| Year |
Citation |
Score |
| 2022 |
Wu J, Liu X, Wallace Reeser JA, Trimboli AJ, Pecot T, Sizemore GM, Naidu SK, Fernandez SA, Yu L, Hallett M, Park M, Leone GW, Hildreth BE, Ostrowski MC. Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner. Molecular Cancer Research : McR. PMID 35533313 DOI: 10.1158/1541-7786.MCR-21-0960 |
0.304 |
|
| 2020 |
Thies KA, Hammer AM, Hildreth BE, Steck SA, Spehar JM, Kladney RD, Geisler JM, Das M, Russell LO, Bey JF, Bolyard CM, Pilarski R, Trimboli AJ, Cuitiño MC, Koivisto CS, ... ... Ostrowski MC, et al. Stromal platelet-derived growth factor receptor-β signaling promotes breast cancer metastasis in the brain. Cancer Research. PMID 32327406 DOI: 10.1158/0008-5472.Can-19-3731 |
0.423 |
|
| 2020 |
Thies KA, Hammer AM, Steck SA, Das M, Kladney RD, Sizemore ST, Ostrowski MC, Sizemore GM. Abstract P6-06-06: Platelet derived growth factor-b (PDGFB) promotes breast cancer progression Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P6-06-06 |
0.421 |
|
| 2019 |
Thies KA, Lefler JE, Leone G, Ostrowski MC. PTEN in the Stroma. Cold Spring Harbor Perspectives in Medicine. PMID 31427286 DOI: 10.1101/Cshperspect.A036111 |
0.402 |
|
| 2019 |
Bowen C, Ostrowski MC, Leone G, Gelmann EP. Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. Cancer Research. PMID 31213464 DOI: 10.1158/0008-5472.Can-18-4110 |
0.385 |
|
| 2019 |
Cuitiño MC, Pécot T, Sun D, Kladney R, Okano-Uchida T, Shinde N, Saeed R, Perez-Castro AJ, Webb A, Liu T, Bae SI, Clijsters L, Selner N, Coppola V, Timmers C, ... Ostrowski MC, et al. Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. Cell Reports. PMID 31130414 DOI: 10.1016/J.Celrep.2019.05.004 |
0.44 |
|
| 2019 |
Xu L, Fu M, Chen D, Han W, Ostrowski MC, Grossfeld P, Gao P, Ye M. Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition. Bmb Reports. PMID 30670148 DOI: 10.5483/Bmbrep.2019.52.10.206 |
0.309 |
|
| 2018 |
Carey HA, Hildreth BE, Samuvel DJ, Thies KA, Rosol TJ, Toribio RE, Charles JF, Ostrowski MC, Sharma SM. Eomes partners with PU.1 and MITF to Regulate Transcription Factors Critical for osteoclast differentiation. Iscience. 11: 238-245. PMID 30634169 DOI: 10.1016/J.Isci.2018.12.018 |
0.416 |
|
| 2018 |
Jones CE, Hammer AM, Cho Y, Sizemore GM, Cukierman E, Yee LD, Ghadiali SN, Ostrowski MC, Leight JL. Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland. Neoplasia (New York, N.Y.). 21: 132-145. PMID 30550871 DOI: 10.1016/J.Neo.2018.10.010 |
0.395 |
|
| 2018 |
Russell L, Swanner J, Jaime-Ramirez AC, Wang Y, Sprague A, Banasavadi-Siddegowda Y, Yoo JY, Sizemore GM, Kladney R, Zhang J, Lehman NL, Ostrowski MC, Hong B, Caligiuri M, Yu J, et al. PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance. Nature Communications. 9: 5006. PMID 30479334 DOI: 10.1038/S41467-018-07344-1 |
0.376 |
|
| 2018 |
Sizemore ST, Zhang M, Cho JH, Sizemore GM, Hurwitz B, Kaur B, Lehman NL, Ostrowski MC, Robe PA, Miao W, Wang Y, Chakravarti A, Xia F. Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair. Cell Research. PMID 30297868 DOI: 10.1038/S41422-018-0086-7 |
0.343 |
|
| 2018 |
Sizemore GM, Balakrishnan S, Thies KA, Hammer AM, Sizemore ST, Trimboli AJ, Cuitiño MC, Steck SA, Tozbikian G, Kladney RD, Shinde N, Das M, Park D, Majumder S, Krishnan S, ... ... Ostrowski MC, et al. Stromal PTEN determines mammary epithelial response to radiotherapy. Nature Communications. 9: 2783. PMID 30018330 DOI: 10.1038/S41467-018-05266-6 |
0.344 |
|
| 2018 |
Ahirwar DK, Nasser MW, Ouseph MM, Elbaz M, Cuitiño MC, Kladney RD, Varikuti S, Kaul K, Satoskar AR, Ramaswamy B, Zhang X, Ostrowski MC, Leone G, Ganju RK. Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation. Oncogene. PMID 29720724 DOI: 10.1038/S41388-018-0263-7 |
0.4 |
|
| 2018 |
Carey HA, Hildreth BE, Geisler JA, Nickel MC, Cabrera J, Ghosh S, Jiang Y, Yan J, Lee J, Makam S, Young NA, Valiente GR, Jarjour WN, Huang K, Rosol TJ, ... ... Ostrowski MC, et al. Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation. Bone Research. 6: 8. PMID 29619268 DOI: 10.1038/S41413-018-0011-1 |
0.367 |
|
| 2018 |
Sizemore ST, Mohammed R, Sizemore GM, Nowsheen S, Yu H, Ostrowski MC, Chakravarti A, Xia F. Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent. Molecular Cancer Research : McR. PMID 29592899 DOI: 10.1158/1541-7786.Mcr-18-0106 |
0.361 |
|
| 2018 |
Rudolph M, Sizemore ST, Lu Y, Teng KY, Basree MM, Reinbolt R, Timmers CD, Leone G, Ostrowski MC, Majumder S, Ramaswamy B. A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer. Breast Cancer Research and Treatment. PMID 29464534 DOI: 10.1007/S10549-018-4718-X |
0.34 |
|
| 2018 |
Hawley CA, Rojo R, Raper A, Sauter KA, Lisowski ZM, Grabert K, Bain CC, Davis GM, Louwe PA, Ostrowski MC, Hume DA, Pridans C, Jenkins SJ.
