Frederick R. Maxfield - Publications

Affiliations: 
Biochemistry Weill Cornell Medical College, New York, NY, United States 
Website:
http://weill.cornell.edu/research/frmaxfield/biography.html

216 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Solé-Domènech S, Rojas AV, Maisuradze GG, Scheraga HA, Lobel P, Maxfield FR. Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 29378960 DOI: 10.1073/pnas.1719808115  0.96
2016 Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, ... ... Maxfield FR, et al. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Science Translational Medicine. 8: 328ra29. PMID 26936506 DOI: 10.1126/scitranslmed.aac6008  1
2015 Iaea DB, Gale SE, Bielska AA, Krishnan K, Fujiwara H, Jiang H, Maxfield FR, Schlesinger PH, Covey DF, Schaffer JE, Ory DS. A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol. Journal of Lipid Research. PMID 26497473 DOI: 10.1194/jlr.D064287  1
2015 Haka AS, Singh RK, Grosheva I, Hoffner H, Capetillo-Zarate E, Chin HF, Anandasabapathy N, Maxfield FR. Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2092-103. PMID 26293468 DOI: 10.1161/ATVBAHA.115.305843  1
2015 Iaea DB, Dikiy I, Kiburu I, Eliezer D, Maxfield FR. STARD4 Membrane Interactions and Sterol Binding. Biochemistry. 54: 4623-36. PMID 26168008 DOI: 10.1021/acs.biochem.5b00618  1
2015 Praggastis M, Tortelli B, Zhang J, Fujiwara H, Sidhu R, Chacko A, Chen Z, Chung C, Lieberman AP, Sikora J, Davidson C, Walkley SU, Pipalia NH, Maxfield FR, Schaffer JE, et al. A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8091-106. PMID 26019327 DOI: 10.1523/JNEUROSCI.4173-14.2015  1
2015 Iaea DB, Maxfield FR. Cholesterol trafficking and distribution. Essays in Biochemistry. 57: 43-55. PMID 25658343 DOI: 10.1042/bse0570043  1
2015 Patel JZ, Nevalainen TJ, Savinainen JR, Adams Y, Laitinen T, Runyon RS, Vaara M, Ahenkorah S, Kaczor AA, Navia-Paldanius D, Gynther M, Aaltonen N, Joharapurkar AA, Jain MR, Haka AS, ... Maxfield FR, et al. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. Chemmedchem. 10: 253-65. PMID 25504894 DOI: 10.1002/cmdc.201402453  1
2015 Iaea DB, Mao S, Maxfield FR. Steroidogenic acute regulatory protein-related lipid transfer (START) proteins in non-vesicular cholesterol transport Cholesterol Transporters of the Start Domain Protein Family in Health and Disease: Start Proteins-Structure and Function. 173-188. DOI: 10.1007/978-1-4939-1112-7_8  1
2014 Maxfield FR. Role of endosomes and lysosomes in human disease. Cold Spring Harbor Perspectives in Biology. 6: a016931. PMID 24789821 DOI: 10.1101/cshperspect.a016931  1
2014 Nociari MM, Lehmann GL, Perez Bay AE, Radu RA, Jiang Z, Goicochea S, Schreiner R, Warren JD, Shan J, Adam de Beaumais S, Ménand M, Sollogoub M, Maxfield FR, Rodriguez-Boulan E. Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium. Proceedings of the National Academy of Sciences of the United States of America. 111: E1402-8. PMID 24706818 DOI: 10.1073/pnas.1400530111  1
2013 Xiong Y, Lee HJ, Mariko B, Lu YC, Dannenberg AJ, Haka AS, Maxfield FR, Camerer E, Proia RL, Hla T. Sphingosine kinases are not required for inflammatory responses in macrophages. The Journal of Biological Chemistry. 288: 32563-73. PMID 24081141 DOI: 10.1074/jbc.M113.483750  1
2013 Helquist P, Maxfield FR, Wiech NL, Wiest O. Treatment of Niemann--pick type C disease by histone deacetylase inhibitors. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 688-97. PMID 24048860 DOI: 10.1007/s13311-013-0217-2  1
2013 Haka AS, Grosheva I, Singh RK, Maxfield FR. Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1768-78. PMID 23702659 DOI: 10.1161/ATVBAHA.112.301109  1
2012 Tortorella LL, Pipalia NH, Mukherjee S, Pastan I, Fitzgerald D, Maxfield FR. Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary. Plos One. 7: e47320. PMID 23056628 DOI: 10.1371/journal.pone.0047320  1
2012 Garbarino J, Pan M, Chin HF, Lund FW, Maxfield FR, Breslow JL. STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC. Journal of Lipid Research. 53: 2716-25. PMID 23033213 DOI: 10.1194/jlr.M032227  1
2012 Haka AS, Potteaux S, Fraser H, Randolph GJ, Maxfield FR. Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy. Plos One. 7: e44823. PMID 23024767 DOI: 10.1371/journal.pone.0044823  1
2012 Jain M, Robinson BD, Scherr DS, Sterling J, Lee MM, Wysock J, Rubin MA, Maxfield FR, Zipfel WR, Webb WW, Mukherjee S. Multiphoton microscopy in the evaluation of human bladder biopsies. Archives of Pathology & Laboratory Medicine. 136: 517-26. PMID 22540300 DOI: 10.5858/arpa.2011-0147-OA  1
2012 Maxfield FR, Wüstner D. Analysis of cholesterol trafficking with fluorescent probes. Methods in Cell Biology. 108: 367-93. PMID 22325611 DOI: 10.1016/B978-0-12-386487-1.00017-1  1
2011 Mesmin B, Pipalia NH, Lund FW, Ramlall TF, Sokolov A, Eliezer D, Maxfield FR. STARD4 abundance regulates sterol transport and sensing. Molecular Biology of the Cell. 22: 4004-15. PMID 21900492 DOI: 10.1091/mbc.E11-04-0372  1
2011 Tewari AK, Shevchuk MM, Sterling J, Grover S, Herman M, Yadav R, Mudalair K, Srivastava A, Rubin MA, Zipfel WR, Maxfield FR, Xu C, Webb WW, Mukherjee S. Multiphoton microscopy for structure identification in human prostate and periprostatic tissue: implications in prostate cancer surgery. Bju International. 108: 1421-9. PMID 21443651 DOI: 10.1111/j.1464-410X.2011.10169.x  1
2011 Majumdar A, Capetillo-Zarate E, Cruz D, Gouras GK, Maxfield FR. Degradation of Alzheimer's amyloid fibrils by microglia requires delivery of ClC-7 to lysosomes. Molecular Biology of the Cell. 22: 1664-76. PMID 21441306 DOI: 10.1091/mbc.E10-09-0745  1
2011 Pipalia NH, Cosner CC, Huang A, Chatterjee A, Bourbon P, Farley N, Helquist P, Wiest O, Maxfield FR. Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 108: 5620-5. PMID 21436030 DOI: 10.1073/pnas.1014890108  1
