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David G. Schatz, PhD - Publications

Affiliations: 
Immunobiology Yale University, New Haven, CT 
Area:
immunology
Website:
http://medicine.yale.edu/mbb/faculty/david_schatz.profile

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wu L, Shukla V, Yadavalli AD, Dinesh RK, Xu D, Rao A, Schatz DG. HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation. Genes & Development. 36: 433-450. PMID 35450882 DOI: 10.1101/gad.349438.122  0.346
2021 Tarsalainen A, Maman Y, Meng FL, Kyläniemi MK, Soikkeli A, Budzyńska P, McDonald JJ, Šenigl F, Alt FW, Schatz DG, Alinikula J. Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences. Journal of Immunology (Baltimore, Md. : 1950). PMID 34862258 DOI: 10.4049/jimmunol.2100923  0.604
2021 Liu C, Zhang Y, Liu CC, Schatz DG. Structural insights into the evolution of the RAG recombinase. Nature Reviews. Immunology. PMID 34675378 DOI: 10.1038/s41577-021-00628-6  0.306
2021 Beilinson HA, Glynn RA, Yadavalli AD, Xiao J, Corbett E, Saribasak H, Arya R, Miot C, Bhattacharyya A, Jones JM, Pongubala JMR, Bassing CH, Schatz DG. The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination. The Journal of Experimental Medicine. 218. PMID 34402853 DOI: 10.1084/jem.20210250  0.331
2020 Zhang Y, Corbett E, Wu S, Schatz DG. Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase. The Embo Journal. e105857. PMID 32945578 DOI: 10.15252/Embj.2020105857  0.4
2020 Weinmann AS, Youngblood BA, Smale ST, Brink R, Schatz DG, McHeyzer-Williams M. A Future Outlook on Molecular Mechanisms of Immunity. Trends in Immunology. PMID 32507312 DOI: 10.1016/J.It.2020.05.005  0.511
2020 Kuhny M, Forbes LR, Çakan E, Vega-Loza A, Kostiuk V, Dinesh RK, Glauzy S, Stray-Pedersen A, Pezzi AE, Hanson IC, Vargas-Hernandez A, Xu ML, Coban Akdemir ZH, Jhangiani SN, Muzny DM, ... ... Schatz DG, et al. Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID. The Journal of Clinical Investigation. PMID 32484799 DOI: 10.1172/Jci131297  0.401
2020 Hirokawa S, Chure G, Belliveau NM, Lovely GA, Anaya M, Schatz DG, Baltimore D, Phillips R. Sequence-dependent dynamics of synthetic and endogenous RSSs in V(D)J recombination. Nucleic Acids Research. PMID 32449932 DOI: 10.1093/Nar/Gkaa418  0.642
2020 Martin EC, Vicari C, Tsakou-Ngouafo L, Pontarotti P, Petrescu AJ, Schatz DG. Identification of RAG-like transposons in protostomes suggests their ancient bilaterian origin. Mobile Dna. 11: 17. PMID 32399063 DOI: 10.1186/S13100-020-00214-Y  0.399
2020 Brecht RM, Liu CC, Beilinson HA, Khitun A, Slavoff SA, Schatz DG. Nucleolar localization of RAG1 modulates V(D)J recombination activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32047031 DOI: 10.1073/Pnas.1920021117  0.488
2019 Shinoda K, Maman Y, Canela A, Schatz DG, Livak F, Nussenzweig A. Intra-Vκ Cluster Recombination Shapes the Ig Kappa Locus Repertoire. Cell Reports. 29: 4471-4481.e6. PMID 31875554 DOI: 10.1016/J.Celrep.2019.11.088  0.42
2019 Senigl F, Maman Y, Dinesh RK, Alinikula J, Seth RB, Pecnova L, Omer AD, Rao SSP, Weisz D, Buerstedde JM, Aiden EL, Casellas R, Hejnar J, Schatz DG. Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation. Cell Reports. 29: 3902-3915.e8. PMID 31851922 DOI: 10.1016/J.Celrep.2019.11.039  0.398
2019 Dinesh RK, Barnhill B, Ilanges A, Wu L, Michelson DA, Senigl F, Alinikula J, Shabanowitz J, Hunt DF, Schatz DG. Transcription factor binding at immunoglobulin enhancers is linked to somatic hypermutation targeting. European Journal of Immunology. PMID 31821534 DOI: 10.1002/Eji.201948357  0.435
2019 Liu C, Yang Y, Schatz DG. Structures of a RAG-like transposase during cut-and-paste transposition. Nature. PMID 31723264 DOI: 10.1038/S41586-019-1753-7  0.37
2019 Lio CJ, Shukla V, Samaniego-Castruita D, González-Avalos E, Chakraborty A, Yue X, Schatz DG, Ay F, Rao A. TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the superenhancer. Science Immunology. 4. PMID 31028100 DOI: 10.1126/Sciimmunol.Aau7523  0.419
2019 Zhang Y, Cheng TC, Huang G, Lu Q, Surleac MD, Mandell JD, Pontarotti P, Petrescu AJ, Xu A, Xiong Y, Schatz DG. Transposon molecular domestication and the evolution of the RAG recombinase. Nature. PMID 30971819 DOI: 10.1038/s41586-019-1093-7  0.321
2019 Dinesh RK, Barnhill B, Ilanges A, Wu L, Michelson DA, Senigl F, Alinikula J, Shabanowitz J, Hunt DF, Schatz DG. Author response for "Transcription factor binding at immunoglobulin enhancers is linked to somatic hypermutation targeting" European Journal of Immunology. DOI: 10.1002/Eji.201948357/V2/Response1  0.304
2018 Ru H, Mi W, Zhang P, Alt FW, Schatz DG, Liao M, Wu H. DNA melting initiates the RAG catalytic pathway. Nature Structural & Molecular Biology. PMID 30061602 DOI: 10.1038/s41594-018-0098-5  0.533
2018 Hirokawa S, Belliveau NM, Lovely GA, Anaya M, Schatz DG, Baltimore D, Phillips R. Skewing the Playing Field: A Single-Molecule Study on how RSS Sequence Influences Gene Segment Selection Biophysical Journal. 114: 86a. DOI: 10.1016/J.Bpj.2017.11.511  0.631
