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Krista Spiller - Publications

Affiliations: 
2006-2009 NIH/NIDA, Rockville, MD, United States 
 2009-2013 Neurobiology and Behavior Columbia University, New York, NY 
 2014- University of Pennsylvania, Philadelphia, PA, United States 
Area:
motor neuron diversity, neurodegeneration, glia, neuroregeneration

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Spiller KJ, Bi GH, He Y, Galaj E, Gardner EL, Xi ZX. Cannabinoid CB and CB receptor mechanisms underlie cannabis reward and aversion in rats. British Journal of Pharmacology. PMID 30767215 DOI: 10.1111/bph.14625  1
2018 Spiller KJ, Khan T, Dominique MA, Restrepo CR, Cotton-Samuel D, Levitan M, Jafar-Nejad P, Zhang B, Soriano A, Rigo F, Trojanowski JQ, Lee VM. Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice. Neurobiology of Disease. PMID 30458231 DOI: 10.1016/j.nbd.2018.11.013  1
2018 Thams S, Lowry ER, Larraufie MH, Spiller KJ, Li H, Williams DJ, Hoang P, Jiang E, Williams LA, Sandoe J, Eggan K, Lieberam I, Kanning KC, Stockwell BR, Henderson CE, et al. A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30446391 DOI: 10.1016/j.ymthe.2018.10.010  1
2018 Spiller KJ, Restrepo CR, Khan T, Dominique MA, Fang TC, Canter RG, Roberts CJ, Miller KR, Ransohoff RM, Trojanowski JQ, Lee VM. Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy. Nature Neuroscience. PMID 29463850 DOI: 10.1038/s41593-018-0083-7  1
2016 Spiller KJ, Restrepo CR, Khan T, Stieber AM, Kwong LK, Trojanowski JQ, Lee VM. Progression of motor neuron disease is accelerated and the ability to recover is compromised with advanced age in rNLS8 mice. Acta Neuropathologica Communications. 4: 105. PMID 27687289 DOI: 10.1186/s40478-016-0377-5  1
2016 Spiller KJ, Cheung CJ, Restrepo CR, Kwong LK, Stieber AM, Trojanowski JQ, Lee VM. Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7707-17. PMID 27445147 DOI: 10.1523/JNEUROSCI.1457-16.2016  1
2015 Walker AK, Spiller KJ, Ge G, Zheng A, Xu Y, Zhou M, Tripathy K, Kwong LK, Trojanowski JQ, Lee VM. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43. Acta Neuropathologica. PMID 26197969 DOI: 10.1007/s00401-015-1460-x  1
2014 Kaplan A, Spiller KJ, Towne C, Kanning KC, Choe GT, Geber A, Akay T, Aebischer P, Henderson CE. Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration. Neuron. 81: 333-48. PMID 24462097 DOI: 10.1016/j.neuron.2013.12.009  1
2011 Higley AE, Spiller K, Grundt P, Newman AH, Kiefer SW, Xi ZX, Gardner EL. PG01037, a novel dopamine D3 receptor antagonist, inhibits the effects of methamphetamine in rats. Journal of Psychopharmacology (Oxford, England). 25: 263-73. PMID 20142301 DOI: 10.1177/0269881109358201  1
2010 Peng XQ, Xi ZX, Li X, Spiller K, Li J, Chun L, Wu KM, Froimowitz M, Gardner EL. Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2564-78. PMID 20827272 DOI: 10.1038/npp.2010.133  1
2010 Xi ZX, Kiyatkin M, Li X, Peng XQ, Wiggins A, Spiller K, Li J, Gardner EL. N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats. Neuropharmacology. 58: 304-13. PMID 19559037 DOI: 10.1016/j.neuropharm.2009.06.016  1
2009 Schneider AM, Simson PE, Spiller K, Adelstein J, Vacharat A, Short KR, Kirby LG. Stress-dependent enhancement and impairment of retention by naloxone: evidence for an endogenous opioid-based modulatory system protective of memory. Behavioural Brain Research. 205: 290-3. PMID 19523491 DOI: 10.1016/j.bbr.2009.06.007  1
2009 Xi ZX, Spiller K, Gardner EL. Mechanism-based medication development for the treatment of nicotine dependence. Acta Pharmacologica Sinica. 30: 723-39. PMID 19434058 DOI: 10.1038/aps.2009.46  1
2009 Spiller K, Xi ZX, Li X, Ashby CR, Callahan PM, Tehim A, Gardner EL. Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of alpha4beta2 nicotinic receptors in rats. Neuropharmacology. 57: 60-6. PMID 19393252 DOI: 10.1016/j.neuropharm.2009.04.006  1
2009 Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX. Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1783-96. PMID 19158667 DOI: 10.1038/npp.2008.236  1
2009 Peng XQ, Ashby CR, Spiller K, Li X, Li J, Thomasson N, Millan MJ, Mocaër E, MuÅ„oz C, Gardner EL, Xi ZX. The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats. Neuropharmacology. 56: 752-60. PMID 19136017 DOI: 10.1016/j.neuropharm.2008.12.007  1
2008 Spiller K, Xi ZX, Peng XQ, Newman AH, Ashby CR, Heidbreder C, Gaál J, Gardner EL. The selective dopamine D3 receptor antagonists SB-277011A and NGB 2904 and the putative partial D3 receptor agonist BP-897 attenuate methamphetamine-enhanced brain stimulation reward in rats. Psychopharmacology. 196: 533-42. PMID 17985117 DOI: 10.1007/s00213-007-0986-6  1
2008 Xi ZX, Spiller K, Pak AC, Gilbert J, Dillon C, Li X, Peng XQ, Gardner EL. Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1735-45. PMID 17728698 DOI: 10.1038/sj.npp.1301552  1
2007 Xi ZX, Yang Z, Li SJ, Li X, Dillon C, Peng XQ, Spiller K, Gardner EL. Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropharmacology. 53: 771-82. PMID 17888459 DOI: 10.1016/j.neuropharm.2007.08.004  1
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