| Year |
Citation |
Score |
| 2023 |
Lalwani RC, Volmar CH, Wahlestedt C, Webster KA, Shehadeh LA. Contextualizing the Role of Osteopontin in the Inflammatory Responses of Alzheimer's Disease. Biomedicines. 11. PMID 38137453 DOI: 10.3390/biomedicines11123232 |
0.623 |
|
| 2023 |
Dennison J, Mendez A, Szeto A, Lohse I, Wahlestedt C, Volmar CH. Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse. Biomolecules. 13. PMID 37759724 DOI: 10.3390/biom13091324 |
0.642 |
|
| 2023 |
McCartan R, Khorkova O, Volmar CH, Wahlestedt C. Nucleic acid-based therapeutics for the treatment of central nervous system disorders. Frontiers in Genetics. 14: 1250276. PMID 37662844 DOI: 10.3389/fgene.2023.1250276 |
0.617 |
|
| 2023 |
Khorkova O, Stahl J, Joji A, Volmar CH, Zeier Z, Wahlestedt C. Long non-coding RNA-targeting therapeutics: discovery and development update. Expert Opinion On Drug Discovery. 1-19. PMID 37466388 DOI: 10.1080/17460441.2023.2236552 |
0.649 |
|
| 2023 |
Stokes T, Cen HH, Kapranov P, Gallagher IJ, Pitsillides AA, Volmar CH, Kraus WE, Johnson JD, Phillips SM, Wahlestedt C, Timmons JA. Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq. Advanced Genetics (Hoboken, N.J.). 4: 2200024. PMID 37288167 DOI: 10.1002/ggn2.202200024 |
0.642 |
|
| 2023 |
Khorkova O, Stahl J, Joji A, Volmar CH, Wahlestedt C. Amplifying gene expression with RNA-targeted therapeutics. Nature Reviews. Drug Discovery. PMID 37253858 DOI: 10.1038/s41573-023-00704-7 |
0.664 |
|
| 2023 |
Ricciardi NR, Modarresi F, Lohse I, Andrade NS, Newman IR, Brown JM, Borja C, Marples B, Wahlestedt CR, Volmar CH. Investigating the Synergistic Potential of Low-Dose HDAC3 Inhibition and Radiotherapy in Alzheimer's Disease Models. Molecular Neurobiology. PMID 37171575 DOI: 10.1007/s12035-023-03373-0 |
0.659 |
|
| 2022 |
Khorkova O, Stahl J, Joji A, Volmar CH, Zeier Z, Wahlestedt C. Natural antisense transcripts as drug targets. Frontiers in Molecular Biosciences. 9: 978375. PMID 36250017 DOI: 10.3389/fmolb.2022.978375 |
0.65 |
|
| 2022 |
Dennison JL, Al-Ali H, Volmar CH, Brothers S, Watts J, Wahlestedt C, Lohse I. Functional Drug Screening of Small Molecule Inhibitors of Epigenetic Modifiers in Refractory AML Patients. Cancers. 14. PMID 36077629 DOI: 10.3390/cancers14174094 |
0.65 |
|
| 2022 |
Kemper C, Benham D, Brothers S, Wahlestedt C, Volmar CH, Bennett D, Hayward M. Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL ). Aaps Open. 8: 11. PMID 35789594 DOI: 10.1186/s41120-022-00058-1 |
0.608 |
|
| 2022 |
Dennison JL, Volmar CH, Modarresi F, Ke D, Wang J, Gravel E, Hammond-Vignini S, Li Z, Timmons JA, Lohse I, Hayward MA, Brothers SP, Wahlestedt C. Erratum to: JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model. Journal of Alzheimer's Disease : Jad. PMID 35723129 DOI: 10.3233/JAD-229006 |
0.61 |
|
| 2022 |
Timmons JA, Anighoro A, Brogan RJ, Stahl J, Wahlestedt C, Farquhar DG, Taylor-King J, Volmar CH, Kraus WE, Phillips SM. A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease. Elife. 11. PMID 35037854 DOI: 10.7554/eLife.68832 |
0.651 |
|
| 2022 |
Dennison JL, Volmar CH, Ke D, Wang J, Gravel E, Hammond-Vignini S, Li Z, Timmons JA, Lohse I, Hayward MA, Brothers SP, Wahlestedt C. JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model. Journal of Alzheimer's Disease : Jad. PMID 35034905 DOI: 10.3233/JAD-215370 |
0.63 |
|
| 2021 |
Modarresi F, Pedram Fatemi R, Razavipour SF, Ricciardi N, Makhmutova M, Khoury N, Magistri M, Volmar CH, Wahlestedt C, Faghihi MA. A novel knockout mouse model of the noncoding antisense () gene displays increased endogenous Bdnf protein and improved memory function following exercise. Heliyon. 7: e07570. PMID 34377851 DOI: 10.1016/j.heliyon.2021.e07570 |
0.611 |
|
| 2021 |