2011 Pagler TA, Wang M, Mondal M, Murphy AJ, Westerterp M, Moore KJ, Maxfield FR, Tall AR. Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling. Circulation Research. 108: 194-200. PMID 21148432 DOI: 10.1161/CIRCRESAHA.110.228619  1
2011 Rosenbaum AI, Maxfield FR. Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches. Journal of Neurochemistry. 116: 789-95. PMID 20807315 DOI: 10.1111/j.1471-4159.2010.06976.x  1
2010 Rujoi M, Pipalia NH, Maxfield FR. Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells. Plos One. 5: e12788. PMID 20877719 DOI: 10.1371/journal.pone.0012788  1
2010 VanderVen BC, Hermetter A, Huang A, Maxfield FR, Russell DG, Yates RM. Development of a novel, cell-based chemical screen to identify inhibitors of intraphagosomal lipolysis in macrophages. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 751-60. PMID 20653015 DOI: 10.1002/cyto.a.20911  1
2010 Maxfield FR, van Meer G. Cholesterol, the central lipid of mammalian cells. Current Opinion in Cell Biology. 22: 422-9. PMID 20627678 DOI: 10.1016/j.ceb.2010.05.004  1
2010 Rosenbaum AI, Cosner CC, Mariani CJ, Maxfield FR, Wiest O, Helquist P. Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics. Journal of Medicinal Chemistry. 53: 5281-9. PMID 20557099 DOI: 10.1021/jm100499s  1
2010 Devlin C, Pipalia NH, Liao X, Schuchman EH, Maxfield FR, Tabas I. Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect. Traffic (Copenhagen, Denmark). 11: 601-15. PMID 20412078 DOI: 10.1111/j.1600-0854.2010.01046.x  1
2010 Rosenbaum AI, Zhang G, Warren JD, Maxfield FR. Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 5477-82. PMID 20212119 DOI: 10.1073/pnas.0914309107  1
2009 Haka AS, Grosheva I, Chiang E, Buxbaum AR, Baird BA, Pierini LM, Maxfield FR. Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins. Molecular Biology of the Cell. 20: 4932-40. PMID 19812252 DOI: 10.1091/mbc.E09-07-0559  1
2009 Cosner CC, Markiewicz JT, Bourbon P, Mariani CJ, Wiest O, Rujoi M, Rosenbaum AI, Huang AY, Maxfield FR, Helquist P. Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics. Journal of Medicinal Chemistry. 52: 6494-8. PMID 19772346 DOI: 10.1021/jm900707n  1
2009 Rosenbaum AI, Rujoi M, Huang AY, Du H, Grabowski GA, Maxfield FR. Chemical screen to reduce sterol accumulation in Niemann-Pick C disease cells identifies novel lysosomal acid lipase inhibitors. Biochimica Et Biophysica Acta. 1791: 1155-65. PMID 19699313 DOI: 10.1016/j.bbalip.2009.08.005  1
2009 Grosheva I, Haka AS, Qin C, Pierini LM, Maxfield FR. Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1615-21. PMID 19556523 DOI: 10.1161/ATVBAHA.109.191882  1
2009 Yadav R, Mukherjee S, Hermen M, Tan G, Maxfield FR, Webb WW, Tewari AK. Multiphoton microscopy of prostate and periprostatic neural tissue: a promising imaging technique for improving nerve-sparing prostatectomy. Journal of Endourology / Endourological Society. 23: 861-7. PMID 19425823 DOI: 10.1089/end.2009.0221  1
2009 Mukherjee S, Wysock JS, Ng CK, Akhtar M, Perner S, Lee MM, Rubin MA, Maxfield FR, Webb WW, Scherr DS. Human bladder cancer diagnosis using Multiphoton microscopy. Proceedings of Spie--the International Society For Optical Engineering. 7161. PMID 19360140 DOI: 10.1117/12.808314  1
2009 Mesmin B, Maxfield FR. Intracellular sterol dynamics. Biochimica Et Biophysica Acta. 1791: 636-45. PMID 19286471 DOI: 10.1016/j.bbalip.2009.03.002  1
2009 Mondal M, Mesmin B, Mukherjee S, Maxfield FR. Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells. Molecular Biology of the Cell. 20: 581-8. PMID 19019985 DOI: 10.1091/mbc.E08-07-0785  1
2008 Adachi S, Nagao T, To S, Joe AK, Shimizu M, Matsushima-Nishiwaki R, Kozawa O, Moriwaki H, Maxfield FR, Weinstein IB. (-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells. Carcinogenesis. 29: 1986-93. PMID 18586691 DOI: 10.1093/carcin/bgn128  1
2008 Pan M, Maitin V, Parathath S, Andreo U, Lin SX, St Germain C, Yao Z, Maxfield FR, Williams KJ, Fisher EA. Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for late-stage quality control. Proceedings of the National Academy of Sciences of the United States of America. 105: 5862-7. PMID 18391222 DOI: 10.1073/pnas.0707460104  1
2008 Ding T, Li Z, Hailemariam T, Mukherjee S, Maxfield FR, Wu MP, Jiang XC. SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis. Journal of Lipid Research. 49: 376-85. PMID 17982138 DOI: 10.1194/jlr.M700401-JLR200  1
2008 Majumdar A, Chung H, Dolios G, Wang R, Asamoah N, Lobel P, Maxfield FR. Degradation of fibrillar forms of Alzheimer's amyloid beta-peptide by macrophages. Neurobiology of Aging. 29: 707-15. PMID 17222479 DOI: 10.1016/j.neurobiolaging.2006.12.001  1
2007 Adachi S, Nagao T, Ingolfsson HI, Maxfield FR, Andersen OS, Kopelovich L, Weinstein IB. The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells. Cancer Research. 67: 6493-501. PMID 17616711 DOI: 10.1158/0008-5472.CAN-07-0411  1
2007 Nagao T, Qin C, Grosheva I, Maxfield FR, Pierini LM. Elevated cholesterol levels in the plasma membranes of macrophages inhibit migration by disrupting RhoA regulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1596-602. PMID 17495238 DOI: 10.1161/ATVBAHA.107.145086  1
2007 Tortorella LL, Schapiro FB, Maxfield FR. Role of an acidic cluster/dileucine motif in cation-independent mannose 6-phosphate receptor traffic. Traffic (Copenhagen, Denmark). 8: 402-13. PMID 17319895 DOI: 10.1111/j.1600-0854.2007.00541.x  1
2007 Majumdar A, Cruz D, Asamoah N, Buxbaum A, Sohar I, Lobel P, Maxfield FR. Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils. Molecular Biology of the Cell. 18: 1490-6. PMID 17314396 DOI: 10.1091/mbc.E06-10-0975  1
