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Bi-Sen Ding, Ph.D. - Publications

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Pharmacology
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen X, Wang H, Wu C, Li X, Huang X, Ren Y, Pu Q, Cao Z, Tang X, Ding BS. Endothelial HS-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis. Redox Biology. 70: 103038. PMID 38266576 DOI: 10.1016/j.redox.2024.103038  0.317
2023 Yan M, Li H, Xu S, Wu J, Li J, Xiao C, Mo C, Ding BS. Targeting Endothelial Necroptosis Disrupts Profibrotic Endothelial-Hepatic Stellate Cells Crosstalk to Alleviate Liver Fibrosis in Nonalcoholic Steatohepatitis. International Journal of Molecular Sciences. 24. PMID 37511074 DOI: 10.3390/ijms241411313  0.335
2023 Deng Y, Huang X, Hu Y, Zhong W, Zhang H, Mo C, Wang H, Ding BS, Wang C. Deficiency of endothelial FGFR1 signaling via upregulation of ROCK2 activity aggravated ALI/ARDS. Frontiers in Immunology. 14: 1041533. PMID 36969192 DOI: 10.3389/fimmu.2023.1041533  0.432
2022 Chen Y, Ding BS. Comprehensive Review of the Vascular Niche in Regulating Organ Regeneration and Fibrosis. Stem Cells Translational Medicine. PMID 36169406 DOI: 10.1093/stcltm/szac070  0.375
2021 Hisata S, Racanelli AC, Kermani P, Schreiner R, Houghton S, Palikuqi B, Kunar B, Zhou A, McConn K, Capili A, Redmond D, Nolan DJ, Ginsberg M, Ding BS, Martinez FJ, et al. Reversal of emphysema by restoration of pulmonary endothelial cells. The Journal of Experimental Medicine. 218. PMID 34287647 DOI: 10.1084/jem.20200938  0.396
2021 Ren Y, Zhang Y, Wang L, He F, Yan M, Liu X, Ou Y, Wu Q, Bi T, Wang S, Liu J, Ding BS, Wang L, Qing J. Selective Targeting of Vascular Endothelial YAP Activity Blocks EndMT and Ameliorates Unilateral Ureteral Obstruction-Induced Kidney Fibrosis. Acs Pharmacology & Translational Science. 4: 1066-1074. PMID 34151201 DOI: 10.1021/acsptsci.1c00010  0.384
2020 Chen Y, Pu Q, Ma Y, Zhang H, Ye T, Zhao C, Huang X, Ren Y, Qiao L, Liu HM, Esmon CT, Ding BS, Cao Z. Aging Reprograms the Hematopoietic-Vascular Niche to Impede Regeneration and Promote Fibrosis. Cell Metabolism. PMID 33357457 DOI: 10.1016/j.cmet.2020.11.019  0.374
2020 Lu T, Lin X, Pan YH, Yang N, Ye S, Zhang Q, Wang C, Zhu R, Zhang T, Wisniewski TM, Cao Z, Ding BS, Dang S, Zhang W. ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation. Iscience. 23: 101472. PMID 32882513 DOI: 10.1016/J.Isci.2020.101472  0.314
2020 Ding BS, Yang D, Swendeman SL, Christoffersen C, Nielsen LB, Friedman SL, Powell CA, Hla T, Cao Z. Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair. Developmental Cell. PMID 32544390 DOI: 10.1016/J.Devcel.2020.05.024  0.386
2017 Shido K, Chavez D, Cao Z, Ko J, Rafii S, Ding BS. Platelets prime hematopoietic and vascular niche to drive angiocrine-mediated liver regeneration. Signal Transduction and Targeted Therapy. 2. PMID 29201496 DOI: 10.1038/Sigtrans.2016.44  0.361
2017 Guo P, Poulos MG, Palikuqi B, Badwe CR, Lis R, Kunar B, Ding BS, Rabbany SY, Shido K, Butler JM, Rafii S. Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression. The Journal of Clinical Investigation. PMID 29058691 DOI: 10.1172/Jci92309  0.449
2017 Kedem A, Aelion-Brauer A, Guo P, Wen D, Ding BS, Lis R, Cheng D, Sandler VM, Rafii S, Rosenwaks Z. Activated ovarian endothelial cells promote early follicular development and survival. Journal of Ovarian Research. 10: 64. PMID 28927438 DOI: 10.1186/S13048-017-0354-Z  0.347
2017 Cao Z, Ye T, Sun Y, Ji G, Shido K, Chen Y, Luo L, Na F, Li X, Huang Z, Ko JL, Mittal V, Qiao L, Chen C, Martinez FJ, ... ... Ding BS, et al. Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis. Science Translational Medicine. 9. PMID 28855398 DOI: 10.1126/Scitranslmed.Aai8710  0.322
