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Patricia Spear - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
herpes simplex virus
Website:
http://bugs.mimnet.northwestern.edu/labs/Faculty/spearp.html

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Yoon M, Kopp SJ, Taylor JM, Storti CS, Spear PG, Muller WJ. Functional interaction between herpes simplex virus type 2 gD and HVEM transiently dampens local chemokine production after murine mucosal infection. Plos One. 6: e16122. PMID 21283640 DOI: 10.1371/journal.pone.0016122  0.309
2009 Aubert M, Yoon M, Sloan DD, Spear PG, Jerome KR. The virological synapse facilitates herpes simplex virus entry into T cells. Journal of Virology. 83: 6171-83. PMID 19339346 DOI: 10.1128/JVI.02163-08  0.319
2008 Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H. PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B. Cell. 132: 935-44. PMID 18358807 DOI: 10.1016/J.Cell.2008.01.043  0.305
2004 Manoj S, Jogger CR, Myscofski D, Yoon M, Spear PG. Mutations in herpes simplex virus glycoprotein D that prevent cell entry via nectins and alter cell tropism. Proceedings of the National Academy of Sciences of the United States of America. 101: 12414-21. PMID 15273289 DOI: 10.1073/pnas.0404211101  0.318
2003 Spear PG, Longnecker R. Herpesvirus entry: an update. Journal of Virology. 77: 10179-85. PMID 12970403 DOI: 10.1128/Jvi.77.19.10179-10185.2003  0.342
2002 Yoon M, Spear PG. Disruption of adherens junctions liberates nectin-1 to serve as receptor for herpes simplex virus and pseudorabies virus entry. Journal of Virology. 76: 7203-8. PMID 12072519  0.333
2001 Shukla D, Spear PG. Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry. The Journal of Clinical Investigation. 108: 503-10. PMID 11518721 DOI: 10.1172/Jci13799  0.349
2001 Pertel PE, Fridberg A, Parish ML, Spear PG. Cell fusion induced by herpes simplex virus glycoproteins gB, gD, and gH-gL requires a gD receptor but not necessarily heparan sulfate. Virology. 279: 313-24. PMID 11145912 DOI: 10.1006/Viro.2000.0713  0.331
2000 Spear PG, Eisenberg RJ, Cohen GH. Three classes of cell surface receptors for alphaherpesvirus entry. Virology. 275: 1-8. PMID 11017782 DOI: 10.1006/Viro.2000.0529  0.4
2000 Leventhal JR, Martinez WM, Roszkowski JJ, Fryer JP, Kaufman DB, Abecassis MI, Stuart FP, Spear PG. PORCINE CELLS ARE SUSCEPTIBLE TO INFECTION BY HUMAN HERPES SIMPLEX VIRUS. Transplantation. 69: S418. DOI: 10.1097/00007890-200004271-01171  0.336
1999 Shukla D, Rowe CL, Dong Y, Racaniello VR, Spear PG. The murine homolog (Mph) of human herpesvirus entry protein B (HveB) mediates entry of pseudorabies virus but not herpes simplex virus types 1 and 2. Journal of Virology. 73: 4493-7. PMID 10196354 DOI: 10.1128/Jvi.73.5.4493-4497.1999  0.327
1998 Warner MS, Geraghty RJ, Martinez WM, Montgomery RI, Whitbeck JC, Xu R, Eisenberg RJ, Cohen GH, Spear PG. A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies virus. Virology. 246: 179-89. PMID 9657005 DOI: 10.1006/Viro.1998.9218  0.335
1998 Terry-Allison T, Montgomery RI, Whitbeck JC, Xu R, Cohen GH, Eisenberg RJ, Spear PG. HveA (herpesvirus entry mediator A), a coreceptor for herpes simplex virus entry, also participates in virus-induced cell fusion. Journal of Virology. 72: 5802-10. PMID 9621040 DOI: 10.1128/Jvi.72.7.5802-5810.1998  0.355
1998 Geraghty RJ, Krummenacher C, Cohen GH, Eisenberg RJ, Spear PG. Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor. Science (New York, N.Y.). 280: 1618-20. PMID 9616127 DOI: 10.1126/Science.280.5369.1618  0.327
1996 Montgomery RI, Warner MS, Lum BJ, Spear PG. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family. Cell. 87: 427-36. PMID 8898196 DOI: 10.1016/S0092-8674(00)81363-X  0.342
