| Year |
Citation |
Score |
| 2023 |
Chang W, Zhao Y, Rayêe D, Xie Q, Suzuki M, Zheng D, Cvekl A. Dynamic changes in whole genome DNA methylation, chromatin and gene expression during mouse lens differentiation. Epigenetics & Chromatin. 16: 4. PMID 36698218 DOI: 10.1186/s13072-023-00478-7 |
0.373 |
|
| 2022 |
Cvekl A, Camerino MJ. Generation of Lens Progenitor Cells and Lentoid Bodies from Pluripotent Stem Cells: Novel Tools for Human Lens Development and Ocular Disease Etiology. Cells. 11. PMID 36359912 DOI: 10.3390/cells11213516 |
0.318 |
|
| 2022 |
Diacou R, Nandigrami P, Fiser A, Liu W, Ashery-Padan R, Cvekl A. Cell fate decisions, transcription factors and signaling during early retinal development. Progress in Retinal and Eye Research. 101093. PMID 35817658 DOI: 10.1016/j.preteyeres.2022.101093 |
0.314 |
|
| 2021 |
Cvekl A, Eliscovich C. Crystallin gene expression: Insights from studies of transcriptional bursting. Experimental Eye Research. 207: 108564. PMID 33894228 DOI: 10.1016/j.exer.2021.108564 |
0.398 |
|
| 2019 |
Martynova E, Zhao Y, Xie Q, Zheng D, Cvekl A. Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3. Open Biology. 9: 190220. PMID 31847788 DOI: 10.1098/Rsob.190220 |
0.503 |
|
| 2019 |
Bhansali P, Cvekl A, Liu W. A distal enhancer that directs Otx2 expression in the retinal pigment epithelium and neuroretina. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 31658410 DOI: 10.1002/Dvdy.127 |
0.421 |
|
| 2019 |
Ravichandran M, Lei R, Tang Q, Zhao Y, Lee J, Ma L, Chrysanthou S, Lorton BM, Cvekl A, Shechter D, Zheng D, Dawlaty MM. Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells. Cell Reports. 28: 1993-2003.e5. PMID 31433977 DOI: 10.1016/J.Celrep.2019.07.080 |
0.475 |
|
| 2019 |
Kim S, Lowe A, Dharmat R, Lee S, Owen LA, Wang J, Shakoor A, Li Y, Morgan DJ, Hejazi AA, Cvekl A, DeAngelis MM, Zhou ZJ, Chen R, Liu W. Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids. Proceedings of the National Academy of Sciences of the United States of America. PMID 31072937 DOI: 10.1073/Pnas.1901572116 |
0.349 |
|
| 2019 |
Zhao Y, Zheng D, Cvekl A. Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways. Epigenetics & Chromatin. 12: 27. PMID 31053165 DOI: 10.1186/S13072-019-0272-Y |
0.509 |
|
| 2019 |
Limi S, Zhao Y, Guo P, Lopez-Jones M, Zheng D, Singer RH, Skoultchi AI, Cvekl A. Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers. Investigative Ophthalmology & Visual Science. 60: 234-244. PMID 30646012 DOI: 10.1167/Iovs.18-25921 |
0.505 |
|
| 2019 |
Cvekl A. Chromatin dynamics, DNA‐binding transcription factors and lens differentiation Acta Ophthalmologica. 97. DOI: 10.1111/J.1755-3768.2019.8018 |
0.374 |
|
| 2019 |
Cvekl A. Analysis of transcription by ChIP‐seq in the eye: Progress and challenges Acta Ophthalmologica. 97. DOI: 10.1111/J.1755-3768.2019.5002 |
0.399 |
|
| 2018 |
Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W. Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Reports. 25: 2510-2523.e4. PMID 30485816 DOI: 10.1016/J.Celrep.2018.10.106 |
0.422 |
|
| 2018 |
McGreal-Estrada RS, Wolf LV, Cvekl A. Promoter-enhancer looping and shadow enhancers of the mouse αA-crystallin locus. Biology Open. PMID 30404901 DOI: 10.1242/Bio.036897 |
0.454 |
|
| 2018 |
Zhao Y, Wilmarth PA, Cheng C, Limi S, Fowler VM, Zheng D, David LL, Cvekl A. Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers. Experimental Eye Research. PMID 30359574 DOI: 10.1016/J.Exer.2018.10.011 |
0.433 |
|
| 2018 |
Martynova E, Bouchard M, Musil L, Cvekl A. Identification of novel Gata3 distal enhancers active in mouse embryonic lens. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 30295986 DOI: 10.1002/Dvdy.24677 |