2007 Pipalia NH, Hao M, Mukherjee S, Maxfield FR. Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect. Traffic (Copenhagen, Denmark). 8: 130-41. PMID 17156101 DOI: 10.1111/j.1600-0854.2006.00513.x  1
2006 Walczak W, Pipalia NH, Soni M, Faruqi AF, Ralph H, Maxfield FR, Webb BL. Parallel analysis of v-Src mutant protein function using reverse transfection cell arrays. Combinatorial Chemistry & High Throughput Screening. 9: 711-8. PMID 17100576 DOI: 10.2174/138620706778700116  1
2006 Murcia M, Faráldo-Gómez JD, Maxfield FR, Roux B. Modeling the structure of the StART domains of MLN64 and StAR proteins in complex with cholesterol. Journal of Lipid Research. 47: 2614-30. PMID 16990645 DOI: 10.1194/jlr.M600232-JLR200  1
2006 Maxfield FR, Menon AK. Intracellular sterol transport and distribution. Current Opinion in Cell Biology. 18: 379-85. PMID 16806879 DOI: 10.1016/j.ceb.2006.06.012  1
2006 Maxfield FR, Mondal M. Sterol and lipid trafficking in mammalian cells. Biochemical Society Transactions. 34: 335-9. PMID 16709155 DOI: 10.1042/BST0340335  1
2006 Liang XJ, Mukherjee S, Shen DW, Maxfield FR, Gottesman MM. Endocytic recycling compartments altered in cisplatin-resistant cancer cells. Cancer Research. 66: 2346-53. PMID 16489040 DOI: 10.1158/0008-5472.CAN-05-3436  1
2006 Qin C, Nagao T, Grosheva I, Maxfield FR, Pierini LM. Elevated plasma membrane cholesterol content alters macrophage signaling and function. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 372-8. PMID 16306428 DOI: 10.1161/01.ATV.0000197848.67999.e1  1
2006 Pipalia NH, Huang A, Ralph H, Rujoi M, Maxfield FR. Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells. Journal of Lipid Research. 47: 284-301. PMID 16288097 DOI: 10.1194/jlr.M500388-JLR200  1
2005 Maxfield FR, Tabas I. Role of cholesterol and lipid organization in disease. Nature. 438: 612-21. PMID 16319881 DOI: 10.1038/nature04399  1
2005 Wüstner D, Mondal M, Tabas I, Maxfield FR. Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells. Traffic (Copenhagen, Denmark). 6: 396-412. PMID 15813750 DOI: 10.1111/j.1600-0854.2005.00285.x  1
2004 Mukherjee S, Maxfield FR. Membrane domains. Annual Review of Cell and Developmental Biology. 20: 839-66. PMID 15473862 DOI: 10.1146/annurev.cellbio.20.010403.095451  1
2004 Mukherjee S, Maxfield FR. Lipid and cholesterol trafficking in NPC. Biochimica Et Biophysica Acta. 1685: 28-37. PMID 15465424 DOI: 10.1016/j.bbalip.2004.08.009  1
2004 Lin SX, Maxfield FR. Fluorescence imaging in living animals. Focus on "Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy". American Journal of Physiology. Cell Physiology. 287: C257-9. PMID 15238357 DOI: 10.1152/ajpcell.00235.2004  1
2004 Li Y, Ge M, Ciani L, Kuriakose G, Westover EJ, Dura M, Covey DF, Freed JH, Maxfield FR, Lytton J, Tabas I. Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages. The Journal of Biological Chemistry. 279: 37030-9. PMID 15215242 DOI: 10.1074/jbc.M405195200  1
2004 Schapiro FB, Soe TT, Mallet WG, Maxfield FR. Role of cytoplasmic domain serines in intracellular trafficking of furin. Molecular Biology of the Cell. 15: 2884-94. PMID 15075375 DOI: 10.1091/mbc.E03-09-0653  1
2004 Recht PA, Tepedino GJ, Siecke NW, Buckley MT, Mandeville JT, Maxfield FR, Levin RI. Oxalic acid alters intracellular calcium in endothelial cells. Atherosclerosis. 173: 321-8. PMID 15064109 DOI: 10.1016/j.atherosclerosis.2003.11.023  1
2004 Maxfield FR, McGraw TE. Endocytic recycling. Nature Reviews. Molecular Cell Biology. 5: 121-32. PMID 15040445 DOI: 10.1038/nrm1315  1
2004 Hao M, Mukherjee S, Sun Y, Maxfield FR. Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes. The Journal of Biological Chemistry. 279: 14171-8. PMID 14734557 DOI: 10.1074/jbc.M309793200  1
2004 Wüstner D, Mondal M, Huang A, Maxfield FR. Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells. Journal of Lipid Research. 45: 427-37. PMID 14679167 DOI: 10.1194/jlr.M300440-JLR200  1
2004 Lin SX, Mallet WG, Huang AY, Maxfield FR. Endocytosed cation-independent mannose 6-phosphate receptor traffics via the endocytic recycling compartment en route to the trans-Golgi network and a subpopulation of late endosomes. Molecular Biology of the Cell. 15: 721-33. PMID 14595110 DOI: 10.1091/mbc.E03-07-0497  1
2003 Pierini LM, Maxfield FR. Optical microscopy-based migration assay for human neutrophils. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 12.6. PMID 18228419 DOI: 10.1002/0471143030.cb1206s17  1
2003 Dunn K, Maxfield FR. Ratio imaging instrumentation. Methods in Cell Biology. 72: 389-413. PMID 14719342  1
2003 Patel M, Morrow J, Maxfield FR, Strickland DK, Greenberg S, Tabas I. The cytoplasmic domain of the low density lipoprotein (LDL) receptor-related protein, but not that of the LDL receptor, triggers phagocytosis. The Journal of Biological Chemistry. 278: 44799-807. PMID 12941948 DOI: 10.1074/jbc.M308982200  1
2003 Mamdouh Z, Chen X, Pierini LM, Maxfield FR, Muller WA. Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis. Nature. 421: 748-53. PMID 12610627 DOI: 10.1038/nature01300  1
2003 Pierini LM, Eddy RJ, Fuortes M, Seveau S, Casulo C, Maxfield FR. Membrane lipid organization is critical for human neutrophil polarization. The Journal of Biological Chemistry. 278: 10831-41. PMID 12522144 DOI: 10.1074/jbc.M212386200  1
2003 Sun Y, Hao M, Luo Y, Liang CP, Silver DL, Cheng C, Maxfield FR, Tall AR. Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure. The Journal of Biological Chemistry. 278: 5813-20. PMID 12482877 DOI: 10.1074/jbc.M208687200  1
2002 Eddy RJ, Pierini LM, Maxfield FR. Microtubule asymmetry during neutrophil polarization and migration. Molecular Biology of the Cell. 13: 4470-83. PMID 12475966 DOI: 10.1091/mbc.E02-04-0241  1
