Dennis D. Cunningham - Publications

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Molecular Biology

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2002 Pai KS, Cunningham DD. Geldanamycin specifically modulates thrombin-mediated morphological changes in mouse neuroblasts. Journal of Neurochemistry. 80: 715-8. PMID 11841578 DOI: 10.1046/J.0022-3042.2001.00761.X  0.386
2001 Pai KS, Mahajan VB, Lau A, Cunningham DD. Thrombin receptor signaling to cytoskeleton requires Hsp90. The Journal of Biological Chemistry. 276: 32642-7. PMID 11413145 DOI: 10.1074/Jbc.M104212200  0.57
2000 Mahajan VB, Pai KS, Lau A, Cunningham DD. Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America. 97: 12062-7. PMID 11050237 DOI: 10.1073/Pnas.97.22.12062  0.589
1998 Weinstein JR, Lau AL, Brass LF, Cunningham DD. Injury-related factors and conditions down-regulate the thrombin receptor (PAR-1) in a human neuronal cell line. Journal of Neurochemistry. 71: 1034-50. PMID 9721728 DOI: 10.1046/J.1471-4159.1998.71031034.X  0.449
1998 Donovan FM, Cunningham DD. Signaling pathways involved in thrombin-induced cell protection. The Journal of Biological Chemistry. 273: 12746-52. PMID 9582299 DOI: 10.1074/Jbc.273.21.12746  0.386
1997 Guttridge DC, Lau A, Tran L, Cunningham DD. Thrombin causes a marked delay in skeletal myogenesis that correlates with the delayed expression of myogenin and p21CIP1/WAF1. The Journal of Biological Chemistry. 272: 24117-20. PMID 9305855 DOI: 10.1074/Jbc.272.39.24117  0.349
1997 Donovan FM, Pike CJ, Cotman CW, Cunningham DD. Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5316-26. PMID 9204916 DOI: 10.1523/Jneurosci.17-14-05316.1997  0.427
1996 Guttridge DC, Cunningham DD. Characterization of the human protease nexin-1 promoter and its regulation by Sp1 through a G/C-rich activation domain. Journal of Neurochemistry. 67: 498-507. PMID 8764573 DOI: 10.1046/J.1471-4159.1996.67020498.X  0.305
1996 Pike CJ, Vaughan PJ, Cunningham DD, Cotman CW. Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro. Journal of Neurochemistry. 66: 1374-82. PMID 8627288 DOI: 10.1046/J.1471-4159.1996.66041374.X  0.323
1995 Grabham P, Cunningham DD. Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. Journal of Neurochemistry. 64: 583-91. PMID 7830051 DOI: 10.1046/J.1471-4159.1995.64020583.X  0.438
1995 Weinstein JR, Gold SJ, Cunningham DD, Gall CM. Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 2906-19. PMID 7722637 DOI: 10.1523/Jneurosci.15-04-02906.1995  0.378
1995 Vaughan PJ, Pike CJ, Cotman CW, Cunningham DD. Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5389-401. PMID 7623161 DOI: 10.1523/Jneurosci.15-07-05389.1995  0.38
1994 Vaughan PJ, Su J, Cotman CW, Cunningham DD. Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain Research. 668: 160-70. PMID 7704602 DOI: 10.1016/0006-8993(94)90521-5  0.331
1993 Wagner SL, Van Nostrand WE, Lau AL, Farrow JS, Suzuki M, Bartus RT, Schuppek R, Nguyen A, Cotman CW, Cunningham DD. Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates. Brain Research. 626: 90-8. PMID 8281456 DOI: 10.1016/0006-8993(93)90567-7  0.348
1992 Cunningham DD, Wagner SL, Farrell DH. Regulation of protease nexin-1 activity by heparin and heparan sulfate. Advances in Experimental Medicine and Biology. 313: 297-306. PMID 1442266 DOI: 10.1007/978-1-4899-2444-5_29  0.47
1992 Kim T, Choi BH, Choe W, Kim RC, Van Nostrand W, Wagner S, Cunningham D. Expression of protease nexin-II in human dorsal root ganglia. A correlative immunocytochemical and in situ hybridization study. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 16: 225-39. PMID 1418219 DOI: 10.1007/Bf03159972  0.32