Dennison JL, Ricciardi NR, Lohse I, Volmar CH, Wahlestedt C. Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research. Journal of Alzheimer's Disease : Jad. PMID 33459720 DOI: 10.3233/JAD-201014 |
0.604 |
|
| 2020 |
Kuznetsoff JN, Owens DA, Lopez A, Rodriguez DA, Chee NT, Kurtenbach S, Bilbao D, Roberts ER, Volmar CH, Wahlestedt C, Brothers SP, Harbour JW. Dual screen for efficacy and toxicity identifies HDAC inhibitor with distinctive activity spectrum for BAP1-mutant uveal melanoma. Molecular Cancer Research : McR. PMID 33077485 DOI: 10.1158/1541-7786.MCR-20-0434 |
0.641 |
|
| 2020 |
Alvarez-Trotta A, Wang Z, Shersher E, Li B, Long J, Lohse I, Wahlestedt C, El-Rifai W, Robbins DJ, Capobianco AJ. The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling. Oncotarget. 11: 3174-3187. PMID 32913560 DOI: 10.18632/Oncotarget.27699 |
0.327 |
|
| 2020 |
Spriano F, Gaudio E, Cascione L, Tarantelli C, Melle F, Motta G, Priebe V, Rinaldi A, Golino G, Mensah AA, Aresu L, Zucca E, Pileri S, Witcher M, Brown B, ... Wahlestedt C, et al. Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734. Blood Advances. 4: 4124-4135. PMID 32882003 DOI: 10.1182/Bloodadvances.2020001879 |
0.321 |
|
| 2020 |
Wahlestedt C, Khorkova O. Direct Administration and Gene Modulation Using Antisense Oligonucleotides Within the CNS. Cellular and Molecular Neurobiology. PMID 32656646 DOI: 10.1007/S10571-020-00919-X |
0.307 |
|
| 2020 |
Owens DA, Kuznetsov JN, Lopez A, Kurtenbach S, Bilbao D, Roberts ER, Volmar C, Wahlestedt CR, Harbour JW. Abstract 4025: New candidate therapy for BAP1-mutant cancer identified using novel screen Cancer Research. 80: 4025-4025. DOI: 10.1158/1538-7445.Am2020-4025 |
0.638 |
|
| 2019 |
Lohse I, Azzam DJ, Al-Ali H, Volmar CH, Brothers SP, Ince TA, Wahlestedt C. Ovarian Cancer Treatment Stratification Using Drug Sensitivity Testing. Anticancer Research. 39: 4023-4030. PMID 31366484 DOI: 10.21873/Anticanres.13558 |
0.64 |
|
| 2019 |
Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, ... ... Wahlestedt C, et al. Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Nature Communications. 10: 3126. PMID 31311938 DOI: 10.1038/S41467-019-11004-3 |
0.311 |
|
| 2019 |
Timmons JA, Volmar CH, Crossland H, Phillips BE, Sood S, Janczura KJ, Törmäkangas T, Kujala UM, Kraus WE, Atherton PJ, Wahlestedt C. Longevity-related molecular pathways are subject to midlife "switch" in humans. Aging Cell. e12970. PMID 31168962 DOI: 10.1111/Acel.12970 |
0.67 |
|
| 2019 |
Mustafi S, Camarena V, Qureshi R, Yoon H, Volmar CH, Huff TC, Sant DW, Zheng L, Brothers SP, Wahlestedt C, Slingerland J, Wang G. Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer. Ebiomedicine. PMID 30975544 DOI: 10.1016/J.Ebiom.2019.04.006 |
0.629 |
|
| 2019 |
Bagheri A, Habibzadeh P, Razavipour SF, Volmar CH, Chee NT, Brothers SP, Wahlestedt C, Mowla SJ, Faghihi MA. HDAC Inhibitors Induce Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons. International Journal of Molecular Sciences. 20. PMID 30841499 DOI: 10.3390/ijms20051109 |
0.636 |
|
| 2019 |
Khomtchouk BB, Koehler WC, Van Booven DJ, Wahlestedt C. Optimized functional annotation of ChIP-seq data F1000research. 8: 612. DOI: 10.12688/F1000Research.18966.1 |
0.309 |
|
| 2019 |
Copsel S, Lightbourn CO, Barreras H, Lohse I, Wolf D, Bader CS, Manov J, Kale B, Shah D, Brothers S, Perez VL, Komanduri KV, Wahlestedt C, Levy RB. Identification of a BET Bromodomain Inhibitor That Enables Treg Function: A Combinatorial Strategy to Inhibit GVHD Biology of Blood and Marrow Transplantation. 25: S25-S26. DOI: 10.1016/J.Bbmt.2018.12.095 |
0.301 |
|
| 2018 |
Janczura KJ, Volmar CH, Wahlestedt C. Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue. Journal of Visualized Experiments : Jove. PMID 30582583 DOI: 10.3791/58648 |
