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Robert M. Friedlander, MD. MA - Related publications

Affiliations: 
Cerebrovascular Neurosurgery  University of Pittsburgh, Pittsburgh, PA, United States 
Website:
http://www.neurosurgery.pitt.edu/research/neuroapoptosis/index.html
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Wei L, Fan Y, Wei L, He X, Yang J, Zheng X. Ablation of TMEM126B protects against oxygen-glucose deprivation/reoxygenation-induced injuries of PC12 cells via maintaining mitochondrial anti-apoptotic functions. Archives of Biochemistry and Biophysics. 108634. PMID 33075301 DOI: 10.1016/j.abb.2020.108634   
2020 Gu M, Mei XL, Zhao YN. Sepsis and Cerebral Dysfunction: BBB Damage, Neuroinflammation, Oxidative Stress, Apoptosis and Autophagy as Key Mediators and the Potential Therapeutic Approaches. Neurotoxicity Research. PMID 32876918 DOI: 10.1007/s12640-020-00270-5   
2020 Kim YH, Eom JW, Koh JY. Mechanism of Zinc Excitotoxicity: A Focus on AMPK. Frontiers in Neuroscience. 14: 577958. PMID 33041769 DOI: 10.3389/fnins.2020.577958   
2020 Liu X, Chu W, Shang S, Ma L, Jiang C, Ding Y, Wang J, Zhang S, Shao B. Preliminary study on the anti-apoptotic mechanism of Astragaloside IV on radiation-induced brain cells. International Journal of Immunopathology and Pharmacology. 34: 2058738420954594. PMID 32902354 DOI: 10.1177/2058738420954594   
2020 Wang XX, Zhang B, Xia R, Jia QY. Inflammation, apoptosis and autophagy as critical players in vascular dementia. European Review For Medical and Pharmacological Sciences. 24: 9601-9614. PMID 33015803 DOI: 10.26355/eurrev_202009_23048   
2020 Yang Y, Meng L, Wu S, Li Y, Zhong Y, Xu F, Zhou XC, Li GQ, Xu GL, Peng KF. LIGHT deficiency aggravates cisplatin-induced acute kidney injury by upregulating mitochondrial apoptosis. International Immunopharmacology. 89: 106999. PMID 33045563 DOI: 10.1016/j.intimp.2020.106999   
2020 Dojo Soeandy C, Elia AJ, Cao Y, Rodgers C, Huang S, Elia AC, Henderson JT. Necroptotic-Apoptotic Regulation in an Endothelin-1 Model of Cerebral Ischemia. Cellular and Molecular Neurobiology. PMID 32844322 DOI: 10.1007/s10571-020-00942-y   
2020 Gella A, Prada-Dacasa P, Carrascal M, Urpi A, González-Torres M, Abian J, Sanz E, Quintana A. Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome. Frontiers in Cell and Developmental Biology. 8: 660. PMID 32850799 DOI: 10.3389/fcell.2020.00660   
2020 Zou YH, Guan PP, Zhang SQ, Guo YS, Wang P. Rofecoxib Attenuates the Pathogenesis of Amyotrophic Lateral Sclerosis by Alleviating Cyclooxygenase-2-Mediated Mechanisms. Frontiers in Neuroscience. 14: 817. PMID 32903591 DOI: 10.3389/fnins.2020.00817   
2020 Aliena-Valero A, Rius-Pérez S, Baixauli-Martín J, Torregrosa G, Chamorro Á, Pérez S, Salom JB. Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke. Molecular Neurobiology. PMID 32959172 DOI: 10.1007/s12035-020-02115-w   
2020 Zheng D, Cao T, Zhang LL, Fan GC, Qiu J, Peng TQ. Targeted inhibition of calpain in mitochondria alleviates oxidative stress-induced myocardial injury. Acta Pharmacologica Sinica. PMID 32968209 DOI: 10.1038/s41401-020-00526-y   
2020 Zheng D, Cao T, Zhang LL, Fan GC, Qiu J, Peng TQ. Targeted inhibition of calpain in mitochondria alleviates oxidative stress-induced myocardial injury. Acta Pharmacologica Sinica. PMID 32968209 DOI: 10.1038/s41401-020-00526-y   