2017 Fisher MR, Rivera-Reyes A, Bloch NB, Schatz DG, Bassing CH. Immature Lymphocytes Inhibit Rag1 and Rag2 Transcription and V(D)J Recombination in Response to DNA Double-Strand Breaks. Journal of Immunology (Baltimore, Md. : 1950). PMID 28213501 DOI: 10.4049/Jimmunol.1601639  0.472
2016 Carmona LM, Schatz DG. New insights into the evolutionary origins of the RAG proteins and V(D)J recombination. The Febs Journal. PMID 27973733 DOI: 10.1111/Febs.13990  0.448
2016 Maman Y, Teng G, Seth R, Kleinstein SH, Schatz DG. RAG1 targeting in the genome is dominated by chromatin interactions mediated by the non-core regions of RAG1 and RAG2. Nucleic Acids Research. PMID 27436288 DOI: 10.1093/Nar/Gkw633  0.379
2016 Huang S, Tao X, Yuan S, Zhang Y, Li P, Beilinson HA, Zhang Y, Yu W, Pontarotti P, Escriva H, Le Petillon Y, Liu X, Chen S, Schatz DG, Xu A. Discovery of an Active RAG Transposon Illuminates the Origins of V(D)J Recombination. Cell. PMID 27293192 DOI: 10.1016/J.Cell.2016.05.032  0.48
2016 Carmona LM, Fugmann SD, Schatz DG. Collaboration of RAG2 with RAG1-like proteins during the evolution of V(D)J recombination. Genes & Development. PMID 27056670 DOI: 10.1101/Gad.278432.116  0.456
2016 Williams AM, Maman Y, Alinikula J, Schatz DG. Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells. Plos One. 11: e0149146. PMID 26900682 DOI: 10.1371/Journal.Pone.0149146  0.469
2016 Hu J, Zhang Y, Zhao L, Frock R, Du Z, Meyers RM, Meng F, Schatz DG, Alt FW. Abstract A180: Topologically associated domains genome-wide restrict the off-target activity of recombination activating gene 1/2 endonuclease Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A180  0.592
2015 Hu J, Zhang Y, Zhao L, Frock RL, Du Z, Meyers RM, Meng FL, Schatz DG, Alt FW. Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes. Cell. 163: 947-59. PMID 26593423 DOI: 10.1016/J.Cell.2015.10.016  0.575
2015 Teng G, Schatz DG. Regulation and Evolution of the RAG Recombinase. Advances in Immunology. 128: 1-39. PMID 26477364 DOI: 10.1016/Bs.Ai.2015.07.002  0.475
2015 Shetty K, Schatz DG. Recruitment of RAG1 and RAG2 to Chromatinized DNA during V(D)J Recombination. Molecular and Cellular Biology. 35: 3701-13. PMID 26303526 DOI: 10.1128/Mcb.00219-15  0.482
2015 Mandal M, Hamel KM, Maienschein-Cline M, Tanaka A, Teng G, Tuteja JH, Bunker JJ, Bahroos N, Eppig JJ, Schatz DG, Clark MR. Histone reader BRWD1 targets and restricts recombination to the Igk locus. Nature Immunology. PMID 26301565 DOI: 10.1038/Ni.3249  0.467
2015 Teng G, Maman Y, Resch W, Kim M, Yamane A, Qian J, Kieffer-Kwon KR, Mandal M, Ji Y, Meffre E, Clark MR, Cowell LG, Casellas R, Schatz DG. RAG Represents a Widespread Threat to the Lymphocyte Genome. Cell. 162: 751-65. PMID 26234156 DOI: 10.1016/J.Cell.2015.07.009  0.38
2015 Choi J, Goh G, Walradt T, Hong BS, Bunick CG, Chen K, Bjornson RD, Maman Y, Wang T, Tordoff J, Carlson K, Overton JD, Liu KJ, Lewis JM, Devine L, ... ... Schatz DG, et al. Genomic landscape of cutaneous T cell lymphoma. Nature Genetics. PMID 26192916 DOI: 10.1038/Ng.3356  0.392
2015 Swaminathan S, Klemm L, Park E, Papaemmanuil E, Ford A, Kweon SM, Trageser D, Hasselfeld B, Henke N, Mooster J, Geng H, Schwarz K, Kogan SC, Casellas R, Schatz DG, et al. Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia. Nature Immunology. 16: 766-74. PMID 25985233 DOI: 10.1038/Ni.3160  0.328
2015 Lovely GA, Brewster RC, Schatz DG, Baltimore D, Phillips R. Single-molecule analysis of RAG-mediated V(D)J DNA cleavage. Proceedings of the National Academy of Sciences of the United States of America. 112: E1715-23. PMID 25831509 DOI: 10.1073/Pnas.1503477112  0.631
2015 Zhang YH, Shetty K, Surleac MD, Petrescu AJ, Schatz DG. Mapping and Quantitation of the Interaction between the Recombination Activating Gene Proteins RAG1 and RAG2. The Journal of Biological Chemistry. 290: 11802-17. PMID 25745109 DOI: 10.1074/Jbc.M115.638627  0.367
2015 Rodgers W, Byrum JN, Sapkota H, Rahman NS, Cail RC, Zhao S, Schatz DG, Rodgers KK. Spatio-temporal regulation of RAG2 following genotoxic stress. Dna Repair. 27: 19-27. PMID 25625798 DOI: 10.1016/J.Dnarep.2014.12.008  0.418
2015 Ciubotaru M, Surleac MD, Metskas LA, Koo P, Rhoades E, Petrescu AJ, Schatz DG. The architecture of the 12RSS in V(D)J recombination signal and synaptic complexes. Nucleic Acids Research. 43: 917-31. PMID 25550426 DOI: 10.1093/Nar/Gku1348  0.372
2015 Klemm L, Swaminathan S, Papaemmanuil E, Ford AM, Greaves M, Casellas R, Schatz D, Lieber MR, Muschen M. Exposure to Inflammatory Immune Responses As Driver of Clonal Evolution in Childhood Acute Lymphoblastic Leukemia Blood. 126: 166-166. DOI: 10.1182/Blood.V126.23.166.166  0.388
2014 Alinikula J, Schatz DG. Super-enhancer transcription converges on AID. Cell. 159: 1490-2. PMID 25525869 DOI: 10.1016/J.Cell.2014.12.007  0.39
2014 Karo JM, Schatz DG, Sun JC. The RAG recombinase dictates functional heterogeneity and cellular fitness in natural killer cells. Cell. 159: 94-107. PMID 25259923 DOI: 10.1016/J.Cell.2014.08.026  0.442
