Loren Dean Williams, PhD - Publications

School of Chemistry & Biochemistry Georgia Institute of Technology, Atlanta, GA 
DNA, intercalators, crystallography, RNA, ribosome, evolution

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bowman JC, Petrov AS, Frenkel-Pinter M, Penev PI, Williams LD. Root of the Tree: The Significance, Evolution, and Origins of the Ribosome. Chemical Reviews. PMID 32374986 DOI: 10.1021/acs.chemrev.9b00742  0.68
2019 Frenkel-Pinter M, Haynes JW, C M, Petrov AS, Burcar BT, Krishnamurthy R, Hud NV, Leman LJ, Williams LD. Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31358633 DOI: 10.1073/pnas.1904849116  1
2019 Mestre-Fos S, Penev PI, Suttapitugsakul S, Ito C, Petrov AS, Wartell RM, Wu R, Williams LD. G-Quadruplexes in Human Ribosomal RNA. Journal of Molecular Biology. PMID 30885721 DOI: 10.1016/j.jmb.2019.03.010  0.68
2018 Runnels CM, Lanier KA, Williams JK, Bowman JC, Petrov AS, Hud NV, Williams LD. Folding, Assembly, and Persistence: The Essential Nature and Origins of Biopolymers. Journal of Molecular Evolution. PMID 30456440 DOI: 10.1007/s00239-018-9876-2  1
2018 Bray MS, Lenz TK, Haynes JW, Bowman JC, Petrov AS, Reddi AR, Hud NV, Williams LD, Glass JB. Multiple prebiotic metals mediate translation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30413624 DOI: 10.1073/pnas.1803636115  1
2018 Kovacs NA, Penev PI, Venapally A, Petrov AS, Williams LD. Circular Permutation Obscures Universality of a Ribosomal Protein. Journal of Molecular Evolution. PMID 30306205 DOI: 10.1007/s00239-018-9869-1  0.68
2018 Bernier CR, Petrov AS, Kovacs NA, Penev P, Williams LD. Translation: The Universal Structural Core of Life. Molecular Biology and Evolution. PMID 29788252 DOI: 10.1093/molbev/msy101  0.68
2017 Gómez Ramos LM, Degtyareva NN, Kovacs NA, Holguin SY, Jiang L, Petrov AS, Biesiada M, Hu MY, Purzycka KJ, Arya DP, Williams LD. Eukaryotic Ribosomal Expansion Segments as Antimicrobial Targets. Biochemistry. PMID 28895721 DOI: 10.1021/acs.biochem.7b00703  0.68
2017 Lanier KA, Petrov AS, Williams LD. The Central Symbiosis of Molecular Biology: Molecules in Mutualism. Journal of Molecular Evolution. PMID 28785970 DOI: 10.1007/s00239-017-9804-x  1
2017 Lanier KA, Roy P, Schneider DM, Williams LD. Ancestral Interactions of Ribosomal RNA and Ribosomal Proteins. Biophysical Journal. PMID 28506527 DOI: 10.1016/j.bpj.2017.04.007  1
2017 Okafor CD, Lanier KA, Petrov AS, Athavale SS, Bowman JC, Hud NV, Williams LD. Iron mediates catalysis of nucleic acid processing enzymes: support for Fe(II) as a cofactor before the great oxidation event. Nucleic Acids Research. PMID 28334877 DOI: 10.1093/nar/gkx171  1
2017 Jones BL, Walker C, Azizi B, Tolbert L, Williams LD, Snell TW. Conservation of estrogen receptor function in invertebrate reproduction. Bmc Evolutionary Biology. 17: 65. PMID 28259146 DOI: 10.1186/s12862-017-0909-z  0.36
2017 Lanier KA, Williams LD. The Origin of Life: Models and Data. Journal of Molecular Evolution. PMID 28243688 DOI: 10.1007/s00239-017-9783-y  1
2017 Kovacs NA, Petrov AS, Lanier KA, Dean Williams L. Frozen in Time: The History of Proteins. Molecular Biology and Evolution. PMID 28201543 DOI: 10.1093/molbev/msx086  0.64
2016 Fang PY, Gómez Ramos LM, Holguin SY, Hsiao C, Bowman JC, Yang HW, Williams LD. Functional RNAs: combined assembly and packaging in VLPs. Nucleic Acids Research. PMID 27903913 DOI: 10.1093/nar/gkw1154  1