1996 Novotny MJ, Parish ML, Spear PG. Variability of herpes simplex virus 1 gL and anti-gL antibodies that inhibit cell fusion but not viral infectivity. Virology. 221: 1-13. PMID 8661409 DOI: 10.1006/VIRO.1996.0347  0.349
1995 Dean HJ, Warner MS, Terhune SS, Johnson RM, Spear PG. Viral determinants of the variable sensitivity of herpes simplex virus strains to gD-mediated interference Journal of Virology. 69: 5171-5176. PMID 7609090 DOI: 10.1128/Jvi.69.8.5171-5176.1995  0.326
1994 Shieh MT, Spear PG. Herpesvirus-induced cell fusion that is dependent on cell surface heparan sulfate or soluble heparin. Journal of Virology. 68: 1224-8. PMID 8289356 DOI: 10.1128/JVI.68.2.1224-1228.1994  0.343
1994 Herold BC, Visalli RJ, Susmarski N, Brandt CR, Spear PG. Glycoprotein C-independent binding of herpes simplex virus to cells requires cell surface heparan sulphate and glycoprotein B. The Journal of General Virology. 1211-22. PMID 8207388 DOI: 10.1099/0022-1317-75-6-1211  0.329
1992 Spear PG, Shieh MT, Herold BC, WuDunn D, Koshy TI. Heparan sulfate glycosaminoglycans as primary cell surface receptors for herpes simplex virus. Advances in Experimental Medicine and Biology. 313: 341-53. PMID 1332443 DOI: 10.1007/978-1-4899-2444-5_33  0.357
1992 Shieh MT, WuDunn D, Montgomery RI, Esko JD, Spear PG. Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans Journal of Cell Biology. 116: 1273-1281. PMID 1310996 DOI: 10.1083/Jcb.116.5.1273  0.367
1991 Herold BC, WuDunn D, Soltys N, Spear PG. Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity. Journal of Virology. 65: 1090-8. PMID 1847438 DOI: 10.1128/JVI.65.3.1090-1098.1991  0.323
1991 Wittels M, Spear PG. Penetration of cells by herpes simplex virus does not require a low pH-dependent endocytic pathway. Virus Research. 18: 271-90. PMID 1645908 DOI: 10.1016/0168-1702(91)90024-P  0.313
1989 Fuller AO, Santos RE, Spear PG. Neutralizing antibodies specific for glycoprotein H of herpes simplex virus permit viral attachment to cells but prevent penetration. Journal of Virology. 63: 3435-43. PMID 2545914 DOI: 10.1128/JVI.63.8.3435-3443.1989  0.367
1989 Johnson RM, Spear PG. Herpes simplex virus glycoprotein D mediates interference with herpes simplex virus infection Journal of Virology. 63: 819-827. PMID 2536105 DOI: 10.1128/JVI.63.2.819-827.1989  0.349
1989 WuDunn D, Spear PG. Initial interaction of herpes simplex virus with cells is binding to heparan sulfate. Journal of Virology. 63: 52-8. PMID 2535752 DOI: 10.1128/JVI.63.1.52-58.1989  0.317
1988 Martin TE, Barghusen SC, Leser GP, Spear PG. Redistribution of nuclear ribonucleoprotein antigens during herpes simplex virus infection. The Journal of Cell Biology. 105: 2069-82. PMID 2824525 DOI: 10.1083/JCB.105.5.2069  0.314
1987 Fuller AO, Spear PG. Anti-glycoprotein D antibodies that permit adsorption but block infection by herpes simplex virus 1 prevent virion-cell fusion at the cell surface. Proceedings of the National Academy of Sciences of the United States of America. 84: 5454-8. PMID 3037552 DOI: 10.1073/PNAS.84.15.5454  0.348
1987 McNearney TA, Odell C, Holers VM, Spear PG, Atkinson JP. Herpes simplex virus glycoproteins gC-1 and gC-2 bind to the third component of complement and provide protection against complement-mediated neutralization of viral infectivity Journal of Experimental Medicine. 166: 1525-1535. PMID 2824652  0.301
1986 Claesson-Welsh L, Spear PG. Oligomerization of herpes simplex virus glycoprotein B. Journal of Virology. 60: 803-6. PMID 3022014 DOI: 10.1128/JVI.60.2.803-806.1986  0.324
