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Beshay N. Zordoky, Ph.D. - Publications

Affiliations: 
2012 University of Alberta, Edmonton, Alberta, Canada 
Area:
Pharmaceutical Chemistry, Physiology Biology
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Abdelgawad IY, George B, Grant MKO, Huang Y, Shan Y, Huang RS, Zordoky BN. Sex-related differences in delayed doxorubicin-induced cardiac dysfunction in C57BL/6 mice. Archives of Toxicology. PMID 38244039 DOI: 10.1007/s00204-023-03678-y  0.358
2022 Agostinucci K, Grant MKO, Seelig D, Yücel D, van Berlo J, Bartolomucci A, Dyck JRB, Zordoky BN. Divergent Cardiac Effects of Angiotensin II and Isoproterenol Following Juvenile Exposure to Doxorubicin. Frontiers in Cardiovascular Medicine. 9: 742193. PMID 35402534 DOI: 10.3389/fcvm.2022.742193  0.332
2020 Grant MKO, Abdelgawad IY, Lewis CA, Seelig D, Zordoky BN. Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction. Plos One. 15: e0232507. PMID 32645007 DOI: 10.1371/Journal.Pone.0232507  0.418
2020 Grant MKO, Abdelgawad IY, Lewis CA, Zordoky BN. Sexual Dimorphism in Doxorubicin-induced Systemic Inflammation: Implications for Hepatic Cytochrome P450 Regulation. International Journal of Molecular Sciences. 21. PMID 32074957 DOI: 10.3390/Ijms21041279  0.4
2019 Grant MKO, Seelig DM, Sharkey LC, Choi WSV, Abdelgawad IY, Zordoky BN. Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice. Plos One. 14: e0212486. PMID 30785938 DOI: 10.1371/Journal.Pone.0212486  0.389
2018 Matsumura N, Zordoky BN, Robertson IM, Hamza SM, Parajuli N, Soltys CM, Beker DL, Grant MK, Razzoli M, Bartolomucci A, Dyck JRB. Co-administration of resveratrol with doxorubicin in young mice attenuates detrimental late-occurring cardiovascular changes. Cardiovascular Research. PMID 29566148 DOI: 10.1093/Cvr/Cvy064  0.328
2017 Grant MK, Seelig DM, Sharkey LC, Zordoky BN. Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice. Biology of Sex Differences. 8: 1. PMID 28078076 DOI: 10.1186/S13293-016-0124-4  0.526
2015 Sung MM, Zordoky BN, Bujak AL, Lally JS, Fung D, Young ME, Horman S, Miller EJ, Light PE, Kemp BE, Steinberg GR, Dyck JR. AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism. Cardiovascular Research. 107: 235-45. PMID 26023060 DOI: 10.1093/Cvr/Cvv166  0.44
2015 Zordoky BN, Sung MM, Ezekowitz J, Mandal R, Han B, Bjorndahl TC, Bouatra S, Anderson T, Oudit GY, Wishart DS, Dyck JR. Metabolomic fingerprint of heart failure with preserved ejection fraction. Plos One. 10: e0124844. PMID 26010610 DOI: 10.1371/Journal.Pone.0124844  0.369
2013 Dolinsky VW, Chakrabarti S, Pereira TJ, Oka T, Levasseur J, Beker D, Zordoky BN, Morton JS, Nagendran J, Lopaschuk GD, Davidge ST, Dyck JR. Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice. Biochimica Et Biophysica Acta. 1832: 1723-33. PMID 23707558 DOI: 10.1016/J.Bbadis.2013.05.018  0.378
2013 Nagendran J, Kienesberger PC, Pulinilkunnil T, Zordoky BN, Sung MM, Kim T, Young ME, Dyck JR. Cardiomyocyte specific adipose triglyceride lipase overexpression prevents doxorubicin induced cardiac dysfunction in female mice. Heart (British Cardiac Society). 99: 1041-7. PMID 23704323 DOI: 10.1136/Heartjnl-2013-303843  0.565
2013 Dolinsky VW, Rogan KJ, Sung MM, Zordoky BN, Haykowsky MJ, Young ME, Jones LW, Dyck JR. Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice. American Journal of Physiology. Endocrinology and Metabolism. 305: E243-53. PMID 23695218 DOI: 10.1152/Ajpendo.00044.2013  0.369
2013 Alsaad AM, Zordoky BN, Tse MM, El-Kadi AO. Role of cytochrome P450-mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy. Drug Metabolism Reviews. 45: 173-95. PMID 23600686 DOI: 10.3109/03602532.2012.754460  0.6
2013 Anwar-Mohamed A, El-Sherbeni A, Kim SH, Elshenawy OH, Althurwi HN, Zordoky BN, El-Kadi AO. Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 43: 719-29. PMID 23409951 DOI: 10.3109/00498254.2012.754113  0.623
2013 Althurwi HN, Tse MM, Abdelhamid G, Zordoky BN, Hammock BD, El-Kadi AO. Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy. British Journal of Pharmacology. 168: 1794-807. PMID 23176298 DOI: 10.1111/Bph.12066  0.648
