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Joost Verhaagen, Ph.D. - Publications

Affiliations: 
Netherlands Institute for Neuroscience, Amsterdam-Zuidoost, Noord-Holland, Netherlands 
Website:
https://nin.nl/about-us/the-organisation/team/joost-verhaagen/
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Year Citation  Score
2022 Zhou L, Kong G, Palmisano I, Cencioni MT, Danzi M, De Virgiliis F, Chadwick JS, Crawford G, Yu Z, De Winter F, Lemmon V, Bixby J, Puttagunta R, Verhaagen J, Pospori C, et al. Reversible CD8 T cell-neuron cross-talk causes aging-dependent neuronal regenerative decline. Science (New York, N.Y.). 376: eabd5926. PMID 35549409 DOI: 10.1126/science.abd5926  0.318
2021 Mason MRJ, Erp S, Wolzak K, Behrens A, Raivich G, Verhaagen J. The Jun-dependent axon regeneration gene program: Jun promotes regeneration over plasticity. Human Molecular Genetics. PMID 34718572 DOI: 10.1093/hmg/ddab315  0.775
2021 van Vliet AC, Lee J, van der Poel M, Mason MRJ, Noordermeer JN, Fradkin LG, Tannemaat MR, Malessy MJA, Verhaagen J, De Winter F. Coordinated changes in the expression of Wnt pathway genes following human and rat peripheral nerve injury. Plos One. 16: e0249748. PMID 33848304 DOI: 10.1371/journal.pone.0249748  0.327
2020 Warren PM, Andrews MR, Smith M, Bartus K, Bradbury EJ, Verhaagen J, Fawcett JW, Kwok JCF. Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries. Scientific Reports. 10: 11262. PMID 32647242 DOI: 10.1038/S41598-020-67526-0  0.377
2020 Nieuwenhuis B, Haenzi B, Hilton S, Carnicer-Lombarte A, Hobo B, Verhaagen J, Fawcett JW. Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters. Gene Therapy. PMID 32576975 DOI: 10.1038/S41434-020-0169-1  0.425
2020 Eggers R, de Winter F, Smit L, Luimens M, Muir EM, Bradbury EJ, Tannemaat MR, Verhaagen J. Combining timed GDNF and ChABC gene therapy to promote long-distance regeneration following ventral root avulsion and repair. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32543730 DOI: 10.1096/Fj.202000559R  0.428
2020 Godinho MJ, Staal JL, Krishnan VS, Hodgetts SI, Pollett MA, Goodman DP, Teh L, Verhaagen J, Plant GW, Harvey AR. Regeneration of adult rat sensory and motor neuron axons through chimeric peroneal nerve grafts containing donor Schwann cells engineered to express different neurotrophic factors. Experimental Neurology. 113355. PMID 32422148 DOI: 10.1016/J.Expneurol.2020.113355  0.455
2020 Willems J, de Jong APH, Scheefhals N, Mertens E, Catsburg LAE, Poorthuis RB, de Winter F, Verhaagen J, Meye FJ, MacGillavry HD. ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons. Plos Biology. 18: e3000665. PMID 32275651 DOI: 10.1371/Journal.Pbio.3000665  0.349
2020 Carulli D, Broersen R, de Winter F, Muir EM, Mešković M, de Waal M, de Vries S, Boele HJ, Canto CB, De Zeeuw CI, Verhaagen J. Cerebellar plasticity and associative memories are controlled by perineuronal nets. Proceedings of the National Academy of Sciences of the United States of America. PMID 32152108 DOI: 10.1073/Pnas.1916163117  0.323
2019 Uyaniker S, van der Spek SJF, Reinders NR, Xiong H, Li KW, Bossers K, Smit AB, Verhaagen J, Kessels HW. The Effects of Sindbis Viral Vectors on Neuronal Function. Frontiers in Cellular Neuroscience. 13: 362. PMID 31440143 DOI: 10.3389/Fncel.2019.00362  0.383
2019 Eggers R, de Winter F, Arkenaar C, Tannemaat MR, Verhaagen J. Enhanced regeneration and reinnervation following timed GDNF gene therapy in a cervical ventral root avulsion. Experimental Neurology. 321: 113037. PMID 31425689 DOI: 10.1016/J.Expneurol.2019.113037  0.438
2019 Melief J, Orre M, Bossers K, van Eden CG, Schuurman KG, Mason MRJ, Verhaagen J, Hamann J, Huitinga I. Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis. Acta Neuropathologica Communications. 7: 60. PMID 31023360 DOI: 10.1186/S40478-019-0705-7  0.307
2019 Boggio EM, Ehlert EM, Lupori L, Moloney EB, De Winter F, Vander Kooi CW, Baroncelli L, Mecollari V, Blits B, Fawcett JW, Verhaagen J, Pizzorusso T. Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex. Molecular Neurobiology. PMID 30706367 DOI: 10.1007/S12035-019-1499-0  0.307
2019 Eggers R, de Winter F, Hoyng SA, Hoeben RC, Malessy MJA, Tannemaat MR, Verhaagen J. Timed GDNF gene therapy using an immune-evasive gene switch promotes long distance axon regeneration. Brain : a Journal of Neurology. PMID 30649249 DOI: 10.1093/Brain/Awy340  0.465
2018 Hu YT, Chen XL, Huang SH, Zhu QB, Yu SY, Shen Y, Sluiter A, Verhaagen J, Zhao J, Swaab D, Bao AM. Early growth response-1 regulates acetylcholinesterase and its relation with the course of Alzheimer's disease. Brain Pathology (Zurich, Switzerland). PMID 30511454 DOI: 10.1111/Bpa.12688  0.447
2018 Fawcett JW, Verhaagen J. Intrinsic Determinants of Axon Regeneration. Developmental Neurobiology. 78: 890-897. PMID 30345655 DOI: 10.1002/Dneu.22637  0.445
2018 Burnside ER, De Winter F, Didangelos A, James ND, Andreica EC, Layard-Horsfall H, Muir EM, Verhaagen J, Bradbury EJ. Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury. Brain : a Journal of Neurology. PMID 29912283 DOI: 10.1093/Brain/Awy158  0.347
2018 Attwell CL, van Zwieten M, Verhaagen J, Rj Mason M. The dorsal column lesion model of spinal cord injury and its use in deciphering the neuron-intrinsic injury response. Developmental Neurobiology. PMID 29717546 DOI: 10.1002/Dneu.22601  0.435
2018 Nieuwenhuis B, Haenzi B, Andrews MR, Verhaagen J, Fawcett JW. Integrins promote axonal regeneration after injury of the nervous system. Biological Reviews of the Cambridge Philosophical Society. PMID 29446228 DOI: 10.1111/Brv.12398  0.413
2017 Korecka JA, Moloney EB, Eggers R, Hobo B, Scheffer S, Ras-Verloop N, Pasterkamp RJ, Swaab DF, Smit AB, van Kesteren RE, Bossers K, Verhaagen J. Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 9361-9379. PMID 28842419 DOI: 10.1523/Jneurosci.0084-17.2017  0.522
2017 Moloney EB, Hobo B, De Winter F, Verhaagen J. Expression of a Mutant SEMA3A Protein with Diminished Signalling Capacity Does Not Alter ALS-Related Motor Decline, or Confer Changes in NMJ Plasticity after BotoxA-Induced Paralysis of Male Gastrocnemic Muscle. Plos One. 12: e0170314. PMID 28103314 DOI: 10.1371/Journal.Pone.0170314  0.376
2016 Andrews MR, Soleman S, Cheah M, Tumbarello DA, Mason MR, Moloney E, Verhaagen J, Bensadoun JC, Schneider B, Aebischer P, Fawcett JW. Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent. Eneuro. 3. PMID 27570822 DOI: 10.1523/ENEURO.0029-16.2016  0.342
2016 O'Neill P, Lindsay SL, Pantiru A, Guimond SE, Fagoe N, Verhaagen J, Turnbull JE, Riddell JS, Barnett SC. Sulfatase-mediated manipulation of the astrocyte-Schwann cell interface. Glia. PMID 27535874 DOI: 10.1002/Glia.23047  0.354
2016 Cheah M, Andrews MR, Chew DJ, Moloney EB, Verhaagen J, Fässler R, Fawcett JW. Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7283-97. PMID 27383601 DOI: 10.1523/Jneurosci.0901-16.2016  0.408
2016 de Winter F, Kwok JC, Fawcett JW, Vo TT, Carulli D, Verhaagen J. The Chemorepulsive Protein Semaphorin 3A and Perineuronal Net-Mediated Plasticity. Neural Plasticity. 2016: 3679545. PMID 27057361 DOI: 10.1155/2016/3679545  0.415
2015 Riaz M, Raz Y, Moloney EB, van Putten M, Krom YD, van der Maarel SM, Verhaagen J, Raz V. Differential myofiber-type transduction preference of adeno-associated virus serotypes 6 and 9. Skeletal Muscle. 5: 37. PMID 26561520 DOI: 10.1186/S13395-015-0064-4  0.328
2015 Huang Y, Skwarek-Maruszewska A, Horré K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, ... Verhaagen J, et al. Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models. Science Translational Medicine. 7: 309ra164. PMID 26468326 DOI: 10.1126/Scitranslmed.Aab3492  0.442
2015 Eggers R, Tannemaat MR, De Winter F, Malessy MJ, Verhaagen J. Clinical and neurobiological advances in promoting regeneration of the ventral root avulsion lesion. The European Journal of Neuroscience. PMID 26415525 DOI: 10.1111/Ejn.13089  0.417
2015 Fagoe ND, Attwell CL, Kouwenhoven D, Verhaagen J, Mason MR. Over-expression of ATF3 or the combination of ATF3, c-Jun, STAT3 and Smad1 promotes regeneration of the central axon branch of sensory neurons but without synergistic effects. Human Molecular Genetics. PMID 26385639 DOI: 10.1093/Hmg/Ddv383  0.472
2015 Hoyng SA, de Winter F, Tannemaat MR, Blits B, Malessy MJ, Verhaagen J. Gene therapy and peripheral nerve repair: a perspective. Frontiers in Molecular Neuroscience. 8: 32. PMID 26236188 DOI: 10.3389/Fnmol.2015.00032  0.341
2015 van Vliet AC, Tannemaat MR, van Duinen SG, Verhaagen J, Malessy MJ, De Winter F. Human Neuroma-in-Continuity Contains Focal Deficits in Myelination. Journal of Neuropathology and Experimental Neurology. 74: 901-11. PMID 26226133 DOI: 10.1097/Nen.0000000000000229  0.376
2015 van der Kallen LR, Eggers R, Ehlert EM, Verhaagen J, Smit AB, van Kesteren RE. Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo. Plos One. 10: e0127163. PMID 25993115 DOI: 10.1371/Journal.Pone.0127163  0.48
2015 Hoyng SA, De Winter F, Gnavi S, van Egmond L, Attwell CL, Tannemaat MR, Verhaagen J, Malessy MJ. Gene delivery to rat and human Schwann cells and nerve segments: a comparison of AAV 1-9 and lentiviral vectors. Gene Therapy. PMID 25938190 DOI: 10.1038/Gt.2015.47  0.394
