Samie R. Jaffrey, M.D., Ph.D. - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Kim JY, Deglincerti A, Jaffrey SR. A Staufen1-mediated decay pathway influences the local transcriptome in axons. Translation (Austin, Tex.). 5: e1414016. PMID 29416957 DOI: 10.1080/21690731.2017.1414016  0.32
2016 Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, Linder B, Pickering BF, Vasseur JJ, Chen Q, Gross SS, Elemento O, Debart F, Kiledjian M, Jaffrey SR. Reversible methylation of m(6)Am in the 5' cap controls mRNA stability. Nature. PMID 28002401 DOI: 10.1038/nature21022  0.36
2016 Yang WY, He F, Strack RL, Oh SY, Frazer M, Jaffrey SR, Todd PK, Disney MD. Small Molecule Recognition and Tools to Study Modulation of r(CGG)exp in Fragile X-Associated Tremor Ataxia Syndrome. Acs Chemical Biology. PMID 27276216 DOI: 10.1021/acschembio.6b00147  1
2016 Frye M, Jaffrey SR, Pan T, Rechavi G, Suzuki T. RNA modifications: what have we learned and where are we headed? Nature Reviews. Genetics. PMID 27140282 DOI: 10.1038/nrg.2016.47  1
2016 Meyer KD, Jaffrey SR. Expanding the diversity of DNA base modifications with N (6)-methyldeoxyadenosine. Genome Biology. 17: 5. PMID 26762117 DOI: 10.1186/s13059-016-0874-7  1
2015 Meyer KD, Patil DP, Zhou J, Zinoviev A, Skabkin MA, Elemento O, Pestova TV, Qian SB, Jaffrey SR. 5' UTR m(6)A Promotes Cap-Independent Translation. Cell. 163: 999-1010. PMID 26593424 DOI: 10.1016/j.cell.2015.10.012  1
2015 Zhou J, Wan J, Gao X, Zhang X, Jaffrey SR, Qian SB. Dynamic m(6)A mRNA methylation directs translational control of heat shock response. Nature. PMID 26458103 DOI: 10.1038/nature15377  1
2015 Miyawaki A, Jaffrey SR. Editorial overview: Molecular imaging: Cellular imaging approaches. Current Opinion in Chemical Biology. 27: v-vi. PMID 26238588 DOI: 10.1016/j.cbpa.2015.07.004  1
2015 Liu Y, Huang X, He X, Zhou Y, Jiang X, Chen-Kiang S, Jaffrey SR, Xu G. A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26231201 DOI: 10.1096/fj.15-274050  0.32
2015 Lu Z, Filonov GS, Noto JJ, Schmidt CA, Hatkevich TL, Wen Y, Jaffrey SR, Matera AG. Metazoan tRNA introns generate stable circular RNAs in vivo. Rna (New York, N.Y.). PMID 26194134 DOI: 10.1261/rna.052944.115  1
2015 You M, Jaffrey SR. Structure and Mechanism of RNA Mimics of Green Fluorescent Protein. Annual Review of Biophysics. 44: 187-206. PMID 26098513 DOI: 10.1146/annurev-biophys-060414-033954  1
2015 Filonov GS, Kam CW, Song W, Jaffrey SR. In-gel imaging of RNA processing using broccoli reveals optimal aptamer expression strategies. Chemistry & Biology. 22: 649-60. PMID 26000751 DOI: 10.1016/j.chembiol.2015.04.018  1
2015 You M, Litke JL, Jaffrey SR. Imaging metabolite dynamics in living cells using a Spinach-based riboswitch. Proceedings of the National Academy of Sciences of the United States of America. 112: E2756-65. PMID 25964329 DOI: 10.1073/pnas.1504354112  1
2015 Deglincerti A, Liu Y, Colak D, Hengst U, Xu G, Jaffrey SR. Coupled local translation and degradation regulate growth cone collapse. Nature Communications. 6: 6888. PMID 25901863 DOI: 10.1038/ncomms7888  1
2015 You M, Jaffrey SR. Designing optogenetically controlled RNA for regulating biological systems. Annals of the New York Academy of Sciences. PMID 25758022 DOI: 10.1111/nyas.12660  1
2015 Strack RL, Jaffrey SR. Live-cell imaging of mammalian RNAs with Spinach2. Methods in Enzymology. 550: 129-46. PMID 25605384 DOI: 10.1016/bs.mie.2014.10.044  1
2014 Brown KD, Maqsood S, Huang JY, Pan Y, Harkcom W, Li W, Sauve A, Verdin E, Jaffrey SR. Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss. Cell Metabolism. 20: 1059-68. PMID 25470550 DOI: 10.1016/j.cmet.2014.11.003  1