2020 Saito LB, Fernandes JP, Smith MJ, Doan MAL, Branton WG, Schmitt LM, Wuest M, Monaco MC, Major EO, Wuest F, Power C. Intranasal anti-caspase-1 therapy preserves myelin and glucose metabolism in a model of progressive multiple sclerosis. Glia. PMID 32882086 DOI: 10.1002/glia.23896   
2020 Gilon C, Gitlin-Domagalska A, Lahiani A, Yehoshua-Alshanski S, Shumacher-Klinger A, Gilon D, Taha M, Sekler I, Hoffman A, Lazarovici P. Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults. Peptides. 170399. PMID 32889021 DOI: 10.1016/j.peptides.2020.170399   
2020 Shi Y, Greven J, Guo W, Luo P, Xu D, Wang W, Relja B, Vollrath JT, Buhl EM, Horst K, Bolierakis E, Bläsius F, Hildebrand F. Trauma-Hemorrhage Stimulates Immune Defense, Mitochondrial Dysfunction, Autophagy and Apoptosis in Pig Liver at 72 H. Shock (Augusta, Ga.). PMID 32826806 DOI: 10.1097/SHK.0000000000001556   
2020 Natarajan V, Mah T, Peishi C, Tan SY, Chawla R, Arumugam TV, Ramasamy A, Mallilankaraman K. Oxygen Glucose Deprivation Induced Prosurvival Autophagy Is Insufficient to Rescue Endothelial Function. Frontiers in Physiology. 11: 533683. PMID 33041854 DOI: 10.3389/fphys.2020.533683   
2020 Kandezi N, Mohammadi M, Ghaffari M, Gholami M, Motaghinejad M, Safari S. Novel Insight to Neuroprotective Potential of Curcumin: A Mechanistic Review of Possible Involvement of Mitochondrial Biogenesis and PI3/Akt/ GSK3 or PI3/Akt/CREB/BDNF Signaling Pathways. International Journal of Molecular and Cellular Medicine. 9: 1-32. PMID 32832482 DOI: 10.22088/IJMCM.BUMS.9.1.1   
2020 Wang Z, Wang L, Wang J, Luo J, Ruan H, Zhang J. Purified Sika deer antler protein attenuates GM-induced nephrotoxicity by activating Nrf2 pathway and inhibiting NF-κB pathway. Scientific Reports. 10: 15601. PMID 32973191 DOI: 10.1038/s41598-020-71943-6   
2020 Xu MX, Dai XL, Kuang Q, Zhu LC, Hu LF, Lou DS, Li Q, Feng J, Wu YK, Ge CX, Wang BC, Tan J. Dysfunctional Rhbdf2 of proopiomelanocortin mitigates ambient particulate matter exposure-induced neurological injury and neuron loss by antagonizing oxidative stress and inflammatory reaction. Journal of Hazardous Materials. 400: 123158. PMID 32947736 DOI: 10.1016/j.jhazmat.2020.123158   
2020 Chen J, Bian X, Li Y, Xiao X, Yin Y, Du X, Wang C, Li L, Bai Y, Liu X. Moderate hypothermia induces protection against hypoxia/reoxygenation injury by enhancing SUMOylation in cardiomyocytes. Molecular Medicine Reports. PMID 32945433 DOI: 10.3892/mmr.2020.11374   
2020 Ma Z, Li K, Chen P, Pan J, Li X, Zhao G. Propofol Attenuates Inflammatory Damage via Inhibiting NLRP1-Casp1-Casp6 Signaling in Ischemic Brain Injury. Biological & Pharmaceutical Bulletin. 43: 1481-1489. PMID 32999158 DOI: 10.1248/bpb.b20-00050   
2020 Yu P, Ma S, Dai X, Cao F. Elabela alleviates myocardial ischemia reperfusion-induced apoptosis, fibrosis and mitochondrial dysfunction through PI3K/AKT signaling. American Journal of Translational Research. 12: 4467-4477. PMID 32913520   
2020 Selvaraj B, Tran Tu Nguyen U, Huh G, Hung Nguyen D, Mok IK, Lee H, Kang K, Nim Bae A, Won Kim D, Wook Lee J. Synthesis and Biological Evaluation of Chalcone Derivatives as Neuroprotective Agents against Glutamate-Induced HT22 Mouse Hippocampal Neuronal Cell Death. Bioorganic & Medicinal Chemistry Letters. 127597. PMID 33022369 DOI: 10.1016/j.bmcl.2020.127597   
2020 Afridi R, Lee WH, Suk K. Microglia Gone Awry: Linking Immunometabolism to Neurodegeneration. Frontiers in Cellular Neuroscience. 14: 246. PMID 32903682 DOI: 10.3389/fncel.2020.00246   
