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Sujay V. Kharade, Ph.D. - Publications

Affiliations: 
2011 Pharmacology University of Arkansas for Medical Sciences, United States 
Area:
Biochemistry, Physiology Biology
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lyon M, Li P, Ferreira JJ, Lazarenko RM, Kharade SV, Kramer M, McClenahan SJ, Days E, Bauer JA, Spitznagel BD, Weaver CD, Borrego Alvarez A, Puga Molina LC, Lybaert P, Khambekar S, et al. A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function. Proceedings of the National Academy of Sciences of the United States of America. 120: e2212338120. PMID 36649421 DOI: 10.1073/pnas.2212338120  0.314
2022 McClenahan SJ, Kent C, Kharade S, Isaeva E, Williams J, Han C, Terker A, Gresham R, Lazarenko R, Days E, Romaine I, Bauer J, Boutaud O, Sulikowski G, Harris R, et al. . Molecular Pharmacology. PMID 35246480 DOI: 10.1124/molpharm.121.000464  0.454
2020 Aretz C, Kharade SV, Chronister K, Trigueros RR, Rodriguez EM, Piermarini PM, Denton JS, Hopkins CR. Further SAR on the (phenylsulfonyl)piperazine scaffold as inhibitors of the Aedes aegypti Kir1 (AeKir) channel and larvicides. Chemmedchem. PMID 32926544 DOI: 10.1002/Cmdc.202000598  0.476
2020 McClenahan SJ, Kharade SV, Denton JS. Development of novel therapeutics for treating edema and SeSAME/EAST syndrome targeting heteromeric Kir4.1/5.1 potassium channels The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06158  0.494
2019 Afzal A, Figueroa EE, Kharade SV, Bittman K, Matlock BK, Flaherty DK, Denton JS. The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel. Physiological Reports. 7: e14303. PMID 31814333 DOI: 10.14814/Phy2.14303  0.468
2019 Kharade SV, Sanchez-Andres JV, Fulton MG, Shelton EJ, Blobaum AL, Engers DW, Hofmann CS, Dadi PK, Lantier L, Jacobson DA, Lindsley CW, Denton JS. Structure-activity relationships, pharmacokinetics, and pharmacodynamics of the Kir6.2/SUR1-specific channel opener, VU0071063. The Journal of Pharmacology and Experimental Therapeutics. PMID 31201216 DOI: 10.1124/Jpet.119.257204  0.533
2019 Aretz C, Morwitzer MJ, Sanford A, Hogan AM, Portillo M, Kharade SV, Kramer M, Mcarthey J, Trigueros RR, Piermarini PM, Denton JS, Hopkins CR. Discovery and characterization of 2-nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)-N-(pyridin-4-ylmethyl)anilines as novel inhibitors of the Aedes aegypti Kir1 (AeKir1) channel. Acs Infectious Diseases. PMID 30832472 DOI: 10.1021/Acsinfecdis.8B00368  0.506
2018 Kozek KA, Du Y, Sharma S, Prael FJ, Spitznagel BD, Kharade SV, Denton JS, Hopkins CR, Weaver CD. Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-gated, Inwardly-rectifying, Potassium (GIRK) Channels. Acs Chemical Neuroscience. PMID 30136838 DOI: 10.1021/Acschemneuro.8B00287  0.584
2018 Kharade SV, Kurata H, Bender A, Blobaum AL, Figueroa EE, Duran AM, Kramer M, Days E, Vinson P, Flores D, Satlin LM, Meiler J, Weaver CD, Lindsley CW, Hopkins CR, et al. Discovery, characterization, and effects on renal fluid and electrolyte excretion of the Kir4.1 potassium channel pore blocker, VU0134992. Molecular Pharmacology. PMID 29895592 DOI: 10.1124/Mol.118.112359  0.484
2018 Sammons MF, Kharade SV, Filipski KJ, Boehm M, Smith AC, Shavnya A, Fernando DP, Dowling MS, Carpino PA, Castle NA, Zellmer SG, Antonio BM, Gosset JR, Carlo A, Denton JS. Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors. Acs Medicinal Chemistry Letters. 9: 125-130. PMID 29456800 DOI: 10.1021/Acsmedchemlett.7B00481  0.325
2017 Kharade S, Sheehan J, Figueroa E, Meiler J, Denton J. Pore polarity and charge determine differential block of Kir1.1 and Kir7.1 potassium channels by the small-molecule inhibitor VU590. Molecular Pharmacology. PMID 28619748 DOI: 10.1124/Mol.117.108472  0.481
2016 Detweiler ND, Song L, McClenahan SJ, Versluis RJ, Kharade SV, Kurten RC, Rhee SW, Rusch NJ. BK channels in rat and human pulmonary smooth muscle cells are BKα-β1 functional complexes lacking the oxygen-sensitive stress axis regulated exon insert. Pulmonary Circulation. 6: 563-575. PMID 28090300 DOI: 10.1086/688838  0.72
2016 Swale DR, Kurata H, Kharade SV, Sheehan JH, Raphemot RR, Voigtritter KR, Figueroa E, Meiler J, Flobaum AL, Lindsley CW, Hopkins CR, Denton JS. ML418: The first selective, sub-micromolar pore blocker of Kir7.1 potassium channels. Acs Chemical Neuroscience. PMID 27184474 DOI: 10.1021/Acschemneuro.6B00111  0.524
2016 Kharade SV, Nichols C, Denton JS. The shifting landscape of KATP channelopathies and the need for 'sharper' therapeutics. Future Medicinal Chemistry. PMID 27161588 DOI: 10.4155/Fmc-2016-0005  0.455
2015 Kharade SV, Flores D, Lindsley CW, Satlin LM, Denton JS. ROMK Inhibitor Actions in the Nephron Probed with Diuretics. American Journal of Physiology. Renal Physiology. ajprenal.00423.2015. PMID 26661652 DOI: 10.1152/Ajprenal.00423.2015  0.385
2014 Swale DR, Kharade SV, Denton JS. Cardiac and renal inward rectifier potassium channel pharmacology: emerging tools for integrative physiology and therapeutics. Current Opinion in Pharmacology. 15: 7-15. PMID 24721648 DOI: 10.1016/J.Coph.2013.11.002  0.531
2014 Srivastava A, Song L, Kharade S, Fletcher T, Rhee S, Rusch N. The β3 subunit: a key regulator of vascular calcium channel expression (1057.10) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1057.10  0.61
2013 Kharade SV, Sonkusare SK, Srivastava AK, Thakali KM, Fletcher TW, Rhee SW, Rusch NJ. The β3 subunit contributes to vascular calcium channel upregulation and hypertension in angiotensin II-infused C57BL/6 mice. Hypertension. 61: 137-42. PMID 23129698 DOI: 10.1161/Hypertensionaha.112.197863  0.675
2012 Thakali KM, Pathan AR, Kharade SV, Rusch NJ. Potassium, sodium, and chloride channels in smooth muscle cells Muscle. 2: 1133-1143. DOI: 10.1016/B978-0-12-381510-1.00084-3  0.612
2010 Thakali KM, Kharade SV, Sonkusare SK, Rhee SW, Stimers JR, Rusch NJ. Intracellular Ca2+ silences L-type Ca2+ channels in mesenteric veins: mechanism of venous smooth muscle resistance to calcium channel blockers. Circulation Research. 106: 739-47. PMID 20044515 DOI: 10.1161/Circresaha.109.206763  0.703
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