2014 Buerstedde JM, Lowndes N, Schatz DG. Induction of homologous recombination between sequence repeats by the activation induced cytidine deaminase (AID) protein. Elife. 3: e03110. PMID 25006166 DOI: 10.7554/Elife.03110  0.316
2014 Banerjee JK, Schatz DG. Synapsis alters RAG-mediated nicking at Tcrb recombination signal sequences: implications for the “beyond 12/23” rule. Molecular and Cellular Biology. 34: 2566-80. PMID 24797073 DOI: 10.1128/Mcb.00411-14  0.705
2014 Buerstedde JM, Alinikula J, Arakawa H, McDonald JJ, Schatz DG. Targeting of somatic hypermutation by immunoglobulin enhancer and enhancer-like sequences. Plos Biology. 12: e1001831. PMID 24691034 DOI: 10.1371/Journal.Pbio.1001831  0.666
2014 Buerstedde J, Lowndes N, Schatz DG. Author response: Induction of homologous recombination between sequence repeats by the activation induced cytidine deaminase (AID) protein Elife. DOI: 10.7554/Elife.03110.014  0.309
2014 Swaminathan S, Klemm L, Park E, Ford AM, Kweon S, Trageser D, Hasselfeld B, Henke N, Geng H, Schwarz K, Casellas R, Schatz DG, Lieber MR, Papaemmanuil E, Greaves M, et al. Mechanisms of Clonal Evolution of Pre-Leukemic Clones in Childhood Pre-B Acute Lymphoblastic Leukemia Blood. 124: 861-861. DOI: 10.1182/Blood.V124.21.861.861  0.435
2014 Lovely G, Linden M, Ramesh P, Schatz D, Baltimore D, Phillips R. Single Molecule Dynamics Governing the Initiation of V(D)J Recombination Biophysical Journal. 106: 692a. DOI: 10.1016/J.Bpj.2013.11.3826  0.437
2014 Little AJ, Matthews A, Oettinger M, Roth DB, Schatz DG. The Mechanism of V(D)J Recombination Molecular Biology of B Cells: Second Edition. 13-34. DOI: 10.1016/B978-0-12-397933-9.00002-3  0.665
2013 Chan EA, Teng G, Corbett E, Choudhury KR, Bassing CH, Schatz DG, Krangel MS. Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2. Proceedings of the National Academy of Sciences of the United States of America. 110: E4628-37. PMID 24218622 DOI: 10.1073/Pnas.1310846110  0.435
2013 McDonald JJ, Alinikula J, Buerstedde JM, Schatz DG. A critical context-dependent role for E boxes in the targeting of somatic hypermutation. Journal of Immunology (Baltimore, Md. : 1950). 191: 1556-66. PMID 23836058 DOI: 10.4049/Jimmunol.1300969  0.641
2013 Duke JL, Liu M, Yaari G, Khalil AM, Tomayko MM, Shlomchik MJ, Schatz DG, Kleinstein SH. Multiple transcription factor binding sites predict AID targeting in non-Ig genes. Journal of Immunology (Baltimore, Md. : 1950). 190: 3878-88. PMID 23514741 DOI: 10.4049/Jimmunol.1202547  0.414
2013 Chaumeil J, Micsinai M, Ntziachristos P, Deriano L, Wang JM, Ji Y, Nora EP, Rodesch MJ, Jeddeloh JA, Aifantis I, Kluger Y, Schatz DG, Skok JA. Higher-order looping and nuclear organization of Tcra facilitate targeted rag cleavage and regulated rearrangement in recombination centers. Cell Reports. 3: 359-70. PMID 23416051 DOI: 10.1016/J.Celrep.2013.01.024  0.427
2013 Steinel NC, Lee BS, Tubbs AT, Bednarski JJ, Schulte E, Yang-Iott KS, Schatz DG, Sleckman BP, Bassing CH. The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements. The Journal of Experimental Medicine. 210: 233-9. PMID 23382544 DOI: 10.1084/Jem.20121605  0.442
2013 Little AJ, Corbett E, Ortega F, Schatz DG. Cooperative recruitment of HMGB1 during V(D)J recombination through interactions with RAG1 and DNA. Nucleic Acids Research. 41: 3289-301. PMID 23325855 DOI: 10.1093/Nar/Gks1461  0.72
2013 Ciubotaru M, Trexler AJ, Spiridon LN, Surleac MD, Rhoades E, Petrescu AJ, Schatz DG. RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes. Nucleic Acids Research. 41: 2437-54. PMID 23293004 DOI: 10.1093/Nar/Gks1294  0.394
2012 Subrahmanyam R, Du H, Ivanova I, Chakraborty T, Ji Y, Zhang Y, Alt FW, Schatz DG, Sen R. Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctions. Nature Immunology. 13: 1205-12. PMID 23104096 DOI: 10.1038/Ni.2447  0.496
2012 Kohler KM, McDonald JJ, Duke JL, Arakawa H, Tan S, Kleinstein SH, Buerstedde JM, Schatz DG. Identification of core DNA elements that target somatic hypermutation. Journal of Immunology (Baltimore, Md. : 1950). 189: 5314-26. PMID 23087403 DOI: 10.4049/Jimmunol.1202082  0.819
2012 Farago M, Rosenbluh C, Tevlin M, Fraenkel S, Schlesinger S, Masika H, Gouzman M, Teng G, Schatz D, Rais Y, Hanna JH, Mildner A, Jung S, Mostoslavsky G, Cedar H, et al. Clonal allelic predetermination of immunoglobulin-κ rearrangement Nature. 490: 561-565. PMID 23023124 DOI: 10.1038/Nature11496  0.647
2012 Coster G, Gold A, Chen D, Schatz DG, Goldberg M. A dual interaction between the DNA damage response protein MDC1 and the RAG1 subunit of the V(D)J recombinase. The Journal of Biological Chemistry. 287: 36488-98. PMID 22942284 DOI: 10.1074/Jbc.M112.402487  0.404
2012 Gramlich HS, Reisbig T, Schatz DG. AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells. Plos One. 7: e39601. PMID 22768095 DOI: 10.1371/Journal.Pone.0039601  0.798
2012 Koduru S, Wong E, Strowig T, Sundaram R, Zhang L, Strout MP, Flavell RA, Schatz DG, Dhodapkar KM, Dhodapkar MV. Dendritic cell-mediated activation-induced cytidine deaminase (AID)-dependent induction of genomic instability in human myeloma. Blood. 119: 2302-9. PMID 22234692 DOI: 10.1182/Blood-2011-08-376236  0.329
