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Robert M. Friedlander, MD. MA - Publications

Cerebrovascular Neurosurgery  University of Pittsburgh, Pittsburgh, PA, United States 

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Baranov SV, Baranova OV, Yablonska S, Suofu Y, Vazquez AL, Kozai TDY, Cui XT, Ferrando LM, Larkin TM, Tyurina YY, Kagan VE, Carlisle DL, Kristal BS, Friedlander RM. Mitochondria modulate programmed neuritic retraction. Proceedings of the National Academy of Sciences of the United States of America. PMID 30584104 DOI: 10.1073/Pnas.1811021116  0.6
2018 Caparosa EM, Sedgewick AJ, Zenonos G, Zhao Y, Carlisle DL, Stefaneanu L, Jankowitz BT, Gardner P, Chang YF, Lariviere WR, LaFramboise WA, Benos PV, Friedlander RM. Regional Molecular Signature of the Symptomatic Atherosclerotic Carotid Plaque. Neurosurgery. PMID 30335165 DOI: 10.1093/Neuros/Nyy470  0.6
2018 Golabchi A, Wu B, Li X, Carlisle DL, Kozai TDY, Friedlander RM, Cui XT. Melatonin improves quality and longevity of chronic neural recording. Biomaterials. 180: 225-239. PMID 30053658 DOI: 10.1016/J.Biomaterials.2018.07.026  0.6
2015 Raji CA, Eyre H, Wei SH, Bredesen DE, Moylan S, Law M, Small G, Thompson PM, Friedlander RM, Silverman DH, Baune BT, Hoang TA, Salamon N, Toga AW, Vernooij MW. Hot Topics in Research: Preventive Neuroradiology in Brain Aging and Cognitive Decline. Ajnr. American Journal of Neuroradiology. PMID 26045577 DOI: 10.3174/Ajnr.A4409  0.6
2015 Sirianni AC, Jiang J, Zeng J, Mao LL, Zhou S, Sugarbaker P, Zhang X, Li W, Friedlander RM, Wang X. N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis. Journal of Neurochemistry. PMID 26031348 DOI: 10.1111/Jnc.13190  0.6
2015 Tempel ZJ, Friedlander RM, Monaco EA. A novel vehicle for the delivery of exogenous neurotrophic factors in spinal cord injury. Neurosurgery. 76: N11-3. PMID 25594196 DOI: 10.1227/01.Neu.0000460591.70933.9B  0.6
2015 Kagan VE, Tyurina YY, Tyurin VA, Mohammadyani D, Angeli JP, Baranov SV, Klein-Seetharaman J, Friedlander RM, Mallampalli RK, Conrad M, Bayir H. Cardiolipin signaling mechanisms: collapse of asymmetry and oxidation. Antioxidants & Redox Signaling. 22: 1667-80. PMID 25566681 DOI: 10.1089/Ars.2014.6219  0.6
2015 Kozai TD, Du Z, Gugel ZV, Smith MA, Chase SM, Bodily LM, Caparosa EM, Friedlander RM, Cui XT. Comprehensive chronic laminar single-unit, multi-unit, and local field potential recording performance with planar single shank electrode arrays. Journal of Neuroscience Methods. 242: 15-40. PMID 25542351 DOI: 10.1016/J.Jneumeth.2014.12.010  0.6
2015 Bulsara KR, Günel M, Amin-Hanjani S, Chen PR, Connolly ES, Friedlander RM. Results of a national cerebrovascular neurosurgery survey on the management of cerebral vasospasm/delayed cerebral ischemia. Journal of Neurointerventional Surgery. 7: 408-11. PMID 24811742 DOI: 10.1136/Neurintsurg-2014-011223  0.6
2015 Weiner GM, Grandhi R, Zwagerman NT, Agarwal N, Friedlander RM. Aneurysmal subarachnoid hemorrhage with concomitant posterior communicating artery fenestration. The International Journal of Neuroscience. 125: 154-8. PMID 24761761 DOI: 10.3109/00207454.2014.918119  0.6
2014 Zwagerman NT, Friedlander RM, Monaco EA. Intratumoral Clostridium novyi as a potential treatment for solid necrotic brain tumors. Neurosurgery. 75: N17-8. PMID 25406624 DOI: 10.1227/01.Neu.0000457197.94533.68  0.6
2014 Johnson S, Friedlander RM, Monaco EA. Complete spinal cord injury: an indication for spinal cord stimulation? Neurosurgery. 75: N23-4. PMID 25232793 DOI: 10.1227/01.Neu.0000454764.67990.Cb  0.6
2014 Weiner GM, Grandhi R, Friedlander RM. Conservative management vs intervention for unruptured brain arteriovenous malformations. Jama. 312: 1057-8. PMID 25203087 DOI: 10.1001/jama.2014.8748  0.6
2014 Kozai TD, Li X, Bodily LM, Caparosa EM, Zenonos GA, Carlisle DL, Friedlander RM, Cui XT. Effects of caspase-1 knockout on chronic neural recording quality and longevity: insight into cellular and molecular mechanisms of the reactive tissue response. Biomaterials. 35: 9620-34. PMID 25176060 DOI: 10.1016/J.Biomaterials.2014.08.006  0.6
2014 Abhinav K, Yeh FC, Pathak S, Suski V, Lacomis D, Friedlander RM, Fernandez-Miranda JC. Advanced diffusion MRI fiber tracking in neurosurgical and neurodegenerative disorders and neuroanatomical studies: A review. Biochimica Et Biophysica Acta. 1842: 2286-2297. PMID 25127851 DOI: 10.1016/J.Bbadis.2014.08.002  0.6
2014 Bambakidis NC, Cockroft KM, Hirsch JA, Connolly ES, Amin-Hanjani S, Meyers PM, Friedlander RM. The case against a randomized trial of unruptured brain arteriovenous malformations: misinterpretation of a flawed study. Stroke; a Journal of Cerebral Circulation. 45: 2808-10. PMID 25082809 DOI: 10.1161/Strokeaha.114.006519  0.6
2014 Monaco EA, Tempel ZJ, Friedlander RM. In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma. Neurosurgery. 75: N23-5. PMID 25033366 DOI: 10.1227/01.Neu.0000452321.37602.77  0.6
2014 Panczykowski DM, Monaco EA, Friedlander RM. Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans. Neurosurgery. 74: N8. PMID 24836106 DOI: 10.1227/Neu.0000000000000365  0.6
