Othman Ghribi - Publications

Affiliations: 
The University of North Dakota, Grand Forks, ND, United States 
Area:
Pharmacology, Physiology Biology, Biochemistry, Molecular Biology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Marwarha G, Claycombe-Larson K, Lund J, Schommer J, Ghribi O. A Diet Enriched in Palmitate and Deficient in Linoleate Exacerbates Oxidative Stress and Amyloid-β Burden in the Hippocampus of 3xTg-AD Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30714957 DOI: 10.3233/Jad-180835  0.783
2018 Marwarha G, Claycombe-Larson K, Lund J, Ghribi O. Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis. Molecular Neurobiology. PMID 30569418 DOI: 10.1007/S12035-018-1451-8  0.78
2018 Schommer J, Marwarha G, Nagamoto-Combs K, Ghribi O. Palmitic Acid-Enriched Diet Increases α-Synuclein and Tyrosine Hydroxylase Expression Levels in the Mouse Brain. Frontiers in Neuroscience. 12: 552. PMID 30127714 DOI: 10.3389/Fnins.2018.00552  0.709
2018 Warns J, Marwarha G, Freking N, Ghribi O. 27-hydroxycholesterol decreases cell proliferation in colon cancer cell lines. Biochimie. PMID 30009860 DOI: 10.1016/J.Biochi.2018.07.006  0.701
2018 Schommer J, Marwarha G, Schommer T, Flick T, Lund J, Ghribi O. 27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons. Bmc Neuroscience. 19: 17. PMID 29614969 DOI: 10.1186/S12868-018-0420-5  0.708
2018 Marwarha G, Schommer J, Lund J, Schommer T, Ghribi O. Palmitate induced C/EBP homologous protein activation leads to NF-κB -mediated increase in BACE1 activity and Amyloid beta genesis. Journal of Neurochemistry. PMID 29315574 DOI: 10.1111/Jnc.14292  0.779
2018 Marwarha G, Lund J, Ghribi O. P2-146: SIGNALING CROSSTALK BETWEEN NF-KAPPA B AND GADD153 UNDERLIES THE SATURATED FAT-ENRICHED DIET INDUCED INCREASE IN AMYLOID β BURDEN IN THE MOUSE HIPPOCAMPUS Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.832  0.732
2018 Marwarha G, Ghribi O. P4-056: Androgen Receptor Activation Regulates Bace1 Expression And Amyloid Beta Genesis In Cultured Human Neuroblastoma Cells Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2459  0.715
2018 Marwarha G, Ghribi O. P1-184: Estradiol Reduces Basal Bace1 Expression Through The Activation Of Estrogen Receptor Alpha Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.188  0.681
2018 Marwarha G, Lund J, Ghribi O. P3-141: Calcitriol Attenuates Amyloid-Beta Genesis In Cultured Human Sh-Sy5Y Neuroblastoma And Rat Pheochromocytoma Pc12 Cells Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1498  0.694
2017 Gongol B, Marin TL, Jeppson JD, Mayagoitia K, Shin S, Sanchez N, Kirsch WM, Vinters HV, Wilson CG, Ghribi O, Soriano S. Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity. Scientific Reports. 7: 13898. PMID 29066835 DOI: 10.1038/S41598-017-13933-9  0.47
2017 Ghribi O. NF-κB - a friend, a foe, or a bystander - in the neurodegenerative cascade and pathogenesis of Alzheimer's disease. Cns & Neurological Disorders Drug Targets. PMID 28745240 DOI: 10.2174/1871527316666170725114652  0.406
2017 Marwarha G, Raza S, Hammer K, Ghribi O. 27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer. Chemistry and Physics of Lipids. PMID 28583434 DOI: 10.1016/J.Chemphyslip.2017.05.012  0.661
2017 Raza S, Meyer M, Goodyear C, Hammer KDP, Guo B, Ghribi O. The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells. Cancer Cell International. 17: 52. PMID 28503095 DOI: 10.1186/S12935-017-0422-X  0.319
