Year |
Citation |
Score |
2016 |
Certo MT, Morgan RA. Salient Features of Endonuclease Platforms for Therapeutic Genome Editing. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26796671 DOI: 10.1038/mt.2016.21 |
0.588 |
|
2014 |
Metzger MJ, Certo MT. Design and analysis of site-specific single-strand nicking endonucleases for gene correction. Methods in Molecular Biology (Clifton, N.J.). 1114: 237-44. PMID 24557907 DOI: 10.1007/978-1-62703-761-7_15 |
0.553 |
|
2014 |
Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D, Scharenberg AM. MegaTALs: A rare-cleaving nuclease architecture for therapeutic genome engineering Nucleic Acids Research. 42: 2591-2601. PMID 24285304 DOI: 10.1093/Nar/Gkt1224 |
0.671 |
|
2014 |
Kuhar R, Gwiazda KS, Humbert O, Mandt T, Pangallo J, Brault M, Khan I, Maizels N, Rawlings DJ, Scharenberg AM, Certo MT. Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks. Nucleic Acids Research. 42: e4. PMID 24121685 DOI: 10.1093/Nar/Gkt872 |
0.717 |
|
2012 |
Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, et al. Coupling endonucleases with DNA end-processing enzymes to drive gene disruption. Nature Methods. 9: 973-5. PMID 22941364 DOI: 10.1038/Nmeth.2177 |
0.579 |
|
2012 |
Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK. Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects. Nucleic Acids Research. 40: 5560-8. PMID 22373919 DOI: 10.1093/Nar/Gks179 |
0.711 |
|
2012 |
Jacoby K, Metzger M, Shen BW, Certo MT, Jarjour J, Stoddard BL, Scharenberg AM. Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space. Nucleic Acids Research. 40: 4954-64. PMID 22334611 DOI: 10.1093/Nar/Gkr1303 |
0.697 |
|
2011 |
Certo MT, Ryu BY, Annis JE, Garibov M, Jarjour J, Rawlings DJ, Scharenberg AM. Tracking genome engineering outcome at individual DNA breakpoints. Nature Methods. 8: 671-6. PMID 21743461 DOI: 10.1038/nmeth.1648 |
0.679 |
|
2009 |
Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM. High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display. Nucleic Acids Research. 37: 6871-80. PMID 19740766 DOI: 10.1093/Nar/Gkp726 |
0.698 |
|
2009 |
Takeuchi R, Certo M, Caprara MG, Scharenberg AM, Stoddard BL. Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation. Nucleic Acids Research. 37: 877-90. PMID 19103658 DOI: 10.1093/Nar/Gkn1007 |
0.636 |
|
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