2002 Maxfield FR. Plasma membrane microdomains. Current Opinion in Cell Biology. 14: 483-7. PMID 12383800 DOI: 10.1016/S0955-0674(02)00351-4  1
2002 Maxfield FR, Wüstner D. Intracellular cholesterol transport. The Journal of Clinical Investigation. 110: 891-8. PMID 12370264 DOI: 10.1172/JCI16500  1
2002 Wüstner D, Herrmann A, Hao M, Maxfield FR. Rapid nonvesicular transport of sterol between the plasma membrane domains of polarized hepatic cells. The Journal of Biological Chemistry. 277: 30325-36. PMID 12050151 DOI: 10.1074/jbc.M202626200  1
2002 Lin SX, Gundersen GG, Maxfield FR. Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin. Molecular Biology of the Cell. 13: 96-109. PMID 11809825 DOI: 10.1091/mbc.01-05-0224  1
2002 Hao M, Lin SX, Karylowski OJ, Wüstner D, McGraw TE, Maxfield FR. Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle. The Journal of Biological Chemistry. 277: 609-17. PMID 11682487 DOI: 10.1074/jbc.M108861200  1
2001 Hao M, Mukherjee S, Maxfield FR. Cholesterol depletion induces large scale domain segregation in living cell membranes. Proceedings of the National Academy of Sciences of the United States of America. 98: 13072-7. PMID 11698680 DOI: 10.1073/pnas.231377398  1
2001 Seveau S, Eddy RJ, Maxfield FR, Pierini LM. Cytoskeleton-dependent membrane domain segregation during neutrophil polarization. Molecular Biology of the Cell. 12: 3550-62. PMID 11694588  1
2001 Bennett EM, Lin SX, Towler MC, Maxfield FR, Brodsky FM. Clathrin hub expression affects early endosome distribution with minimal impact on receptor sorting and recycling. Molecular Biology of the Cell. 12: 2790-9. PMID 11553717  1
2001 Pierini LM, Maxfield FR. Flotillas of lipid rafts fore and aft. Proceedings of the National Academy of Sciences of the United States of America. 98: 9471-3. PMID 11504934 DOI: 10.1073/pnas.181353098  1
2001 Sakr SW, Eddy RJ, Barth H, Wang F, Greenberg S, Maxfield FR, Tabas I. The uptake and degradation of matrix-bound lipoproteins by macrophages require an intact actin Cytoskeleton, Rho family GTPases, and myosin ATPase activity. The Journal of Biological Chemistry. 276: 37649-58. PMID 11477084 DOI: 10.1074/jbc.M105129200  1
2001 Khelef N, Shuman HA, Maxfield FR. Phagocytosis of wild-type Legionella pneumophila occurs through a wortmannin-insensitive pathway. Infection and Immunity. 69: 5157-61. PMID 11447198 DOI: 10.1128/IAI.69.8.5157-5161.2001  1
2001 Matyash V, Geier C, Henske A, Mukherjee S, Hirsh D, Thiele C, Grant B, Maxfield FR, Kurzchalia TV. Distribution and transport of cholesterol in Caenorhabditis elegans. Molecular Biology of the Cell. 12: 1725-36. PMID 11408580  1
2001 Lin SX, Grant B, Hirsh D, Maxfield FR. Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells. Nature Cell Biology. 3: 567-72. PMID 11389441 DOI: 10.1038/35078543  1
2001 Chung H, Brazil MI, Irizarry MC, Hyman BT, Maxfield FR. Uptake of fibrillar beta-amyloid by microglia isolated from MSR-A (type I and type II) knockout mice. Neuroreport. 12: 1151-4. PMID 11338182  1
2001 Wüstner D, Mukherjee S, Maxfield FR, Müller P, Herrmann A. Vesicular and nonvesicular transport of phosphatidylcholine in polarized HepG2 cells. Traffic (Copenhagen, Denmark). 2: 277-96. PMID 11285138 DOI: 10.1046/j.1398-9219.2001.00009.x  1
2001 Hao M, Maxfield FR. Analyzing microdomains in biological membranes using fluorescence techniques Journal of Fluorescence. 11: 287-295.  1
2000 Mukherjee S, Maxfield FR. Role of membrane organization and membrane domains in endocytic lipid trafficking. Traffic (Copenhagen, Denmark). 1: 203-11. PMID 11208103  1
2000 Mallet WG, Maxfield FR. Endocytosis. Advances in Nephrology From the Necker Hospital. 30: 109-25. PMID 11068638  1
2000 Khelef N, Soe TT, Quehenberger O, Beatini N, Tabas I, Maxfield FR. Enrichment of acyl coenzyme A:cholesterol O-acyltransferase near trans-golgi network and endocytic recycling compartment. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1769-76. PMID 10894815  1
2000 Hao M, Maxfield FR. Characterization of rapid membrane internalization and recycling. The Journal of Biological Chemistry. 275: 15279-86. PMID 10809763 DOI: 10.1074/jbc.275.20.15279  1
2000 Pierini LM, Lawson MA, Eddy RJ, Hendey B, Maxfield FR. Oriented endocytic recycling of alpha5beta1 in motile neutrophils. Blood. 95: 2471-80. PMID 10753823  1
2000 Seveau S, Keller H, Maxfield FR, Piller F, Halbwachs-Mecarelli L. Neutrophil polarity and locomotion are associated with surface redistribution of leukosialin (CD43), an antiadhesive membrane molecule. Blood. 95: 2462-70. PMID 10753822  1
2000 Brazil MI, Chung H, Maxfield FR. Effects of incorporation of immunoglobulin G and complement component C1q on uptake and degradation of Alzheimer's disease amyloid fibrils by microglia. The Journal of Biological Chemistry. 275: 16941-7. PMID 10747968 DOI: 10.1074/jbc.M000937200  1
2000 Eddy RJ, Pierini LM, Matsumura F, Maxfield FR. Ca2+-dependent myosin II activation is required for uropod retraction during neutrophil migration. Journal of Cell Science. 113: 1287-98. PMID 10704379  1
1999 Mukherjee S, Maxfield FR. Cholesterol: stuck in traffic. Nature Cell Biology. 1: E37-8. PMID 10559892 DOI: 10.1038/10030  1
1999 Chung H, Brazil MI, Soe TT, Maxfield FR. Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. The Journal of Biological Chemistry. 274: 32301-8. PMID 10542270 DOI: 10.1074/jbc.274.45.32301  1
1999 Buton X, Mamdouh Z, Ghosh R, Du H, Kuriakose G, Beatini N, Grabowski GA, Maxfield FR, Tabas I. Unique cellular events occurring during the initial interaction of macrophages with matrix-retained or methylated aggregated low density lipoprotein (LDL). Prolonged cell-surface contact during which ldl-cholesteryl ester hydrolysis exceeds ldl protein degradation. The Journal of Biological Chemistry. 274: 32112-21. PMID 10542246 DOI: 10.1074/jbc.274.45.32112  1