2020 Miller HC, Louw R, Mereis M, Venter G, Boshoff JD, Mienie L, van Reenen M, Venter M, Lindeque JZ, Domínguez-Martínez A, Quintana A, van der Westhuizen FH. Metallothionein 1 Overexpression Does Not Protect Against Mitochondrial Disease Pathology in Ndufs4 Knockout Mice. Molecular Neurobiology. PMID 32918239 DOI: 10.1007/s12035-020-02121-y   
2020 Subramani J, Kundumani-Sridharan V, Das KC. Thioredoxin protects mitochondrial structure, function and biogenesis in myocardial ischemia-reperfusion via redox-dependent activation of AKT-CREB- PGC1α pathway in aged mice. Aging. 12: 19809-19827. PMID 33049718 DOI: 10.18632/aging.104071   
2020 Liu L, Fang R, Wei Z, Wu J, Li X, Li W. Induces Apoptosis in Intestinal Epithelial Cells via Reactive Oxygen Species-Mediated Mitochondrial Pathway In Vitro. Pathogens (Basel, Switzerland). 9. PMID 32842537 DOI: 10.3390/pathogens9090693   
2020 He Q, Liu H, Deng S, Chen X, Li D, Jiang X, Zeng W, Lu W. The Golgi Apparatus May Be a Potential Therapeutic Target for Apoptosis-Related Neurological Diseases. Frontiers in Cell and Developmental Biology. 8: 830. PMID 33015040 DOI: 10.3389/fcell.2020.00830   
2020 Yu H, Song L, Cao X, Li W, Zhao Y, Chen J, Li J, Chen Y, Yu W, Xu Y. Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling. Frontiers in Pharmacology. 11: 1173. PMID 32848779 DOI: 10.3389/fphar.2020.01173   
2020 Yang X, Sun J, Sun F, Yao Y, Tian T, Zhou J, Shen W, Lu M, Lei M. TRIM31 promotes apoptosis via TAK1-mediated activation of NF-κB signaling in sepsis-induced myocardial dysfunction. Cell Cycle (Georgetown, Tex.). 1-16. PMID 33016203 DOI: 10.1080/15384101.2020.1826235   
2020 Wang P, Zhang N, Wu B, Wu S, Zhang Y, Sun Y. The Role of Mitochondria in Vascular Calcification. Journal of Translational Internal Medicine. 8: 80-90. PMID 32983930 DOI: 10.2478/jtim-2020-0013   
2020 Ruera CN, Miculán E, Pérez F, Ducca G, Carasi P, Chirdo FG. Sterile inflammation drives multiple programmed cell death pathways in the gut. Journal of Leukocyte Biology. PMID 32946645 DOI: 10.1002/JLB.3MA0820-660R   
2020 Kim J, Joshi HP, Sheen SH, Kim KT, Kyung JW, Choi H, Kim YW, Kwon SY, Roh EJ, Choi UY, Sohn S, Kim YH, Park CK, Kumar H, Han IB. Resolvin D3 Promotes Inflammatory Resolution, Neuroprotection, and Functional Recovery After Spinal Cord Injury. Molecular Neurobiology. PMID 32964315 DOI: 10.1007/s12035-020-02118-7   
2020 Cui Y, Pan M, Ma J, Song X, Cao W, Zhang P. Recent progress in the use of mitochondrial membrane permeability transition pore in mitochondrial dysfunction-related disease therapies. Molecular and Cellular Biochemistry. PMID 33000352 DOI: 10.1007/s11010-020-03926-0   
2020 Yang C, Yang Y, DeMars KM, Rosenberg GA, Candelario-Jalil E. Genetic Deletion or Pharmacological Inhibition of Cyclooxygenase-2 Reduces Blood-Brain Barrier Damage in Experimental Ischemic Stroke. Frontiers in Neurology. 11: 887. PMID 32973660 DOI: 10.3389/fneur.2020.00887   
2020 Gebril SM, Ito Y, Shibata MA, Maemura K, Abu-Dief EE, Hussein MRA, Abdelaal UM, Elsayed HM, Otsuki Y, Higuchi K. Indomethacin can induce cell death in rat gastric parietal cells through alteration of some apoptosis- and autophagy-associated molecules. International Journal of Experimental Pathology. PMID 32985762 DOI: 10.1111/iep.12370   
2020 Mao XW, Nishiyama NC, Byrum SD, Stanbouly S, Jones T, Holley J, Sridharan V, Boerma M, Tackett AJ, Willey JS, Pecaut MJ, Delp MD. Spaceflight induces oxidative damage to blood-brain barrier integrity in a mouse model. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32981077 DOI: 10.1096/fj.202001754R   
