Year |
Citation |
Score |
2016 |
Taylor AM, Côté A, Hewitt MC, Pastor R, Leblanc Y, Nasveschuk CG, Romero FA, Crawford TD, Cantone N, Jayaram H, Setser J, Murray J, Beresini MH, de Leon Boenig G, Chen Z, ... ... Huang OW, et al. Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). Acs Medicinal Chemistry Letters. 7: 531-536. PMID 27190605 DOI: 10.1021/Acsmedchemlett.6B00075 |
0.583 |
|
2015 |
Flynn EM, Huang OW, Poy F, Oppikofer M, Bellon SF, Tang Y, Cochran AG. A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications. Structure (London, England : 1993). PMID 26365797 DOI: 10.1016/J.Str.2015.08.004 |
0.594 |
|
2015 |
Taherbhoy AM, Huang OW, Cochran AG. BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase. Nature Communications. 6: 7621. PMID 26151332 DOI: 10.1038/Ncomms8621 |
0.604 |
|
2015 |
Rutz S, Kayagaki N, Phung QT, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang OW, Cochran AG, Vasser M, Fauber BP, DeVoss J, Webster J, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 518: 417-21. PMID 25470037 DOI: 10.1038/Nature13979 |
0.529 |
|
2013 |
Huang OW, Cochran AG. Regulation of deubiquitinase proteolytic activity. Current Opinion in Structural Biology. 23: 806-11. PMID 23962487 DOI: 10.1016/J.Sbi.2013.07.012 |
0.615 |
|
2012 |
Huang OW, Ma X, Yin J, Flinders J, Maurer T, Kayagaki N, Phung Q, Bosanac I, Arnott D, Dixit VM, Hymowitz SG, Starovasnik MA, Cochran AG. Phosphorylation-dependent activity of the deubiquitinase DUBA Nature Structural and Molecular Biology. 19: 171-176. PMID 22245969 DOI: 10.1038/Nsmb.2206 |
0.601 |
|
2011 |
Bourhis E, Wang W, Tam C, Hwang J, Zhang Y, Spittler D, Huang OW, Gong Y, Estevez A, Zilberleyb I, Rouge L, Chiu C, Wu Y, Costa M, Hannoush RN, et al. Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6. Structure (London, England : 1993). 19: 1433-42. PMID 21944579 DOI: 10.1016/J.Str.2011.07.005 |
0.586 |
|
2009 |
Aliagas-Martin I, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Huang OW, Hunsaker T, Kleinheinz T, Krueger E, Liang J, Moffat J, Phillips G, Pulk R, Rawson TE, et al. A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B. Journal of Medicinal Chemistry. 52: 3300-7. PMID 19402633 DOI: 10.1021/Jm9000314 |
0.589 |
|
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