| Year |
Citation |
Score |
| 2023 |
Adhikary U, Paulo JA, Godes M, Roychoudhury S, Prew MS, Ben-Nun Y, Yu EW, Budhraja A, Opferman JT, Chowdhury D, Gygi SP, Walensky LD. Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction. Cell Reports. 42: 113176. PMID 37773750 DOI: 10.1016/j.celrep.2023.113176 |
0.347 |
|
| 2023 |
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Opferman JT, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w |
0.352 |
|
| 2022 |
Prew MS, Adhikary U, Choi DW, Portero EP, Paulo JA, Gowda P, Budhraja A, Opferman JT, Gygi SP, Danial NN, Walensky LD. MCL-1 is a master regulator of cancer dependency on fatty acid oxidation. Cell Reports. 41: 111445. PMID 36198266 DOI: 10.1016/j.celrep.2022.111445 |
0.381 |
|
| 2021 |
Flemmer RT, Connolly SP, Geizer BA, Opferman JT, Vanderluit JL. The Role of Mcl-1 in Embryonic Neural Precursor Cell Apoptosis. Frontiers in Cell and Developmental Biology. 9: 659531. PMID 33959612 DOI: 10.3389/fcell.2021.659531 |
0.33 |
|
| 2021 |
Turnis ME, Kaminska E, Smith KH, Kartchner BJ, Vogel P, Laxton JD, Ashmun RA, Ney PA, Opferman JT. Requirement for Anti-Apoptotic MCL-1 during Early Erythropoiesis. Blood. PMID 33512417 DOI: 10.1182/blood.2020006916 |
0.347 |
|
| 2020 |
Smith KH, Budhraja A, Lynch J, Roberts K, Panetta JC, Connelly JP, Turnis ME, Pruett-Miller SM, Schuetz JD, Mullighan CG, Opferman JT. The Heme-regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics. Molecular Cancer Research : McR. PMID 33288732 DOI: 10.1158/1541-7786.MCR-20-0586 |
0.404 |
|
| 2019 |
Villalobos-Ortiz M, Ryan J, Mashaka TN, Opferman JT, Letai A. BH3 profiling discriminates on-target small molecule BH3 mimetics from putative mimetics. Cell Death and Differentiation. PMID 31332296 DOI: 10.1038/S41418-019-0391-9 |
0.487 |
|
| 2019 |
Ling T, Lang WH, Craig J, Potts MB, Budhraja A, Opferman J, Bollinger J, Maier J, Marsico TD, Rivas F. Studies of Jatrogossone A as a Reactive Oxygen Species Inducer in Cancer Cellular Models. Journal of Natural Products. PMID 31084028 DOI: 10.1021/Acs.Jnatprod.8B01087 |
0.445 |
|
| 2019 |
Lee T, Christov PP, Shaw S, Tarr JC, Zhao B, Veerasamy N, Jeon KO, Mills JJ, Bian Z, Sensintaffar JL, Arnold AL, Fogarty SA, Perry E, Ramsey HE, Cook R, ... ... Opferman JT, et al. Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors that Demonstrate in vivo Activity in Mouse Xenograft Models of Human Cancer. Journal of Medicinal Chemistry. PMID 30929420 DOI: 10.2210/Pdb6Ne5/Pdb |
0.42 |
|
| 2018 |
Opferman JT, Kothari A. Anti-apoptotic BCL-2 family members in development. Cell Death and Differentiation. 25: 37-45. PMID 31745314 DOI: 10.1038/cdd.2017.170 |
0.347 |
|
| 2018 |
Ling T, Maier J, Das S, Budhraja A, Bassett R, Potts MB, Shelat A, Rankovic Z, Opferman JT, Rivas F. Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents. European Journal of Medicinal Chemistry. 164: 391-398. PMID 30611980 DOI: 10.1016/J.Ejmech.2018.12.059 |
0.405 |
|
| 2018 |
Vallet S, Fan F, Malvestiti S, Pecherstorfer M, Sattler M, Schneeweiss A, Schulze-Bergkamen H, Opferman JT, Cardone MH, Jäger D, Podar K. Rationally derived drug combinations with the novel Mcl-1 inhibitor EU-5346 in breast cancer. Breast Cancer Research and Treatment. PMID 30374681 DOI: 10.1007/S10549-018-5022-5 |
0.355 |
|
| 2018 |
