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Takashi Daniel Yoshida Kozai, PhD - Publications

Bioengineering University of Pittsburgh, Pittsburgh, PA, United States 
Neural Engineering

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Eles JR, Stieger KC, Kozai TDY. The temporal pattern of Intracortical Microstimulation pulses elicits distinct temporal and spatial recruitment of cortical neuropil and neurons. Journal of Neural Engineering. PMID 33075762 DOI: 10.1088/1741-2552/abc29c  0.96
2020 Trevathan JK, Asp AJ, Nicolai EN, Trevathan J, Kremer NA, Kozai TDY, Cheng D, Schachter M, Nassi JJ, Otte SL, Parker JG, Lujan JL, Ludwig K. Calcium imaging in freely-moving mice during electrical stimulation of deep brain structures. Journal of Neural Engineering. PMID 32916665 DOI: 10.1088/1741-2552/abb7a4  0.6
2020 Stieger KC, Eles JR, Ludwig KA, Kozai TDY. In vivo microstimulation with cathodic and anodic asymmetric waveforms modulates spatiotemporal calcium dynamics in cortical neuropil and pyramidal neurons of male mice. Journal of Neuroscience Research. PMID 32592267 DOI: 10.1002/jnr.24676  0.96
2020 Yang Q, Wu B, Eles JR, Vazquez AL, Kozai TDY, Cui XT. Zwitterionic Polymer Coating Suppresses Microglial Encapsulation to Neural Implants In Vitro and In Vivo. Advanced Biosystems. e1900287. PMID 32363792 DOI: 10.1002/adbi.201900287  0.96
2020 Wellman SM, Guzman K, Stieger KC, Brink LE, Sridhar S, Dubaniewicz MT, Li L, Cambi F, Kozai TDY. Cuprizone-induced oligodendrocyte loss and demyelination impairs recording performance of chronically implanted neural interfaces. Biomaterials. 239: 119842. PMID 32065972 DOI: 10.1016/j.biomaterials.2020.119842  0.88
2020 Eles JR, Kozai TDY. In vivo imaging of calcium and glutamate responses to intracortical microstimulation reveals distinct temporal responses of the neuropil and somatic compartments in layer II/III neurons. Biomaterials. 234: 119767. PMID 31954232 DOI: 10.1016/j.biomaterials.2020.119767  0.96
2019 Ereifej ES, Shell C, Schofield JS, Charkhkar H, Cuberovic I, Dorval AC, Graczyk EL, Kozai TDY, Otto KJ, Tyler DJ, Welle CG, Widge AS, Zariffa J, Moritz C, Bourbeau D, et al. Neural engineering: the process, applications, and its role in the future of medicine. Journal of Neural Engineering. PMID 31557730 DOI: 10.1088/1741-2552/ab4869  0.8
2019 Kozai TDY, Purcell EK. Pipette-integrated microelectrodes. Nature Biomedical Engineering. 3: 682-683. PMID 31501567 DOI: 10.1038/s41551-019-0452-x  0.96
2019 Wellman SM, Li L, Yaxiaer Y, McNamara I, Kozai TDY. Revealing Spatial and Temporal Patterns of Cell Death, Glial Proliferation, and Blood-Brain Barrier Dysfunction Around Implanted Intracortical Neural Interfaces. Frontiers in Neuroscience. 13: 493. PMID 31191216 DOI: 10.3389/fnins.2019.00493  0.8
2019 Eles JR, Vazquez AL, Kozai TDY, Cui XT. Meningeal inflammatory response and fibrous tissue remodeling around intracortical implants: An in vivo two-photon imaging study. Biomaterials. 195: 111-123. PMID 30634095 DOI: 10.1016/j.biomaterials.2018.12.031  0.96
2019 Stocking KC, Vazquez AL, Kozai T. Intracortical neural stimulation with untethered, ultrasmall carbon fiber electrodes mediated by the photoelectric effect. Ieee Transactions On Bio-Medical Engineering. PMID 30605086 DOI: 10.1109/TBME.2018.2889832  0.96
