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Yuansheng Yang, Ph.D. - Publications

Affiliations: 
2005 Vanderbilt University, Nashville, TN 
Area:
Chemical Engineering
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sim KH, Liu LC, Tan HT, Tan K, Ng D, Zhang W, Yang Y, Tate S, Bi X. A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins. Scientific Data. 7: 263. PMID 32782267 DOI: 10.1038/S41597-020-00594-Z  0.362
2019 Xu N, Ou J, Si Y, Goh KY, Flanigan DD, Han X, Yang Y, Yang S, Zhou L, Liu X(. Proteomics insight into the production of monoclonal antibody Biochemical Engineering Journal. 145: 177-185. DOI: 10.1016/J.Bej.2019.02.022  0.467
2018 Yeo JHM, Mariati, Yang Y. An IRES-Mediated Tricistronic Vector for Efficient Generation of Stable, High-Level Monoclonal Antibody Producing CHO DG44 Cell Lines. Methods in Molecular Biology (Clifton, N.J.). 1827: 335-349. PMID 30196505 DOI: 10.1007/978-1-4939-8648-4_17  0.373
2018 Hong JK, Nargund S, Lakshmanan M, Kyriakopoulos S, Kim DY, Ang KS, Leong D, Yang Y, Lee DY. Comparative phenotypic analysis of CHO clones and culture media for lactate shift. Journal of Biotechnology. PMID 30076878 DOI: 10.1016/J.Jbiotec.2018.07.042  0.45
2018 Tan HL, Yong C, Tan BZ, Fong WJ, Padmanabhan J, Chin A, Ding V, Lau A, Zheng L, Bi X, Yang Y, Choo A. Conservation of oncofetal antigens on human embryonic stem cells enables discovery of monoclonal antibodies against cancer. Scientific Reports. 8: 11608. PMID 30072783 DOI: 10.1038/S41598-018-30070-Z  0.316
2018 Cua S, Tan HL, Fong WJ, Chin A, Lau A, Ding V, Song Z, Yang Y, Choo A. Targeting of embryonic annexin A2 expressed on ovarian and breast cancer by the novel monoclonal antibody 2448. Oncotarget. 9: 13206-13221. PMID 29568351 DOI: 10.18632/Oncotarget.24152  0.325
2017 Yeo JHM, Ho SCL, Mariati M, Koh E, Tay SJ, Woen S, Zhang P, Yang Y. Optimized Selection Marker and CHO Host Cell Combinations for Generating High Monoclonal Antibody Producing Cell Lines. Biotechnology Journal. PMID 29090854 DOI: 10.1002/Biot.201700175  0.429
2017 Soo BPC, Tay J, Ng S, Ho SCL, Yang Y, Chao SH. Correlation Between Expression of Recombinant Proteins and Abundance of H3K4Me3 on the Enhancer of Human Cytomegalovirus Major Immediate-Early Promoter. Molecular Biotechnology. PMID 28664508 DOI: 10.1007/S12033-017-0019-6  0.38
2017 Yusufi FNK, Lakshmanan M, Ho YS, Loo BLW, Ariyaratne P, Yang Y, Ng SK, Tan TRM, Yeo HC, Lim HL, Ng SW, Hiu AP, Chow CP, Wan C, Chen S, et al. Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line. Cell Systems. 4: 530-542.e6. PMID 28544881 DOI: 10.1016/J.Cels.2017.04.009  0.444
2016 Chen Q, Toh P, Hoi A, Xian M, Peng X, Yang Y, Zhang H, Nian R, Zhang W. [Improved protein-A chromatography for monoclonal antibody purification]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 32: 807-818. PMID 29019189 DOI: 10.13345/J.Cjb.160137  0.38
2016 Ho SC, Koh EY, Soo BP, Mariati, Chao SH, Yang Y. Evaluating the use of a CpG free promoter for long-term recombinant protein expression stability in Chinese hamster ovary cells. Bmc Biotechnology. 16: 71. PMID 27756290 DOI: 10.1186/S12896-016-0300-Y  0.373
2016 Ho SC, Nian R, Woen S, Chng J, Zhang P, Yang Y. Impact of hydrolysates on monoclonal antibody productivity, purification and quality in Chinese hamster ovary cells. Journal of Bioscience and Bioengineering. PMID 27067279 DOI: 10.1016/J.Jbiosc.2016.03.003  0.45
