| Year |
Citation |
Score |
| 2023 |
Lim TY, Wilde BR, Thomas ML, Murphy KE, Vahrenkamp JM, Conway ME, Varley KE, Gertz J, Ayer DE. TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding. Plos Biology. 21: e3001778. PMID 36930677 DOI: 10.1371/journal.pbio.3001778 |
0.352 |
|
| 2021 |
Carroll PA, Freie BW, Cheng PF, Kasinathan S, Gu H, Hedrich T, Dowdle JA, Venkataramani V, Ramani V, Wu X, Raftery D, Shendure J, Ayer DE, Muller CH, Eisenman RN. The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis. Plos Biology. 19: e3001085. PMID 34669700 DOI: 10.1371/journal.pbio.3001085 |
0.585 |
|
| 2020 |
Wilde BR, Kaadige MR, Guillen KP, Butterfield A, Welm BE, Ayer DE. Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate. Cancer & Metabolism. 8: 27. PMID 33292639 DOI: 10.1186/s40170-020-00233-6 |
0.322 |
|
| 2019 |
Ahn B, Wan S, Jaiswal N, Vega RB, Ayer DE, Titchenell PM, Han X, Won KJ, Kelly DP. MondoA drives muscle lipid accumulation and insulin resistance. Jci Insight. 5. PMID 31287806 DOI: 10.1172/Jci.Insight.129119 |
0.306 |
|
| 2019 |
Wilde BR, Ye Z, Lim TY, Ayer DE. Cellular acidosis triggers human MondoA transcriptional activity by driving mitochondrial ATP production. Elife. 8. PMID 30717828 DOI: 10.7554/Elife.40199 |
0.382 |
|
| 2018 |
Sullivan WJ, Mullen PJ, Schmid EW, Flores A, Momcilovic M, Sharpley MS, Jelinek D, Whiteley AE, Maxwell MB, Wilde BR, Banerjee U, Coller HA, Shackelford DB, Braas D, Ayer DE, et al. Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. Cell. PMID 30197082 DOI: 10.1016/J.Cell.2018.08.017 |
0.375 |
|
| 2018 |
Ye Z, Ayer DE. Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation. Molecular and Cellular Biology. PMID 30037981 DOI: 10.1128/Mcb.00178-18 |
0.365 |
|
| 2018 |
Schaub FX, Dhankani V, Berger AC, Trivedi M, Richardson AB, Shaw R, Zhao W, Zhang X, Ventura A, Liu Y, Ayer DE, Hurlin PJ, Cherniack AD, Eisenman RN, Bernard B, et al. Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Systems. 6: 282-300.e2. PMID 29596783 DOI: 10.1016/J.Cels.2018.03.003 |
0.581 |
|
| 2018 |
Wilde BR, Ye Z, Lim T, Ayer DE. Author response: Cellular acidosis triggers human MondoA transcriptional activity by driving mitochondrial ATP production Elife. DOI: 10.7554/Elife.40199.025 |
0.309 |
|
| 2017 |
Ye Z, Ayer DE. Abstract B48: Oncogenic Ras reprograms metabolism by suppressing TXNIP translation Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-B48 |
0.359 |
|
| 2016 |
Carroll PA, Diolaiti D, Cheng P, Gu H, Djukovic D, Raftery D, Ayer DE, Muller CH, Eisenman RN. Abstract PR12: Transcriptional regulation of metabolism by MLX and its binding partners is essential for tumor cell survival and spermatogenesis Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-Pr12 |
0.657 |
|
| 2016 |
Carroll PA, Cheng P, Muller CH, Hunt L, Demontis F, Ayer DE, Eisenman RN. Abstract PL02-02: Transcriptional regulation by the MAX-like protein MLX is required for adaptive metabolic responses in development and tumorigenesis Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Pl02-02 |
0.632 |
|
| 2015 |
Wilde BR, Ayer DE. Interactions between Myc and MondoA transcription factors in metabolism and tumourigenesis. British Journal of Cancer. 113: 1529-33. PMID 26469830 DOI: 10.1038/Bjc.2015.360 |
0.434 |
|
| 2015 |
Shen L, O'Shea JM, Kaadige MR, Cunha S, Wilde BR, Cohen AL, Welm AL, Ayer DE. Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP. Proceedings of the National Academy of Sciences of the United States of America. 112: 5425-30. PMID 25870263 DOI: 10.1073/Pnas.1501555112 |
0.39 |
|
| 2015 |
Carroll PA, Diolaiti D, McFerrin L, Gu H, Djukovic D, Du J, Cheng PF, Anderson S, Ulrich M, Hurley JB, Raftery D, Ayer DE, Eisenman RN. Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis. Cancer Cell. 27: 271-85. PMID 25640402 DOI: 10.1016/J.Ccell.2014.11.024 |