2018 Salatino JW, Ludwig KA, Kozai TDY, Purcell EK. Publisher Correction: Glial responses to implanted electrodes in the brain. Nature Biomedical Engineering. 2: 52. PMID 31015653 DOI: 10.1038/s41551-017-0177-7  0.96
2018 Michelson NJ, Eles JR, Vazquez AL, Ludwig KA, Kozai TDY. Calcium activation of cortical neurons by continuous electrical stimulation: Frequency dependence, temporal fidelity, and activation density. Journal of Neuroscience Research. PMID 30585651 DOI: 10.1002/jnr.24370  0.96
2018 Baranov SV, Baranova OV, Yablonska S, Suofu Y, Vazquez AL, Kozai TDY, Cui XT, Ferrando LM, Larkin TM, Tyurina YY, Kagan VE, Carlisle DL, Kristal BS, Friedlander RM. Mitochondria modulate programmed neuritic retraction. Proceedings of the National Academy of Sciences of the United States of America. PMID 30584104 DOI: 10.1073/pnas.1811021116  0.96
2018 Nicolai EN, Michelson NJ, Settell ML, Hara SA, Trevathan JK, Asp AJ, Stocking KC, Lujan JL, Kozai TDY, Ludwig KA. Design Choices for Next-Generation Neurotechnology Can Impact Motion Artifact in Electrophysiological and Fast-Scan Cyclic Voltammetry Measurements. Micromachines. 9. PMID 30424427 DOI: 10.3390/mi9100494  0.96
2018 Kozai TDY. The History and Horizons of Microscale Neural Interfaces. Micromachines. 9. PMID 30424378 DOI: 10.3390/mi9090445  0.88
2018 Wellman SM, Cambi F, Kozai TD. The role of oligodendrocytes and their progenitors on neural interface technology: A novel perspective on tissue regeneration and repair. Biomaterials. 183: 200-217. PMID 30172245 DOI: 10.1016/j.biomaterials.2018.08.046  0.8
2018 Michelson NJ, Kozai TDY. Isoflurane and Ketamine Differentially Influence Spontaneous and Evoked Laminar Electrophysiology in Mouse V1. Journal of Neurophysiology. PMID 30067128 DOI: 10.1152/jn.00299.2018  0.96
2018 Golabchi A, Wu B, Li X, Carlisle DL, Kozai TDY, Friedlander RM, Cui XT. Melatonin improves quality and longevity of chronic neural recording. Biomaterials. 180: 225-239. PMID 30053658 DOI: 10.1016/j.biomaterials.2018.07.026  0.96
2018 Wellman SM, Eles JR, Ludwig KA, Seymour JP, Michelson NJ, McFadden WE, Vazquez AL, Kozai TDY. A Materials Roadmap to Functional Neural Interface Design. Advanced Functional Materials. 28. PMID 29805350 DOI: 10.1002/adfm.201701269  0.96
2018 Eles JR, Vazquez AL, Kozai TDY, Cui XT. In vivo imaging of neuronal calcium during electrode implantation: Spatial and temporal mapping of damage and recovery. Biomaterials. 174: 79-94. PMID 29783119 DOI: 10.1016/j.biomaterials.2018.04.043  0.96
2018 Wellman SM, Kozai TDY. In vivo spatiotemporal dynamics of NG2 glia activity caused by neural electrode implantation. Biomaterials. 164: 121-133. PMID 29501892 DOI: 10.1016/j.biomaterials.2018.02.037  0.8
2018 Cody PA, Eles JR, Lagenaur CF, Kozai TDY, Cui XT. Unique electrophysiological and impedance signatures between encapsulation types: An analysis of biological Utah array failure and benefit of a biomimetic coating in a rat model. Biomaterials. 161: 117-128. PMID 29421549 DOI: 10.1016/j.biomaterials.2018.01.025  0.96
2018 Iordanova B, Vazquez A, Kozai TD, Fukuda M, Kim SG. Optogenetic investigation of the variable neurovascular coupling along the interhemispheric circuits. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18755225. PMID 29372655 DOI: 10.1177/0271678X18755225  0.92
2017 Salatino JW, Ludwig KA, Kozai TDY, Purcell EK. Glial responses to implanted electrodes in the brain. Nature Biomedical Engineering. 1: 862-877. PMID 30505625 DOI: 10.1038/s41551-017-0154-1  0.96