2016 Zhang P, Woen S, Wang T, Liau B, Zhao S, Chen C, Yang Y, Song Z, Wormald MR, Yu C, Rudd PM. Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs. Drug Discovery Today. PMID 26821133 DOI: 10.1016/J.Drudis.2016.01.006  0.35
2015 Chan KF, Shahreel W, Wan C, Teo G, Hayati N, Tay SJ, Tong WH, Yang Y, Rudd PM, Zhang P, Song Z. Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies. Biotechnology Journal. PMID 26471004 DOI: 10.1002/Biot.201500331  0.399
2015 Gagnon P, Nian R, Yang Y, Yang Q, Lim CL. Non-immunospecific association of immunoglobulin G with chromatin during elution from protein A inflates host contamination, aggregate content, and antibody loss. Journal of Chromatography. A. PMID 26187767 DOI: 10.1016/J.Chroma.2015.07.017  0.302
2015 Tan L, Yeo V, Yang Y, Gagnon P. Characterization of DNA in cell culture supernatant by fluorescence-detection size-exclusion chromatography. Analytical and Bioanalytical Chemistry. 407: 4173-81. PMID 25821116 DOI: 10.1007/S00216-015-8639-9  0.371
2015 Ho SC, Wang T, Song Z, Yang Y. IgG Aggregation Mechanism for CHO Cell Lines Expressing Excess Heavy Chains. Molecular Biotechnology. 57: 625-34. PMID 25744439 DOI: 10.1007/S12033-015-9852-7  0.409
2015 Chng J, Wang T, Nian R, Lau A, Hoi KM, Ho SC, Gagnon P, Bi X, Yang Y. Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells. Mabs. 7: 403-12. PMID 25621616 DOI: 10.1080/19420862.2015.1008351  0.331
2015 Ho SC, Mariati, Yeo JH, Fang SG, Yang Y. Impact of using different promoters and matrix attachment regions on recombinant protein expression level and stability in stably transfected CHO cells. Molecular Biotechnology. 57: 138-44. PMID 25307181 DOI: 10.1007/S12033-014-9809-2  0.357
2014 Mariati, Koh EY, Yeo JH, Ho SC, Yang Y. Toward stable gene expression in CHO cells. Bioengineered. 5: 340-5. PMID 25482237 DOI: 10.4161/Bioe.32111  0.368
2014 Gagnon P, Nian R, Tan L, Cheong J, Yeo V, Yang Y, Gan HT. Chromatin-mediated depression of fractionation performance on electronegative multimodal chromatography media, its prevention, and ramifications for purification of immunoglobulin G. Journal of Chromatography. A. 1374: 145-55. PMID 25481347 DOI: 10.1016/J.Chroma.2014.11.052  0.317
2014 Loh WP, Loo B, Zhou L, Zhang P, Lee DY, Yang Y, Lam KP. Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells. Biotechnology Journal. 9: 1140-51. PMID 24819042 DOI: 10.1002/Biot.201400050  0.39
2014 Mariati, Yeo JH, Koh EY, Ho SC, Yang Y. Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells. Biotechnology Progress. 30: 523-34. PMID 24789630 DOI: 10.1002/Btpr.1919  0.37
2014 Ho SC, Yang Y. Identifying and engineering promoters for high level and sustainable therapeutic recombinant protein production in cultured mammalian cells. Biotechnology Letters. 36: 1569-79. PMID 24737078 DOI: 10.1007/S10529-014-1523-4  0.433
2014 Gagnon P, Nian R, Lee J, Tan L, Latiff SMA, Lim CL, Chuah C, Bi X, Yang Y, Zhang W, Gan HT. Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance Journal of Chromatography A. 1340: 68-78. PMID 24661871 DOI: 10.1016/J.Chroma.2014.03.010  0.326
2013 Koh EY, Ho SC, Mariati, Song Z, Bi X, Bardor M, Yang Y. An internal ribosome entry site (IRES) mutant library for tuning expression level of multiple genes in mammalian cells. Plos One. 8: e82100. PMID 24349195 DOI: 10.1371/Journal.Pone.0082100  0.387
2013 Lai T, Yang Y, Ng SK. Advances in Mammalian cell line development technologies for recombinant protein production. Pharmaceuticals (Basel, Switzerland). 6: 579-603. PMID 24276168 DOI: 10.3390/Ph6050579  0.435