1992 Cummings BJ, Su JH, Geddes JW, Van Nostrand WE, Wagner SL, Cunningham DD, Cotman CW. Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience. 48: 763-77. PMID 1378573 DOI: 10.1016/0306-4522(92)90265-4  0.309
1992 Cunningham DD. Regulation of neuronal cells and astrocytes by protease nexin-1 and thrombin. Annals of the New York Academy of Sciences. 674: 228-36. PMID 1288365 DOI: 10.1111/J.1749-6632.1992.Tb27491.X  0.351
1991 Dihanich M, Kaser M, Reinhard E, Cunningham D, Monard D. Prothrombin mRNA is expressed by cells of the nervous system. Neuron. 6: 575-81. PMID 2015093 DOI: 10.1016/0896-6273(91)90060-D  0.352
1991 Wagner SL, Lau AL, Nguyen A, Mimuro J, Loskutoff DJ, Isackson PJ, Cunningham DD. Inhibitors of urokinase and thrombin in cultured neural cells. Journal of Neurochemistry. 56: 234-42. PMID 1987320 DOI: 10.1111/J.1471-4159.1991.Tb02586.X  0.475
1991 Van Nostrand WE, Farrow JS, Wagner SL, Bhasin R, Goldgaber D, Cotman CW, Cunningham DD. The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2. Proceedings of the National Academy of Sciences of the United States of America. 88: 10302-6. PMID 1946448 DOI: 10.1073/Pnas.88.22.10302  0.318
1991 Van Nostrand WE, Schmaier AH, Farrow JS, Cines DB, Cunningham DD. Protease nexin-2/amyloid beta-protein precursor in blood is a platelet-specific protein. Biochemical and Biophysical Research Communications. 175: 15-21. PMID 1900151 DOI: 10.1016/S0006-291X(05)81193-3  0.385
1991 Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. Platelet protease nexin-2/amyloid beta-protein precursor. Possible pathologic and physiologic functions. Annals of the New York Academy of Sciences. 640: 140-4. PMID 1776731 DOI: 10.1111/J.1749-6632.1991.Tb00205.X  0.351
1990 Gurwitz D, Cunningham DD. Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition. Journal of Cellular Physiology. 142: 155-62. PMID 2298818 DOI: 10.1002/Jcp.1041420119  0.461
1990 Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein. Science (New York, N.Y.). 248: 745-8. PMID 2110384 DOI: 10.1126/Science.2110384  0.325
1990 Cavanaugh KP, Gurwitz D, Cunningham DD, Bradshaw RA. Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. Journal of Neurochemistry. 54: 1735-43. PMID 1691280 DOI: 10.1111/J.1471-4159.1990.Tb01228.X  0.418
1989 Wagner SL, Geddes JW, Cotman CW, Lau AL, Gurwitz D, Isackson PJ, Cunningham DD. Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 86: 8284-8. PMID 2813392 DOI: 10.1073/Pnas.86.21.8284  0.358
1989 Gurwitz D, Simon MM, Fruth U, Cunningham DD. Protease nexin-1 complexes and inhibits T cell serine proteinase-1. Biochemical and Biophysical Research Communications. 161: 300-4. PMID 2786418 DOI: 10.1016/0006-291X(89)91596-9  0.376
1989 Cunningham DD, Gurwitz D. Proteolytic regulation of neurite outgrowth from neuroblastoma cells by thrombin and protease nexin-1. Journal of Cellular Biochemistry. 39: 55-64. PMID 2654147 DOI: 10.1002/Jcb.240390107  0.438
1989 Van Nostrand WE, Wagner SL, Suzuki M, Choi BH, Farrow JS, Geddes JW, Cotman CW, Cunningham DD. Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature. 341: 546-9. PMID 2507928 DOI: 10.1038/341546A0  0.355
1988 Hiramoto SA, Cunningham DD. Effects of fibroblasts and endothelial cells on inactivation of target proteases by protease nexin-1, heparin cofactor II, and C1-inhibitor. Journal of Cellular Biochemistry. 36: 199-207. PMID 3379101 DOI: 10.1002/Jcb.240360302  0.408