1999 Mallet WG, Maxfield FR. Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways. The Journal of Cell Biology. 146: 345-59. PMID 10465644 DOI: 10.1083/jcb.146.2.345  1
1999 Mukherjee S, Soe TT, Maxfield FR. Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails. The Journal of Cell Biology. 144: 1271-84. PMID 10087269 DOI: 10.1083/jcb.144.6.1271  1
1998 Mukherjee S, Zha X, Tabas I, Maxfield FR. Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Biophysical Journal. 75: 1915-25. PMID 9746532 DOI: 10.1016/S0006-3495(98)77632-5  1
1998 Ghosh RN, Mallet WG, Soe TT, McGraw TE, Maxfield FR. An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells. The Journal of Cell Biology. 142: 923-36. PMID 9722606 DOI: 10.1083/jcb.142.4.923  1
1998 Wiater LA, Dunn K, Maxfield FR, Shuman HA. Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila. Infection and Immunity. 66: 4450-60. PMID 9712800  1
1998 Mayor S, Sabharanjak S, Maxfield FR. Cholesterol-dependent retention of GPI-anchored proteins in endosomes. The Embo Journal. 17: 4626-38. PMID 9707422 DOI: 10.1093/emboj/17.16.4626  1
1998 Khelef N, Buton X, Beatini N, Wang H, Meiner V, Chang TY, Farese RV, Maxfield FR, Tabas I. Immunolocalization of acyl-coenzyme A:cholesterol O-acyltransferase in macrophages. The Journal of Biological Chemistry. 273: 11218-24. PMID 9556612 DOI: 10.1074/jbc.273.18.11218  1
1998 Dunn K, Maxfield FR. Ratio imaging instrumentation. Methods in Cell Biology. 56: 217-36. PMID 9500140  1
1998 Zha X, Pierini LM, Leopold PL, Skiba PJ, Tabas I, Maxfield FR. Sphingomyelinase treatment induces ATP-independent endocytosis. The Journal of Cell Biology. 140: 39-47. PMID 9425152 DOI: 10.1083/jcb.140.1.39  1
1997 Paresce DM, Chung H, Maxfield FR. Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells. The Journal of Biological Chemistry. 272: 29390-7. PMID 9361021 DOI: 10.1074/jbc.272.46.29390  1
1997 Zha X, Tabas I, Leopold PL, Jones NL, Maxfield FR. Evidence for prolonged cell-surface contact of acetyl-LDL before entry into macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1421-31. PMID 9261276  1
1997 Mukherjee S, Ghosh RN, Maxfield FR. Endocytosis. Physiological Reviews. 77: 759-803. PMID 9234965  1
1997 Maxfield FR, Mayor S. Cell surface dynamics of GPI-anchored proteins. Advances in Experimental Medicine and Biology. 419: 355-64. PMID 9193677  1
1997 Presley JF, Mayor S, McGraw TE, Dunn KW, Maxfield FR. Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling. The Journal of Biological Chemistry. 272: 13929-36. PMID 9153255 DOI: 10.1074/jbc.272.21.13929  1
1997 Mandeville JT, Maxfield FR. Effects of buffering intracellular free calcium on neutrophil migration through three-dimensional matrices. Journal of Cellular Physiology. 171: 168-78. PMID 9130464 DOI: 10.1002/(SICI)1097-4652(199705)171:2<168::AID-JCP7>3.0.CO;2-M  1
1997 Mandeville JT, Lawson MA, Maxfield FR. Dynamic imaging of neutrophil migration in three dimensions: mechanical interactions between cells and matrix. Journal of Leukocyte Biology. 61: 188-200. PMID 9021925  1
1996 Mandeville JT, Maxfield FR. Calcium and signal transduction in granulocytes. Current Opinion in Hematology. 3: 63-70. PMID 9372053  1
1996 Johnson AO, Ghosh RN, Dunn KW, Garippa R, Park J, Mayor S, Maxfield FR, McGraw TE. Transferrin receptor containing the SDYQRL motif of TGN38 causes a reorganization of the recycling compartment but is not targeted to the TGN. The Journal of Cell Biology. 135: 1749-62. PMID 8991088 DOI: 10.1083/jcb.135.6.1749  1
1996 Paresce DM, Ghosh RN, Maxfield FR. Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron. 17: 553-65. PMID 8816718 DOI: 10.1016/S0896-6273(00)80187-7  1
1996 Skiba PJ, Zha X, Maxfield FR, Schissel SL, Tabas I. The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent. The Journal of Biological Chemistry. 271: 13392-400. PMID 8662777 DOI: 10.1074/jbc.271.23.13392  1
1996 Hendey B, Lawson M, Marcantonio EE, Maxfield FR. Intracellular calcium and calcineurin regulate neutrophil motility on vitronectin through a receptor identified by antibodies to integrins alphav and beta3. Blood. 87: 2038-48. PMID 8634455  1
1996 Maxfield FR, Sturlev SL. Endogenously expressed apoprotein e3 (apoe) has constrasting effects on cell lipid metabolism to exogenously derived apo e y Faseb Journal. 10: A722.  1
1995 Ghosh RN, Maxfield FR. Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells. The Journal of Cell Biology. 128: 549-61. PMID 7860630 DOI: 10.1083/jcb.128.4.549  1
1995 Schwiegelshohn B, Presley JF, Gorecki M, Vogel T, Carpentier YA, Maxfield FR, Deckelbaum RJ. Effects of apoprotein E on intracellular metabolism of model triglyceride-rich particles are distinct from effects on cell particle uptake. The Journal of Biological Chemistry. 270: 1761-9. PMID 7829512  1
1995 Marsh EW, Leopold PL, Jones NL, Maxfield FR. Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. The Journal of Cell Biology. 129: 1509-22. PMID 7790351 DOI: 10.1083/jcb.129.6.1509  1
1995 Mandeville JT, Ghosh RN, Maxfield FR. Intracellular calcium levels correlate with speed and persistent forward motion in migrating neutrophils. Biophysical Journal. 68: 1207-17. PMID 7787012 DOI: 10.1016/S0006-3495(95)80336-X  1
1995 Loike JD, el Khoury J, Cao L, Richards CP, Rascoff H, Mandeville JT, Maxfield FR, Silverstein SC. Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl-phenylalanine. The Journal of Experimental Medicine. 181: 1763-72. PMID 7722453  1
1995 van Weert AW, Dunn KW, Geuze HJ, Maxfield FR, Stoorvogel W. Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. The Journal of Cell Biology. 130: 821-34. PMID 7642700 DOI: 10.1083/jcb.130.4.821  1