2017 Schommer J, Schrag M, Nackenoff A, Marwarha G, Ghribi O. Method for organotypic tissue culture in the aged animal. Methodsx. 4: 166-171. PMID 28462173 DOI: 10.1016/J.Mex.2017.03.003  0.681
2017 Marwarha G, Claycombe-Larson K, Schommer J, Ghribi O. Maternal low-protein diet decreases brain-derived neurotrophic factor expression in the brains of the neonatal rat offspring. The Journal of Nutritional Biochemistry. 45: 54-66. PMID 28432877 DOI: 10.1016/J.Jnutbio.2017.03.005  0.695
2017 Marwarha G, Rostad S, Lilek J, Kleinjan M, Schommer J, Ghribi O. Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation. Journal of Alzheimer's Disease : Jad. PMID 28304295 DOI: 10.3233/Jad-161130  0.782
2017 Ghribi O, Marwarha G. Palmitate Induces Bace1 Expression And Activity By Inducing Sterol Response Element Binding Protein 1 Expression And Activation In The Mouse Hippocampus And Human Sh-Sy5Y Neuroblastoma Cells Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.779  0.705
2017 Marwarha G, Ghribi O. Palmitate-Enriched Diet-Induced Er Stress And Chop Activation Causes Tau Hyperphosphorylation In The Cultured Human Neuroblastoma Cells And The Mouse Brain Alzheimers & Dementia. 13: 326. DOI: 10.1016/J.Jalz.2017.06.036  0.73
2016 Vomhof-DeKrey E, Darland D, Ghribi O, Bundy A, Roemmich J, Claycombe K. Maternal low protein diet leads to placental angiogenic compensation via dysregulated M1/M2 macrophages and TNFα expression in Sprague-Dawley rats. Journal of Reproductive Immunology. 118: 9-17. PMID 27596280 DOI: 10.1016/J.Jri.2016.08.009  0.308
2016 Marwarha G, Claycomb K, Schommer J, Collins D, Ghribi O. Palmitate-induced endoplasmic reticulum stress and subsequent C/EBPα homologous protein activation attenuates leptin and insulin-like growth factor 1 expression in the brain. Cellular Signalling. PMID 27555288 DOI: 10.1016/J.Cellsig.2016.08.012  0.734
2016 Chen X, Wagener JF, Ghribi O, Geiger JD. Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease. Frontiers in Aging Neuroscience. 8: 129. PMID 27375475 DOI: 10.3389/Fnagi.2016.00129  0.436
2016 Liu QY, Koukiekolo R, Zhang DL, Smith B, Ly D, Lei JX, Ghribi O. Molecular events linking cholesterol to Alzheimer's disease and inclusion body myositis in a rabbit model. American Journal of Neurodegenerative Disease. 5: 74-84. PMID 27073745  0.302
2016 Raza S, Meyer M, Schommer J, Hammer KD, Guo B, Ghribi O. 27-Hydroxycholesterol stimulates cell proliferation and resistance to docetaxel-induced apoptosis in prostate epithelial cells. Medical Oncology (Northwood, London, England). 33: 12. PMID 26732475 DOI: 10.1007/S12032-015-0725-5  0.325
2015 Raza S, Ohm JE, Dhasarathy A, Schommer J, Roche C, Hammer KD, Ghribi O. The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells. Molecular and Cellular Biochemistry. 410: 187-95. PMID 26350565 DOI: 10.1007/S11010-015-2551-7  0.333
2015 Marwarha G, Ghribi O. Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap? Experimental Gerontology. 68: 13-8. PMID 25261765 DOI: 10.1016/J.Exger.2014.09.013  0.736
2015 Raza S, Meyer M, Guo B, Hammer K, Ghribi O. Abstract B20: The cholesterol metabolite, 27-hydroxycholesterol induces hyperplasia in an androgen receptor-dependent manner in normal prostate RWPE-1 cells Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-B20  0.333
2015 Raza S, Schommer J, Meyer M, Guo B, Hammer K, Ghribi O. Abstract 5048: The cholesterol metabolite, 27-hydroxycholesterol stimulates cell proliferation in prostate epithelial cell lines via estrogen receptor beta Cancer Research. 75: 5048-5048. DOI: 10.1158/1538-7445.Am2015-5048  0.356