-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System. Journal of Immunology (Baltimore, Md. : 1950). PMID 29440354 DOI: 10.4049/Jimmunol.1701488 |
0.381 |
|
| 2018 |
Hu E, Waibl-Polania J, Frissora F, Beaver LS, Zapolnik K, Mundy-Bosse BL, Mishra A, Freud AG, Yu J, Byrd JC, Oakes CC, Ostrowski M, Muthusamy N. The ETS1 Transcription Factor Is Implicated in Human and Murine Intermediate NK Cell Development Stages Blood. 132: 2567-2567. DOI: 10.1182/Blood-2018-99-115261 |
0.377 |
|
| 2018 |
McCarter A, Yan R, Serna Alarcon A, Chang C, Kim E, Sha C, Liu Y, Wang Q, Peterson LF, Kuick R, Ryan R, Talpaz M, Samuelson L, Ostrowski M, Chiang MY. Ets1 Enhances Context-Dependent Notch1 Activity in T-Cell Leukemia Blood. 132: 2595-2595. DOI: 10.1182/Blood-2018-99-111376 |
0.418 |
|
| 2018 |
Thies KA, Hammer AM, Hildreth BE, Russell LO, Sizemore ST, Trimboli AJ, Kladney RD, Bolyard CM, Pilarski R, Schoenfield L, Otero J, Chakravarti A, Ringel M, Kaur B, Leone G, ... Ostrowski MC, et al. Abstract 49: Stromal platelet derived growth factor receptor (PDGFRβ) signaling: A novel therapeutic target for breast cancer brain metastasis (BCBM) Tumor Biology. DOI: 10.1158/1538-7445.Am2018-49 |
0.309 |
|
| 2017 |
Pourebrahim R, Zhang Y, Liu B, Gao R, Xiong S, Lin PP, McArthur MJ, Ostrowski MC, Lozano G. Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein. Genes & Development. PMID 29021240 DOI: 10.1101/Gad.304972.117 |
0.366 |
|
| 2017 |
Wu J, Liu X, Nayak SG, Pitarresi JR, Cuitiño MC, Yu L, Hildreth BE, Thies KA, Schilling DJ, Fernandez SA, Leone G, Ostrowski MC. Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele. Plos One. 12: e0184984. PMID 28934293 DOI: 10.1371/Journal.Pone.0184984 |
0.414 |
|
| 2017 |
Liu H, Dowdle JA, Khurshid S, Sullivan NJ, Bertos N, Rambani K, Mair M, Daniel P, Wheeler E, Tang X, Toth K, Lause M, Harrigan ME, Eiring K, Sullivan C, ... ... Ostrowski MC, et al. Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation. Developmental Cell. 41: 392-407.e6. PMID 28535374 DOI: 10.1016/J.Devcel.2017.04.024 |
0.415 |
|
| 2017 |
Hammer AM, Sizemore GM, Shukla VC, Avendano A, Sizemore ST, Chang JJ, Kladney RD, Cuitiño MC, Thies KA, Verfurth Q, Chakravarti A, Yee LD, Leone G, Song JW, Ghadiali SN, ... Ostrowski MC, et al. Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth. Neoplasia (New York, N.Y.). 19: 496-508. PMID 28501760 DOI: 10.1016/J.Neo.2017.04.004 |
0.386 |
|
| 2017 |
Komar HM, Serpa G, Kerscher C, Schwoegl E, Mace TA, Jin M, Yang MC, Chen CS, Bloomston M, Ostrowski MC, Hart PA, Conwell DL, Lesinski GB. Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo. Scientific Reports. 7: 1787. PMID 28496202 DOI: 10.1038/S41598-017-01973-0 |
0.365 |
|
| 2017 |
Sizemore GM, Pitarresi JR, Balakrishnan S, Ostrowski MC. The ETS family of oncogenic transcription factors in solid tumours. Nature Reviews. Cancer. PMID 28450705 DOI: 10.1038/Nrc.2017.20 |
0.405 |
|
| 2016 |
Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. PMID 27797378 DOI: 10.1038/Onc.2016.383 |
0.45 |
|
| 2016 |
Pitarresi JR, Liu X, Sharma SM, Cuitiño MC, Kladney RD, Mace TA, Donohue S, Nayak SG, Qu C, Lee J, Woelke SA, Trela S, LaPak K, Yu L, McElroy J, ... ... Ostrowski MC, et al. Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia (New York, N.Y.). 18: 541-52. PMID 27659014 DOI: 10.1016/J.Neo.2016.07.006 |
0.437 |
|
| 2016 |
Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, ... ... Ostrowski MC, et al. Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. Genes & Development. PMID 27633013 DOI: 10.1101/Gad.283499.116 |
0.438 |
|
| 2016 |
Chaffee BR, Hoang TV, Leonard MR, Bruney DG, Wagner BD, Dowd JR, Leone G, Ostrowski MC, Robinson ML. FGFR and PTEN signaling interact during lens development to regulate cell survival. Developmental Biology. PMID 26764128 DOI: 10.1016/J.Ydbio.2015.12.027 |
0.426 |
|
| 2016 |
Sizemore ST, Mohammad R, Sizemore GM, Yu H, Ostrowski MC, Chakravarti A, Xia F. Relationship of ionizing radiation-induced synthetic lethality of PARP inhibition in BRCA1-proficient cancer cells with p53. Journal of Clinical Oncology. 34: e14115-e14115. DOI: 10.1200/Jco.2016.34.15_Suppl.E14115 |
0.328 |
|
| 2016 |
Thies K, Taffany DA, Mathsyaraja H, Sharma SM, Meisen WH, Liu T, Timmers C, Otero J, Kaur B, Ostrowski MC. Abstract C30: The CSF1-PU.1 pathway in tumor associated macrophages promotes breast cancer growth and progression Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-C30 |
0.441 |
|
| 2016 |
Sizemore G, Mathur A, Thies K, Bolyard C, Sizemore S, Kladney R, Trimboli A, Kaur B, Leone G, Ostrowski M. Abstract C28: Platelet-derived growth factor receptor-β (PDGFRβ) in the breast metastatic tumor microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-C28 |
0.395 |
|
| 2015 |
Mace TA, Shakya R, Elnaggar O, Wilson K, Komar HM, Yang J, Pitarresi JR, Young GS, Ostrowski MC, Ludwig T, Bekaii-Saab T, Bloomston M, Lesinski GB. Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer. Oncotarget. PMID 26575024 DOI: 10.18632/Oncotarget.6332 |
0.392 |
|
| 2015 |
Trikha P, Sharma N, Pena C, Reyes A, Pécot T, Khurshid S, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Ostrowski MC, Leone G. E2f3 in tumor macrophages promotes lung metastasis. Oncogene. PMID 26549026 DOI: 10.1038/Onc.2015.429 |
