Frederick R. Maxfield - Publications

Affiliations: 
Biochemistry Weill Cornell Medical College, New York, NY, United States 
Website:
http://weill.cornell.edu/research/frmaxfield/biography.html

179 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pipalia NH, Saad SZ, Subramanian K, Cross A, Al-Motawa A, Garg K, Blagg BSJ, Neckers L, Helquist P, Wiest O, Ory DS, Maxfield FR. HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts. Journal of Lipid Research. 100114. PMID 34481829 DOI: 10.1016/j.jlr.2021.100114  0.727
2020 Feng T, Sheng RR, Solé-Domènech S, Ullah M, Zhou X, Mendoza CS, Enriquez LCM, Katz II, Paushter DH, Sullivan PM, Wu X, Maxfield FR, Hu F. A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination. Brain : a Journal of Neurology. PMID 32572497 DOI: 10.1093/Brain/Awaa154  0.311
2020 Iaea DB, Spahr ZR, Singh RK, Chan RB, Zhou B, Bareja R, Elemento O, Di Paolo G, Zhang X, Maxfield FR. Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 158609. PMID 31917335 DOI: 10.1016/J.Bbalip.2020.158609  0.415
2019 Singh RK, Lund FW, Haka AS, Maxfield FR. High-density lipoprotein or cyclodextrin extraction of cholesterol from aggregated LDL reduces foam cell formation. Journal of Cell Science. PMID 31719160 DOI: 10.1242/Jcs.237271  0.359
2019 Maxfield FR, Barbosa-Lorenzi VC, Singh RK. Digestive Exophagy: Phagocyte digestion of objects too large for phagocytosis. Traffic (Copenhagen, Denmark). PMID 31664749 DOI: 10.1111/Tra.12712  0.322
2019 Singh RK, Haka AS, Asmal A, Barbosa-Lorenzi VC, Grosheva I, Chin HF, Xiong Y, Hla T, Maxfield FR. TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313200. PMID 31597445 DOI: 10.1161/Atvbaha.119.313200  0.348
2019 Davidson J, Molitor E, Moores S, Gale SE, Subramanian K, Jiang X, Sidhu R, Kell P, Zhang J, Fujiwara H, Davidson C, Helquist P, Melancon BJ, Grigalunas M, Liu G, ... ... Maxfield FR, et al. 2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 31051283 DOI: 10.1016/J.Bbalip.2019.04.011  0.314
2018 Singh RK, Haka AS, Bhardwaj P, Zha X, Maxfield FR. Dynamic Actin Reorganization and Vav/Cdc42-Dependent Actin Polymerization Promote Macrophage Aggregated LDL (Low-Density Lipoprotein) Uptake and Catabolism. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA118312087. PMID 30580573 DOI: 10.1161/Atvbaha.118.312087  0.34
2018 Courtney KC, Fung KY, Maxfield FR, Fairn GD, Zha X. Comment on 'Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol'. Elife. 7. PMID 30422112 DOI: 10.7554/Elife.38493  0.368
2018 Solé-Domènech S, Rojas AV, Maisuradze GG, Scheraga HA, Lobel P, Maxfield FR. Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 29378960 DOI: 10.1073/Pnas.1719808115  0.394
2017 Iaea DB, Maxfield FR. Membrane order in the plasma membrane and endocytic recycling compartment. Plos One. 12: e0188041. PMID 29125865 DOI: 10.1371/Journal.Pone.0188041  0.349
2017 Stefan CJ, Trimble WS, Grinstein S, Drin G, Reinisch K, De Camilli P, Cohen S, Valm AM, Lippincott-Schwartz J, Levine TP, Iaea DB, Maxfield FR, Futter CE, Eden ER, Judith D, et al. Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers. Bmc Biology. 15: 102. PMID 29089042 DOI: 10.1186/S12915-017-0432-0  0.359
2017 Jena PV, Roxbury D, Galassi TV, Akkari L, Horoszko CP, Iaea DB, Budhathoki-Uprety J, Pipalia N, Haka AS, Harvey JD, Mittal J, Maxfield FR, Joyce JA, Heller DA. A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux. Acs Nano. PMID 28898055 DOI: 10.1021/Acsnano.7B04743  0.369
2017 Singh RK, Haka AS, Brumfield A, Grosheva I, Bhardwaj P, Chin HF, Xiong Y, Hla T, Maxfield FR. Ceramide Activation of RhoA/Rho Kinase Impairs Actin Polymerization during Aggregated LDL Catabolism. Journal of Lipid Research. PMID 28814641 DOI: 10.1194/Jlr.M076398  0.317
2017 Iaea DB, Mao S, Lund FW, Maxfield FR. Role of STARD4 in sterol transport between the endocytic recycling compartment and the plasma membrane. Molecular Biology of the Cell. PMID 28209730 DOI: 10.1091/Mbc.E16-07-0499  0.36
2017 Pipalia NH, Subramanian K, Mao S, Ralph H, Hutt DM, Scott SM, Balch WE, Maxfield FR. Histone deacetylase inhibitors correct the cholesterol storage defect in most NPC1 mutant cells. Journal of Lipid Research. PMID 28193631 DOI: 10.1194/Jlr.M072140  0.389
2017 Shore DM, Iaea DB, Rusinova R, Khelashvili G, Cuendet MA, Andersen OS, Maxfield FR, Weinstein H. Vectorial Cholesterol Transport by STARD4 is Mediated by Specific PIP 2 Membrane Composition Biophysical Journal. 112: 87a. DOI: 10.1016/J.Bpj.2016.11.511  0.377
2016 Solé-Domènech S, Cruz DL, Capetillo-Zarate E, Maxfield FR. The Endocytic Pathway in Microglia During Health, Aging and Alzheimer's Disease. Ageing Research Reviews. PMID 27421577 DOI: 10.1016/J.Arr.2016.07.002  0.314
2016 Maxfield FR, Iaea DB, Pipalia NH. Role of STARD4 and NPC1 in intracellular sterol transport. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 1-8. PMID 27421092 DOI: 10.1139/Bcb-2015-0154  0.393
2016 Haka AS, Barbosa-Lorenzi VC, Lee HJ, Falcone DJ, Hudis CA, Dannenberg AJ, Maxfield FR. Exocytosis of Macrophage Lysosomes Leads to Digestion of Apoptotic Adipocytes and Foam Cell Formation. Journal of Lipid Research. PMID 27044658 DOI: 10.1194/Jlr.M064089  0.332