0.617 |
|
| 2018 |
Stathias V, Jermakowicz AM, Maloof ME, Forlin M, Walters W, Suter RK, Durante MA, Williams SL, Harbour JW, Volmar CH, Lyons NJ, Wahlestedt C, Graham RM, Ivan ME, Komotar RJ, et al. Drug and disease signature integration identifies synergistic combinations in glioblastoma. Nature Communications. 9: 5315. PMID 30552330 DOI: 10.1038/S41467-018-07659-Z |
0.685 |
|
| 2018 |
Sartor GC, Malvezzi AM, Kumar A, Andrade NS, Wiedner HJ, Vilca SJ, Janczura KJ, Bagheri A, Al-Ali H, Powell SK, Brown PT, Volmar CH, Foster TC, Zeier Z, Wahlestedt C. Enhancement of BDNF expression and memory by HDAC inhibition requires BET bromodomain reader proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30504275 DOI: 10.1523/Jneurosci.1604-18.2018 |
0.352 |
|
| 2018 |
Janczura KJ, Volmar CH, Sartor GC, Rao SJ, Ricciardi NR, Lambert G, Brothers SP, Wahlestedt C. Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model. Proceedings of the National Academy of Sciences of the United States of America. PMID 30397132 DOI: 10.1073/Pnas.1805436115 |
0.667 |
|
| 2018 |
Lohse I, Al-Ali H, Volmar CH, D Alvarez Trotta A, Brothers SP, Capobianco AJ, Wahlestedt C. Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma. Plos One. 13: e0203173. PMID 30212533 DOI: 10.1371/Journal.Pone.0203173 |
0.615 |
|
| 2018 |
Timmons JA, Atherton PJ, Larsson O, Sood S, Blokhin IO, Brogan RJ, Volmar CH, Josse AR, Slentz C, Wahlestedt C, Phillips SM, Phillips BE, Gallagher IJ, Kraus WE. A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease. Nucleic Acids Research. PMID 29986096 DOI: 10.1093/Nar/Gky570 |
0.641 |
|
| 2018 |
Brothers S, Volmar C, Bodamer O, Hayward M, Wahlestedt C. Novel small molecule therapy development for MPS I Molecular Genetics and Metabolism. 123: S26. DOI: 10.1016/J.Ymgme.2017.12.043 |
0.622 |
|
| 2018 |
Volmar C, Salah-Uddin H, Janczura KJ, Halley P, Lambert G, Wodrich A, Manoah S, Patel NH, Sartor GC, Mehta N, Miles NT, Desse S, Dorcius D, Cameron MD, Brothers SP, ... Wahlestedt C, et al. 112. Multipronged HDAC Strategy for Alzheimer’s Disease Biological Psychiatry. 83: S46. DOI: 10.1016/J.Biopsych.2018.02.130 |
0.638 |
|
| 2017 |
Mustafi S, Camarena V, Volmar CH, Huff TC, Sant DW, Brothers SP, Liu ZJ, Wahlestedt C, Wang G. Vitamin C sensitizes melanoma to BET inhibitors. Cancer Research. PMID 29180474 DOI: 10.1158/0008-5472.Can-17-2040 |
0.648 |
|
| 2017 |
Swords RT, Azzam D, Al-Ali H, Lohse I, Volmar CH, Watts JM, Perez A, Rodriguez A, Vargas F, Elias R, Vega F, Zelent A, Brothers SP, Abbasi T, Trent J, ... ... Wahlestedt C, et al. Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study. Leukemia Research. 64: 34-41. PMID 29175379 DOI: 10.1016/J.Leukres.2017.11.008 |
0.617 |
|
| 2017 |
Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, ... ... Wahlestedt C, et al. Gain-of-function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies. Blood. PMID 29113963 DOI: 10.1182/Blood-2017-06-789669 |
0.339 |
|
| 2017 |
Volmar CH, Salah-Uddin H, Janczura KJ, Halley P, Lambert G, Wodrich A, Manoah S, Patel NH, Sartor GC, Mehta N, Miles NTH, Desse S, Dorcius D, Cameron MD, Brothers SP, ... Wahlestedt C, et al. M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory. Proceedings of the National Academy of Sciences of the United States of America. 114: E9135-E9144. PMID 29073110 DOI: 10.1073/Pnas.1707544114 |
0.648 |
|
| 2017 |
Sartor GC, Powell SK, Velmeshev D, Lin DY, Magistri M, Wiedner HJ, Malvezzi AM, Andrade NS, Faghihi MA, Wahlestedt C. Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens. Molecular and Cellular Neurosciences. PMID 29055697 DOI: 10.1016/J.Mcn.2017.10.003 |
0.344 |
|
| 2017 |