2014 Jaffrey SR. An expanding universe of mRNA modifications. Nature Structural & Molecular Biology. 21: 945-6. PMID 25372308 DOI: 10.1038/nsmb.2911  1
2014 Filonov GS, Moon JD, Svensen N, Jaffrey SR. Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based selection and directed evolution. Journal of the American Chemical Society. 136: 16299-308. PMID 25337688 DOI: 10.1021/ja508478x  1
2014 Warner KD, Chen MC, Song W, Strack RL, Thorn A, Jaffrey SR, Ferré-D'Amaré AR. Structural basis for activity of highly efficient RNA mimics of green fluorescent protein. Nature Structural & Molecular Biology. 21: 658-63. PMID 25026079 DOI: 10.1038/nsmb.2865  1
2014 Xu G, Deglincerti A, Paige JS, Jaffrey SR. Profiling lysine ubiquitination by selective enrichment of ubiquitin remnant-containing peptides. Methods in Molecular Biology (Clifton, N.J.). 1174: 57-71. PMID 24947374 DOI: 10.1007/978-1-4939-0944-5_4  1
2014 Harkcom WT, Ghosh AK, Sung MS, Matov A, Brown KD, Giannakakou P, Jaffrey SR. NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents. Proceedings of the National Academy of Sciences of the United States of America. 111: E2443-52. PMID 24889606 DOI: 10.1073/pnas.1404269111  1
2014 Meyer KD, Jaffrey SR. The dynamic epitranscriptome: N6-methyladenosine and gene expression control. Nature Reviews. Molecular Cell Biology. 15: 313-26. PMID 24713629 DOI: 10.1038/nrm3785  1
2014 Colak D, Zaninovic N, Cohen MS, Rosenwaks Z, Yang WY, Gerhardt J, Disney MD, Jaffrey SR. Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome. Science (New York, N.Y.). 343: 1002-5. PMID 24578575 DOI: 10.1126/science.1245831  1
2014 Lundquist MR, Storaska AJ, Liu TC, Larsen SD, Evans T, Neubig RR, Jaffrey SR. Redox modification of nuclear actin by MICAL-2 regulates SRF signaling. Cell. 156: 563-76. PMID 24440334 DOI: 10.1016/j.cell.2013.12.035  1
2014 Song W, Strack RL, Svensen N, Jaffrey SR. Plug-and-play fluorophores extend the spectral properties of Spinach. Journal of the American Chemical Society. 136: 1198-201. PMID 24393009 DOI: 10.1021/ja410819x  1
2014 Strack RL, Song W, Jaffrey SR. Using Spinach-based sensors for fluorescence imaging of intracellular metabolites and proteins in living bacteria. Nature Protocols. 9: 146-55. PMID 24356773 DOI: 10.1038/nprot.2014.001  1
2014 Gerhardt J, Tomishima MJ, Zaninovic N, Colak D, Yan Z, Zhan Q, Rosenwaks Z, Jaffrey SR, Schildkraut CL. The DNA replication program is altered at the FMR1 locus in fragile X embryonic stem cells. Molecular Cell. 53: 19-31. PMID 24289922 DOI: 10.1016/j.molcel.2013.10.029  1
2014 Ji SJ, Jaffrey SR. Axonal transcription factors: novel regulators of growth cone-to-nucleus signaling. Developmental Neurobiology. 74: 245-58. PMID 23897628 DOI: 10.1002/dneu.22112  1
2014 Strack RL, Jaffrey SR. Using RNA Mimics of GFP to Image RNA Dynamics in Mammalian Cells Fluorescence Microscopy: Super-Resolution and Other Novel Techniques. 83-91. DOI: 10.1016/B978-0-12-409513-7.00006-3  1
2013 Xu G, Jaffrey SR. Proteomic identification of protein ubiquitination events. Biotechnology & Genetic Engineering Reviews. 29: 73-109. PMID 24568254 DOI: 10.1080/02648725.2013.801232  1
2013 Strack RL, Disney MD, Jaffrey SR. A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat-containing RNA. Nature Methods. 10: 1219-24. PMID 24162923 DOI: 10.1038/nmeth.2701  1
2013 Curanovic D, Cohen M, Singh I, Slagle CE, Leslie CS, Jaffrey SR. Global profiling of stimulus-induced polyadenylation in cells using a poly(A) trap. Nature Chemical Biology. 9: 671-3. PMID 23995769 DOI: 10.1038/nchembio.1334  1