2016 Singh RK, Barbosa-Lorenzi VC, Lund FW, Grosheva I, Maxfield FR, Haka AS. Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse. Journal of Cell Science. PMID 26801085 DOI: 10.1242/Jcs.181743  0.356
2015 Iaea DB, Gale SE, Bielska AA, Krishnan K, Fujiwara H, Jiang H, Maxfield FR, Schlesinger PH, Covey DF, Schaffer JE, Ory DS. A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol. Journal of Lipid Research. PMID 26497473 DOI: 10.1194/Jlr.D064287  0.42
2015 Haka AS, Singh RK, Grosheva I, Hoffner H, Capetillo-Zarate E, Chin HF, Anandasabapathy N, Maxfield FR. Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2092-103. PMID 26293468 DOI: 10.1161/Atvbaha.115.305843  0.357
2015 Iaea DB, Dikiy I, Kiburu I, Eliezer D, Maxfield FR. STARD4 Membrane Interactions and Sterol Binding. Biochemistry. 54: 4623-36. PMID 26168008 DOI: 10.1021/Acs.Biochem.5B00618  0.364
2015 Praggastis M, Tortelli B, Zhang J, Fujiwara H, Sidhu R, Chacko A, Chen Z, Chung C, Lieberman AP, Sikora J, Davidson C, Walkley SU, Pipalia NH, Maxfield FR, Schaffer JE, et al. A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8091-106. PMID 26019327 DOI: 10.1523/Jneurosci.4173-14.2015  0.331
2015 Iaea DB, Maxfield FR. Cholesterol trafficking and distribution. Essays in Biochemistry. 57: 43-55. PMID 25658343 DOI: 10.1042/Bse0570043  0.411
2014 Pipalia NH, Maxfield FR. Therapeutic potential of histone deacetylase inhibitor for treatment of Niemann-Pick type C1 disease Molecular Cytogenetics. DOI: 10.1186/1755-8166-7-S1-O2  0.343
2013 Helquist P, Maxfield FR, Wiech NL, Wiest O. Treatment of Niemann--pick type C disease by histone deacetylase inhibitors. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 688-97. PMID 24048860 DOI: 10.1007/S13311-013-0217-2  0.328
2013 Haka AS, Grosheva I, Singh RK, Maxfield FR. Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1768-78. PMID 23702659 DOI: 10.1161/Atvbaha.112.301109  0.379
2012 Tortorella LL, Pipalia NH, Mukherjee S, Pastan I, Fitzgerald D, Maxfield FR. Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary. Plos One. 7: e47320. PMID 23056628 DOI: 10.1371/Journal.Pone.0047320  0.474
2012 Garbarino J, Pan M, Chin HF, Lund FW, Maxfield FR, Breslow JL. STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC. Journal of Lipid Research. 53: 2716-25. PMID 23033213 DOI: 10.1194/Jlr.M032227  0.422
2012 Haka AS, Potteaux S, Fraser H, Randolph GJ, Maxfield FR. Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy. Plos One. 7: e44823. PMID 23024767 DOI: 10.1371/Journal.Pone.0044823  0.321
2012 Maxfield FR, Wüstner D. Analysis of cholesterol trafficking with fluorescent probes. Methods in Cell Biology. 108: 367-93. PMID 22325611 DOI: 10.1016/B978-0-12-386487-1.00017-1  0.371
2011 Mesmin B, Pipalia NH, Lund FW, Ramlall TF, Sokolov A, Eliezer D, Maxfield FR. STARD4 abundance regulates sterol transport and sensing. Molecular Biology of the Cell. 22: 4004-15. PMID 21900492 DOI: 10.1091/Mbc.E11-04-0372  0.383
2011 Majumdar A, Capetillo-Zarate E, Cruz D, Gouras GK, Maxfield FR. Degradation of Alzheimer's amyloid fibrils by microglia requires delivery of ClC-7 to lysosomes. Molecular Biology of the Cell. 22: 1664-76. PMID 21441306 DOI: 10.1091/Mbc.E10-09-0745  0.333
2011 Pipalia NH, Cosner CC, Huang A, Chatterjee A, Bourbon P, Farley N, Helquist P, Wiest O, Maxfield FR. Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 108: 5620-5. PMID 21436030 DOI: 10.1073/Pnas.1014890108  0.369
2011 Pagler TA, Wang M, Mondal M, Murphy AJ, Westerterp M, Moore KJ, Maxfield FR, Tall AR. Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling. Circulation Research. 108: 194-200. PMID 21148432 DOI: 10.1161/Circresaha.110.228619  0.366
2011 Rosenbaum AI, Maxfield FR. Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches. Journal of Neurochemistry. 116: 789-95. PMID 20807315 DOI: 10.1111/J.1471-4159.2010.06976.X  0.741
2010 Rujoi M, Pipalia NH, Maxfield FR. Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells. Plos One. 5: e12788. PMID 20877719 DOI: 10.1371/Journal.Pone.0012788  0.412
2010 Maxfield FR, van Meer G. Cholesterol, the central lipid of mammalian cells. Current Opinion in Cell Biology. 22: 422-9. PMID 20627678 DOI: 10.1016/J.Ceb.2010.05.004  0.398
2010 Rosenbaum AI, Cosner CC, Mariani CJ, Maxfield FR, Wiest O, Helquist P. Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics. Journal of Medicinal Chemistry. 53: 5281-9. PMID 20557099 DOI: 10.1021/Jm100499S  0.718
2010 Devlin C, Pipalia NH, Liao X, Schuchman EH, Maxfield FR, Tabas I. Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect. Traffic (Copenhagen, Denmark). 11: 601-15. PMID 20412078 DOI: 10.1111/J.1600-0854.2010.01046.X  0.397
2010 Rosenbaum AI, Zhang G, Warren JD, Maxfield FR. Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 5477-82. PMID 20212119 DOI: 10.1073/Pnas.0914309107  0.748
2010 Haka AS, Grosheva I, Chiang E, Buxbaum AR, Baird BA, Pierini LM, Maxfield FR. Macrophages Create a Lysosomal Synapse to Digest Aggregated Lipoproteins Biophysical Journal. 98: 580a. DOI: 10.1016/J.Bpj.2009.12.3151  0.373