1984 Johnson DC, Wittels M, Spear PG. Binding to cells of virosomes containing herpes simplex virus type 1 glycoproteins and evidence for fusion. Journal of Virology. 52: 238-47. PMID 6090699 DOI: 10.1128/JVI.52.1.238-247.1984  0.327
1983 Para MF, Zezulak KM, Conley AJ, Weinberger M, Snitzer K, Spear PG. Use of monoclonal antibodies against two 75,000-molecular-weight glycoproteins specified by herpes simplex virus type 2 in glycoprotein identification and gene mapping. Journal of Virology. 45: 1223-7. PMID 6300459 DOI: 10.1128/JVI.45.3.1223-1227.1983  0.307
1983 Johnson DC, Spear PG. Monensin inhibits the processing of herpes simplex virus glycoproteins, their transport to the cell surface, and the egress of virions from infected cells. Journal of Virology. 43: 1102-12. PMID 6292453 DOI: 10.1128/JVI.43.3.1102-1112.1982  0.379
1982 Para MF, Goldstein L, Spear PG. Similarities and differences in the Fc-binding glycoprotein (gE) of herpes simplex virus types 1 and 2 and tentative mapping of the viral gene for this glycoprotein. Journal of Virology. 41: 137-44. PMID 6283108 DOI: 10.1128/JVI.41.1.137-144.1982  0.339
1982 Para MF, Baucke RB, Spear PG. Glycoprotein gE of herpes simplex virus type 1: effects of anti-gE on virion infectivity and on virus-induced fc-binding receptors. Journal of Virology. 41: 129-36. PMID 6283107 DOI: 10.1128/JVI.41.1.129-136.1982  0.334
1981 Wei CM, Gibson M, Spear PG, Scolnick EM. Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1. Journal of Virology. 39: 935-44. PMID 6270359 DOI: 10.1128/JVI.39.3.935-944.1981  0.325
1981 Lee GT, Spear PG. Viral and cellular factors that influence cell fusion induced by herpes simplex virus. Virology. 107: 402-14. PMID 6256940 DOI: 10.1016/0042-6822(80)90307-4  0.316
1980 Baucke RB, Spear PG. Membrane proteins specified by herpes simplex viruses. V. Identification of an Fc-binding glycoprotein. Journal of Virology. 32: 779-89. PMID 229267 DOI: 10.1128/JVI.32.3.779-789.1979  0.345
1979 Sarmiento M, Haffey M, Spear PG. Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7(B2) in virion infectivity. Journal of Virology. 29: 1149-58. PMID 221669 DOI: 10.1128/JVI.29.3.1149-1158.1979  0.346
1977 Manservigi R, Spear PG, Buchan A. Cell fusion induced by herpes simplex virus is promoted and suppressed by different viral glycoproteins. Proceedings of the National Academy of Sciences. 74: 3913-3917. DOI: 10.1073/PNAS.74.9.3913  0.33
1976 Leiden JM, Buttyan R, Spear PG. Herpes simplex virus gene expression in transformed cells. I. Regulation of the viral thymidine kinase gene in transformed L cells by products of superinfecting virus. Journal of Virology. 20: 413-24. PMID 185425 DOI: 10.1128/JVI.20.2.413-424.1976  0.331
1976 Spear PG. Membrane proteins specified by herpes simplex viruses. I. Identification of four glycoprotein precursors and their products in type 1-infected cells. Journal of Virology. 17: 991-1008. PMID 176453 DOI: 10.1128/JVI.17.3.991-1008.1976  0.346
1974 Spear PG, Edelman GM. Maturation of the humoral immune response in mice. The Journal of Experimental Medicine. 139: 249-63. PMID 4589987 DOI: 10.1084/Jem.139.2.249  0.424
1973 Millette CF, Spear PG, Gall WE, Edelman GM. Chemical dissection of mammalian spermatozoa. The Journal of Cell Biology. 58: 662-75. PMID 4747921 DOI: 10.1083/jcb.58.3.662  0.379
1973 Spear PG, Wang AL, Rutishauser U, Edelman GM. Characterization of splenic lymphoid cells in fetal and newborn mice. The Journal of Experimental Medicine. 138: 557-73. PMID 4580464 DOI: 10.1084/Jem.138.3.557  0.61
1972 Heine JW, Spear PG, Roizman B. Proteins specified by herpes simplex virus. VI. Viral proteins in the plasma membrane. Journal of Virology. 9: 431-9. PMID 4111436 DOI: 10.1128/Jvi.9.3.431-439.1972  0.499