2014 Morgan DH, Ghribi O, Hui L, Geiger JD, Chen X. Cholesterol-enriched diet disrupts the blood-testis barrier in rabbits. American Journal of Physiology. Endocrinology and Metabolism. 307: E1125-30. PMID 25336525 DOI: 10.1152/Ajpendo.00416.2014  0.349
2014 Marwarha G, Raza S, Meiers C, Ghribi O. Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway. Biochimica Et Biophysica Acta. 1842: 1587-95. PMID 24874077 DOI: 10.1016/J.Jalz.2014.05.311  0.768
2013 Marwarha G, Raza S, Prasanthi JR, Ghribi O. Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells. Plos One. 8: e70773. PMID 23951005 DOI: 10.1371/Journal.Pone.0070773  0.766
2013 Schrag M, Mueller C, Zabel M, Crofton A, Kirsch WM, Ghribi O, Squitti R, Perry G. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis. Neurobiology of Disease. 59: 100-10. PMID 23867235 DOI: 10.1016/J.Nbd.2013.07.005  0.354
2013 Dasari B, Prasanthi JR, Meiers C, Singh BB, Ghribi O. Differential effects of the estrogen receptor agonist estradiol on toxicity induced by enzymatically-derived or autoxidation-derived oxysterols in human ARPE-19 cells. Current Eye Research. 38: 1159-71. PMID 23841471 DOI: 10.3109/02713683.2013.811257  0.779
2012 Liu QY, Bingham EJ, Twine SM, Geiger JD, Ghribi O. Metabolomic Identification in Cerebrospinal Fluid of the Effects of High Dietary Cholesterol in a Rabbit Model of Alzheimer's Disease. Metabolomics : Open Access. 2: 109. PMID 24851192  0.306
2012 Patel MY, Panchal HV, Ghribi O, Benzeroual KE. The neuroprotective effect of fisetin in the MPTP model of Parkinson's disease. Journal of Parkinson's Disease. 2: 287-302. PMID 23938259 DOI: 10.3233/Jpd-012110  0.335
2012 Marwarha G, Ghribi O. Leptin signaling and Alzheimer's disease. American Journal of Neurodegenerative Disease. 1: 245-65. PMID 23383396  0.732
2012 Prasanthi JR, Schrag M, Dasari B, Marwarha G, Dickson A, Kirsch WM, Ghribi O. Deferiprone reduces amyloid-β and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched diet. Journal of Alzheimer's Disease : Jad. 30: 167-82. PMID 22406440 DOI: 10.3233/Jad-2012-111346  0.8
2012 Liu R, Lei JX, Luo C, Lan X, Chi L, Deng P, Lei S, Ghribi O, Liu QY. Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease. Neurobiology of Disease. 45: 902-12. PMID 22186421 DOI: 10.1016/J.Nbd.2011.12.007  0.405
2012 Marwarha G, Ghribi O. Cellular model of Alzheimer's disease--relevance to therapeutic testing. Experimental Neurology. 233: 733-9. PMID 22119424 DOI: 10.1016/J.Expneurol.2011.11.011  0.705
2012 Marwarha G, Dasari B, Ghribi O. Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol. Cellular Signalling. 24: 484-92. PMID 21983012 DOI: 10.1016/J.Cellsig.2011.09.029  0.808
2012 Ghribi O. The saturated fatty acid palmitate increases beta-amyloid through gadd153-induced BACE1 overexpression Alzheimers & Dementia. 8: 646. DOI: 10.1016/J.Jalz.2012.05.1730  0.339
2011 Prasanthi JR, Larson T, Schommer J, Ghribi O. Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus. Plos One. 6: e26420. PMID 22046282 DOI: 10.1371/Journal.Pone.0026420  0.56
2011 Marwarha G, Rhen T, Schommer T, Ghribi O. The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors--relevance to Parkinson's disease. Journal of Neurochemistry. 119: 1119-36. PMID 21951066 DOI: 10.1111/J.1471-4159.2011.07497.X  0.711