2012 Swaminathan S, Klemm L, Ford AM, Schwarz K, Casellas R, Hennighausen L, Geng H, Schatz DG, Lieber MR, Greaves M, Muschen M. Cooperation Between Aid and the Rag1/Rag2 V(D)J Recombinase Drives Clonal Evolution of Childhood Acute Lymphoblastic Leukemia Blood. 120: 519-519. DOI: 10.1182/Blood.V120.21.519.519  0.442
2012 Koduru S, Wong E, Strowig T, Sundaram R, Zhang L, Strout MP, Flavell RA, Schatz DG, Dhodapkar KM, Dhodapkar MV. Abstract 309: Induction of activation-induced cytidine deaminase (AID) by dendritic cells leads to genomic instability in human myeloma Cancer Research. 72: 309-309. DOI: 10.1158/1538-7445.Am2012-309  0.312
2011 Schatz DG, Swanson PC. V(D)J recombination: mechanisms of initiation. Annual Review of Genetics. 45: 167-202. PMID 21854230 DOI: 10.1146/Annurev-Genet-110410-132552  0.453
2011 Seitan VC, Hao B, Tachibana-Konwalski K, Lavagnolli T, Mira-Bontenbal H, Brown KE, Teng G, Carroll T, Terry A, Horan K, Marks H, Adams DJ, Schatz DG, Aragon L, Fisher AG, et al. A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature. 476: 467-71. PMID 21832993 DOI: 10.1038/Nature10312  0.448
2011 Schatz DG, Ji Y. Recombination centres and the orchestration of V(D)J recombination. Nature Reviews. Immunology. 11: 251-63. PMID 21394103 DOI: 10.1038/Nri2941  0.484
2011 Maul RW, Saribasak H, Martomo SA, McClure RL, Yang W, Vaisman A, Gramlich HS, Schatz DG, Woodgate R, Wilson DM, Gearhart PJ. Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions. Nature Immunology. 12: 70-6. PMID 21151102 DOI: 10.1038/Ni.1970  0.786
2011 Klemm L, Swaminathan S, Ford AM, Schwarz K, Schatz DG, Lieber MR, Greaves MF, Muschen M. Infectious Origins of Childhood Leukemia Blood. 118: 751-751. DOI: 10.1182/Blood.V118.21.751.751  0.418
2011 Gu X, Booth CJ, Schatz DG, Strout MP. The Role of DNA Repair in the Pathogenesis of Activation Induced Cytidine Deaminase Dependent B Cell Lymphoma Blood. 118: 397-397. DOI: 10.1182/Blood.V118.21.397.397  0.453
2011 Strout MP, Philip N, Schatz DG. Regulation of the Mutation Threshold During Immune Diversification by Activation Induced Cytidine Deaminase, Blood. 118: 3244-3244. DOI: 10.1182/Blood.V118.21.3244.3244  0.46
2010 Ji Y, Little AJ, Banerjee JK, Hao B, Oltz EM, Krangel MS, Schatz DG. Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination. The Journal of Experimental Medicine. 207: 2809-16. PMID 21115692 DOI: 10.1084/Jem.20101136  0.813
2010 Lazorchak AS, Liu D, Facchinetti V, Di Lorenzo A, Sessa WC, Schatz DG, Su B. Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells. Molecular Cell. 39: 433-43. PMID 20705244 DOI: 10.1016/J.Molcel.2010.07.031  0.436
2010 Ji Y, Resch W, Corbett E, Yamane A, Casellas R, Schatz DG. The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci. Cell. 141: 419-31. PMID 20398922 DOI: 10.1016/J.Cell.2010.03.010  0.436
2010 Swaminathan S, Klemm L, Kweon S, Ford A, Schwarz K, Casellas R, Hennighausen L, Schatz DG, Lieber MR, Greaves MF, Muschen M. IL7Rα Signaling Prevents Premature Expression of AID In Human Pre-B Cells: Implications for Clonal Evolution of Childhood Leukemia Blood. 116: 26-26. DOI: 10.1182/Blood.V116.21.26.26  0.422
2009 Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, et al. RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nature Immunology. 10: 655-64. PMID 19448632 DOI: 10.1038/Ni.1735  0.412
2009 Yin FF, Bailey S, Innis CA, Ciubotaru M, Kamtekar S, Steitz TA, Schatz DG. Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis. Nature Structural & Molecular Biology. 16: 499-508. PMID 19396172 DOI: 10.1038/Nsmb.1593  0.522
2009 Liu M, Schatz DG. Balancing AID and DNA repair during somatic hypermutation. Trends in Immunology. 30: 173-81. PMID 19303358 DOI: 10.1016/J.It.2009.01.007  0.462
2009 Hesslein DG, Fretz JA, Xi Y, Nelson T, Zhou S, Lorenzo JA, Schatz DG, Horowitz MC. Ebf1-dependent control of the osteoblast and adipocyte lineages. Bone. 44: 537-46. PMID 19130908 DOI: 10.1016/J.Bone.2008.11.021  0.754
2009 Giblin W, Chatterji M, Westfield G, Masud T, Theisen B, Cheng HL, DeVido J, Alt FW, Ferguson DO, Schatz DG, Sekiguchi J. Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation. Blood. 113: 2965-75. PMID 19126872 DOI: 10.1182/Blood-2008-07-165167  0.592
2009 Strout MP, Schatz DG. Negative Regulation of Activation-Induced Cytidine Deaminase Protein Prevents Aberrant Somatic Hypermutation and Lymphomagenesis. Blood. 114: 94-94. DOI: 10.1182/Blood.V114.22.94.94  0.461
2008 Liu M, Duke JL, Richter DJ, Vinuesa CG, Goodnow CC, Kleinstein SH, Schatz DG. Two levels of protection for the B cell genome during somatic hypermutation. Nature. 451: 841-5. PMID 18273020 DOI: 10.1038/Nature06547  0.45
2008 Schatz DG, Oettinger MA, Baltimore D. Pillars article: the V(D)J recombination activating gene, RAG-1. 1989. Journal of Immunology (Baltimore, Md. : 1950). 180: 5-18. PMID 18096996  0.59
