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Walter E. Mushynski, Ph.D. - Publications

Affiliations: 
Biochemistry McGill University, Montreal, QC, Canada 
Area:
Biochemistry, Neurofilaments
Website:
http://www.mcgill.ca/biochemistry/about-us-0/department/faculty-members/mushynski

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Gentil BJ, Mushynski WE, Durham HD. Heterogeneity in the properties of NEFL mutants causing Charcot-Marie-Tooth disease results in differential effects on neurofilament assembly and susceptibility to intervention by the chaperone-inducer, celastrol. The International Journal of Biochemistry & Cell Biology. 45: 1499-508. PMID 23618875 DOI: 10.1016/j.biocel.2013.04.009  0.92
2010 Cui QL, Fragoso G, Miron VE, Darlington PJ, Mushynski WE, Antel J, Almazan G. Response of human oligodendrocyte progenitors to growth factors and axon signals. Journal of Neuropathology and Experimental Neurology. 69: 930-44. PMID 20720504 DOI: 10.1097/NEN.0b013e3181ef3be4  0.92
2010 Hossain S, Fragoso G, Mushynski WE, Almazan G. Regulation of peripheral myelination by Src-like kinases. Experimental Neurology. 226: 47-57. PMID 20696161 DOI: 10.1016/j.expneurol.2010.08.002  0.92
2010 Haines JD, Fang J, Mushynski WE, Almazan G. Mitogen-activated protein kinase activated protein kinase 2 (MK2) participates in p38 MAPK regulated control of oligodendrocyte differentiation. Glia. 58: 1384-93. PMID 20607863 DOI: 10.1002/glia.21014  0.92
2009 Bruno MA, Leon WC, Fragoso G, Mushynski WE, Almazan G, Cuello AC. Amyloid beta-induced nerve growth factor dysmetabolism in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 68: 857-69. PMID 19606067 DOI: 10.1097/NEN.0b013e3181aed9e6  0.92
2009 Larocque D, Fragoso G, Huang J, Mushynski WE, Loignon M, Richard S, Almazan G. The QKI-6 and QKI-7 RNA binding proteins block proliferation and promote Schwann cell myelination. Plos One. 4: e5867. PMID 19517016 DOI: 10.1371/journal.pone.0005867  0.92
2009 Tradewell ML, Durham HD, Mushynski WE, Gentil BJ. Mitochondrial and axonal abnormalities precede disruption of the neurofilament network in a model of charcot-marie-tooth disease type 2E and are prevented by heat shock proteins in a mutant-specific fashion. Journal of Neuropathology and Experimental Neurology. 68: 642-52. PMID 19458545 DOI: 10.1097/NEN.0b013e3181a5deeb  0.92
2008 Haines JD, Fragoso G, Hossain S, Mushynski WE, Almazan G. p38 Mitogen-activated protein kinase regulates myelination. Journal of Molecular Neuroscience : Mn. 35: 23-33. PMID 17994198 DOI: 10.1007/s12031-007-9011-0  0.92
2007 Fragoso G, Haines JD, Roberston J, Pedraza L, Mushynski WE, Almazan G. p38 mitogen-activated protein kinase is required for central nervous system myelination. Glia. 55: 1531-41. PMID 17729284 DOI: 10.1002/glia.20567  0.92
2006 Jacomy H, Fragoso G, Almazan G, Mushynski WE, Talbot PJ. Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice. Virology. 349: 335-46. PMID 16527322 DOI: 10.1016/j.virol.2006.01.049  0.92
2004 Fragoso G, Martínez-Bermúdez AK, Liu HN, Khorchid A, Chemtob S, Mushynski WE, Almazan G. Developmental differences in HO-induced oligodendrocyte cell death: role of glutathione, mitogen-activated protein kinases and caspase 3. Journal of Neurochemistry. 90: 392-404. PMID 15228596 DOI: 10.1111/j.1471-4159.2004.02488.x  0.92
2003 Fragoso G, Robertson J, Athlan E, Tam E, Almazan G, Mushynski WE. Inhibition of p38 mitogen-activated protein kinase interferes with cell shape changes and gene expression associated with Schwann cell myelination. Experimental Neurology. 183: 34-46. PMID 12957486 DOI: 10.1016/S0014-4886(03)00101-8  0.92