2017 Lee KS, Santagostino SF, Li D, Ramjit A, Serrano K, Ginsberg MD, Ding BS, Rafii S, Madoff DC. Catheter-directed Intraportal Delivery of Endothelial Cell Therapy for Liver Regeneration: A Feasibility Study in a Large-Animal Model of Cirrhosis. Radiology. 162617. PMID 28498793 DOI: 10.1148/Radiol.2017162617  0.401
2017 Hao H, Hu S, Chen H, Bu D, Zhu L, Xu C, Chu F, Huo X, Tang Y, Sun X, Ding B, Liu D, Hu S, Wang M. Loss of Endothelial CXCR7 Impairs Vascular Homeostasis, and Cardiac Remodeling After Myocardial Infarction: Implications for Cardiovascular Drug Discovery. Circulation. PMID 28154007 DOI: 10.1161/Circulationaha.116.023027  0.368
2016 Ding BS, Liu CH, Sun Y, Chen Y, Swendeman SL, Jung B, Chavez D, Cao Z, Christoffersen C, Nielsen LB, Schwab SR, Rafii S, Hla T. HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver. Jci Insight. 1: e87058. PMID 28018969 DOI: 10.1172/Jci.Insight.87058  0.349
2016 Cao Z, Scandura JM, Inghirami GG, Shido K, Ding BS, Rafii S. Molecular Checkpoint Decisions Made by Subverted Vascular Niche Transform Indolent Tumor Cells into Chemoresistant Cancer Stem Cells. Cancer Cell. PMID 27989801 DOI: 10.1016/J.Ccell.2016.11.010  0.309
2016 Atapattu L, Saha N, Chheang C, Eissman MF, Xu K, Vail ME, Hii L, Llerena C, Liu Z, Horvay K, Abud HE, Kusebauch U, Moritz RL, Ding BS, Cao Z, et al. An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth. The Journal of Experimental Medicine. PMID 27503072 DOI: 10.1084/Jem.20151095  0.386
2016 Rafii S, Ginsberg M, Scandura J, Butler JM, Ding BS. Transplantation of Endothelial Cells to Mitigate Acute and Chronic Radiation Injury to Vital Organs. Radiation Research. PMID 27459700 DOI: 10.1667/Rr14461.1  0.374
2016 Rafii S, Butler JM, Ding BS. Angiocrine functions of organ-specific endothelial cells. Nature. 529: 316-25. PMID 26791722 DOI: 10.1038/Nature17040  0.409
2016 Cao Z, Lis R, Ginsberg M, Chavez D, Shido K, Rabbany SY, Fong GH, Sakmar TP, Rafii S, Ding BS. Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis. Nature Medicine. PMID 26779814 DOI: 10.1038/Nm.4035  0.414
2015 Ding BS, Gomi K, Rafii S, Crystal RG, Walters MS. Endothelial MMP14 is required for endothelial dependent growth support of human airway basal cells. Journal of Cell Science. PMID 26116571 DOI: 10.1242/Dev.129791  0.432
2015 Greineder CF, Brenza JB, Carnemolla R, Zaitsev S, Hood ED, Pan DC, Ding BS, Esmon CT, Chacko AM, Muzykantov VR. Dual targeting of therapeutics to endothelial cells: collaborative enhancement of delivery and effect. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25953848 DOI: 10.1096/Fj.15-271213  0.765
2015 Rafii S, Cao Z, Lis R, Siempos II, Chavez D, Shido K, Rabbany SY, Ding BS. Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration. Nature Cell Biology. 17: 123-36. PMID 25621952 DOI: 10.1038/Ncb3096  0.407
2015 Kao DI, Lacko LA, Ding BS, Huang C, Phung K, Gu G, Rafii S, Stuhlmann H, Chen S. Endothelial cells control pancreatic cell fate at defined stages through EGFL7 signaling. Stem Cell Reports. 4: 181-9. PMID 25601205 DOI: 10.1016/J.Stemcr.2014.12.008  0.418
2014 Cao Z, Ding BS, Guo P, Lee SB, Butler JM, Casey SC, Simons M, Tam W, Felsher DW, Shido K, Rafii A, Scandura JM, Rafii S. Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance. Cancer Cell. 25: 350-65. PMID 24651014 DOI: 10.1016/J.Ccr.2014.02.005  0.398