0.461 |
|
| 2018 |
Limi S, Senecal A, Coleman RA, Lopez-Jones M, Guo P, Polumbo C, Singer RH, Skoultchi AI, Cvekl A. Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process. The Journal of Biological Chemistry. PMID 29959226 DOI: 10.1074/Jbc.Ra118.001927 |
0.509 |
|
| 2018 |
Zhao Y, Zheng D, Cvekl A. A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Experimental Eye Research. PMID 29883638 DOI: 10.1016/J.Exer.2018.06.004 |
0.503 |
|
| 2018 |
Brennan LA, McGreal-Estrada R, Logan CM, Cvekl A, Menko AS, Kantorow M. BNIP3L/NIX is required for elimination of mitochondria, endoplasmic reticulum and Golgi apparatus during eye lens organelle-free zone formation. Experimental Eye Research. PMID 29879393 DOI: 10.1016/J.Exer.2018.06.003 |
0.456 |
|
| 2017 |
Cvekl A, Zhao Y, McGreal R, Xie Q, Gu X, Zheng D. Evolutionary Origins of Pax6 Control of Crystallin Genes. Genome Biology and Evolution. 9: 2075-2092. PMID 28903537 DOI: 10.1093/Gbe/Evx153 |
0.442 |
|
| 2017 |
Cvekl A, Zhang X. Signaling and Gene Regulatory Networks in Mammalian Lens Development. Trends in Genetics : Tig. PMID 28867048 DOI: 10.1016/J.Tig.2017.08.001 |
0.461 |
|
| 2017 |
Cavalheiro GR, Matos-Rodrigues GE, Zhao Y, Gomes AL, Anand D, Predes D, de Lima S, Abreu JG, Zheng D, Lachke SA, Cvekl A, Martins RAP. N-myc regulates growth and fiber cell differentiation in lens development. Developmental Biology. PMID 28716713 DOI: 10.1016/J.Ydbio.2017.07.002 |
0.476 |
|
| 2017 |
Liu W, Cvekl A. Six3 in a small population of progenitors at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice. Developmental Biology. PMID 28579317 DOI: 10.1016/J.Ydbio.2017.05.026 |
0.375 |
|
| 2017 |
Esteban-Martínez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Mariño G, Seco E, Durand S, Enot D, Graña O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P. Programmed mitophagy is essential for the glycolytic switch during cell differentiation. The Embo Journal. PMID 28465321 DOI: 10.15252/Embj.201695916 |
0.369 |
|
| 2017 |
Cvekl A, Limi S, Zhao Y, McGreal R, Zheng D. Transcriptional dynamics, denucleation, and gene regulation in embryonic lens development Acta Ophthalmologica. 95. DOI: 10.1111/J.1755-3768.2017.01165 |
0.518 |
|
| 2016 |
Sun J, Zhao Y, McGreal R, Cohen-Tayar Y, Rockowitz S, Wilczek C, Ashery-Padan R, Shechter D, Zheng D, Cvekl A. Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers. Epigenetics & Chromatin. 9: 37. PMID 27617035 DOI: 10.1186/S13072-016-0087-Z |
0.38 |
|
| 2016 |
Menuchin-Lasowski Y, Oren-Giladi P, Xie Q, Ezra-Elia R, Ofri R, Peled-Hajaj S, Chen F, Higashi Y, Van de Putte T, Kondoh H, Huylebroeck D, Cvekl A, Ashery-Padan R. Sip1/Zeb2 regulates the generation of the inner nuclear layer retinal cell lineages in mammals. Development (Cambridge, England). PMID 27385012 DOI: 10.1242/Dev.136101 |
0.439 |
|
| 2016 |
He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, ... ... Cvekl A, et al. Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development (Cambridge, England). 143: 1937-47. PMID 27246713 DOI: 10.1242/Dev.135285 |
0.725 |
|
| 2016 |
Lowe A, Harris R, Bhansali P, Cvekl A, Liu W. Intercellular Adhesion-Dependent Cell Survival and ROCK-Regulated Actomyosin-Driven Forces Mediate Self-Formation of a Retinal Organoid. Stem Cell Reports. PMID 27132890 DOI: 10.1016/J.Stemcr.2016.03.011 |
0.331 |
|
| 2016 |
Cvekl A, Callaerts P. PAX6: 25th anniversary and more to learn. Experimental Eye Research. PMID 27126352 DOI: 10.1016/J.Exer.2016.04.017 |
0.466 |
|
| 2016 |
Cvekl A, Limi S, Zhao Y, McGreal R, Xie Q, Zheng D. The α
