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Gregory S. Yochum, Ph.D. - Publications

Affiliations: 
2002 University of Utah, Salt Lake City, UT 
Area:
Molecular Biology
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 King CM, Marx OM, Ding W, Koltun WA, Yochum GS. TCF7L1 Regulates Expression in Colorectal Cancer Cells. Genes. 14. PMID 36833408 DOI: 10.3390/genes14020481  0.354
2020 Rawat M, Nighot M, Al-Sadi R, Gupta Y, Viszwapriya D, Yochum G, Koltun W, Ma TY. IL1B Increases Intestinal Tight Junction Permeability by Upregulation of MIR200C-3p, Which Degrades Occludin mRNA. Gastroenterology. PMID 32569770 DOI: 10.1053/J.Gastro.2020.06.038  0.313
2020 Singh V, Gowda CP, Singh V, Ganapathy AS, Karamchandani DM, Eshelman MA, Yochum GS, Nighot P, Spiegelman VS. The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating Occludin expression. The Journal of Biological Chemistry. PMID 32385106 DOI: 10.1074/Jbc.Ac120.013646  0.347
2020 Eshelman M, Koltun W, Yochum GS. Sa1119 TRISTETRAPROLIN EXPRESSION IN THE INTESTINAL EPITHELIUM SUPPRESSES CHRONIC COLITIS AND COLITIS-ASSOCIATED CANCER Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)31393-7  0.3
2019 Eshelman MA, Jeganathan NA, Schieffer KM, Kline BP, Mendenhall M, Deiling S, Harris L, Koltun WA, Yochum GS. Elevated Colonic Mucin Expression Correlates with Extended Time to Surgery for Ulcerative Colitis Patients. Journal of Gastrointestinal and Liver Diseases : Jgld. 28: 405-413. PMID 31826065 DOI: 10.15403/Jgld-250  0.314
2019 Eshelman MA, Matthews SM, Schleicher EM, Fleeman RM, Kawasawa YI, Stumpo DJ, Blackshear PJ, Koltun WA, Ishmael FT, Yochum GS. Tristetraprolin targets Nos2 expression in the colonic epithelium. Scientific Reports. 9: 14413. PMID 31595002 DOI: 10.1038/S41598-019-50957-9  0.373
2019 Matthews SM, Eshelman MA, Berg AS, Koltun WA, Yochum GS. The Crohn's disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells. Plos One. 14: e0212850. PMID 30794691 DOI: 10.1371/Journal.Pone.0212850  0.371
2017 Schieffer KM, Choi CS, Emrich S, Harris L, Deiling S, Karamchandani DM, Salzberg A, Kawasawa YI, Yochum GS, Koltun WA. RNA-seq implicates deregulation of the immune system in the pathogenesis of diverticulitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00136.2017. PMID 28619727 DOI: 10.1152/Ajpgi.00136.2017  0.391
2017 Coble JL, Sheldon K, Yue F, Salameh T, Harris L, Deiling S, Ruggiero F, Eshelman M, Yochum GS, Koltun WA, Gerhard GS, Broach JR. Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing. Human Molecular Genetics. PMID 28595269 DOI: 10.1093/Hmg/Ddx204  0.358
2017 Eshelman MA, Shah M, Raup-Konsavage WM, Rennoll SA, Yochum GS. TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells. Biochemical and Biophysical Research Communications. PMID 28450117 DOI: 10.1016/J.Bbrc.2017.04.123  0.429
2016 Rennoll SA, Eshelman MA, Raup-Konsavage WM, Kawasawa YI, Yochum GS. The MYC 3' Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells. Cancers. 8. PMID 27223305 DOI: 10.3390/Cancers8050052  0.405
2016 Eshelman MA, Yochum GS. The Wnt/β-catenin pathway is activated by miR-1246 in liver cancer stem cells Translational Cancer Research. 5. DOI: 10.21037/Tcr.2016.12.57  0.341
2015 Song C, Pan X, Ge Z, Gowda C, Ding Y, Li H, Li Z, Yochum G, Muschen M, Li Q, Payne KJ, Dovat S. Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II (CK2) in leukemia. Leukemia. PMID 26639180 DOI: 10.1038/Leu.2015.331  0.42
2015 Rennoll S, Yochum G. Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer World Journal of Biological Chemistry. 6: 290-300. PMID 26629312 DOI: 10.4331/Wjbc.V6.I4.290  0.411
2015 Raup-Konsavage WM, Cooper TK, Yochum GS. A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice. Digestive Diseases and Sciences. PMID 26320084 DOI: 10.1007/S10620-015-3852-0  0.303
2015 Shah M, Rennoll SA, Raup-Konsavage WM, Yochum GS. A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells. Cell Cycle (Georgetown, Tex.). 14: 323-32. PMID 25659031 DOI: 10.4161/15384101.2014.980643  0.434
2014 Rennoll SA, Scott SA, Yochum GS. Targeted repression of AXIN2 and MYC gene expression using designer TALEs. Biochemical and Biophysical Research Communications. 446: 1120-5. PMID 24667606 DOI: 10.1016/J.Bbrc.2014.03.077  0.443
2014 Konsavage WM, Yochum GS. The myc 3' wnt-responsive element suppresses colonic tumorigenesis. Molecular and Cellular Biology. 34: 1659-69. PMID 24567369 DOI: 10.1128/Mcb.00969-13  0.406