0.611 |
|
| 2015 |
Kaadige MR, Yang J, Wilde BR, Ayer DE. MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction. Molecular and Cellular Biology. 35: 101-10. PMID 25332233 DOI: 10.1128/Mcb.00636-14 |
0.508 |
|
| 2014 |
Bowman CJ, Ayer DE, Dynlacht BD. Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. Nature Cell Biology. 16: 1202-14. PMID 25402684 DOI: 10.1038/Ncb3062 |
0.492 |
|
| 2014 |
Parmenter TJ, Kleinschmidt M, Kinross KM, Bond ST, Li J, Kaadige MR, Rao A, Sheppard KE, Hugo W, Pupo GM, Pearson RB, McGee SL, Long GV, Scolyer RA, Rizos H, ... ... Ayer DE, et al. Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis. Cancer Discovery. 4: 423-33. PMID 24469106 DOI: 10.1158/2159-8290.Cd-13-0440 |
0.393 |
|
| 2013 |
O'Shea JM, Ayer DE. Coordination of nutrient availability and utilization by MAX- and MLX-centered transcription networks. Cold Spring Harbor Perspectives in Medicine. 3: a014258. PMID 24003245 DOI: 10.1101/Cshperspect.A014258 |
0.392 |
|
| 2013 |
Han KS, Ayer DE. MondoA senses adenine nucleotides: transcriptional induction of thioredoxin-interacting protein. The Biochemical Journal. 453: 209-18. PMID 23631812 DOI: 10.1042/Bj20121126 |
0.434 |
|
| 2011 |
Stoltzman CA, Kaadige MR, Peterson CW, Ayer DE. MondoA senses non-glucose sugars: regulation of thioredoxin-interacting protein (TXNIP) and the hexose transport curb. The Journal of Biological Chemistry. 286: 38027-34. PMID 21908621 DOI: 10.1074/Jbc.M111.275503 |
0.385 |
|
| 2011 |
Peterson CW, Ayer DE. An extended Myc network contributes to glucose homeostasis in cancer and diabetes. Frontiers in Bioscience (Landmark Edition). 16: 2206-23. PMID 21622171 DOI: 10.2741/3848 |
0.413 |
|
| 2010 |
Elgort MG, O'Shea JM, Jiang Y, Ayer DE. Transcriptional and Translational Downregulation of Thioredoxin Interacting Protein Is Required for Metabolic Reprogramming during G(1). Genes & Cancer. 1: 893-907. PMID 21779470 DOI: 10.1177/1947601910389604 |
0.761 |
|
| 2010 |
Kaadige MR, Elgort MG, Ayer DE. Coordination of glucose and glutamine utilization by an expanded Myc network. Transcription. 1: 36-40. PMID 21327161 DOI: 10.4161/trns.1.1.12142 |
0.708 |
|
| 2010 |
Sloan EJ, Ayer DE. Myc, mondo, and metabolism. Genes & Cancer. 1: 587-96. PMID 21113411 DOI: 10.1177/1947601910377489 |
0.485 |
|
| 2010 |
Chen JL, Merl D, Peterson CW, Wu J, Liu PY, Yin H, Muoio DM, Ayer DE, West M, Chi JT. Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. Plos Genetics. 6: e1001093. PMID 20844768 DOI: 10.1371/Journal.Pgen.1001093 |
0.37 |
|
| 2010 |
Peterson CW, Stoltzman CA, Sighinolfi MP, Han KS, Ayer DE. Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer. Molecular and Cellular Biology. 30: 2887-95. PMID 20385767 DOI: 10.1128/Mcb.01613-09 |
0.434 |
|
| 2010 |
Julia LC, Merl D, Peterson C, Wu J, Liu PY, West M, Ayer D, Chi J. Abstract 2340: Lactic acidosis triggers starvation response with distinct metabolic profiles by the induction of TXNIP through MondoA Cancer Research. 70: 2340-2340. DOI: 10.1158/1538-7445.Am10-2340 |
0.359 |
|
| 2009 |
Kaadige MR, Looper RE, Kamalanaadhan S, Ayer DE. Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity. Proceedings of the National Academy of Sciences of the United States of America. 106: 14878-83. PMID 19706488 DOI: 10.1073/Pnas.0901221106 |
0.426 |
|
| 2009 |
Silveira AC, Hurst DR, Vaidya KS, Ayer DE, Welch DR. Over-expression of the BRMS1 family member SUDS3 does not suppress metastasis of human cancer cells. Cancer Letters. 276: 32-7. PMID 19070953 DOI: 10.1016/J.Canlet.2008.10.024 |
0.388 |
|
| 2008 |
Stoltzman CA, Peterson CW, Breen KT, Muoio DM, Billin AN, Ayer DE. Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. Proceedings of the National Academy of Sciences of the United States of America. 105: 6912-7. PMID 18458340 DOI: 10.1073/Pnas.0712199105 |