2014 Mecollari V, Nieuwenhuis B, Verhaagen J. A perspective on the role of class III semaphorin signaling in central nervous system trauma. Frontiers in Cellular Neuroscience. 8: 328. PMID 25386118 DOI: 10.3389/Fncel.2014.00328  0.365
2014 Roet KC, Wirz KT, Franssen EH, Verhaagen J. A role for neuropilins in the interaction between Schwann cells and meningeal cells. Plos One. 9: e109401. PMID 25314276 DOI: 10.1371/Journal.Pone.0109401  0.385
2014 Fagoe ND, van Heest J, Verhaagen J. Spinal cord injury and the neuron-intrinsic regeneration-associated gene program. Neuromolecular Medicine. 16: 799-813. PMID 25269879 DOI: 10.1007/S12017-014-8329-3  0.457
2014 Moloney EB, de Winter F, Verhaagen J. ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease. Frontiers in Neuroscience. 8: 252. PMID 25177267 DOI: 10.3389/Fnins.2014.00252  0.323
2014 Hoyng SA, De Winter F, Gnavi S, de Boer R, Boon LI, Korvers LM, Tannemaat MR, Malessy MJ, Verhaagen J. A comparative morphological, electrophysiological and functional analysis of axon regeneration through peripheral nerve autografts genetically modified to overexpress BDNF, CNTF, GDNF, NGF, NT3 or VEGF. Experimental Neurology. 261: 578-93. PMID 25128265 DOI: 10.1016/J.Expneurol.2014.08.002  0.442
2014 Allodi I, Mecollari V, González-Pérez F, Eggers R, Hoyng S, Verhaagen J, Navarro X, Udina E. Schwann cells transduced with a lentiviral vector encoding Fgf-2 promote motor neuron regeneration following sciatic nerve injury. Glia. 62: 1736-46. PMID 24989458 DOI: 10.1002/Glia.22712  0.459
2014 Roet KC, Verhaagen J. Understanding the neural repair-promoting properties of olfactory ensheathing cells. Experimental Neurology. 261: 594-609. PMID 24842489 DOI: 10.1016/J.Expneurol.2014.05.007  0.437
2014 Bartus K, James ND, Didangelos A, Bosch KD, Verhaagen J, Yáñez-Muñoz RJ, Rogers JH, Schneider BL, Muir EM, Bradbury EJ. Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4822-36. PMID 24695702 DOI: 10.1523/Jneurosci.4369-13.2014  0.354
2014 Hoyng SA, Gnavi S, de Winter F, Eggers R, Ozawa T, Zaldumbide A, Hoeben RC, Malessy MJ, Verhaagen J. Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve. Gene Therapy. 21: 549-57. PMID 24694534 DOI: 10.1038/Gt.2014.22  0.417
2014 Giacobini P, Parkash J, Campagne C, Messina A, Casoni F, Vanacker C, Langlet F, Hobo B, Cagnoni G, Gallet S, Hanchate NK, Mazur D, Taniguchi M, Mazzone M, Verhaagen J, et al. Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A. Plos Biology. 12: e1001808. PMID 24618750 DOI: 10.1371/Journal.Pbio.1001808  0.385
2014 Alves JN, Muir EM, Andrews MR, Ward A, Michelmore N, Dasgupta D, Verhaagen J, Moloney EB, Keynes RJ, Fawcett JW, Rogers JH. AAV vector-mediated secretion of chondroitinase provides a sensitive tracer for axonal arborisations. Journal of Neuroscience Methods. 227: 107-20. PMID 24583077 DOI: 10.1016/J.Jneumeth.2014.02.010  0.422
2014 Fagoe ND, Eggers R, Verhaagen J, Mason MR. A compact dual promoter adeno-associated viral vector for efficient delivery of two genes to dorsal root ganglion neurons. Gene Therapy. 21: 242-52. PMID 24285216 DOI: 10.1038/Gt.2013.71  0.475
2014 de Ruiter GC, Spinner RJ, Verhaagen J, Malessy MJ. Misdirection and guidance of regenerating axons after experimental nerve injury and repair. Journal of Neurosurgery. 120: 493-501. PMID 24116727 DOI: 10.3171/2013.8.Jns122300  0.419
2014 Wirz KT, Keitel S, Swaab DF, Verhaagen J, Bossers K. Early molecular changes in Alzheimer disease: can we catch the disease in its presymptomatic phase? Journal of Alzheimer's Disease : Jad. 38: 719-40. PMID 24072070 DOI: 10.3233/Jad-130920  0.416
2014 Petrova IM, Malessy MJ, Verhaagen J, Fradkin LG, Noordermeer JN. Wnt signaling through the Ror receptor in the nervous system. Molecular Neurobiology. 49: 303-15. PMID 23990374 DOI: 10.1007/S12035-013-8520-9  0.322
2013 Lau P, Bossers K, Janky R, Salta E, Frigerio CS, Barbash S, Rothman R, Sierksma AS, Thathiah A, Greenberg D, Papadopoulou AS, Achsel T, Ayoubi T, Soreq H, Verhaagen J, et al. Alteration of the microRNA network during the progression of Alzheimer's disease. Embo Molecular Medicine. 5: 1613-34. PMID 24014289 DOI: 10.1002/Emmm.201201974  0.401
2013 Eggers R, de Winter F, Hoyng SA, Roet KC, Ehlert EM, Malessy MJ, Verhaagen J, Tannemaat MR. Lentiviral vector-mediated gradients of GDNF in the injured peripheral nerve: effects on nerve coil formation, Schwann cell maturation and myelination. Plos One. 8: e71076. PMID 23951085 DOI: 10.1371/Journal.Pone.0071076  0.431
2013 Godinho MJ, Teh L, Pollett MA, Goodman D, Hodgetts SI, Sweetman I, Walters M, Verhaagen J, Plant GW, Harvey AR. Immunohistochemical, ultrastructural and functional analysis of axonal regeneration through peripheral nerve grafts containing Schwann cells expressing BDNF, CNTF or NT3. Plos One. 8: e69987. PMID 23950907 DOI: 10.1371/Journal.Pone.0069987  0.409
2013 Dick G, Tan CL, Alves JN, Ehlert EM, Miller GM, Hsieh-Wilson LC, Sugahara K, Oosterhof A, van Kuppevelt TH, Verhaagen J, Fawcett JW, Kwok JC. Semaphorin 3A binds to the perineuronal nets via chondroitin sulfate type E motifs in rodent brains. The Journal of Biological Chemistry. 288: 27384-95. PMID 23940048 DOI: 10.1074/Jbc.M111.310029  0.314
2013 de Winter F, Hoyng S, Tannemaat M, Eggers R, Mason M, Malessy M, Verhaagen J. Gene therapy approaches to enhance regeneration of the injured peripheral nerve. European Journal of Pharmacology. 719: 145-52. PMID 23872403 DOI: 10.1016/J.Ejphar.2013.04.057  0.424
2013 Roet KC, Franssen EH, de Bree FM, Essing AH, Zijlstra SJ, Fagoe ND, Eggink HM, Eggers R, Smit AB, van Kesteren RE, Verhaagen J. A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11116-35. PMID 23825416 DOI: 10.1523/Jneurosci.1002-13.2013  0.455
2013 Korecka JA, van Kesteren RE, Blaas E, Spitzer SO, Kamstra JH, Smit AB, Swaab DF, Verhaagen J, Bossers K. Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling. Plos One. 8: e63862. PMID 23724009 DOI: 10.1371/Journal.Pone.0063862  0.481
2013 Vo T, Carulli D, Ehlert EM, Kwok JC, Dick G, Mecollari V, Moloney EB, Neufeld G, de Winter F, Fawcett JW, Verhaagen J. The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain. Molecular and Cellular Neurosciences. 56: 186-200. PMID 23665579 DOI: 10.1016/J.Mcn.2013.04.009  0.396
2013 Korecka JA, Eggers R, Swaab DF, Bossers K, Verhaagen J. Modeling early Parkinson's disease pathology with chronic low dose MPTP treatment. Restorative Neurology and Neuroscience. 31: 155-67. PMID 23271419 DOI: 10.3233/Rnn-110222  0.459
2013 Wirz KT, Bossers K, Stargardt A, Kamphuis W, Swaab DF, Hol EM, Verhaagen J. Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model. Neurobiology of Aging. 34: 1328-42. PMID 23245294 DOI: 10.1016/J.Neurobiolaging.2012.11.008  0.635
2012 Verhaagen J, Van Kesteren RE, Bossers KA, Macgillavry HD, Mason MR, Smit AB. Molecular target discovery for neural repair in the functional genomics era. Handbook of Clinical Neurology. 109: 595-616. PMID 23098739 DOI: 10.1016/B978-0-444-52137-8.00037-1  0.387
2012 Bosch KD, Bradbury EJ, Verhaagen J, Fawcett JW, McMahon SB. Chondroitinase ABC promotes plasticity of spinal reflexes following peripheral nerve injury. Experimental Neurology. 238: 64-78. PMID 22917776 DOI: 10.1016/J.Expneurol.2012.08.003  0.365
2012 Shakhbazau A, Kawasoe J, Hoyng SA, Kumar R, van Minnen J, Verhaagen J, Midha R. Early regenerative effects of NGF-transduced Schwann cells in peripheral nerve repair. Molecular and Cellular Neurosciences. 50: 103-12. PMID 22735691 DOI: 10.1016/J.Mcn.2012.04.004  0.432
2012 Wijte D, McDonnell LA, Balog CI, Bossers K, Deelder AM, Swaab DF, Verhaagen J, Mayboroda OA. A novel peptidomics approach to detect markers of Alzheimer's disease in cerebrospinal fluid. Methods (San Diego, Calif.). 56: 500-7. PMID 22465281 DOI: 10.1016/J.Ymeth.2012.03.018  0.435
2012 Roet KC, Eggers R, Verhaagen J. Noninvasive bioluminescence imaging of olfactory ensheathing glia and schwann cells following transplantation into the lesioned rat spinal cord. Cell Transplantation. 21: 1853-65. PMID 22449606 DOI: 10.3727/096368911X627471  0.301
2012 Hutson TH, Verhaagen J, Yáñez-Muñoz RJ, Moon LD. Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector. Gene Therapy. 19: 49-60. PMID 21562590 DOI: 10.1038/Gt.2011.71  0.376
2012 Van Den Berge SA, Van Strien ME, Korecka JA, Dijkstra AA, Sluijs JA, Kooijman L, Eggers R, De Filippis L, Vescovi AL, Verhaagen J, Van De Berg WDJ, Hol EM. Reply: Quantitative evaluation of the human subventricular zone Brain. 135: e222. DOI: 10.1093/Brain/Aws088  0.511
2011 van Kesteren RE, Mason MR, Macgillavry HD, Smit AB, Verhaagen J. A gene network perspective on axonal regeneration. Frontiers in Molecular Neuroscience. 4: 46. PMID 22125511 DOI: 10.3389/Fnmol.2011.00046  0.482
2011 van den Berge SA, van Strien ME, Korecka JA, Dijkstra AA, Sluijs JA, Kooijman L, Eggers R, De Filippis L, Vescovi AL, Verhaagen J, van de Berg WD, Hol EM. The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain. Brain : a Journal of Neurology. 134: 3249-63. PMID 22075520 DOI: 10.1093/Brain/Awr256  0.532
2011 Hoyng SA, Tannemaat MR, De Winter F, Verhaagen J, Malessy MJ. Nerve surgery and gene therapy: a neurobiological and clinical perspective. The Journal of Hand Surgery, European Volume. 36: 735-46. PMID 21914696 DOI: 10.1177/1753193411420348  0.355