A-crystallin gene expression in differentiating lens fiber cells, FGF signaling, and transcriptional factories Acta Ophthalmologica. 94. DOI: 10.1111/J.1755-3768.2016.0393 |
0.464 |
|
| 2015 |
Xie Q, McGreal R, Harris R, Gao CY, Liu W, Reneker LW, Musil LS, Cvekl A. Regulation of c-Maf and αA-crystallin in Ocular Lens by FGF Signaling. The Journal of Biological Chemistry. PMID 26719333 DOI: 10.1074/Jbc.M115.705103 |
0.471 |
|
| 2015 |
Lyu L, Whitcomb EA, Jiang S, Chang ML, Gu Y, Duncan MK, Cvekl A, Wang WL, Limi S, Reneker LW, Shang F, Du L, Taylor A. Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation leading to cataract. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26590164 DOI: 10.1096/Fj.15-278036 |
0.337 |
|
| 2015 |
Sun J, Rockowitz S, Chauss D, Wang P, Kantorow M, Zheng D, Cvekl A. Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators. Molecular Vision. 21: 955-73. PMID 26330747 |
0.329 |
|
| 2015 |
Hejtmancik JF, Riazuddin SA, McGreal R, Liu W, Cvekl A, Shiels A. Lens Biology and Biochemistry. Progress in Molecular Biology and Translational Science. 134: 169-201. PMID 26310155 DOI: 10.1016/Bs.Pmbts.2015.04.007 |
0.401 |
|
| 2015 |
Cvekl A, McGreal R, Liu W. Lens Development and Crystallin Gene Expression. Progress in Molecular Biology and Translational Science. 134: 129-67. PMID 26310154 DOI: 10.1016/Bs.Pmbts.2015.05.001 |
0.464 |
|
| 2015 |
Sun J, Rockowitz S, Xie Q, Ashery-Padan R, Zheng D, Cvekl A. Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development. Nucleic Acids Research. 43: 6827-46. PMID 26138486 DOI: 10.1093/Nar/Gkv589 |
0.469 |
|
| 2014 |
Cvekl A, Ashery-Padan R. The cellular and molecular mechanisms of vertebrate lens development. Development (Cambridge, England). 141: 4432-47. PMID 25406393 DOI: 10.1242/Dev.107953 |
0.472 |
|
| 2014 |
Castellanos R, Xie Q, Zheng D, Cvekl A, Morrow BE. Mammalian TBX1 preferentially binds and regulates downstream targets via a tandem T-site repeat. Plos One. 9: e95151. PMID 24797903 DOI: 10.1371/Journal.Pone.0095151 |
0.414 |
|
| 2014 |
Xie Q, Ung D, Khafizov K, Fiser A, Cvekl A. Gene regulation by PAX6: structural-functional correlations of missense mutants and transcriptional control of Trpm3/miR-204. Molecular Vision. 20: 270-82. PMID 24623969 |
0.355 |
|
| 2014 |
Cvekl A, Friedman IB, Semina EV. Lens-specific transcription factors and their roles in diagnosis and treatment of human congenital cataract Lens Epithelium and Posterior Capsular Opacification. 105-130. DOI: 10.1007/978-4-431-54300-8_6 |
0.438 |
|
| 2013 |
Wolf L, Gao CS, Gueta K, Xie Q, Chevallier T, Podduturi NR, Sun J, Conte I, Zelenka PS, Ashery-Padan R, Zavadil J, Cvekl A. Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation. G3 (Bethesda, Md.). 3: 2239-55. PMID 24142921 DOI: 10.1534/G3.113.008698 |
0.343 |
|
| 2013 |
Wolf L, Harrison W, Huang J, Xie Q, Xiao N, Sun J, Kong L, Lachke SA, Kuracha MR, Govindarajan V, Brindle PK, Ashery-Padan R, Beebe DC, Overbeek PA, Cvekl A. Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. Nucleic Acids Research. 41: 10199-214. PMID 24038357 DOI: 10.1093/Nar/Gkt824 |
0.4 |
|
| 2013 |
Shaham O, Gueta K, Mor E, Oren-Giladi P, Grinberg D, Xie Q, Cvekl A, Shomron N, Davis N, Keydar-Prizant M, Raviv S, Pasmanik-Chor M, Bell RE, Levy C, Avellino R, et al. Pax6 regulates gene expression in the vertebrate lens through miR-204. Plos Genetics. 9: e1003357. PMID 23516376 DOI: 10.1371/Journal.Pgen.1003357 |
0.418 |
|
| 2013 |