2014 Yano H, Baranov SV, Baranova OV, Kim J, Pan Y, Yablonska S, Carlisle DL, Ferrante RJ, Kim AH, Friedlander RM. Inhibition of mitochondrial protein import by mutant huntingtin. Nature Neuroscience. 17: 822-31. PMID 24836077 DOI: 10.1038/Nn.3721  0.6
2014 Abhinav K, Yeh FC, El-Dokla A, Ferrando LM, Chang YF, Lacomis D, Friedlander RM, Fernandez-Miranda JC. Use of diffusion spectrum imaging in preliminary longitudinal evaluation of amyotrophic lateral sclerosis: development of an imaging biomarker. Frontiers in Human Neuroscience. 8: 270. PMID 24808852 DOI: 10.3389/Fnhum.2014.00270  0.6
2014 Chivukula S, Grandhi R, Friedlander RM. A brief history of early neuroanesthesia. Neurosurgical Focus. 36: E2. PMID 24684332 DOI: 10.3171/2014.2.Focus13578  0.6
2014 Panczykowski DM, Monaco EA, Friedlander RM. Connectivity features for identifying cognitive impairment in presymptomatic carotid stenosis. Neurosurgery. 74: N9-N11. PMID 24642996 DOI: 10.1227/01.Neu.0000445332.48541.09  0.6
2014 Abhinav K, Pathak S, Richardson RM, Engh J, Gardner P, Yeh FC, Friedlander RM, Fernandez-Miranda JC. Application of high-definition fiber tractography in the management of supratentorial cavernous malformations: a combined qualitative and quantitative approach. Neurosurgery. 74: 668-80; discussion 6. PMID 24589561 DOI: 10.1227/Neu.0000000000000336  0.6
2014 Zhou H, Wang J, Jiang J, Stavrovskaya IG, Li M, Li W, Wu Q, Zhang X, Luo C, Zhou S, Sirianni AC, Sarkar S, Kristal BS, Friedlander RM, Wang X. N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2967-78. PMID 24553937 DOI: 10.1523/Jneurosci.1948-13.2014  0.6
2014 Monaco EA, Weiner GM, Friedlander RM. Scar in the injured spinal cord: the news is not all bad. Neurosurgery. 74: N15-6. PMID 24435146 DOI: 10.1227/01.Neu.0000442977.99453.A2  0.6
2014 Agarwalla PK, Walcott BP, Dunn IF, Thiex R, Frerichs K, Narang S, Friedlander RM. Fusiform aneurysms of the lenticulostriate artery. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 21: 373-7. PMID 24156904 DOI: 10.1016/j.jocn.2013.07.009  0.6
2013 Lee P, Monaco EA, Friedlander RM. Blocking TGF-β activity and associated inflammation may halt hydrocephalus. Neurosurgery. 73: N13-4. PMID 24257337 DOI: 10.1227/01.Neu.0000438332.72566.F5  0.6
2013 Modo M, Ambrosio F, Friedlander RM, Badylak SF, Wechsler LR. Bioengineering solutions for neural repair and recovery in stroke. Current Opinion in Neurology. 26: 626-31. PMID 24136127 DOI: 10.1097/Wco.0000000000000031  0.6
2013 Zenonos G, Monaco EA, Friedlander RM. A BigBrain for all…. Neurosurgery. 73: N16-7. PMID 24051714 DOI: 10.1227/01.Neu.0000435116.18521.48  0.6
2013 Tempel ZJ, Monaco EA, Friedlander RM. Pericytes as a therapeutic target in scar formation after spinal cord injury. Neurosurgery. 73: N18-20. PMID 23867272 DOI: 10.1227/01.Neu.0000432624.52020.86  0.6
2013 Bambakidis NC, Cockroft K, Connolly ES, Amin-Hanjani S, Morcos J, Meyers PM, Alexander MJ, Friedlander RM. Preliminary results of the ARUBA study. Neurosurgery. 73: E379-81. PMID 23867264 DOI: 10.1227/Neu.0000000000000067  0.6
2013 Pandya RS, Zhu H, Li W, Bowser R, Friedlander RM, Wang X. Therapeutic neuroprotective agents for amyotrophic lateral sclerosis. Cellular and Molecular Life Sciences : Cmls. 70: 4729-45. PMID 23864030 DOI: 10.1007/S00018-013-1415-0  0.6
2013 Epperly M, Berhane H, Cao S, Shields D, Franicola D, Goff JP, Zhang X, Wang H, Friedlander R, Greenberger JS. Increased longevity of hematopoiesis in continuous marrow cultures and radiation resistance of marrow stromal and hematopoietic progenitor cells from caspase-1 homozygous recombinant-negative (knockout) mice In Vivo. 27: 419-430. PMID 23812211  0.6
2013 Monaco EA, Tempel Z, Friedlander RM. Inflammation triggered by traumatic brain injury may continue to harm the brain for a lifetime. Neurosurgery. 72: N19-20. PMID 23685514 DOI: 10.1227/01.Neu.0000430738.63491.F3  0.6
2013 Zusman EE, Heary RF, Stroink AR, Berger MS, Popp AJ, Friedlander RM, Martin NA, Lonser RR, Asthagiri AR. Philanthropy funding for neurosurgery research and program development. Neurosurgery. 73: 177-83. PMID 23615103 DOI: 10.1227/01.Neu.0000429863.50018.F0  0.6
2013 Zhang Y, Cook A, Kim J, Baranov SV, Jiang J, Smith K, Cormier K, Bennett E, Browser RP, Day AL, Carlisle DL, Ferrante RJ, Wang X, Friedlander RM. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiology of Disease. 55: 26-35. PMID 23537713 DOI: 10.1016/J.Nbd.2013.03.008  0.6
2013 Monaco EA, Friedlander RM. Molecular targets for neonatal communicating hydrocephalus, putting shunts out to pasture? Neurosurgery. 72: N18-9. PMID 23511831 DOI: 10.1227/01.Neu.0000428423.76243.Df  0.6
2013 Monaco EA, Weiner GM, Friedlander RM. Randomized-controlled trial of minocycline for spinal cord injury shows promise. Neurosurgery. 72: N17-9. PMID 23328658 DOI: 10.1227/01.Neu.0000426215.12831.57  0.6
2013 Laaksamo E, Tulamo R, Liiman A, Baumann M, Friedlander RM, Hernesniemi J, Kangasniemi M, Niemelä M, Laakso A, Frösen J. Oxidative stress is associated with cell death, wall degradation, and increased risk of rupture of the intracranial aneurysm wall. Neurosurgery. 72: 109-17. PMID 23096423 DOI: 10.1227/Neu.0B013E3182770E8C  0.6