0.431 |
|
| 2007 |
Pickett CL, Breen KT, Ayer DE. A C. elegans Myc-like network cooperates with semaphorin and Wnt signaling pathways to control cell migration. Developmental Biology. 310: 226-39. PMID 17826759 DOI: 10.1016/J.Ydbio.2007.07.034 |
0.485 |
|
| 2006 |
Kaadige MR, Ayer DE. The polybasic region that follows the plant homeodomain zinc finger 1 of Pf1 is necessary and sufficient for specific phosphoinositide binding. The Journal of Biological Chemistry. 281: 28831-6. PMID 16893883 DOI: 10.1074/Jbc.M605624200 |
0.427 |
|
| 2006 |
Sans CL, Satterwhite DJ, Stoltzman CA, Breen KT, Ayer DE. MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis. Molecular and Cellular Biology. 26: 4863-71. PMID 16782875 DOI: 10.1128/Mcb.00657-05 |
0.484 |
|
| 2006 |
Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, ... Ayer DE, et al. ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature. 442: 96-9. PMID 16728974 DOI: 10.1038/Nature04835 |
0.506 |
|
| 2006 |
Billin AN, Ayer DE. The Mlx network: evidence for a parallel Max-like transcriptional network that regulates energy metabolism. Current Topics in Microbiology and Immunology. 302: 255-78. PMID 16620032 DOI: 10.1007/3-540-32952-8_10 |
0.475 |
|
| 2003 |
Fleischer TC, Yun UJ, Ayer DE. Identification and characterization of three new components of the mSin3A corepressor complex. Molecular and Cellular Biology. 23: 3456-67. PMID 12724404 DOI: 10.1128/Mcb.23.10.3456-3467.2003 |
0.778 |
|
| 2002 |
Eilers AL, Sundwall E, Lin M, Sullivan AA, Ayer DE. A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex. Molecular and Cellular Biology. 22: 8514-26. PMID 12446771 DOI: 10.1128/Mcb.22.24.8514-8526.2002 |
0.763 |
|
| 2002 |
Yochum GS, Ayer DE. Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split. Molecular and Cellular Biology. 22: 7868-76. PMID 12391155 DOI: 10.1128/Mcb.22.22.7868-7876.2002 |
0.757 |
|
| 2001 |
Yochum GS, Ayer DE. Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex. Molecular and Cellular Biology. 21: 4110-8. PMID 11390640 DOI: 10.1128/Mcb.21.13.4110-4118.2001 |
0.749 |
|
| 2000 |
Brubaker K, Cowley SM, Huang K, Loo L, Yochum GS, Ayer DE, Eisenman RN, Radhakrishnan I. Solution structure of the interacting domains of the Mad-Sin3 complex: implications for recruitment of a chromatin-modifying complex. Cell. 103: 655-65. PMID 11106735 DOI: 10.1016/S0092-8674(00)00168-9 |
0.757 |
|
| 2000 |
Billin AN, Eilers AL, Coulter KL, Logan JS, Ayer DE. MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network. Molecular and Cellular Biology. 20: 8845-54. PMID 11073985 DOI: 10.1128/Mcb.20.23.8845-8854.2000 |
0.8 |
|
| 2000 |
Billin AN, Thirlwell H, Ayer DE. Beta-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator. Molecular and Cellular Biology. 20: 6882-90. PMID 10958684 DOI: 10.1128/Mcb.20.18.6882-6890.2000 |
0.394 |
|
| 1999 |
Billin AN, Eilers AL, Queva C, Ayer DE. Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors. The Journal of Biological Chemistry. 274: 36344-50. PMID 10593926 DOI: 10.1074/Jbc.274.51.36344 |
0.8 |
|
| 1999 |
Eilers AL, Billin AN, Liu J, Ayer DE. A 13-amino acid amphipathic alpha-helix is required for the functional interaction between the transcriptional repressor Mad1 and mSin3A. The Journal of Biological Chemistry. 274: 32750-6. PMID 10551834 DOI: 10.1074/Jbc.274.46.32750 |
0.784 |
|
| 1999 |
Ayer DE. Histone deacetylases: transcriptional repression with SINers and NuRDs. Trends in Cell Biology. 9: 193-8. PMID 10322454 DOI: 10.1016/S0962-8924(99)01536-6 |
0.467 |
|
| 1998 |
McArthur GA, Laherty CD, Quéva C, Hurlin PJ, Loo L, James L, Grandori C, Gallant P, Shiio Y, Hokanson WC, Bush AC, Cheng PF, Lawrence QA, Pulverer B, Koskinen PJ, ... ... Ayer DE, et al. The Mad protein family links transcriptional repression to cell differentiation. Cold Spring Harbor Symposia On Quantitative Biology. 63: 423-33. PMID 10384307 DOI: 10.1101/Sqb.1998.63.423 |