Walcher T, Xie Q, Sun J, Irmler M, Beckers J, Öztürk T, Niessing D, Stoykova A, Cvekl A, Ninkovic J, Götz M. Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation. Development (Cambridge, England). 140: 1123-36. PMID 23404109 DOI: 10.1242/Dev.082875 |
0.439 |
|
| 2013 |
Xie Q, Yang Y, Huang J, Ninkovic J, Walcher T, Wolf L, Vitenzon A, Zheng D, Götz M, Beebe DC, Zavadil J, Cvekl A. Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. Plos One. 8: e54507. PMID 23342162 DOI: 10.1371/Journal.Pone.0054507 |
0.533 |
|
| 2013 |
Braunger BM, Ohlmann A, Koch M, Tanimoto N, Volz C, Yang Y, Bösl MR, Cvekl A, Jägle H, Seeliger MW, Tamm ER. Constitutive overexpression of Norrin activates Wnt/β-catenin and endothelin-2 signaling to protect photoreceptors from light damage. Neurobiology of Disease. 50: 1-12. PMID 23009755 DOI: 10.1016/J.Nbd.2012.09.008 |
0.316 |
|
| 2012 |
Brennan LA, Kantorow WL, Chauss D, McGreal R, He S, Mattucci L, Wei J, Riazuddin SA, Cvekl A, Hejtmancik JF, Kantorow M. Spatial expression patterns of autophagy genes in the eye lens and induction of autophagy in lens cells. Molecular Vision. 18: 1773-86. PMID 22815631 |
0.677 |
|
| 2012 |
He S, Cvekl A. Focus on molecules: Brg1: a range of functions during eye development. Experimental Eye Research. 103: 117-8. PMID 21963585 DOI: 10.1016/J.Exer.2011.09.007 |
0.64 |
|
| 2011 |
Xie Q, Cvekl A. The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops. The Journal of Biological Chemistry. 286: 43259-71. PMID 21998302 DOI: 10.1074/Jbc.M111.264580 |
0.496 |
|
| 2010 |
He S, Pirity MK, Wang WL, Wolf L, Chauhan BK, Cveklova K, Tamm ER, Ashery-Padan R, Metzger D, Nakai A, Chambon P, Zavadil J, Cvekl A. Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation. Epigenetics & Chromatin. 3: 21. PMID 21118511 DOI: 10.1186/1756-8935-3-21 |
0.73 |
|
| 2010 |
Ninkovic J, Pinto L, Petricca S, Lepier A, Sun J, Rieger MA, Schroeder T, Cvekl A, Favor J, Götz M. The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin αA. Neuron. 68: 682-94. PMID 21092858 DOI: 10.1016/J.Neuron.2010.09.030 |
0.334 |
|
| 2010 |
Caceres A, Shang F, Wawrousek E, Liu Q, Avidan O, Cvekl A, Yang Y, Haririnia A, Storaska A, Fushman D, Kuszak J, Dudek E, Smith D, Taylor A. Perturbing the ubiquitin pathway reveals how mitosis is hijacked to denucleate and regulate cell proliferation and differentiation in vivo. Plos One. 5: e13331. PMID 20975996 DOI: 10.1371/Journal.Pone.0013331 |
0.453 |
|
| 2010 |
Zhou J, Liu Y, Zhang W, Popov VM, Wang M, Pattabiraman N, Suñé C, Cvekl A, Wu K, Jiang J, Wang C, Pestell RG. Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1. The Journal of Biological Chemistry. 285: 40342-50. PMID 20956529 DOI: 10.1074/Jbc.M110.156141 |
0.491 |
|
| 2010 |
Wang WL, Li Q, Xu J, Cvekl A. Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of NCOA6 and result in p53-dependent and p53-independent apoptosis. Molecular Biology of the Cell. 21: 2453-68. PMID 20484573 DOI: 10.1091/Mbc.E09-12-1031 |
0.428 |
|
| 2010 |
Yang C, Yang Y, Brennan L, Bouhassira EE, Kantorow M, Cvekl A. Efficient generation of lens progenitor cells and lentoid bodies from human embryonic stem cells in chemically defined conditions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3274-83. PMID 20410439 DOI: 10.1096/Fj.10-157255 |
0.418 |
|
| 2010 |
Cvekl A, Mitton KP. Epigenetic regulatory mechanisms in vertebrate eye development and disease. Heredity. 105: 135-51. PMID 20179734 DOI: 10.1038/hdy.2010.16 |
0.374 |
|
| 2009 |
Cvekl A, Wang WL. Retinoic acid signaling in mammalian eye development. Experimental Eye Research. 89: 280-91. PMID 19427305 DOI: 10.1016/J.Exer.2009.04.012 |
0.361 |
|
| 2009 |