Esanov R, Cabrera GT, Andrade NS, Gendron TF, Brown RH, Benatar M, Wahlestedt C, Mueller C, Zeier Z. A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD. Molecular Neurodegeneration. 12: 46. PMID 28606110 DOI: 10.1186/S13024-017-0185-9 |
0.319 |
|
| 2016 |
Witt AE, Lee CW, Lee TI, Azzam DJ, Wang B, Caslini C, Petrocca F, Grosso J, Jones M, Cohick EB, Gropper AB, Wahlestedt C, Richardson AL, Shiekhattar R, Young RA, et al. Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer. Oncogene. PMID 27694895 DOI: 10.1038/Onc.2016.337 |
0.338 |
|
| 2016 |
Magistri M, Velmeshev D, Makhmutova M, Patel P, Sartor GC, Volmar CH, Wahlestedt C, Faghihi MA. The BET-bromodomain inhibitor JQ1 reduces inflammation and tau phosphorylation at Ser396 in the brain of the 3xTg model of Alzheimer's disease. Current Alzheimer Research. PMID 27117003 DOI: 10.2174/1567205013666160427101832 |
0.649 |
|
| 2016 |
Laurent GS, Vyatkin Y, Antonets D, Ri M, Qi Y, Saik O, Shtokalo D, de Hoon MJ, Kawaji H, Itoh M, Lassmann T, Arner E, Forrest AR, Nicolas E, ... ... Wahlestedt C, et al. Functional annotation of the vlinc class of non-coding RNAs using systems biology approach. Nucleic Acids Research. PMID 27001520 DOI: 10.1093/Nar/Gkw162 |
0.329 |
|
| 2016 |
Volmar CH, Wahlestedt C, Brothers SP. Orphan diseases: state of the drug discovery art. Wiener Medizinische Wochenschrift (1946). PMID 26819216 DOI: 10.1007/s10354-015-0423-0 |
0.628 |
|
| 2015 |
Peschansky VJ, Pastori C, Zeier Z, Motti D, Wentzel K, Velmeshev D, Magistri M, Bixby JL, Lemmon VP, Silva JP, Wahlestedt C. Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells. Frontiers in Genetics. 6: 263. PMID 26322075 DOI: 10.3389/Fgene.2015.00263 |
0.355 |
|
| 2015 |
Pedram Fatemi R, Salah-Uddin S, Modarresi F, Khoury N, Wahlestedt C, Faghihi MA. Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen. Journal of Biomolecular Screening. 20: 1132-41. PMID 26173710 DOI: 10.1177/1087057115594187 |
0.367 |
|
| 2015 |
Pastori C, Kapranov P, Penas C, Peschansky V, Volmar CH, Sarkaria JN, Bregy A, Komotar R, St Laurent G, Ayad NG, Wahlestedt C. The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation. Proceedings of the National Academy of Sciences of the United States of America. 112: 8326-31. PMID 26111795 DOI: 10.1073/Pnas.1424220112 |
0.693 |
|
| 2015 |
Zeier Z, Esanov R, Belle KC, Volmar CH, Johnstone AL, Halley P, DeRosa BA, Khoury N, van Blitterswijk M, Rademakers R, Albert J, Brothers SP, Wuu J, Dykxhoorn DM, Benatar M, ... Wahlestedt C, et al. Bromodomain inhibitors regulate the C9ORF72 locus in ALS. Experimental Neurology. 271: 241-50. PMID 26099177 DOI: 10.1016/J.Expneurol.2015.06.017 |
0.678 |
|
| 2015 |
Yamanaka Y, Faghihi MA, Magistri M, Alvarez-Garcia O, Lotz M, Wahlestedt C. Antisense RNA controls LRP1 Sense transcript expression through interaction with a chromatin-associated protein, HMGB2. Cell Reports. 11: 967-76. PMID 25937287 DOI: 10.1016/J.Celrep.2015.04.011 |
0.379 |
|
| 2015 |
Swords RT, Brothers S, Ayad N, Perez A, Watts JM, Vargas F, Elias R, Rodriguez A, Johnstone S, Albert J, Collard J, Zelent A, Wahlestedt C. The BET Bromodomain Inhibitors EP11313 and EP11336 Have Potent Anti-Leukemic Activity in Acute Myeloid Leukemia (AML) and Augment the Effects of All-Trans-Retinoic Acid (AtRA) in Vitro Blood. 126: 2552-2552. DOI: 10.1182/Blood.V126.23.2552.2552 |
0.338 |
|
| 2015 |
Azzam D, Volmar C, Hassan A, Perez A, Watts JM, Vargas F, Elias R, Vega F, Zelent A, Cogle CR, Wahlestedt C, Swords RT. A Patient-Specific Ex Vivo Screening Platform for Personalized Acute Myeloid Leukemia (AML) Therapy Blood. 126: 1352-1352. DOI: 10.1182/Blood.V126.23.1352.1352 |
0.664 |
|
| 2015 |