2013 Chung BK, Yusufi FN, Mariati, Yang Y, Lee DY. Enhanced expression of codon optimized interferon gamma in CHO cells. Journal of Biotechnology. 167: 326-33. PMID 23876479 DOI: 10.1016/J.Jbiotec.2013.07.011  0.357
2013 Ho SC, Bardor M, Li B, Lee JJ, Song Z, Tong YW, Goh LT, Yang Y. Comparison of internal ribosome entry site (IRES) and Furin-2A (F2A) for monoclonal antibody expression level and quality in CHO cells. Plos One. 8: e63247. PMID 23704898 DOI: 10.1371/Journal.Pone.0063247  0.371
2012 Lee J, Gan HT, Latiff SMA, Chuah C, Lee WY, Yang YS, Loo B, Ng SK, Gagnon P. Principles and applications of steric exclusion chromatography Journal of Chromatography A. 1270: 162-170. PMID 23182281 DOI: 10.1016/J.Chroma.2012.10.062  0.338
2012 Ho SC, Bardor M, Feng H, Mariati, Tong YW, Song Z, Yap MG, Yang Y. IRES-mediated Tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines. Journal of Biotechnology. 157: 130-9. PMID 22024589 DOI: 10.1016/J.Jbiotec.2011.09.023  0.431
2012 Mariati, Ho SC, Yap MG, Yang Y. Post-transcriptional regulatory elements for enhancing transient gene expression levels in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 801: 125-35. PMID 21987251 DOI: 10.1007/978-1-61779-352-3_9  0.379
2011 Feng HT, Sim LC, Wan C, Wong NS, Yang Y. Rapid characterization of protein productivity and production stability of CHO cells by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 25: 1407-12. PMID 21504006 DOI: 10.1002/Rcm.5011  0.427
2010 Zhang P, Tan DL, Heng D, Wang T, Mariati, Yang Y, Song Z. A functional analysis of N-glycosylation-related genes on sialylation of recombinant erythropoietin in six commonly used mammalian cell lines. Metabolic Engineering. 12: 526-36. PMID 20826224 DOI: 10.1016/J.Ymben.2010.08.004  0.426
2010 Yang Y, Mariati, Chusainow J, Yap MG. DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines. Journal of Biotechnology. 147: 180-5. PMID 20430058 DOI: 10.1016/J.Jbiotec.2010.04.004  0.418
2010 Mariati, Ng YK, Chao SH, Yap MG, Yang Y. Evaluating regulatory elements of human cytomegalovirus major immediate early gene for enhancing transgene expression levels in CHO K1 and HEK293 cells. Journal of Biotechnology. 147: 160-3. PMID 20416345 DOI: 10.1016/J.Jbiotec.2010.02.022  0.388
2010 Mariati, Ho SC, Yap MG, Yang Y. Evaluating post-transcriptional regulatory elements for enhancing transient gene expression levels in CHO K1 and HEK293 cells. Protein Expression and Purification. 69: 9-15. PMID 19899222 DOI: 10.1016/J.Pep.2009.08.010  0.377
2009 Yang Y, Ho SC, Yap MG. Mutated polyadenylation signals for controlling expression levels of multiple genes in mammalian cells. Biotechnology and Bioengineering. 102: 1152-60. PMID 18973284 DOI: 10.1002/Bit.22152  0.37
2004 Yang Y, Balcarcel RR. 96-well plate assay for sublethal metabolic activity. Assay and Drug Development Technologies. 2: 353-61. PMID 15357916 DOI: 10.1089/Adt.2004.2.353  0.691
2004 Yang Y, Balcarcel RR. Determination of carbon dioxide production rates for mammalian cells in 24-well plates. Biotechniques. 36: 286-90, 292, 294-5. PMID 14989093 DOI: 10.2144/04362Rr03  0.694
2003 Yang Y, Balcarcel RR. 24-well plate spectrophotometric assay for preliminary screening of metabolic activity. Assay and Drug Development Technologies. 1: 461-8. PMID 15090183 DOI: 10.1089/154065803322163777  0.701
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