Wolf LV, Yang Y, Wang J, Xie Q, Braunger B, Tamm ER, Zavadil J, Cvekl A. Identification of pax6-dependent gene regulatory networks in the mouse lens. Plos One. 4: e4159. PMID 19132093 DOI: 10.1371/Journal.Pone.0004159 |
0.52 |
|
| 2009 |
Wolf LV, Yang Y, Wang J, Xie Q, Braunger B, Tamm ER, Zavadil J, Cvekl A. Correction: Identification of Pax6-Dependent Gene Regulatory Networks in the Mouse Lens Plos One. 4. DOI: 10.1371/Annotation/71D78295-Dc0F-4E78-9C99-45B730952D9B |
0.307 |
|
| 2009 |
Cvekl A, Zheng D. Gene sharing and evolution Human Genomics. 4: 66. DOI: 10.1186/1479-7364-4-1-66 |
0.33 |
|
| 2008 |
Oron-Karni V, Farhy C, Elgart M, Marquardt T, Remizova L, Yaron O, Xie Q, Cvekl A, Ashery-Padan R. Dual requirement for Pax6 in retinal progenitor cells. Development (Cambridge, England). 135: 4037-47. PMID 19004853 DOI: 10.1242/Dev.028308 |
0.396 |
|
| 2008 |
Wolf L, Yang Y, Wawrousek E, Cvekl A. Transcriptional regulation of mouse alpha A-crystallin gene in a 148kb Cryaa BAC and its derivates. Bmc Developmental Biology. 8: 88. PMID 18803847 DOI: 10.1186/1471-213X-8-88 |
0.476 |
|
| 2008 |
Chen Y, Doughman YQ, Gu S, Jarrell A, Aota S, Cvekl A, Watanabe M, Dunwoodie SL, Johnson RS, van Heyningen V, Kleinjan DA, Beebe DC, Yang YC. Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis. Development (Cambridge, England). 135: 2939-48. PMID 18653562 DOI: 10.1242/Dev.021097 |
0.442 |
|
| 2008 |
Pontoriero GF, Deschamps P, Ashery-Padan R, Wong R, Yang Y, Zavadil J, Cvekl A, Sullivan S, Williams T, West-Mays JA. Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 602-17. PMID 18224708 DOI: 10.1002/Dvdy.21445 |
0.335 |
|
| 2007 |
Yang Y, Cvekl A. Large Maf Transcription Factors: Cousins of AP-1 Proteins and Important Regulators of Cellular Differentiation. The Einstein Journal of Biology and Medicine : Ejbm. 23: 2-11. PMID 18159220 DOI: 10.23861/Ejbm20072347 |
0.447 |
|
| 2007 |
Cvekl A, Duncan MK. Genetic and epigenetic mechanisms of gene regulation during lens development. Progress in Retinal and Eye Research. 26: 555-97. PMID 17905638 DOI: 10.1016/J.Preteyeres.2007.07.002 |
0.541 |
|
| 2007 |
Pirity MK, Wang WL, Wolf LV, Tamm ER, Schreiber-Agus N, Cvekl A. Rybp, a polycomb complex-associated protein, is required for mouse eye development. Bmc Developmental Biology. 7: 39. PMID 17470285 DOI: 10.1186/1471-213X-7-39 |
0.368 |
|
| 2007 |
Yang Y, Wolf LV, Cvekl A. Distinct embryonic expression and localization of CBP and p300 histone acetyltransferases at the mouse alphaA-crystallin locus in lens. Journal of Molecular Biology. 369: 917-26. PMID 17467007 DOI: 10.1016/J.Jmb.2007.04.004 |
0.504 |
|
| 2007 |
Wu K, Liu M, Li A, Donninger H, Rao M, Jiao X, Lisanti MP, Cvekl A, Birrer M, Pestell RG. Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Molecular Biology of the Cell. 18: 755-67. PMID 17182846 DOI: 10.1091/Mbc.E06-09-0793 |
0.355 |
|
| 2006 |
Wu K, Li A, Rao M, Liu M, Dailey V, Yang Y, Di Vizio D, Wang C, Lisanti MP, Sauter G, Russell RG, Cvekl A, Pestell RG. DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth. Molecular and Cellular Biology. 26: 7116-29. PMID 16980615 DOI: 10.1128/Mcb.00268-06 |
0.358 |
|
| 2006 |
Yang Y, Stopka T, Golestaneh N, Wang Y, Wu K, Li A, Chauhan BK, Gao CY, Cveklová K, Duncan MK, Pestell RG, Chepelinsky AB, Skoultchi AI, Cvekl A. Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin. The Embo Journal. 25: 2107-18. PMID 16675956 DOI: 10.1038/Sj.Emboj.7601114 |
0.503 |
|
| 2005 |
Yang Y, Cvekl A. Tissue-specific regulation of the mouse alphaA-crystallin gene in lens via recruitment of Pax6 and c-Maf to its promoter. Journal of Molecular Biology. 351: 453-69. PMID 16023139 DOI: 10.1016/J.Jmb.2005.05.072 |
