Robert Sharpe - Publications
Affiliations: | 2010-2015 | Chemistry | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Year | Citation | Score | |||
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2017 | Good SN, Sharpe RJ, Johnson JS. Highly Functionalized Tricyclic Oxazinanones via Pairwise Oxidative Dearomatization and N-Hydroxycarbamate Dehydrogenation: Molecular Diversity Inspired by Tetrodotoxin. Journal of the American Chemical Society. PMID 28853553 DOI: 10.1021/Jacs.7B07745 | 0.561 | |||
2015 | Sharpe RJ, Portillo M, Vélez RA, Johnson JS. A Scalable Protocol for the Regioselective Alkylation of 2-Methylcyclohexane-1,3-dione with Unactivated sp(3) Electrophiles. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 26: 2293-2295. PMID 26525231 DOI: 10.1055/S-0035-1560186 | 0.592 | |||
2015 | Sharpe RJ, Johnson JS. Asymmetric Total Synthesis of the Indole Diterpene Alkaloid Paspaline. The Journal of Organic Chemistry. PMID 26398568 DOI: 10.1021/Acs.Joc.5B01844 | 0.657 | |||
2015 | Sharpe RJ, Johnson JS. A global and local desymmetrization approach to the synthesis of steroidal alkaloids: stereocontrolled total synthesis of paspaline. Journal of the American Chemical Society. 137: 4968-71. PMID 25856767 DOI: 10.1021/Jacs.5B02631 | 0.642 | |||
2015 | Sharpe RJ, Malinowski JT, Sorana F, Luft JC, Bowerman CJ, DeSimone JM, Johnson JS. Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity. Bioorganic & Medicinal Chemistry. 23: 1849-57. PMID 25792144 DOI: 10.1016/J.Bmc.2015.02.022 | 0.604 | |||
2013 | Sharpe RJ, Malinowski JT, Johnson JS. Asymmetric synthesis of the aminocyclitol pactamycin, a universal translocation inhibitor. Journal of the American Chemical Society. 135: 17990-8. PMID 24245656 DOI: 10.1021/Ja409944U | 0.624 | |||
2013 | Malinowski JT, Sharpe RJ, Johnson JS. Enantioselective synthesis of pactamycin, a complex antitumor antibiotic. Science (New York, N.Y.). 340: 180-2. PMID 23580525 DOI: 10.1126/Science.1234756 | 0.631 | |||
2011 | Sharpe RJ, Jennings MP. A formal synthesis of (-)-cyanolide A featuring a stereoselective Mukaiyama aldol reaction and oxocarbenium reduction. The Journal of Organic Chemistry. 76: 8027-32. PMID 21863875 DOI: 10.1021/Jo201210U | 0.467 | |||
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