2013 Xu G, Jiang X, Jaffrey SR. A mental retardation-linked nonsense mutation in cereblon is rescued by proteasome inhibition. The Journal of Biological Chemistry. 288: 29573-85. PMID 23983124 DOI: 10.1074/jbc.M113.472092  1
2013 Song W, Strack RL, Jaffrey SR. Imaging bacterial protein expression using genetically encoded RNA sensors. Nature Methods. 10: 873-5. PMID 23872791 DOI: 10.1038/nmeth.2568  1
2013 Hess ME, Hess S, Meyer KD, Verhagen LA, Koch L, Brönneke HS, Dietrich MO, Jordan SD, Saletore Y, Elemento O, Belgardt BF, Franz T, Horvath TL, Rüther U, Jaffrey SR, et al. The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nature Neuroscience. 16: 1042-8. PMID 23817550 DOI: 10.1038/nn.3449  1
2013 Colak D, Ji SJ, Porse BT, Jaffrey SR. Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay. Cell. 153: 1252-65. PMID 23746841 DOI: 10.1016/j.cell.2013.04.056  1
2013 Strack RL, Jaffrey SR. New approaches for sensing metabolites and proteins in live cells using RNA. Current Opinion in Chemical Biology. 17: 651-5. PMID 23746618 DOI: 10.1016/j.cbpa.2013.05.014  1
2013 Xu G, Jaffrey SR. Comprehensive profiling of protein ubiquitination for drug discovery. Current Pharmaceutical Design. 19: 3315-28. PMID 23151132 DOI: 10.2174/13816128113199990305  1
2012 Saletore Y, Meyer K, Korlach J, Vilfan ID, Jaffrey S, Mason CE. The birth of the Epitranscriptome: deciphering the function of RNA modifications. Genome Biology. 13: 175. PMID 23113984 DOI: 10.1186/gb-2012-13-10-175  1
2012 Walker BA, Ji SJ, Jaffrey SR. Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14442-7. PMID 23055514 DOI: 10.1523/JNEUROSCI.0176-12.2012  1
2012 Deglincerti A, Jaffrey SR. Insights into the roles of local translation from the axonal transcriptome. Open Biology. 2: 120079. PMID 22773949 DOI: 10.1098/rsob.120079  1
2012 Meyer KD, Saletore Y, Zumbo P, Elemento O, Mason CE, Jaffrey SR. Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell. 149: 1635-46. PMID 22608085 DOI: 10.1016/j.cell.2012.05.003  1
2012 Ji SJ, Jaffrey SR. Intra-axonal translation of SMAD1/5/8 mediates retrograde regulation of trigeminal ganglia subtype specification. Neuron. 74: 95-107. PMID 22500633 DOI: 10.1016/j.neuron.2012.02.022  1
2012 Paige JS, Nguyen-Duc T, Song W, Jaffrey SR. Fluorescence imaging of cellular metabolites with RNA. Science (New York, N.Y.). 335: 1194. PMID 22403384 DOI: 10.1126/science.1218298  1
2012 Cohen MS, Ghosh AK, Kim HJ, Jeon NL, Jaffrey SR. Chemical genetic-mediated spatial regulation of protein expression in neurons reveals an axonal function for wld(s). Chemistry & Biology. 19: 179-87. PMID 22365601 DOI: 10.1016/j.chembiol.2012.01.012  1
2012 Walker BA, Hengst U, Kim HJ, Jeon NL, Schmidt EF, Heintz N, Milner TA, Jaffrey SR. Reprogramming axonal behavior by axon-specific viral transduction. Gene Therapy. 19: 947-55. PMID 22278412 DOI: 10.1038/gt.2011.217  1
2012 Baeza JL, de la Torre BG, Santiveri CM, Almeida RD, García-López MT, Gerona-Navarro G, Jaffrey SR, Jiménez MÁ, Andreu D, González-Muñiz R, Martín-Martínez M. Cyclic amino acid linkers stabilizing key loops of brain derived neurotrophic factor. Bioorganic & Medicinal Chemistry Letters. 22: 444-8. PMID 22119467 DOI: 10.1016/j.bmcl.2011.10.107  1
2012 Saletore Y, Meyer K, Korlach J, Vilfan ID, Jaffrey S, Mason CE. The birth of the Epitranscriptome: Deciphering the function of RNA modifications Genome Biology. 175. DOI: 10.1186/gb4056  1
2011 Xu G, Jaffrey SR. The new landscape of protein ubiquitination. Nature Biotechnology. 29: 1098-100. PMID 22158364 DOI: 10.1038/nbt.2061  1