2011 Zhao RR, Muir EM, Alves JN, Rickman H, Allan AY, Kwok JC, Roet KC, Verhaagen J, Schneider BL, Bensadoun JC, Ahmed SG, Yáñez-Muñoz RJ, Keynes RJ, Fawcett JW, Rogers JH. Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons. Journal of Neuroscience Methods. 201: 228-38. PMID 21855577 DOI: 10.1016/J.Jneumeth.2011.08.003  0.414
2011 Nandoe Tewarie RD, Bossers K, Ritfeld GJ, Blits B, Grotenhuis JA, Verhaagen J, Oudega M. Early passage bone marrow stromal cells express genes involved in nervous system development supporting their relevance for neural repair. Restorative Neurology and Neuroscience. 29: 187-201. PMID 21586825 DOI: 10.3233/Rnn-2011-0591  0.358
2011 Geeven G, Macgillavry HD, Eggers R, Sassen MM, Verhaagen J, Smit AB, de Gunst MC, van Kesteren RE. LLM3D: a log-linear modeling-based method to predict functional gene regulatory interactions from genome-wide expression data. Nucleic Acids Research. 39: 5313-27. PMID 21422075 DOI: 10.1093/Nar/Gkr139  0.335
2011 Mason MR, Tannemaat MR, Malessy MJ, Verhaagen J. Gene therapy for the peripheral nervous system: a strategy to repair the injured nerve? Current Gene Therapy. 11: 75-89. PMID 21291360 DOI: 10.2174/156652311794940764  0.442
2011 Hellström M, Muhling J, Ehlert EM, Verhaagen J, Pollett MA, Hu Y, Harvey AR. Negative impact of rAAV2 mediated expression of SOCS3 on the regeneration of adult retinal ganglion cell axons. Molecular and Cellular Neurosciences. 46: 507-15. PMID 21145973 DOI: 10.1016/J.Mcn.2010.12.003  0.458
2011 MacGillavry HD, Cornelis J, van der Kallen LR, Sassen MM, Verhaagen J, Smit AB, van Kesteren RE. Genome-wide gene expression and promoter binding analysis identifies NFIL3 as a repressor of C/EBP target genes in neuronal outgrowth. Molecular and Cellular Neurosciences. 46: 460-8. PMID 21112399 DOI: 10.1016/J.Mcn.2010.11.011  0.367
2010 Bossers K, Wirz KT, Meerhoff GF, Essing AH, van Dongen JW, Houba P, Kruse CG, Verhaagen J, Swaab DF. Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease. Brain : a Journal of Neurology. 133: 3699-723. PMID 20889584 DOI: 10.1093/Brain/Awq258  0.472
2010 Aartsen WM, van Cleef KW, Pellissier LP, Hoek RM, Vos RM, Blits B, Ehlert EM, Balaggan KS, Ali RR, Verhaagen J, Wijnholds J. GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors. Plos One. 5: e12387. PMID 20808778 DOI: 10.1371/Journal.Pone.0012387  0.347
2010 Mamber C, Verhaagen J, Hol EM. In vivo targeting of subventricular zone astrocytes. Progress in Neurobiology. 92: 19-32. PMID 20441785 DOI: 10.1016/J.Pneurobio.2010.04.007  0.59
2010 Mason MR, Ehlert EM, Eggers R, Pool CW, Hermening S, Huseinovic A, Timmermans E, Blits B, Verhaagen J. Comparison of AAV serotypes for gene delivery to dorsal root ganglion neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 715-24. PMID 20179682 DOI: 10.1038/Mt.2010.19  0.418
2010 Ehlert EM, Eggers R, Niclou SP, Verhaagen J. Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system. Bmc Neuroscience. 11: 20. PMID 20167052 DOI: 10.1186/1471-2202-11-20  0.453
2010 Blits B, Derks S, Twisk J, Ehlert E, Prins J, Verhaagen J. Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors. Journal of Neuroscience Methods. 185: 257-63. PMID 19850079 DOI: 10.1016/J.Jneumeth.2009.10.009  0.39
2010 Eggers R, Tannemaat MR, Ehlert EM, Verhaagen J. A spatio-temporal analysis of motoneuron survival, axonal regeneration and neurotrophic factor expression after lumbar ventral root avulsion and implantation. Experimental Neurology. 223: 207-20. PMID 19646436 DOI: 10.1016/J.Expneurol.2009.07.021  0.438
2009 MacGillavry HD, Stam FJ, Sassen MM, Kegel L, Hendriks WT, Verhaagen J, Smit AB, van Kesteren RE. NFIL3 and cAMP response element-binding protein form a transcriptional feedforward loop that controls neuronal regeneration-associated gene expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15542-50. PMID 20007478 DOI: 10.1523/Jneurosci.3938-09.2009  0.803
2009 Verhaagen J, Swaab DF. The eighteenth C.U. Ariëns Kappers lecture: an introduction. Progress in Brain Research. 175: 497-9. PMID 19660676 DOI: 10.1016/S0079-6123(09)17533-7  0.407
2009 Tannemaat MR, Boer GJ, Eggers R, Malessy MJ, Verhaagen J. From microsurgery to nanosurgery: how viral vectors may help repair the peripheral nerve. Progress in Brain Research. 175: 173-86. PMID 19660656 DOI: 10.1016/S0079-6123(09)17512-X  0.394
2009 Harvey AR, Ehlert E, de Wit J, Drummond ES, Pollett MA, Ruitenberg M, Plant GW, Verhaagen J, Levelt CN. Use of GFP to analyze morphology, connectivity, and function of cells in the central nervous system. Methods in Molecular Biology (Clifton, N.J.). 515: 63-95. PMID 19378117 DOI: 10.1007/978-1-59745-559-6_5  0.301
2009 Franssen EH, Roet KC, de Bree FM, Verhaagen J. Olfactory ensheathing glia and Schwann cells exhibit a distinct interaction behavior with meningeal cells. Journal of Neuroscience Research. 87: 1556-64. PMID 19140223 DOI: 10.1002/Jnr.21979  0.341
2009 Vukovic J, Ruitenberg MJ, Roet K, Franssen E, Arulpragasam A, Sasaki T, Verhaagen J, Harvey AR, Busfield SJ, Plant GW. The glycoprotein fibulin-3 regulates morphology and motility of olfactory ensheathing cells in vitro. Glia. 57: 424-43. PMID 18803302 DOI: 10.1002/glia.20771  0.317
2009 Bossers K, Meerhoff G, Balesar R, van Dongen JW, Kruse CG, Swaab DF, Verhaagen J. Analysis of gene expression in Parkinson's disease: possible involvement of neurotrophic support and axon guidance in dopaminergic cell death. Brain Pathology (Zurich, Switzerland). 19: 91-107. PMID 18462474 DOI: 10.1111/J.1750-3639.2008.00171.X  0.495
2008 Tannemaat MR, Verhaagen J, Malessy M. The application of viral vectors to enhance regeneration after peripheral nerve repair. Neurological Research. 30: 1039-46. PMID 19079978 DOI: 10.1179/174313208X362514  0.393
2008 Tannemaat MR, Eggers R, Hendriks WT, de Ruiter GC, van Heerikhuize JJ, Pool CW, Malessy MJ, Boer GJ, Verhaagen J. Differential effects of lentiviral vector-mediated overexpression of nerve growth factor and glial cell line-derived neurotrophic factor on regenerating sensory and motor axons in the transected peripheral nerve. The European Journal of Neuroscience. 28: 1467-79. PMID 18973572 DOI: 10.1111/J.1460-9568.2008.06452.X  0.477
2008 Franssen EH, De Bree FM, Essing AH, Ramon-Cueto A, Verhaagen J. Comparative gene expression profiling of olfactory ensheathing glia and Schwann cells indicates distinct tissue repair characteristics of olfactory ensheathing glia. Glia. 56: 1285-98. PMID 18615567 DOI: 10.1002/Glia.20697  0.438
2008 Eggers R, Hendriks WT, Tannemaat MR, van Heerikhuize JJ, Pool CW, Carlstedt TP, Zaldumbide A, Hoeben RC, Boer GJ, Verhaagen J. Neuroregenerative effects of lentiviral vector-mediated GDNF expression in reimplanted ventral roots. Molecular and Cellular Neurosciences. 39: 105-17. PMID 18585464 DOI: 10.1016/J.Mcn.2008.05.018  0.458
2008 Stam FJ, Mason MRJ, Smit AB, Verhaagen J. A Meta-Analysis of Large-Scale Gene Expression Studies of the Injured PNS: Toward the Genetic Networks That Govern Successful Regeneration Neural Degeneration and Repair: Gene Expression Profiling, Proteomics and Systems Biology. 35-59. DOI: 10.1002/9783527622467.ch2  0.752
2007 Tannemaat MR, Boer GJ, Verhaagen J, Malessy MJ. Genetic modification of human sural nerve segments by a lentiviral vector encoding nerve growth factor. Neurosurgery. 61: 1286-94; discussion . PMID 18162909 DOI: 10.1227/01.Neu.0000306108.78044.A2  0.371
2007 Tannemaat MR, Korecka J, Ehlert EM, Mason MR, van Duinen SG, Boer GJ, Malessy MJ, Verhaagen J. Human neuroma contains increased levels of semaphorin 3A, which surrounds nerve fibers and reduces neurite extension in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14260-4. PMID 18160633 DOI: 10.1523/Jneurosci.4571-07.2007  0.401
2007 Franssen EH, de Bree FM, Verhaagen J. Olfactory ensheathing glia: their contribution to primary olfactory nervous system regeneration and their regenerative potential following transplantation into the injured spinal cord. Brain Research Reviews. 56: 236-58. PMID 17884174 DOI: 10.1016/J.Brainresrev.2007.07.013  0.39
2007 Hendriks WT, Eggers R, Verhaagen J, Boer GJ. Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells. Journal of Neuroscience Research. 85: 3041-52. PMID 17671987 DOI: 10.1002/Jnr.21432  0.421
2007 Korecka JA, Verhaagen J, Hol EM. Cell-replacement and gene-therapy strategies for Parkinson's and Alzheimer's disease. Regenerative Medicine. 2: 425-46. PMID 17635050 DOI: 10.2217/17460751.2.4.425  0.553
2007 Stam FJ, MacGillavry HD, Armstrong NJ, de Gunst MC, Zhang Y, van Kesteren RE, Smit AB, Verhaagen J. Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury. The European Journal of Neuroscience. 25: 3629-37. PMID 17610582 DOI: 10.1111/J.1460-9568.2007.05597.X  0.816
2007 de Wit J, Verhaagen J. Proteoglycans as modulators of axon guidance cue function. Advances in Experimental Medicine and Biology. 600: 73-89. PMID 17607948 DOI: 10.1007/978-0-387-70956-7_7  0.4
2007 Zhang Y, Zhang X, Wu D, Verhaagen J, Richardson PM, Yeh J, Bo X. Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory axons into spinal cord. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1796-804. PMID 17551503 DOI: 10.1038/Sj.Mt.6300220  0.424