2008 Strout MP, Schatz DG. A Role for Small RNA Molecules during the DNA Repair Phase of Somatic Hypermutation Blood. 112: 785-785. DOI: 10.1182/Blood.V112.11.785.785  0.422
2007 Chatterji M, Unniraman S, McBride KM, Schatz DG. Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation. Journal of Immunology (Baltimore, Md. : 1950). 179: 5274-80. PMID 17911613 DOI: 10.4049/Jimmunol.179.8.5274  0.417
2007 Unniraman S, Schatz DG. Strand-biased spreading of mutations during somatic hypermutation. Science (New York, N.Y.). 317: 1227-30. PMID 17761884 DOI: 10.1126/Science.1145065  0.397
2007 Drejer-Teel AH, Fugmann SD, Schatz DG. The beyond 12/23 restriction is imposed at the nicking and pairing steps of DNA cleavage during V(D)J recombination. Molecular and Cellular Biology. 27: 6288-99. PMID 17636023 DOI: 10.1128/Mcb.00835-07  0.486
2007 Yang SY, Fugmann SD, Gramlich HS, Schatz DG. Activation-induced cytidine deaminase-mediated sequence diversification is transiently targeted to newly integrated DNA substrates. The Journal of Biological Chemistry. 282: 25308-13. PMID 17613522 DOI: 10.1074/Jbc.M704231200  0.789
2007 Yang SY, Schatz DG. Targeting of AID-mediated sequence diversification by cis-acting determinants. Advances in Immunology. 94: 109-25. PMID 17560273 DOI: 10.1016/S0065-2776(06)94004-8  0.552
2007 Schatz DG. DNA deaminases converge on adaptive immunity. Nature Immunology. 8: 551-3. PMID 17514205 DOI: 10.1038/Ni0607-551  0.307
2007 Schatz D, Ciubotaru M. Probing the structure of RAG protein‐DNA intermediates in V(D)J recombination The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A44-D  0.341
2006 Yang SY, Fugmann SD, Schatz DG. Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences. The Journal of Experimental Medicine. 203: 2919-28. PMID 17178919 DOI: 10.1084/Jem.20061835  0.56
2006 Odegard VH, Schatz DG. Targeting of somatic hypermutation. Nature Reviews. Immunology. 6: 573-83. PMID 16868548 DOI: 10.1038/Nri1896  0.796
2006 Inlay MA, Gao HH, Odegard VH, Lin T, Schatz DG, Xu Y. Roles of the Ig kappa light chain intronic and 3' enhancers in Igk somatic hypermutation. Journal of Immunology (Baltimore, Md. : 1950). 177: 1146-51. PMID 16818772 DOI: 10.4049/Jimmunol.177.2.1146  0.795
2006 Unniraman S, Schatz DG. AID and Igh switch region-Myc chromosomal translocations. Dna Repair. 5: 1259-64. PMID 16784901 DOI: 10.1016/J.Dnarep.2006.05.019  0.338
2006 Chatterji M, Tsai CL, Schatz DG. Mobilization of RAG-generated signal ends by transposition and insertion in vivo. Molecular and Cellular Biology. 26: 1558-68. PMID 16449665 DOI: 10.1128/Mcb.26.4.1558-1568.2006  0.589
2006 Hesslein DG, Yang SY, Schatz DG. Origins of peripheral B cells in IL-7 receptor-deficient mice. Molecular Immunology. 43: 326-34. PMID 16310046 DOI: 10.1016/J.Molimm.2005.02.010  0.786
2005 Shockett P, Schatz D. Inducible gene expression using an autoregulatory, tetracycline-controlled system Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 20.8. PMID 18228465 DOI: 10.1002/0471142727.Mb1614S60  0.39
2005 Schatz DG, Spanopoulou E. Biochemistry of V(D)J recombination. Current Topics in Microbiology and Immunology. 290: 49-85. PMID 16480039 DOI: 10.1007/3-540-26363-2_4  0.446
2005 Horowitz MC, Bothwell AL, Hesslein DG, Pflugh DL, Schatz DG. B cells and osteoblast and osteoclast development. Immunological Reviews. 208: 141-53. PMID 16313346 DOI: 10.1111/J.0105-2896.2005.00328.X  0.786
2005 Jones KR, Gewirtz DA, Yannone SM, Zhou S, Schatz DG, Valerie K, Povirk LF. Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein. Molecular Cancer Therapeutics. 4: 1541-7. PMID 16227403 DOI: 10.1158/1535-7163.Mct-05-0193  0.377
2005 Rush JS, Liu M, Odegard VH, Unniraman S, Schatz DG. Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 102: 13242-7. PMID 16141332 DOI: 10.1073/Pnas.0502779102  0.796
2005 Odegard VH, Kim ST, Anderson SM, Shlomchik MJ, Schatz DG. Histone modifications associated with somatic hypermutation. Immunity. 23: 101-10. PMID 16039583 DOI: 10.1016/J.Immuni.2005.05.007  0.772
2004 Horowitz MC, Xi Y, Pflugh DL, Hesslein DG, Schatz DG, Lorenzo JA, Bothwell AL. Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitors. Journal of Immunology (Baltimore, Md. : 1950). 173: 6583-91. PMID 15557148 DOI: 10.4049/Jimmunol.173.11.6583  0.789
2004 Schatz DG. Antigen receptor genes and the evolution of a recombinase. Seminars in Immunology. 16: 245-56. PMID 15522623 DOI: 10.1016/J.Smim.2004.08.004  0.428
2004 Unniraman S, Zhou S, Schatz DG. Identification of an AID-independent pathway for chromosomal translocations between the Igh switch region and Myc. Nature Immunology. 5: 1117-23. PMID 15489857 DOI: 10.1038/Ni1127  0.353
2004 Ciubotaru M, Schatz DG. Synapsis of recombination signal sequences located in cis and DNA underwinding in V(D)J recombination. Molecular and Cellular Biology. 24: 8727-44. PMID 15367690 DOI: 10.1128/Mcb.24.19.8727-8744.2004  0.385
2004 Johnson K, Pflugh DL, Yu D, Hesslein DG, Lin KI, Bothwell AL, Thomas-Tikhonenko A, Schatz DG, Calame K. B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5. Nature Immunology. 5: 853-61. PMID 15258579 DOI: 10.1038/Ni1099  0.779