0.476 |
|
| 2015 |
Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, ... ... Ostrowski MC, et al. Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo. Genes & Development. 29: 1707-20. PMID 26302789 DOI: 10.1101/Gad.262568.115 |
0.341 |
|
| 2015 |
Carey HA, Bronisz A, Cabrera J, Hildreth BE, Cuitiño M, Fu Q, Ahmad A, Toribio RE, Ostrowski MC, Sharma SM. Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-eyed Mutant. Journal of Cellular Physiology. PMID 26218069 DOI: 10.1002/Jcp.25108 |
0.35 |
|
| 2015 |
Nasser MW, Wani NA, Ahirwar DK, Powell CA, Ravi J, Elbaz M, Zhao H, Padilla L, Zhang X, Shilo K, Ostrowski M, Shapiro C, Carson WE, Ganju RK. RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment. Cancer Research. 75: 974-85. PMID 25572331 DOI: 10.1158/0008-5472.Can-14-2161 |
0.385 |
|
| 2015 |
Meisen WH, Dubin S, Sizemore ST, Mathsyaraja H, Thies K, Lehman NL, Boyer P, Jaime-Ramirez AC, Elder JB, Powell K, Chakravarti A, Ostrowski MC, Kaur B. Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies. Molecular Cancer Therapeutics. 14: 307-14. PMID 25376607 DOI: 10.1158/1535-7163.Mct-14-0659 |
0.334 |
|
| 2015 |
Mace T, Shakya R, Pitarresi J, Loftus S, Swanson B, Young G, Zhong X, Zimmers T, Ostrowski M, Ludwig T, Bloomston M, Bekaii-Saab T, Lesinski G. Anti-IL-6 and PD-L1 antibody combination therapy reduces tumor progression in murine models of pancreatic cancer Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P366 |
0.305 |
|
| 2015 |
Pitarresi JR, Ostrowski MC. Abstract A40: Genetic ablation of Smoothened in tumor-associated fibroblasts promotes pancreatic tumorigenesis Cancer Research. 76: 2883-2883. DOI: 10.1158/1538-7445.Tme16-A40 |
0.4 |
|
| 2015 |
Meisen WH, Dubin S, Sizemore S, Mathsyaraja H, Thies K, Lehman N, Boyer P, Jaime-Ramirez AC, Elder JB, Powell K, Ostrowski M, Kaur B. Abstract P6-16-02: Oncolytic viral therapy enhances the survival of mice in a novel model of breast cancer brain metastases Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-16-02 |
0.312 |
|
| 2015 |
Reinbolt RE, Tolliver K, Abdel-Rasoul M, Timmers C, Ramaswamy B, Layman RM, Wesolowski R, Lustberg MB, Mrozek E, Ottman S, Chen J, Shapiro C, Ostrowski MC, Leone GW, Macrae E. Abstract P2-03-03: Incidence of actionable genomic alterations in metastatic breast cancer: A prospective study Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P2-03-03 |
0.307 |
|
| 2015 |
Mathur A, Sizemore GM, Balakrishnan S, Shukla VC, Cuitino M, Trimboli AJ, Ghadiali S, Leone GW, Ostrowski MC. Abstract 985: Stromal PDGFR-α activation stalls mammary ductal development and increases tumorigenic potential of mammary epithelia Cancer Research. 75: 985-985. DOI: 10.1158/1538-7445.Am2015-985 |
0.425 |
|
| 2014 |
Kabbout M, Dakhlallah D, Sharma S, Bronisz A, Srinivasan R, Piper M, Marsh CB, Ostrowski MC. MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation. Plos One. 9: e100693. PMID 24968297 DOI: 10.1371/Journal.Pone.0100693 |
0.381 |
|
| 2014 |
Wallace JA, Pitarresi JR, Sharma N, Palettas M, Cuitiño MC, Sizemore ST, Yu L, Sanderlin A, Rosol TJ, Mehta KD, Sizemore GM, Ostrowski MC. Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis. Frontiers in Oncology. 4: 87. PMID 24795864 DOI: 10.3389/Fonc.2014.00087 |
0.401 |
|
| 2014 |
Bronisz A, Carey HA, Godlewski J, Sif S, Ostrowski MC, Sharma SM. The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF) Journal of Biological Chemistry. 289: 326-334. PMID 24257758 DOI: 10.1074/Jbc.M113.493874 |
0.517 |
|
| 2013 |
Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, ... ... Ostrowski MC, et al. Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. Plos One. 8: e71533. PMID 23977064 DOI: 10.1371/Journal.Pone.0071533 |
0.425 |
|
| 2013 |
Wolford CC, McConoughey SJ, Jalgaonkar SP, Leon M, Merchant AS, Dominick JL, Yin X, Chang Y, Zmuda EJ, O'Toole SA, Millar EK, Roller SL, Shapiro CL, Ostrowski MC, Sutherland RL, et al. Transcription factor ATF3 links host adaptive response to breast cancer metastasis. The Journal of Clinical Investigation. 123: 2893-906. PMID 23921126 DOI: 10.1172/Jci64410 |
0.432 |
|
| 2013 |
Peruzzi P, Bronisz A, Nowicki MO, Wang Y, Ogawa D, Price R, Nakano I, Kwon CH, Hayes J, Lawler SE, Ostrowski MC, Chiocca EA, Godlewski J. MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. Neuro-Oncology. 15: 1212-24. PMID 23733246 DOI: 10.1093/Neuonc/Not055 |
0.352 |
|
| 2013 |
Wojton J, Chu Z, Mathsyaraja H, Meisen WH, Denton N, Kwon CH, Chow LM, Palascak M, Franco R, Bourdeau T, Thornton S, Ostrowski MC, Kaur B, Qi X. Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1517-25. PMID 23732993 DOI: 10.1038/Mt.2013.114 |
0.355 |
|
| 2013 |
Mace TA, Pitaressi J, Shakya R, Frankel W, Eubank T, Bekaii-Saab T, Bloomston M, Phelps M, Ludwig T, Ostrowski M, Lesinski GB. Genetically engineered murine pancreatic cancer models approximate immunophenotypic properties of human patients Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P163 |
0.379 |
|
| 2013 |
Mathsyaraja H, Thies K, Taffany DA, Ostrowski MC. Abstract A27: Micromanaging the microenvironment: The role of microRNA in metastatic mammary tumor-associated macrophages Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A27 |