2020 Duan C, Wang L, Zhang J, Xiang X, Wu Y, Zhang Z, Li Q, Tian K, Xue M, Liu L, Li T. Mdivi-1 attenuates oxidative stress and exerts vascular protection in ischemic/hypoxic injury by a mechanism independent of Drp1 GTPase activity. Redox Biology. 37: 101706. PMID 32911435 DOI: 10.1016/j.redox.2020.101706   
2020 Warpsinski G, Smith MJ, Srivastava S, Keeley TP, Siow RCM, Fraser PA, Mann GE. Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation. Redox Biology. 37: 101708. PMID 32949969 DOI: 10.1016/j.redox.2020.101708   
2020 Wang C, Nie G, Zhuang Y, Hu R, Wu H, Xing C, Li G, Hu G, Yang F, Zhang C. Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells. Ecotoxicology and Environmental Safety. 205: 111188. PMID 32836151 DOI: 10.1016/j.ecoenv.2020.111188   
2020 Lu M, Guo J, Wu B, Zhou Y, Wu M, Farzaneh M, Khoshnam SE. Mesenchymal Stem Cell-Mediated Mitochondrial Transfer: a Therapeutic Approach for Ischemic Stroke. Translational Stroke Research. PMID 32975692 DOI: 10.1007/s12975-020-00853-6   
2020 Zhang S, Cao M, Fang F. The Role of Epigallocatechin-3-Gallate in Autophagy and Endoplasmic Reticulum Stress (ERS)-Induced Apoptosis of Human Diseases. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 26: e924558. PMID 32952149 DOI: 10.12659/MSM.924558   
2020 Zhou X, Liu J, Yang S, Su Y, Meng Z, Hu Y. Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells. Clinics (Sao Paulo, Brazil). 75: e1865. PMID 32935825 DOI: 10.6061/clinics/2020/e1865   
2020 He R, Jiang Y, Shi Y, Liang J, Zhao L. Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis. Materials Science & Engineering. C, Materials For Biological Applications. 117: 111314. PMID 32919674 DOI: 10.1016/j.msec.2020.111314   
2020 Rong R, Xia X, Peng H, Li H, You M, Liang Z, Yao F, Yao X, Xiong K, Huang J, Zhou R, Ji D. Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy. Cell Death & Disease. 11: 720. PMID 32883957 DOI: 10.1038/s41419-020-02922-y   
2020 Lian WW, Zhou W, Zhang BY, Jia H, Xu LJ, Liu AL, Du GH. DL0410 ameliorates cognitive disorder in SAMP8 mice by promoting mitochondrial dynamics and the NMDAR-CREB-BDNF pathway. Acta Pharmacologica Sinica. PMID 32868905 DOI: 10.1038/s41401-020-00506-2   
2020 Zhu Z, Cao D, Xu L, Song C, Wang Y, Li M, Yan J, Xie Z. Effect of Orexin-A on Mitochondrial Biogenesis, Mitophagy and Structure in HEK293-APPSWE Cell Model of Alzheimer's Disease. Clinical and Experimental Pharmacology & Physiology. PMID 33080054 DOI: 10.1111/1440-1681.13424   
2020 Rai Y, Anita, Kumari N, Singh S, Kalra N, Soni R, Bhatt AN. Mild mitochondrial uncoupling protects from ionizing radiation induced cell death by attenuating oxidative stress and mitochondrial damage. Biochimica Et Biophysica Acta. Bioenergetics. 148325. PMID 33065098 DOI: 10.1016/j.bbabio.2020.148325   
2020 Wang Y, Cui X, Lin Q, Cai J, Tang L, Liang Y. The active peptide KF-8 from rice bran attenuates oxidative stress in a mouse model of aging induced by D-galactose. Journal of Agricultural and Food Chemistry. PMID 32942847 DOI: 10.1021/acs.jafc.0c04358   
2020 Wang Y, Cui X, Lin Q, Cai J, Tang L, Liang Y. The active peptide KF-8 from rice bran attenuates oxidative stress in a mouse model of aging induced by D-galactose. Journal of Agricultural and Food Chemistry. PMID 32942847 DOI: 10.1021/acs.jafc.0c04358