2016 Lanier KA, Athavale SS, Petrov AS, Wartell RM, Williams LD. Imprint of Ancient Evolution on rRNA Folding. Biochemistry. PMID 27428664 DOI: 10.1021/acs.biochem.6b00168  1
2016 Gulen B, Petrov AS, Okafor CD, Vander Wood D, O'Neill EB, Hud NV, Williams LD. Ribosomal small subunit domains radiate from a central core. Scientific Reports. 6: 20885. PMID 26876483 DOI: 10.1038/srep20885  1
2016 Komeda S, Qu Y, Mangrum JB, Hegmans A, Williams LD, Farrell NP. The phosphate clamp as recognition motif in platinum-DNA interactions Inorganica Chimica Acta. DOI: 10.1016/j.ica.2016.04.052  1
2015 Petrov AS, Gulen B, Norris AM, Kovacs NA, Bernier CR, Lanier KA, Fox GE, Harvey SC, Wartell RM, Hud NV, Williams LD. History of the ribosome and the origin of translation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621738 DOI: 10.1073/pnas.1509761112  1
2015 Petrov AS, Williams LD. The ancient heart of the ribosomal large subunit: a response to Caetano-Anolles. Journal of Molecular Evolution. 80: 166-70. PMID 25877522 DOI: 10.1007/s00239-015-9678-8  1
2015 Bowman JC, Hud NV, Williams LD. The ribosome challenge to the RNA world. Journal of Molecular Evolution. 80: 143-61. PMID 25739364 DOI: 10.1007/s00239-015-9669-9  1
2015 Fox GE, Paci M, Tran Q, Petrov AS, Williams LD. Ribosome dynamics and the evolutionary history of ribosomes Proceedings of Spie - the International Society For Optical Engineering. 9606. DOI: 10.1117/12.2187098  1
2014 Harris LA, Williams LD, Koudelka GB. Specific minor groove solvation is a crucial determinant of DNA binding site recognition. Nucleic Acids Research. 42: 14053-9. PMID 25429976 DOI: 10.1093/nar/gku1259  1
2014 Bernier CR, Petrov AS, Waterbury CC, Jett J, Li F, Freil LE, Xiong X, Wang L, Migliozzi BL, Hershkovits E, Xue Y, Hsiao C, Bowman JC, Harvey SC, Grover MA, ... ... Williams LD, et al. RiboVision suite for visualization and analysis of ribosomes. Faraday Discussions. 169: 195-207. PMID 25340471 DOI: 10.1039/c3fd00126a  1
2014 Petrov AS, Bernier CR, Hsiao C, Norris AM, Kovacs NA, Waterbury CC, Stepanov VG, Harvey SC, Fox GE, Wartell RM, Hud NV, Williams LD. Evolution of the ribosome at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 111: 10251-6. PMID 24982194 DOI: 10.1073/pnas.1407205111  1
2014 Petrov AS, Bernier CR, Gulen B, Waterbury CC, Hershkovits E, Hsiao C, Harvey SC, Hud NV, Fox GE, Wartell RM, Williams LD. Secondary structures of rRNAs from all three domains of life. Plos One. 9: e88222. PMID 24505437 DOI: 10.1371/journal.pone.0088222  1
2014 Ma Z, Chen W, Johnson MC, Schmidt-Krey I, Williams L, Schuster GB. Modular-DNA programmed molecular construction of "Fixed" of 2D and 3D-Au nanoparticle arrays Chemistry of Materials. 26: 5499-5505. DOI: 10.1021/cm501459a  1
2013 Jones BL, VanLoozen J, Kim MH, Miles SJ, Dunham CM, Williams LD, Snell TW. Stress granules form in Brachionus manjavacas (Rotifera) in response to a variety of stressors. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 166: 375-84. PMID 23856158 DOI: 10.1016/j.cbpa.2013.07.009  1
2013 Petrov AS, Bernier CR, Hershkovits E, Xue Y, Waterbury CC, Hsiao C, Stepanov VG, Gaucher EA, Grover MA, Harvey SC, Hud NV, Wartell RM, Fox GE, Williams LD. Secondary structure and domain architecture of the 23S and 5S rRNAs. Nucleic Acids Research. 41: 7522-35. PMID 23771137 DOI: 10.1093/nar/gkt513  1