0.441 |
|
| 2013 |
Balakrishnan S, Wallace JA, Li F, Martin CK, Pecot T, Leone G, Ostrowski MC. Abstract 1633: Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. Cancer Research. 73: 1633-1633. DOI: 10.1158/1538-7445.Am2013-1633 |
0.435 |
|
| 2012 |
Mathsyaraja H, Ostrowski MC. Setting Snail2's pace during EMT Nature Cell Biology. 14: 1122-1123. PMID 23131919 DOI: 10.1038/Ncb2616 |
0.404 |
|
| 2012 |
Kim JW, Evans C, Weidemann A, Takeda N, Lee YS, Stockmann C, Branco-Price C, Brandberg F, Leone G, Ostrowski MC, Johnson RS. Loss of fibroblast HIF-1α accelerates tumorigenesis. Cancer Research. 72: 3187-95. PMID 22556263 DOI: 10.1158/0008-5472.Can-12-0534 |
0.359 |
|
| 2012 |
Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, Srinivasan R, Trimboli AJ, Martin CK, Li F, Yu L, Fernandez SA, Pécot T, Rosol TJ, Cory S, ... ... Ostrowski MC, et al. Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nature Cell Biology. 14: 159-67. PMID 22179046 DOI: 10.1038/Ncb2396 |
0.356 |
|
| 2012 |
Fisher IB, Ostrowski M, Muthusamy N. Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survival. The Journal of Biological Chemistry. 287: 5199-210. PMID 22128184 DOI: 10.1074/Jbc.M111.242602 |
0.368 |
|
| 2012 |
Yee LD, Rolsten S, Rengel R, Wallace JA, Mohler R, Mariano A, Clinton SK, Ostrowski MC. Abstract 5426: Effects of dietary fatty acids on mammary macrophages in HER-2/neu-mediated mammary carcinogenesis Cancer Research. 72: 5426-5426. DOI: 10.1158/1538-7445.Am2012-5426 |
0.323 |
|
| 2011 |
Connelly L, Barham W, Onishko HM, Chen L, Sherrill TP, Zabuawala T, Ostrowski MC, Blackwell TS, Yull FE. NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model. Breast Cancer Research : Bcr. 13: R83. PMID 21884585 DOI: 10.1186/Bcr2935 |
0.791 |
|
| 2011 |
Blackwell TS, Hipps AN, Yamamoto Y, Han W, Barham WJ, Ostrowski MC, Yull FE, Prince LS. NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis. Journal of Immunology (Baltimore, Md. : 1950). 187: 2740-7. PMID 21775686 DOI: 10.4049/Jimmunol.1101495 |
0.33 |
|
| 2011 |
Baran CP, Fischer SN, Nuovo GJ, Kabbout MN, Hitchcock CL, Bringardner BD, McMaken S, Newland CA, Cantemir-Stone CZ, Phillips GS, Ostrowski MC, Marsh CB. Transcription factor ets-2 plays an important role in the pathogenesis of pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 45: 999-1006. PMID 21562315 DOI: 10.1165/Rcmb.2010-0490Oc |
0.339 |
|
| 2011 |
Wallace JA, Li F, Leone G, Ostrowski MC. Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution. Cancer Research. 71: 1203-7. PMID 21303970 DOI: 10.1158/0008-5472.Can-10-3263 |
0.332 |
|
| 2011 |
Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G. E2f1-3 are critical for myeloid development. The Journal of Biological Chemistry. 286: 4783-95. PMID 21115501 DOI: 10.1074/Jbc.M110.182733 |
0.47 |
|
| 2011 |
Bronisz AM, Godlewski J, Wallace J, Merchant A, Leone G, Ostrowski MC. Abstract 512: Reprogramming of the tumor microenvironment by stromalPten-regulated miR-320 Cancer Research. 71: 512-512. DOI: 10.1158/1538-7445.Am2011-512 |
0.358 |
|
| 2011 |
Wolford CC, McConoughey S, Yin X, Merchant A, Leon ME, O'Toole S, Sutherland R, Ostrowski M, Hai T. Abstract 2843: Tumor macrophages utilize ATF3 to promote breast cancer metastasis Cancer Research. 71: 2843-2843. DOI: 10.1158/1538-7445.Am2011-2843 |
0.445 |
|
| 2011 |
Barham W, Connelly L, Onishko HM, Chen L, Sherrill T, Zabuawala T, Ostrowski M, Blackwell T, Yull F. Abstract 2841: Inducible modulation of NF-kappaB in macrophages reveals that timing of intervention may be critical to therapeutic outcome during mammary tumorigenesis Cancer Research. 71: 2841-2841. DOI: 10.1158/1538-7445.Am2011-2841 |
0.794 |
|
| 2010 |
Acharyya S, Sharma SM, Cheng AS, Ladner KJ, He W, Kline W, Wang H, Ostrowski MC, Huang TH, Guttridge DC. TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy. Plos One. 5: e12479. PMID 20814569 DOI: 10.1371/Journal.Pone.0012479 |
0.333 |
|
| 2010 |
Ostrowski MC. A new role for OPG: putting RANKL in its place. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1905-6. PMID 20684024 DOI: 10.1002/Jbmr.206 |
0.402 |
|
| 2010 |
Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, ... ... Ostrowski MC, et al. Allele-specific tumor spectrum in pten knockin mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 5142-7. PMID 20194734 DOI: 10.1073/Pnas.0912524107 |
0.333 |
|
| 2010 |
Zabuawala T, Taffany DA, Sharma SM, Merchant A, Adair B, Srinivasan R, Rosol TJ, Fernandez S, Huang K, Leone G, Ostrowski MC. An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. Cancer Research. 70: 1323-33. PMID 20145133 DOI: 10.1158/0008-5472.Can-09-1474 |
0.805 |
|
| 2010 |
Kim Y, Wallace J, Li F, Ostrowski M, Friedman A. Transformed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: a mathematical model and experiments. Journal of Mathematical Biology. 61: 401-21. PMID 19902212 DOI: 10.1007/S00285-009-0307-2 |
0.38 |
|
| 2010 |
Li F, Wallace JA, Ostrowski MC. ETS Transcription Factors in the Tumor Microenvironment The Open Cancer Journal. 3: 49-54. DOI: 10.2174/1874079001003010049 |