Pastori C, Kapranov P, Penas C, Laurent GS, Ayad N, Wahlestedt C. Abstract 4764: The Bromodomain inhibitors regulate long noncoding RNAs controlling glioblastoma progression Cancer Research. 75: 4764-4764. DOI: 10.1158/1538-7445.Am2015-4764 |
0.393 |
|
| 2015 |
Volmar C, Wahlestedt C. Histone deacetylases (HDACs) and brain function Neuroepigenetics. 1: 20-27. DOI: 10.1016/j.nepig.2014.10.002 |
0.604 |
|
| 2015 |
Zeier Z, Esanov R, Belle KC, Volmar CH, Johnstone AL, Halley P, DeRosa BA, Khoury N, van Blitterswijk M, Rademakers R, Albert J, Brothers SP, Wuu J, Dykxhoorn DM, Benatar M, ... Wahlestedt C, et al. Bromodomain inhibitors regulate the C9ORF72 locus in ALS Experimental Neurology. 271: 241-250. DOI: 10.1016/j.expneurol.2015.06.017 |
0.597 |
|
| 2014 |
Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. The Journal of Biological Chemistry. 289: 35494-502. PMID 25355313 DOI: 10.1074/Jbc.M114.595348 |
0.674 |
|
| 2014 |
Plotkin A, Volmar CH, Wahlestedt C, Ayad N, El-Ashry D. Transcriptional repression of ER through hMAPK dependent histone deacetylation by class I HDACs. Breast Cancer Research and Treatment. 147: 249-63. PMID 25129342 DOI: 10.1007/S10549-014-3093-5 |
0.616 |
|
| 2014 |
Kang MJ, Abdelmohsen K, Hutchison ER, Mitchell SJ, Grammatikakis I, Guo R, Noh JH, Martindale JL, Yang X, Lee EK, Faghihi MA, Wahlestedt C, Troncoso JC, Pletnikova O, Perrone-Bizzozero N, et al. HuD regulates coding and noncoding RNA to induce APP→Aβ processing. Cell Reports. 7: 1401-9. PMID 24857657 DOI: 10.1016/J.Celrep.2014.04.050 |
0.343 |
|
| 2014 |
Peschansky VJ, Wahlestedt C. Non-coding RNAs as direct and indirect modulators of epigenetic regulation. Epigenetics : Official Journal of the Dna Methylation Society. 9: 3-12. PMID 24739571 DOI: 10.4161/Epi.27473 |
0.368 |
|
| 2014 |
Pastori C, Daniel M, Penas C, Volmar CH, Johnstone AL, Brothers SP, Graham RM, Allen B, Sarkaria JN, Komotar RJ, Wahlestedt C, Ayad NG. BET bromodomain proteins are required for glioblastoma cell proliferation. Epigenetics : Official Journal of the Dna Methylation Society. 9: 611-20. PMID 24496381 DOI: 10.4161/Epi.27906 |
0.67 |
|
| 2014 |
Pastori C, Peschansky VJ, Barbouth D, Mehta A, Silva JP, Wahlestedt C. Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome. Human Genetics. 133: 59-67. PMID 24005575 DOI: 10.1007/S00439-013-1356-6 |
0.333 |
|
| 2014 |
Pastori C, Penas C, Kapranov P, Laurent GS, Zhang M, Ayad N, Wahlestedt C. Abstract LB-114: The long noncoding RNA HOTAIR promotes glioblastoma cell proliferation Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-114 |
0.399 |
|
| 2014 |
Johnstone S, Johhnsone A, Penas C, Stathias V, Brothers S, Ayad N, Wahlestedt C, Albert J. EG-04 * DEVELOPMENT OF HIGHLY POTENT, SELECTIVE BET BROMODOMAIN INHIBITORS THAT ARE CNS PENETRANT AND EFFECTIVE IN RODENT MODELS OF BRAIN CANCER Neuro-Oncology. 16: v75-v75. DOI: 10.1093/Neuonc/Nou254.4 |
0.367 |
|
| 2014 |
Pastori C, Kapranov P, Penas C, Laurent GS, Ayad N, Wahlestedt C. EG-10 * LONG NON-CODING RNAs IN GLIOBLASTOMA Neuro-Oncology. 16: v77-v77. DOI: 10.1093/Neuonc/Nou254.10 |
0.395 |
|
| 2014 |
Wahlestedt C. Erratum: Targeting long non-coding RNA to therapeutically upregulate gene expression. Nature Reviews Drug Discovery. 13: 79-79. DOI: 10.1038/Nrd4203 |
0.315 |
|
| 2013 |
Khorkova O, Hsiao J, Wahlestedt C. Oligonucleotides for upregulating gene expression. Pharmaceutical Patent Analyst. 2: 215-29. PMID 24237027 DOI: 10.4155/Ppa.13.4 |
0.342 |
|
| 2013 |
Clarke J, Penas C, Pastori C, Komotar RJ, Bregy A, Shah AH, Wahlestedt C, Ayad NG. Epigenetic pathways and glioblastoma treatment. Epigenetics : Official Journal of the Dna Methylation Society. 8: 785-95. PMID 23807265 DOI: 10.4161/Epi.25440 |
0.307 |
|
| 2012 |
Peschansky VJ, Liang Z, Wahlestedt C. RNAi joins the "Singles Club". Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2010-1. PMID 23131851 DOI: 10.1038/Mt.2012.218 |
