Brian P. Helmke - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Biomedical Engineering, Cell Biology

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Stadler RV, White LA, Hu K, Helmke BP, Guilford WH. Direct measurement of cortical force generation and polarization in a living parasite. Molecular Biology of the Cell. PMID 28209732 DOI: 10.1091/Mbc.E16-07-0518  0.403
2015 Wang CW, Perez MJ, Helmke BP, Viola F, Lawrence MB. Integration of acoustic radiation force and optical imaging for blood plasma clot stiffness measurement. Plos One. 10: e0128799. PMID 26042775 DOI: 10.1371/Journal.Pone.0128799  0.3
2015 Huang L, Helmke BP. Polarized actin structural dynamics in response to cyclic uniaxial stretch. Cellular and Molecular Bioengineering. 8: 160-177. PMID 25821527 DOI: 10.1007/S12195-014-0370-7  0.688
2014 Stadler RV, White LA, Helmke BP, Hu K, Guilford WH. Measuring Actomyosin Function in a Living Parasite using a Laser Trap Biophysical Journal. 106: 787a. DOI: 10.1016/J.Bpj.2013.11.4313  0.437
2012 Evans RE, Helmke BP. Fibronectin Matrix Assembly Regulates Shear Stress-Induced Structural Remodeling and Motility Biophysical Journal. 102: 705a. DOI: 10.1016/J.Bpj.2011.11.3827  0.48
2011 Huang L, Helmke BP. A Semi-Automatic Method for Image Analysis of Edge Dynamics in Living Cells. Cellular and Molecular Bioengineering. 4: 205-219. PMID 21643526 DOI: 10.1007/S12195-010-0141-Z  0.692
2011 Lin-Schmidt X, Ham A, Reed M, Lawrence M, Helmke B. Leukocyte rolling on engineered nanodot surfaces Micro & Nano Letters. 6: 301. DOI: 10.1049/Mnl.2011.0184  0.415
2010 Huang L, Mathieu PS, Helmke BP. A stretching device for high-resolution live-cell imaging. Annals of Biomedical Engineering. 38: 1728-40. PMID 20195762 DOI: 10.1007/S10439-010-9968-7  0.693
2010 Huang L, Mathieu PS, Helmke BP. Mechanical Coupling through Endothelial Cell Adhesions Determined Using a Novel Live-Cell Strain Device Biophysical Journal. 98: 729a. DOI: 10.1016/J.Bpj.2009.12.3996  0.712
2009 Lin X, Helmke BP. Cell Structure Controls Endothelial Cell Migration under Fluid Shear Stress. Cellular and Molecular Bioengineering. 2: 231-243. PMID 23181134 DOI: 10.1007/S12195-009-0060-Z  0.661
2009 Zawislak JD, Kolasinski KW, Helmke BP. Development of endothelial cells on pillar-covered silicon Physica Status Solidi (a) Applications and Materials Science. 206: 1356-1360. DOI: 10.1002/Pssa.200881037  0.468
2008 Choi CK, Helmke BP. Short-Term Shear Stress Induces Rapid Actin Dynamics in Living Endothelial Cells. Molecular & Cellular Biomechanics : McB. 5: 247-258. PMID 20084179  0.431
2008 Helmke BP. Choosing sides in polarized endothelial adaptation to shear stress. Circulation Research. 103: 122-4. PMID 18635827 DOI: 10.1161/Circresaha.108.180836  0.497
2008 Lin X, Helmke BP. Micropatterned structural control suppresses mechanotaxis of endothelial cells. Biophysical Journal. 95: 3066-78. PMID 18586851 DOI: 10.1529/Biophysj.107.127761  0.662
2008 Snook JH, Li J, Helmke BP, Guilford WH. Peroxynitrite inhibits myofibrillar protein function in an in vitro assay of motility. Free Radical Biology & Medicine. 44: 14-23. PMID 18045543 DOI: 10.1016/J.Freeradbiomed.2007.09.004  0.313
2007 Helmke BP, Davies PF. Chambers for Examination of Live Cells under Mechanical Stress. Csh Protocols. 2007: pdb.ip32. PMID 21357009 DOI: 10.1101/Pdb.Ip32  0.44
2007 Mott RE, Helmke BP. Mapping the dynamics of shear stress-induced structural changes in endothelial cells. American Journal of Physiology. Cell Physiology. 293: C1616-26. PMID 17855768 DOI: 10.1152/Ajpcell.00457.2006  0.493
2006 Helmke BP, Minerick AR. Designing a nano-interface in a microfluidic chip to probe living cells: challenges and perspectives. Proceedings of the National Academy of Sciences of the United States of America. 103: 6419-24. PMID 16618928 DOI: 10.1073/Pnas.0507304103  0.369