2007 Stam FJ, MacGillavry HD, Armstrong NJ, De Gunst MCM, Zhang Y, Van Kesteren RE, Smit AB, Verhaagen J. CORRIGENDUM: Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury European Journal of Neuroscience. 26: 1078-1078. DOI: 10.1111/J.1460-9568.2007.05791.X  0.337
2006 Tervonen TA, Ajamian F, De Wit J, Verhaagen J, Castrén E, Castrén M. Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors. The European Journal of Neuroscience. 24: 1277-85. PMID 16987215 DOI: 10.1111/J.1460-9568.2006.05010.X  0.324
2006 Harvey AR, Hu Y, Leaver SG, Mellough CB, Park K, Verhaagen J, Plant GW, Cui Q. Gene therapy and transplantation in CNS repair: the visual system. Progress in Retinal and Eye Research. 25: 449-89. PMID 16963308 DOI: 10.1016/J.Preteyeres.2006.07.002  0.399
2006 Pasterkamp RJ, Verhaagen J. Semaphorins in axon regeneration: developmental guidance molecules gone wrong? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 1499-511. PMID 16939971 DOI: 10.1098/Rstb.2006.1892  0.427
2006 de Wit J, Toonen RF, Verhaagen J, Verhage M. Vesicular trafficking of semaphorin 3A is activity-dependent and differs between axons and dendrites. Traffic (Copenhagen, Denmark). 7: 1060-77. PMID 16734664 DOI: 10.1111/J.1600-0854.2006.00442.X  0.391
2006 Leaver SG, Cui Q, Plant GW, Arulpragasam A, Hisheh S, Verhaagen J, Harvey AR. AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells. Gene Therapy. 13: 1328-41. PMID 16708079 DOI: 10.1038/Sj.Gt.3302791  0.414
2006 De Winter F, Vo T, Stam FJ, Wisman LA, Bär PR, Niclou SP, van Muiswinkel FL, Verhaagen J. The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease. Molecular and Cellular Neurosciences. 32: 102-17. PMID 16677822 DOI: 10.1016/J.Mcn.2006.03.002  0.776
2006 Niclou SP, Ehlert EM, Verhaagen J. Chemorepellent axon guidance molecules in spinal cord injury. Journal of Neurotrauma. 23: 409-21. PMID 16629626 DOI: 10.1089/Neu.2006.23.409  0.42
2006 De Wit J, Eggers R, Evers R, Castrén E, Verhaagen J. Long-term adeno-associated viral vector-mediated expression of truncated TrkB in the adult rat facial nucleus results in motor neuron degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1516-30. PMID 16452675 DOI: 10.1523/Jneurosci.4543-05.2006  0.397
2005 Zhang Y, Bo X, Schoepfer R, Holtmaat AJ, Verhaagen J, Emson PC, Lieberman AR, Anderson PN. Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 14883-8. PMID 16195382 DOI: 10.1073/Pnas.0505164102  0.795
2005 Hu Y, Leaver SG, Plant GW, Hendriks WT, Niclou SP, Verhaagen J, Harvey AR, Cui Q. Lentiviral-mediated transfer of CNTF to schwann cells within reconstructed peripheral nerve grafts enhances adult retinal ganglion cell survival and axonal regeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 906-15. PMID 15922961 DOI: 10.1016/J.Ymthe.2005.01.016  0.419
2005 De Wit J, De Winter F, Klooster J, Verhaagen J. Semaphorin 3A displays a punctate distribution on the surface of neuronal cells and interacts with proteoglycans in the extracellular matrix. Molecular and Cellular Neurosciences. 29: 40-55. PMID 15866045 DOI: 10.1016/J.Mcn.2004.12.009  0.403
2005 Jiménez CR, Stam FJ, Li KW, Gouwenberg Y, Hornshaw MP, De Winter F, Verhaagen J, Smit AB. Proteomics of the injured rat sciatic nerve reveals protein expression dynamics during regeneration. Molecular & Cellular Proteomics : McP. 4: 120-32. PMID 15509515 DOI: 10.1074/Mcp.M400076-Mcp200  0.788
2004 Ahmed BY, Chakravarthy S, Eggers R, Hermens WT, Zhang JY, Niclou SP, Levelt C, Sablitzky F, Anderson PN, Lieberman AR, Verhaagen J. Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors. Bmc Neuroscience. 5: 4. PMID 15005815 DOI: 10.1186/1471-2202-5-4  0.401
2004 Dillon TE, Saldanha J, Giger R, Verhaagen J, Rochlin MW. Sema3A regulates the timing of target contact by cranial sensory axons. The Journal of Comparative Neurology. 470: 13-24. PMID 14755522 DOI: 10.1002/Cne.11029  0.384
2004 Hendriks WT, Ruitenberg MJ, Blits B, Boer GJ, Verhaagen J. Viral vector-mediated gene transfer of neurotrophins to promote regeneration of the injured spinal cord. Progress in Brain Research. 146: 451-76. PMID 14699980 DOI: 10.1016/S0079-6123(03)46029-9  0.31
2003 Shearer MC, Niclou SP, Brown D, Asher RA, Holtmaat AJ, Levine JM, Verhaagen J, Fawcett JW. The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways. Molecular and Cellular Neurosciences. 24: 913-25. PMID 14697658 DOI: 10.1016/J.Mcn.2003.09.004  0.783
2003 Niclou SP, Franssen EH, Ehlert EM, Taniguchi M, Verhaagen J. Meningeal cell-derived semaphorin 3A inhibits neurite outgrowth. Molecular and Cellular Neurosciences. 24: 902-12. PMID 14697657 DOI: 10.1016/S1044-7431(03)00243-4  0.415
2003 de Wit J, Verhaagen J. Role of semaphorins in the adult nervous system. Progress in Neurobiology. 71: 249-67. PMID 14687984 DOI: 10.1016/J.Pneurobio.2003.06.001  0.442
2003 Ruitenberg MJ, Plant GW, Hamers FP, Wortel J, Blits B, Dijkhuizen PA, Gispen WH, Boer GJ, Verhaagen J. Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7045-58. PMID 12904465  0.581
2003 Holtmaat AJ, Gorter JA, De Wit J, Tolner EA, Spijker S, Giger RJ, Lopes da Silva FH, Verhaagen J. Transient downregulation of Sema3A mRNA in a rat model for temporal lobe epilepsy. A novel molecular event potentially contributing to mossy fiber sprouting. Experimental Neurology. 182: 142-50. PMID 12821384 DOI: 10.1016/S0014-4886(03)00035-9  0.774
2003 Blits B, Oudega M, Boer GJ, Bartlett Bunge M, Verhaagen J. Adeno-associated viral vector-mediated neurotrophin gene transfer in the injured adult rat spinal cord improves hind-limb function. Neuroscience. 118: 271-81. PMID 12676157 DOI: 10.1016/S0306-4522(02)00970-3  0.427
2002 De Winter F, Holtmaat AJ, Verhaagen J. Neuropilin and class 3 semaphorins in nervous system regeneration. Advances in Experimental Medicine and Biology. 515: 115-39. PMID 12613548 DOI: 10.1007/978-1-4615-0119-0_10  0.802
2002 Holtmaat AJ, De Winter F, De Wit J, Gorter JA, da Silva FH, Verhaagen J. Semaphorins: contributors to structural stability of hippocampal networks? Progress in Brain Research. 138: 17-38. PMID 12432760 DOI: 10.1016/S0079-6123(02)38068-3  0.712
2002 Blits B, Boer GJ, Verhaagen J. Pharmacological, cell, and gene therapy strategies to promote spinal cord regeneration. Cell Transplantation. 11: 593-613. PMID 12428749 DOI: 10.3727/000000002783985521  0.414
2002 Harvey AR, Kamphuis W, Eggers R, Symons NA, Blits B, Niclou S, Boer GJ, Verhaagen J. Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors. Molecular and Cellular Neurosciences. 21: 141-57. PMID 12359157 DOI: 10.1006/Mcne.2002.1168  0.375
2002 De Winter F, Oudega M, Lankhorst AJ, Hamers FP, Blits B, Ruitenberg MJ, Pasterkamp RJ, Gispen WH, Verhaagen J. Injury-induced class 3 semaphorin expression in the rat spinal cord. Experimental Neurology. 175: 61-75. PMID 12009760 DOI: 10.1006/exnr.2002.7884  0.562
2002 Verwer RW, Hermens WT, Dijkhuizen P, ter Brake O, Baker RE, Salehi A, Sluiter AA, Kok MJ, Muller LJ, Verhaagen J, Swaab DF. Cells in human postmortem brain tissue slices remain alive for several weeks in culture. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 54-60. PMID 11772936 DOI: 10.1096/Fj.01-0504Com  0.47
2002 Hofman MA, Boer GJ, Holtmaat AJGD, Van Someren EJW, Verhaagen J, Swaab DF. Plasticity in the adult brain: From genes to neurotherapy: Preface Progress in Brain Research. 138: ix-x. DOI: 10.1016/S0079-6123(02)38065-8  0.744
2001 De Vrij FM, Sluijs JA, Gregori L, Fischer DF, Hermens WT, Goldgaber D, Verhaagen J, Van Leeuwen FW, Hol EM. Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2680-8. PMID 11726544 DOI: 10.1096/Fj.01-0438Com  0.589
2001 Pasterkamp RJ, Verhaagen J. Emerging roles for semaphorins in neural regeneration. Brain Research. Brain Research Reviews. 35: 36-54. PMID 11245885 DOI: 10.1016/S0165-0173(00)00050-3  0.453
2001 Pasterkamp RJ, Anderson PN, Verhaagen J. Peripheral nerve injury fails to induce growth of lesioned ascending dorsal column axons into spinal cord scar tissue expressing the axon repellent Semaphorin3A. The European Journal of Neuroscience. 13: 457-71. PMID 11168552 DOI: 10.1046/J.0953-816X.2000.01398.X  0.455
2000 Blits B, Dijkhuizen PA, Boer GJ, Verhaagen J. Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function. Experimental Neurology. 164: 25-37. PMID 10877912 DOI: 10.1006/Exnr.2000.7413  0.425
2000 Rochlin MW, O'Connor R, Giger RJ, Verhaagen J, Farbman AI. Comparison of neurotrophin and repellent sensitivities of early embryonic geniculate and trigeminal axons. The Journal of Comparative Neurology. 422: 579-93. PMID 10861527 DOI: 10.1002/1096-9861(20000710)422:4<579::Aid-Cne7>3.0.Co;2-G  0.402
2000 Blits B, Dijkhuizen PA, Hermens WT, Van Esseveldt LK, Boer GJ, Verhaagen J. The use of adenoviral vectors and ex vivo transduced neurotransplants: towards promotion of neuroregeneration. Cell Transplantation. 9: 169-78. PMID 10811391  0.347
2000 Pasterkamp RJ, Giger RJ, Baker RE, Hermens WT, Verhaagen J. Ectopic adenoviral vector-directed expression of Sema3A in organotypic spinal cord explants inhibits growth of primary sensory afferents. Developmental Biology. 220: 129-41. PMID 10753505 DOI: 10.1006/Dbio.2000.9627  0.364