2013 Hsiao C, Chou IC, Okafor CD, Bowman JC, O'Neill EB, Athavale SS, Petrov AS, Hud NV, Wartell RM, Harvey SC, Williams LD. RNA with iron(II) as a cofactor catalyses electron transfer. Nature Chemistry. 5: 525-8. PMID 23695635 DOI: 10.1038/nchem.1649  1
2013 Hud NV, Cafferty BJ, Krishnamurthy R, Williams LD. The origin of RNA and "my grandfather's axe". Chemistry & Biology. 20: 466-74. PMID 23601635 DOI: 10.1016/j.chembiol.2013.03.012  1
2013 Hsiao C, Lenz TK, Peters JK, Fang PY, Schneider DM, Anderson EJ, Preeprem T, Bowman JC, O'Neill EB, Lie L, Athavale SS, Gossett JJ, Trippe C, Murray J, Petrov AS, ... ... Williams LD, et al. Molecular paleontology: a biochemical model of the ancestral ribosome. Nucleic Acids Research. 41: 3373-85. PMID 23355613 DOI: 10.1093/nar/gkt023  1
2013 Athavale SS, Gossett JJ, Bowman JC, Hud NV, Williams LD, Harvey SC. In vitro secondary structure of the genomic RNA of satellite tobacco mosaic virus. Plos One. 8: e54384. PMID 23349871 DOI: 10.1371/journal.pone.0054384  0.76
2013 Harris LA, Watkins D, Williams LD, Koudelka GB. Indirect readout of DNA sequence by p22 repressor: roles of DNA and protein functional groups in modulating DNA conformation. Journal of Molecular Biology. 425: 133-43. PMID 23085222 DOI: 10.1016/j.jmb.2012.10.008  1
2012 Peters JW, Williams LD. The origin of life: look up and look down. Astrobiology. 12: 1087-92. PMID 23088411 DOI: 10.1089/ast.2012.0818  1
2012 Bowman JC, Azizi B, Lenz TK, Roy P, Williams LD. Preparation of long templates for RNA in vitro transcription by recursive PCR. Methods in Molecular Biology (Clifton, N.J.). 941: 19-41. PMID 23065551 DOI: 10.1007/978-1-62703-113-4_3  1
2012 Petrov AS, Bernier CR, Hsiao C, Okafor CD, Tannenbaum E, Stern J, Gaucher E, Schneider D, Hud NV, Harvey SC, Williams LD. RNA-magnesium-protein interactions in large ribosomal subunit. The Journal of Physical Chemistry. B. 116: 8113-20. PMID 22712611 DOI: 10.1021/jp304723w  0.76
2012 Athavale SS, Petrov AS, Hsiao C, Watkins D, Prickett CD, Gossett JJ, Lie L, Bowman JC, O'Neill E, Bernier CR, Hud NV, Wartell RM, Harvey SC, Williams LD. RNA folding and catalysis mediated by iron (II). Plos One. 7: e38024. PMID 22701543 DOI: 10.1371/journal.pone.0038024  1
2012 Bowman JC, Lenz TK, Hud NV, Williams LD. Cations in charge: magnesium ions in RNA folding and catalysis. Current Opinion in Structural Biology. 22: 262-72. PMID 22595008 DOI: 10.1016/j.sbi.2012.04.006  1
2012 Engelhart AE, Cafferty BJ, Okafor CD, Chen MC, Williams LD, Lynn DG, Hud NV. Nonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR. Chembiochem : a European Journal of Chemical Biology. 13: 1121-4. PMID 22556064 DOI: 10.1002/cbic.201200167  1
2012 Athavale SS, Gossett JJ, Hsiao C, Bowman JC, O'Neill E, Hershkovitz E, Preeprem T, Hud NV, Wartell RM, Harvey SC, Williams LD. Domain III of the T. thermophilus 23S rRNA folds independently to a near-native state. Rna (New York, N.Y.). 18: 752-8. PMID 22334759 DOI: 10.1261/rna.030692.111  1
2012 Maehigashi T, Hsiao C, Woods KK, Moulaei T, Hud NV, Williams LD. B-DNA structure is intrinsically polymorphic: even at the level of base pair positions. Nucleic Acids Research. 40: 3714-22. PMID 22180536 DOI: 10.1093/nar/gkr1168  1
