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Scott X. Atwood - Publications

Affiliations: 
2008 University of Oregon, Eugene, OR, United States 
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Guerrero-Juarez CF, Lee GH, Liu Y, Wang S, Karikomi M, Sha Y, Chow RY, Nguyen TTL, Iglesias VS, Aasi S, Drummond ML, Nie Q, Sarin K, Atwood SX. Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment. Science Advances. 8: eabm7981. PMID 35687691 DOI: 10.1126/sciadv.abm7981  0.305
2021 Chow RY, Jeon US, Levee TM, Kaur G, Cedeno DP, Doan LT, Atwood SX. PI3K Promotes Basal Cell Carcinoma Growth Through Kinase-Induced p21 Degradation. Frontiers in Oncology. 11: 668247. PMID 34268113 DOI: 10.3389/fonc.2021.668247  0.389
2020 Chow RY, Levee TM, Kaur G, Cedeno DP, Doan LT, Atwood SX. MTOR promotes basal cell carcinoma growth through atypical PKC. Experimental Dermatology. PMID 33617094 DOI: 10.1111/exd.14255  0.345
2020 Yao CD, Haensel D, Gaddam S, Patel T, Atwood SX, Sarin KY, Whitson RJ, McKellar S, Shankar G, Aasi S, Rieger K, Oro AE. AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma. Nature Communications. 11: 5079. PMID 33033234 DOI: 10.1016/J.Jid.2020.03.143  0.455
2020 Wang S, Drummond ML, Guerrero-Juarez CF, Tarapore E, MacLean AL, Stabell AR, Wu SC, Gutierrez G, That BT, Benavente CA, Nie Q, Atwood SX. Single cell transcriptomics of human epidermis identifies basal stem cell transition states. Nature Communications. 11: 4239. PMID 32843640 DOI: 10.1038/S41467-020-18075-7  0.359
2019 Tarapore E, Atwood SX. Defining the Genetics of Basosquamous Carcinoma. The Journal of Investigative Dermatology. 139: 2258-2260. PMID 31648686 DOI: 10.1016/J.Jid.2019.04.011  0.352
2019 Kuonen F, Huskey NE, Shankar G, Jaju P, Whitson RJ, Rieger KE, Atwood SX, Sarin KY, Oro AE. Loss of primary cilia drives switching from Hedgehog to Ras/MAPK pathway in resistant basal cell carcinoma. The Journal of Investigative Dermatology. PMID 30707899 DOI: 10.1016/J.Jid.2018.11.035  0.409
2019 Lee G, Guerrero-Juarez C, Do H, Aasi S, Nie Q, Sarin K, Atwood S. 154 Dissecting the keratinocyte lineage of basal cell carcinoma using single cell RNA sequencing Journal of Investigative Dermatology. 139: S27. DOI: 10.1016/J.Jid.2019.03.230  0.336
2018 Brown AS, Meera P, Altindag B, Chopra R, Perkins EM, Paul S, Scoles DR, Tarapore E, Magri J, Huang H, Jackson M, Shakkottai VG, Otis TS, Pulst SM, Atwood SX, et al. MTSS1/Src family kinase dysregulation underlies multiple inherited ataxias. Proceedings of the National Academy of Sciences of the United States of America. PMID 30530649 DOI: 10.1073/Pnas.1816177115  0.35
2018 Drummond ML, Li M, Tarapore E, Nguyen TTL, Barouni BJ, Cruz S, Tan KC, Oro AE, Atwood SX. Actin polymerization controls cilia-mediated signaling. The Journal of Cell Biology. PMID 29945904 DOI: 10.1083/Jcb.201703196  0.397
2018 Nguyen TTL, Atwood SX. Illuminating Alternative Strategies to Treat Targeted Chemotherapy-Resistant Sporadic Basal Cell Carcinoma. The Journal of Investigative Dermatology. 138: 1017-1019. PMID 29681387 DOI: 10.1016/J.Jid.2017.11.013  0.384