2000 Salehi A, Ocampo M, Verhaagen J, Swaab DF. P75 neurotrophin receptor in the nucleus basalis of meynert in relation to age, sex, and Alzheimer's disease. Experimental Neurology. 161: 245-58. PMID 10683291 DOI: 10.1006/Exnr.1999.7252  0.452
1999 Holtmaat AJ, Huizinga CT, Margolis FL, Gispen WH, Verhaagen J. Transgenic expression of B-50/GAP-43 in mature olfactory neurons triggers downregulation of native B-50/GAP-43 expression in immature olfactory neurons. Brain Research. Molecular Brain Research. 74: 197-207. PMID 10640691 DOI: 10.1016/S0169-328X(99)00263-6  0.814
1999 Blits B, Dijkhuizen PA, Carlstedt TP, Poldervaart H, Schiemanck S, Boer GJ, Verhaagen J. Adenoviral vector-mediated expression of a foreign gene in peripheral nerve tissue bridges implanted in the injured peripheral and central nervous system. Experimental Neurology. 160: 256-67. PMID 10630210 DOI: 10.1006/exnr.1999.7204  0.325
1999 Hermens WT, ter Brake O, Dijkhuizen PA, Sonnemans MA, Grimm D, Kleinschmidt JA, Verhaagen J. Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system. Human Gene Therapy. 10: 1885-91. PMID 10446928 DOI: 10.1089/10430349950017563  0.313
1999 Bamberg JA, Baumgartner S, Betz H, Bolz J, Chedotal A, Christensen CRL, Comoglio PM, Culotti JG, Doherty P, Drabkin H, Ensser A, Fishman MC, Fleckenstein B, Freeman GJ, Fujisawa H, ... ... Verhaagen J, et al. Unified nomenclature for the semaphorins/collapsins [1] Cell. 97: 551-552. PMID 10367884 DOI: 10.1016/S0092-8674(00)80766-7  0.488
1999 Pasterkamp RJ, Giger RJ, Ruitenberg MJ, Holtmaat AJ, De Wit J, De Winter F, Verhaagen J. Expression of the gene encoding the chemorepellent semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS. Molecular and Cellular Neurosciences. 13: 143-66. PMID 10192772 DOI: 10.1006/mcne.1999.0738  0.776
1998 Aarts LH, Schotman P, Verhaagen J, Schrama LH, Gispen WH. The role of the neural growth associated protein B-50/GAP-43 in morphogenesis. Advances in Experimental Medicine and Biology. 446: 85-106. PMID 10079839 DOI: 10.1007/978-1-4615-4869-0_6  0.61
1998 Pasterkamp RJ, De Winter F, Giger RJ, Verhaagen J. Role for semaphorin III and its receptor neuropilin-1 in neuronal regeneration and scar formation? Progress in Brain Research. 117: 151-70. PMID 9932407 DOI: 10.1016/S0079-6123(08)64014-5  0.479
1998 Giger RJ, Pasterkamp RJ, Holtmaat AJ, Verhaagen J. Semaphorin III: role in neuronal development and structural plasticity. Progress in Brain Research. 117: 133-49. PMID 9932406 DOI: 10.1016/S0079-6123(08)64013-3  0.782
1998 Salehi A, Verhaagen J, Swaab DF. Neurotrophin receptors in Alzheimer's disease. Progress in Brain Research. 117: 71-89. PMID 9932402 DOI: 10.1016/S0079-6123(08)64009-1  0.502
1998 Duckers HJ, van Dokkum RP, Verhaagen J, van Luijtelaar EL, Coenen AM, Lopes da Silva FH, Gispen WH. Neurotrophic ACTH4-9 analogue therapy normalizes electroencephalographic alterations in chronic experimental allergic encephalomyelitis. The European Journal of Neuroscience. 10: 3709-20. PMID 9875350 DOI: 10.1046/j.1460-9568.1998.00382.x  0.532
1998 Pasterkamp RJ, De Winter F, Holtmaat AJ, Verhaagen J. Evidence for a role of the chemorepellent semaphorin III and its receptor neuropilin-1 in the regeneration of primary olfactory axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9962-76. PMID 9822752 DOI: 10.1523/Jneurosci.18-23-09962.1998  0.795
1998 Zhang Y, Dijkhuizen PA, Anderson PN, Lieberman AR, Verhaagen J. NT-3 delivered by an adenoviral vector induces injured dorsal root axons to regenerate into the spinal cord of adult rats. Journal of Neuroscience Research. 54: 554-62. PMID 9822165 DOI: 10.1002/(Sici)1097-4547(19981115)54:4<554::Aid-Jnr12>3.0.Co;2-M  0.413
1998 Hermens WT, Verhaagen J. Suppression of inflammation by dexamethasone prolongs adenoviral vector-mediated transgene expression in the facial nucleus of the rat. Brain Research Bulletin. 47: 133-40. PMID 9820730 DOI: 10.1016/S0361-9230(98)00042-2  0.339
1998 Pasterkamp RJ, Giger RJ, Verhaagen J. Regulation of semaphorin III/collapsin-1 gene expression during peripheral nerve regeneration. Experimental Neurology. 153: 313-27. PMID 9784290 DOI: 10.1006/Exnr.1998.6886  0.478
1998 Baker RE, Dijkhuizen PA, Van Pelt J, Verhaagen J. Growth of pyramidal, but not non-pyramidal, dendrites in long-term organotypic explants of neonatal rat neocortex chronically exposed to neurotrophin-3. The European Journal of Neuroscience. 10: 1037-44. PMID 9753171 DOI: 10.1046/J.1460-9568.1998.00118.X  0.366
1998 Hermens WT, Verhaagen J. Viral vectors, tools for gene transfer in the nervous system. Progress in Neurobiology. 55: 399-432. PMID 9654386 DOI: 10.1016/S0301-0082(98)00007-0  0.315
1998 Dijkhuizen PA, Pasterkamp RJ, Hermens WT, de Winter F, Giger RJ, Verhaagen J. Adenoviral vector-mediated gene delivery to injured rat peripheral nerve. Journal of Neurotrauma. 15: 387-97. PMID 9624624  0.322
1998 Holtmaat AJ, Oestreicher AB, Gispen WH, Verhaagen J. Manipulation of gene expression in the mammalian nervous system: application in the study of neurite outgrowth and neuroregeneration-related proteins. Brain Research. Brain Research Reviews. 26: 43-71. PMID 9600624 DOI: 10.1016/S0165-0173(97)00044-1  0.81
1998 Giger RJ, Pasterkamp RJ, Heijnen S, Holtmaat AJ, Verhaagen J. Anatomical distribution of the chemorepellent semaphorin III/collapsin-1 in the adult rat and human brain: predominant expression in structures of the olfactory-hippocampal pathway and the motor system. Journal of Neuroscience Research. 52: 27-42. PMID 9556027 DOI: 10.1002/(Sici)1097-4547(19980401)52:1<27::Aid-Jnr4>3.0.Co;2-M  0.79
1998 van Esseveldt KE, Hermens WT, Verhaagen J, Boer GJ. Transgene expression in rat fetal brain grafts is maintained for 7 months after ex vivo adenoviral vector-mediated gene transfer. Neuroscience Letters. 240: 116-20. PMID 9486486 DOI: 10.1016/S0304-3940(97)00934-8  0.348
1998 Van Leeuwen F, Salehi A, Giger R, Holtmaat A, Verhaagen J, Eikelboom T, Verweij W, Top W. Neuronal degeneration and regeneration: From basic mechanisms to prospects for therapy - Proceedings of the 20th International Summer School of Brain Research, held at the Royal Netherlands Academy of Sciences, Amsterdam, The Netherlands from 25 to 29 August 1997: Preface Progress in Brain Research. 117: xi-xii.  0.738
1997 Oestreicher AB, De Graan PN, Gispen WH, Verhaagen J, Schrama LH. B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system. Progress in Neurobiology. 53: 627-86. PMID 9447616 DOI: 10.1016/S0301-0082(97)00043-9  0.595
1997 Buffo A, Holtmaat AJ, Savio T, Verbeek JS, Oberdick J, Oestreicher AB, Gispen WH, Verhaagen J, Rossi F, Strata P. Targeted overexpression of the neurite growth-associated protein B-50/GAP-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8778-91. PMID 9348347 DOI: 10.1523/Jneurosci.17-22-08778.1997  0.825
1997 Holtmaat AJ, Hermens WT, Sonnemans MA, Giger RJ, Van Leeuwen FW, Kaplitt MG, Oestreicher AB, Gispen WH, Verhaagen J. Adenoviral vector-mediated expression of B-50/GAP-43 induces alterations in the membrane organization of olfactory axon terminals in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6575-86. PMID 9254670 DOI: 10.1523/Jneurosci.17-17-06575.1997  0.813
1997 Dijkhuizen PA, Hermens WT, Teunis MA, Verhaagen J. Adenoviral vector-directed expression of neurotrophin-3 in rat dorsal root ganglion explants results in a robust neurite outgrowth response. Journal of Neurobiology. 33: 172-84. PMID 9240373 DOI: 10.1002/(Sici)1097-4695(199708)33:2<172::Aid-Neu6>3.0.Co;2-#  0.442
1997 Boer GJ, van Esseveldt KE, Hermens WT, Liu R, Verhaagen J. Long-term transgene expression in fetal rat suprachiasmatic nucleus neurografts following ex vivo adenoviral vector-mediated gene transfer. Experimental Neurology. 145: 536-45. PMID 9217089 DOI: 10.1006/Exnr.1997.6489  0.325
1997 Hermens WT, Verhaagen J. Adenoviral vector-mediated gene expression in the nervous system of immunocompetent Wistar and T cell-deficient nude rats: preferential survival of transduced astroglial cells in nude rats. Human Gene Therapy. 8: 1049-63. PMID 9189763 DOI: 10.1089/Hum.1997.8.9-1049  0.362
1997 Duckers HJ, Muller HJ, Verhaagen J, Nicolay K, Gispen WH. Longitudinal in vivo magnetic resonance imaging studies in experimental allergic encephalomyelitis: effect of a neurotrophic treatment on cortical lesion development. Neuroscience. 77: 1163-73. PMID 9130795 DOI: 10.1016/S0306-4522(96)00514-3  0.515
1997 van Esseveldt KE, Liu R, Hermens WT, Verhaagen J, Boer GJ. Adenoviral vector-mediated gene transfer and neurotransplantation: possibilities and limitations in grafting of the fetal rat suprachiasmatic nucleus. Journal of Neuroscience Methods. 71: 113-23. PMID 9125380 DOI: 10.1016/S0165-0270(96)00131-8  0.351
1997 Hermens WT, Giger RJ, Holtmaat AJ, Dijkhuizen PA, Houweling DA, Verhaagen J. Transient gene transfer to neurons and glia: analysis of adenoviral vector performance in the CNS and PNS. Journal of Neuroscience Methods. 71: 85-98. PMID 9125378 DOI: 10.1016/S0165-0270(96)00129-X  0.783
1996 Duckers HJ, van Dokkum RP, Verhaagen J, Lopes da Silva FH, Gispen WH. Functional and neurophysiological evidence of the efficacy of trophic pharmacotherapy using an adrenocorticotrophic hormone4-9 analog in experimental allergic encephalomyelitis, an animal model of multiple sclerosis. Neuroscience. 71: 507-21. PMID 9053803 DOI: 10.1016/0306-4522(95)00451-3  0.549