0.467 |
|
| 2010 |
Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen H, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Perle KL, Stromberg P, Rosol TJ, Eng C, ... Ostrowski MC, et al. Abstract 3260: Allele-specific tumor spectrum inPtenknockin mice Cancer Research. 70: 3260-3260. DOI: 10.1158/1538-7445.Am10-3260 |
0.332 |
|
| 2010 |
Connelly L, Barham W, Onishko HM, Zabuawala T, Ostrowski MC, Blackwell TS, Yull FE. Abstract 1352: Macrophage specific regulation reveals both pro- and anti-tumor effects of NF-kappaB during mammary tumor progression Cancer Research. 70: 1352-1352. DOI: 10.1158/1538-7445.Am10-1352 |
0.805 |
|
| 2010 |
Merchant AS, Wallace JA, Trimboli AJ, Gulati P, Loene G, Ostrowski MC. Abstract 110: A bioinformatics view of networking in the mouse mammary microenvironment Cancer Research. 70: 110-110. DOI: 10.1158/1538-7445.Am10-110 |
0.468 |
|
| 2009 |
Srinivasan R, Zabuawala T, Huang H, Zhang J, Gulati P, Fernandez S, Karlo JC, Landreth GE, Leone G, Ostrowski MC. Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis. Plos One. 4: e8283. PMID 20011539 DOI: 10.1371/Journal.Pone.0008283 |
0.78 |
|
| 2009 |
Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, ... ... Ostrowski MC, et al. Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature. 461: 1084-91. PMID 19847259 DOI: 10.1038/Nature08486 |
0.555 |
|
| 2009 |
Pan F, Yu H, Dang EV, Barbi J, Pan X, Grosso JF, Jinasena D, Sharma SM, McCadden EM, Getnet D, Drake CG, Liu JO, Ostrowski MC, Pardoll DM. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (New York, N.Y.). 325: 1142-6. PMID 19696312 DOI: 10.1126/Science.1176077 |
0.387 |
|
| 2009 |
Kampfrath T, Deiuliis JA, Moffatt-Bruce SD, Anderson J, Sun Q, Wood K, Ostrowski MC, Rajagopalan S. A mouse model of yellow fluorescent protein (YFP) expression in hematopoietic cells to assess leukocyte-endothelial interactions in the microcirculation. Microvascular Research. 78: 294-300. PMID 19682464 DOI: 10.1016/J.Mvr.2009.08.001 |
0.359 |
|
| 2009 |
Wei G, Srinivasan R, Cantemir-Stone CZ, Sharma SM, Santhanam R, Weinstein M, Muthusamy N, Man AK, Oshima RG, Leone G, Ostrowski MC. Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 114: 1123-30. PMID 19411629 DOI: 10.1182/Blood-2009-03-211391 |
0.547 |
|
| 2009 |
Sharma SM, Sif S, Ostrowski MC, Sankar U. Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice. Journal of Cellular Physiology. 220: 230-7. PMID 19288495 DOI: 10.1002/Jcp.21755 |
0.75 |
|
| 2009 |
Joshi T, Ganesan LP, Cheney C, Ostrowski MC, Muthusamy N, Byrd JC, Tridandapani S. The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma. Plos One. 4: e4208. PMID 19148288 DOI: 10.1371/Journal.Pone.0004208 |
0.416 |
|
| 2009 |
Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, et al. Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. Circulation Research. 104: 455-65. PMID 19122179 DOI: 10.1161/Circresaha.108.182568 |
0.381 |
|
| 2008 |
Lin HJ, Zuo T, Lin CH, Kuo CT, Liyanarachchi S, Sun S, Shen R, Deatherage DE, Potter D, Asamoto L, Lin S, Yan PS, Cheng AL, Ostrowski MC, Huang TH. Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Research. 68: 10257-66. PMID 19074894 DOI: 10.1158/0008-5472.Can-08-0288 |
0.445 |
|
| 2008 |
Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. The Journal of Clinical Investigation. 118: 3775-89. PMID 18846253 DOI: 10.1172/Jci35711 |
0.404 |
|
| 2008 |
Hou Y, Li F, Karin M, Ostrowski MC. Analysis of the IKKbeta/NF-kappaB signaling pathway during embryonic angiogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2926-35. PMID 18816823 DOI: 10.1002/Dvdy.21723 |
0.37 |
|
| 2008 |
Hume DA, Sasmono T, Himes SR, Sharma SM, Bronisz A, Constantin M, Ostrowski MC, Ross IL. The ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene Journal of Immunology. 180: 6733-6742. PMID 18453593 DOI: 10.4049/Jimmunol.180.10.6733 |
0.45 |
|
| 2008 |
Crotti TN, Sharma SM, Fleming JD, Flannery MR, Ostrowski MC, Goldring SR, McHugh KP. PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter. Journal of Cellular Physiology. 215: 636-44. PMID 18288635 DOI: 10.1002/Jcp.21344 |
0.415 |
|
| 2008 |
Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Research. 68: 937-45. PMID 18245497 DOI: 10.1158/0008-5472.Can-07-2148 |
0.507 |
|
| 2008 |
Sussan TE, Yang A, Li F, Ostrowski MC, Reeves RH. Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome. Nature. 451: 73-5. PMID 18172498 DOI: 10.1038/Nature06446 |
0.344 |
|
| 2007 |
Opavsky R, Wang SH, Trikha P, Raval A, Huang Y, Wu YZ, Rodriguez B, Keller B, Liyanarachchi S, Wei G, Davuluri RV, Weinstein M, Felsher D, Ostrowski M, Leone G, et al. CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. Plos Genetics. 3: 1757-69. PMID 17907813 DOI: 10.1371/Journal.Pgen.0030167 |
0.528 |
|
| 2007 |
Casimiro M, Rodriguez O, Pootrakul L, Aventian M, Lushina N, Cromelin C, Ferzli G, Johnson K, Fricke S, Diba F, Kallakury B, Ohanyerenwa C, Chen M, Ostrowski M, Hung MC, et al. ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo. Cancer Research. 67: 4364-72. PMID 17483350 DOI: 10.1158/0008-5472.Can-06-1898 |
0.369 |
|
| 2007 |