2009 Haka AS, Grosheva I, Chiang E, Buxbaum AR, Baird BA, Pierini LM, Maxfield FR. Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins. Molecular Biology of the Cell. 20: 4932-40. PMID 19812252 DOI: 10.1091/Mbc.E09-07-0559  0.348
2009 Cosner CC, Markiewicz JT, Bourbon P, Mariani CJ, Wiest O, Rujoi M, Rosenbaum AI, Huang AY, Maxfield FR, Helquist P. Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics. Journal of Medicinal Chemistry. 52: 6494-8. PMID 19772346 DOI: 10.1021/Jm900707N  0.726
2009 Rosenbaum AI, Rujoi M, Huang AY, Du H, Grabowski GA, Maxfield FR. Chemical screen to reduce sterol accumulation in Niemann-Pick C disease cells identifies novel lysosomal acid lipase inhibitors. Biochimica Et Biophysica Acta. 1791: 1155-65. PMID 19699313 DOI: 10.1016/J.Bbalip.2009.08.005  0.743
2009 Grosheva I, Haka AS, Qin C, Pierini LM, Maxfield FR. Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1615-21. PMID 19556523 DOI: 10.1161/Atvbaha.109.191882  0.373
2009 Mesmin B, Maxfield FR. Intracellular sterol dynamics. Biochimica Et Biophysica Acta. 1791: 636-45. PMID 19286471 DOI: 10.1016/J.Bbalip.2009.03.002  0.395
2009 Mondal M, Mesmin B, Mukherjee S, Maxfield FR. Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells. Molecular Biology of the Cell. 20: 581-8. PMID 19019985 DOI: 10.1091/Mbc.E08-07-0785  0.384
2009 Maxfield F. The interplay between lipid and protein trafficking Biophysical Journal. 96: 564a. DOI: 10.1016/J.Bpj.2008.12.3695  0.326
2008 Adachi S, Nagao T, To S, Joe AK, Shimizu M, Matsushima-Nishiwaki R, Kozawa O, Moriwaki H, Maxfield FR, Weinstein IB. (-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells. Carcinogenesis. 29: 1986-93. PMID 18586691 DOI: 10.1093/Carcin/Bgn128  0.345
2008 Pan M, Maitin V, Parathath S, Andreo U, Lin SX, St Germain C, Yao Z, Maxfield FR, Williams KJ, Fisher EA. Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for late-stage quality control. Proceedings of the National Academy of Sciences of the United States of America. 105: 5862-7. PMID 18391222 DOI: 10.1073/Pnas.0707460104  0.308
2008 Ding T, Li Z, Hailemariam T, Mukherjee S, Maxfield FR, Wu MP, Jiang XC. SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis. Journal of Lipid Research. 49: 376-85. PMID 17982138 DOI: 10.1194/Jlr.M700401-Jlr200  0.371
2008 Majumdar A, Chung H, Dolios G, Wang R, Asamoah N, Lobel P, Maxfield FR. Degradation of fibrillar forms of Alzheimer's amyloid beta-peptide by macrophages. Neurobiology of Aging. 29: 707-15. PMID 17222479 DOI: 10.1016/J.Neurobiolaging.2006.12.001  0.316
2007 Adachi S, Nagao T, Ingolfsson HI, Maxfield FR, Andersen OS, Kopelovich L, Weinstein IB. The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells. Cancer Research. 67: 6493-501. PMID 17616711 DOI: 10.1158/0008-5472.Can-07-0411  0.37
2007 Nagao T, Qin C, Grosheva I, Maxfield FR, Pierini LM. Elevated cholesterol levels in the plasma membranes of macrophages inhibit migration by disrupting RhoA regulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1596-602. PMID 17495238 DOI: 10.1161/Atvbaha.107.145086  0.396
2007 Tortorella LL, Schapiro FB, Maxfield FR. Role of an acidic cluster/dileucine motif in cation-independent mannose 6-phosphate receptor traffic. Traffic (Copenhagen, Denmark). 8: 402-13. PMID 17319895 DOI: 10.1111/J.1600-0854.2007.00541.X  0.309
2007 Majumdar A, Cruz D, Asamoah N, Buxbaum A, Sohar I, Lobel P, Maxfield FR. Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils. Molecular Biology of the Cell. 18: 1490-6. PMID 17314396 DOI: 10.1091/Mbc.E06-10-0975  0.328
2007 Pipalia NH, Hao M, Mukherjee S, Maxfield FR. Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect. Traffic (Copenhagen, Denmark). 8: 130-41. PMID 17156101 DOI: 10.1111/J.1600-0854.2006.00513.X  0.445
2006 Walczak W, Pipalia NH, Soni M, Faruqi AF, Ralph H, Maxfield FR, Webb BL. Parallel analysis of v-Src mutant protein function using reverse transfection cell arrays. Combinatorial Chemistry & High Throughput Screening. 9: 711-8. PMID 17100576 DOI: 10.2174/138620706778700116  0.326
2006 Murcia M, Faráldo-Gómez JD, Maxfield FR, Roux B. Modeling the structure of the StART domains of MLN64 and StAR proteins in complex with cholesterol. Journal of Lipid Research. 47: 2614-30. PMID 16990645 DOI: 10.1194/Jlr.M600232-Jlr200  0.343
2006 Maxfield FR, Menon AK. Intracellular sterol transport and distribution. Current Opinion in Cell Biology. 18: 379-85. PMID 16806879 DOI: 10.1016/J.Ceb.2006.06.012  0.369
2006 Maxfield FR, Mondal M. Sterol and lipid trafficking in mammalian cells. Biochemical Society Transactions. 34: 335-9. PMID 16709155 DOI: 10.1042/Bst0340335  0.395
2006 Liang XJ, Mukherjee S, Shen DW, Maxfield FR, Gottesman MM. Endocytic recycling compartments altered in cisplatin-resistant cancer cells. Cancer Research. 66: 2346-53. PMID 16489040 DOI: 10.1158/0008-5472.Can-05-3436  0.307
2006 Qin C, Nagao T, Grosheva I, Maxfield FR, Pierini LM. Elevated plasma membrane cholesterol content alters macrophage signaling and function. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 372-8. PMID 16306428 DOI: 10.1161/01.Atv.0000197848.67999.E1  0.403
