| Year |
Citation |
Score |
| 2021 |
Salamina M, Montefiore BC, Liu M, Wood DJ, Heath R, Ault JR, Wang LZ, Korolchuk S, Baslé A, Pastok MW, Reeks J, Tatum NJ, Sobott F, Arold ST, Pagano M, et al. Discriminative SKP2 interactions with CDK-cyclin complexes supportacyclin A-specificrole in p27KIP1 degradation. Journal of Molecular Biology. 166795. PMID 33422522 DOI: 10.1016/j.jmb.2020.166795 |
0.3 |
|
| 2020 |
Tsunematsu T, Arakaki R, Kawai H, Ruppert J, Tsuneyama K, Ishimaru N, Earnshaw WC, Pagano M, Kudo Y. APC/C is required for the termination of chromosomal passenger complex activity upon mitotic exit. Journal of Cell Science. 133. PMID 32934012 DOI: 10.1242/Jcs.251314 |
0.362 |
|
| 2020 |
Moro L, Simoneschi D, Kurz E, Arbini AA, Jang S, Guaragnella N, Giannattasio S, Wang W, Chen YA, Pires G, Dang A, Hernandez E, Kapur P, Mishra A, Tsirigos A, ... ... Pagano M, et al. Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis. Nature Cell Biology. PMID 32839549 DOI: 10.1038/S41556-020-0560-6 |
0.337 |
|
| 2020 |
Reynders M, Matsuura BS, Bérouti M, Simoneschi D, Marzio A, Pagano M, Trauner D. PHOTACs enable optical control of protein degradation. Science Advances. 6: eaay5064. PMID 32128406 DOI: 10.1126/Sciadv.Aay5064 |
0.357 |
|
| 2019 |
Rona G, Pagano M. Mixed ubiquitin chains regulate DNA repair. Genes & Development. 33: 1615-1616. PMID 31792015 DOI: 10.1101/Gad.334383.119 |
0.309 |
|
| 2019 |
Kuchay S, Wang H, Marzio A, Jain K, Homer H, Fehrenbacher N, Philips MR, Zheng N, Pagano M. GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase. Nature Structural & Molecular Biology. PMID 31209342 DOI: 10.1038/S41594-019-0249-3 |
0.746 |
|
| 2019 |
Rizzini L, Levine DC, Perelis M, Bass J, Peek CB, Pagano M. Cryptochromes-Mediated Inhibition of the CRL4-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism. Current Biology : Cb. PMID 31155351 DOI: 10.1016/J.Cub.2019.04.073 |
0.358 |
|
| 2019 |
Cuitiño MC, Pécot T, Sun D, Kladney R, Okano-Uchida T, Shinde N, Saeed R, Perez-Castro AJ, Webb A, Liu T, Bae SI, Clijsters L, Selner N, Coppola V, Timmers C, ... ... Pagano M, et al. Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. Cell Reports. PMID 31130414 DOI: 10.1016/J.Celrep.2019.05.004 |
0.387 |
|
| 2019 |
Clijsters L, Hoencamp C, Calis JJA, Marzio A, Handgraaf SM, Cuitino MC, Rosenberg BR, Leone G, Pagano M. Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Molecular Cell. PMID 31130363 DOI: 10.1016/J.Molcel.2019.04.010 |
0.414 |
|
| 2018 |
Jeong YT, Simoneschi D, Keegan S, Melville D, Adler NS, Saraf A, Florens L, Washburn MP, Cavasotto CN, Fenyö D, Cuervo AM, Rossi M, Pagano M. The ULK1-FBXW5-SEC23B nexus controls autophagy. Elife. 7. PMID 30596474 DOI: 10.7554/Elife.42253 |
0.403 |
|
| 2018 |
Marzio A, Puccini J, Kwon Y, Maverakis NK, Arbini A, Sung P, Bar-Sagi D, Pagano M. The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers. Molecular Cell. PMID 30554948 DOI: 10.1016/J.Molcel.2018.11.003 |
0.344 |
|
| 2018 |
Kuchay S, Saeed M, Giorgi C, Li J, Hoffmann HH, Pinton P, Rice CM, Pagano M. NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus. Cell Reports. 25: 833-840.e3. PMID 30355490 DOI: 10.1016/J.Celrep.2018.09.088 |
0.721 |
|
| 2018 |
Mavrommati I, Faedda R, Galasso G, Li J, Burdova K, Fischer R, Kessler BM, Carrero ZI, Guardavaccaro D, Pagano M, D'Angiolella V. β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression. Cell Reports. 24: 3404-3412. PMID 30257202 DOI: 10.1016/J.Celrep.2018.08.076 |
0.42 |
|
| 2018 |
Rona G, Roberti D, Yin Y, Pagan JK, Homer H, Sassani E, Zeke A, Busino L, Rothenberg E, Pagano M. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. Elife. 7. PMID 29985131 DOI: 10.7554/Elife.38771 |
0.332 |
|
| 2017 |
Pae J, Cinalli RM, Marzio A, Pagano M, Lehmann R. GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK. Developmental Cell. 42: 130-142.e7. PMID 28743001 DOI: 10.1016/J.Devcel.2017.06.022 |
0.434 |
|
| 2017 |
Fehrenbacher N, Tojal da Silva I, Ramirez C, Zhou Y, Cho KJ, Kuchay S, Shi J, Thomas S, Pagano M, Hancock JF, Bar-Sagi D, Philips MR. The G protein-coupled receptor GPR31 promotes membrane association of KRAS. The Journal of Cell Biology. PMID 28619714 DOI: 10.1083/Jcb.201609096 |