1995 Mayor S, Maxfield FR. Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Molecular Biology of the Cell. 6: 929-44. PMID 7579703  1
1995 Lawson MA, Maxfield FR. Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature. 377: 75-9. PMID 7544874 DOI: 10.1038/377075a0  1
1995 Gruenberg J, Maxfield FR. Membrane transport in the endocytic pathway. Current Opinion in Cell Biology. 7: 552-63. PMID 7495576 DOI: 10.1016/0955-0674(95)80013-1  1
1994 Fagotto F, Maxfield FR. Yolk platelets in Xenopus oocytes maintain an acidic internal pH which may be essential for sodium accumulation. The Journal of Cell Biology. 125: 1047-56. PMID 8195288 DOI: 10.1083/jcb.125.5.1047  1
1994 Tabas I, Zha X, Beatini N, Myers JN, Maxfield FR. The actin cytoskeleton is important for the stimulation of cholesterol esterification by atherogenic lipoproteins in macrophages. The Journal of Biological Chemistry. 269: 22547-56. PMID 8077203  1
1994 Dunn KW, Mayor S, Myers JN, Maxfield FR. Applications of ratio fluorescence microscopy in the study of cell physiology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 8: 573-82. PMID 8005385  1
1994 Maxfield FR. Introduction: optical microscopy in physiological investigations. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 8: 571-2. PMID 8005384  1
1994 Ghosh RN, Gelman DL, Maxfield FR. Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy. Journal of Cell Science. 107: 2177-89. PMID 7983176  1
1994 Fagotto F, Maxfield FR. Changes in yolk platelet pH during Xenopus laevis development correlate with yolk utilization. A quantitative confocal microscopy study. Journal of Cell Science. 107: 3325-37. PMID 7706389  1
1994 Mayor S, Rothberg KG, Maxfield FR. Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science (New York, N.Y.). 264: 1948-51. PMID 7516582  1
1993 Maxfield FR. Regulation of leukocyte locomotion by Ca2+. Trends in Cell Biology. 3: 386-91. PMID 14731656 DOI: 10.1016/0962-8924(93)90088-I  1
1993 Mayor S, Presley JF, Maxfield FR. Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. The Journal of Cell Biology. 121: 1257-69. PMID 8509447  1
1993 McGraw TE, Dunn KW, Maxfield FR. Isolation of a temperature-sensitive variant Chinese hamster ovary cell line with a morphologically altered endocytic recycling compartment. Journal of Cellular Physiology. 155: 579-94. PMID 8491793 DOI: 10.1002/jcp.1041550316  1
1993 Salzman NH, Maxfield FR. Quantitative fluorescence techniques for the characterization of endocytosis in intact cells. Sub-Cellular Biochemistry. 19: 95-123. PMID 8385822  1
1993 Presley JF, Mayor S, Dunn KW, Johnson LS, McGraw TE, Maxfield FR. The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected. The Journal of Cell Biology. 122: 1231-41. PMID 8376460  1
1993 Myers JN, Tabas I, Jones NL, Maxfield FR. Beta-very low density lipoprotein is sequestered in surface-connected tubules in mouse peritoneal macrophages. The Journal of Cell Biology. 123: 1389-402. PMID 8253839  1
1993 Augenbraun E, Maxfield FR, St Jules R, Setlik W, Holtzman E. Properties of acidified compartments in hippocampal neurons. European Journal of Cell Biology. 61: 34-43. PMID 8223706  1
1993 Hendey B, Maxfield FR. Regulation of neutrophil motility and adhesion by intracellular calcium transients. Blood Cells. 19: 143-61; discussion 1. PMID 7691266  1
1992 Dunn KW, Maxfield FR. Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes. The Journal of Cell Biology. 117: 301-10. PMID 1560027  1
1992 Borden LA, Maxfield FR, Goldman JE, Shelanski ML. Resting [Ca2+]i and [Ca2+]i transients are similar in fibroblasts from normal and Alzheimer's donors. Neurobiology of Aging. 13: 33-8. PMID 1542378 DOI: 10.1016/0197-4580(92)90005-I  1
1992 Stins MF, Maxfield FR, Goldberg IJ. Polarized binding of lipoprotein lipase to endothelial cells. Implications for its physiological actions. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 12: 1437-46. PMID 1450176  1
1992 Hendey B, Klee CB, Maxfield FR. Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. Science (New York, N.Y.). 258: 296-9. PMID 1384129  1
1991 Bush AB, Borden LA, Greene LA, Maxfield FR. Nerve growth factor potentiates bradykinin-induced calcium influx and release in PC12 cells. Journal of Neurochemistry. 57: 562-74. PMID 2072102  1
1991 Marks PW, Maxfield FR. Preparation of solutions with free calcium concentration in the nanomolar range using 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid. Analytical Biochemistry. 193: 61-71. PMID 1904204 DOI: 10.1016/0003-2697(91)90044-T  1
1991 Hussain MM, Maxfield FR, Más-Oliva J, Tabas I, Ji ZS, Innerarity TL, Mahley RW. Clearance of chylomicron remnants by the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. The Journal of Biological Chemistry. 266: 13936-40. PMID 1713211  1
1991 Marks PW, Hendey B, Maxfield FR. Attachment to fibronectin or vitronectin makes human neutrophil migration sensitive to alterations in cytosolic free calcium concentration. The Journal of Cell Biology. 112: 149-58. PMID 1702443  1
1991 Tabas I, Myers JN, Innerarity TL, Xu XX, Arnold K, Boyles J, Maxfield FR. The influence of particle size and multiple apoprotein E-receptor interactions on the endocytic targeting of beta-VLDL in mouse peritoneal macrophages. The Journal of Cell Biology. 115: 1547-60. PMID 1661729  1
1990 Tabas I, Lim S, Xu XX, Maxfield FR. Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages. The Journal of Cell Biology. 111: 929-40. PMID 2391369  1
1990 Marks PW, Maxfield FR. Local and global changes in cytosolic free calcium in neutrophils during chemotaxis and phagocytosis. Cell Calcium. 11: 181-90. PMID 2354498 DOI: 10.1016/0143-4160(90)90069-7  1