2004 Chatterji M, Tsai CL, Schatz DG. New concepts in the regulation of an ancient reaction: transposition by RAG1/RAG2. Immunological Reviews. 200: 261-71. PMID 15242411 DOI: 10.1111/J.0105-2896.2004.00167.X  0.62
2004 Schatz DG. V(D)J recombination. Immunological Reviews. 200: 5-11. PMID 15242391 DOI: 10.1111/J.0105-2896.2004.00173.X  0.342
2004 Hubank M, Bryntesson F, Regan J, Schatz DG. Cloning of apoptosis-related genes by representational difference analysis of cDNA. Methods in Molecular Biology (Clifton, N.J.). 282: 255-73. PMID 15105570 DOI: 10.1385/1-59259-812-9:255  0.371
2004 Repasky JA, Corbett E, Boboila C, Schatz DG. Mutational analysis of terminal deoxynucleotidyltransferase-mediated N-nucleotide addition in V(D)J recombination. Journal of Immunology (Baltimore, Md. : 1950). 172: 5478-88. PMID 15100289 DOI: 10.4049/Jimmunol.172.9.5478  0.745
2004 Schatz DG, Baltimore D. Uncovering the V(D)J recombinase. Cell. 116: S103-6, 2 p followin. PMID 15055595 DOI: 10.1016/S0092-8674(04)00042-X  0.668
2004 Rush JS, Fugmann SD, Schatz DG. Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination. International Immunology. 16: 549-57. PMID 15039385 DOI: 10.1093/Intimm/Dxh057  0.402
2004 Fugmann SD, Rush JS, Schatz DG. Non-redundancy of cytidine deaminases in class switch recombination. European Journal of Immunology. 34: 844-9. PMID 14991614 DOI: 10.1002/Eji.200324418  0.445
2004 Zheng WP, Zhao Q, Zhao X, Li B, Hubank M, Schatz DG, Flavell RA. Up-regulation of Hlx in immature Th cells induces IFN-gamma expression. Journal of Immunology (Baltimore, Md. : 1950). 172: 114-22. PMID 14688316 DOI: 10.4049/Jimmunol.172.1.114  0.318
2004 Shockett PE, Zhou S, Hong X, Schatz DG. Partial reconstitution of V(D)J rearrangement and lymphocyte development in RAG-deficient mice expressing inducible, tetracycline-regulated RAG transgenes. Molecular Immunology. 40: 813-29. PMID 14687938 DOI: 10.1016/J.Molimm.2003.09.009  0.414
2003 Tsai CL, Chatterji M, Schatz DG. DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase. Nucleic Acids Research. 31: 6180-90. PMID 14576304 DOI: 10.1093/Nar/Gkg819  0.603
2003 Lee AI, Fugmann SD, Cowell LG, Ptaszek LM, Kelsoe G, Schatz DG. A functional analysis of the spacer of V(D)J recombination signal sequences. Plos Biology. 1: E1. PMID 14551903 DOI: 10.1371/Journal.Pbio.0000001  0.65
2003 Fugmann SD, Schatz DG. RNA AIDS DNA. Nature Immunology. 4: 429-30. PMID 12719733 DOI: 10.1038/Ni0503-429  0.361
2003 Tsai CL, Schatz DG. Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2. The Embo Journal. 22: 1922-30. PMID 12682024 DOI: 10.1093/Emboj/Cdg185  0.614
2003 Rooney S, Alt FW, Lombard D, Whitlow S, Eckersdorff M, Fleming J, Fugmann S, Ferguson DO, Schatz DG, Sekiguchi J. Defective DNA repair and increased genomic instability in Artemis-deficient murine cells. The Journal of Experimental Medicine. 197: 553-65. PMID 12615897 DOI: 10.1084/Jem.20021891  0.558
2003 Jung D, Bassing CH, Fugmann SD, Cheng HL, Schatz DG, Alt FW. Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. Immunity. 18: 65-74. PMID 12530976 DOI: 10.1016/S1074-7613(02)00507-1  0.57
2003 Hesslein DG, Pflugh DL, Chowdhury D, Bothwell AL, Sen R, Schatz DG. Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments. Genes & Development. 17: 37-42. PMID 12514097 DOI: 10.1101/Gad.1031403  0.814
2003 Ciubotaru M, Ptaszek LM, Baker GA, Baker SN, Bright FV, Schatz DG. RAG1-DNA binding in V(D)J recombination. Specificity and DNA-induced conformational changes revealed by fluorescence and CD spectroscopy. The Journal of Biological Chemistry. 278: 5584-96. PMID 12488446 DOI: 10.1074/Jbc.M209758200  0.401
2003 Bottomly K, Cresswell P, Flavell RA, Ghosh S, Pober JS, Schatz DG. Charles A. Janeway, Jr. (1943-2003) Cell. 113: 433-434. DOI: 10.1016/S1074-7613(03)00123-7  0.52
2003 Bottomly K, Cresswell P, Flavell RA, Ghosh S, Pober JS, Schatz DG. Charles A. Janeway, Jr. (1943-2003) Immunity. 18: 591-592. DOI: 10.1016/S1074-7613(03)00123-7  0.383
2002 Tsai CL, Drejer AH, Schatz DG. Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination. Genes & Development. 16: 1934-49. PMID 12154124 DOI: 10.1101/Gad.984502  0.612
2002 Papavasiliou FN, Schatz DG. The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process. The Journal of Experimental Medicine. 195: 1193-8. PMID 11994424 DOI: 10.1084/Jem.20011858  0.476
2002 Papavasiliou FN, Schatz DG. Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity. Cell. 109: S35-44. PMID 11983151 DOI: 10.1016/S0092-8674(02)00706-7  0.4
2002 Fugmann SD, Schatz DG. Immunology. One AID to unite them all. Science (New York, N.Y.). 295: 1244-5. PMID 11847327 DOI: 10.1126/Science.1070023  0.404
2001 Fugmann SD, Schatz DG. Identification of basic residues in RAG2 critical for DNA binding by the RAG1-RAG2 complex. Molecular Cell. 8: 899-910. PMID 11684024 DOI: 10.1016/S1097-2765(01)00352-5  0.44
2001 Hesslein DG, Fields PE, Schatz DG. Location, location, location: the cell biology of immunoglobulin allelic control. Nature Immunology. 2: 825-6. PMID 11526394 DOI: 10.1038/Ni0901-825  0.763