1996 Salehi A, Verhaagen J, Dijkhuizen PA, Swaab DF. Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease. Neuroscience. 75: 373-87. PMID 8931004 DOI: 10.1016/0306-4522(96)00273-4  0.5
1996 Giger RJ, Wolfer DP, De Wit GM, Verhaagen J. Anatomy of rat semaphorin III/collapsin-1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis. The Journal of Comparative Neurology. 375: 378-92. PMID 8915837 DOI: 10.1002/(Sici)1096-9861(19961118)375:3<378::Aid-Cne3>3.0.Co;2-#  0.483
1996 Holtmaat AJ, Hermens WT, Oestreicher AB, Gispen WH, Kaplitt MG, Verhaagen J. Efficient adenoviral vector-directed expression of a foreign gene to neurons and sustentacular cells in the mouse olfactory neuroepithelium. Brain Research. Molecular Brain Research. 41: 148-56. PMID 8883946 DOI: 10.1016/0169-328X(96)00085-X  0.799
1996 Vogt L, Giger RJ, Ziegler U, Kunz B, Buchstaller A, Hermens WTJMC, Kaplitt MG, Rosenfeld MR, Pfaff DW, Verhaagen J, Sonderegger P. Continuous renewal of the axonal pathway sensor apparatus by insertion of new sensor molecules into the growth cone membrane. Current Biology : Cb. 6: 1153-8. PMID 8805367 DOI: 10.1016/S0960-9822(02)70682-9  0.353
1996 Hamers FP, Plantinga LC, Verhaagen J, Neijt JP, Gispen WH. Upregulation of B50/GAP-43 protein mRNA in rat dorsal root ganglia during cisplatin intoxication. Journal of Neuroscience Research. 44: 142-8. PMID 8723222 DOI: 10.1002/(SICI)1097-4547(19960415)44:2<142::AID-JNR6>3.0.CO;2-D  0.609
1995 Verhaagen J, Hermens WT, Dijkhuizen PA, Holtmaat AJ, Gispen WH. Use of viral vectors to promote neuroregeneration. Clinical Neuroscience (New York, N.Y.). 3: 275-83. PMID 8914794  0.801
1995 Holtmaat AJ, Dijkhuizen PA, Oestreicher AB, Romijn HJ, Van der Lugt NM, Berns A, Margolis FL, Gispen WH, Verhaagen J. Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular fiber growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7953-65. PMID 8613733 DOI: 10.1523/Jneurosci.15-12-07953.1995  0.823
1995 Zhang YP, Verhaagen J, Hamers FP, Gispen WH. [Elevated expression of B-50 (GAP-43) -mRNA in a subpopulation of olfactory bulb mitral cells following axotomy]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 47: 38-44. PMID 7784897  0.626
1995 Plantinga LC, Verhaagen J, Edwards PM, Hali M, Brakkee JH, Gispen WH. Pharmacological evidence for the involvement of endogenous alpha-MSH-like peptides in peripheral nerve regeneration. Peptides. 16: 319-24. PMID 7784262 DOI: 10.1016/0196-9781(94)00179-0  0.562
1994 Verhaagen J, Hermens WT, Kaplitt MG, Pfaff DW, Gispen WH. B-50/GAP-43 expression via a defective herpes simplex virus vector results in persistent morphological changes in non-neuronal cells. Gene Therapy. 1: S81. PMID 8542427  0.594
1994 Duckers HJ, Verhaagen J, de Bruijn E, Gispen WH. Effective use of a neurotrophic ACTH4-9 analogue in the treatment of a peripheral demyelinating syndrome (experimental allergic neuritis). An intervention study. Brain : a Journal of Neurology. 117: 365-74. PMID 8186962  0.57
1994 Plantinga LC, Verhaagen J, Wong SL, Edwards PM, Bär PR, Gispen WH. The neurotrophic peptide Org 2766 does not influence the expression of the immediate early gene c-fos following sciatic nerve crush in the rat. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 12: 117-25. PMID 7942087 DOI: 10.1016/0736-5748(94)90004-3  0.61
1994 Gispen WH, Verhaagen J, Bär D. ACTH/MSH-derived peptides and peripheral nerve plasticity: neuropathies, neuroprotection and repair. Progress in Brain Research. 100: 223-9. PMID 7938523 DOI: 10.1016/S0079-6123(08)60789-X  0.697
1994 Verhaagen J, Hermens WT, Oestreicher AB, Gispen WH, Rabkin SD, Pfaff DW, Kaplitt MG. Expression of the growth-associated protein B-50/GAP43 via a defective herpes-simplex virus vector results in profound morphological changes in non-neuronal cells. Brain Research. Molecular Brain Research. 26: 26-36. PMID 7854056 DOI: 10.1016/0169-328X(94)90070-1  0.656
1994 Plantinga LC, Schrama LH, Eggen BJ, Gispen WH, Verhaagen J, Lemke G. B-50/GAP-43 mRNA expression in cultured primary Schwann cells is regulated by cyclic AMP. Neuroreport. 5: 2465-8. PMID 7696581 DOI: 10.1097/00001756-199412000-00015  0.597
1994 Duckers H, van Dokkum R, Verhaagen J, Gispen W. A neurotrophic ACTH(4–9) analogue prevents the formation of central demyelinating lesions in CEAE and normalizes central conduction slowing Journal of Neuroimmunology. 54: 164. DOI: 10.1016/0165-5728(94)90333-6  0.531
1993 Ulenkate HJ, Verhaagen J, Plantinga LC, Mercken M, Veldman H, Jennekens FG, Gispen WH, Oestreicher AB. Upregulation of B-50/GAP-43 in Schwann cells at denervated motor endplates and in motoneurons after rat facial nerve crush. Restorative Neurology and Neuroscience. 6: 35-47. PMID 21551729 DOI: 10.3233/Rnn-1993-6104  0.732
1993 Plantinga LC, Verhaagen J, Gispen WH. The expression of B-50/GAP-43 in Schwann cells. Annals of the New York Academy of Sciences. 679: 412-7. PMID 8512206 DOI: 10.1111/j.1749-6632.1993.tb18331.x  0.586
1993 Plantinga LC, Verhaagen J, Edwards PM, Hol EM, Bär PR, Gispen WH. The expression of B-50/GAP-43 in Schwann cells is upregulated in degenerating peripheral nerve stumps following nerve injury. Brain Research. 602: 69-76. PMID 8448659 DOI: 10.1016/0006-8993(93)90243-G  0.722
1993 Hol EM, Hermens WT, Verhaagen J, Gispen WH, Bär PR. alpha MSH but not Org 2766 induces expression of c-fos in cultured rat spinal cord cells. Neuroreport. 4: 651-4. PMID 8394152  0.668
1993 Duckers HJ, Verhaagen J, Gispen WH. A neurotrophic analogue of ACTH4-9 protects against experimental allergic neuritis. Annals of the New York Academy of Sciences. 680: 493-5. PMID 8390175  0.499
1993 Verhaagen J, Zhang Y, Hamers FP, Gispen WH. Elevated expression of B-50 (GAP-43)-mRNA in a subpopulation of olfactory bulb mitral cells following axotomy. Journal of Neuroscience Research. 35: 162-9. PMID 8320748 DOI: 10.1002/jnr.490350206  0.678
1993 Duckers HJ, Verhaagen J, Gispen WH. The neurotrophic analogue of ACTH(4-9), Org 2766, protects against experimental allergic neuritis. Brain : a Journal of Neurology. 116: 1059-75. PMID 8221047  0.6
1992 Ramakers GJ, Verhaagen J, Oestreicher AB, Margolis FL, van Bergen en Henegouwen PM, Gispen WH. Immunolocalization of B-50 (GAP-43) in the mouse olfactory bulb: predominant presence in preterminal axons. Journal of Neurocytology. 21: 853-69. PMID 1469462 DOI: 10.1007/Bf01191683  0.624
1992 Plantinga LC, Verhaagen J, Edwards PM, Schrama LH, Burbach JP, Gispen WH. Expression of the pro-opiomelanocortin gene in dorsal root ganglia, spinal cord and sciatic nerve after sciatic nerve crush in the rat. Brain Research. Molecular Brain Research. 16: 135-42. PMID 1334192 DOI: 10.1016/0169-328X(92)90203-N  0.611
1991 Margolis FL, Verhaagen J, Biffo S, Huang FL, Grillo M. Regulation of gene expression in the olfactory neuroepithelium: a neurogenetic matrix. Progress in Brain Research. 89: 97-122. PMID 1839074 DOI: 10.1016/S0079-6123(08)61718-5  0.351
1990 Gispen WH, Boonstra J, De Graan PN, Jennekens FG, Oestreicher AB, Schotman P, Schrama LH, Verhaagen J, Margolis FL. B-50/GAP-43 in neuronal development and repair. Restorative Neurology and Neuroscience. 1: 237-44. PMID 21551562 DOI: 10.3233/Rnn-1990-13410  0.737
1990 Verhaagen J, Oestreicher AB, Grillo M, Khew-Goodall YS, Gispen WH, Margolis FL. Neuroplasticity in the olfactory system: differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B-50/GAP43 and the olfactory marker protein. Journal of Neuroscience Research. 26: 31-44. PMID 2141653 DOI: 10.1002/Jnr.490260105  0.629
1989 Verhaagen J, Oestreicher AB, Gispen WH, Margolis FL. The expression of the growth associated protein B50/GAP43 in the olfactory system of neonatal and adult rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 683-91. PMID 2918383 DOI: 10.1523/Jneurosci.09-02-00683.1989  0.64
1989 Van der Zee CE, Nielander HB, Vos JP, Lopes da Silva S, Verhaagen J, Oestreicher AB, Schrama LH, Schotman P, Gispen WH. Expression of growth-associated protein B-50 (GAP43) in dorsal root ganglia and sciatic nerve during regenerative sprouting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 3505-12. PMID 2552034 DOI: 10.1523/Jneurosci.09-10-03505.1989  0.654
1989 de Koning P, Verhaagen J, Sloot W, Jennekens FG, Gispen WH. Org.2766 stimulates collateral sprouting in the soleus muscle of the rat following partial denervation. Muscle & Nerve. 12: 353-9. PMID 2542784 DOI: 10.1002/Mus.880120503  0.679
1988 Verhaagen J, Oesteicher AB, Edwards PM, Veldman H, Jennekens FG, Gispen WH. Light- and electron-microscopical study of phosphoprotein B-50 following denervation and reinnervation of the rat soleus muscle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 1759-66. PMID 2966853 DOI: 10.1523/Jneurosci.08-05-01759.1988  0.729
1988 Verhaagen J, Edwards PM, Gispen WH. Damaged rat peripheral nerves do not contain detectable amounts of alpha-MSH. Journal of Neuroscience Research. 19: 14-8. PMID 2830414 DOI: 10.1002/jnr.490190103  0.568
1987 Gispen WH, De Koning P, Kuiters RR, Van der Zee CE, Verhaagen J. On the neurotrophic action of melanocortins. Progress in Brain Research. 72: 319-31. PMID 3039580 DOI: 10.1016/S0079-6123(08)60218-6  0.5