1972 Spear PG, Roizman B. Proteins specified by herpes simplex virus. V. Purification and structural proteins of the herpesvirion. Journal of Virology. 9: 143-59. PMID 4110104 DOI: 10.1128/Jvi.9.1.143-159.1972  0.492
1971 Roizman B, Spear PG. Herpesvirus antigens on cell membranes detected by centrifugation of membrane-antibody complexes. Science (New York, N.Y.). 171: 298-300. PMID 4321391 DOI: 10.1126/Science.171.3968.298  0.475
1971 Lee LF, Kieff ED, Bachenheimer SL, Roizman B, Spear PG, Burmester BR, Nazerian K. Size and composition of Marek's disease virus deoxyribonucleic acid. Journal of Virology. 7: 289-94. PMID 4101222 DOI: 10.1128/Jvi.7.3.289-294.1971  0.57
1970 Wagner EK, Roizman B, Savage T, Spear PG, Mizell M, Durr FE, Sypowicz D. Characterization of the DNA of herpesviruses associated with Lucké adenocarcinoma of the frog and Burkitt lymphoma of man. Virology. 42: 257-61. PMID 5460136 DOI: 10.1016/0042-6822(70)90265-5  0.384
1970 Roizman B, Keller JM, Spear PG, Terni M, Nahmias A, Dowdle W. Variability, structural glycoproteins, and classification of herpes simplex viruses. Nature. 227: 1253-4. PMID 4318128 DOI: 10.1038/2271253A0  0.471
1970 Spear PG, Roizman B. Proteins specified by herpes simplex virus, IV. Site of glycosylation and accumulation of viral membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 66: 730-7. PMID 4316680 DOI: 10.1073/Pnas.66.3.730  0.461
1970 Spear PG, Kellejmroian B. Proteins spcified by herpes simplex virus. II. Viral glycoprotins associated with cellular membranes. Journal of Virology. 5: 123-31. PMID 4315403 DOI: 10.1128/JVI.5.2.123-131.1970  0.341
1970 Keller JM, Spear PG, Roizman B. Proteins specified by herpes simplex virus. 3. Viruses differing in their effects on the social behavior of infected cells specify different membrane glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. 65: 865-71. PMID 4314902 DOI: 10.1073/Pnas.65.4.865  0.514
1969 Roizman B, Spear PG. Macromolecular biosynthesis in animal cells infected with cytolytic viruses. Current Topics in Developmental Biology. 4: 79-108. PMID 4331968 DOI: 10.1016/S0070-2153(08)60481-0  0.464
1969 Lee LF, Roizman B, Spear PG, Kieff ED, Burmester BR, Nazerian K. Marek's disease herpes virus: a cytomegalovirus. Proceedings of the National Academy of Sciences of the United States of America. 64: 952-6. PMID 4313336 DOI: 10.1073/Pnas.64.3.952  0.593
1969 Spring SB, Roizman B, Spear PG. Selective failure of protein synthesis in herpesvirus-infected cells deprived of arginine. Virology. 38: 710-2. PMID 4308568 DOI: 10.1016/0042-6822(69)90193-7  0.428
1968 Spear PG, Roizman B. An improved procedure for H-3 and C-14 counting in acrylamide gels with a nonaqueous scintillation system. Analytical Biochemistry. 26: 197-200. PMID 5758032 DOI: 10.1016/0003-2697(68)90048-1  0.312
1968 Roizman B, Spear PG. Preparation of herpes simplex virus of high titer. Journal of Virology. 2: 83-4. PMID 4316015 DOI: 10.1128/Jvi.2.1.83-84.1968  0.467
1968 Spear PG, Roizman B. The proteins specified by herpes simplex virus. I. Time of synthesis, transfer into nuclei, and properties of proteins made in productively infected cells. Virology. 36: 545-55. PMID 4302003 DOI: 10.1016/0042-6822(68)90186-4  0.472
1967 Spear PG, Roizman B. Buoyant density of herpes simplex virus in solutions of caesium chloride. Nature. 214: 713-4. PMID 4292804 DOI: 10.1038/214713A0  0.45
1966 Morris VL, Spear PG, Roizman B. Some biophysical properties of frog viruses and their DNA. Proceedings of the National Academy of Sciences of the United States of America. 56: 1155-7. PMID 4961525 DOI: 10.1073/Pnas.56.4.1155  0.428
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