Fogarty LC, Flemmer RT, Geizer BA, Licursi M, Karunanithy A, Opferman JT, Hirasawa K, Vanderluit JL. Mcl-1 and Bcl-xL are essential for survival of the developing nervous system. Cell Death and Differentiation. PMID 30361616 DOI: 10.1038/S41418-018-0225-1 |
0.492 |
|
| 2018 |
Cunha LD, Yang M, Carter R, Guy C, Harris L, Crawford JC, Quarato G, Boada-Romero E, Kalkavan H, Johnson MDL, Natarajan S, Turnis ME, Finkelstein D, Opferman JT, Gawad C, et al. LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance. Cell. PMID 30245008 DOI: 10.1016/J.Cell.2018.08.061 |
0.368 |
|
| 2018 |
Escudero S, Zaganjor E, Lee S, Mill CP, Morgan AM, Crawford EB, Chen J, Wales TE, Mourtada R, Luccarelli J, Bird GH, Steidl U, Engen JR, Haigis MC, Opferman JT, et al. Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD. Molecular Cell. 69: 729-743.e7. PMID 29499131 DOI: 10.1016/J.Molcel.2018.02.005 |
0.382 |
|
| 2018 |
Chen B, Pamela W, Auclair D, Keats JJ, Secrist P, Cidado J, Tron AE, Dunham CM, Lonial S, Opferman J, Matulis SM, Boise LH. Myeloma Patient-Derived MCL1 Point Mutations Can Influence MCL1-Inhibitor Function Blood. 132: 951-951. DOI: 10.1182/Blood-2018-99-113444 |
0.375 |
|
| 2017 |
Opferman JT, Kothari A. Anti-apoptotic BCL-2 family members in development. Cell Death and Differentiation. PMID 29099482 DOI: 10.1038/Cdd.2017.170 |
0.46 |
|
| 2017 |
Budhraja A, Turnis ME, Churchman ML, Kothari A, Yang X, Xu H, Kaminska E, Panetta JC, Finkelstein D, Mullighan CG, Opferman JT. Modulation of Navitoclax Sensitivity by Dihydroartemisinin-Mediated MCL-1 Repression in BCR-ABL+ B-Lineage Acute Lymphoblastic Leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28974549 DOI: 10.1158/1078-0432.Ccr-17-1231 |
0.473 |
|
| 2017 |
Wu X, Zhang LS, Toombs J, Kuo YC, Piazza JT, Tuladhar R, Barrett Q, Fan CW, Zhang X, Walensky LD, Kool M, Cheng SY, Brekken R, Opferman JT, Green DR, et al. Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor. Nature Cell Biology. PMID 28945232 DOI: 10.1038/Ncb3616 |
0.488 |
|
| 2017 |
van Oosterwijk JG, Li C, Yang X, Opferman JT, Sherr CJ. Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28652370 DOI: 10.1073/Pnas.1707292114 |
0.389 |
|
| 2016 |
Lee T, Bian Z, Zhao B, Hogdal LJ, Sensintaffar JL, Goodwin CM, Belmar J, Shaw S, Tarr JC, Veerasamy N, Matulis SM, Koss B, Fischer MA, Arnold AL, Camper DV, ... ... Opferman J, et al. Discovery and Biological Characterization of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors. Febs Letters. PMID 27878989 DOI: 10.1002/1873-3468.12497 |
0.473 |
|
| 2016 |
Radhakrishnan P, Ruh N, Harnoss JM, Kiss J, Mollenhauer M, Scherr AL, Platzer LK, Schmidt T, Podar K, Opferman JT, Weitz J, Schulze-Bergkamen H, Koehler BC, Ulrich A, Schneider M. Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells. Cancer Research. 76: 2219-30. PMID 26921340 DOI: 10.1158/0008-5472.Can-15-1474 |
0.41 |
|
| 2016 |
Bashari MH, Fan F, Vallet S, Sattler M, Arn M, Luckner-Minden C, Schulze-Bergkamen H, Zörnig I, Marme F, Schneeweiss A, Cardone MH, Opferman JT, Jäger D, Podar K. Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications. Breast Cancer Research : Bcr. 18: 26. PMID 26921175 DOI: 10.1186/S13058-016-0686-4 |
0.401 |
|
| 2016 |
Koss B, Ryan J, Budhraja A, Szarama K, Yang X, Bathina M, Cardone MH, Nikolovska-Coleska Z, Letai A, Opferman JT. Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines. Oncotarget. PMID 26862853 DOI: 10.18632/Oncotarget.7204 |