2006 Pipalia NH, Huang A, Ralph H, Rujoi M, Maxfield FR. Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells. Journal of Lipid Research. 47: 284-301. PMID 16288097 DOI: 10.1194/Jlr.M500388-Jlr200  0.338
2005 Maxfield FR, Tabas I. Role of cholesterol and lipid organization in disease. Nature. 438: 612-21. PMID 16319881 DOI: 10.1038/Nature04399  0.364
2005 Wüstner D, Mondal M, Tabas I, Maxfield FR. Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells. Traffic (Copenhagen, Denmark). 6: 396-412. PMID 15813750 DOI: 10.1111/J.1600-0854.2005.00285.X  0.417
2004 Mukherjee S, Maxfield FR. Lipid and cholesterol trafficking in NPC. Biochimica Et Biophysica Acta. 1685: 28-37. PMID 15465424 DOI: 10.1016/J.Bbalip.2004.08.009  0.405
2004 Li Y, Ge M, Ciani L, Kuriakose G, Westover EJ, Dura M, Covey DF, Freed JH, Maxfield FR, Lytton J, Tabas I. Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages. The Journal of Biological Chemistry. 279: 37030-9. PMID 15215242 DOI: 10.1074/Jbc.M405195200  0.365
2004 Schapiro FB, Soe TT, Mallet WG, Maxfield FR. Role of cytoplasmic domain serines in intracellular trafficking of furin. Molecular Biology of the Cell. 15: 2884-94. PMID 15075375 DOI: 10.1091/Mbc.E03-09-0653  0.357
2004 Recht PA, Tepedino GJ, Siecke NW, Buckley MT, Mandeville JT, Maxfield FR, Levin RI. Oxalic acid alters intracellular calcium in endothelial cells. Atherosclerosis. 173: 321-8. PMID 15064109 DOI: 10.1016/J.Atherosclerosis.2003.11.023  0.315
2004 Hao M, Mukherjee S, Sun Y, Maxfield FR. Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes. The Journal of Biological Chemistry. 279: 14171-8. PMID 14734557 DOI: 10.1074/Jbc.M309793200  0.414
2004 Wüstner D, Mondal M, Huang A, Maxfield FR. Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells. Journal of Lipid Research. 45: 427-37. PMID 14679167 DOI: 10.1194/Jlr.M300440-Jlr200  0.407
2004 Lin SX, Mallet WG, Huang AY, Maxfield FR. Endocytosed cation-independent mannose 6-phosphate receptor traffics via the endocytic recycling compartment en route to the trans-Golgi network and a subpopulation of late endosomes. Molecular Biology of the Cell. 15: 721-33. PMID 14595110 DOI: 10.1091/Mbc.E03-07-0497  0.318
2003 Patel M, Morrow J, Maxfield FR, Strickland DK, Greenberg S, Tabas I. The cytoplasmic domain of the low density lipoprotein (LDL) receptor-related protein, but not that of the LDL receptor, triggers phagocytosis. The Journal of Biological Chemistry. 278: 44799-807. PMID 12941948 DOI: 10.1074/Jbc.M308982200  0.36
2003 Mamdouh Z, Chen X, Pierini LM, Maxfield FR, Muller WA. Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis. Nature. 421: 748-53. PMID 12610627 DOI: 10.1038/Nature01300  0.327
2003 Pierini LM, Eddy RJ, Fuortes M, Seveau S, Casulo C, Maxfield FR. Membrane lipid organization is critical for human neutrophil polarization. The Journal of Biological Chemistry. 278: 10831-41. PMID 12522144 DOI: 10.1074/Jbc.M212386200  0.377
2003 Sun Y, Hao M, Luo Y, Liang CP, Silver DL, Cheng C, Maxfield FR, Tall AR. Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure. The Journal of Biological Chemistry. 278: 5813-20. PMID 12482877 DOI: 10.1074/Jbc.M208687200  0.42
2002 Maxfield FR. Plasma membrane microdomains. Current Opinion in Cell Biology. 14: 483-7. PMID 12383800 DOI: 10.1016/S0955-0674(02)00351-4  0.332
2002 Maxfield FR, Wüstner D. Intracellular cholesterol transport. The Journal of Clinical Investigation. 110: 891-8. PMID 12370264 DOI: 10.1172/Jci16500  0.395
2002 Wüstner D, Herrmann A, Hao M, Maxfield FR. Rapid nonvesicular transport of sterol between the plasma membrane domains of polarized hepatic cells. The Journal of Biological Chemistry. 277: 30325-36. PMID 12050151 DOI: 10.1074/Jbc.M202626200  0.367
2002 Lin SX, Gundersen GG, Maxfield FR. Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin. Molecular Biology of the Cell. 13: 96-109. PMID 11809825 DOI: 10.1091/Mbc.01-05-0224  0.325
2002 Hao M, Lin SX, Karylowski OJ, Wüstner D, McGraw TE, Maxfield FR. Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle. The Journal of Biological Chemistry. 277: 609-17. PMID 11682487 DOI: 10.1074/Jbc.M108861200  0.415
2001 Hao M, Mukherjee S, Maxfield FR. Cholesterol depletion induces large scale domain segregation in living cell membranes. Proceedings of the National Academy of Sciences of the United States of America. 98: 13072-7. PMID 11698680 DOI: 10.1073/Pnas.231377398  0.41
2001 Seveau S, Eddy RJ, Maxfield FR, Pierini LM. Cytoskeleton-dependent membrane domain segregation during neutrophil polarization. Molecular Biology of the Cell. 12: 3550-62. PMID 11694588 DOI: 10.1091/Mbc.12.11.3550  0.324
2001 Bennett EM, Lin SX, Towler MC, Maxfield FR, Brodsky FM. Clathrin hub expression affects early endosome distribution with minimal impact on receptor sorting and recycling. Molecular Biology of the Cell. 12: 2790-9. PMID 11553717 DOI: 10.1091/Mbc.12.9.2790  0.35
2001 Pierini LM, Maxfield FR. Flotillas of lipid rafts fore and aft. Proceedings of the National Academy of Sciences of the United States of America. 98: 9471-3. PMID 11504934 DOI: 10.1073/Pnas.181353098  0.38