2003 Robertson J, Doroudchi MM, Nguyen MD, Durham HD, Strong MJ, Shaw G, Julien JP, Mushynski WE. A neurotoxic peripherin splice variant in a mouse model of ALS. The Journal of Cell Biology. 160: 939-49. PMID 12642616 DOI: 10.1083/jcb.200205027  0.92
2002 Giasson BI, Sampathu DM, Wilson CA, Vogelsberg-Ragaglia V, Mushynski WE, Lee VM. The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry. 41: 15376-87. PMID 12484777 DOI: 10.1021/bi026813c  0.92
2002 Nguyen MD, Mushynski WE, Julien JP. Cycling at the interface between neurodevelopment and neurodegeneration. Cell Death and Differentiation. 9: 1294-306. PMID 12478466 DOI: 10.1038/sj.cdd.4401108  0.92
2002 Liu HN, Giasson BI, Mushynski WE, Almazan G. AMPA receptor-mediated toxicity in oligodendrocyte progenitors involves free radical generation and activation of JNK, calpain and caspase 3. Journal of Neurochemistry. 82: 398-409. PMID 12124441 DOI: 10.1046/j.1471-4159.2002.00981.x  0.92
2001 Robertson J, Beaulieu JM, Doroudchi MM, Durham HD, Julien JP, Mushynski WE. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. The Journal of Cell Biology. 155: 217-26. PMID 11604419 DOI: 10.1083/jcb.200107058  0.92
2000 O'Ferrall EK, Robertson J, Mushynski WE. Inhibition of aberrant and constitutive phosphorylation of the high-molecular-mass neurofilament subunit by CEP-1347 (KT7515), an inhibitor of the stress-activated protein kinase signaling pathway. Journal of Neurochemistry. 75: 2358-67. PMID 11080187 DOI: 10.1046/j.1471-4159.2000.0752358.x  0.92
1999 Giasson BI, Bruening W, Durham HD, Mushynski WE. Activation of stress-activated protein kinases correlates with neurite outgrowth induced by protease inhibition in PC12 cells. Journal of Neurochemistry. 72: 1081-7. PMID 10037479 DOI: 10.1046/j.1471-4159.1999.0721081.x  0.92
1999 Bruening W, Roy J, Giasson B, Figlewicz DA, Mushynski WE, Durham HD. Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis. Journal of Neurochemistry. 72: 693-9. PMID 9930742 DOI: 10.1046/j.1471-4159.1999.0720693.x  0.92
1998 Julien JP, Mushynski WE. Neurofilaments in health and disease. Progress in Nucleic Acid Research and Molecular Biology. 61: 1-23. PMID 9752717  0.92
1998 Giasson BI, Mushynski WE. Intermediate filament disassembly in cultured dorsal root ganglion neurons is associated with amino-terminal head domain phosphorylation of specific subunits. Journal of Neurochemistry. 70: 1869-75. PMID 9572270  0.92
1998 Bruening W, Giasson B, Mushynski W, Durham HD. Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter Nucleic Acids Research. 26: 486-489. PMID 9421504 DOI: 10.1093/nar/26.2.486  0.92
1997 Giasson BI, Mushynski WE. Study of proline-directed protein kinases involved in phosphorylation of the heavy neurofilament subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9466-72. PMID 9391002  0.92
1997 Athlan ES, Mushynski WE. Heterodimeric associations between neuronal intermediate filament proteins. The Journal of Biological Chemistry. 272: 31073-8. PMID 9388258 DOI: 10.1074/jbc.272.49.31073  0.92
1997 Giasson BI, Mushynski WE. Developmentally regulated stabilization of neuronal intermediate filaments in rat cerebral cortex. Neuroscience Letters. 229: 77-80. PMID 9223595 DOI: 10.1016/S0304-3940(97)00425-4  0.92
1997 Athlan ES, Sacher MG, Mushynski WE. Associations between intermediate filament proteins expressed in cultured dorsal root ganglion neurons. Journal of Neuroscience Research. 47: 300-10. PMID 9039652 DOI: 10.1002/(SICI)1097-4547(19970201)47:3<300::AID-JNR8>3.0.CO;2-M  0.92