0.474 |
|
| 2015 |
Morgan JA, Lynch J, Panetta JC, Wang Y, Frase S, Bao J, Zheng J, Opferman JT, Janke L, Green DM, Chemaitilly W, Schuetz JD. Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death. Scientific Reports. 5: 16488. PMID 26576726 DOI: 10.1038/Srep16488 |
0.463 |
|
| 2015 |
Opferman JT. Attacking cancer's Achilles heel: antagonism of anti-apoptotic BCL-2 family members. The Febs Journal. PMID 26293580 DOI: 10.1111/Febs.13472 |
0.467 |
|
| 2015 |
Delbridge AR, Opferman JT, Grabow S, Strasser A. Antagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress. Blood. 125: 3273-80. PMID 25847014 DOI: 10.1182/Blood-2015-01-621250 |
0.4 |
|
| 2015 |
Li-Harms X, Milasta S, Lynch J, Wright C, Joshi A, Iyengar R, Neale G, Wang X, Wang YD, Prolla TA, Thompson JE, Opferman JT, Green DR, Schuetz J, Kundu M. Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice. Blood. 125: 162-74. PMID 25411424 DOI: 10.1182/Blood-2014-07-586396 |
0.381 |
|
| 2015 |
Bashari MH, Fan F, Vallet S, Arn M, Cardone MH, Beckhove P, Schneeweiss A, Sattler M, Opferman JT, Jäger D, Podar K. Abstract A60: Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: Therapeutic implications Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-A60 |
0.456 |
|
| 2015 |
Omari S, Waters M, Naranian T, Kim K, Perumalsamy AL, Chi M, Greenblatt E, Moley KH, Opferman JT, Jurisicova A. MCL-1 is a key regulator of the ovarian reserve Cell Death and Disease. 6. DOI: 10.1038/Cddis.2015.95 |
0.51 |
|
| 2014 |
Haverkamp JM, Smith AM, Weinlich R, Dillon CP, Qualls JE, Neale G, Koss B, Kim Y, Bronte V, Herold MJ, Green DR, Opferman JT, Murray PJ. Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways. Immunity. 41: 947-59. PMID 25500368 DOI: 10.1016/J.Immuni.2014.10.020 |
0.507 |
|
| 2014 |
Fan F, Tonon G, Bashari MH, Vallet S, Antonini E, Goldschmidt H, Schulze-Bergkamen H, Opferman JT, Sattler M, Anderson KC, Jäger D, Podar K. Targeting Mcl-1 for multiple myeloma (MM) therapy: drug-induced generation of Mcl-1 fragment Mcl-1(128-350) triggers MM cell death via c-Jun upregulation. Cancer Letters. 343: 286-94. PMID 24120758 DOI: 10.1016/J.Canlet.2013.09.042 |
0.442 |
|
| 2013 |
Koss B, Morrison J, Perciavalle RM, Singh H, Rehg JE, Williams RT, Opferman JT. Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia. Blood. 122: 1587-98. PMID 23881917 DOI: 10.1182/Blood-2012-06-440230 |
0.707 |
|
| 2013 |
Hasan SM, Sheen AD, Power AM, Langevin LM, Xiong J, Furlong M, Day K, Schuurmans C, Opferman JT, Vanderluit JL. Mcl1 regulates the terminal mitosis of neural precursor cells in the mammalian brain through p27Kip1. Development (Cambridge, England). 140: 3118-27. PMID 23824576 DOI: 10.1242/Dev.090910 |
0.444 |
|
| 2013 |
Wang X, Bathina M, Lynch J, Koss B, Calabrese C, Frase S, Schuetz JD, Rehg JE, Opferman JT. Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction. Genes & Development. 27: 1351-64. PMID 23788622 DOI: 10.1101/Gad.215855.113 |
0.424 |
|
| 2013 |
Tripathi P, Koss B, Opferman JT, Hildeman DA. Mcl-1 antagonizes Bax/Bak to promote effector CD4(+) and CD8(+) T-cell responses. Cell Death and Differentiation. 20: 998-1007. PMID 23558951 DOI: 10.1038/Cdd.2013.25 |
0.434 |
|
| 2013 |