2011 Buckley R, Enekwa CD, Williams LD, Hud NV. Molecular recognition of Watson-Crick-like purine-purine base pairs. Chembiochem : a European Journal of Chemical Biology. 12: 2155-8. PMID 21805554 DOI: 10.1002/cbic.201100375  1
2011 Petrov AS, Bowman JC, Harvey SC, Williams LD. Bidentate RNA-magnesium clamps: on the origin of the special role of magnesium in RNA folding. Rna (New York, N.Y.). 17: 291-7. PMID 21173199 DOI: 10.1261/rna.2390311  1
2011 Komeda S, Moulaei T, Chikuma M, Odani A, Kipping R, Farrell NP, Williams LD. The phosphate clamp: a small and independent motif for nucleic acid backbone recognition. Nucleic Acids Research. 39: 325-36. PMID 20736180 DOI: 10.1093/nar/gkq723  1
2011 Watkins D, Harris LA, Koudelka GB, Williams LD. Protein: Feeling the groove of DNA Acs Symposium Series. 1082: 133-145. DOI: 10.1021/bk-2011-1082.ch008  1
2010 Mohan S, Hsiao C, Bowman JC, Wartell R, Williams LD. RNA tetraloop folding reveals tension between backbone restraints and molecular interactions. Journal of the American Chemical Society. 132: 12679-89. PMID 20726568 DOI: 10.1021/ja104387k  1
2010 Watkins D, Mohan S, Koudelka GB, Williams LD. Sequence recognition of DNA by protein-induced conformational transitions. Journal of Molecular Biology. 396: 1145-64. PMID 20053356 DOI: 10.1016/j.jmb.2009.12.050  1
2010 Watkins D, Moulaei T, Komeda S, Williams LD. Application of anomalous diffraction methods to the study of DNA and DNA-complexes. Methods in Molecular Biology (Clifton, N.J.). 613: 133-52. PMID 19997882 DOI: 10.1007/978-1-60327-418-0_9  1
2009 Mohan S, Hsiao C, VanDeusen H, Gallagher R, Krohn E, Kalahar B, Wartell RM, Williams LD. Mechanism of RNA double helix-propagation at atomic resolution. The Journal of Physical Chemistry. B. 113: 2614-23. PMID 19708202 DOI: 10.1021/jp8039884  1
2009 Hsiao C, Mohan S, Kalahar BK, Williams LD. Peeling the onion: ribosomes are ancient molecular fossils. Molecular Biology and Evolution. 26: 2415-25. PMID 19628620 DOI: 10.1093/molbev/msp163  1
2009 Hsiao C, Williams LD. A recurrent magnesium-binding motif provides a framework for the ribosomal peptidyl transferase center. Nucleic Acids Research. 37: 3134-42. PMID 19279186 DOI: 10.1093/nar/gkp119  1
2009 Apostolico A, Ciriello G, Guerra C, Heitsch CE, Hsiao C, Williams LD. Finding 3D motifs in ribosomal RNA structures. Nucleic Acids Research. 37: e29. PMID 19158187 DOI: 10.1093/nar/gkn1044  1
2008 Watkins D, Hsiao C, Woods KK, Koudelka GB, Williams LD. P22 c2 repressor-operator complex: mechanisms of direct and indirect readout. Biochemistry. 47: 2325-38. PMID 18237194 DOI: 10.1021/bi701826f  1
2008 Richardson JS, Schneider B, Murray LW, Kapral GJ, Immormino RM, Headd JJ, Richardson DC, Ham D, Hershkovits E, Williams LD, Keating KS, Pyle AM, Micallef D, Westbrook J, Berman HM, et al. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). Rna (New York, N.Y.). 14: 465-81. PMID 18192612 DOI: 10.1261/rna.657708  1
2006 Komeda S, Moulaei T, Woods KK, Chikuma M, Farrell NP, Williams LD. A third mode of DNA binding: Phosphate clamps by a polynuclear platinum complex. Journal of the American Chemical Society. 128: 16092-103. PMID 17165762 DOI: 10.1021/ja062851y  1
2006 Gold B, Marky LM, Stone MP, Williams LD. A review of the role of the sequence-dependent electrostatic landscape in DNA alkylation patterns. Chemical Research in Toxicology. 19: 1402-14. PMID 17112226 DOI: 10.1021/tx060127n  1