0.54 |
|
| 2005 |
Castellini M, Wolf LV, Chauhan BK, Galileo DS, Kilimann MW, Cvekl A, Duncan MK. Palm is expressed in both developing and adult mouse lens and retina. Bmc Ophthalmology. 5: 14. PMID 15969763 DOI: 10.1186/1471-2415-5-14 |
0.401 |
|
| 2005 |
Ohlmann A, Scholz M, Goldwich A, Chauhan BK, Hudl K, Ohlmann AV, Zrenner E, Berger W, Cvekl A, Seeliger MW, Tamm ER. Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1701-10. PMID 15716406 DOI: 10.1523/Jneurosci.4756-04.2005 |
0.355 |
|
| 2004 |
Cvekl A, Yang Y, Chauhan BK, Cveklova K. Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens. The International Journal of Developmental Biology. 48: 829-44. PMID 15558475 DOI: 10.1387/Ijdb.041866Ac |
0.543 |
|
| 2004 |
Yang Y, Chauhan BK, Cveklova K, Cvekl A. Transcriptional regulation of mouse alphaB- and gammaF-crystallin genes in lens: opposite promoter-specific interactions between Pax6 and large Maf transcription factors. Journal of Molecular Biology. 344: 351-68. PMID 15522290 DOI: 10.1016/J.Jmb.2004.07.102 |
0.543 |
|
| 2004 |
Cvekl A, Zavadil J, Birshtein BK, Grotzer MA, Cvekl A. Analysis of transcripts from 17p13.3 in medulloblastoma suggests ROX/MNT as a potential tumour suppressor gene. European Journal of Cancer (Oxford, England : 1990). 40: 2525-32. PMID 15519529 DOI: 10.1016/J.Ejca.2004.08.005 |
0.429 |
|
| 2004 |
Zaniolo K, Leclerc S, Cvekl A, Vallières L, Bazin R, Larouche K, Guérin SL. Expression of the alpha4 integrin subunit gene promoter is modulated by the transcription factor Pax-6 in corneal epithelial cells. Investigative Ophthalmology & Visual Science. 45: 1692-704. PMID 15161828 DOI: 10.1167/Iovs.03-0908 |
0.389 |
|
| 2004 |
Cvekl A, Tamm ER. Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 26: 374-86. PMID 15057935 DOI: 10.1002/Bies.20009 |
0.434 |
|
| 2004 |
Chauhan BK, Yang Y, Cveklová K, Cvekl A. Functional interactions between alternatively spliced forms of Pax6 in crystallin gene regulation and in haploinsufficiency. Nucleic Acids Research. 32: 1696-709. PMID 15020706 DOI: 10.1093/Nar/Gkh334 |
0.384 |
|
| 2004 |
Chauhan BK, Yang Y, Cveklová K, Cvekl A. Functional properties of natural human PAX6 and PAX6(5a) mutants. Investigative Ophthalmology & Visual Science. 45: 385-92. PMID 14744876 DOI: 10.1167/Iovs.03-0968 |
0.334 |
|
| 2003 |
Wu K, Yang Y, Wang C, Davoli MA, D'Amico M, Li A, Cveklova K, Kozmik Z, Lisanti MP, Russell RG, Cvekl A, Pestell RG. DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. The Journal of Biological Chemistry. 278: 51673-84. PMID 14525983 DOI: 10.1074/Jbc.M310021200 |
0.351 |
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| 2002 |
Chauhan BK, Reed NA, Yang Y, Cermák L, Reneker L, Duncan MK, Cvekl A. A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 7: 1267-83. PMID 12485166 DOI: 10.1046/J.1365-2443.2002.00602.X |
0.46 |
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| 2002 |
Baulmann DC, Ohlmann A, Flügel-Koch C, Goswami S, Cvekl A, Tamm ER. Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities. Mechanisms of Development. 118: 3-17. PMID 12351165 DOI: 10.1016/S0925-4773(02)00260-5 |
0.4 |
|
| 2002 |
Kim SS, Zhang RG, Braunstein SE, Joachimiak A, Cvekl A, Hegde RS. Structure of the retinal determination protein Dachshund reveals a DNA binding motif. Structure (London, England : 1993). 10: 787-95. PMID 12057194 DOI: 10.1016/S0969-2126(02)00769-4 |
0.393 |
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| 2002 |
Chauhan BK, Zhang W, Cveklova K, Kantorow M, Cvekl A. Identification of differentially expressed genes in mouse Pax6 heterozygous lenses. Investigative Ophthalmology & Visual Science. 43: 1884-90. PMID 12036994 |