0.791 |
|
| 1998 |
Laherty CD, Billin AN, Lavinsky RM, Yochum GS, Bush AC, Sun JM, Mullen TM, Davie JR, Rose DW, Glass CK, Rosenfeld MG, Ayer DE, Eisenman RN. SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Molecular Cell. 2: 33-42. PMID 9702189 DOI: 10.1016/S1097-2765(00)80111-2 |
0.764 |
|
| 1998 |
Hassig CA, Tong JK, Fleischer TC, Owa T, Grable PG, Ayer DE, Schreiber SL. A role for histone deacetylase activity in HDAC1-mediated transcriptional repression. Proceedings of the National Academy of Sciences of the United States of America. 95: 3519-24. PMID 9520398 DOI: 10.1073/Pnas.95.7.3519 |
0.747 |
|
| 1997 |
Nagy L, Kao HY, Chakravarti D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell. 89: 373-80. PMID 9150137 DOI: 10.1016/S0092-8674(00)80218-4 |
0.5 |
|
| 1997 |
Hassig CA, Fleischer TC, Billin AN, Schreiber SL, Ayer DE. Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell. 89: 341-7. PMID 9150133 DOI: 10.1016/S0092-8674(00)80214-7 |
0.781 |
|
| 1996 |
Ayer DE, Laherty CD, Lawrence QA, Armstrong AP, Eisenman RN. Mad proteins contain a dominant transcription repression domain. Molecular and Cellular Biology. 16: 5772-81. PMID 8816491 DOI: 10.1128/Mcb.16.10.5772 |
0.716 |
|
| 1996 |
Kasten MM, Ayer DE, Stillman DJ. SIN3-dependent transcriptional repression by interaction with the Mad1 DNA-binding protein. Molecular and Cellular Biology. 16: 4215-21. PMID 8754821 DOI: 10.1128/Mcb.16.8.4215 |
0.547 |
|
| 1996 |
Roussel MF, Ashmun RA, Sherr CJ, Eisenman RN, Ayer DE. Inhibition of cell proliferation by the Mad1 transcriptional repressor. Molecular and Cellular Biology. 16: 2796-801. PMID 8649388 DOI: 10.1128/Mcb.16.6.2796 |
0.636 |
|
| 1996 |
Grandori C, Mac J, Siëbelt F, Ayer DE, Eisenman RN. Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo. The Embo Journal. 15: 4344-4357. DOI: 10.1002/J.1460-2075.1996.Tb00808.X |
0.678 |
|
| 1996 |
Hurlin PJ, Quéva C, Koskinen PJ, Steingrímsson E, Ayer DE, Copeland NG, Jenkins NA, Eisenman RN. Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. The Embo Journal. 15: 2030-2030. DOI: 10.1002/j.1460-2075.1996.tb00555.x |
0.579 |
|
| 1995 |
Ayer DE, Lawrence QA, Eisenman RN. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell. 80: 767-76. PMID 7889570 DOI: 10.1016/0092-8674(95)90355-0 |
0.726 |
|
| 1995 |
Hurlin PJ, Ayer DE, Grandori C, Eisenman RN. The Max transcription factor network: involvement of Mad in differentiation and an approach to identification of target genes. Cold Spring Harbor Symposia On Quantitative Biology. 59: 109-16. PMID 7587059 DOI: 10.1101/Sqb.1994.059.01.014 |
0.704 |
|
| 1995 |
Hurlin PJ, Quéva C, Koskinen PJ, Steingrímsson E, Ayer DE, Copeland NG, Jenkins NA, Eisenman RN. Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. The Embo Journal. 14: 5646-5659. DOI: 10.1002/J.1460-2075.1995.Tb00252.X |
0.699 |
|
| 1993 |
Ayer DE, Kretzner L, Eisenman RN. Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell. 72: 211-22. PMID 8425218 DOI: 10.1016/0092-8674(93)90661-9 |
0.712 |
|
| 1993 |
Ayer DE, Eisenman RN. A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation. Genes & Development. 7: 2110-9. PMID 8224841 DOI: 10.1101/Gad.7.11.2110 |
0.687 |
|
| 1990 |
Ayer DE, Dynan WS. A Downstream-Element-Binding Factor Facilitates Assembly of a Functional Preinitiation Complex at the Simian Virus 40 Major Late Promoter Molecular and Cellular Biology. 10: 3635-3645. PMID 2162478 DOI: 10.1128/Mcb.10.7.3635 |
0.684 |
|
| 1988 |
Ayer DE, Dynan WS. Simian virus 40 major late promoter: a novel tripartite structure that includes intragenic sequences Molecular and Cellular Biology. 8: 2021-2033. PMID 2838741 DOI: 10.1128/Mcb.8.5.2021 |
0.613 |
|
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