2013 Vaitkevicius H, Erdemli HE, Anderson WS, Zamani AA, Friedlander RM, Folkerth RD. Biopsy neuropathology of cerebral ischemia associated with a developmental venous anomaly. Clinical Neurology and Neurosurgery. 115: 621-3. PMID 22771305 DOI: 10.1016/J.Clineuro.2012.06.014  0.6
2012 Monaco EA, Friedlander RM. Harnessing the brain's tools for killing cancer cells could be a key to treating high-grade gliomas. Neurosurgery. 71: N23-4. PMID 23160399 DOI: 10.1227/01.Neu.0000423048.50677.07  0.6
2012 Tempel Z, Monaco EA, Friedlander RM. Recovery of cortical control over locomotion after spinal cord injury. Neurosurgery. 71: N19-20. PMID 22989970 DOI: 10.1227/01.Neu.0000419712.10158.62  0.6
2012 Monaco EA, Friedlander RM. Novel triple-modality molecular imaging approach holds promise for improving brain tumor resection. Neurosurgery. 71: N14-5. PMID 22811198 DOI: 10.1227/Neu.0B013E3181Ae7E0E  0.6
2012 Li M, Akhavan-Sharif RM, Friedlander RM, Du R, Thiex R. What sequences on high-field MR best depict temporal resolution of experimental ICH and edema formation in mice? Journal of Biomedicine & Biotechnology. 2012: 961461. PMID 22619500 DOI: 10.1155/2012/961461  0.6
2012 Monaco EA, Friedlander RM. Neuroprosthetic learning utilizes the same neural circuitry required for motor learning. Neurosurgery. 70: N10. PMID 22596002 DOI: 10.1227/01.Neu.0000414940.40978.6C  0.6
2012 Fernandez-Miranda JC, Pathak S, Engh J, Jarbo K, Verstynen T, Yeh FC, Wang Y, Mintz A, Boada F, Schneider W, Friedlander R. High-definition fiber tractography of the human brain: neuroanatomical validation and neurosurgical applications. Neurosurgery. 71: 430-53. PMID 22513841 DOI: 10.1227/Neu.0B013E3182592Faa  0.6
2012 Monaco EA, Friedlander RM. A novel target for ischemic stroke therapy: pannexins. Neurosurgery. 70: N13-4. PMID 22426053 DOI: 10.1227/01.Neu.0000413220.21264.Df  0.6
2012 Lin N, Zenonos G, Kim AH, Nalbach SV, Du R, Frerichs KU, Friedlander RM, Gormley WB. Angiogram-negative subarachnoid hemorrhage: relationship between bleeding pattern and clinical outcome. Neurocritical Care. 16: 389-98. PMID 22350856 DOI: 10.1007/S12028-012-9680-6  0.6
2012 Laaksamo E, Ramachandran M, Frösen J, Tulamo R, Baumann M, Friedlander RM, Harbaugh RE, Hernesniemi J, Niemelä M, Raghavan ML, Laakso A. Intracellular signaling pathways and size, shape, and rupture history of human intracranial aneurysms. Neurosurgery. 70: 1565-72; discussion . PMID 22278358 DOI: 10.1227/Neu.0B013E31824C057E  0.6
2012 Monaco EA, Friedlander RM. Neuronal transplants reconstitute complex neuronal circuitry and rescue phenotype. Neurosurgery. 70: N11-2. PMID 22251979 DOI: 10.1227/01.Neu.0000410931.31205.D2  0.6
2012 Lin N, Cahill KS, Frerichs KU, Friedlander RM, Claus EB. Treatment of ruptured and unruptured cerebral aneurysms in the USA: a paradigm shift. Journal of Neurointerventional Surgery. 4: 182-9. PMID 21990481 DOI: 10.1136/Jnis.2011.004978  0.6
2012 Zenonos G, Lin N, Kim A, Kim JE, Governale L, Friedlander RM. Carotid endarterectomy with primary closure: analysis of outcomes and review of the literature. Neurosurgery. 70: 646-54; discussion 6. PMID 21904262 DOI: 10.1227/Neu.0B013E3182351De0  0.6
2011 Zhang Y, Friedlander RM. Using non-coding small RNAs to develop therapies for Huntington's disease. Gene Therapy. 18: 1139-49. PMID 22158031 DOI: 10.1038/gt.2011.170  0.6
2011 Tomycz ND, Richardson RM, Friedlander RM. Seizures and free radicals: the antioxidant may become the next anticonvulsant. Neurosurgery. 69: N12-3. PMID 22067342 DOI: 10.1227/01.Neu.0000407917.06492.A8  0.6
2011 Wang X, Sirianni A, Pei Z, Cormier K, Smith K, Jiang J, Zhou S, Wang H, Zhao R, Yano H, Kim JE, Li W, Kristal BS, Ferrante RJ, Friedlander RM. The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14496-507. PMID 21994366 DOI: 10.1523/Jneurosci.3059-11.2011  0.6
2011 Tomycz ND, Friedlander RM. The experience of pain and the putamen: a new link found with functional MRI and diffusion tensor imaging. Neurosurgery. 69: N12-3. PMID 21900799 DOI: 10.1227/01.Neu.0000405590.47966.E8  0.6
2011 Tomycz ND, Friedlander RM. Memory training unlocks brain plasticity in prodromal Alzheimer's disease. Neurosurgery. 69: N13-4. PMID 21792126 DOI: 10.1227/01.Neu.0000400013.85906.95  0.6
2011 Tomycz ND, Friedlander RM. α-1 Adrenergic receptor signaling linked to memory dysfunction following brain trauma. Neurosurgery. 68: N16-8. PMID 21792097 DOI: 10.1227/01.Neu.0000395791.89648.93  0.6
2011 Tomycz ND, Friedlander RM. Battling brain diabetes: antioxidants may reduce cognitive deficits induced by cholesterol. Neurosurgery. 68: N15-7. PMID 21778942 DOI: 10.1227/01.Neu.0000398207.79197.5D  0.6
2011 Lin N, Dunn IF, Glantz M, Allison DL, Jensen R, Johnson MD, Friedlander RM, Kesari S. Benefit of ventriculoperitoneal cerebrospinal fluid shunting and intrathecal chemotherapy in neoplastic meningitis: a retrospective, case-controlled study. Journal of Neurosurgery. 115: 730-6. PMID 21721878 DOI: 10.3171/2011.5.Jns101768  0.6
2011 Tomycz ND, Friedlander RM. Neuromodulation of the locus coeruleus: a key to controlling wakefulness. Neurosurgery. 68: N14-5. PMID 21654567 DOI: 10.1227/01.Neu.0000393589.31014.61  0.6
