Robert Sharpe - Publications

Affiliations: 
2010-2015 Chemistry University of North Carolina, Chapel Hill, Chapel Hill, NC 

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Good SN, Sharpe RJ, Johnson JS. Highly Functionalized Tricyclic Oxazinanones via Pairwise Oxidative Dearomatization and N-Hydroxycarbamate Dehydrogenation: Molecular Diversity Inspired by Tetrodotoxin. Journal of the American Chemical Society. PMID 28853553 DOI: 10.1021/Jacs.7B07745  0.561
2015 Sharpe RJ, Portillo M, Vélez RA, Johnson JS. A Scalable Protocol for the Regioselective Alkylation of 2-Methylcyclohexane-1,3-dione with Unactivated sp(3) Electrophiles. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 26: 2293-2295. PMID 26525231 DOI: 10.1055/S-0035-1560186  0.592
2015 Sharpe RJ, Johnson JS. Asymmetric Total Synthesis of the Indole Diterpene Alkaloid Paspaline. The Journal of Organic Chemistry. PMID 26398568 DOI: 10.1021/Acs.Joc.5B01844  0.657
2015 Sharpe RJ, Johnson JS. A global and local desymmetrization approach to the synthesis of steroidal alkaloids: stereocontrolled total synthesis of paspaline. Journal of the American Chemical Society. 137: 4968-71. PMID 25856767 DOI: 10.1021/Jacs.5B02631  0.642
2015 Sharpe RJ, Malinowski JT, Sorana F, Luft JC, Bowerman CJ, DeSimone JM, Johnson JS. Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity. Bioorganic & Medicinal Chemistry. 23: 1849-57. PMID 25792144 DOI: 10.1016/J.Bmc.2015.02.022  0.604
2013 Sharpe RJ, Malinowski JT, Johnson JS. Asymmetric synthesis of the aminocyclitol pactamycin, a universal translocation inhibitor. Journal of the American Chemical Society. 135: 17990-8. PMID 24245656 DOI: 10.1021/Ja409944U  0.624
2013 Malinowski JT, Sharpe RJ, Johnson JS. Enantioselective synthesis of pactamycin, a complex antitumor antibiotic. Science (New York, N.Y.). 340: 180-2. PMID 23580525 DOI: 10.1126/Science.1234756  0.631
2011 Sharpe RJ, Jennings MP. A formal synthesis of (-)-cyanolide A featuring a stereoselective Mukaiyama aldol reaction and oxocarbenium reduction. The Journal of Organic Chemistry. 76: 8027-32. PMID 21863875 DOI: 10.1021/Jo201210U  0.467
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