1987 Verhaagen J, Edwards PM, Jennekens FG, Schotman P, Gispen WH. Early effect of an ACTH4-9 analog (Org.2766) on regenerative sprouting demonstrated by the use of neurofilament-binding antibodies isolated from a serum raised by alpha-MSH immunization. Brain Research. 404: 142-50. PMID 3032330 DOI: 10.1016/0006-8993(87)91365-5  0.703
1987 Verhaagen J, Edwards PM, Jennekens FG, Gispen WH. Pharmacological aspects of the influence of melanocortins on the formation of regenerative peripheral nerve sprouts. Peptides. 8: 581-4. PMID 2819831 DOI: 10.1016/0196-9781(87)90028-3  0.679
1986 Verhaagen J, Edwards PM, Jennekens FG, Schotman P, Gispen WH. Alpha-melanocyte-stimulating hormone stimulates the outgrowth of myelinated nerve fibers after peripheral nerve crush. Experimental Neurology. 92: 451-4. PMID 3956675 DOI: 10.1016/0014-4886(86)90098-1  0.7
1986 Verhaagen J, van Hooff CO, Edwards PM, De Graan PN, Oestreicher AB, Schotman P, Jennekens FG, Gispen WH. The kinase C substrate protein B-50 and axonal regeneration. Brain Research Bulletin. 17: 737-41. PMID 2948616 DOI: 10.1016/0361-9230(86)90084-5  0.725
1986 Verhaagen J, Edwards PM, Schotman P, Jennekens FG, Gispen WH. Characterization of epitopes shared by alpha-melanocyte-stimulating hormone (alpha-MSH) and the 150-kD neurofilament protein (NF150): relationship to neurotrophic sequences. Journal of Neuroscience Research. 16: 589-600. PMID 2432275 DOI: 10.1002/jnr.490160402  0.648
1985 Edwards PM, Verhaagen J, Spierings T, Schotman P, Jennekens FG, Gispen WH. The effect of ACTH4-10 on protein synthesis, actin and tubulin during regeneration. Brain Research Bulletin. 15: 267-72. PMID 2996720 DOI: 10.1016/0361-9230(85)90149-2  0.554
1984 Edwards PM, Van der Zee CE, Verhaagen J, Schotman P, Jennekens FG, Gispen WH. Evidence that the neurotrophic actions of alpha-MSH may derive from its ability to mimick the actions of a peptide formed in degenerating nerve stumps. Journal of the Neurological Sciences. 64: 333-40. PMID 6432963 DOI: 10.1016/0022-510X(84)90181-3  0.703
Low-probability matches (unlikely to be authored by this person)
2020 Eggers R, de Winter F, Tannemaat MR, Malessy MJA, Verhaagen J. GDNF Gene Therapy to Repair the Injured Peripheral Nerve. Frontiers in Bioengineering and Biotechnology. 8: 583184. PMID 33251197 DOI: 10.3389/fbioe.2020.583184  0.296
2016 Fagoe ND, Attwell CL, Eggers R, Tuinenbreijer L, Kouwenhoven D, Verhaagen J, Mason MR. Evaluation of Five Tests for Sensitivity to Functional Deficits following Cervical or Thoracic Dorsal Column Transection in the Rat. Plos One. 11: e0150141. PMID 26934672 DOI: 10.1371/Journal.Pone.0150141  0.293
2015 James ND, Shea J, Muir EM, Verhaagen J, Schneider BL, Bradbury EJ. Chondroitinase gene therapy improves upper limb function following cervical contusion injury. Experimental Neurology. 271: 131-5. PMID 26044197 DOI: 10.1016/J.Expneurol.2015.05.022  0.293
2007 Hendriks WT, Eggers R, Carlstedt TP, Zaldumbide A, Tannemaat MR, Fallaux FJ, Hoeben RC, Boer GJ, Verhaagen J. Lentiviral vector-mediated reporter gene expression in avulsed spinal ventral root is short-term, but is prolonged using an immune "stealth" transgene. Restorative Neurology and Neuroscience. 25: 585-99. PMID 18418947  0.289
2001 Boer GJ, van Esseveldt KE, Dijkhuizen PA, Hermens WT, te Beek ET, van Heerikhuize JJ, Poldervaart HA, Verhaagen J. Adenoviral vector-mediated expression of neurotrophin-3 increases neuronal survival in suprachiasmatic nucleus grafts. Experimental Neurology. 169: 364-75. PMID 11358449 DOI: 10.1006/Exnr.2001.7683  0.287
1990 Verhaagen J, Greer CA, Margolis FL. B-50/GAP43 Gene Expression in the Rat Olfactory System During Postnatal Development and Aging. The European Journal of Neuroscience. 2: 397-407. PMID 12106027 DOI: 10.1111/J.1460-9568.1990.Tb00432.X  0.286
2004 Blits B, Carlstedt TP, Ruitenberg MJ, de Winter F, Hermens WT, Dijkhuizen PA, Claasens JW, Eggers R, van der Sluis R, Tenenbaum L, Boer GJ, Verhaagen J. Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor. Experimental Neurology. 189: 303-16. PMID 15380481 DOI: 10.1016/j.expneurol.2004.05.014  0.286
2004 Ruitenberg MJ, Blits B, Dijkhuizen PA, te Beek ET, Bakker A, van Heerikhuize JJ, Pool CW, Hermens WT, Boer GJ, Verhaagen J. Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury. Neurobiology of Disease. 15: 394-406. PMID 15006710 DOI: 10.1016/j.nbd.2003.11.018  0.285
2005 Ruitenberg MJ, Levison DB, Lee SV, Verhaagen J, Harvey AR, Plant GW. NT-3 expression from engineered olfactory ensheathing glia promotes spinal sparing and regeneration. Brain : a Journal of Neurology. 128: 839-53. PMID 15716305 DOI: 10.1093/brain/awh424  0.283
2010 van Strien ME, Mercier D, Drukarch B, Brevé JJ, Poole S, Binnekade R, Bol JG, Blits B, Verhaagen J, van Dam AM. Anti-inflammatory effect by lentiviral-mediated overexpression of IL-10 or IL-1 receptor antagonist in rat glial cells and macrophages. Gene Therapy. 17: 662-71. PMID 20182518 DOI: 10.1038/Gt.2010.8  0.283
2019 Muir E, De Winter F, Verhaagen J, Fawcett J. Recent advances in the therapeutic uses of chondroitinase ABC. Experimental Neurology. 321: 113032. PMID 31398353 DOI: 10.1016/J.Expneurol.2019.113032  0.283
2010 Zaldumbide A, Weening S, Cramer SJ, Rabelink MJ, Verhaagen J, Hoeben RC. A potentially immunologically inert derivative of the reverse tetracycline-controlled transactivator. Biotechnology Letters. 32: 749-54. PMID 20155386 DOI: 10.1007/S10529-010-0218-8  0.279
1990 Biffo S, Verhaagen J, Schrama LH, Schotman P, Danho W, Margolis FL. B-50/GAP43 Expression Correlates with Process Outgrowth in the Embryonic Mouse Nervous System. The European Journal of Neuroscience. 2: 487-499. PMID 12106019 DOI: 10.1111/J.1460-9568.1990.Tb00440.X  0.279
1990 Biffo S, Verhaagen J, Schrama LH, Schotman P, Danho W, Margolis FL. B-50/GAP43 expression correlates with process outgrowth in the embryonic mouse nervous system European Journal of Neuroscience. 2: 487-499. DOI: 10.1111/j.1460-9568.1990.tb00440.x  0.279
2014 Alves CH, Pellissier LP, Vos RM, Garcia Garrido M, Sothilingam V, Seide C, Beck SC, Klooster J, Furukawa T, Flannery JG, Verhaagen J, Seeliger MW, Wijnholds J. Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa. Human Molecular Genetics. 23: 3384-401. PMID 24493795 DOI: 10.1093/Hmg/Ddu048  0.278
2022 Mason MRJ, van Erp S, Wolzak K, Behrens A, Raivich G, Verhaagen J. Erratum to: The Jun-dependent axon regeneration gene program: Jun promotes regeneration over plasticity. Human Molecular Genetics. PMID 35166771 DOI: 10.1093/hmg/ddac044  0.271
2023 Nieuwenhuis B, Laperrousaz E, Tribble JR, Verhaagen J, Fawcett JW, Martin KR, Williams PA, Osborne A. Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters. Gene Therapy. PMID 36635457 DOI: 10.1038/s41434-022-00380-z  0.269
2010 Bossers K, Ylstra B, Brakenhoff RH, Smeets SJ, Verhaagen J, van de Wiel MA. Intensity-based analysis of dual-color gene expression data as an alternative to ratio-based analysis to enhance reproducibility. Bmc Genomics. 11: 112. PMID 20163706 DOI: 10.1186/1471-2164-11-112  0.266
2002 Verwer RW, Hermens WT, ter Brake O, Verhaagen J, Swaab DF. Life after death? Neurology. 59: 1355. PMID 12427883  0.266
2013 Alves CH, Bossers K, Vos RM, Essing AH, Swagemakers S, van der Spek PJ, Verhaagen J, Wijnholds J. Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background. Plos One. 8: e82532. PMID 24324803 DOI: 10.1371/Journal.Pone.0082532  0.26
2018 Maldonado-Lasunción I, Verhaagen J, Oudega M. Mesenchymal Stem Cell-Macrophage Choreography Supporting Spinal Cord Repair. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 29728851 DOI: 10.1007/S13311-018-0629-0  0.256
2013 Petrova IM, Lahaye LL, Martiáñez T, de Jong AW, Malessy MJ, Verhaagen J, Noordermeer JN, Fradkin LG. Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B. Molecular and Cellular Biology. 33: 4116-27. PMID 23979591 DOI: 10.1128/Mcb.00169-13  0.25
2009 Verhaagen J. Neurotherapy: Progress in Restorative Neuroscience and Neurology. Preface. Progress in Brain Research. 175: ix. PMID 19660644 DOI: 10.1016/S0079-6123(09)17536-2  0.242
2011 Roet KC, Bossers K, Franssen EH, Ruitenberg MJ, Verhaagen J. A meta-analysis of microarray-based gene expression studies of olfactory bulb-derived olfactory ensheathing cells. Experimental Neurology. 229: 10-45. PMID 21396936 DOI: 10.1016/j.expneurol.2011.03.001  0.242
2004 Kas MJ, Tiesjema B, van Dijk G, Garner KM, Barsh GS, ter Brake O, Verhaagen J, Adan RA. Induction of brain-region-specific forms of obesity by agouti. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10176-81. PMID 15537888 DOI: 10.1523/Jneurosci.3442-04.2004  0.241
2015 Fagoe ND, Eggers R, Verhaagen J, Mason MRJ. Gene delivery to neurons of the dorsal root ganglia using adeno-associated viral vectors Neuromethods. 98: 175-189. DOI: 10.1007/978-1-4939-2306-9_7  0.24
1989 Verhaagen J, Boonstra A, De Graan P, Oestreicher A, Schotman P, Schrama L, Margolis F, Gispen W. B-50/GAP43 in neuronal differentiation and plasticity Cell Differentiation and Development. 27: 173. DOI: 10.1016/0922-3371(89)90527-3  0.236