2011 Zhang Y, Wang X, Baranov SV, Zhu S, Huang Z, Fellows-Mayle W, Jiang J, Day AL, Kristal BS, Friedlander RM. Dipyrone inhibits neuronal cell death and diminishes hypoxic/ischemic brain injury. Neurosurgery. 69: 942-56. PMID 21552169 DOI: 10.1227/Neu.0B013E318222Afb2  0.6
2011 Wong JM, Governale LS, Friedlander RM. Use of a simple internal fiducial as an adjunct to enhance intraoperative ultrasound-assisted guidance: technical note. Neurosurgery. 69: ons34-9; discussion . PMID 21346649 DOI: 10.1227/Neu.0B013E3182124851  0.6
2011 Tharin SA, Klein AM, Friedlander RM. Arteriovenous malformations The Causes of Epilepsy: Common and Uncommon Causes in Adults and Children. 551-558. DOI: 10.1017/CBO9780511921001.080  0.6
2010 Zenonos G, Friedlander RM. Diffusion weighted imaging: what are we really seeing? Neurosurgery. 67: N26-9. PMID 21107175 DOI: 10.1227/01.Neu.0000390621.96326.28  0.6
2010 Tomycz ND, Friedlander RM. Electrical stimulation of the thalamus modulates cortico-cortical signaling. Neurosurgery. 67: N23-4. PMID 21107173 DOI: 10.1227/01.Neu.0000390619.11574.D2  0.6
2010 Friedlander RM. Stenting versus endarterectomy for carotid-artery stenosis. The New England Journal of Medicine. 363: 1766; author reply 1. PMID 20979480 DOI: 10.1056/Nejmc1009626  0.6
2010 Tomycz ND, Friedlander RM. Novel neurogenesis drugs uncovered from in vivo chemical library screen. Neurosurgery. 67: N16-8. PMID 20881540 DOI: 10.1227/01.Neu.0000389733.03740.D3  0.6
2010 Lin N, Li M, Friedlander RM. Embolus extravasation: a new mechanism for microvascular recanalization? Neurosurgery. 67: N22-3. PMID 20644408 DOI: 10.1227/01.Neu.0000386970.79323.Cd  0.6
2010 Shankar GM, Chen L, Kim AH, Ross GL, Folkerth RD, Friedlander RM. Composite ganglioneuroma-paraganglioma of the filum terminale. Journal of Neurosurgery. Spine. 12: 709-13. PMID 20515359 DOI: 10.3171/2009.12.Spine09482  0.6
2010 Lin N, Li M, Friedlander RM. Noninvasive monitoring of neural activity with bioluminescence. Neurosurgery. 66: N16-7. PMID 20495413 DOI: 10.1227/01.Neu.0000375276.61284.50  0.6
2010 Lin N, Friedlander RM. Regeneration of neuromuscular synapses: action of microRNA-206. Neurosurgery. 66: N19-20. PMID 20305481 DOI: 10.1227/01.Neu.0000369898.34291.27  0.6
2010 Yanamadala V, Friedlander RM. Complement in neuroprotection and neurodegeneration. Trends in Molecular Medicine. 16: 69-76. PMID 20116331 DOI: 10.1016/J.Molmed.2009.12.001  0.6
2010 Pouladi MA, Xie Y, Skotte NH, Ehrnhoefer DE, Graham RK, Kim JE, Bissada N, Yang XW, Paganetti P, Friedlander RM, Leavitt BR, Hayden MR. Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression. Human Molecular Genetics. 19: 1528-38. PMID 20097678 DOI: 10.1093/Hmg/Ddq026  0.6
2010 Lin N, Friedlander RM. Real-time multiphoton microscopy in moving animals: new frontier of functional imaging. Neurosurgery. 66: N12-3. PMID 20087117 DOI: 10.1227/01.Neu.0000367838.37023.B2  0.6
2009 Lin N, Friedlander RM. T-cell activation in ischemic stroke: a new therapeutic target for delayed infarct expansion? Neurosurgery. 65: N13. PMID 19934952 DOI: 10.1227/01.Neu.0000345343.04287.23  0.6
2009 Mislow JM, Friedlander RM. Targeted oncogenes create a new realistic mouse model of glioblastoma multiforme. Neurosurgery. 64: N13. PMID 19404135 DOI: 10.1227/01.Neu.0000351426.75827.7B  0.6
2009 Wang X, Figueroa BE, Stavrovskaya IG, Zhang Y, Sirianni AC, Zhu S, Day AL, Kristal BS, Friedlander RM. Methazolamide and melatonin inhibit mitochondrial cytochrome C release and are neuroprotective in experimental models of ischemic injury. Stroke; a Journal of Cerebral Circulation. 40: 1877-85. PMID 19299628 DOI: 10.1161/Strokeaha.108.540765  0.6
2009 Graham RK, Pouladi MA, Joshi P, Lu G, Deng Y, Wu NP, Figueroa BE, Metzler M, André VM, Slow EJ, Raymond L, Friedlander R, Levine MS, Leavitt BR, Hayden MR. Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2193-204. PMID 19228972 DOI: 10.1523/Jneurosci.5473-08.2009  0.6
2009 Zhang Y, Engelman J, Friedlander RM. Allele-specific silencing of mutant Huntington's disease gene. Journal of Neurochemistry. 108: 82-90. PMID 19094060 DOI: 10.1111/J.1471-4159.2008.05734.X  0.6
2009 Mislow JMK, Friedlander RM. Hope on the horizon for traumatic brain injury from an unlikely partner: Alzheimer's disease Neurosurgery. 65: N13-N14. DOI: 10.1227/01.Neu.0000357602.35809.1B  0.6
2009 Chen L, Tanriover G, Yano H, Friedlander R, Louvi A, Gunel M. Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation 3 Stroke. 40: 1474-1481. DOI: 10.1161/STROKEAHA.108.527135  0.6
2008 Komotar RJ, Syed ON, Bruce JN, Connolly ES, Dunn IF, Friedlander RM. Genomics of human glioblastoma multiforme: a glimpse of the future. Neurosurgery. 63: 15. PMID 19057310 DOI: 10.1227/01.Neu.0000342663.21125.02  0.6
2008 Mislow JM, Friedlander RM. Neuromotor prosthetics: brain-computer interfaces, a step closer to benefitting paralyzed patients. Neurosurgery. 63: N8-9. PMID 18981872 DOI: 10.1227/01.Neu.0000339451.71215.3E  0.6
2008 Wang X, Zhu S, Pei Z, Drozda M, Stavrovskaya IG, Del Signore SJ, Cormier K, Shimony EM, Wang H, Ferrante RJ, Kristal BS, Friedlander RM. Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9473-85. PMID 18799679 DOI: 10.1523/Jneurosci.1867-08.2008  0.6