1997 Giasson BI, Mushynski WE. Okadaic acid reversibly inhibits neurite outgrowth in embryonic dorsal root ganglion neurons. Journal of Neurobiology. 32: 193-201. PMID 9032661 DOI: 10.1002/(SICI)1097-4695(199702)32:2<193::AID-NEU4>3.0.CO;2-3  0.92
1996 Giasson BI, Mushynski WE. Aberrant stress-induced phosphorylation of perikaryal neurofilaments. The Journal of Biological Chemistry. 271: 30404-9. PMID 8940004 DOI: 10.1074/jbc.271.48.30404  0.92
1996 Giasson BI, Cromlish JA, Athlan ES, Mushynski WE. Activation of cyclic AMP-dependent protein kinase in okadaic acid-treated neurons potentiates neurofilament fragmentation and stimulates phosphorylation of Ser2 in the low-molecular-mass neurofilament subunit. Journal of Neurochemistry. 66: 1207-13. PMID 8769885  0.92
1995 Jayaraman D, Giasson BI, Mushynski WE. Increased phosphorylation of neurofilament subunits in PC12 cells and rat dorsal root ganglion neurons treated with N-Acetyl-Leu-Leu-norleucinal. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 13: 753-8. PMID 8787865 DOI: 10.1016/0736-5748(95)00060-7  0.92
1994 Sacher MG, Athlan ES, Mushynski WE. Increased phosphorylation of the amino-terminal domain of the low molecular weight neurofilament subunit in okadaic acid-treated neurons. The Journal of Biological Chemistry. 269: 18480-4. PMID 8034596  0.92
1992 Frederickson RM, Mushynski WE, Sonenberg N. Phosphorylation of translation initiation factor eIF-4E is induced in a ras-dependent manner during nerve growth factor-mediated PC12 cell differentiation. Molecular and Cellular Biology. 12: 1239-47. PMID 1545805  0.92
1992 Sacher MG, Athlan ES, Mushynski WE. Okadaic acid induces the rapid and reversible disruption of the neurofilament network in rat dorsal root ganglion neurons. Biochemical and Biophysical Research Communications. 186: 524-30. PMID 1321614 DOI: 10.1016/S0006-291X(05)80839-3  0.92
1990 Yanagihara T, Brengman JM, Mushynski WE. Differential vulnerability of microtubule components in cerebral ischemia. Acta Neuropathologica. 80: 499-505. PMID 2251907 DOI: 10.1007/BF00294610  0.92
1989 Georges E, Lindenbaum MH, Sacher MG, Trifaró JM, Mushynski WE. Neurofilament phosphorylation in cultured bovine adrenal chromaffin cells is stimulated by phorbol ester. Journal of Neurochemistry. 52: 1156-61. PMID 2926395  0.92
1988 Julien JP, Côté F, Beaudet L, Sidky M, Flavell D, Grosveld F, Mushynski W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit. Gene. 68: 307-14. PMID 3220257 DOI: 10.1016/0378-1119(88)90033-9  0.92
1988 Lefebvre S, Mushynski WE. Characterization of the cation-binding properties of porcine neurofilaments. Biochemistry. 27: 8503-8. PMID 3149507  0.92
1988 Lindenbaum MH, Carbonetto S, Grosveld F, Flavell D, Mushynski WE. Transcriptional and post-transcriptional effects of nerve growth factor on expression of the three neurofilament subunits in PC-12 cells. The Journal of Biological Chemistry. 263: 5662-7. PMID 3128545  0.92
1987 Lindenbaum MH, Carbonetto S, Mushynski WE. Nerve growth factor enhances the synthesis, phosphorylation, and metabolic stability of neurofilament proteins in PC12 cells. The Journal of Biological Chemistry. 262: 605-10. PMID 3804999  0.92
1987 Lefebvre S, Mushynski WE. Calcium binding to untreated and dephosphorylated porcine neurofilaments. Biochemical and Biophysical Research Communications. 145: 1006-11. PMID 3606591 DOI: 10.1016/0006-291X(87)91535-X  0.92