2014 Rennoll SA, Konsavage WM, Yochum GS. Nuclear AXIN2 represses MYC gene expression. Biochemical and Biophysical Research Communications. 443: 217-22. PMID 24299953 DOI: 10.1016/J.Bbrc.2013.11.089  0.399
2013 Konsavage WM, Roper JN, Ishmael FT, Yochum GS. The Myc 3' Wnt responsive element regulates neutrophil recruitment after acute colonic injury in mice. Digestive Diseases and Sciences. 58: 2858-67. PMID 23640071 DOI: 10.1007/S10620-013-2686-X  0.347
2012 Konsavage WM, Jin G, Yochum GS. The Myc 3' Wnt-responsive element regulates homeostasis and regeneration in the mouse intestinal tract. Molecular and Cellular Biology. 32: 3891-902. PMID 22826434 DOI: 10.1128/Mcb.00548-12  0.434
2012 Konsavage WM, Kyler SL, Rennoll SA, Jin G, Yochum GS. Wnt/β-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells. The Journal of Biological Chemistry. 287: 11730-9. PMID 22337891 DOI: 10.1074/Jbc.M111.327767  0.389
2011 Yochum GS. Multiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loops. Plos One. 6: e18966. PMID 21533051 DOI: 10.1371/Journal.Pone.0018966  0.45
2010 Bottomly D, Kyler SL, McWeeney SK, Yochum GS. Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq. Nucleic Acids Research. 38: 5735-45. PMID 20460455 DOI: 10.1093/Nar/Gkq363  0.353
2010 Yochum GS, Sherrick CM, Macpartlin M, Goodman RH. A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers. Proceedings of the National Academy of Sciences of the United States of America. 107: 145-50. PMID 19966299 DOI: 10.1073/Pnas.0912294107  0.375
2009 McWeeney S, Yochum G, Pemberton LC, Loriaux M, Vartanian K, Willis SG, Wilmot B, Turpaz Y, Pillai R, partlin MM, Snead J, Druker BJ, O'Brien SG, Melo JV, Lange T, et al. A Gene Expression Signature of CD34+ Cells to Predict Major Cytogenetic Response in Chronic Phase Chronic Myeloid Leukemia Patients Treated with Imatinib: Potential Involvement of Beta-Catenin in Drug Resistance. Blood. 114: 508-508. DOI: 10.1182/Blood.V114.22.508.508  0.332
2008 Yochum GS, Cleland R, Goodman RH. A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. Molecular and Cellular Biology. 28: 7368-79. PMID 18852287 DOI: 10.1128/Mcb.00744-08  0.386
2007 Yochum GS, Rajaraman V, Cleland R, McWeeney S. Localization of TFIIB binding regions using serial analysis of chromatin occupancy Bmc Molecular Biology. 8. PMID 17997859 DOI: 10.1186/1471-2199-8-102  0.371
2007 Otto SJ, McCorkle SR, Hover J, Conaco C, Han JJ, Impey S, Yochum GS, Dunn JJ, Goodman RH, Mandel G. A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6729-39. PMID 17581960 DOI: 10.1523/Jneurosci.0091-07.2007  0.375
2007 Yochum GS, McWeeney S, Rajaraman V, Cleland R, Peters S, Goodman RH. Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 3324-9. PMID 17360646 DOI: 10.1073/Pnas.0611576104  0.393
2007 Yochum GS, Cleland R, McWeeney S, Goodman RH. An antisense transcript induced by Wnt/beta-catenin signaling decreases E2F4. The Journal of Biological Chemistry. 282: 871-8. PMID 17121828 DOI: 10.1074/Jbc.M609391200  0.409
2004 Impey S, McCorkle SR, Cha-Molstad H, Dwyer JM, Yochum GS, Boss JM, McWeeney S, Dunn JJ, Mandel G, Goodman RH. Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell. 119: 1041-54. PMID 15620361 DOI: 10.1016/J.Cell.2004.10.032  0.398
2004 Cha-Molstad H, Keller DM, Yochum GS, Impey S, Goodman RH. Cell-type-specific binding of the transcription factor CREB to the cAMP-response element. Proceedings of the National Academy of Sciences of the United States of America. 101: 13572-7. PMID 15342915 DOI: 10.1073/Pnas.0405587101  0.415
2002 Yochum GS, Ayer DE. Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split. Molecular and Cellular Biology. 22: 7868-76. PMID 12391155 DOI: 10.1128/Mcb.22.22.7868-7876.2002  0.657
2001 Yochum GS, Ayer DE. Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex. Molecular and Cellular Biology. 21: 4110-8. PMID 11390640 DOI: 10.1128/Mcb.21.13.4110-4118.2001  0.644
2000 Brubaker K, Cowley SM, Huang K, Loo L, Yochum GS, Ayer DE, Eisenman RN, Radhakrishnan I. Solution structure of the interacting domains of the Mad-Sin3 complex: implications for recruitment of a chromatin-modifying complex. Cell. 103: 655-65. PMID 11106735 DOI: 10.1016/S0092-8674(00)00168-9  0.666
1998 Laherty CD, Billin AN, Lavinsky RM, Yochum GS, Bush AC, Sun JM, Mullen TM, Davie JR, Rose DW, Glass CK, Rosenfeld MG, Ayer DE, Eisenman RN. SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Molecular Cell. 2: 33-42. PMID 9702189 DOI: 10.1016/S1097-2765(00)80111-2  0.667
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