2008 Zhang WH, Wang H, Wang X, Narayanan MV, Stavrovskaya IG, Kristal BS, Friedlander RM. Nortriptyline protects mitochondria and reduces cerebral ischemia/hypoxia injury. Stroke; a Journal of Cerebral Circulation. 39: 455-62. PMID 18174477 DOI: 10.1161/Strokeaha.107.496810  0.6
2008 Dunn IF, Friedlander RM. Comments Neurosurgery. 63: 254-255. DOI: 10.1227/01.NEU.0000320439.27895.24  0.6
2008 Dunn IF, Friedlander RM. Letting T cells in: A boost for anti-tumor therapy? Neurosurgery. 62: N6. DOI: 10.1227/01.Neu.0000318150.42816.87  0.6
2008 Howard BM, Boockvar J, Dunn IF, Friedlander RM. Pluripotential stem cells from mature human somatic cells Neurosurgery. 62: N6-N7. DOI: 10.1227/01.Neu.0000315988.35152.A9  0.6
2008 Kim AH, Friedlander RM. Myocardial contrast echocardiography in subarachnoid hemorrhage-induced cardiac dysfunction: Case report - Commentary Neurosurgery. 62: E262. DOI: 10.1227/01.NEU.0000311088.26885.1D  0.6
2007 Krishnamurthy S, Kelleher JP, Lehman EB, Cockroft KM. Effects of tobacco dose and length of exposure on delayed neurological deterioration and overall clinical outcome after aneurysmal subarachnoid hemorrhage. Neurosurgery. 61: 475-80; discussion 4. PMID 17881958 DOI: 10.1227/01.NEU.0000290892.46954.12  0.6
2007 Bhattacharyya N, Friedlander RM. Images in clinical medicine. Pneumocephalus associated with pneumosinus dilatans frontalis. The New England Journal of Medicine. 357: 1136. PMID 17855674 DOI: 10.1056/Nejmicm062822  0.6
2007 Joffe HV, Parks MH, Meyer RJ, Jenkins JK, Temple R. Rosiglitazone and the FDA. The New England Journal of Medicine. 357: 1775-6; author reply. PMID 17761586 DOI: 10.1056/NEJMc076347  0.6
2007 Wang H, Guan Y, Wang X, Smith K, Cormier K, Zhu S, Stavrovskaya IG, Huo C, Ferrante RJ, Kristal BS, Friedlander RM. Nortriptyline delays disease onset in models of chronic neurodegeneration. The European Journal of Neuroscience. 26: 633-41. PMID 17686041 DOI: 10.1111/J.1460-9568.2007.05663.X  0.6
2007 Friedlander RM. Clinical practice. Arteriovenous malformations of the brain. The New England Journal of Medicine. 356: 2704-12. PMID 17596605 DOI: 10.1056/Nejmcp067192  0.6
2007 Guan YJ, Wang X, Wang HY, Kawagishi K, Ryu H, Huo CF, Shimony EM, Kristal BS, Kuhn HG, Friedlander RM. Increased stem cell proliferation in the spinal cord of adult amyotrophic lateral sclerosis transgenic mice. Journal of Neurochemistry. 102: 1125-38. PMID 17472707 DOI: 10.1111/J.1471-4159.2007.04610.X  0.6
2007 Governale LS, Friedlander RM. Investigation of radiofrequency-induced temperature elevation of aneurysm clips in a 3.0-tesla magnetic resonance environment: Commentary Neurosurgery. 61: 1066. DOI: 10.1227/01.neu.0000303202.69747.d2  0.6
2007 Dunn IF, Friedlander RM. A survey to determine the understanding of the conceptual basis and diagnostic tests used for brain death by neurosurgeons in Canada: Commentary Neurosurgery. 61: 1046-1047. DOI: 10.1227/  0.6
2007 Du R, Friedlander RM. Wall shear stress gradient analysis within an idealized stenosis using non-newtonian flow: Commentary Neurosurgery. 61: 864. DOI: 10.1227/01.NEU.0000298915.32248.95  0.6
2007 Kim AH, Friedlander RM. Arteriovenous transit time as a measure for microvascular perfusion in cerebral ischemia and reperfusion: Commentary Neurosurgery. 61: 833-834. DOI: 10.1227/01.NEU.0000298912.86506.B1  0.6
2006 Zhang Y, Leavitt BR, van Raamsdonk JM, Dragatsis I, Goldowitz D, MacDonald ME, Hayden MR, Friedlander RM. Huntingtin inhibits caspase-3 activation. The Embo Journal. 25: 5896-906. PMID 17124493 DOI: 10.1038/Sj.Emboj.7601445  0.6
2006 Dhib-Jalbut S, Arnold DL, Cleveland DW, Fisher M, Friedlander RM, Mouradian MM, Przedborski S, Trapp BD, Wyss-Coray T, Yong VW. Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. Journal of Neuroimmunology. 176: 198-215. PMID 16983747 DOI: 10.1016/J.Jneuroim.2006.03.027  0.6
2006 Wang X, Narayanan M, Bruey JM, Rigamonti D, Cattaneo E, Reed JC, Friedlander RM. Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death. Biochimica Et Biophysica Acta. 1762: 742-54. PMID 16920334 DOI: 10.1016/J.Bbadis.2006.06.015  0.6
2006 Stack EC, Smith KM, Ryu H, Cormier K, Chen M, Hagerty SW, Del Signore SJ, Cudkowicz ME, Friedlander RM, Ferrante RJ. Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice. Biochimica Et Biophysica Acta. 1762: 373-80. PMID 16364609 DOI: 10.1016/J.Bbadis.2005.11.002  0.6
2006 Friedlander RM, Dunn IF. Administration of ex vivo-expanded bone marrow-derived endothelial progenitor cells attenuates focal cerebral ischemia-reperfusion injury in rats: Commentary Neurosurgery. 59: 686. DOI: 10.1227/01.NEU.0000229058.08706.88  0.6
2006 Awad IA, Connolly ES, Kirsch M, Schackert G, Dunn IF, Friedlander RM. Proliferative activity through extracellular signal-regulated kinase of smooth muscle cells in vascular walls of cerebral arteriovenous malformations: Commentary Neurosurgery. 58: 747-748.  0.6
2005 Kuhn HG, Biebl M, Wilhelm D, Li M, Friedlander RM, Winkler J. Increased generation of granule cells in adult Bcl-2-overexpressing mice: a role for cell death during continued hippocampal neurogenesis. The European Journal of Neuroscience. 22: 1907-15. PMID 16262630 DOI: 10.1111/J.1460-9568.2005.04377.X  0.6