2011 Dasari B, Prasanthi JR, Marwarha G, Singh BB, Ghribi O. Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina. Bmc Ophthalmology. 11: 22. PMID 21851605 DOI: 10.1186/1471-2415-11-22  0.806
2011 Marwarha G, Prasanthi JR, Schommer J, Dasari B, Ghribi O. Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus. Molecular Neurodegeneration. 6: 41. PMID 21651786 DOI: 10.1186/1750-1326-6-41  0.794
2010 Chen X, Wagener JF, Morgan DH, Hui L, Ghribi O, Geiger JD. Endolysosome mechanisms associated with Alzheimer's disease-like pathology in rabbits ingesting cholesterol-enriched diet. Journal of Alzheimer's Disease : Jad. 22: 1289-303. PMID 20930277 DOI: 10.3233/Jad-2010-101323  0.511
2010 Dasari B, Prasanthi JR, Marwarha G, Singh BB, Ghribi O. The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells. Bmc Ophthalmology. 10: 22. PMID 20836858 DOI: 10.1186/1471-2415-10-22  0.8
2010 Marwarha G, Dasari B, Prabhakara JP, Schommer J, Ghribi O. β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway. Journal of Neurochemistry. 115: 373-84. PMID 20670375 DOI: 10.1111/J.1471-4159.2010.06929.X  0.797
2010 Prasanthi JR, Dasari B, Marwarha G, Larson T, Chen X, Geiger JD, Ghribi O. Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet. Free Radical Biology & Medicine. 49: 1212-20. PMID 20638472 DOI: 10.1016/J.Freeradbiomed.2010.07.007  0.81
2010 Chen X, Ghribi O, Geiger JD. Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases. Journal of Alzheimer's Disease : Jad. 20: S127-41. PMID 20164568 DOI: 10.3233/Jad-2010-1376  0.374
2010 Marwarha G, Dasari B, Prasanthi JR, Schommer J, Ghribi O. Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices. Journal of Alzheimer's Disease : Jad. 19: 1007-19. PMID 20157255 DOI: 10.3233/Jad-2010-1298  0.814
2010 Ghribi O, Marwarha G. Cholesterol causes Alzheimer pathology through Akt/mTOR inhibition Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1355  0.743
2009 Wu M, Audet A, Cusic J, Seeger D, Cochran R, Ghribi O. Broad DNA repair responses in neural injury are associated with activation of the IL-6 pathway in cholesterol-fed rabbits. Journal of Neurochemistry. 111: 1011-21. PMID 19765189 DOI: 10.1111/J.1471-4159.2009.06390.X  0.383
2009 Prasanthi JR, Huls A, Thomasson S, Thompson A, Schommer E, Ghribi O. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. Molecular Neurodegeneration. 4: 1. PMID 19126211 DOI: 10.1186/1750-1326-4-1  0.468
2009 Ghribi O, Schommer E, Prasanthi JRP. 27-hydroxycholestrol as the missing link between circulating cholesterol and AD-like pathology Alzheimers & Dementia. 5: 180. DOI: 10.1016/J.Jalz.2009.04.031  0.447
2008 Ghribi O. Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscle. Journal of Alzheimer's Disease : Jad. 15: 673-84. PMID 19096164 DOI: 10.3233/Jad-2008-15412  0.502
2008 Rantham Prabhakara JP, Feist G, Thomasson S, Thompson A, Schommer E, Ghribi O. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells. Journal of Neurochemistry. 107: 1722-9. PMID 19014385 DOI: 10.1111/J.1471-4159.2008.05736.X  0.36
2008 Jaya Prasanthi RP, Schommer E, Thomasson S, Thompson A, Feist G, Ghribi O. Regulation of beta-amyloid levels in the brain of cholesterol-fed rabbit, a model system for sporadic Alzheimer's disease. Mechanisms of Ageing and Development. 129: 649-55. PMID 18845178 DOI: 10.1016/J.Mad.2008.09.002  0.469
2008 Sharma S, Prasanthi R P J, Schommer E, Feist G, Ghribi O. Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling. Neurobiology of Disease. 32: 426-32. PMID 18775495 DOI: 10.1016/J.Nbd.2008.08.002  0.45