Perciavalle RM, Opferman JT. Delving deeper: MCL-1's contributions to normal and cancer biology. Trends in Cell Biology. 23: 22-9. PMID 23026029 DOI: 10.1016/J.Tcb.2012.08.011 |
0.735 |
|
| 2013 |
Bellairs JA, Reyna D, Sethumadhavan D, Neelagiri M, Broadhead A, Baccei C, Koss B, Opferman JT, Gavathiotis E, Walensky LD. Abstract 2471: Chemical optimization of direct and selective molecular activators of pro-apoptotic BAX for cancer therapy. Cancer Research. 73: 2471-2471. DOI: 10.1158/1538-7445.Am2013-2471 |
0.465 |
|
| 2013 |
Richard DJ, Carlson N, Pierceall W, Lena R, Bannister T, Hodder P, Spicer T, Andreeff M, Opferman J, Koss B, Kung A, Cardone M. Abstract 2466: Characterization and development of on-target Mcl-1 inhibitors; BH3 profiling provides a valuable drug discovery tool. Cancer Research. 73: 2466-2466. DOI: 10.1158/1538-7445.Am2013-2466 |
0.479 |
|
| 2013 |
Fan F, Tonon G, Sattler M, Goldschmidt H, Opferman J, Anderson KC, Jäger D, Podar K. Abstract 1734: Drug- induced generation of Mcl-1128-350fragment triggers apoptosis in multiple myeloma cells through upregulation of c-Jun. Cancer Research. 73: 1734-1734. DOI: 10.1158/1538-7445.Am2013-1734 |
0.463 |
|
| 2012 |
Cohen NA, Stewart ML, Gavathiotis E, Tepper JL, Bruekner SR, Koss B, Opferman JT, Walensky LD. A competitive stapled peptide screen identifies a selective small molecule that overcomes MCL-1-dependent leukemia cell survival. Chemistry & Biology. 19: 1175-86. PMID 22999885 DOI: 10.1016/J.Chembiol.2012.07.018 |
0.466 |
|
| 2012 |
Perciavalle RM, Stewart DP, Koss B, Lynch J, Milasta S, Bathina M, Temirov J, Cleland MM, Pelletier S, Schuetz JD, Youle RJ, Green DR, Opferman JT. Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration Nature Cell Biology. 14: 575-583. PMID 22544066 DOI: 10.1038/Ncb2488 |
0.731 |
|
| 2012 |
Malone CD, Hasan SM, Roome RB, Xiong J, Furlong M, Opferman JT, Vanderluit JL. Mcl-1 regulates the survival of adult neural precursor cells. Molecular and Cellular Neurosciences. 49: 439-47. PMID 22357134 DOI: 10.1016/J.Mcn.2012.02.003 |
0.396 |
|
| 2012 |
Garrison SP, Phillips DC, Jeffers JR, Chipuk JE, Parsons MJ, Rehg JE, Opferman JT, Green DR, Zambetti GP. Genetically defining the mechanism of Puma- and Bim-induced apoptosis. Cell Death and Differentiation. 19: 642-9. PMID 22015606 DOI: 10.1038/Cdd.2011.136 |
0.499 |
|
| 2012 |
Cohen NA, Stewart ML, Gavathiotis E, Tepper JL, Opferman JT, Walensky LD. Abstract 4851: Selective small molecule inhibition of anti-apoptotic MCL-1 Cancer Research. 72: 4851-4851. DOI: 10.1158/1538-7445.Am2012-4851 |
0.472 |
|
| 2011 |
Germain M, Nguyen AP, Le Grand JN, Arbour N, Vanderluit JL, Park DS, Opferman JT, Slack RS. MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. The Embo Journal. 30: 395-407. PMID 21139567 DOI: 10.1038/Emboj.2010.327 |
0.472 |
|
| 2011 |
Olsson HA, Plassard A, Dexheimer P, Phelan JD, Melnick A, Xia J, Link DC, Opferman J, Aronow BJ, Grimes HL. Conserved Transcriptional Deregulation Underlies GFI1 and ELANE Mutant Neutropenia Blood. 118: 13-13. DOI: 10.1182/Blood.V118.21.13.13 |
0.385 |
|
| 2010 |
Kurtulus S, Tripathi P, Opferman JT, Hildeman DA. Contracting the 'mus cells'--does down-sizing suit us for diving into the memory pool? Immunological Reviews. 236: 54-67. PMID 20636808 DOI: 10.1111/J.1600-065X.2010.00920.X |
0.422 |
|