Hu R, Sharma SM, Bronisz A, Srinivasan R, Sankar U, Ostrowski MC. Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors. Molecular and Cellular Biology. 27: 4018-27. PMID 17403896 DOI: 10.1128/Mcb.01839-06 |
0.765 |
|
| 2007 |
Sharma SM, Bronisz A, Hu R, Patel K, Mansky KC, Sif S, Ostrowski MC. MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. The Journal of Biological Chemistry. 282: 15921-9. PMID 17403683 DOI: 10.1074/Jbc.M609723200 |
0.502 |
|
| 2007 |
Meadows NA, Sharma SM, Faulkner GJ, Ostrowski MC, Hume DA, Cassady AI. The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor Journal of Biological Chemistry. 282: 1891-1904. PMID 17105730 DOI: 10.1074/Jbc.M608572200 |
0.5 |
|
| 2007 |
Joshi T, Ganesan LP, Cheney C, Muthusamy N, Byrd JC, Ostrowski MC, Tridandapani S. A critical role for Akt in macrophage cytotoxicity to antibody‐coated tumor cells The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A184-A |
0.383 |
|
| 2006 |
Sharma SM, Hu R, Bronisz A, Meadows N, Lusby T, Fletcher B, Hume DA, Cassady AI, Ostrowski MC. Genetics and genomics of osteoclast differentiation: integrating cell signaling pathways and gene networks. Critical Reviews in Eukaryotic Gene Expression. 16: 253-77. PMID 17073554 DOI: 10.1615/Critreveukargeneexpr.V16.I3.40 |
0.403 |
|
| 2006 |
Anghelina M, Moldovan L, Zabuawala T, Ostrowski MC, Moldovan NI. A subpopulation of peritoneal macrophages form capillarylike lumens and branching patterns in vitro. Journal of Cellular and Molecular Medicine. 10: 708-15. PMID 16989730 DOI: 10.1111/J.1582-4934.2006.Tb00430.X |
0.771 |
|
| 2006 |
Dai B, Kim O, Xie Y, Guo Z, Xu K, Wang B, Kong X, Melamed J, Chen H, Bieberich CJ, Borowsky AD, Kung HJ, Wei G, Ostrowski MC, Brodie A, et al. Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse. Cancer Research. 66: 8058-64. PMID 16912182 DOI: 10.1158/0008-5472.Can-06-1364 |
0.497 |
|
| 2006 |
Chung JH, Ostrowski MC, Romigh T, Minaguchi T, Waite KA, Eng C. The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation. Human Molecular Genetics. 15: 2553-9. PMID 16849370 DOI: 10.1093/Hmg/Ddl177 |
0.421 |
|
| 2006 |
Bronisz A, Sharma SM, Hu R, Godlewski J, Tzivion G, Mansky KC, Ostrowski MC. Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors. Molecular Biology of the Cell. 17: 3897-906. PMID 16822840 DOI: 10.1091/Mbc.E06-05-0470 |
0.468 |
|
| 2006 |
Pengal RA, Ganesan LP, Wei G, Fang H, Ostrowski MC, Tridandapani S. Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt. Molecular Immunology. 43: 1557-64. PMID 16263172 DOI: 10.1016/J.Molimm.2005.09.022 |
0.489 |
|
| 2005 |
Svensson S, Jirström K, Rydén L, Roos G, Emdin S, Ostrowski MC, Landberg G. ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis. Oncogene. 24: 4370-9. PMID 15806151 DOI: 10.1038/Sj.Onc.1208626 |
0.335 |
|
| 2005 |
Wang Y, Zeigler MM, Lam GK, Hunter MG, Eubank TD, Tridandapani S, Ostrowski MC, Marsh CB. Akt Activation Regulates Macrophage Survival and Differentiation: Role of M-CSF and Endogenous ROS. Blood. 106: 2208-2208. DOI: 10.1182/Blood.V106.11.2208.2208 |
0.396 |
|
| 2004 |
Ganesan LP, Wei G, Pengal RA, Moldovan L, Moldovan N, Ostrowski MC, Tridandapani S. The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase. The Journal of Biological Chemistry. 279: 54416-25. PMID 15485887 DOI: 10.1074/Jbc.M408188200 |
0.549 |
|
| 2004 |
Wei G, Guo J, Doseff AI, Kusewitt DF, Man AK, Oshima RG, Ostrowski MC. Activated Ets2 is required for persistent inflammatory responses in the motheaten viable model. Journal of Immunology (Baltimore, Md. : 1950). 173: 1374-9. PMID 15240733 DOI: 10.4049/Jimmunol.173.2.1374 |
0.548 |
|
| 2004 |
Sankar U, Patel K, Rosol TJ, Ostrowski MC. RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 1339-48. PMID 15231022 DOI: 10.1359/Jbmr.040321 |
0.705 |
|
| 2004 |
Cao X, Wei G, Fang H, Guo J, Weinstein M, Marsh CB, Ostrowski MC, Tridandapani S. The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages. Journal of Immunology (Baltimore, Md. : 1950). 172: 4851-7. PMID 15067063 DOI: 10.4049/Jimmunol.172.8.4851 |
0.54 |
|
| 2004 |
Meadows NA, Faulkner G, Wells C, Ravasi T, Hume D, Sankar U, Hu R, Ostrowski M, Cassady A. Novel genes regulated by microphthalmia transcription factor in macrophages and osteoclasts Journal of Bone and Mineral Research. 19. DOI: 10.1002/Jbmr.5650191306 |
0.755 |
|
| 2003 |
Cassady AI, Luchin A, Ostrowski MC, Hume DA. Regulation of the Murine TRACP Gene Promoter Journal of Bone and Mineral Research. 18: 1901-1904. PMID 14584903 DOI: 10.1359/Jbmr.2003.18.10.1901 |
0.819 |
|
| 2003 |
Petrovic N, Bhagwat SV, Ratzan WJ, Ostrowski MC, Shapiro LH. CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells. The Journal of Biological Chemistry. 278: 49358-68. PMID 14507917 DOI: 10.1074/Jbc.M308071200 |
0.332 |
|
| 2003 |
Wei G, Schaffner AE, Baker KM, Mansky KC, Ostrowski MC. Ets-2 interacts with co-repressor BS69 to repress target gene expression. Anticancer Research. 23: 2173-8. PMID 12894593 |
0.744 |
|
| 2003 |
So H, Rho J, Jeong D, Park R, Fisher DE, Ostrowski MC, Choi Y, Kim N. Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression. The Journal of Biological Chemistry. 278: 24209-16. PMID 12695521 DOI: 10.1074/Jbc.M302940200 |
0.405 |
|
| 2003 |