2005 Chen P, Dunn IF, Aglio LS, Day AL, Frerichs KU, Friedlander RM. Intraoperative awakening for vision examination during ophthalmic artery aneurysm clipping: technical case report. Neurosurgery. 56: E440; discussion E44. PMID 15794844 DOI: 10.1227/01.Neu.0000156846.61123.79  0.6
2005 Dunn IF, Friedlander RM. OASIS: Are CNS cell-specific survival mechanisms just a mirage? Neurosurgery. 56: N8. DOI: 10.1227/01.Neu.0000308740.55505.36  0.6
2005 Macdonald RL, Patel AB, Bederson JB, Stieg PA, Dunn IF, Friedlander RM. Lower incidence of symptomatic vasospasm after subarachnoid hemorrhage owing to ruptured vertebrobasilar aneurysms: Commentry Neurosurgery. 57: 1115-1116.  0.6
2005 Kuo JS, Friedlander RM, Komotar RJ, Connolly ES, Dhang S. Human recombinant factor VII for emergency reversal of coagulopathy in neurosurgical patients: A retrospective comparative study. Comments Neurosurgery. 57: 835-836.  0.6
2005 Awad IA, Komotar RJ, Connolly ES, Lawton MT, Dempsey R, Ellegala DB, Friedlander RM. A new model of reversible sinus sagittalis superior thrombosis in the rat: Magnetic resonance imaging changes. Comments Neurosurgery. 57: 579-580.  0.6
2005 Niemelä M, Lehecka M, Hernesniemi J, Ellegala DB, Friedlander RM. A novel minimally occlusive microvascular anastomosis technique using a temporary intraluminal shunt: A prospective technique to minimize brain ischemia time during superficial temporal artery-to-middle cerebral artery bypass. Comments Neurosurgery. 57: ONS-197-ONS-198.  0.6
2005 Friedlander RM, Kirsch M, Schackert G, Nozaki K, Hashimoto N. Testing the angiogenic potential of cerebrovascular malformations by use of a rat cornea model: Usefulness and novel assessment of changes over time: Comments Neurosurgery. 56: 1345-1346.  0.6
2005 Awad IA, Yaşargil MG, Abdulrauf SI, Friedlander RM, Hanel RA, Hopkins LN. Microsurgical anatomy of the dural arteries: Comments Neurosurgery. 56: ONS-250-ONS-251.  0.6
2005 Schackert G, Friedlander RM, Vates GE, Connolly ES, Rutka JT. Variations in structural protein expression and endothelial cell proliferation in relation to clinical manifestations of cerebral cavernous malformations: Comments Neurosurgery. 56: 353-354.  0.6
2005 Solomon RA, Friedlander RM, Do HM, Steinberg GK. Computed tomographic perfusion in the management of aneurysmal subarachnoid hemorrhage: New application of an existent technique: Comments Neurosurgery. 56: 316-317.  0.6
2005 Figueroa BE, Friedlander RM, Macdonald RL, Kelly M, Findlay JM, Mehra A, Connolly ES. Ideal suture diameter is critical for consistent middle cerebral artery occlusion in mice: Comments Neurosurgery. 56: ONS-199-ONS-200.  0.6
2004 Narayanan MV, Zhang W, Stavrovskaya IG, Kristal BS, Friedlander RM. Promethazine: a novel application as a neuroprotectant that reduces ischemia-mediated injury by inhibiting mitochondrial dysfunction. Clinical Neurosurgery. 51: 102-7. PMID 15571133  0.6
2004 Kristal BS, Stavrovskaya IG, Narayanan MV, Krasnikov BF, Brown AM, Beal MF, Friedlander RM. The mitochondrial permeability transition as a target for neuroprotection. Journal of Bioenergetics and Biomembranes. 36: 309-12. PMID 15377863 DOI: 10.1023/B:Jobb.0000041759.35731.70  0.6
2004 Stavrovskaya IG, Narayanan MV, Zhang W, Krasnikov BF, Heemskerk J, Young SS, Blass JP, Brown AM, Beal MF, Friedlander RM, Kristal BS. Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology. The Journal of Experimental Medicine. 200: 211-22. PMID 15263028 DOI: 10.1084/Jem.20032053  0.6
2004 Zhu S, Li M, Figueroa BE, Liu A, Stavrovskaya IG, Pasinelli P, Beal MF, Brown RH, Kristal BS, Ferrante RJ, Friedlander RM. Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5909-12. PMID 15229238 DOI: 10.1523/Jneurosci.1278-04.2004  0.6
2004 McGirt MJ, Blessing R, Nimjee SM, Friedman AH, Alexander MJ, Laskowitz DT, Lynch JR, Connolly ES, Macdonald RL, Hodge CJ, Narayanan M, Friedlander RM. Correlation of serum brain natriuretic peptide with hyponatremia and delayed ischemic neurological deficits after subarachnoid hemorrhage Neurosurgery. 54: 1369-1374. PMID 15157293  0.6
2004 Teng YD, Choi H, Onario RC, Zhu S, Desilets FC, Lan S, Woodard EJ, Snyder EY, Eichler ME, Friedlander RM. Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury. Proceedings of the National Academy of Sciences of the United States of America. 101: 3071-6. PMID 14981254 DOI: 10.1073/Pnas.0306239101  0.6
2004 Friedlander RM, Macdonald RL, Dumont AS, Kassell NF, Findlay JM. Delayed intracranial delivery of a nitric oxide donor from a controlled-release polymer prevents experimental cerebral vasospasm in rabbits: Comments Neurosurgery. 55: 1399-1400.  0.6
2003 Hersch S, Fink K, Vonsattel JP, Friedlander RM. Minocycline is protective in a mouse model of Huntington's disease. Annals of Neurology. 54: 841; author reply 84. PMID 14681897 DOI: 10.1002/Ana.21891  0.6
2003 Zhang WH, Wang X, Narayanan M, Zhang Y, Huo C, Reed JC, Friedlander RM. Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death. Proceedings of the National Academy of Sciences of the United States of America. 100: 16012-7. PMID 14663141 DOI: 10.1073/Pnas.2534856100  0.6