1990 Marks PW, Maxfield FR. Transient increases in cytosolic free calcium appear to be required for the migration of adherent human neutrophils. The Journal of Cell Biology. 110: 43-52. PMID 2295684  1
1990 Borden LA, Einstein R, Gabel CA, Maxfield FR. Acidification-dependent dissociation of endocytosed insulin precedes that of endocytosed proteins bearing the mannose 6-phosphate recognition marker. The Journal of Biological Chemistry. 265: 8497-504. PMID 2160460  1
1990 Pytowski B, Maxfield FR, Michl J. Fc and C3bi receptors and the differentiation antigen BH2-Ag are randomly distributed in the plasma membrane of locomoting neutrophils. The Journal of Cell Biology. 110: 661-8. PMID 2137828  1
1990 McGraw TE, Maxfield FR. Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain. Cell Regulation. 1: 369-77. PMID 2100204  1
1989 Maxfield FR. Measurement of vacuolar pH and cytoplasmic calcium in living cells using fluorescence microscopy. Methods in Enzymology. 173: 745-71. PMID 2779443  1
1989 Salzman NH, Maxfield FR. Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells. The Journal of Cell Biology. 109: 2097-104. PMID 2681226  1
1989 Dunn KW, McGraw TE, Maxfield FR. Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome. The Journal of Cell Biology. 109: 3303-14. PMID 2600137 DOI: 10.1083/jcb.109.6.3303  1
1989 Maxfield FR. Fluorescent analogs of peptides and hormones. Methods in Cell Biology. 29: 13-28. PMID 2536460  1
1989 Yamashiro DJ, Borden LA, Maxfield FR. Kinetics of alpha 2-macroglobulin endocytosis and degradation in mutant and wild-type Chinese hamster ovary cells. Journal of Cellular Physiology. 139: 377-82. PMID 2469687 DOI: 10.1002/jcp.1041390221  1
1988 Ratan RR, Maxfield FR, Shelanski ML. Long-lasting and rapid calcium changes during mitosis. The Journal of Cell Biology. 107: 993-9. PMID 3417787  1
1988 Salzman NH, Maxfield FR. Intracellular fusion of sequentially formed endocytic compartments. The Journal of Cell Biology. 106: 1083-91. PMID 3360848  1
1988 Marks PW, Kruskal BA, Maxfield FR. Simultaneous addition of EGF prolongs the increase in cytosolic free calcium seen in response to bradykinin in NRK-49F cells. Journal of Cellular Physiology. 136: 519-25. PMID 3262620 DOI: 10.1002/jcp.1041360318  1
1988 McGraw TE, Dunn KW, Maxfield FR. Phorbol ester treatment increases the exocytic rate of the transferrin receptor recycling pathway independent of serine-24 phosphorylation. The Journal of Cell Biology. 106: 1061-6. PMID 3129437  1
1988 Yamashiro DJ, Maxfield FR. Regulation of endocytic processes by pH. Trends in Pharmacological Sciences. 9: 190-3. PMID 3073552 DOI: 10.1016/0165-6147(88)90078-8  1
1987 Kruskal BA, Maxfield FR. Cytosolic free calcium increases before and oscillates during frustrated phagocytosis in macrophages. The Journal of Cell Biology. 105: 2685-93. PMID 3693396  1
1987 McGraw TE, Greenfield L, Maxfield FR. Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor. The Journal of Cell Biology. 105: 207-14. PMID 3611186  1
1987 Palombella VJ, Yamashiro DJ, Maxfield FR, Decker SJ, Vilcek J. Tumor necrosis factor increases the number of epidermal growth factor receptors on human fibroblasts. The Journal of Biological Chemistry. 262: 1950-4. PMID 3546282  1
1987 Maxfield FR, Yamashiro DJ. Endosome acidification and the pathways of receptor-mediated endocytosis. Advances in Experimental Medicine and Biology. 225: 189-98. PMID 2839960  1
1987 Yamashiro DJ, Maxfield FR. Acidification of morphologically distinct endosomes in mutant and wild-type Chinese hamster ovary cells. The Journal of Cell Biology. 105: 2723-33. PMID 2447098  1
1987 Yamashiro DJ, Maxfield FR. Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells. The Journal of Cell Biology. 105: 2713-21. PMID 2447097  1
1986 Ratan RR, Shelanski ML, Maxfield FR. Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 5136-40. PMID 3460085  1
1986 Kruskal BA, Shak S, Maxfield FR. Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium. Proceedings of the National Academy of Sciences of the United States of America. 83: 2919-23. PMID 3458251  1
1985 Keith CH, Ratan R, Maxfield FR, Bajer A, Shelanski ML. Local cytoplasmic calcium gradients in living mitotic cells. Nature. 316: 848-50. PMID 4033782 DOI: 10.1038/316848a0  1
1985 Keith CH, Maxfield FR, Shelanski ML. Intracellular free calcium levels are reduced in mitotic Pt K2 epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 800-4. PMID 3856233  1
1985 Maxfield FR. Calcium and pH in cytoplasmic organelles Trends in Biochemical Sciences. 10: 443-447. DOI: 10.1016/0968-0004(85)90028-3  1
1984 Horwitz MA, Maxfield FR. Legionella pneumophila inhibits acidification of its phagosome in human monocytes. The Journal of Cell Biology. 99: 1936-43. PMID 6501409  1
1984 Kruskal BA, Keith CH, Maxfield FR. Thyrotropin-releasing hormone-induced changes in intracellular [Ca2+] measured by microspectrofluorometry on individual quin2-loaded cells. The Journal of Cell Biology. 99: 1167-72. PMID 6432803  1
1984 DiPaola M, Keith CH, Feldman D, Tycko B, Maxfield FR. Loss of alpha 2-macroglobulin and epidermal growth factor surface binding induced by phenothiazines and naphthalene sulfonamides. Journal of Cellular Physiology. 118: 193-202. PMID 6319437 DOI: 10.1002/jcp.1041180212  1
1984 Yamashiro DJ, Tycko B, Fluss SR, Maxfield FR. Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell. 37: 789-800. PMID 6204769 DOI: 10.1016/0092-8674(84)90414-8  1
1984 DiPaola M, Maxfield FR. Conformational changes in the receptors for epidermal growth factor and asialoglycoproteins induced by the mildly acidic pH found in endocytic vesicles. The Journal of Biological Chemistry. 259: 9163-71. PMID 6086623  1