2006 Hershkovitz E, Sapiro G, Tannenbaum A, Williams LD. Statistical analysis of RNA backbone. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 3: 33-46. PMID 17048391 DOI: 10.1109/TCBB.2006.13  1
2006 Hsiao C, Mohan S, Hershkovitz E, Tannenbaum A, Williams LD. Single nucleotide RNA choreography. Nucleic Acids Research. 34: 1481-91. PMID 16531589 DOI: 10.1093/nar/gkj500  1
2005 Moulaei T, Maehigashi T, Lountos GT, Komeda S, Watkins D, Stone MP, Marky LA, Li JS, Gold B, Williams LD. Structure of B-DNA with cations tethered in the major groove. Biochemistry. 44: 7458-68. PMID 15895989 DOI: 10.1021/bi050128z  1
2005 Williams LD. Between objectivity and whim: Nucleic acid structural biology Topics in Current Chemistry. 253: 77-88. DOI: 10.1007/b100443  1
2004 Woods KK, Maehigashi T, Howerton SB, Sines CC, Tannenbaum S, Williams LD. High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2. Journal of the American Chemical Society. 126: 15330-1. PMID 15563130 DOI: 10.1021/ja045207x  1
2003 Hershkovitz E, Tannenbaum E, Howerton SB, Sheth A, Tannenbaum A, Williams LD. Automated identification of RNA conformational motifs: theory and application to the HM LSU 23S rRNA. Nucleic Acids Research. 31: 6249-57. PMID 14576313 DOI: 10.1093/nar/gkg835  1
2003 Razskazovskiy Y, Debije MG, Howerton SB, Williams LD, Bernhard WA. Strand breaks in X-irradiated crystalline DNA: alternating CG oligomers. Radiation Research. 160: 334-9. PMID 12926992 DOI: 10.1667/RR3051  1
2003 Howerton SB, Nagpal A, Williams LD. Surprising roles of electrostatic interactions in DNA-ligand complexes. Biopolymers. 69: 87-99. PMID 12717724 DOI: 10.1002/bip.10319  1
2003 Woods KK, Lan T, McLaughlin LW, Williams LD. The role of minor groove functional groups in DNA hydration. Nucleic Acids Research. 31: 1536-40. PMID 12595562 DOI: 10.1093/nar/gkg240  1
2003 Reynisson J, Schuster GB, Howerton SB, Williams LD, Barnett RN, Cleveland CL, Landman U, Harrit N, Chaires JB. Intercalation of trioxatriangulenium ion in DNA: binding, electron transfer, x-ray crystallography, and electronic structure. Journal of the American Chemical Society. 125: 2072-83. PMID 12590535 DOI: 10.1021/ja0211196  0.68
2002 Hamelberg D, Williams LD, Wilson WD. Effect of a neutralized phosphate backbone on the minor groove of B-DNA: molecular dynamics simulation studies. Nucleic Acids Research. 30: 3615-23. PMID 12177304  1
2001 Howerton SB, Sines CC, VanDerveer D, Williams LD. Locating monovalent cations in the grooves of B-DNA. Biochemistry. 40: 10023-31. PMID 11513580 DOI: 10.1021/bi010391+  1
2001 Peek ME, Williams LD. X-ray crystallography of DNA-drug complexes. Methods in Enzymology. 340: 282-90. PMID 11494854 DOI: 10.1016/S0076-6879(01)40427-7  1
2001 Hamelberg D, Williams LD, Wilson WD. Influence of the dynamic positions of cations on the structure of the DNA minor groove: sequence-dependent effects. Journal of the American Chemical Society. 123: 7745-55. PMID 11493048 DOI: 10.1021/ja010341s  1
2000 Williams LD, Maher LJ. Electrostatic mechanisms of DNA deformation. Annual Review of Biophysics and Biomolecular Structure. 29: 497-521. PMID 10940257 DOI: 10.1146/annurev.biophys.29.1.497  1
2000 Shui X, Peek ME, Lipscomb LA, Wilkinson AP, Williams LD, Gao M, Ogata C, Roques BP, Garbay-Jaureguiberry C, Wilkinson AP, Williams LD. Effects of cationic charge on three-dimensional structures of intercalative complexes: structure of a bis-intercalated DNA complex solved by MAD phasing. Current Medicinal Chemistry. 7: 59-71. PMID 10637357  1