0.359 |
|
| 2012 |
Sartor GC, St Laurent G, Wahlestedt C. The Emerging Role of Non-Coding RNAs in Drug Addiction. Frontiers in Genetics. 3: 106. PMID 22737160 DOI: 10.3389/Fgene.2012.00106 |
0.354 |
|
| 2012 |
Magistri M, Faghihi MA, St Laurent G, Wahlestedt C. Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts. Trends in Genetics : Tig. 28: 389-96. PMID 22541732 DOI: 10.1016/J.Tig.2012.03.013 |
0.367 |
|
| 2012 |
Modarresi F, Faghihi MA, Lopez-Toledano MA, Fatemi RP, Magistri M, Brothers SP, van der Brug MP, Wahlestedt C. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nature Biotechnology. 30: 453-9. PMID 22446693 DOI: 10.1038/Nbt.2158 |
0.363 |
|
| 2011 |
Modarresi F, Faghihi MA, Patel NS, Sahagan BG, Wahlestedt C, Lopez-Toledano MA. Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. International Journal of Alzheimer's Disease. 2011: 929042. PMID 21785702 DOI: 10.4061/2011/929042 |
0.356 |
|
| 2011 |
Clark MB, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, Ponting CP, Stadler PF, Morris KV, Morillon A, Rozowsky JS, Gerstein MB, Wahlestedt C, Hayashizaki Y, Carninci P, et al. The reality of pervasive transcription. Plos Biology. 9: e1000625; discussion. PMID 21765801 DOI: 10.1371/Journal.Pbio.1000625 |
0.312 |
|
| 2010 |
Faghihi MA, Kocerha J, Modarresi F, Engström PG, Chalk AM, Brothers SP, Koesema E, St Laurent G, Wahlestedt C. RNAi screen indicates widespread biological function for human natural antisense transcripts. Plos One. 5. PMID 20957177 DOI: 10.1371/Journal.Pone.0013177 |
0.345 |
|
| 2010 |
Silva JP, Wahlestedt C. Role of Sirtuin 1 in metabolic regulation. Drug Discovery Today. 15: 781-91. PMID 20621197 DOI: 10.1016/J.Drudis.2010.07.001 |
0.302 |
|
| 2010 |
Faghihi MA, Zhang M, Huang J, Modarresi F, Van der Brug MP, Nalls MA, Cookson MR, St-Laurent G, Wahlestedt C. Evidence for natural antisense transcript-mediated inhibition of microRNA function. Genome Biology. 11: R56. PMID 20507594 DOI: 10.1186/Gb-2010-11-5-R56 |
0.321 |
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| 2010 |
Lopez-Toledano MA, Ali Faghihi M, Patel NS, Wahlestedt C. Adult neurogenesis: a potential tool for early diagnosis in Alzheimer's disease? Journal of Alzheimer's Disease : Jad. 20: 395-408. PMID 20164555 DOI: 10.3233/Jad-2010-1388 |
0.302 |
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| 2010 |
Timmons JA, Knudsen S, Rankinen T, Koch LG, Sarzynski M, Jensen T, Keller P, Scheele C, Vollaard NB, Nielsen S, Akerström T, MacDougald OA, Jansson E, Greenhaff PL, Tarnopolsky MA, ... ... Wahlestedt C, et al. Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. Journal of Applied Physiology (Bethesda, Md. : 1985). 108: 1487-96. PMID 20133430 DOI: 10.1152/Japplphysiol.01295.2009 |
0.303 |
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| 2009 |
St Laurent G, Faghihi MA, Wahlestedt C. Non-coding RNA transcripts: sensors of neuronal stress, modulators of synaptic plasticity, and agents of change in the onset of Alzheimer's disease. Neuroscience Letters. 466: 81-8. PMID 19699259 DOI: 10.1016/J.Neulet.2009.08.032 |
0.351 |
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| 2009 |
Faghihi MA, Wahlestedt C. Regulatory roles of natural antisense transcripts. Nature Reviews. Molecular Cell Biology. 10: 637-43. PMID 19638999 DOI: 10.1038/Nrm2738 |
0.323 |
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| 2009 |
Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, ... ... Wahlestedt C, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics. 41: 553-62. PMID 19377474 DOI: 10.1038/Ng.375 |
0.301 |
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| 2008 |