2014 Ding BS, Cao Z, Lis R, Nolan DJ, Guo P, Simons M, Penfold ME, Shido K, Rabbany SY, Rafii S. Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis. Nature. 505: 97-102. PMID 24256728 DOI: 10.1038/Nature12681  0.412
2014 Israely E, Ginsberg M, Nolan D, Ding BS, James D, Elemento O, Rafii S, Rabbany SY. Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells. Stem Cells (Dayton, Ohio). 32: 177-90. PMID 23963623 DOI: 10.1002/Stem.1521  0.491
2013 Greineder CF, Chacko AM, Zaytsev S, Zern BJ, Carnemolla R, Hood ED, Han J, Ding BS, Esmon CT, Muzykantov VR. Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor. Plos One. 8: e80110. PMID 24244621 DOI: 10.1371/Journal.Pone.0080110  0.751
2013 Carnemolla R, Greineder CF, Chacko AM, Patel KR, Ding BS, Zaitsev S, Esmon CT, Muzykantov VR. Platelet endothelial cell adhesion molecule targeted oxidant-resistant mutant thrombomodulin fusion protein with enhanced potency in vitro and in vivo. The Journal of Pharmacology and Experimental Therapeutics. 347: 339-45. PMID 23965383 DOI: 10.1124/Jpet.113.205104  0.728
2013 Nolan DJ, Ginsberg M, Israely E, Palikuqi B, Poulos MG, James D, Ding BS, Schachterle W, Liu Y, Rosenwaks Z, Butler JM, Xiang J, Rafii A, Shido K, Rabbany SY, et al. Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration. Developmental Cell. 26: 204-19. PMID 23871589 DOI: 10.1016/J.Devcel.2013.06.017  0.389
2013 Rafii S, Kloss CC, Butler JM, Ginsberg M, Gars E, Lis R, Zhan Q, Josipovic P, Ding BS, Xiang J, Elemento O, Zaninovic N, Rosenwaks Z, Sadelain M, Rafii JA, et al. Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition. Blood. 121: 770-80. PMID 23169780 DOI: 10.1182/Blood-2012-07-444208  0.42
2012 Ginsberg M, James D, Ding BS, Nolan D, Geng F, Butler JM, Schachterle W, Pulijaal VR, Mathew S, Chasen ST, Xiang J, Rosenwaks Z, Shido K, Elemento O, Rabbany SY, et al. Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression. Cell. 151: 559-75. PMID 23084400 DOI: 10.1016/J.Cell.2012.09.032  0.468
2012 Jung B, Obinata H, Galvani S, Mendelson K, Ding BS, Skoura A, Kinzel B, Brinkmann V, Rafii S, Evans T, Hla T. Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development. Developmental Cell. 23: 600-10. PMID 22975328 DOI: 10.1016/J.Devcel.2012.07.015  0.413
2012 Zaitsev S, Kowalska MA, Neyman M, Carnemolla R, Tliba S, Ding BS, Stonestrom A, Spitzer D, Atkinson JP, Poncz M, Cines DB, Esmon CT, Muzykantov VR. Targeting recombinant thrombomodulin fusion protein to red blood cells provides multifaceted thromboprophylaxis. Blood. 119: 4779-85. PMID 22493296 DOI: 10.1182/Blood-2011-12-398149  0.63
2012 Curradi G, Walters MS, Ding BS, Rafii S, Hackett NR, Crystal RG. Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells. Cellular and Molecular Life Sciences : Cmls. 69: 2217-31. PMID 22382924 DOI: 10.1007/S00018-012-0922-8  0.327
2011 Dang S, Hong T, Ding BS, Zhang W. A humanized single-chain variable fragment antibody against beta3 integrin in escherichia coli Hybridoma. 30: 543-548. PMID 22149280 DOI: 10.1089/Hyb.2011.0056  0.331
2011 Kimura Y, Ding B, Imai N, Nolan DJ, Butler JM, Rafii S. C-kit-mediated functional positioning of stem cells to their niches is essential for maintenance and regeneration of adult hematopoiesis Plos One. 6. PMID 22046410 DOI: 10.1371/Journal.Pone.0026918  0.315
2011 Ding BS, Nolan DJ, Guo P, Babazadeh AO, Cao Z, Rosenwaks Z, Crystal RG, Simons M, Sato TN, Worgall S, Shido K, Rabbany SY, Rafii S. Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell. 147: 539-53. PMID 22036563 DOI: 10.1016/J.Cell.2011.10.003  0.418
2011 Hormigo A, Ding BS, Rafii S. A target for antiangiogenic therapy: vascular endothelium derived from glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 108: 4271-2. PMID 21383166 DOI: 10.1073/Pnas.1019656108  0.412