1987 Georges E, Mushynski WE. Chemical modification of charged amino acid moieties alters the electrophoretic mobilities of neurofilament subunits on SDS/polyacrylamide gels. European Journal of Biochemistry / Febs. 165: 281-7. PMID 3595591  0.92
1987 Georges E, Trifaró JM, Mushynski WE. Hypophosphorylated neurofilament subunits in the cytoskeletal and soluble fractions of cultured bovine adrenal chromaffin cells. Neuroscience. 22: 753-63. PMID 3118238 DOI: 10.1016/0306-4522(87)90370-8  0.92
1987 Hurst J, Flavell D, Julien JP, Meijer D, Mushynski W, Grosveld F. The human neurofilament gene (NEFL) is located on the short arm of chromosome 8. Cytogenetics and Cell Genetics. 45: 30-2. PMID 3036423 DOI: 10.1159/000132421  0.92
1987 Julien JP, Grosveld F, Yazdanbaksh K, Flavell D, Meijer D, Mushynski W. The structure of a human neurofilament gene (NF-L): a unique exon-intron organization in the intermediate filament gene family. Biochimica Et Biophysica Acta. 909: 10-20. PMID 3034332 DOI: 10.1016/0167-4781(87)90041-8  0.92
1986 Georges E, Lefebvre S, Mushynski WE. Dephosphorylation of neurofilaments by exogenous phosphatases has no effect on reassembly of subunits. Journal of Neurochemistry. 47: 477-83. PMID 3734790  0.92
1985 Kaspi C, Mushynski WE. Characterization of interspecies size heterogeneity of the large subunit of mammalian neurofilaments Annals of the New York Academy of Sciences. 794-796.  0.92
1984 Bader MF, Georges E, Mushynski WE, Trifaró JM. Neurofilament proteins in cultured chromaffin cells. Journal of Neurochemistry. 43: 1180-93. PMID 6432962  0.92
1984 Palo J, Haltia M, Carpenter S, Karpati G, Mushynski W. Neurofilament subunit-related proteins in neuronal intranuclear inclusions Annals of Neurology. 15: 322-328. PMID 6331276  0.92
1983 Julien JP, Smoluk GD, Mushynski WE. Characteristics of the protein kinase activity associated with rat neurofilament preparations. Biochimica Et Biophysica Acta. 755: 25-31. PMID 6681714 DOI: 10.1016/0304-4165(83)90268-4  0.92
1983 Julien JP, Mushynski WE. The distribution of phosphorylation sites among identified proteolytic fragments of mammalian neurofilaments. The Journal of Biological Chemistry. 258: 4019-25. PMID 6339492  0.92
1982 Julien JP, Mushynski WE. Multiple phosphorylation sites in mammalian neurofilament polypeptides. The Journal of Biological Chemistry. 257: 10467-70. PMID 7202005  0.92
1981 Julien JP, Mushynski WE. A comparison of in vitro- and in vivo-phosphorylated neurofilament polypeptides. Journal of Neurochemistry. 37: 1579-85. PMID 7199562  0.92
1981 Julien JP, Mushynski WE, Duncan ID, Griffiths IR. Giant axonal neuropathy: neurofilaments isolated from diseased dogs have a normal polypeptide composition. Experimental Neurology. 72: 619-27. PMID 7195344 DOI: 10.1016/0014-4886(81)90010-8  0.92
1979 Lee RW, Mushynski WE, Trifaró JM. Two forms of cytoplasmic actin in adrenal chromaffin cells. Neuroscience. 4: 843-52. PMID 481755 DOI: 10.1016/0306-4522(79)90013-7  0.92
1979 Thérien HM, Mushynski WE. Characterization of the cyclic 3',5'-nucleotide phosphodiesterase actitivty associated with synaptosomal plasma membranes and synaptic junctions. Biochimica Et Biophysica Acta. 585: 201-9. PMID 222347 DOI: 10.1016/0304-4165(79)90020-5  0.92
1979 Thérien HM, Mushynski WE. Distribution and properties of protein kinase and protein phosphatase activities in synaptosomal plasma membranes and synaptic junctions. Biochimica Et Biophysica Acta. 585: 188-200. PMID 222346 DOI: 10.1016/0304-4165(79)90019-9  0.92