1988 Van Nostrand WE, Wagner SL, Cunningham DD. Purification of a form of protease nexin 1 that binds heparin with a low affinity. Biochemistry. 27: 2176-81. PMID 3378053 DOI: 10.1021/Bi00406A054  0.321
1988 Wagner SL, Van Nostrand WE, Lau AL, Cunningham DD. Monoclonal antibodies to protease nexin 1 that differentially block its inhibition of target proteases. Biochemistry. 27: 2173-6. PMID 3378052 DOI: 10.1021/Bi00406A053  0.371
1988 Farrell DH, Wagner SL, Yuan RH, Cunningham DD. Localization of protease nexin-1 on the fibroblast extracellular matrix. Journal of Cellular Physiology. 134: 179-88. PMID 3279057 DOI: 10.1002/Jcp.1041340203  0.416
1988 Gurwitz D, Cunningham DD. Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 85: 3440-4. PMID 2835773 DOI: 10.1073/Pnas.85.10.3440  0.441
1987 Van Nostrand WE, Cunningham DD. Purification of a proteinase inhibitor from bovine serum with C1-inhibitor activity. Biochimica Et Biophysica Acta. 923: 167-75. PMID 3814612 DOI: 10.1016/0304-4165(87)90001-8  0.345
1987 Thompson JA, Cunningham DD. Identification of cell surface proteins sensitive to proteolysis by thrombin. Methods in Enzymology. 147: 157-64. PMID 3670082 DOI: 10.1016/0076-6879(87)47107-3  0.331
1987 Campbell CH, Cunningham DD. Binding sites for elastase on cultured human fibroblasts that do not mediate internalization. Journal of Cellular Physiology. 130: 142-9. PMID 3643217 DOI: 10.1002/Jcp.1041300120  0.399
1987 Thompson JA, Lau AL, Cunningham DD. Selective radiolabeling of cell surface proteins to a high specific activity. Biochemistry. 26: 743-50. PMID 3552030 DOI: 10.1021/Bi00377A014  0.358
1987 Raben DM, Yasuda K, Cunningham DD. Modulation of thrombin-stimulated lipid responses in cultured fibroblasts. Evidence for two coupling mechanisms. Biochemistry. 26: 2759-65. PMID 3111524 DOI: 10.1021/Bi00384A016  0.337
1987 Raben DM, Yasuda KM, Cunningham DD. Relationship of thrombin-stimulated arachidonic acid release and metabolism to mitogenesis and phosphatidylinositol synthesis. Journal of Cellular Physiology. 130: 466-73. PMID 3104353 DOI: 10.1002/Jcp.1041300322  0.335
1987 Farrell DH, Cunningham DD. Glycosaminoglycans on fibroblasts accelerate thrombin inhibition by protease nexin-1. The Biochemical Journal. 245: 543-50. PMID 2959275 DOI: 10.1042/Bj2450543  0.449
1986 Cunningham DD, Van Nostrand WE, Farrell DH, Campbell CH. Interactions of serine proteases with cultured fibroblasts. Journal of Cellular Biochemistry. 32: 281-91. PMID 3543029 DOI: 10.1002/Jcb.240320405  0.426
1986 Farrell DH, Cunningham DD. Human fibroblasts accelerate the inhibition of thrombin by protease nexin. Proceedings of the National Academy of Sciences of the United States of America. 83: 6858-62. PMID 3462733 DOI: 10.1073/Pnas.83.18.6858  0.45
1986 Farrell DH, Van Nostrand WE, Cunningham DD. A simple two-step purification of protease nexin. The Biochemical Journal. 237: 907-12. PMID 3099760 DOI: 10.1042/Bj2370907  0.41
1985 Raben DM, Cunningham DD. Effects of EGF and thrombin on inositol-containing phospholipids of cultured fibroblasts: stimulation of phosphatidylinositol synthesis by thrombin but not EGF. Journal of Cellular Physiology. 125: 582-90. PMID 2999166 DOI: 10.1002/Jcp.1041250330  0.353
1984 Knauer DJ, Cunningham DD. Protease nexins: cell-secreted proteins which regulate extracellular serine proteases Trends in Biochemical Sciences. 9: 231-233. DOI: 10.1016/0968-0004(84)90074-4  0.471
1983 Knauer DJ, Cunningham DD. A reevaluation of the response of human umbilical vein endothelial cells to certain growth factors. Journal of Cellular Physiology. 117: 397-406. PMID 6317701 DOI: 10.1002/Jcp.1041170315  0.391