2000 Woods KK, McFail-Isom L, Sines CC, Howerton SB, Stephens RK, Williams LD. Monovalent cations sequester within the A-tract minor groove of [d(CGCGAATTCGCG)]2 [4] Journal of the American Chemical Society. 122: 1546-1547. DOI: 10.1021/ja9919579  1
2000 Sines CC, McFail-Isom L, Howerton SB, VanDerveer D, Williams LD. Cations mediate B-DNA conformational heterogeneity Journal of the American Chemical Society. 122: 11048-11056. DOI: 10.1021/ja002244p  1
2000 Hamelberg D, McFail-Isom L, Williams LD, David Wilson W. Flexible structure of DNA: Ion dependence of minor-groove structure and dynamics Journal of the American Chemical Society. 122: 10513-10520. DOI: 10.1021/ja000707l  1
1999 McFail-Isom L, Sines CC, Williams LD. DNA structure: cations in charge? Current Opinion in Structural Biology. 9: 298-304. PMID 10361089 DOI: 10.1016/S0959-440X(99)80040-2  1
1999 Zhang YI, Ghasemzadeh S, Kotliar AM, Kumar S, Presnell S, Williams LD. Fibers from soybean protein and poly(vinyl alcohol) Journal of Applied Polymer Science. 71: 11-19.  1
1998 McFail-Isom L, Shui X, Williams LD. Divalent cations stabilize unstacked conformations of DNA and RNA by interacting with base pi systems. Biochemistry. 37: 17105-11. PMID 9860822 DOI: 10.1021/bi982201+  1
1998 Presnell SR, Patil GS, Mura C, Jude KM, Conley JM, Bertrand JA, Kam CM, Powers JC, Williams LD. Oxyanion-mediated inhibition of serine proteases. Biochemistry. 37: 17068-81. PMID 9836602 DOI: 10.1021/bi981636u  1
1998 Shui X, Sines CC, McFail-Isom L, VanDerveer D, Williams LD. Structure of the potassium form of CGCGAATTCGCG: DNA deformation by electrostatic collapse around inorganic cations. Biochemistry. 37: 16877-87. PMID 9836580 DOI: 10.1021/bi982063o  1
1998 Milano MT, Hu GG, Williams LD, Bernhard WA. Migration of electrons and holes in crystalline d(CGATCG)-anthracycline complexes X-irradiated at 4 K. Radiation Research. 150: 101-14. PMID 9650607 DOI: 10.2307/3579650  1
1998 Shui X, McFail-Isom L, Hu GG, Williams LD. The B-DNA dodecamer at high resolution reveals a spine of water on sodium. Biochemistry. 37: 8341-55. PMID 9622486 DOI: 10.1021/bi973073c  1
1998 Davis TM, McFail-Isom L, Keane E, Williams LD. Melting of a DNA hairpin without hyperchromism. Biochemistry. 37: 6975-8. PMID 9578584 DOI: 10.1021/bi980047l  1
1998 Gasper SM, Armitage B, Shui X, Hu GG, Changjun Y, Schuster GB, Williams LD. Three-dimensional structure and reactivity of a photochemical cleavage agent bound to DNA Journal of the American Chemical Society. 120: 12402-12409. DOI: 10.1021/ja981761t  1
1997 Hu GG, Shui X, Leng F, Priebe W, Chaires JB, Williams LD. Structure of a DNA-bisdaunomycin complex. Biochemistry. 36: 5940-6. PMID 9166763 DOI: 10.1021/bi9705218  1
1997 Breslin DT, Coury JE, Anderson JR, McFail-Isom L, Kan Y, Williams LD, Bottomley LA, Schuster GB. Anthraquinone photonuclease structure determines its mode of binding to DNA and the cleavage chemistry observed [5] Journal of the American Chemical Society. 119: 5043-5044. DOI: 10.1021/ja963607h  1
1997 Coury JE, Anderson JR, McFail-Isom L, Williams LD, Bottomley LA. Scanning force microscopy of small ligand-nucleic acid complexes: Tris(o-phenanthroline)ruthenium(II) as a test for a new assay Journal of the American Chemical Society. 119: 3792-3796. DOI: 10.1021/ja9623774  1