2018 Whitson RJ, Lee A, Urman NM, Mirza A, Yao CY, Brown AS, Li JR, Shankar G, Fry MA, Atwood SX, Lee EY, Hollmig ST, Aasi SZ, Sarin KY, Scott MP, et al. Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas. Nature Medicine. PMID 29400712 DOI: 10.1038/Nm.4476  0.436
2018 Drummond M, Wang S, MacLean A, Gutierrez G, Nie Q, Atwood S. 1337 Single cell transcriptome profiling of human interfollicular epidermis reveals robust heterogeneity and divergent differentiation lineages Journal of Investigative Dermatology. 138: S227. DOI: 10.1016/J.Jid.2018.03.1354  0.326
2017 Mirza AN, Fry MA, Urman NM, Atwood SX, Roffey J, Ott GR, Chen B, Lee A, Brown AS, Aasi SZ, Hollmig T, Ator MA, Dorsey BD, Ruggeri BR, Zificsak CA, et al. Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment. Jci Insight. 2. PMID 29093271 DOI: 10.1172/Jci.Insight.97071  0.377
2017 Drummond ML, Atwood SX. sm"FISH"ing for Hedgehog. The Journal of Investigative Dermatology. 137: 13-15. PMID 28010757 DOI: 10.1016/J.Jid.2016.07.021  0.334
2016 Urman NM, Mirza A, Atwood SX, Whitson RJ, Sarin KY, Tang JY, Oro AE. Tumor-Derived Suppressor of Fused Mutations Reveal Hedgehog Pathway Interactions. Plos One. 11: e0168031. PMID 28030567 DOI: 10.1371/Journal.Pone.0168031  0.373
2016 Ally MS, Ransohoff K, Sarin K, Atwood SX, Rezaee M, Bailey-Healy I, Kim J, Beachy PA, Chang AL, Oro A, Tang JY, Colevas AD. Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma. Jama Dermatology. 1-5. PMID 26765315 DOI: 10.1001/Jamadermatol.2015.5473  0.392
2016 Whitson R, Lee A, Urman N, Li J, Mirza A, Brown A, Yao C, Shankar G, Fry M, Atwood S, Epstein E, Tang J, Oro A. 081 Resistant basal cell carcinomas require SRF/MRTF to maintain hedgehog pathway activation and tumor growth Journal of Investigative Dermatology. 136: S15. DOI: 10.1016/J.Jid.2016.02.107  0.427
2015 Zhao X, Ponomaryov T, Ornell KJ, Zhou P, Dabral SK, Pak E, Li W, Atwood SX, Whitson RJ, Chang AL, Li J, Oro AE, Chan JA, Kelleher JF, Segal RA. RAS/MAPK activation drives resistance to Smo inhibition, metastasis and tumor evolution in Shh pathway-dependent tumors. Cancer Research. PMID 26130651 DOI: 10.1158/0008-5472.Can-14-2999-T  0.404
2015 Atwood SX, Sarin KY, Li JR, Yao CY, Urman NM, Chang AL, Tang JY, Oro AE. Rolling the Genetic Dice: Neutral and Deleterious Smoothened Mutations in Drug-Resistant Basal Cell Carcinoma. The Journal of Investigative Dermatology. 135: 2138-41. PMID 25801792 DOI: 10.1038/Jid.2015.115  0.376
2015 Atwood SX, Sarin KY, Whitson RJ, Li JR, Kim G, Rezaee M, Ally MS, Kim J, Yao C, Chang AL, Oro AE, Tang JY. Smoothened variants explain the majority of drug resistance in basal cell carcinoma. Cancer Cell. 27: 342-53. PMID 25759020 DOI: 10.1016/J.Ccell.2015.02.002  0.412
2014 Atwood SX, Whitson RJ, Oro AE. Advanced treatment for basal cell carcinomas. Cold Spring Harbor Perspectives in Medicine. 4: a013581. PMID 24985127 DOI: 10.1101/Cshperspect.A013581  0.381