2013 El-Sherbeni AA, Aboutabl ME, Zordoky BN, Anwar-Mohamed A, El-Kadi AO. Determination of the dominant arachidonic acid cytochrome p450 monooxygenases in rat heart, lung, kidney, and liver: protein expression and metabolite kinetics. The Aaps Journal. 15: 112-22. PMID 23139020 DOI: 10.1208/S12248-012-9425-7  0.782
2013 Chaudhary KR, Zordoky BN, Edin ML, Alsaleh N, El-Kadi AO, Zeldin DC, Seubert JM. Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice. Prostaglandins & Other Lipid Mediators. 104: 8-17. PMID 22922020 DOI: 10.1016/j.prostaglandins.2012.08.001  0.53
2013 Dolinsky VW, Chakrabarti S, Pereira TJ, Oka T, Zordoky BN, Morton JS, Nagendran J, Opaschuk GD, Davidge ST, Dyck JR. Resveratrol Prevents Hypertension and Cardiac Hypertrophy in Hypertensive Rodents Canadian Journal of Diabetes. 37: S23. DOI: 10.1016/J.Jcjd.2013.08.070  0.332
2012 Alsaad AM, Zordoky BN, El-Sherbeni AA, El-Kadi AO. Chronic doxorubicin cardiotoxicity modulates cardiac cytochrome P450-mediated arachidonic acid metabolism in rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 2126-35. PMID 22867862 DOI: 10.1124/dmd.112.046631  0.741
2012 Anwar-Mohamed A, El-Sherbeni AA, Kim SH, Althurwi HN, Zordoky BN, El-Kadi AO. Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 42: 1235-47. PMID 22680237 DOI: 10.3109/00498254.2012.693971  0.721
2011 Zordoky BN, Anwar-Mohamed A, Aboutabl ME, El-Kadi AO. Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1440-50. PMID 21571947 DOI: 10.1124/Dmd.111.039123  0.798
2011 Aboutabl ME, Zordoky BN, Hammock BD, El-Kadi AO. Inhibition of soluble epoxide hydrolase confers cardioprotection and prevents cardiac cytochrome P450 induction by benzo(a)pyrene. Journal of Cardiovascular Pharmacology. 57: 273-81. PMID 21383588 DOI: 10.1097/Fjc.0B013E3182055Baf  0.788
2010 Zordoky BN, El-Kadi AO. Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases. Pharmacology & Therapeutics. 125: 446-63. PMID 20093140 DOI: 10.1016/j.pharmthera.2009.12.002  0.62
2010 Anwar-mohamed A, Zordoky BN, Aboutabl ME, El-Kadi AO. Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation. Pharmacological Research. 61: 410-8. PMID 20045729 DOI: 10.1016/J.Phrs.2009.12.015  0.807
2010 Zordoky BN, El-Kadi AO. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism. Toxicology in Vitro : An International Journal Published in Association With Bibra. 24: 863-71. PMID 19969063 DOI: 10.1016/j.tiv.2009.12.002  0.583
2010 Zordoky BN, Anwar-Mohamed A, Aboutabl ME, El-Kadi AO. Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats. Toxicology and Applied Pharmacology. 242: 38-46. PMID 19796650 DOI: 10.1016/J.Taap.2009.09.012  0.806
2010 Zordoky B, El-Kadi A. Acute Doxorubicin Toxicity Differentially Alters Cytochrome P450 Expression in the Kidney and Liver of Male Sprague Dawley Rats Free Radical Biology and Medicine. 49: S75. DOI: 10.1016/J.Freeradbiomed.2010.10.187  0.657
2009 Aboutabl ME, Zordoky BN, El-Kadi AO. 3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats. British Journal of Pharmacology. 158: 1808-19. PMID 19889059 DOI: 10.1111/J.1476-5381.2009.00461.X  0.79
2009 Zordoky BN, El-Kadi AO. Role of NF-kappaB in the regulation of cytochrome P450 enzymes. Current Drug Metabolism. 10: 164-78. PMID 19275551 DOI: 10.2174/138920009787522151  0.547
2008 Zordoky BN, Aboutabl ME, El-Kadi AO. Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2277-86. PMID 18725507 DOI: 10.1124/Dmd.108.023077  0.816
2008 Zordoky BN, El-Kadi AO. Induction of several cytochrome P450 genes by doxorubicin in H9c2 cells. Vascular Pharmacology. 49: 166-72. PMID 18707023 DOI: 10.1016/j.vph.2008.07.004  0.612
2008 Zordoky BN, El-Kadi AO. Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure. Current Drug Metabolism. 9: 122-8. PMID 18288954  0.646
2007 Zordoky BN, El-Kadi AO. H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart. Journal of Pharmacological and Toxicological Methods. 56: 317-22. PMID 17662623 DOI: 10.1016/j.vascn.2007.06.001  0.569
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