2001 Hesslein DG, Schatz DG. Factors and forces controlling V(D)J recombination. Advances in Immunology. 78: 169-232. PMID 11432204 DOI: 10.1016/S0065-2776(01)78004-2  0.759
2000 Papavasiliou FN, Schatz DG. Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes. Nature. 408: 216-21. PMID 11089977 DOI: 10.1038/35041599  0.484
2000 Livak F, Burtrum DB, Rowen L, Schatz DG, Petrie HT. Genetic modulation of T cell receptor gene segment usage during somatic recombination. The Journal of Experimental Medicine. 192: 1191-6. PMID 11034609 DOI: 10.1084/Jem.192.8.1191  0.401
2000 Fugmann SD, Lee AI, Shockett PE, Villey IJ, Schatz DG. The RAG proteins and V(D)J recombination: complexes, ends, and transposition. Annual Review of Immunology. 18: 495-527. PMID 10837067 DOI: 10.1146/Annurev.Immunol.18.1.495  0.616
2000 Tevelev A, Schatz DG. Intermolecular V(D)J recombination. The Journal of Biological Chemistry. 275: 8341-8. PMID 10722664 DOI: 10.1074/Jbc.275.12.8341  0.352
2000 Fugmann SD, Villey IJ, Ptaszek LM, Schatz DG. Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex. Molecular Cell. 5: 97-107. PMID 10678172 DOI: 10.1016/S1097-2765(00)80406-2  0.365
1999 Schatz DG. Transposition mediated by RAG1 and RAG2 and the evolution of the adaptive immune system. Immunologic Research. 19: 169-82. PMID 10493171 DOI: 10.1007/Bf02786485  0.406
1999 Schatz DG. Developing B-cell theories. Nature. 400: 614-5, 617. PMID 10458155 DOI: 10.1038/23134  0.317
1999 Rodgers KK, Villey IJ, Ptaszek L, Corbett E, Schatz DG, Coleman JE. A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2. Nucleic Acids Research. 27: 2938-46. PMID 10390537 DOI: 10.1093/Nar/27.14.2938  0.387
1999 Hubank M, Schatz DG. cDNA representational difference analysis: a sensitive and flexible method for identification of differentially expressed genes. Methods in Enzymology. 303: 325-49. PMID 10349653 DOI: 10.1016/S0076-6879(99)03021-9  0.329
1999 Shockett PE, Schatz DG. DNA hairpin opening mediated by the RAG1 and RAG2 proteins. Molecular and Cellular Biology. 19: 4159-66. PMID 10330156 DOI: 10.1128/Mcb.19.6.4159  0.417
1999 Chun J, Schatz DG. Developmental neurobiology: Alternative ends for a familiar story? Current Biology : Cb. 9: R251-3. PMID 10209111 DOI: 10.1016/S0960-9822(99)80156-0  0.583
1999 Eastman QM, Villey IJ, Schatz DG. Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking. Molecular and Cellular Biology. 19: 3788-97. PMID 10207102 DOI: 10.1128/Mcb.19.5.3788  0.395
1999 Chun J, Schatz DG. Rearranging views on neurogenesis: neuronal death in the absence of DNA end-joining proteins. Neuron. 22: 7-10. PMID 10027282 DOI: 10.1016/S0896-6273(00)80671-6  0.506
1998 Agrawal A, Eastman QM, Schatz DG. Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature. 394: 744-51. PMID 9723614 DOI: 10.1038/29457  0.468
1998 Livák F, Schatz DG. Alternative splicing of rearranged T cell receptor delta sequences to the constant region of the alpha locus. Proceedings of the National Academy of Sciences of the United States of America. 95: 5694-9. PMID 9576946 DOI: 10.1073/Pnas.95.10.5694  0.399
1997 Eastman QM, Schatz DG. Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage. Nucleic Acids Research. 25: 4370-8. PMID 9336470 DOI: 10.1093/Nar/25.21.4370  0.328
1997 Leu TM, Eastman QM, Schatz DG. Coding joint formation in a cell-free V(D)J recombination system. Immunity. 7: 303-14. PMID 9285414 DOI: 10.1016/S1074-7613(00)80532-4  0.384
1997 McMahan CJ, Difilippantonio MJ, Rao N, Spanopoulou E, Schatz DG. A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity. Molecular and Cellular Biology. 17: 4544-52. PMID 9234712 DOI: 10.1128/Mcb.17.8.4544  0.703
1997 Schatz DG. V(D)J recombination moves in vitro. Seminars in Immunology. 9: 149-59. PMID 9200326 DOI: 10.1006/Smim.1997.0068  0.426
1997 Livák F, Schatz DG. Identification of V(D)J recombination coding end intermediates in normal thymocytes. Journal of Molecular Biology. 267: 1-9. PMID 9096202 DOI: 10.1006/Jmbi.1996.0834  0.414
1997 Agrawal A, Schatz DG. RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination. Cell. 89: 43-53. PMID 9094713 DOI: 10.1016/S0092-8674(00)80181-6  0.389
1997 Shockett P, Schatz D. Switching on gene expression. Nature Biotechnology. 15: 219-221. PMID 9062915 DOI: 10.1038/Nbt0397-219  0.312
1996 Han S, Zheng B, Schatz DG, Spanopoulou E, Kelsoe G. Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells. Science (New York, N.Y.). 274: 2094-7. PMID 8953043 DOI: 10.1126/Science.274.5295.2094  0.454
1996 Difilippantonio MJ, McMahan CJ, Eastman QM, Spanopoulou E, Schatz DG. RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination. Cell. 87: 253-62. PMID 8861909 DOI: 10.1016/S0092-8674(00)81343-4  0.679
1996 Schatz DG, Leu TM. rag-1 and rag-2: biochemistry and protein interactions. Current Topics in Microbiology and Immunology. 217: 11-29. PMID 8787615 DOI: 10.1007/978-3-642-50140-1_2  0.434