1978 Mushynski WE, Glen S, Thérien HM. Actin-like and tubulin-like proteins in synaptic junctional complexes. Canadian Journal of Biochemistry. 56: 820-30. PMID 688068  0.92
1976 Therien HM, Mushynski WE. Isolation of synaptic junctional complexes of high structural integrity from rat brain. The Journal of Cell Biology. 71: 807-22. PMID 186464  0.92
1974 Metuzals J, Mushynski WE. Electron microscope and experimental investigations of the neurofilamentous network in Deiters' neurons. Relationship with the cell surface and nuclear pores. The Journal of Cell Biology. 61: 701-22. PMID 4599504  0.92
1973 Mushynski WE, Levitan IB, Ramirez G. Competition hybridization studies on brain ribonucleic acid from rats reared in enriched and deprived environments. Journal of Neurochemistry. 20: 309-17. PMID 4572743  0.92
1972 Ramirez G, Levitan IB, Mushynski WE. Amino acid incorporation into nerve ending structures in vitro. Febs Letters. 21: 17-20. PMID 11946464  0.92
1972 Levitan IB, Mushynski WE, Ramirez G. Effects of environmental complexity on amino acid incorporation into rat cortex and hippocampus in vivo. Journal of Neurochemistry. 19: 2621-30. PMID 5086248  0.92
1972 Ramirez G, Levitan IB, Mushynski WE. Highly purified synaptosomal membranes from rat brain. Incorporation of amino acids into membrane proteins in vitro. The Journal of Biological Chemistry. 247: 5382-90. PMID 5055773  0.92
1972 Ramirez G, Levitan IB, Mushynski WE. Double-isotope studies on brain protein synthesis with ( 3 H)- and ( 14 C)leucine: a warning. Brain Research. 43: 309-12. PMID 5050201 DOI: 10.1016/0006-8993(72)90303-4  0.92
1972 Levitan IB, Mushynski WE, Ramirez G. Effects of an enriched environment on amino acid incorporation into rat brain sub-cellular fractions in vivo. Brain Research. 41: 498-502. PMID 5038344 DOI: 10.1016/0006-8993(72)90524-0  0.92
1972 Levitan IB, Ramirez G, Mushynski WE. Amino acid incorporation in the brains of rats trained to use the non-preferred paw in retrieving food. Brain Research. 47: 147-56. PMID 4641264 DOI: 10.1016/0006-8993(72)90258-2  0.92
1972 Levitan IB, Mushynski WE, Ramirez G. Highly purified synaptosomal membranes from rat brain. Preparation and characterization. The Journal of Biological Chemistry. 247: 5376-81. PMID 4341344  0.92
1970 Mushynski WE, Spencer JH. Nucleotide clusters in deoxyribonucleic acids. V. The pyrimidine oligonucleotides of strands r and l of bacteriophage T7 DNA. Journal of Molecular Biology. 52: 91-106. PMID 5485911 DOI: 10.1016/0022-2836(70)90179-8  0.92
1970 Mushynski WE, Spencer JH. Nucleotide clusters in deoxyribonucleic acids. VI. The pyrimidine oligonucleotides of strands r and l of bacteriophage lambda DNA. Journal of Molecular Biology. 52: 107-20. PMID 5485908 DOI: 10.1016/0022-2836(70)90180-4  0.92
1969 Spencer JH, Cape RE, Marks A, Mushynski WE. Nucleotide clusters in deoxyribonucleic acids. II. Investigation of methods for isolation of pyrimidine oligonucleotides. Canadian Journal of Biochemistry. 47: 329-37. PMID 5778216  0.92
1968 Spencer JH, Cape RE, Marks A, Mushynski WE. Quantitative determination of pyrimidine nucleotide clusters by a single spectrophotometric measurement. Canadian Journal of Biochemistry. 46: 627-30. PMID 5660422  0.92
1968 Cerný R, Mushynski WE, Spencer JH. Nucleotide clusters in deoxyribonucleic acids. 3. Separation of pyrimidine isostichs according to base composition. Biochimica Et Biophysica Acta. 169: 439-50. PMID 4883325  0.92
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