| 2010 |
Xiang Z, Luo H, Payton JE, Cain J, Ley TJ, Opferman JT, Tomasson MH. Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia. The Journal of Clinical Investigation. 120: 2109-18. PMID 20484815 DOI: 10.1182/Blood.V114.22.764.764 |
0.495 |
|
| 2010 |
Stewart DP, Koss B, Bathina M, Perciavalle RM, Bisanz K, Opferman JT. Ubiquitin-independent degradation of antiapoptotic MCL-1. Molecular and Cellular Biology. 30: 3099-110. PMID 20385764 DOI: 10.1128/Mcb.01266-09 |
0.714 |
|
| 2010 |
Opferman JT, Green DR. DUB-le Trouble for Cell Survival. Cancer Cell. 17: 117-9. PMID 20159606 DOI: 10.1016/J.Ccr.2010.01.011 |
0.447 |
|
| 2010 |
Weber A, Boger R, Vick B, Urbanik T, Haybaeck J, Zoller S, Teufel A, Krammer PH, Opferman JT, Galle PR, Schuchmann M, Heikenwalder M, Schulze-Bergkamen H. Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice. Hepatology (Baltimore, Md.). 51: 1226-36. PMID 20099303 DOI: 10.1002/Hep.23479 |
0.388 |
|
| 2009 |
Brunelle JK, Ryan J, Yecies D, Opferman JT, Letai A. MCL-1-dependent leukemia cells are more sensitive to chemotherapy than BCL-2-dependent counterparts. The Journal of Cell Biology. 187: 429-42. PMID 19948485 DOI: 10.1083/Jcb.200904049 |
0.505 |
|
| 2009 |
Sano R, Annunziata I, Patterson A, Moshiach S, Gomero E, Opferman J, Forte M, d'Azzo A. GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis. Molecular Cell. 36: 500-11. PMID 19917257 DOI: 10.1016/J.Molcel.2009.10.021 |
0.367 |
|
| 2009 |
Vick B, Weber A, Urbanik T, Maass T, Teufel A, Krammer PH, Opferman JT, Schuchmann M, Galle PR, Schulze-Bergkamen H. Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes. Hepatology (Baltimore, Md.). 49: 627-36. PMID 19127517 DOI: 10.1002/Hep.22664 |
0.443 |
|
| 2009 |
Steimer DA, Boyd K, Takeuchi O, Fisher JK, Zambetti GP, Opferman JT. Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function. Blood. 113: 2805-15. PMID 19064728 DOI: 10.1182/Blood-2008-05-159145 |
0.427 |
|
| 2008 |
Arbour N, Vanderluit JL, Le Grand JN, Jahani-Asl A, Ruzhynsky VA, Cheung EC, Kelly MA, MacKenzie AE, Park DS, Opferman JT, Slack RS. Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6068-78. PMID 18550749 DOI: 10.1523/Jneurosci.4940-07.2008 |
0.379 |
|
| 2008 |
Chao JR, Parganas E, Boyd K, Hong CY, Opferman JT, Ihle JN. Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons. Nature. 452: 98-102. PMID 18288109 DOI: 10.1038/Nature06604 |
0.521 |
|
| 2008 |
Woodland RT, Fox CJ, Schmidt MR, Hammerman PS, Opferman JT, Korsmeyer SJ, Hilbert DM, Thompson CB. Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival. Blood. 111: 750-60. PMID 17942753 DOI: 10.1182/Blood-2007-03-077222 |
0.434 |
|
| 2008 |
Heidel FH, Schulze-Bergkamen H, Vick B, Lipka DB, Mirea FK, Urbanik T, Opferman JT, Fischer T. The Role of Mcl-1 Expression and Phosphorlyation in Resistance to Chemotherapy and Kinase Inhibitors in FLT3-ITD-Positive Acute Myeloid Leukemia (AML) Blood. 112: 220-220. DOI: 10.1182/Blood.V112.11.220.220 |
0.466 |
|
| 2007 |
Schweers RL, Zhang J, Randall MS, Loyd MR, Li W, Dorsey FC, Kundu M, Opferman JT, Cleveland JL, Miller JL, Ney PA. NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proceedings of the National Academy of Sciences of the United States of America. 104: 19500-5. PMID 18048346 DOI: 10.1073/Pnas.0708818104 |
0.45 |
|
| 2007 |