2001 Sakr SW, Eddy RJ, Barth H, Wang F, Greenberg S, Maxfield FR, Tabas I. The uptake and degradation of matrix-bound lipoproteins by macrophages require an intact actin Cytoskeleton, Rho family GTPases, and myosin ATPase activity. The Journal of Biological Chemistry. 276: 37649-58. PMID 11477084 DOI: 10.1074/Jbc.M105129200  0.366
2001 Matyash V, Geier C, Henske A, Mukherjee S, Hirsh D, Thiele C, Grant B, Maxfield FR, Kurzchalia TV. Distribution and transport of cholesterol in Caenorhabditis elegans. Molecular Biology of the Cell. 12: 1725-36. PMID 11408580 DOI: 10.1091/Mbc.12.6.1725  0.391
2001 Lin SX, Grant B, Hirsh D, Maxfield FR. Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells. Nature Cell Biology. 3: 567-72. PMID 11389441 DOI: 10.1038/35078543  0.319
2001 Wüstner D, Mukherjee S, Maxfield FR, Müller P, Herrmann A. Vesicular and nonvesicular transport of phosphatidylcholine in polarized HepG2 cells. Traffic (Copenhagen, Denmark). 2: 277-96. PMID 11285138 DOI: 10.1034/J.1600-0854.2001.9O135.X  0.353
2001 Hao M, Maxfield FR. Analyzing microdomains in biological membranes using fluorescence techniques Journal of Fluorescence. 11: 287-295. DOI: 10.1023/A:1013970806671  0.336
2000 Mukherjee S, Maxfield FR. Role of membrane organization and membrane domains in endocytic lipid trafficking. Traffic (Copenhagen, Denmark). 1: 203-11. PMID 11208103 DOI: 10.1034/J.1600-0854.2000.010302.X  0.35
2000 Khelef N, Soe TT, Quehenberger O, Beatini N, Tabas I, Maxfield FR. Enrichment of acyl coenzyme A:cholesterol O-acyltransferase near trans-golgi network and endocytic recycling compartment. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1769-76. PMID 10894815 DOI: 10.1161/01.Atv.20.7.1769  0.409
2000 Hao M, Maxfield FR. Characterization of rapid membrane internalization and recycling. The Journal of Biological Chemistry. 275: 15279-86. PMID 10809763 DOI: 10.1074/Jbc.275.20.15279  0.383
2000 Brazil MI, Chung H, Maxfield FR. Effects of incorporation of immunoglobulin G and complement component C1q on uptake and degradation of Alzheimer's disease amyloid fibrils by microglia. The Journal of Biological Chemistry. 275: 16941-7. PMID 10747968 DOI: 10.1074/Jbc.M000937200  0.339
2000 Pierini LM, Lawson MA, Eddy RJ, Hendey B, Maxfield FR. Oriented endocytic recycling of α5β1 in motile neutrophils Blood. 95: 2471-2480. DOI: 10.1182/Blood.V95.8.2471.007K26A_2471_2480  0.346
1999 Mukherjee S, Maxfield FR. Cholesterol: stuck in traffic. Nature Cell Biology. 1: E37-8. PMID 10559892 DOI: 10.1038/10030  0.384
1999 Buton X, Mamdouh Z, Ghosh R, Du H, Kuriakose G, Beatini N, Grabowski GA, Maxfield FR, Tabas I. Unique cellular events occurring during the initial interaction of macrophages with matrix-retained or methylated aggregated low density lipoprotein (LDL). Prolonged cell-surface contact during which ldl-cholesteryl ester hydrolysis exceeds ldl protein degradation. The Journal of Biological Chemistry. 274: 32112-21. PMID 10542246 DOI: 10.1074/Jbc.274.45.32112  0.383
1999 Mallet WG, Maxfield FR. Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways. The Journal of Cell Biology. 146: 345-59. PMID 10465644 DOI: 10.1083/Jcb.146.2.345  0.336
1999 Mukherjee S, Soe TT, Maxfield FR. Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails. The Journal of Cell Biology. 144: 1271-84. PMID 10087269 DOI: 10.1083/Jcb.144.6.1271  0.342
1998 Mukherjee S, Zha X, Tabas I, Maxfield FR. Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Biophysical Journal. 75: 1915-25. PMID 9746532 DOI: 10.1016/S0006-3495(98)77632-5  0.431
1998 Ghosh RN, Mallet WG, Soe TT, McGraw TE, Maxfield FR. An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells. The Journal of Cell Biology. 142: 923-36. PMID 9722606 DOI: 10.1083/Jcb.142.4.923  0.344
1998 Mayor S, Sabharanjak S, Maxfield FR. Cholesterol-dependent retention of GPI-anchored proteins in endosomes. The Embo Journal. 17: 4626-38. PMID 9707422 DOI: 10.1093/Emboj/17.16.4626  0.602
1998 Khelef N, Buton X, Beatini N, Wang H, Meiner V, Chang TY, Farese RV, Maxfield FR, Tabas I. Immunolocalization of acyl-coenzyme A:cholesterol O-acyltransferase in macrophages. The Journal of Biological Chemistry. 273: 11218-24. PMID 9556612 DOI: 10.1074/Jbc.273.18.11218  0.392
1998 Zha X, Pierini LM, Leopold PL, Skiba PJ, Tabas I, Maxfield FR. Sphingomyelinase treatment induces ATP-independent endocytosis. The Journal of Cell Biology. 140: 39-47. PMID 9425152 DOI: 10.1083/Jcb.140.1.39  0.37
1998 Maxfield FR, Ghosh RN, Mallet WG, Soe TT, Leopold PL, Cohen-Gould L, Mayor S, Mukherjee S, Zha X, McGraw TE. Characterization of Endocytic Pathways by Quantitative Fluorescence Microscopy Microscopy and Microanalysis. 4: 1024-1025. DOI: 10.1017/S1431927600025241  0.488
1997 Paresce DM, Chung H, Maxfield FR. Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells. The Journal of Biological Chemistry. 272: 29390-7. PMID 9361021 DOI: 10.1074/Jbc.272.46.29390  0.311
1997 Zha X, Tabas I, Leopold PL, Jones NL, Maxfield FR. Evidence for prolonged cell-surface contact of acetyl-LDL before entry into macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1421-31. PMID 9261276 DOI: 10.1161/01.Atv.17.7.1421  0.412