0.367 |
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| 2002 |
Chauhan BK, Reed NA, Zhang W, Duncan MK, Kilimann MW, Cvekl A. Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays. The Journal of Biological Chemistry. 277: 11539-48. PMID 11790784 DOI: 10.1074/Jbc.M110531200 |
0.488 |
|
| 2000 |
Kirstein L, Cvekl A, Chauhan BK, Tamm ER. Regulation of human myocilin/TIGR gene transcription in trabecular meshwork cells and astrocytes: role of upstream stimulatory factor. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 5: 661-76. PMID 10947851 DOI: 10.1046/J.1365-2443.2000.00355.X |
0.455 |
|
| 1999 |
Kozmik Z, Pfeffer P, Kralova J, Paces J, Paces V, Kalousova A, Cvekl A. Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene Development Genes and Evolution. 209: 537-545. PMID 10502110 DOI: 10.1007/S004270050286 |
0.399 |
|
| 1999 |
Ilagan JG, Cvekl A, Kantorow M, Piatigorsky J, Sax CM. Regulation of αA-crystallin gene expression: Lens specificity achieved through the differential placement of similar transcriptional control elements in mouse and chicken Journal of Biological Chemistry. 274: 19973-19978. PMID 10391946 DOI: 10.1074/Jbc.274.28.19973 |
0.525 |
|
| 1998 |
Duncan MK, Haynes JI, Cvekl A, Piatigorsky J. Dual roles for Pax-6: A transcriptional repressor of lens fiber cell- specific β-crystallin genes Molecular and Cellular Biology. 18: 5579-5586. PMID 9710641 DOI: 10.1128/Mcb.18.9.5579 |
0.488 |
|
| 1998 |
Gopal-Srivastava R, Cvekl A, Piatigorsky J. Involvement of retinoic acid/retinoid receptors in the regulation of murine alphaB-crystallin/small heat shock protein gene expression in the lens. The Journal of Biological Chemistry. 273: 17954-61. PMID 9651402 DOI: 10.1074/Jbc.273.28.17954 |
0.417 |
|
| 1997 |
Li X, Cvekl A, Bassnett S, Piatigorsky J. Lens-preferred activity of chicken delta 1- and delta 2-crystallin enhancers in transgenic mice and evidence for retinoic acid-responsive regulation of the delta 1-crystallin gene. Developmental Genetics. 20: 258-66. PMID 9216065 DOI: 10.1002/(Sici)1520-6408(1997)20:3<258::Aid-Dvg8>3.0.Co;2-6 |
0.416 |
|
| 1997 |
Sax CM, Cvekl A, Piatigorsky J. Transcriptional regulation of the mouse αA-crystallin gene: Binding of USF to the -7/+5 region Gene. 185: 209-216. PMID 9055817 DOI: 10.1016/S0378-1119(96)00643-9 |
0.485 |
|
| 1996 |
Gopal-Srivastava R, Cvekl A, Piatigorsky J. Pax-6 and alphaB-crystallin/small heat shock protein gene regulation in the murine lens. Interaction with the lens-specific regions, LSR1 and LSR2. The Journal of Biological Chemistry. 271: 23029-36. PMID 8798491 DOI: 10.1074/Jbc.271.38.23029 |
0.443 |
|
| 1996 |
Cvekl A, Piatigorsky J. Lens development and crystallin gene expression: many roles for Pax-6. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 621-30. PMID 8760335 DOI: 10.1002/Bies.950180805 |
0.516 |
|
| 1996 |
McDermott JB, Cvekl A, Piatigorsky J. Lens-specific expression of a chicken beta A3/A1-crystallin promoter fragment in transgenic mice. Biochemical and Biophysical Research Communications. 221: 559-64. PMID 8630000 DOI: 10.1006/Bbrc.1996.0635 |
0.348 |
|
| 1995 |
Chambers C, Cvekl A, Sax CM, Russell P. Sequence, initial functional analysis and protein-DNA binding sites of the mouse βB2-crystallin-encoding gene Gene. 166: 287-292. PMID 8543177 DOI: 10.1016/0378-1119(95)00615-X |
0.497 |
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| 1995 |