2006 Sinha S, Wamhoff BR, Hoofnagle MH, Thomas J, Neppl RL, Deering T, Helmke BP, Bowles DK, Somlyo AV, Owens GK. Assessment of contractility of purified smooth muscle cells derived from embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 1678-88. PMID 16601077 DOI: 10.1634/Stemcells.2006-0002  0.371
2006 Orr AW, Helmke BP, Blackman BR, Schwartz MA. Mechanisms of mechanotransduction. Developmental Cell. 10: 11-20. PMID 16399074 DOI: 10.1016/J.Devcel.2005.12.006  0.318
2006 DeLisser HM, Helmke BP, Cao G, Egan PM, Taichman D, Fehrenbach M, Zaman A, Cui Z, Mohan GS, Baldwin HS, Davies PF, Savani RC. Loss of PECAM-1 function impairs alveolarization. The Journal of Biological Chemistry. 281: 8724-31. PMID 16377626 DOI: 10.1074/Jbc.M511798200  0.36
2006 Lin X, Ham A, Reed M, Lawrence M, Helmke B. Shear stress dependence of leukocyte rolling interactions on nanopatterned substrates of P-selectin that mimic activated endothelial surfaces Journal of Biomechanics. 39: S337. DOI: 10.1016/S0021-9290(06)84336-8  0.355
2006 Mott RE, Helmke BP. Control of endothelial cell adhesion by mechanotransmission from cytoskeleton to substrate Principles of Cellular Engineering. 25-50. DOI: 10.1016/B978-012369392-1/50003-6  0.35
2005 Helmke BP. Molecular control of cytoskeletal mechanics by hemodynamic forces. Physiology (Bethesda, Md.). 20: 43-53. PMID 15653839 DOI: 10.1152/Physiol.00040.2004  0.414
2004 Mott RE, Helmke BP. STRUCTURAL REMODELING IN ENDOTHELIAL CELLS IN RESPONSE TO SHEAR STRESS Cardiovascular Pathology. 13: 192. DOI: 10.1016/J.Carpath.2004.03.577  0.455
2004 Helmke BP, Choi CK, Mott RE. SUBCELLULAR IMAGING OF ENDOTHELIAL MECHANOCHEMICAL DYNAMICS Cardiovascular Pathology. 13: 14. DOI: 10.1016/J.Carpath.2004.03.035  0.338
2003 Helmke BP, Rosen AB, Davies PF. Mapping mechanical strain of an endogenous cytoskeletal network in living endothelial cells. Biophysical Journal. 84: 2691-9. PMID 12668477 DOI: 10.1016/S0006-3495(03)75074-7  0.509
2003 Davies PF, Zilberberg J, Helmke BP. Spatial microstimuli in endothelial mechanosignaling. Circulation Research. 92: 359-70. PMID 12623874 DOI: 10.1161/01.Res.0000060201.41923.88  0.488
2003 Lin X, Ham ASW, Villani NA, Lye W, Huang Q, Lawrence MB, Helmke BP, Reed ML. Fabrication of Nanoscale Hydrophobic Regions on Anodic Alumina for Selective Adhesion of Biologic Molecules Mrs Proceedings. 773. DOI: 10.1557/PROC-773-N6.3  0.304
2002 Helmke BP, Davies PF. The cytoskeleton under external fluid mechanical forces: hemodynamic forces acting on the endothelium. Annals of Biomedical Engineering. 30: 284-96. PMID 12051614 DOI: 10.1114/1.1467926  0.406
2002 Zhang JC, Helmke BP, Shum A, Du K, Yu WW, Lu MM, Davies PF, Parmacek MS. SM22beta encodes a lineage-restricted cytoskeletal protein with a unique developmentally regulated pattern of expression. Mechanisms of Development. 115: 161-6. PMID 12049783 DOI: 10.1016/S0925-4773(02)00088-6  0.346
2001 Helmke BP, Thakker DB, Goldman RD, Davies PF. Spatiotemporal analysis of flow-induced intermediate filament displacement in living endothelial cells. Biophysical Journal. 80: 184-94. PMID 11159394 DOI: 10.1016/S0006-3495(01)76006-7  0.449
2001 Zhang JC, Kim S, Helmke BP, Yu WW, Du KL, Lu MM, Strobeck M, Yu Q, Parmacek MS. Analysis of SM22alpha-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function. Molecular and Cellular Biology. 21: 1336-44. PMID 11158319 DOI: 10.1128/Mcb.2001.21.4.1336-1344.2001  0.325
2000 Levitan I, Helmke BP, Davies PF. A chamber to permit invasive manipulation of adherent cells in laminar flow with minimal disturbance of the flow field. Annals of Biomedical Engineering. 28: 1184-93. PMID 11144979 DOI: 10.1114/1.1317529  0.322
2000 Helmke BP, Goldman RD, Davies PF. Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow Circulation Research. 86: 745-752. PMID 10764407 DOI: 10.1161/01.Res.86.7.745  0.412
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