2008 Chen X, Gawryluk JW, Wagener JF, Ghribi O, Geiger JD. Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease. Journal of Neuroinflammation. 5: 12. PMID 18387175 DOI: 10.1186/1742-2094-5-12  0.442
2008 Chen X, Ghribi O, Geiger JD. Rabbits fed cholesterol-enriched diets exhibit pathological features of inclusion body myositis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R829-35. PMID 18216139 DOI: 10.1152/Ajpregu.00639.2007  0.45
2008 Schrag M, Sharma S, Brown-Borg H, Ghribi O. Hippocampus of Ames dwarf mice is resistant to beta-amyloid-induced tau hyperphosphorylation and changes in apoptosis-regulatory protein levels. Hippocampus. 18: 239-44. PMID 18000817 DOI: 10.1002/Hipo.20387  0.446
2008 Ghribi O, Feist G, Prasanthi J. P4-247: Oxysterols induce Alzheimer's disease-like pathological hallmarks Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.2315  0.404
2007 Savory J, Ghribi O. Can studies of aluminum toxicity in vivo and in vitro provide relevant information on the pathogenesis and etiology of Alzheimer's disease? Journal of Alzheimer's Disease : Jad. 11: 429-30; discussion 4. PMID 17656820 DOI: 10.3233/Jad-2007-11402  0.347
2006 Ghribi O. Preservation of the blood brain barrier integrity may underlie neuroprotective effects of statins in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 10: 407-8. PMID 17183152 DOI: 10.3233/Jad-2006-10409  0.371
2006 Savory J, Herman MM, Ghribi O. Mechanisms of aluminum-induced neurodegeneration in animals: Implications for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 10: 135-44. PMID 17119283 DOI: 10.3233/Jad-2006-102-302  0.402
2006 Ghribi O, Golovko MY, Larsen B, Schrag M, Murphy EJ. Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets. Journal of Neurochemistry. 99: 438-49. PMID 17029598 DOI: 10.1111/J.1471-4159.2006.04079.X  0.42
2006 Savory J, Herman MM, Ghribi O. Supplementation of the diet with silicic acid to reduce body burden of aluminum: a miracle cure or useless treatment for Alzheimer's disease? Journal of Alzheimer's Disease : Jad. 10: 25-7. PMID 16988477 DOI: 10.3233/Jad-2006-10104  0.316
2006 Dewitt DA, Hurd JA, Fox N, Townsend BE, Griffioen KJ, Ghribi O, Savory J. Peri-nuclear clustering of mitochondria is triggered during aluminum maltolate induced apoptosis. Journal of Alzheimer's Disease : Jad. 9: 195-205. PMID 16873966 DOI: 10.3233/Jad-2006-9211  0.323
2006 Ghribi O, Larsen B, Schrag M, Herman MM. High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus. Experimental Neurology. 200: 460-7. PMID 16696972 DOI: 10.1016/J.Expneurol.2006.03.019  0.463
2006 Ghribi O. The role of the endoplasmic reticulum in the accumulation of beta-amyloid peptide in Alzheimer's disease. Current Molecular Medicine. 6: 119-33. PMID 16472119 DOI: 10.2174/156652406775574514  0.461
2004 Ghribi O, Herman MM, Pramoonjago P, Spaulding NK, Savory J. GDNF regulates the A beta-induced endoplasmic reticulum stress response in rabbit hippocampus by inhibiting the activation of gadd 153 and the JNK and ERK kinases. Neurobiology of Disease. 16: 417-27. PMID 15193298 DOI: 10.1016/J.Nbd.2004.04.002  0.459
2004 Ghribi O, Herman MM, Savory J. P1-357 Aβ-induced P-tau and apoptosis in rabbit brain are two independent events Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80669-9  0.356