Baker KM, Wei G, Schaffner AE, Ostrowski MC. Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. The Journal of Biological Chemistry. 278: 17876-84. PMID 12637547 DOI: 10.1074/Jbc.M209480200 |
0.736 |
|
| 2003 |
Wu L, de Bruin A, Saavedra HI, Starovic M, Trimboli A, Yang Y, Opavska J, Wilson P, Thompson JC, Ostrowski MC, Rosol TJ, Woollett LA, Weinstein M, Cross JC, Robinson ML, et al. Extra-embryonic function of Rb is essential for embryonic development and viability. Nature. 421: 942-7. PMID 12607001 DOI: 10.1038/Nature01417 |
0.356 |
|
| 2003 |
Ghosh D, Ezashi T, Ostrowski MC, Roberts RM. A central role for Ets-2 in the transcriptional regulation and cyclic adenosine 5'-monophosphate responsiveness of the human chorionic gonadotropin-beta subunit gene. Molecular Endocrinology (Baltimore, Md.). 17: 11-26. PMID 12511603 DOI: 10.1210/Me.2002-0223 |
0.448 |
|
| 2003 |
Sasmono RT, Oceandy D, Pollard JW, Tong W, Pavli P, Wainwright BJ, Ostrowski MC, Himes SR, Hume DA. A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood. 101: 1155-63. PMID 12393599 DOI: 10.1182/Blood-2002-02-0569 |
0.468 |
|
| 2002 |
Weng LP, Brown JL, Baker KM, Ostrowski MC, Eng C. PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway. Human Molecular Genetics. 11: 1687-96. PMID 12095911 DOI: 10.1093/Hmg/11.15.1687 |
0.339 |
|
| 2002 |
Mansky KC, Sulzbacher S, Purdom G, Nelsen L, Hume DA, Rehli M, Ostrowski MC. The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter Journal of Leukocyte Biology. 71: 304-310. PMID 11818452 DOI: 10.1189/Jlb.71.2.304 |
0.787 |
|
| 2002 |
Mansky KC, Marfatia K, Purdom GH, Luchin A, Hume DA, Ostrowski MC. The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts Journal of Leukocyte Biology. 71: 295-303. PMID 11818451 DOI: 10.1189/Jlb.71.2.295 |
0.477 |
|
| 2002 |
Mansky KC, Sankar U, Han J, Ostrowski MC. Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling. The Journal of Biological Chemistry. 277: 11077-83. PMID 11792706 DOI: 10.1074/Jbc.M111696200 |
0.747 |
|
| 2001 |
Luchin A, Suchting S, Merson T, Rosol TJ, Hume DA, Cassady AI, Ostrowski MC. Genetic and Physical Interactions between Microphthalmia Transcription Factor and PU.1 Are Necessary for Osteoclast Gene Expression and Differentiation Journal of Biological Chemistry. 276: 36703-36710. PMID 11481336 DOI: 10.1074/Jbc.M106418200 |
0.816 |
|
| 2000 |
Smith JL, Schaffner AE, Hofmeister JK, Hartman M, Wei G, Forsthoefel D, Hume DA, Ostrowski MC. ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice. Molecular and Cellular Biology. 20: 8026-34. PMID 11027273 DOI: 10.1128/Mcb.20.21.8026-8034.2000 |
0.747 |
|
| 2000 |
Luchin A, Purdom G, Murphy K, Clark MY, Angel N, Cassady AI, Hume DA, Ostrowski MC. The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 451-60. PMID 10750559 DOI: 10.1359/Jbmr.2000.15.3.451 |
0.746 |
|
| 2000 |
Angel NZ, Walsh N, Forwood MR, Ostrowski MC, Cassady AI, Hume DA. Transgenic mice overexpressing tartrate-resistant acid phosphatase exhibit an increased rate of bone turnover Journal of Bone and Mineral Research. 15: 103-110. PMID 10646119 DOI: 10.1359/Jbmr.2000.15.1.103 |
0.373 |
|
| 1999 |
Kelley TW, Graham MM, Doseff AI, Pomerantz RW, Lau SM, Ostrowski MC, Franke TF, Marsh CB. Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B. The Journal of Biological Chemistry. 274: 26393-8. PMID 10473597 DOI: 10.1074/Jbc.274.37.26393 |
0.356 |
|
| 1999 |
Rehli M, Den Elzen N, Cassady AI, Ostrowski MC, Hume DA. Cloning and characterization of the murine genes for bHlH-ZIP transcription factors TFEC and TFEB reveal a common gene organization for all MiT subfamily members Genomics. 56: 111-120. PMID 10036191 DOI: 10.1006/Geno.1998.5588 |
0.411 |
|
| 1999 |
Lichanska AM, Browne CM, Henkel GW, Murphy KM, Ostrowski MC, McKercher SR, Maki RA, Hume DA. Differentiation of the Mononuclear Phagocyte System During Mouse Embryogenesis: The Role of Transcription Factor PU.1 Blood. 94: 127-138. DOI: 10.1182/Blood.V94.1.127.413K07_127_138 |
0.447 |
|
| 1998 |
Fowles LF, Martin ML, Nelsen L, Stacey KJ, Redd D, Clark YM, Nagamine Y, McMahon M, Hume DA, Ostrowski MC. Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signaling Molecular and Cellular Biology. 18: 5148-5156. PMID 9710599 DOI: 10.1128/Mcb.18.9.5148 |
0.388 |
|
| 1998 |
Ezashi T, Ealy AD, Ostrowski MC, Roberts RM. Control of interferon-tau gene expression by Ets-2. Proceedings of the National Academy of Sciences of the United States of America. 95: 7882-7. PMID 9653109 DOI: 10.1073/PNAS.95.14.7882 |
0.329 |
|
| 1998 |
Ross IL, Yue X, Ostrowski MC, Hume DA. Interaction between PU.1 and another Ets family transcription factor promotes macrophage-specific basal transcription initiation Journal of Biological Chemistry. 273: 6662-6669. PMID 9506963 DOI: 10.1074/Jbc.273.12.6662 |
0.455 |
|
| 1997 |
McCarthy SA, Chen D, Yang BS, Garcia Ramirez JJ, Cherwinski H, Chen XR, Klagsbrun M, Hauser CA, Ostrowski MC, McMahon M. Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1. Molecular and Cellular Biology. 17: 2401-12. PMID 9111309 DOI: 10.1128/Mcb.17.5.2401 |
0.434 |
|
| 1997 |
Hume DA, Yue X, Ross IL, Favot P, Lichanska A, Ostrowski MC. Regulation of CSF-1 receptor expression Molecular Reproduction and Development. 46: 46-53. PMID 8981363 DOI: 10.1002/(Sici)1098-2795(199701)46:1<46::Aid-Mrd8>3.0.Co;2-R |