2017 Michelson NJ, Vazquez AL, Eles JR, Salatino JW, Purcell EK, Williams JJ, Cui T, Kozai TDY. Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: New Emphasis on the Biological Interface. Journal of Neural Engineering. PMID 29182149 DOI: 10.1088/1741-2552/aa9dae  0.96
2017 Wellman SM, Kozai TDY. Understanding the Inflammatory Tissue Reaction to Brain Implants To Improve Neurochemical Sensing Performance. Acs Chemical Neuroscience. PMID 29120167 DOI: 10.1021/acschemneuro.7b00403  0.8
2016 Eles JR, Vazquez AL, Snyder NR, Lagenaur C, Murphy MC, Kozai TD, Cui XT. Neuroadhesive L1 coating attenuates acute microglial attachment to neural electrodes as revealed by live two-photon microscopy. Biomaterials. 113: 279-292. PMID 27837661 DOI: 10.1016/j.biomaterials.2016.10.054  0.96
2016 Khilwani R, Gilgunn PJ, Kozai TD, Ong XC, Korkmaz E, Gunalan PK, Cui XT, Fedder GK, Ozdoganlar OB. Ultra-miniature ultra-compliant neural probes with dissolvable delivery needles: design, fabrication and characterization. Biomedical Microdevices. 18: 97. PMID 27778225 DOI: 10.1007/s10544-016-0125-4  0.96
2016 Patel PR, Zhang H, Robbins MT, Nofar JB, Marshall SP, Kobylarek MJ, Kozai TD, Kotov NA, Chestek CA. Chronic in vivo stability assessment of carbon fiber microelectrode arrays. Journal of Neural Engineering. 13: 066002. PMID 27705958 DOI: 10.1088/1741-2560/13/6/066002  0.48
2016 Kozai TD, Jaquins-Gerstl AS, Vazquez AL, Michael AC, Cui XT. Dexamethasone retrodialysis attenuates microglial response to implanted probes in vivo. Biomaterials. 87: 157-169. PMID 26923363 DOI: 10.1016/j.biomaterials.2016.02.013  0.96
2015 Kozai TD, Eles JR, Vazquez AL, Cui XT. Two-photon imaging of chronically implanted neural electrodes: Sealing methods and new insights. Journal of Neuroscience Methods. PMID 26526459 DOI: 10.1016/j.jneumeth.2015.10.007  0.96
2015 Alba NA, Du ZJ, Catt KA, Kozai TD, Cui XT. In Vivo Electrochemical Analysis of a PEDOT/MWCNT Neural Electrode Coating. Biosensors. 5: 618-46. PMID 26473938 DOI: 10.3390/bios5040618  0.96
2015 Kozai TD, Vazquez AL. Photoelectric artefact from optogenetics and imaging on microelectrodes and bioelectronics: New Challenges and Opportunities. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 3: 4965-4978. PMID 26167283 DOI: 10.1039/C5TB00108K  0.96
2015 Kozai T, Catt K, Du Z, Kyounghwan N, Srivannavit O, Haque RU, Seymour J, Wise K, Yoon E, Cui X. Chronic in vivo evaluation of PEDOT/CNT for stable neural recordings. Ieee Transactions On Bio-Medical Engineering. PMID 26087481 DOI: 10.1109/TBME.2015.2445713  0.96
2015 Patel PR, Na K, Zhang H, Kozai TD, Kotov NA, Yoon E, Chestek CA. Insertion of linear 8.4 μm diameter 16 channel carbon fiber electrode arrays for single unit recordings. Journal of Neural Engineering. 12: 046009. PMID 26035638 DOI: 10.1088/1741-2560/12/4/046009  0.96
2015 Kolarcik CL, Luebben SD, Sapp SA, Hanner J, Snyder N, Kozai TD, Chang E, Nabity JA, Nabity ST, Lagenaur CF, Cui XT. Elastomeric and soft conducting microwires for implantable neural interfaces. Soft Matter. 11: 4847-61. PMID 25993261 DOI: 10.1039/c5sm00174a  0.96
2015 Kozai TD, Jaquins-Gerstl AS, Vazquez AL, Michael AC, Cui XT. Brain tissue responses to neural implants impact signal sensitivity and intervention strategies. Acs Chemical Neuroscience. 6: 48-67. PMID 25546652 DOI: 10.1021/cn500256e  0.96