1984 Yamashiro DJ, Maxfield FR. Acidification of endocytic compartments and the intracellular pathways of ligands and receptors. Journal of Cellular Biochemistry. 26: 231-46. PMID 6085081 DOI: 10.1002/jcb.240260404  1
1983 Keith C, DiPaola M, Maxfield FR, Shelanski ML. Microinjection of Ca++-calmodulin causes a localized depolymerization of microtubules. The Journal of Cell Biology. 97: 1918-24. PMID 6358237  1
1983 Tycko B, Keith CH, Maxfield FR. Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line. The Journal of Cell Biology. 97: 1762-76. PMID 6315742  1
1983 Yamashiro DJ, Fluss SR, Maxfield FR. Acidification of endocytic vesicles by an ATP-dependent proton pump. The Journal of Cell Biology. 97: 929-34. PMID 6224803  1
1983 Tycko B, DiPaola M, Yamashiro DJ, Fluss S, Maxfield FR. Acidification of endocytic vesicles and the intracellular pathways of ligands and receptors. Annals of the New York Academy of Sciences. 421: 424-33. PMID 6202216  1
1982 Maxfield FR. Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. The Journal of Cell Biology. 95: 676-81. PMID 6183281  1
1982 Keen JH, Maxfield FR, Hardegree MC, Habig WH. Receptor-mediated endocytosis of diphtheria toxin by cells in culture. Proceedings of the National Academy of Sciences of the United States of America. 79: 2912-6. PMID 6178112  1
1982 Tycko B, Maxfield FR. Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell. 28: 643-51. PMID 6176331 DOI: 10.1016/0092-8674(82)90219-7  1
1981 Han SL, Stimson ER, Maxfield FR, Scheraga HA. Spectroscopic study of the conformations of proline-containing oligopeptides in the crystalline state and in solution. International Journal of Peptide and Protein Research. 17: 297-315. PMID 7287301  0.96
1981 Maxfield FR, Willingham MC, Pastan I, Dragsten P, Cheng SY. Binding and mobility of the cell surface receptors for 3,3',5-triiodo-L-thyronine. Science (New York, N.Y.). 211: 63-5. PMID 6255563  1
1981 Maxfield FR, Willingham MC, Haigler HT, Dragsten P, Pastan IH. Binding, surface mobility, internalization, and degradation of rhodamine-labeled alpha 2-macroglobulin. Biochemistry. 20: 5353-8. PMID 6170323  1
1981 Maxfield FR, Bandekar J, Krimm S, Evans DJ, Leach SJ, Nemethy G, Scheraga HA. Conformation of cyclo(L-alanylglycyl-ε-aminocaproyl), a cyclized dipeptide model for a β bend. 3. Infrared and Raman spectroscopic studies Macromolecules. 14: 997-1003.  1
1980 Han SL, Stimson ER, Maxfield FR, Leach SJ, Scheraga HA. Study of the state of ionization of [Leu5]-enkephalin in the crystal and in solution. International Journal of Peptide and Protein Research. 16: 183-90. PMID 7461900  0.96
1980 Han SL, Stimson ER, Maxfield FR, Scheraga HA. Conformational study of [Leu5]-enkephalin by laser Raman spectroscopy. International Journal of Peptide and Protein Research. 16: 173-81. PMID 7461899  0.96
1980 Haigler HT, Maxfield FR, Willingham MC, Pastan I. Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells. The Journal of Biological Chemistry. 255: 1239-41. PMID 6243633  1
1980 Willingham MC, Maxfield FR, Pastan I. Receptor-mediated endocytosis of alpha 2-macroglobulin in cultured fibroblasts. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 28: 818-23. PMID 6160180  0.64
1980 Cheng SY, Maxfield FR, Robbins J, Willingham MC, Pastan IH. Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 77: 3425-9. PMID 6158047  0.64
1980 Davies PJ, Davies DR, Levitzki A, Maxfield FR, Milhaud P, Willingham MC, Pastan IH. Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones. Nature. 283: 162-7. PMID 6153122  0.64
1979 Deslauriers R, Leach SJ, Maxfield FR, Minasian E, McQuie JR, Meinwald YC, Némethy G, Pottle MS, Rae ID, Scheraga HA, Stimson ER, Van Nispen JW. Cyclized dipeptide model for a beta-bend. Proceedings of the National Academy of Sciences of the United States of America. 76: 2512-4. PMID 288041 DOI: 10.1073/pnas.76.6.2512  1
1979 Maxfield FR, Scheraga HA. Improvements in the prediction of protein backbone topography by reduction of statistical errors. Biochemistry. 18: 697-704. PMID 217422  0.96
1979 Willingham MC, Maxfield FR, Pastan IH. alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions. The Journal of Cell Biology. 82: 614-25. PMID 92473  0.64
1979 Maxfield FR, Willingham MC, Davies PJ, Pastan I. Amines inhibit the clustering of alpha2-macroglobulin and EGF on the fibroblast cell surface. Nature. 277: 661-3. PMID 85262  0.64
1979 Maxfield FR, Davies PJ, Klempner L, Willingham MC, Pastan I. Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits. Proceedings of the National Academy of Sciences of the United States of America. 76: 5731-5. PMID 42903  0.64
1978 Maxfield FR, Schlessinger J, Shechter Y, Pastan I, Willingham MC. Collection of insulin, EGF and alpha2-macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization. Cell. 14: 805-10. PMID 80283 DOI: 10.1016/0092-8674(78)90336-7  1
1977 Maxfield FR, Scheraga HA. A Raman spectroscopic investigation of the disulfide conformation in oxytocin and lysine vasopressin. Biochemistry. 16: 4443-9. PMID 911768  0.96
1976 Maxfield FR, Scheraga HA. Status of empirical methods for the prediction of protein backbone topography. Biochemistry. 15: 5138-53. PMID 990270  0.96
1975 Maxfield FR, Scheraga HA. The effect of neighboring charges on the helix forming ability of charged amino acids in proteins. Macromolecules. 8: 491-3. PMID 1177494  0.96
1975 Maxfield FR, Alter JE, Taylor GT, Scheraga HA. Helix-coil stability constants for the naturally occurring amino acids in water. IX. Glutamic acid parameters from random poly(hydroxybutylglutamine-co-L-glutamic acid). Macromolecules. 8: 479-91. PMID 240987  0.96
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