1997 Maxfield FR, Mayor S. Cell surface dynamics of GPI-anchored proteins. Advances in Experimental Medicine and Biology. 419: 355-64. PMID 9193677 DOI: 10.1007/978-1-4419-8632-0_47  0.548
1997 Presley JF, Mayor S, McGraw TE, Dunn KW, Maxfield FR. Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling. The Journal of Biological Chemistry. 272: 13929-36. PMID 9153255 DOI: 10.1074/Jbc.272.21.13929  0.539
1996 Johnson AO, Ghosh RN, Dunn KW, Garippa R, Park J, Mayor S, Maxfield FR, McGraw TE. Transferrin receptor containing the SDYQRL motif of TGN38 causes a reorganization of the recycling compartment but is not targeted to the TGN. The Journal of Cell Biology. 135: 1749-62. PMID 8991088 DOI: 10.1083/Jcb.135.6.1749  0.558
1996 Paresce DM, Ghosh RN, Maxfield FR. Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron. 17: 553-65. PMID 8816718 DOI: 10.1016/S0896-6273(00)80187-7  0.307
1996 Skiba PJ, Zha X, Maxfield FR, Schissel SL, Tabas I. The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent. The Journal of Biological Chemistry. 271: 13392-400. PMID 8662777 DOI: 10.1074/Jbc.271.23.13392  0.389
1995 Ghosh RN, Maxfield FR. Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells. The Journal of Cell Biology. 128: 549-61. PMID 7860630 DOI: 10.1083/Jcb.128.4.549  0.356
1995 Schwiegelshohn B, Presley JF, Gorecki M, Vogel T, Carpentier YA, Maxfield FR, Deckelbaum RJ. Effects of apoprotein E on intracellular metabolism of model triglyceride-rich particles are distinct from effects on cell particle uptake. The Journal of Biological Chemistry. 270: 1761-9. PMID 7829512 DOI: 10.1074/Jbc.270.4.1761  0.303
1995 Marsh EW, Leopold PL, Jones NL, Maxfield FR. Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. The Journal of Cell Biology. 129: 1509-22. PMID 7790351 DOI: 10.1083/Jcb.129.6.1509  0.363
1995 Schissel SL, Beatini N, Zha X, Maxfield FR, Tabas I. Effect and cellular site of action of cysteine protease inhibitors on the cholesterol esterification pathway in macrophages and Chinese hamster ovary cells. Biochemistry. 34: 10463-73. PMID 7654700 DOI: 10.1021/Bi00033A019  0.392
1995 van Weert AW, Dunn KW, Geuze HJ, Maxfield FR, Stoorvogel W. Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. The Journal of Cell Biology. 130: 821-34. PMID 7642700 DOI: 10.1083/Jcb.130.4.821  0.373
1995 Mayor S, Maxfield FR. Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Molecular Biology of the Cell. 6: 929-44. PMID 7579703 DOI: 10.1091/Mbc.6.7.929  0.561
1995 Lawson MA, Maxfield FR. Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature. 377: 75-9. PMID 7544874 DOI: 10.1038/377075A0  0.301
1995 Gruenberg J, Maxfield FR. Membrane transport in the endocytic pathway. Current Opinion in Cell Biology. 7: 552-63. PMID 7495576 DOI: 10.1016/0955-0674(95)80013-1  0.329
1994 Dunn KW, Mayor S, Myers JN, Maxfield FR. Applications of ratio fluorescence microscopy in the study of cell physiology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 8: 573-82. PMID 8005385 DOI: 10.1096/Fasebj.8.9.8005385  0.508
1994 Ghosh RN, Gelman DL, Maxfield FR. Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy. Journal of Cell Science. 107: 2177-89. PMID 7983176  0.302
1994 Mayor S, Rothberg KG, Maxfield FR. Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science (New York, N.Y.). 264: 1948-51. PMID 7516582 DOI: 10.1126/Science.7516582  0.535
1993 Mayor S, Presley JF, Maxfield FR. Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. The Journal of Cell Biology. 121: 1257-69. PMID 8509447 DOI: 10.1083/Jcb.121.6.1257  0.588
1993 McGraw TE, Dunn KW, Maxfield FR. Isolation of a temperature-sensitive variant Chinese hamster ovary cell line with a morphologically altered endocytic recycling compartment. Journal of Cellular Physiology. 155: 579-94. PMID 8491793 DOI: 10.1002/Jcp.1041550316  0.352
1993 Salzman NH, Maxfield FR. Quantitative fluorescence techniques for the characterization of endocytosis in intact cells. Sub-Cellular Biochemistry. 19: 95-123. PMID 8385822 DOI: 10.1007/978-1-4615-3026-8_4  0.307
1993 Presley JF, Mayor S, Dunn KW, Johnson LS, McGraw TE, Maxfield FR. The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected. The Journal of Cell Biology. 122: 1231-41. PMID 8376460 DOI: 10.1083/Jcb.122.6.1231  0.559
1993 Myers JN, Tabas I, Jones NL, Maxfield FR. Beta-very low density lipoprotein is sequestered in surface-connected tubules in mouse peritoneal macrophages. The Journal of Cell Biology. 123: 1389-402. PMID 8253839 DOI: 10.1083/Jcb.123.6.1389  0.336
1992 Dunn KW, Maxfield FR. Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes. The Journal of Cell Biology. 117: 301-10. PMID 1560027 DOI: 10.1083/Jcb.117.2.301  0.376
1992 Stins MF, Maxfield FR, Goldberg IJ. Polarized binding of lipoprotein lipase to endothelial cells. Implications for its physiological actions. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 12: 1437-46. PMID 1450176 DOI: 10.1161/01.Atv.12.12.1437  0.339