2003 Zhang Y, Ona VO, Li M, Drozda M, Dubois-Dauphin M, Przedborski S, Ferrante RJ, Friedlander RM. Sequential activation of individual caspases, and of alterations in Bcl-2 proapoptotic signals in a mouse model of Huntington's disease. Journal of Neurochemistry. 87: 1184-92. PMID 14622098 DOI: 10.1046/J.1471-4159.2003.02105.X  0.6
2003 Hai J, Li ST, Lin Q, Pan QG, Gao F, Ding MX, Findlay JM, Schackert G, Thomas JE, Lawton MT, Friedlander RM, Erkmen K. Vascular endothelial growth factor expression and angiogenesis induced by chronic cerebral hypoperfusion in rat brain Neurosurgery. 53: 963-972. PMID 14519228  0.6
2003 Zhang Y, Li M, Drozda M, Chen M, Ren S, Mejia Sanchez RO, Leavitt BR, Cattaneo E, Ferrante RJ, Hayden MR, Friedlander RM. Depletion of wild-type huntingtin in mouse models of neurologic diseases. Journal of Neurochemistry. 87: 101-6. PMID 12969257 DOI: 10.1046/J.1471-4159.2003.01980.X  0.6
2003 Mundia M, Edelstein PH, Friedlander RM, Slotkin JR. Case 16-2003 - Brain abscess [4] (multiple letters) New England Journal of Medicine. 349: 1004-1006. PMID 12959104 DOI: 10.1056/NEJM200309043491019  0.6
2003 Wang X, Zhu S, Drozda M, Zhang W, Stavrovskaya IG, Cattaneo E, Ferrante RJ, Kristal BS, Friedlander RM. Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 10483-7. PMID 12930891 DOI: 10.1073/Pnas.1832501100  0.6
2003 Kuzeyli K, Çakir E, Dinç H, Sayin OC, Friedlander RM, Soni D, Kopitnik TA, Loftus CM, Riina HA, Stieg PE. Midaortic syndrome and subarachnoid hemorrhage associated with ruptured middle cerebral artery aneurysm: Case report and review of the literature Neurosurgery. 52: 1460-1464. PMID 12762892  0.6
2003 Friedlander RM, Gonzalez RG, Afridi NA, Pfannl R. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 16-2003. A 58-year-old woman with left-sided weakness and a right frontal brain mass. The New England Journal of Medicine. 348: 2125-32. PMID 12761369 DOI: 10.1056/Nejmcpc030011  0.6
2003 Qureshi AI, Suri MFK, Ziai WC, Yahia AM, Mohammad Y, Sen S, Agarwal P, Zaidat OO, Suarez JI, Wityk RJ, Wijman CAC, Steinberg GK, Frerichs KU, Friedlander RM, Rosenwasser RH. Stroke-free survival and its determinants in patients with symptomatic vertebrobasilar stenosis: A multicenter study Neurosurgery. 52: 1033-1040. PMID 12699544  0.6
2003 Friedlander RM. Apoptosis and caspases in neurodegenerative diseases. The New England Journal of Medicine. 348: 1365-75. PMID 12672865 DOI: 10.1056/Nejmra022366  0.6
2003 Caird J, Burke M, Roberts G, Brett F, Phillips J, Usher D, Bouchier-Hayes D, Farrell M. Apolipoprotein(A) expression in intracranial aneurysms. Neurosurgery. 52: 854-8; discussion 85. PMID 12657181  0.6
2003 Zhang W, Narayanan M, Friedlander RM. Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS. Annals of Neurology. 53: 267-70. PMID 12557297 DOI: 10.1002/Ana.10476  0.6
2002 McGirt MJ, Lynch JR, Blessing R, Warner DS, Friedman AH, Laskowitz DT, Lawton MT, Awad IA, Max Findlay J, Friedlander RM. Serum von Willebrand factor, matrix metalloproteinase-9, and vascular endothelial growth factor levels predict the onset of cerebral vasospasm after aneurysmal subarachnoid hemorrhage Neurosurgery. 51: 1128-1135. PMID 12383357 DOI: 10.1097/00006123-200211000-00005  0.6
2002 Guégan C, Vila M, Teismann P, Chen C, Onténiente B, Li M, Friedlander RM, Przedborski S, Teissman P. Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS. Molecular and Cellular Neurosciences. 20: 553-62. PMID 12213439 DOI: 10.1006/Mcne.2002.1136  0.6
2002 Kiechle T, Dedeoglu A, Kubilus J, Kowall NW, Beal MF, Friedlander RM, Hersch SM, Ferrante RJ. Cytochrome C and caspase-9 expression in Huntington's disease. Neuromolecular Medicine. 1: 183-95. PMID 12095160 DOI: 10.1385/Nmm:1:3:183  0.6
2002 Garden GA, Budd SL, Tsai E, Hanson L, Kaul M, D'Emilia DM, Friedlander RM, Yuan J, Masliah E, Lipton SA. Caspase cascades in human immunodeficiency virus-associated neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4015-24. PMID 12019321 DOI: 10.1523/Jneurosci.22-10-04015.2002  0.6
2002 Zhu S, Stavrovskaya IG, Drozda M, Kim BY, Ona V, Li M, Sarang S, Liu AS, Hartley DM, Wu DC, Gullans S, Ferrante RJ, Przedborski S, Kristal BS, Friedlander RM. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature. 417: 74-8. PMID 11986668 DOI: 10.1038/417074A  0.6
2002 Wheeler VC, Gutekunst CA, Vrbanac V, Lebel LA, Schilling G, Hersch S, Friedlander RM, Gusella JF, Vonsattel JP, Borchelt DR, MacDonald ME. Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice. Human Molecular Genetics. 11: 633-40. PMID 11912178 DOI: 10.1093/Hmg/11.6.633  0.6
2001 Sanchez Mejia RO, Friedlander RM. Caspases in Huntington's disease. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 7: 480-9. PMID 11765125 DOI: 10.1177/107385840100700604  0.6
2001 Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, MacDonald ME, Friedlander RM, Silani V, Hayden MR, Timmusk T, Sipione S, Cattaneo E. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science (New York, N.Y.). 293: 493-8. PMID 11408619 DOI: 10.1126/Science.1059581  0.6
2001 Sanchez Mejia RO, Ona VO, Li M, Friedlander RM. Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction. Neurosurgery. 48: 1393-9; discussion 1. PMID 11383749 DOI: 10.1097/00006123-200106000-00051  0.6