Shan G, Li Y, Zhang J, Li W, Szulwach KE, Duan R, Faghihi MA, Khalil AM, Lu L, Paroo Z, Chan AW, Shi Z, Liu Q, Wahlestedt C, He C, et al. A small molecule enhances RNA interference and promotes microRNA processing. Nature Biotechnology. 26: 933-40. PMID 18641635 DOI: 10.1038/Nbt.1481 |
0.336 |
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| 2008 |
Faghihi MA, Modarresi F, Khalil AM, Wood DE, Sahagan BG, Morgan TE, Finch CE, St Laurent G, Kenny PJ, Wahlestedt C. Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nature Medicine. 14: 723-30. PMID 18587408 DOI: 10.1038/Nm1784 |
0.353 |
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| 2008 |
Dahlgren C, Zhang HY, Du Q, Grahn M, Norstedt G, Wahlestedt C, Liang Z. Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Research. 36: e53. PMID 18420656 DOI: 10.1093/Nar/Gkn190 |
0.316 |
|
| 2008 |
Hong J, Wei N, Chalk A, Wang J, Song Y, Yi F, Qiao RP, Sonnhammer EL, Wahlestedt C, Liang Z, Du Q. Focusing on RISC assembly in mammalian cells. Biochemical and Biophysical Research Communications. 368: 703-8. PMID 18252196 DOI: 10.1016/J.Bbrc.2008.01.116 |
0.313 |
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| 2008 |
Khalil AM, Faghihi MA, Modarresi F, Brothers SP, Wahlestedt C. A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. Plos One. 3: e1486. PMID 18213394 DOI: 10.1371/Journal.Pone.0001486 |
0.348 |
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| 2006 |
Larsson O, Perlman DM, Fan D, Reilly CS, Peterson M, Dahlgren C, Liang Z, Li S, Polunovsky VA, Wahlestedt C, Bitterman PB. Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Research. 34: 4375-86. PMID 16936314 DOI: 10.1093/Nar/Gkl558 |
0.319 |
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| 2006 |
Zhang HY, Du Q, Wahlestedt C, Liang Z. RNA Interference with chemically modified siRNA. Current Topics in Medicinal Chemistry. 6: 893-900. PMID 16787282 DOI: 10.2174/156802606777303676 |
0.347 |
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| 2006 |
Wahlestedt C. Natural antisense and noncoding RNA transcripts as potential drug targets. Drug Discovery Today. 11: 503-8. PMID 16713901 DOI: 10.1016/J.Drudis.2006.04.013 |
0.354 |
|
| 2006 |
Faghihi MA, Wahlestedt C. RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals. Genome Biology. 7: R38. PMID 16684369 DOI: 10.1186/Gb-2006-7-5-R38 |
0.346 |
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| 2006 |
Engström PG, Suzuki H, Ninomiya N, Akalin A, Sessa L, Lavorgna G, Brozzi A, Luzi L, Tan SL, Yang L, Kunarso G, Ng EL, Batalov S, Wahlestedt C, Kai C, et al. Complex Loci in human and mouse genomes. Plos Genetics. 2: e47. PMID 16683030 DOI: 10.1371/Journal.Pgen.0020047 |
0.302 |
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| 2006 |
Frith MC, Wilming LG, Forrest A, Kawaji H, Tan SL, Wahlestedt C, Bajic VB, Kai C, Kawai J, Carninci P, Hayashizaki Y, Bailey TL, Huminiecki L. Pseudo-messenger RNA: phantoms of the transcriptome. Plos Genetics. 2: e23. PMID 16683022 DOI: 10.1371/Journal.Pgen.0020023 |
0.344 |
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| 2006 |
Dahlgren C, Wahlestedt C, Thonberg H. No induction of anti-viral responses in human cell lines HeLa and MCF-7 when transfecting with siRNA or siLNA. Biochemical and Biophysical Research Communications. 341: 1211-7. PMID 16476582 DOI: 10.1016/J.Bbrc.2006.01.085 |
0.304 |
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| 2006 |
Volmar C, Janczura KJ, Lambert G, Salah-Uddin H, Halley P, Sartor GC, Brothers SP, Wahlestedt C. P4-220: MULTIFACTORIAL EPIGENETIC STRATEGY FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1527-P1527. DOI: 10.1016/J.Jalz.2018.07.041 |
0.64 |
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| 2005 |