1997 McFail-Isom L, Coury J, Holt L, Conti T, Preibe W, Chaires J, Bottomley L, Williams LD. Conversion between multiple modes of dna binding by a bis-daunomycin derivative Protein Engineering. 10: 86.  1
1996 Coury JE, McFail-Isom L, Williams LD, Bottomley LA. A novel assay for drug-DNA binding mode, affinity, and exclusion number: scanning force microscopy. Proceedings of the National Academy of Sciences of the United States of America. 93: 12283-6. PMID 8901572 DOI: 10.1073/pnas.93.22.12283  1
1996 Lipscomb LA, Zhou FX, Presnell SR, Woo RJ, Peek ME, Plaskon RR, Williams LD. Structure of DNA-porphyrin complex. Biochemistry. 35: 2818-23. PMID 8608116 DOI: 10.1021/bi952443z  1
1996 Bertrand JA, Oleksyszyn J, Kam CM, Boduszek B, Presnell S, Plaskon RR, Suddath FL, Powers JC, Williams LD. Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models. Biochemistry. 35: 3147-55. PMID 8605148 DOI: 10.1021/bi9520996  1
1996 Lipscomb LA, Zhou FX, Williams LD. Clathrate hydrates are poor models of biomolecule hydration. Biopolymers. 38: 177-81. PMID 8589251 DOI: 10.1002/(SICI)1097-0282(199602)38:2<177::AID-BIP4>3.0.CO;2-S  1
1996 Gao Q, Sood A, Shaw BR, Williams LD. 2′-Deoxycytidine-N3-cyanoborane Acta Crystallographica Section C: Crystal Structure Communications. 52: 1823-1825.  1
1995 Lipscomb LA, Peek ME, Morningstar ML, Verghis SM, Miller EM, Rich A, Essigmann JM, Williams LD. X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine. Proceedings of the National Academy of Sciences of the United States of America. 92: 719-23. PMID 7846041 DOI: 10.1073/pnas.92.3.719  1
1995 Peek ME, Lipscomb LA, Haseltine J, Gao Q, Roques BP, Garbay-Jaureguiberry C, Williams LD. Asymmetry and dynamics in bis-intercalated DNA. Bioorganic & Medicinal Chemistry. 3: 693-9. PMID 7582947 DOI: 10.1016/0968-0896(95)00064-N  1
1995 Coury JE, McFail-lsom L, Presnell S, Williams LD, Bottomley LA. Scanning probe visualization of electrostatically immobilized intercalating drug—nucleic acid complexes Journal of Vacuum Science and Technology a: Vacuum, Surfaces and Films. 13: 1746-1751. DOI: 10.1116/1.579763  1
1994 Peek ME, Lipscomb LA, Bertrand JA, Gao Q, Roques BP, Garbay-Jaureguiberry C, Williams LD. DNA distortion in bis-intercalated complexes. Biochemistry. 33: 3794-800. PMID 8142381  1
1994 Lipscomb LA, Peek ME, Zhou FX, Bertrand JA, VanDerveer D, Williams LD. Water ring structure at DNA interfaces: hydration and dynamics of DNA-anthracycline complexes. Biochemistry. 33: 3649-59. PMID 8142363  1
1994 Bancroft D, Williams LD, Rich A, Egli M. The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove. Biochemistry. 33: 1073-86. PMID 8110738  1
1992 Williams LD, Gao Q. DNA-ditercalinium interactions: implications for recognition of damaged DNA. Biochemistry. 31: 4315-24. PMID 1567878 DOI: 10.1021/bi00132a024  1
1992 MacPhail RA, Williams LD, Jones DA, Shaw BR. Variable temperature infrared spectroscopy of cytosine-guanine base pairs: tautomerism versus polarization. Journal of Biomolecular Structure & Dynamics. 9: 881-98. PMID 1524704 DOI: 10.1080/07391102.1992.10507964  1
1991 Gao Q, Williams LD, Egli M, Rabinovich D, Chen SL, Quigley GJ, Rich A. Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex. Proceedings of the National Academy of Sciences of the United States of America. 88: 2422-6. PMID 2006181  1