1983 Knauer DJ, Thompson JA, Cunningham DD. Protease nexins: cell-secreted proteins that mediate the binding, internalization, and degradation of regulatory serine proteases. Journal of Cellular Physiology. 117: 385-96. PMID 6317700 DOI: 10.1002/Jcp.1041170314  0.446
1983 Cunningham DD, Knauer DJ. Protease nexins and control of cell proliferation Cell Biology International Reports. 7: 497-498. DOI: 10.1016/0309-1651(83)90146-7  0.37
1982 Baker JB, Low DA, Eaton DL, Cunningham DD. Thrombin-mediated mitogenesis: the role of secreted protease nexin. Journal of Cellular Physiology. 112: 291-7. PMID 7119026 DOI: 10.1002/Jcp.1041120220  0.412
1982 Low DA, Cunningham DD. The effects of cell-released protease nexin on the measurement of thrombin binding to mouse cells. Biochemical and Biophysical Research Communications. 105: 667-73. PMID 7092878 DOI: 10.1016/0006-291X(82)91486-3  0.428
1982 Low DA, Scott RW, Baker JB, Cunningham DD. Cells regulate their mitogenic response to thrombin through release of protease nexin. Nature. 298: 476-8. PMID 7088192 DOI: 10.1038/298476A0  0.503
1982 Knauer DJ, Cunningham DD. Epidermal growth factor carrier protein binds to cells via a complex with released carried protein nexin. Proceedings of the National Academy of Sciences of the United States of America. 79: 2310-4. PMID 6980418 DOI: 10.1073/Pnas.79.7.2310  0.454
1982 Wiley HS, Cunningham DD. Epidermal growth factor stimulates fluid phase endocytosis in human fibroblasts through a signal generated at the cell surface. Journal of Cellular Biochemistry. 19: 383-94. PMID 6298257 DOI: 10.1002/Jcb.240190407  0.374
1981 Moss M, Cunningham DD. Cleavage of cell surface proteins by thrombin. Journal of Supramolecular Structure and Cellular Biochemistry. 15: 49-61. PMID 7253649 DOI: 10.1002/Jsscb.1981.380150106  0.412
1981 Low DA, Baker JB, Koonce WC, Cunningham DD. Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases. Proceedings of the National Academy of Sciences of the United States of America. 78: 2340-4. PMID 7017731 DOI: 10.1073/Pnas.78.4.2340  0.416
1981 Shuman MA, Isaacs JD, Maerowitz T, Savion N, Gospodarowicz D, Glenn K, Cunningham D, Fenton JW. Endothelial cell and platelet binding sites for thrombin. Annals of the New York Academy of Sciences. 370: 57-66. PMID 6943971 DOI: 10.1111/J.1749-6632.1981.Tb29721.X  0.357
1981 Wiley HS, Cunningham DD. A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands. Cell. 25: 433-40. PMID 6269748 DOI: 10.1016/0092-8674(81)90061-1  0.309
1980 Baker JB, Low DA, Simmer RL, Cunningham DD. Protease-nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells. Cell. 21: 37-45. PMID 6157479 DOI: 10.1016/0092-8674(80)90112-9  0.459
1979 Carney DH, Cunningham DD. Transmembrane action of thrombin initiates chick cell division Journal of Supramolecular and Cellular Biochemistry. 9: 337-350. PMID 748680 DOI: 10.1002/Jss.400090305  0.449
1979 Cunningham DD, Glenn KC, Baker JB, Simmer RL, Low DA. Mechanisms of thrombin-stimulated cell division. Journal of Supramolecular Structure. 11: 259-67. PMID 548651 DOI: 10.1002/Jss.400110215  0.409
1979 Simmer RL, Baker JB, Cunningham DD. Direct linkage of thrombin to its cell surface receptors in different cell types. Journal of Supramolecular Structure. 12: 245-57. PMID 544938 DOI: 10.1002/Jss.400120209  0.388
1979 Baker JB, Simmer RL, Glenn KC, Cunningham DD. Glucocorticoids enhance the mitogenic action of insulin in serum-free cultures of chick embryo cells. Journal of Cellular Physiology. 98: 561-70. PMID 438300 DOI: 10.1002/Jcp.1040980314  0.332
