOI: 10.1002/1097-0142(197508)36:2+<821::AID-CNCR2820360829>3.0.CO;2-U  0.44
1974 Rosenberg SA, Schwarz S. Murine autoantibodies to a cryptic membrane antigen: possible explanation for neuraminidase induced increase in cell immunogenicity Journal of the National Cancer Institute. 52: 1151-1155. PMID 4826586 DOI: 10.1093/JNCI/52.4.1151  0.44
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