Sax CM, Cvekl A, Kantorow M, Gopal-srivastava R, Ilagan JG, Ambulos NP, Piatigorsky J. Lens-specific activity of the mouse αA-crystallin promoter in the absence of a TATA box: Functional and protein binding analysis of the mouse (αA-crystallin PE1 region Nucleic Acids Research. 23: 442-451. PMID 7885839 DOI: 10.1093/Nar/23.3.442 |
0.5 |
|
| 1995 |
Cvekl A, Kashanchi F, Sax CM, Brady JN, Piatigorsky J. Transcriptional regulation of the mouse αA-crystallin gene: Activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site Molecular and Cellular Biology. 15: 653-660. PMID 7823934 DOI: 10.1128/Mcb.15.2.653 |
0.455 |
|
| 1995 |
Cvekl A, Sax CM, Li X, McDermott JB, Piatigorsky J. Pax-6 and lens-specific transcription of the chicken δ1-crystallin gene Proceedings of the National Academy of Sciences of the United States of America. 92: 4681-4685. PMID 7753864 DOI: 10.1073/Pnas.92.10.4681 |
0.5 |
|
| 1995 |
Richardson J, Cvekl A, Wistow G. Pax-6 is essential for lens-specific expression of zeta-crystallin. Proceedings of the National Academy of Sciences of the United States of America. 92: 4676-80. PMID 7753863 DOI: 10.1073/Pnas.92.10.4676 |
0.506 |
|
| 1995 |
Cvekl A, McDermott JB, Piatigorsky J. cDNA encoding a chicken protein (CRP1) with homology to hnRNP type A/B. Biochimica Et Biophysica Acta. 1261: 290-2. PMID 7711075 DOI: 10.1016/0167-4781(95)00021-8 |
0.308 |
|
| 1995 |
Duvall JF, Kashanchi F, Cvekl A, Radonovich MF, Piras G, Brady JN. Transactivation of the human T-cell lymphotropic virus type 1 Tax1-responsive 21-base-pair repeats requires Holo-TFIID and TFIIA. Journal of Virology. 69: 5077-86. PMID 7609077 DOI: 10.1128/Jvi.69.8.5077-5086.1995 |
0.403 |
|
| 1994 |
Sax CM, Cvekl A, Kantorow M, Sommer B, Chepelinsky AB, Piatigorsky J. Identification of negative-acting and protein-binding elements in the mouse αA-crystallin -1556/-1165 region Gene. 144: 163-169. PMID 8039701 DOI: 10.1016/0378-1119(94)90374-3 |
0.473 |
|
| 1994 |
Cvekl A, Sax CM, Bresnick EH, Piatigorsky J. A complex array of positive and negative elements regulates the chicken αA-crystallin gene: Involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins Molecular and Cellular Biology. 14: 7363-7376. PMID 7935450 DOI: 10.1128/Mcb.14.11.7363 |
0.427 |
|
| 1994 |
Tomarev SI, Duncan MK, Roth HJ, Cvekl A, Piatigorsky J. Convergent evolution of crystallin gene regulation in squid and chicken: the AP-1/ARE connection. Journal of Molecular Evolution. 39: 134-43. PMID 7932777 DOI: 10.1007/BF00163802 |
0.327 |
|
| 1993 |
Kantorow M, Cvekl A, Sax CM, Piatigorsky J. Protein-DNA interactions of the mouse αA-crystallin control regions: Differences between expressing and non-expressing cells Journal of Molecular Biology. 230: 425-435. PMID 8464058 DOI: 10.1006/Jmbi.1993.1160 |
0.434 |
|
| 1992 |
Cvekl A, Pačes V. Interactions between proteins bound to the duck βA-globin gene promoter and enhancer detected by the DNaseI footprinting Gene. 110: 225-228. PMID 1537559 DOI: 10.1016/0378-1119(92)90652-6 |
0.35 |
|
| 1992 |
Piatigorsky J, Kantorow M, Cvekl A, Sax CM, Gopal-Srivastava R, Frederikse P. Molecular analysis of mouse αA- and αB-crystallin gene expression in lens and non-lens cells Experimental Eye Research. 55: 222. DOI: 10.1016/0014-4835(92)90994-4 |
0.454 |
|
| 1991 |
Cvekl A, Horská K, Vlček C, P`ačes V. Protein-binding A + T-rich motifs flank the duck βA-globin enhancer Gene. 103: 253-257. PMID 1889750 DOI: 10.1016/0378-1119(91)90282-G |
0.32 |
|
| 1990 |
Schnapp A, Clos J, Hädelt W, Schreck R, Cvekl A, Grummt I. Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I Nucleic Acids Research. 18: 1385-1393. PMID 2326184 DOI: 10.1093/Nar/18.6.1385 |
0.413 |
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