2010 Ding BS, Nolan DJ, Butler JM, James D, Babazadeh AO, Rosenwaks Z, Mittal V, Kobayashi H, Shido K, Lyden D, Sato TN, Rabbany SY, Rafii S. Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. Nature. 468: 310-5. PMID 21068842 DOI: 10.1038/Nature09493  0.33
2010 Kobayashi H, Butler JM, O'Donnell R, Kobayashi M, Ding BS, Bonner B, Chiu VK, Nolan DJ, Shido K, Benjamin L, Rafii S. Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nature Cell Biology. 12: 1046-56. PMID 20972423 DOI: 10.1038/Ncb2108  0.447
2010 Zaitsev S, Spitzer D, Murciano JC, Ding BS, Tliba S, Kowalska MA, Marcos-Contreras OA, Kuo A, Stepanova V, Atkinson JP, Poncz M, Cines DB, Muzykantov VR. Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation. Blood. 115: 5241-8. PMID 20410503 DOI: 10.1182/Blood-2010-01-261610  0.592
2010 Zaitsev S, Zaitzev S, Spitzer D, Murciano JC, Ding BS, Tliba S, Kowalska MA, Bdeir K, Kuo A, Stepanova V, Atkinson JP, Poncz M, Cines DB, Muzykantov VR. Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis. The Journal of Pharmacology and Experimental Therapeutics. 332: 1022-31. PMID 19952305 DOI: 10.1124/Jpet.109.159194  0.621
2009 Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR. Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation. American Journal of Respiratory and Critical Care Medicine. 180: 247-56. PMID 19342415 DOI: 10.1164/Rccm.200809-1433Oc  0.591
2009 Simone E, Ding BS, Muzykantov V. Targeted delivery of therapeutics to endothelium. Cell and Tissue Research. 335: 283-300. PMID 18815813 DOI: 10.1007/S00441-008-0676-7  0.725
2008 Danielyan K, Ganguly K, Ding BS, Atochin D, Zaitsev S, Murciano JC, Huang PL, Kasner SE, Cines DB, Muzykantov VR. Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator. Circulation. 118: 1442-9. PMID 18794394 DOI: 10.1161/Circulationaha.107.750257  0.524
2008 Ding BS, Hong N, Murciano JC, Ganguly K, Gottstein C, Christofidou-Solomidou M, Albelda SM, Fisher AB, Cines DB, Muzykantov VR. Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature. Blood. 111: 1999-2006. PMID 18045968 DOI: 10.1182/Blood-2007-07-103002  0.605
2007 Danielyan K, Ding BS, Gottstein C, Cines DB, Muzykantov VR. Delivery of anti-platelet-endothelial cell adhesion molecule single-chain variable fragment-urokinase fusion protein to the cerebral vasculature lyses arterial clots and attenuates postischemic brain edema. The Journal of Pharmacology and Experimental Therapeutics. 321: 947-52. PMID 17389242 DOI: 10.1124/Jpet.107.120535  0.606
2006 Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. Advanced drug delivery systems that target the vascular endothelium. Molecular Interventions. 6: 98-112. PMID 16565472 DOI: 10.1124/Mi.6.2.7  0.657
2005 Ding BS, Gottstein C, Grunow A, Kuo A, Ganguly K, Albelda SM, Cines DB, Muzykantov VR. Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature. Blood. 106: 4191-8. PMID 16144802 DOI: 10.1182/Blood-2005-05-2002  0.658
2005 Zhou YJ, Wang SQ, Zhang J, Zhang W, Bi F, Guo ZG, Ding BS, Kumar P, Liu JN, Tan XY. A novel method to isolate and map endothelial membrane proteins from pulmonary vasculature. American Journal of Physiology. Cell Physiology. 288: C950-6. PMID 15590900 DOI: 10.1152/Ajpcell.00262.2004  0.451
2003 Ding BS, Zhou YJ, Chen XY, Zhang J, Zhang PX, Sun ZY, Tan XY, Liu JN. Lung endothelium targeting for pulmonary embolism thrombolysis. Circulation. 108: 2892-8. PMID 14610017 DOI: 10.1161/01.Cir.0000103685.61137.3D  0.337
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