1991 Egli M, Williams LD, Frederick CA, Rich A. DNA-nogalamycin interactions. Biochemistry. 30: 1364-72. PMID 1991116  1
1991 Feuerstein BG, Williams LD, Basu HS, Marton LJ. Implications and concepts of polyamine-nucleic acid interactions. Journal of Cellular Biochemistry. 46: 37-47. PMID 1874798 DOI: 10.1002/jcb.240460107  1
1991 Egli M, Williams LD, Gao Q, Rich A. Structure of the pure-spermine form of Z-DNA (magnesium free) at 1-A resolution. Biochemistry. 30: 11388-402. PMID 1742278  0.8
1990 Frederick CA, Williams LD, Ughetto G, van der Marel GA, van Boom JH, Rich A, Wang AH. Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin. Biochemistry. 29: 2538-49. PMID 2334681  1
1990 Williams LD, Egli M, Qi G, Bash P, van der Marel GA, van Boom JH, Rich A, Frederick CA. Structure of nogalamycin bound to a DNA hexamer. Proceedings of the National Academy of Sciences of the United States of America. 87: 2225-9. PMID 2315315  1
1990 Williams LD, Frederick CA, Ughetto G, Rich A. Ternary interactions of spermine with DNA: 4'-epiadriamycin and other DNA: anthracycline complexes. Nucleic Acids Research. 18: 5533-41. PMID 2216725 DOI: 10.1093/nar/18.18.5533  1
1990 McCarthy JG, Williams LD, Rich A. Chemical reactivity of potassium permanganate and diethyl pyrocarbonate with B DNA: specific reactivity with short A-tracts. Biochemistry. 29: 6071-81. PMID 2166574  1
1990 Egli M, Gessner RV, Williams LD, Quigley GJ, van der Marel GA, van Boom JH, Rich A, Frederick CA. Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proceedings of the National Academy of Sciences of the United States of America. 87: 3235-9. PMID 2158107  1
1990 Williams LD, Egli M, Ughetto G, van der Marel GA, van Boom JH, Quigley GJ, Wang AH, Rich A, Frederick CA. Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate. Journal of Molecular Biology. 215: 313-20. PMID 2152325 DOI: 10.1016/S0022-2836(05)80349-3  1
1990 Williams LD, Williams NG, Shaw BR. In a model C:G base pair, one amino group rotates and the other does not Journal of the American Chemical Society. 112: 829-833.  1
1989 Williams NG, Williams LD, Shaw BR. Dimers, trimers, and tetramers of cytosine with guanine Journal of the American Chemical Society. 111: 7205-7209.  1
1988 Williams LD, Thivierge J, Goldberg IH. Specific binding of o-phenanthroline at a DNA structural lesion. Nucleic Acids Research. 16: 11607-15. PMID 2850540 DOI: 10.1093/nar/16.24.11607  1
1988 Williams LD, Goldberg IH. Selective strand scission by intercalating drugs at DNA bulges. Biochemistry. 27: 3004-11. PMID 2456781  1
1987 Williams LD, Chawla B, Shaw BR. The hydrogen bonding of cytosine with guanine: calorimetric and 1H-nmr analysis of the molecular interactions of nucleic acid bases. Biopolymers. 26: 591-603. PMID 3567328 DOI: 10.1002/bip.360260411  1
1987 Williams LD, Shaw BR. Protonated base pairs explain the ambiguous pairing properties of O6-methylguanine. Proceedings of the National Academy of Sciences of the United States of America. 84: 1779-83. PMID 3470757  1
1982 Aartsma TJ, Gouterman M, Jochum C, Kwiram AL, Pepich BV, Williams LD. Porphyrins. 43. Triplet sublevel emission of platinum tetrabenzoporphyrin by spectrothermal principal component decomposition Journal of the American Chemical Society. 104: 6278-6283. DOI: 10.1021/ja00387a021  0.36
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