0.463 |
|
| 1996 |
Yue X, Ross IL, Browne CM, Lichanska A, Favot P, Ostrowski MC, Hume DA. Transcriptional control of the expression of the c-fms gene encoding the receptor for macrophage colony-stimulating factor (CSF-1). Immunobiology. 195: 461-76. PMID 8933151 DOI: 10.1016/S0171-2985(96)80016-7 |
0.419 |
|
| 1996 |
Bradford AP, Conrad KE, Tran PH, Ostrowski MC, Gutierrez-Hartmann A. GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element. The Journal of Biological Chemistry. 271: 24639-48. PMID 8798730 DOI: 10.1074/Jbc.271.40.24639 |
0.374 |
|
| 1996 |
Colman MS, Ostrowski MC. The transactivation potential of a c-Myc N-terminal region (residues 92-143) is regulated by growth factor/Ras signaling. Nucleic Acids Research. 24: 1971-8. PMID 8657582 DOI: 10.1093/Nar/24.10.1971 |
0.358 |
|
| 1996 |
Yang BS, Hauser CA, Henkel G, Colman MS, Van Beveren C, Stacey KJ, Hume DA, Maki RA, Ostrowski MC. Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2. Molecular and Cellular Biology. 16: 538-47. PMID 8552081 DOI: 10.1128/Mcb.16.2.538 |
0.381 |
|
| 1995 |
Jin DI, Jameson SB, Reddy MA, Schenkman D, Ostrowski MC. Alterations in differentiation and behavior of monocytic phagocytes in transgenic mice that express dominant suppressors of ras signaling. Molecular and Cellular Biology. 15: 693-703. PMID 7823938 DOI: 10.1128/Mcb.15.2.693 |
0.459 |
|
| 1995 |
Stacey KJ, Fowles LF, Colman MS, Ostrowski MC, Hume DA. Regulation of urokinase-type plasminogen activator gene transcription by macrophage colony-stimulating factor Molecular and Cellular Biology. 15: 3430-3441. PMID 7760840 DOI: 10.1128/Mcb.15.6.3430 |
0.481 |
|
| 1995 |
Altschuler DL, Peterson SN, Ostrowski MC, Lapetina EG. Cyclic AMP-dependent activation of Rap1b. The Journal of Biological Chemistry. 270: 10373-6. PMID 7737967 DOI: 10.1074/Jbc.270.18.10373 |
0.333 |
|
| 1994 |
Reddy MA, Yang BS, Yue X, Barnett CJ, Ross IL, Sweet MJ, Hume DA, Ostrowski MC. Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. The Journal of Experimental Medicine. 180: 2309-19. PMID 7964503 DOI: 10.1084/Jem.180.6.2309 |
0.386 |
|
| 1992 |
Langer SJ, Bortner DM, Roussel MF, Sherr CJ, Ostrowski MC. Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression Molecular and Cellular Biology. 12: 5355-5362. PMID 1448070 DOI: 10.1128/Mcb.12.12.5355 |
0.415 |
|
| 1992 |
Reddy MA, Langer SJ, Colman MS, Ostrowski MC. An enhancer element responsive to ras and fms signaling pathways is composed of two distinct nuclear factor binding sites. Molecular Endocrinology (Baltimore, Md.). 6: 1051-60. PMID 1324418 DOI: 10.1210/Mend.6.7.1324418 |
0.383 |
|
| 1991 |
Bortner DM, Ostrowski MC. Analysis of the v-myb structural components important for transactivation of gene expression Nucleic Acids Research. 19: 1533-1539. PMID 2027762 DOI: 10.1093/Nar/19.7.1533 |
0.372 |
|
| 1991 |
Bortner DM, Ulivi M, Roussel MF, Ostrowski MC. The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor. Genes & Development. 5: 1777-85. PMID 1717344 DOI: 10.1101/Gad.5.10.1777 |
0.345 |
|
| 1990 |
Owen RD, Bortner DM, Ostrowski MC. ras oncogene activation of a VL30 transcriptional element is linked to transformation. Molecular and Cellular Biology. 10: 1-9. PMID 2403633 DOI: 10.1128/Mcb.10.1.1 |
0.352 |
|
| 1990 |
Owen RD, Ostrowski MC. Transcriptional activation of a conserved sequence element by ras requires a nuclear factor distinct from c-fos or c-jun. Proceedings of the National Academy of Sciences of the United States of America. 87: 3866-70. PMID 2111019 DOI: 10.1073/Pnas.87.10.3866 |
0.345 |
|
| 1989 |
Langer SJ, Ostrowski MC. Negative regulation of transcription in vitro by a glucocorticoid response element is mediated by a trans-acting factor. Molecular and Cellular Biology. 8: 3872-81. PMID 2851730 DOI: 10.1128/Mcb.8.9.3872 |
0.476 |
|
| 1984 |
Hager GL, Richard-Foy H, Kessel M, Wheeler D, Lichtler AC, Ostrowski MC. The mouse mammary tumor virus model in studies of glucocorticoid regulation. Recent Progress in Hormone Research. 40: 121-42. PMID 6091192 DOI: 10.1016/B978-0-12-571140-1.50008-6 |
0.324 |
|
| 1984 |
Ostrowski M, Huang A, Kessel M, Wolford R, Hager G. Modulation of enhancer activity by the hormone responsive regulatory element from mouse mammary tumor virus. The Embo Journal. 3: 1891-1899. DOI: 10.1002/J.1460-2075.1984.Tb02064.X |
0.304 |
|
| 1983 |
Ostrowski MC, Richard-Foy H, Wolford RG, Berard DS, Hager GL. Glucocorticoid regulation of transcription at an amplified, episomal promoter. Molecular and Cellular Biology. 3: 2045-57. PMID 6318079 DOI: 10.1128/Mcb.3.11.2045 |
0.426 |
|
| 1982 |
Huang AL, Ostrowski MC, Berard D, Hager GL. Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus. Cell. 27: 245-55. PMID 6277498 DOI: 10.1016/0092-8674(81)90408-6 |
0.374 |
|
| 1981 |
Ostrowski MC, Berard D, Hager GL. Specific transcriptional initiation in vitro on murine type C retrovirus promoters. Proceedings of the National Academy of Sciences of the United States of America. 78: 4485-9. PMID 6270679 DOI: 10.1073/Pnas.78.7.4485 |
0.336 |
|
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