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, ... ... Wahlestedt C, et al. Antisense transcription in the mammalian transcriptome. Science (New York, N.Y.). 309: 1564-6. PMID 16141073 DOI: 10.1126/Science.1112009 |
0.344 |
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| 2005 |
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, ... ... Wahlestedt C, et al. The transcriptional landscape of the mammalian genome. Science (New York, N.Y.). 309: 1559-63. PMID 16141072 DOI: 10.1126/Science.1112014 |
0.31 |
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| 2005 |
Timmons JA, Larsson O, Jansson E, Fischer H, Gustafsson T, Greenhaff PL, Ridden J, Rachman J, Peyrard-Janvid M, Wahlestedt C, Sundberg CJ. Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 750-60. PMID 15857889 DOI: 10.1096/Fj.04-1980Com |
0.302 |
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| 2005 |
Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z. A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Research. 33: 1671-7. PMID 15781493 DOI: 10.1093/Nar/Gki647 |
0.316 |
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| 2005 |
Chen M, Zhang L, Zhang HY, Xiong X, Wang B, Du Q, Lu B, Wahlestedt C, Liang Z. A universal plasmid library encoding all permutations of small interfering RNA. Proceedings of the National Academy of Sciences of the United States of America. 102: 2356-61. PMID 15695593 DOI: 10.1073/Pnas.0401549101 |
0.332 |
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| 2005 |
Elmén J, Thonberg H, Ljungberg K, Frieden M, Westergaard M, Xu Y, Wahren B, Liang Z, Ørum H, Koch T, Wahlestedt C. Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Research. 33: 439-47. PMID 15653644 DOI: 10.1093/Nar/Gki193 |
0.343 |
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| 2005 |
Pang KC, Stephen S, Engström PG, Tajul-Arifin K, Chen W, Wahlestedt C, Lenhard B, Hayashizaki Y, Mattick JS. RNAdb--a comprehensive mammalian noncoding RNA database. Nucleic Acids Research. 33: D125-30. PMID 15608161 DOI: 10.1093/Nar/Gki089 |
0.352 |
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| 2004 |
Thonberg H, Schéele CC, Dahlgren C, Wahlestedt C. Characterization of RNA interference in rat PC12 cells: requirement of GERp95. Biochemical and Biophysical Research Communications. 318: 927-34. PMID 15147961 DOI: 10.1016/J.Bbrc.2004.04.119 |
0.318 |
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| 2004 |
Xu Y, Linde A, Larsson O, Thormeyer D, Elmen J, Wahlestedt C, Liang Z. Functional comparison of single- and double-stranded siRNAs in mammalian cells. Biochemical and Biophysical Research Communications. 316: 680-7. PMID 15033453 DOI: 10.1016/J.Bbrc.2004.02.100 |
0.303 |
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| 2004 |
Larsson O, Scheele C, Liang Z, Moll J, Karlsson C, Wahlestedt C. Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model. Cancer Research. 64: 482-9. PMID 14744760 DOI: 10.1158/0008-5472.Can-03-1872 |
0.301 |
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| 2002 |
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, ... ... Wahlestedt C, et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 420: 563-73. PMID 12466851 DOI: 10.1038/Nature01266 |
0.331 |
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| 2000 |
Hoja MR, Wahlestedt C, Höög C. A visual intracellular classification strategy for uncharacterized human proteins. Experimental Cell Research. 259: 239-46. PMID 10942595 DOI: 10.1006/Excr.2000.4948 |
0.306 |
|
| 1996 |
Weng G, Feinstein D, Reis D, Wahlestedt C. Neuropeptide Y receptor gene regulation in mouse adrenocortical Y-1 cells. Regulatory Peptides. 63: 53-6. PMID 8795089 DOI: 10.1016/0167-0115(96)00030-4 |
0.327 |
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