Opferman JT. Life and death during hematopoietic differentiation. Current Opinion in Immunology. 19: 497-502. PMID 17662585 DOI: 10.1016/J.Coi.2007.06.002 |
0.426 |
|
| 2007 |
Podar K, Gouill SL, Zhang J, Opferman JT, Zorn E, Tai YT, Hideshima T, Amiot M, Chauhan D, Harousseau JL, Anderson KC. A pivotal role for Mcl-1 in Bortezomib-induced apoptosis. Oncogene. 27: 721-31. PMID 17653083 DOI: 10.1038/sj.onc.1210679 |
0.38 |
|
| 2007 |
Opferman JT. Apoptosis in the development of the immune system. Cell Death and Differentiation. 15: 234-42. PMID 17571082 DOI: 10.1038/Sj.Cdd.4402182 |
0.437 |
|
| 2007 |
Luo H, Cain JA, Molitoris A, Opferman J, Tomasson MH. Myc Induces Acute Myeloid Leukemia by Conferring Self-Renewal Activity to Committed Myeloid Progenitor Cells That Resist Apoptosis Via Endogenous Mcl-1. Blood. 110: 2634-2634. DOI: 10.1182/Blood.V110.11.2634.2634 |
0.383 |
|
| 2006 |
Wei G, Twomey D, Lamb J, Schlis K, Agarwal J, Stam RW, Opferman JT, Sallan SE, den Boer ML, Pieters R, Golub TR, Armstrong SA. Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance. Cancer Cell. 10: 331-42. PMID 17010674 DOI: 10.1016/J.Ccr.2006.09.006 |
0.406 |
|
| 2006 |
Opferman JT, Zambetti GP. Translational research? Ribosome integrity and a new p53 tumor suppressor checkpoint Cell Death and Differentiation. 13: 898-901. PMID 16557265 DOI: 10.1038/Sj.Cdd.4401923 |
0.355 |
|
| 2005 |
Ruiz-Vela A, Opferman JT, Cheng EH, Korsmeyer SJ. Proapoptotic BAX and BAK control multiple initiator caspases. Embo Reports. 6: 379-85. PMID 15776018 DOI: 10.1038/Sj.Embor.7400375 |
0.434 |
|
| 2005 |
Opferman JT, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K, Korsmeyer SJ. Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. Science (New York, N.Y.). 307: 1101-4. PMID 15718471 DOI: 10.1126/Science.1106114 |
0.391 |
|
| 2005 |
Oakes SA, Scorrano L, Opferman JT, Bassik MC, Nishino M, Pozzan T, Korsmeyer SJ. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 102: 105-10. PMID 15613488 DOI: 10.1073/Pnas.0408352102 |
0.323 |
|
| 2005 |
Armstrong SA, Wei G, Lamb J, Opferman J, Twomey D, Stam R, den Boer M, Sallan SE, Pieters R, Golub TR. A Gene Expression Connectivity Map Identifies Rapamycin as a Glucocorticoid Resistance Reversal Agent in Lymphoblastic Leukemia. Blood. 106: 108-108. DOI: 10.1182/Blood.V106.11.108.108 |
0.429 |
|
| 2004 |
Phillips T, Opferman JT, Shah R, Liu N, Froelich CJ, Ashton-Rickardt PG. A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 173: 3801-9. PMID 15356127 DOI: 10.4049/Jimmunol.173.6.3801 |
0.36 |
|
| 2004 |
Liu N, Phillips T, Zhang M, Wang Y, Opferman JT, Shah R, Ashton-Rickardt PG. Serine protease inhibitor 2A is a protective factor for memory T cell development. Nature Immunology. 5: 919-26. PMID 15311278 DOI: 10.1038/Ni1107 |
0.343 |
|
| 2004 |
Mori M, Burgess DL, Gefrides LA, Foreman PJ, Opferman JT, Korsmeyer SJ, Cavalheiro EA, Naffah-Mazzacoratti MG, Noebels JL. Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons. Cell Death and Differentiation. 11: 1223-33. PMID 15286683 DOI: 10.1038/Sj.Cdd.4401483 |
0.356 |
|
| 2003 |
Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC, Korsmeyer SJ. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature. 426: 671-6. PMID 14668867 DOI: 10.1038/Nature02067 |
0.392 |
|
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