2011 Xu G, Shin SB, Jaffrey SR. Chemoenzymatic labeling of protein C-termini for positive selection of C-terminal peptides. Acs Chemical Biology. 6: 1015-20. PMID 21812462 DOI: 10.1021/cb200164h  1
2011 Paige JS, Wu KY, Jaffrey SR. RNA mimics of green fluorescent protein. Science (New York, N.Y.). 333: 642-6. PMID 21798953 DOI: 10.1126/science.1207339  1
2011 Cohen MS, Bas Orth C, Kim HJ, Jeon NL, Jaffrey SR. Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites. Proceedings of the National Academy of Sciences of the United States of America. 108: 11246-51. PMID 21690335 DOI: 10.1073/pnas.1012401108  1
2010 Shin SB, Almeida RD, Gerona-Navarro G, Bracken C, Jaffrey SR. Assembling ligands in situ using bioorthogonal boronate ester synthesis. Chemistry & Biology. 17: 1171-6. PMID 21095566 DOI: 10.1016/j.chembiol.2010.09.008  1
2010 Xu G, Jaffrey SR. N-CLAP: global profiling of N-termini by chemoselective labeling of the alpha-amine of proteins. Cold Spring Harbor Protocols. 2010: pdb.prot5528. PMID 21041401  0.32
2010 Xu G, Paige JS, Jaffrey SR. Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nature Biotechnology. 28: 868-73. PMID 20639865 DOI: 10.1038/nbt.1654  1
2010 Xu G, Jaffrey SR. N-CLAP: Global profiling of N-termini by chemoselective labeling of the α-graphic amine of proteins Cold Spring Harbor Protocols. 5. DOI: 10.1101/pdb.prot5528  1
2009 Xu G, Shin SB, Jaffrey SR. Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini. Proceedings of the National Academy of Sciences of the United States of America. 106: 19310-5. PMID 19892738 DOI: 10.1073/pnas.0908958106  1
2009 Rivieccio MA, Brochier C, Willis DE, Walker BA, D'Annibale MA, McLaughlin K, Siddiq A, Kozikowski AP, Jaffrey SR, Twiss JL, Ratan RR, Langley B. HDAC6 is a target for protection and regeneration following injury in the nervous system. Proceedings of the National Academy of Sciences of the United States of America. 106: 19599-604. PMID 19884510 DOI: 10.1073/pnas.0907935106  1
2009 Hengst U, Deglincerti A, Kim HJ, Jeon NL, Jaffrey SR. Axonal elongation triggered by stimulus-induced local translation of a polarity complex protein. Nature Cell Biology. 11: 1024-30. PMID 19620967 DOI: 10.1038/ncb1916  1
2008 Paige JS, Xu G, Stancevic B, Jaffrey SR. Nitrosothiol reactivity profiling identifies S-nitrosylated proteins with unexpected stability. Chemistry & Biology. 15: 1307-16. PMID 19101475 DOI: 10.1016/j.chembiol.2008.10.013  1
2008 Cox LJ, Hengst U, Gurskaya NG, Lukyanov KA, Jaffrey SR. Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival. Nature Cell Biology. 10: 149-59. PMID 18193038 DOI: 10.1038/ncb1677  1
2007 Hengst U, Jaffrey SR. Function and translational regulation of mRNA in developing axons. Seminars in Cell & Developmental Biology. 18: 209-15. PMID 17478114 DOI: 10.1016/j.semcdb.2007.01.003  1
2007 Paige JS, Jaffrey SR. Pharmacologic manipulation of nitric oxide signaling: targeting NOS dimerization and protein-protein interactions. Current Topics in Medicinal Chemistry. 7: 97-114. PMID 17266598 DOI: 10.2174/156802607779318253  1
2006 Wu KY, Zippin JH, Huron DR, Kamenetsky M, Hengst U, Buck J, Levin LR, Jaffrey SR. Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nature Neuroscience. 9: 1257-64. PMID 16964251 DOI: 10.1038/nn1767  1
2006 Hengst U, Cox LJ, Macosko EZ, Jaffrey SR. Functional and selective RNA interference in developing axons and growth cones. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5727-32. PMID 16723529 DOI: 10.1523/JNEUROSCI.5229-05.2006  1
2005 Jaffrey SR. Detection and characterization of protein nitrosothiols. Methods in Enzymology. 396: 105-18. PMID 16291226 DOI: 10.1016/S0076-6879(05)96011-4  1