1991 Tabas I, Myers JN, Innerarity TL, Xu XX, Arnold K, Boyles J, Maxfield FR. The influence of particle size and multiple apoprotein E-receptor interactions on the endocytic targeting of beta-VLDL in mouse peritoneal macrophages. The Journal of Cell Biology. 115: 1547-60. PMID 1661729 DOI: 10.1083/Jcb.115.6.1547  0.318
1990 Tabas I, Lim S, Xu XX, Maxfield FR. Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages. The Journal of Cell Biology. 111: 929-40. PMID 2391369 DOI: 10.1083/Jcb.111.3.929  0.373
1990 Pytowski B, Maxfield FR, Michl J. Fc and C3bi receptors and the differentiation antigen BH2-Ag are randomly distributed in the plasma membrane of locomoting neutrophils. The Journal of Cell Biology. 110: 661-8. PMID 2137828 DOI: 10.1083/Jcb.110.3.661  0.348
1990 McGraw TE, Maxfield FR. Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain. Cell Regulation. 1: 369-77. PMID 2100204 DOI: 10.1091/Mbc.1.4.369  0.323
1989 Salzman NH, Maxfield FR. Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells. The Journal of Cell Biology. 109: 2097-104. PMID 2681226 DOI: 10.1083/Jcb.109.5.2097  0.327
1989 Dunn KW, McGraw TE, Maxfield FR. Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome. The Journal of Cell Biology. 109: 3303-14. PMID 2600137 DOI: 10.1083/Jcb.109.6.3303  0.386
1989 Yamashiro DJ, Borden LA, Maxfield FR. Kinetics of alpha 2-macroglobulin endocytosis and degradation in mutant and wild-type Chinese hamster ovary cells. Journal of Cellular Physiology. 139: 377-82. PMID 2469687 DOI: 10.1002/Jcp.1041390221  0.336
1988 McGraw TE, Dunn KW, Maxfield FR. Phorbol ester treatment increases the exocytic rate of the transferrin receptor recycling pathway independent of serine-24 phosphorylation. The Journal of Cell Biology. 106: 1061-6. PMID 3129437 DOI: 10.1083/Jcb.106.4.1061  0.353
1987 McGraw TE, Greenfield L, Maxfield FR. Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor. The Journal of Cell Biology. 105: 207-14. PMID 3611186 DOI: 10.1083/Jcb.105.1.207  0.337
1987 Maxfield FR, Yamashiro DJ. Endosome acidification and the pathways of receptor-mediated endocytosis. Advances in Experimental Medicine and Biology. 225: 189-98. PMID 2839960 DOI: 10.1007/978-1-4684-5442-0_16  0.322
1987 Yamashiro DJ, Maxfield FR. Acidification of morphologically distinct endosomes in mutant and wild-type Chinese hamster ovary cells. The Journal of Cell Biology. 105: 2723-33. PMID 2447098 DOI: 10.1083/Jcb.105.6.2723  0.361
1987 Yamashiro DJ, Maxfield FR. Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells. The Journal of Cell Biology. 105: 2713-21. PMID 2447097 DOI: 10.1083/Jcb.105.6.2713  0.342
1984 DiPaola M, Keith CH, Feldman D, Tycko B, Maxfield FR. Loss of alpha 2-macroglobulin and epidermal growth factor surface binding induced by phenothiazines and naphthalene sulfonamides. Journal of Cellular Physiology. 118: 193-202. PMID 6319437 DOI: 10.1002/Jcp.1041180212  0.585
1984 Yamashiro DJ, Tycko B, Fluss SR, Maxfield FR. Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell. 37: 789-800. PMID 6204769 DOI: 10.1016/0092-8674(84)90414-8  0.566
1984 Yamashiro DJ, Maxfield FR. Acidification of endocytic compartments and the intracellular pathways of ligands and receptors. Journal of Cellular Biochemistry. 26: 231-46. PMID 6085081 DOI: 10.1002/Jcb.240260404  0.358
1983 Tycko B, Keith CH, Maxfield FR. Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line. The Journal of Cell Biology. 97: 1762-76. PMID 6315742 DOI: 10.1083/Jcb.97.6.1762  0.582
1983 Yamashiro DJ, Fluss SR, Maxfield FR. Acidification of endocytic vesicles by an ATP-dependent proton pump. The Journal of Cell Biology. 97: 929-34. PMID 6224803 DOI: 10.1083/Jcb.97.3.929  0.359
1983 Tycko B, DiPaola M, Yamashiro DJ, Fluss S, Maxfield FR. Acidification of endocytic vesicles and the intracellular pathways of ligands and receptors. Annals of the New York Academy of Sciences. 421: 424-33. PMID 6202216 DOI: 10.1111/J.1749-6632.1983.Tb18136.X  0.545
1982 Maxfield FR. Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. The Journal of Cell Biology. 95: 676-81. PMID 6183281 DOI: 10.1083/Jcb.95.2.676  0.324
1982 Keen JH, Maxfield FR, Hardegree MC, Habig WH. Receptor-mediated endocytosis of diphtheria toxin by cells in culture. Proceedings of the National Academy of Sciences of the United States of America. 79: 2912-6. PMID 6178112 DOI: 10.1073/Pnas.79.9.2912  0.361
1982 Tycko B, Maxfield FR. Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell. 28: 643-51. PMID 6176331 DOI: 10.1016/0092-8674(82)90219-7  0.549
1982 Anderson P, Tycko B, Maxfield F, Vilček J. Effect of primary amines on interferon action Virology. 117: 510-515. PMID 6175094 DOI: 10.1016/0042-6822(82)90491-3  0.546
1981 Han SL, Stimson ER, Maxfield FR, Scheraga HA. Spectroscopic study of the conformations of proline-containing oligopeptides in the crystalline state and in solution. International Journal of Peptide and Protein Research. 17: 297-315. PMID 7287301 DOI: 10.1111/J.1399-3011.1981.Tb01996.X  0.395
1981 Maxfield FR, Willingham MC, Pastan I, Dragsten P, Cheng SY. Binding and mobility of the cell surface receptors for 3,3',5-triiodo-L-thyronine. Science (New York, N.Y.). 211: 63-5. PMID 6255563  0.375