2003 Ghribi O, Herman MM, Pramoonjago P, Savory J. MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-kappaB signaling pathways. Journal of Neuropathology and Experimental Neurology. 62: 1144-53. PMID 14656072 DOI: 10.1093/Jnen/62.11.1144  0.386
2003 Ghribi O, Prammonjago P, Herman MM, Spaulding NK, Savory J. Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau. Brain Research. Molecular Brain Research. 119: 201-6. PMID 14625087 DOI: 10.1016/J.Molbrainres.2003.09.001  0.419
2003 Savory J, Herman MM, Ghribi O. Intracellular mechanisms underlying aluminum-induced apoptosis in rabbit brain. Journal of Inorganic Biochemistry. 97: 151-4. PMID 14507471 DOI: 10.1016/S0162-0134(03)00258-7  0.322
2003 Ghribi O, Herman MM, Savory J. Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation. Journal of Neuroscience Research. 71: 853-62. PMID 12605412 DOI: 10.1002/Jnr.10511  0.388
2002 Ghribi O, Herman MM, Spaulding NK, Savory J. Lithium inhibits aluminum-induced apoptosis in rabbit hippocampus, by preventing cytochrome c translocation, Bcl-2 decrease, Bax elevation and caspase-3 activation. Journal of Neurochemistry. 82: 137-45. PMID 12091474 DOI: 10.1046/J.1471-4159.2002.00957.X  0.322
2002 Ghribi O, Herman MM, Savory J. The endoplasmic reticulum is the main site for caspase-3 activation following aluminum-induced neurotoxicity in rabbit hippocampus. Neuroscience Letters. 324: 217-21. PMID 12009527 DOI: 10.1016/S0304-3940(02)00147-7  0.302
2001 Ghribi O, DeWitt DA, Forbes MS, Arad A, Herman MM, Savory J. Cyclosporin A inhibits Al-induced cytochrome c release from mitochondria in aged rabbits. Journal of Alzheimer's Disease : Jad. 3: 387-391. PMID 12214041 DOI: 10.3233/Jad-2001-3404  0.317
2001 Ghribi O, Herman MM, DeWitt DA, Forbes MS, Savory J. Abeta(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-kappaB. Brain Research. Molecular Brain Research. 96: 30-8. PMID 11731006 DOI: 10.1016/S0169-328X(01)00256-X  0.392
2001 Ghribi O, Herman MM, Forbes MS, DeWitt DA, Savory J. GDNF protects against aluminum-induced apoptosis in rabbits by upregulating Bcl-2 and Bcl-XL and inhibiting mitochondrial Bax translocation. Neurobiology of Disease. 8: 764-73. PMID 11592846 DOI: 10.1006/Nbdi.2001.0429  0.346
2001 Ghribi O, DeWitt DA, Forbes MS, Herman MM, Savory J. Co-involvement of mitochondria and endoplasmic reticulum in regulation of apoptosis: changes in cytochrome c, Bcl-2 and Bax in the hippocampus of aluminum-treated rabbits. Brain Research. 903: 66-73. PMID 11382389 DOI: 10.1016/S0006-8993(01)02406-4  0.356
2001 Valastro B, Ghribi O, Poirier J, Krzywkowski P, Massicotte G. AMPA receptor regulation and LTP in the hippocampus of young and aged apolipoprotein E-deficient mice. Neurobiology of Aging. 22: 9-15. PMID 11164271 DOI: 10.1016/S0197-4580(00)00177-9  0.314
1999 Krzywkowski P, Ghribi O, Gagné J, Chabot C, Kar S, Rochford J, Massicotte G, Poirier J. Cholinergic systems and long-term potentiation in memory-impaired apolipoprotein E-deficient mice. Neuroscience. 92: 1273-86. PMID 10426483 DOI: 10.1016/S0306-4522(99)00061-5  0.332
1999 Ghribi O, Lapierre L, Girard M, Ohayon M, Nalbantoglu J, Massicotte G. Hypoxia-induced loss of synaptic transmission is exacerbated in hippocampal slices of transgenic mice expressing C-terminal fragments of Alzheimer amyloid precursor protein. Hippocampus. 9: 201-5. PMID 10401636 DOI: 10.1002/(Sici)1098-1063(1999)9:3<201::Aid-Hipo1>3.0.Co;2-P  0.334
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