1979 Glenn KC, Cunningham DD. Thrombin-stimulated cell division involves proteolysis of its cell surface receptor. Nature. 278: 711-4. PMID 431729 DOI: 10.1038/278711A0  0.415
1979 Baker JB, Simmer RL, Glenn KC, Cunningham DD. Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation. Nature. 278: 743-5. PMID 219372 DOI: 10.1038/278743A0  0.408
1978 Carney DH, Cunningham DD. Role of specific cell surface receptors in thrombin-stimulated cell division. Cell. 15: 1341-9. PMID 729002 DOI: 10.1016/0092-8674(78)90059-4  0.453
1978 Carney DH, Cunningham DD. Cell surface action of thrombin is sufficient to initiate division of chick cells. Cell. 14: 811-23. PMID 688395 DOI: 10.1016/0092-8674(78)90337-9  0.427
1978 Carney DH, Glenn KC, Cunningham DD. Conditions which affect initiation of animal cell division by trypsin and thrombin. Journal of Cellular Physiology. 95: 13-22. PMID 565362 DOI: 10.1002/Jcp.1040950103  0.439
1978 Baker JB, Barsh GS, Carney DH, Cunningham DD. Dexamethasone modulates binding and action of epidermal growth factor in serum-free cell culture. Proceedings of the National Academy of Sciences of the United States of America. 75: 1882-6. PMID 306107 DOI: 10.1073/Pnas.75.4.1882  0.452
1978 Baker JB, Cunningham DD. Glucocorticoid-mediated alteration in growth factor binding and action: analysis of the binding change. Journal of Supramolecular Structure. 9: 69-77. PMID 215839 DOI: 10.1002/Jss.400090108  0.422
1977 Carney DH, Cunningham DD. Initiation of chick cell division by trypsin action at the cell surface Nature. 268: 602-606. PMID 561313 DOI: 10.1038/268602A0  0.438
1977 Barsh GS, Greenberg DB, Cunningham DD. Phosphate uptake and control of fibroblasts growth. Journal of Cellular Physiology. 92: 115-28. PMID 561075 DOI: 10.1002/Jcp.1040920114  0.408
1977 Naiditch WP, Cunningham DD. Hexose uptake and control of fibroblast proliferation Journal of Cellular Physiology. 92: 319-332. PMID 560379 DOI: 10.1002/Jcp.1040920221  0.32
1977 Breenberg DB, Barsh GS, Ho TS, Cunningham DD. Serum-stimulated phosphate uptake and initiation of fibroblast proliferation. Journal of Cellular Physiology. 90: 193-210. PMID 557045 DOI: 10.1002/Jcp.1040900206  0.352
1977 Barsh GS, Cunningham DD. Nutrient uptake and control of animal cell proliferation. Journal of Supramolecular Structure. 7: 61-77. PMID 342831 DOI: 10.1002/Jss.400070107  0.389
1975 Thrash CR, Cunningham DD. Growth limitation of 3T3 mouse fibroblasts by available growth surface area and medium components Journal of Cellular Physiology. 86. PMID 1194367 DOI: 10.1002/Jcp.1040860214  0.359
1974 Thrash CR, Cunningham DD. Dissociation of increased hexose transport from initiation of fibroblast proliferation Nature. 252: 45-47. PMID 4139660 DOI: 10.1038/252045A0  0.331
1973 Glynn RD, Thrash CR, Cunningham DD. Maximal concanavalin A specific agglutinability without loss of density dependent growth control (3T3 cells/Pronase) Proceedings of the National Academy of Sciences of the United States of America. 70: 2676-2677. PMID 4517678 DOI: 10.1073/Pnas.70.9.2676  0.409
1973 Thrash CR, Cunningham DD. Stimulation of division of density inhibited fibroblasts glucocorticoids Nature. 242: 399-401. PMID 4349600 DOI: 10.1038/242399A0  0.436
1969 Cunningham DD, Pardee AB. Transport changes rapidly initiated by serum addition to "contact inhibited" 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. 64: 1049-1056. PMID 4313331 DOI: 10.1073/Pnas.64.3.1049  0.367
Show low-probability matches.