1981 Maxfield FR, Willingham MC, Haigler HT, Dragsten P, Pastan IH. Binding, surface mobility, internalization, and degradation of rhodamine-labeled alpha 2-macroglobulin. Biochemistry. 20: 5353-8. PMID 6170323 DOI: 10.1021/Bi00521A041  0.439
1981 Maxfield FR, Bandekar J, Krimm S, Evans DJ, Leach SJ, Nemethy G, Scheraga HA. Conformation of cyclo(L-alanylglycyl-.epsilon.-aminocaproyl), a cyclized dipeptide model for a .beta. bend. 3. Infrared and Raman spectroscopic studies Macromolecules. 14: 997-1003. DOI: 10.1021/Ma50005A018  0.587
1981 Maxfield FR, Bandekar J, Krimm S, Evans DJ, Leach SJ, Nemethy G, Scheraga HA. Conformation of cyclo(L-alanylglycyl-ε-aminocaproyl), a cyclized dipeptide model for a β bend. 3. Infrared and Raman spectroscopic studies Macromolecules. 14: 997-1003.  0.473
1980 Han SL, Stimson ER, Maxfield FR, Leach SJ, Scheraga HA. Study of the state of ionization of [Leu5]-enkephalin in the crystal and in solution. International Journal of Peptide and Protein Research. 16: 183-90. PMID 7461900 DOI: 10.1111/J.1399-3011.1980.Tb02951.X  0.364
1980 Han SL, Stimson ER, Maxfield FR, Scheraga HA. Conformational study of [Leu5]-enkephalin by laser Raman spectroscopy. International Journal of Peptide and Protein Research. 16: 173-81. PMID 7461899 DOI: 10.1111/J.1399-3011.1980.Tb02950.X  0.379
1980 Haigler HT, Maxfield FR, Willingham MC, Pastan I. Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells. The Journal of Biological Chemistry. 255: 1239-41. PMID 6243633  0.382
1980 Willingham MC, Maxfield FR, Pastan I. Receptor-mediated endocytosis of alpha 2-macroglobulin in cultured fibroblasts. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 28: 818-23. PMID 6160180 DOI: 10.1177/28.8.6160180  0.473
1980 Cheng SY, Maxfield FR, Robbins J, Willingham MC, Pastan IH. Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 77: 3425-9. PMID 6158047 DOI: 10.1073/Pnas.77.6.3425  0.461
1980 Davies PJ, Davies DR, Levitzki A, Maxfield FR, Milhaud P, Willingham MC, Pastan IH. Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones. Nature. 283: 162-7. PMID 6153122 DOI: 10.1038/283162A0  0.443
1979 Deslauriers R, Leach SJ, Maxfield FR, Minasian E, McQuie JR, Meinwald YC, Némethy G, Pottle MS, Rae ID, Scheraga HA, Stimson ER, Van Nispen JW. Cyclized dipeptide model for a beta-bend. Proceedings of the National Academy of Sciences of the United States of America. 76: 2512-4. PMID 288041 DOI: 10.1073/Pnas.76.6.2512  0.39
1979 LeCam A, Maxfield F, Willingham M, Pastan I. Insulin stimulation of amino acid transport in isolated rat hepatocytes is independent of hormone internalization. Biochemical and Biophysical Research Communications. 88: 873-81. PMID 223575 DOI: 10.1016/0006-291X(79)91490-6  0.407
1979 Maxfield FR, Scheraga HA. Improvements in the prediction of protein backbone topography by reduction of statistical errors. Biochemistry. 18: 697-704. PMID 217422 DOI: 10.1021/Bi00571A023  0.351
1979 Willingham MC, Maxfield FR, Pastan IH. alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions. The Journal of Cell Biology. 82: 614-25. PMID 92473 DOI: 10.1083/Jcb.82.3.614  0.438
1979 Maxfield FR, Willingham MC, Davies PJ, Pastan I. Amines inhibit the clustering of alpha2-macroglobulin and EGF on the fibroblast cell surface. Nature. 277: 661-3. PMID 85262 DOI: 10.1038/277661A0  0.462
1979 Maxfield FR, Davies PJ, Klempner L, Willingham MC, Pastan I. Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits. Proceedings of the National Academy of Sciences of the United States of America. 76: 5731-5. PMID 42903 DOI: 10.1073/Pnas.76.11.5731  0.432
1979 Maxfield FR, Leach SJ, Stimson ER, Powers SP, Scheraga HA. Infrared spectra of theN-acetyl-N?-methylamides of glycine,L-alanine, andL-leucine in dilute solutions of chloroform and carbon tetrachloride Biopolymers. 18: 2507-2521. DOI: 10.1002/Bip.1979.360181010  0.372
1978 Maxfield FR, Schlessinger J, Shechter Y, Pastan I, Willingham MC. Collection of insulin, EGF and alpha2-macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization. Cell. 14: 805-10. PMID 80283 DOI: 10.1016/0092-8674(78)90336-7  0.436
1977 Maxfield FR, Scheraga HA. A Raman spectroscopic investigation of the disulfide conformation in oxytocin and lysine vasopressin. Biochemistry. 16: 4443-9. PMID 911768 DOI: 10.1021/Bi00639A018  0.364
1976 Maxfield FR, Scheraga HA. Status of empirical methods for the prediction of protein backbone topography. Biochemistry. 15: 5138-53. PMID 990270 DOI: 10.1021/Bi00668A030  0.383
1975 Maxfield FR, Scheraga HA. The effect of neighboring charges on the helix forming ability of charged amino acids in proteins. Macromolecules. 8: 491-3. PMID 1177494 DOI: 10.1021/Ma60046A022  0.384
1975 Maxfield FR, Alter JE, Taylor GT, Scheraga HA. Helix-coil stability constants for the naturally occurring amino acids in water. IX. Glutamic acid parameters from random poly(hydroxybutylglutamine-co-L-glutamic acid). Macromolecules. 8: 479-91. PMID 240987 DOI: 10.1021/Ma60046A021  0.386
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