1996 Livák F, Welsh SC, Guidos CJ, Crispe IN, Danska JS, Schatz DG. Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice. The Journal of Experimental Medicine. 184: 419-28. PMID 8760795 DOI: 10.1084/Jem.184.2.419  0.379
1996 Rodgers KK, Bu Z, Fleming KG, Schatz DG, Engelman DM, Coleman JE. A zinc-binding domain involved in the dimerization of RAG1. Journal of Molecular Biology. 260: 70-84. PMID 8676393 DOI: 10.1006/Jmbi.1996.0382  0.344
1996 Grawunder U, Schatz DG, Leu TM, Rolink A, Melchers F. The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression. The Journal of Experimental Medicine. 183: 1731-7. PMID 8666930 DOI: 10.1084/Jem.183.4.1731  0.413
1996 Shockett PE, Schatz DG. Diverse strategies for tetracycline-regulated inducible gene expression. Proceedings of the National Academy of Sciences of the United States of America. 93: 5173-6. PMID 8643548 DOI: 10.1073/Pnas.93.11.5173  0.42
1996 Hoffman ES, Passoni L, Crompton T, Leu TM, Schatz DG, Koff A, Owen MJ, Hayday AC. Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo. Genes & Development. 10: 948-62. PMID 8608942 DOI: 10.1101/Gad.10.8.948  0.382
1996 Eastman QM, Leu TM, Schatz DG. Initiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature. 380: 85-8. PMID 8598914 DOI: 10.1038/380085A0  0.412
1996 Livak F, Schatz DG. T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells. Molecular and Cellular Biology. 16: 609-18. PMID 8552089 DOI: 10.1128/Mcb.16.2.609  0.396
1995 Livak F, Petrie HT, Crispe IN, Schatz DG. In-frame TCR delta gene rearrangements play a critical role in the alpha beta/gamma delta T cell lineage decision. Immunity. 2: 617-27. PMID 7796295 DOI: 10.1016/1074-7613(95)90006-3  0.308
1995 Shockett P, Difilippantonio M, Hellman N, Schatz DG. A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 6522-6. PMID 7604026 DOI: 10.1073/Pnas.92.14.6522  0.685
1995 Grawunder U, Leu TM, Schatz DG, Werner A, Rolink AG, Melchers F, Winkler TH. Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement. Immunity. 3: 601-8. PMID 7584150 DOI: 10.1016/1074-7613(95)90131-0  0.426
1995 Leu TM, Schatz DG. rag-1 and rag-2 are components of a high-molecular-weight complex, and association of rag-2 with this complex is rag-1 dependent. Molecular and Cellular Biology. 15: 5657-70. PMID 7565717 DOI: 10.1128/Mcb.15.10.5657  0.327
1994 Hubank M, Schatz DG. Identifying differences in mRNA expression by representational difference analysis of cDNA. Nucleic Acids Research. 22: 5640-8. PMID 7838717 DOI: 10.1093/Nar/22.25.5640  0.422
1992 Oettinger MA, Stanger B, Schatz DG, Glaser T, Call K, Housman D, Baltimore D. The recombination activating genes, RAG 1 and RAG 2, are on chromosome 11p in humans and chromosome 2p in mice. Immunogenetics. 35: 97-101. PMID 1735560 DOI: 10.1007/Bf00189518  0.592
1992 Schatz DG, Oettinger MA, Schlissel MS. V(D)J recombination: molecular biology and regulation. Annual Review of Immunology. 10: 359-83. PMID 1590991 DOI: 10.1146/Annurev.Iy.10.040192.002043  0.416
1991 Carlson LM, Oettinger MA, Schatz DG, Masteller EL, Hurley EA, McCormack WT, Baltimore D, Thompson CB. Selective expression of RAG-2 in chicken B cells undergoing immunoglobulin gene conversion. Cell. 64: 201-8. PMID 1986866 DOI: 10.1016/0092-8674(91)90221-J  0.676
1991 Chun JJ, Schatz DG, Oettinger MA, Jaenisch R, Baltimore D. The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Cell. 64: 189-200. PMID 1986864 DOI: 10.1016/0092-8674(91)90220-S  0.618
1991 Turka LA, Schatz DG, Oettinger MA, Chun JJ, Gorka C, Lee K, McCormack WT, Thompson CB. Thymocyte expression of RAG-1 and RAG-2: termination by T cell receptor cross-linking. Science (New York, N.Y.). 253: 778-81. PMID 1831564 DOI: 10.1126/Science.1831564  0.311
1991 Hendrickson EA, Qin XQ, Bump EA, Schatz DG, Oettinger M, Weaver DT. A link between double-strand break-related repair and V(D)J recombination: the scid mutation. Proceedings of the National Academy of Sciences of the United States of America. 88: 4061-5. PMID 1709732 DOI: 10.1073/Pnas.88.10.4061  0.422
1990 Oettinger MA, Schatz DG, Gorka C, Baltimore D. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science (New York, N.Y.). 248: 1517-23. PMID 2360047 DOI: 10.1126/Science.2360047  0.677
1989 Schatz DG, Oettinger MA, Baltimore D. The V(D)J recombination activating gene, RAG-1. Cell. 59: 1035-48. PMID 2598259 DOI: 10.1016/0092-8674(89)90760-5  0.647
1988 Schatz DG, Baltimore D. Stable expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts. Cell. 53: 107-15. PMID 3349523 DOI: 10.1016/0092-8674(88)90492-8  0.66
1988 Hendrickson EA, Schatz DG, Weaver DT. The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement. Genes & Development. 2: 817-29. PMID 3145241 DOI: 10.1101/Gad.2.7.817  0.497
1987 Landau NR, Schatz DG, Rosa M, Baltimore D. Increased frequency of N-region insertion in a murine pre-B-cell line infected with a terminal deoxynucleotidyl transferase retroviral expression vector. Molecular and Cellular Biology. 7: 3237-43. PMID 3118194 DOI: 10.1128/Mcb.7.9.3237  0.637
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