2000 Fankhauser C, Friedlander RM, Gagliardini V. Prevention of nuclear localization of activated caspases correlates with inhibition of apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 5: 117-32. PMID 11232240 DOI: 10.1023/A:1009672411058  0.6
2000 Stieg PE, Friedlander RM, Loeffler JS, Alexander E. Arteriovenous malformations: indications for stereotactic radiosurgery. Clinical Neurosurgery. 47: 242-8. PMID 11197705  0.6
2000 Friedlander RM. Role of caspase 1 in neurologic disease. Archives of Neurology. 57: 1273-6. PMID 10987893 DOI: 10.1001/Archneur.57.9.1273  0.6
2000 Frerichs KU, Stieg PE, Friedlander RM. Prediction of aneurysm rupture site by an angiographically identified bleb at the aneurysm neck. Journal of Neurosurgery. 93: 517. PMID 10969960 DOI: 10.3171/Jns.2000.93.3.0517  0.6
2000 Li M, Ona VO, Chen M, Kaul M, Tenneti L, Zhang X, Stieg PE, Lipton SA, Friedlander RM. Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury. Neuroscience. 99: 333-42. PMID 10938439 DOI: 10.1016/S0306-4522(00)00173-1  0.6
2000 Andreassen OA, Ferrante RJ, Hughes DB, Klivenyi P, Dedeoglu A, Ona VO, Friedlander RM, Beal MF. Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant. Journal of Neurochemistry. 75: 847-52. PMID 10899963 DOI: 10.1046/J.1471-4159.2000.0750847.X  0.6
2000 Chen M, Ona VO, Li M, Ferrante RJ, Fink KB, Zhu S, Bian J, Guo L, Farrell LA, Hersch SM, Hobbs W, Vonsattel JP, Cha JH, Friedlander RM. Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nature Medicine. 6: 797-801. PMID 10888929 DOI: 10.1038/77528  0.6
2000 Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH. Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature. 405: 360-4. PMID 10830966 DOI: 10.1038/35012636  0.6
2000 Li M, Ona VO, Guégan C, Chen M, Jackson-Lewis V, Andrews LJ, Olszewski AJ, Stieg PE, Lee JP, Przedborski S, Friedlander RM. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science (New York, N.Y.). 288: 335-9. PMID 10764647 DOI: 10.1126/Science.288.5464.335  0.6
2000 Quiñones-Hinojosa A, Friedlander RM, Boyer PJ, Batchelor TT, Chiocca EA. Solitary sciatic nerve lymphoma as an initial manifestation of diffuse neurolymphomatosis. Case report and review of the literature. Journal of Neurosurgery. 92: 165-9. PMID 10616097 DOI: 10.3171/Jns.2000.92.1.0165  0.6
1999 Fink KB, Andrews LJ, Butler WE, Ona VO, Li M, Bogdanov M, Endres M, Khan SQ, Namura S, Stieg PE, Beal MF, Moskowitz MA, Yuan J, Friedlander RM. Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade. Neuroscience. 94: 1213-8. PMID 10625061 DOI: 10.1016/S0306-4522(99)00345-0  0.6
1999 Farber A, Connors JP, Friedlander RM, Wagner RJ, Powell RJ, Cronenwett JL. A specific inhibitor of apoptosis decreases tissue injury after intestinal ischemia-reperfusion in mice. Journal of Vascular Surgery. 30: 752-60. PMID 10514215 DOI: 10.1016/S0741-5214(99)70115-1  0.6
1999 Friedlander RM, Ojemann RG, Thornton AF. Management of meningiomas of the cavernous sinus: conservative surgery and adjuvant therapy. Clinical Neurosurgery. 45: 279-82. PMID 10461528  0.6
1999 Ona VO, Li M, Vonsattel JP, Andrews LJ, Khan SQ, Chung WM, Frey AS, Menon AS, Li XJ, Stieg PE, Yuan J, Penney JB, Young AB, Cha JH, Friedlander RM. Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature. 399: 263-7. PMID 10353249 DOI: 10.1038/20446  0.6
1999 Klevenyi P, Andreassen O, Ferrante RJ, Schleicher JR, Friedlander RM, Beal MF. Transgenic mice expressing a dominant negative mutant interleukin-1beta converting enzyme show resistance to MPTP neurotoxicity. Neuroreport. 10: 635-8. PMID 10208603 DOI: 10.1097/00001756-199902250-00035  0.6
1998 Friedlander RM, Yuan J. ICE, neuronal apoptosis and neurodegeneration. Cell Death and Differentiation. 5: 823-31. PMID 10203693 DOI: 10.1038/Sj.Cdd.4400433  0.6
1997 Teknos TN, Joseph MP, Megerian CA, Friedlander RM, Weber AL. Carotid artery hemorrhage resulting from temporal bone fracture. American Journal of Otolaryngology. 18: 338-40. PMID 9282252 DOI: 10.1016/S0196-0709(97)90030-2  0.6
1997 Cudkowicz ME, Warren L, Francis JW, Lloyd KJ, Friedlander RM, Borges LF, Kassem N, Munsat TL, Brown RH. Intrathecal administration of recombinant human superoxide dismutase 1 in amyotrophic lateral sclerosis: a preliminary safety and pharmacokinetic study. Neurology. 49: 213-22. PMID 9222193 DOI: 10.1212/Wnl.49.1.213  0.6
1997 Friedlander RM, Brown RH, Gagliardini V, Wang J, Yuan J. Inhibition of ICE slows ALS in mice. Nature. 388: 31. PMID 9214497 DOI: 10.1038/40299  0.6
1997 Hara H, Fink K, Endres M, Friedlander RM, Gagliardini V, Yuan J, Moskowitz MA. Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 370-5. PMID 9143219 DOI: 10.1097/00004647-199704000-00002  0.6
1997 Friedlander RM, Gagliardini V, Hara H, Fink KB, Li W, MacDonald G, Fishman MC, Greenberg AH, Moskowitz MA, Yuan J. Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. The Journal of Experimental Medicine. 185: 933-40. PMID 9120399 DOI: 10.1084/Jem.185.5.933  0.6
1993 Takamiya Y, Friedlander RM, Brem H, Malick A, Martuza RL. Inhibition of angiogenesis and growth of human nerve-sheath tumors by AGM-1470. Journal of Neurosurgery. 78: 470-6. PMID 8433151 DOI: 10.3171/Jns.1993.78.3.0470  0.6
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