2005 Wu KY, Hengst U, Cox LJ, Macosko EZ, Jeromin A, Urquhart ER, Jaffrey SR. Local translation of RhoA regulates growth cone collapse. Nature. 436: 1020-4. PMID 16107849 DOI: 10.1038/nature03885  1
2005 He XG, Gerona-Navarro G, Jaffrey SR. Ligand discovery using small molecule microarrays. The Journal of Pharmacology and Experimental Therapeutics. 313: 1-7. PMID 15537823 DOI: 10.1124/jpet.104.076943  1
2002 Jaffrey SR, Fang M, Snyder SH. Nitrosopeptide mapping: a novel methodology reveals s-nitrosylation of dexras1 on a single cysteine residue. Chemistry & Biology. 9: 1329-35. PMID 12498886 DOI: 10.1016/S1074-5521(02)00293-4  1
2002 Jaffrey SR, Benfenati F, Snowman AM, Czernik AJ, Snyder SH. Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. Proceedings of the National Academy of Sciences of the United States of America. 99: 3199-204. PMID 11867766 DOI: 10.1073/pnas.261705799  1
2001 Jaffrey SR, Snyder SH. The biotin switch method for the detection of S-nitrosylated proteins. Science's Stke : Signal Transduction Knowledge Environment. 2001: pl1. PMID 11752655 DOI: 10.1126/stke.2001.86.pl1  1
2001 Jaffrey SR, Erdjument-Bromage H, Ferris CD, Tempst P, Snyder SH. Protein S-nitrosylation: a physiological signal for neuronal nitric oxide. Nature Cell Biology. 3: 193-7. PMID 11175752 DOI: 10.1038/35055104  1
2000 Fang M, Jaffrey SR, Sawa A, Ye K, Luo X, Snyder SH. Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Neuron. 28: 183-93. PMID 11086993  1
2000 Watkins CC, Sawa A, Jaffrey S, Blackshaw S, Barrow RK, Snyder SH, Ferris CD. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy. The Journal of Clinical Investigation. 106: 373-84. PMID 10930440 DOI: 10.1172/JCI8273  1
1999 Snyder SH, Jaffrey SR. Vessels vivified by Akt acting on NO synthase. Nature Cell Biology. 1: E95-6. PMID 10559931 DOI: 10.1038/12093  1
1999 Ferris CD, Jaffrey SR, Sawa A, Takahashi M, Brady SD, Barrow RK, Tysoe SA, Wolosker H, Barañano DE, Doré S, Poss KD, Snyder SH. Haem oxygenase-1 prevents cell death by regulating cellular iron. Nature Cell Biology. 1: 152-7. PMID 10559901 DOI: 10.1038/11072  1
1999 Liang J, Jaffrey SR, Guo W, Snyder SH, Clardy J. Structure of the PIN/LC8 dimer with a bound peptide. Nature Structural Biology. 6: 735-40. PMID 10426949 DOI: 10.1038/11501  1
1998 Snyder SH, Jaffrey SR, Zakhary R. Nitric oxide and carbon monoxide: parallel roles as neural messengers. Brain Research. Brain Research Reviews. 26: 167-75. PMID 9651518 DOI: 10.1016/S0165-0173(97)00032-5  1
1998 Jaffrey SR, Snowman AM, Eliasson MJ, Cohen NA, Snyder SH. CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. Neuron. 20: 115-24. PMID 9459447 DOI: 10.1016/S0896-6273(00)80439-0  1
1997 Zakhary R, Poss KD, Jaffrey SR, Ferris CD, Tonegawa S, Snyder SH. Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide. Proceedings of the National Academy of Sciences of the United States of America. 94: 14848-53. PMID 9405702 DOI: 10.1073/pnas.94.26.14848  1
1996 Jaffrey SR, Snyder SH. PIN: an associated protein inhibitor of neuronal nitric oxide synthase. Science (New York, N.Y.). 274: 774-7. PMID 8864115 DOI: 10.1126/science.274.5288.774  1
1995 Jaffrey SR, Snyder SH. Nitric oxide: a neural messenger. Annual Review of Cell and Developmental Biology. 11: 417-40. PMID 8689564 DOI: 10.1146/annurev.cb.11.110195.002221  1
1994 Jaffrey SR, Cohen NA, Rouault TA, Klausner RD, Snyder SH. The iron-responsive element binding protein: a target for synaptic actions of nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 91: 12994-8. PMID 7809162 DOI: 10.1073/pnas.91.26.12994  1
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