2021 Carulli D, de Winter F, Verhaagen J. Semaphorins in Adult Nervous System Plasticity and Disease. Frontiers in Synaptic Neuroscience. 13: 672891. PMID 34045951 DOI: 10.3389/fnsyn.2021.672891  0.236
2004 de Winter F, Cui Q, Symons N, Verhaagen J, Harvey AR. Expression of class-3 semaphorins and their receptors in the neonatal and adult rat retina. Investigative Ophthalmology & Visual Science. 45: 4554-62. PMID 15557467 DOI: 10.1167/iovs.04-0173  0.233
1997 Verhaagen J, Schrama LH. The application of gene transfer technology in neurobiology Journal of Neuroscience Methods. 71: vii. DOI: 10.1016/S0165-0270(96)00120-3  0.231
2012 Sharma A, Verhaagen J, Harvey AR. Receptor complexes for each of the Class 3 Semaphorins. Frontiers in Cellular Neuroscience. 6: 28. PMID 22783168 DOI: 10.3389/Fncel.2012.00028  0.23
2002 Ruitenberg MJ, Plant GW, Christensen CL, Blits B, Niclou SP, Harvey AR, Boer GJ, Verhaagen J. Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord. Gene Therapy. 9: 135-46. PMID 11857072 DOI: 10.1038/sj.gt.3301626  0.216
2018 Verhaagen J, Hobo B, Ehlert EME, Eggers R, Korecka JA, Hoyng SA, Attwell CL, Harvey AR, Mason MRJ. Small Scale Production of Recombinant Adeno-Associated Viral Vectors for Gene Delivery to the Nervous System. Methods in Molecular Biology (Clifton, N.J.). 1715: 3-17. PMID 29188502 DOI: 10.1007/978-1-4939-7522-8_1  0.216
2018 Verhaagen J, Hobo B, Ehlert EME, Eggers R, Korecka JA, Hoyng SA, Attwell CL, Harvey AR, Mason MRJ. Small Scale Production of Recombinant Adeno-Associated Viral Vectors for Gene Delivery to the Nervous System. Methods in Molecular Biology (Clifton, N.J.). 1715: 3-17. PMID 29188502 DOI: 10.1007/978-1-4939-7522-8_1  0.216
2002 Eaton MJ, Blits B, Ruitenberg MJ, Verhaagen J, Oudega M. Amelioration of chronic neuropathic pain after partial nerve injury by adeno-associated viral (AAV) vector-mediated over-expression of BDNF in the rat spinal cord. Gene Therapy. 9: 1387-95. PMID 12365004 DOI: 10.1038/sj.gt.3301814  0.211
2000 Tenenbaum L, Jurysta F, Stathopoulos A, Puschban Z, Melas C, Hermens WT, Verhaagen J, Pichon B, Velu T, Levivier M. Tropism of AAV-2 vectors for neurons of the globus pallidus. Neuroreport. 11: 2277-83. PMID 10923685  0.211
2002 Ruitenberg MJ, Eggers R, Boer GJ, Verhaagen J. Adeno-associated viral vectors as agents for gene delivery: application in disorders and trauma of the central nervous system. Methods (San Diego, Calif.). 28: 182-94. PMID 12413416 DOI: 10.1016/S1046-2023(02)00222-0  0.208
2013 Fitzsimons CP, van Hooijdonk LW, Schouten M, Zalachoras I, Brinks V, Zheng T, Schouten TG, Saaltink DJ, Dijkmans T, Steindler DA, Verhaagen J, Verbeek FJ, Lucassen PJ, de Kloet ER, Meijer OC, et al. Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior. Molecular Psychiatry. 18: 993-1005. PMID 22925833 DOI: 10.1038/Mp.2012.123  0.207
2014 Roet KCD, Wirz KTS, Franssen EHP, Verhaagen J. Validation of NRP1 and NRP2 knockdown effects on SC cluster formation. Plos One. DOI: 10.1371/Journal.Pone.0109401.G003  0.201
1995 Eggen BJL, Kleijnen MF, Verhaagen J, Schrama LH. Neuron-specificity of rat B-50/GAP-43 promoter P2 in P19-EC cells Neuroscience Research Communications. 17: 19-26.  0.195
1999 Hassink GC, van Esseveldt KE, Dijkhuizen PA, Verhaagen J, Boer GJ. Ontogeny of neurotrophin receptor trkC expression in the rat forebrain and anterior hypothalamus with emphasis on the suprachiasmatic nucleus. Neuroscience. 92: 705-12. PMID 10408619 DOI: 10.1016/S0306-4522(99)00007-X  0.185
1999 Pasterkamp RJ, Ruitenberg MJ, Verhaagen J. Semaphorins and their receptors in olfactory axon guidance. Cellular and Molecular Biology (Noisy-Le-Grand, France). 45: 763-79. PMID 10541474  0.183
2009 Hellström M, Ruitenberg MJ, Pollett MA, Ehlert EM, Twisk J, Verhaagen J, Harvey AR. Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection. Gene Therapy. 16: 521-32. PMID 19092858 DOI: 10.1038/gt.2008.178  0.182
2021 Carulli D, Verhaagen J. An Extracellular Perspective on CNS Maturation: Perineuronal Nets and the Control of Plasticity. International Journal of Molecular Sciences. 22. PMID 33670945 DOI: 10.3390/ijms22052434  0.173
2006 Hendriks WT, Eggers R, Ruitenberg MJ, Blits B, Hamers FP, Verhaagen J, Boer GJ. Profound differences in spontaneous long-term functional recovery after defined spinal tract lesions in the rat. Journal of Neurotrauma. 23: 18-35. PMID 16430370 DOI: 10.1089/neu.2006.23.18  0.167
2021 Maldonado-Lasunción I, O'Neill N, Umland O, Verhaagen J, Oudega M. Macrophage-Derived Inflammation Induces a Transcriptome Makeover in Mesenchymal Stromal Cells Enhancing Their Potential for Tissue Repair. International Journal of Molecular Sciences. 22. PMID 33466704 DOI: 10.3390/ijms22020781  0.155
2021 Chalaki M, Cruz LJ, van Neerven SGA, Verhaagen J, Dahan A, Malessy MJA. Molecular Changes in the Dorsal Root Ganglion during the Late Phase of Peripheral Nerve Injury-induced Pain in Rodents: A Systematic Review. Anesthesiology. PMID 34965284 DOI: 10.1097/ALN.0000000000004092  0.151
2022 Francos-Quijorna I, Sánchez-Petidier M, Burnside ER, Badea SR, Torres-Espin A, Marshall L, de Winter F, Verhaagen J, Moreno-Manzano V, Bradbury EJ. Chondroitin sulfate proteoglycans prevent immune cell phenotypic conversion and inflammation resolution via TLR4 in rodent models of spinal cord injury. Nature Communications. 13: 2933. PMID 35614038 DOI: 10.1038/s41467-022-30467-5  0.149
1985 Zwiers H, Verhaagen J, van Dongen CJ, de Graan PN, Gispen WH. Resolution of rat brain synaptic phosphoprotein B-50 into multiple forms by two-dimensional electrophoresis: evidence for multisite phosphorylation. Journal of Neurochemistry. 44: 1083-90. PMID 3156211  0.138
2021 Maldonado-Lasunción I, Haggerty AE, Okuda A, Mihara T, de la Oliva N, Verhaagen J, Oudega M. The Effect of Inflammatory Priming on the Therapeutic Potential of Mesenchymal Stromal Cells for Spinal Cord Repair. Cells. 10. PMID 34070547 DOI: 10.3390/cells10061316  0.13
2003 Eisch AJ, Bolaños CA, de Wit J, Simonak RD, Pudiak CM, Barrot M, Verhaagen J, Nestler EJ. Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression. Biological Psychiatry. 54: 994-1005. PMID 14625141 DOI: 10.1016/j.biopsych.2003.08.003  0.127
2015 James ND, Shea J, Muir EM, Verhaagen J, Schneider BL, Bradbury EJ. Chondroitinase gene therapy improves upper limb function following cervical contusion injury Experimental Neurology. 271: 131-135. DOI: 10.1016/j.expneurol.2015.05.022  0.118
2006 Ruitenberg MJ, Hendriks WTJ, Boer GJ, Verhaagen J. Gene Therapy for Spinal Cord Injury Gene Therapy of the Central Nervous System: From Bench to Bedside. 273-288. DOI: 10.1016/B978-012397632-1/50022-8  0.113
1994 Duckers HJ, Verhaagen J, De Bruijn E, Gispen WH. Effective use of a neurotrophic ACTH4-9 analogue in the treatment of a peripheral demyelinating syndrome (experimental allergic neuritis): An intervention study Brain. 117: 365-374.  0.101
1999 Dijkhuizen PA, Verhaagen J. The use of neurotrophic factors to treat spinal cord injury: Advantages and disadvantages of different delivery methods Neuroscience Research Communications. 24: 1-10. DOI: 10.1002/(SICI)1520-6769(199901/02)24:1<1::AID-NRC1>3.0.CO;2-7  0.1
2006 Oudega M, Blits B, Verhaagen J, Boer GJ. Experimental strategies to repair the injured spinal cord Journal of Neurotrauma. 23: ii-iii.  0.086
2021 Crivelli SM, Luo Q, Stevens JAA, Giovagnoni C, van Kruining D, Bode G, den Hoedt S, Hobo B, Scheithauer AL, Walter J, Mulder MT, Exley C, Mold M, Mielke MM, De Vries HE, ... ... Verhaagen J, et al. CERT reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease. Alzheimer's Research & Therapy. 13: 45. PMID 33597019 DOI: 10.1186/s13195-021-00780-0  0.081
1994 Verhaagen J. Olvfaction in a nutshell.The cell biology of olfaction(1992). By ALBERTI. FARBMAN. Cambridge University Press, Cambridge, pp. xii+280. £35/$59.95. ISBN 0 521 36438 8 Bioessays. 16: 857-858. DOI: 10.1002/BIES.950161115  0.072
2021 Yang S, Gigout S, Molinaro A, Naito-Matsui Y, Hilton S, Foscarin S, Nieuwenhuis B, Tan CL, Verhaagen J, Pizzorusso T, Saksida LM, Bussey TM, Kitagawa H, Kwok JCF, Fawcett JW. Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing. Molecular Psychiatry. PMID 34272488 DOI: 10.1038/s41380-021-01208-9  0.068
2021 Yang S, Gigout S, Molinaro A, Naito-Matsui Y, Hilton S, Foscarin S, Nieuwenhuis B, Tan CL, Verhaagen J, Pizzorusso T, Saksida LM, Bussey TM, Kitagawa H, Kwok JCF, Fawcett JW. Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing. Molecular Psychiatry. PMID 34272488 DOI: 10.1038/s41380-021-01208-9  0.068
2007 Adams M, Carlstedt T, Cavanagh J, Lemon RN, McKernan R, Priestley JV, Raisman G, Verhaagen J. International spinal research trust research strategy. III: A discussion document. Spinal Cord. 45: 2-14. PMID 16883299 DOI: 10.1038/sj.sc.3101963  0.054
2015 Bo X, Verhaagen J. Preface Neuromethods. 98: 7. DOI: 10.1016/B978-0-444-52137-8.09990-3  0.01
2007 Janssens PMW, Ruinemans-Koerts J, Telting D, Verhaagen J, Willekens FLA, Gerritsen GWJ. Costs and benefits of quality management and accreditation in the clinical laboratory: A management account | Kosten en baten van kwaliteitsmanagement en accreditatie in een klinischchemisch laboratorium Nederlands Tijdschrift Voor Klinische Chemie En Laboratoriumgeneeskunde. 32: 237-243.  0.01
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