2015 Kozai TD, Du Z, Gugel ZV, Smith MA, Chase SM, Bodily LM, Caparosa EM, Friedlander RM, Cui XT. Comprehensive chronic laminar single-unit, multi-unit, and local field potential recording performance with planar single shank electrode arrays. Journal of Neuroscience Methods. 242: 15-40. PMID 25542351 DOI: 10.1016/j.jneumeth.2014.12.010  0.96
2015 Kolarcik CL, Catt K, Rost E, Albrecht IN, Bourbeau D, Du Z, Kozai TD, Luo X, Weber DJ, Cui XT. Evaluation of poly(3,4-ethylenedioxythiophene)/carbon nanotube neural electrode coatings for stimulation in the dorsal root ganglion. Journal of Neural Engineering. 12: 016008. PMID 25485675 DOI: 10.1088/1741-2560/12/1/016008  0.96
2015 Kozai TD, Catt K, Li X, Gugel ZV, Olafsson VT, Vazquez AL, Cui XT. Mechanical failure modes of chronically implanted planar silicon-based neural probes for laminar recording. Biomaterials. 37: 25-39. PMID 25453935 DOI: 10.1016/j.biomaterials.2014.10.040  0.96
2014 Kozai TD, Li X, Bodily LM, Caparosa EM, Zenonos GA, Carlisle DL, Friedlander RM, Cui XT. Effects of caspase-1 knockout on chronic neural recording quality and longevity: insight into cellular and molecular mechanisms of the reactive tissue response. Biomaterials. 35: 9620-34. PMID 25176060 DOI: 10.1016/j.biomaterials.2014.08.006  0.96
2014 Kozai TD, Gugel Z, Li X, Gilgunn PJ, Khilwani R, Ozdoganlar OB, Fedder GK, Weber DJ, Cui XT. Chronic tissue response to carboxymethyl cellulose based dissolvable insertion needle for ultra-small neural probes. Biomaterials. 35: 9255-68. PMID 25128375 DOI: 10.1016/j.biomaterials.2014.07.039  0.96
2012 Kozai TD, Langhals NB, Patel PR, Deng X, Zhang H, Smith KL, Lahann J, Kotov NA, Kipke DR. Ultrasmall implantable composite microelectrodes with bioactive surfaces for chronic neural interfaces. Nature Materials. 11: 1065-73. PMID 23142839 DOI: 10.1038/nmat3468  0.96
2012 Kozai TD, Vazquez AL, Weaver CL, Kim SG, Cui XT. In vivo two-photon microscopy reveals immediate microglial reaction to implantation of microelectrode through extension of processes. Journal of Neural Engineering. 9: 066001. PMID 23075490 DOI: 10.1088/1741-2560/9/6/066001  0.96
2012 Gilgunn PJ, Khilwani R, Kozai TDY, Weber DJ, Cui XT, Erdos G, Ozdoganlar OB, Fedder GK. An ultra-compliant, scalable neural probe with molded biodissolvable delivery vehicle Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 56-59. DOI: 10.1109/MEMSYS.2012.6170092  0.96
2010 Kozai TD, Marzullo TC, Hooi F, Langhals NB, Majewska AK, Brown EB, Kipke DR. Reduction of neurovascular damage resulting from microelectrode insertion into the cerebral cortex using in vivo two-photon mapping. Journal of Neural Engineering. 7: 046011. PMID 20644246 DOI: 10.1088/1741-2560/7/4/046011  0.96
2009 Escamilla-Mackert T, Langhals NB, Kozai TD, Kipke DR. Insertion of a three dimensional silicon microelectrode assembly through a thick meningeal membrane. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 1616-8. PMID 19964007 DOI: 10.1109/IEMBS.2009.5333221  0.96
2009 Kozai TD, Kipke DR. Insertion shuttle with carboxyl terminated self-assembled monolayer coatings for implanting flexible polymer neural probes in the brain. Journal of Neuroscience Methods. 184: 199-205. PMID 19666051 DOI: 10.1016/j.jneumeth.2009.08.002  0.96
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