2014 Tang Y, Gholamin S, Schubert S, Willardson MI, Lee A, Bandopadhayay P, Bergthold G, Masoud S, Nguyen B, Vue N, Balansay B, Yu F, Oh S, Woo P, Chen S, ... ... Atwood SX, et al. Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition. Nature Medicine. 20: 732-40. PMID 24973920 DOI: 10.1038/Nm.3613  0.428
2014 Atwood SX, Oro AE. "Atypical" regulation of Hedgehog-dependent cancers. Cancer Cell. 25: 133-4. PMID 24525228 DOI: 10.1016/J.Ccr.2014.01.027  0.343
2014 Tang Y, Schubert S, Qi J, Nguyen B, Masoud S, Vue N, Balansay B, Yu F, Atwood SX, Whitson RJ, Ponnuswami A, Chen S, Gholamin S, Pamelyn WJ, Monje-Diesseroth M, et al. Abstract B6: Epigenetic regulation of Hedgehog pathway transcriptional output by BET bromodomain proteins Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-B6  0.428
2014 Cho Y, Tang Y, Schubert S, Willardson M, Bandopadhayay P, Bergthold G, Nguyen B, Masoud S, Vue N, Balansay B, Gholamin S, Cheshier SH, Atwood SX, Whitson RJ, Lee A, et al. EPIGENETIC TARGETING OF HEDGEHOG PATHWAY TRANSCRIPTIONAL OUTPUT Neuro-Oncology. 16: iii25-iii25. DOI: 10.1093/Neuonc/Nou208.9  0.441
2013 Chang AL, Atwood SX, Tartar DM, Oro AE. Surgical excision after neoadjuvant therapy with vismodegib for a locally advanced basal cell carcinoma and resistant basal carcinomas in Gorlin syndrome. Jama Dermatology. 149: 639-41. PMID 23677114 DOI: 10.1001/Jamadermatol.2013.30  0.331
2013 Atwood SX, Whitson RJ, Oro AE. "Patch"ing up our tumor signaling knowledge. The Journal of Investigative Dermatology. 133: 1131-3. PMID 23594533 DOI: 10.1038/Jid.2012.506  0.414
2013 Woo WM, Atwood SX, Zhen HH, Oro AE. Rapid genetic analysis of epithelial-mesenchymal signaling during hair regeneration. Journal of Visualized Experiments : Jove. e4344. PMID 23486463 DOI: 10.3791/4344  0.382
2013 Atwood SX, Li M, Lee A, Tang JY, Oro AE. GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas. Nature. 494: 484-8. PMID 23446420 DOI: 10.1038/Nature11889  0.494
2012 Atwood SX, Chang AL, Oro AE. Hedgehog pathway inhibition and the race against tumor evolution. The Journal of Cell Biology. 199: 193-7. PMID 23071148 DOI: 10.1083/Jcb.201207140  0.388
2012 Graybill C, Wee B, Atwood SX, Prehoda KE. Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement. The Journal of Biological Chemistry. 287: 21003-11. PMID 22544755 DOI: 10.1074/Jbc.M112.360495  0.617
2010 Bershteyn M, Atwood SX, Woo WM, Li M, Oro AE. MIM and cortactin antagonism regulates ciliogenesis and hedgehog signaling. Developmental Cell. 19: 270-83. PMID 20708589 DOI: 10.1016/J.Devcel.2010.07.009  0.437
2009 Atwood SX, Prehoda KE. aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division. Current Biology : Cb. 19: 723-9. PMID 19375318 DOI: 10.1016/J.Cub.2009.03.056  0.627
2007 Atwood SX, Chabu C, Penkert RR, Doe CQ, Prehoda KE. Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC. Journal of Cell Science. 120: 3200-6. PMID 17726059 DOI: 10.1242/Jcs.014902  0.639
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