0.722 |
|
| 2017 |
Kuchay S, Giorgi C, Simoneschi D, Pagan J, Missiroli S, Saraf A, Florens L, Washburn MP, Collazo-Lorduy A, Castillo-Martin M, Cordon-Cardo C, Sebti SM, Pinton P, Pagano M. PTEN counteracts FBXL2 to promote IP3R3- and Ca(2+)-mediated apoptosis limiting tumour growth. Nature. PMID 28614300 DOI: 10.1038/Nature22965 |
0.739 |
|
| 2017 |
Dankert JF, Pagan JK, Starostina NG, Kipreos ET, Pagano M. FEM1 proteins are ancient regulators of SLBP degradation. Cell Cycle (Georgetown, Tex.). 0. PMID 28118078 DOI: 10.1080/15384101.2017.1284715 |
0.465 |
|
| 2017 |
Duan S, Pagano M. FBXO11 (F-box protein 11) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/62321 |
0.311 |
|
| 2016 |
Signoretti S, Di Marcotullio L, Richardson A, Ramaswamy S, Isaac B, Rue M, Monti F, Loda M, Pagano M. Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. The Journal of Clinical Investigation. 126: 4387. PMID 27801677 DOI: 10.1172/Jci15795 |
0.356 |
|
| 2016 |
Dankert JF, Rona G, Clijsters L, Geter P, Skaar JR, Bermudez-Hernandez K, Sassani E, Fenyö D, Ueberheide B, Schneider R, Pagano M. Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2. Molecular Cell. PMID 27773672 DOI: 10.1016/J.Molcel.2016.09.010 |
0.384 |
|
| 2015 |
Young LM, Marzio A, Perez-Duran P, Reid DA, Meredith DN, Roberti D, Star A, Rothenberg E, Ueberheide B, Pagano M. TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response. Cell Reports. 13: 451-9. PMID 26456830 DOI: 10.1016/J.Celrep.2015.09.017 |
0.325 |
|
| 2015 |
Skaar JR, Ferris AL, Wu X, Saraf A, Khanna KK, Florens L, Washburn MP, Hughes SH, Pagano M. The Integrator complex controls the termination of transcription at diverse classes of gene targets. Cell Research. 25: 288-305. PMID 25675981 DOI: 10.1038/Cr.2015.19 |
0.331 |
|
| 2015 |
Pagan JK, Marzio A, Jones MJ, Saraf A, Jallepalli PV, Florens L, Washburn MP, Pagano M. Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing. Nature Cell Biology. 17: 31-43. PMID 25503564 DOI: 10.1038/Ncb3076 |
0.458 |
|
| 2014 |
Skaar JR, Pagan JK, Pagano M. SCF ubiquitin ligase-targeted therapies. Nature Reviews. Drug Discovery. 13: 889-903. PMID 25394868 DOI: 10.1038/Nrd4432 |
0.421 |
|
| 2014 |
Chen X, Sahasrabuddhe AA, Szankasi P, Chung F, Basrur V, Rangnekar VM, Pagano M, Lim MS, Elenitoba-Johnson KSJ. Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival Cell Death and Differentiation. 21: 1535-1545. PMID 24992930 DOI: 10.1038/Cdd.2014.92 |
0.406 |
|
| 2014 |
Choi BH, Pagano M, Huang C, Dai W. Cdh1, a substrate-recruiting component of anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, specifically interacts with phosphatase and tensin homolog (PTEN) and promotes its removal from chromatin. The Journal of Biological Chemistry. 289: 17951-9. PMID 24811168 DOI: 10.1074/Jbc.M114.559005 |
0.397 |
|
| 2014 |
Choi BH, Pagano M, Dai W. Plk1 protein phosphorylates phosphatase and tensin homolog (PTEN) and regulates its mitotic activity during the cell cycle. The Journal of Biological Chemistry. 289: 14066-74. PMID 24706748 DOI: 10.1074/Jbc.M114.558155 |
0.437 |
|
| 2014 |
Horn M, Geisen C, Cermak L, Becker B, Nakamura S, Klein C, Pagano M, Antebi A. DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation. Developmental Cell. 28: 697-710. PMID 24613396 DOI: 10.1016/J.Devcel.2014.01.028 |
0.403 |
|
| 2014 |
Bassermann F, Eichner R, Pagano M. The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer. Biochimica Et Biophysica Acta. 1843: 150-62. PMID 23466868 DOI: 10.1016/J.Bbamcr.2013.02.028 |
0.447 |
|
| 2013 |
Tsunematsu T, Takihara Y, Ishimaru N, Pagano M, Takata T, Kudo Y. Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis. Nature Communications. 4: 1885. PMID 23695679 DOI: 10.1038/Ncomms2859 |
0.369 |
|
| 2013 |
Skaar JR, Pagan JK, Pagano M. Mechanisms and function of substrate recruitment by F-box proteins. Nature Reviews. Molecular Cell Biology. 14: 369-81. PMID 23657496 DOI: 10.1038/Nrm3582 |
0.394 |
|
| 2013 |
Kuchay S, Duan S, Schenkein E, Peschiaroli A, Saraf A, Florens L, Washburn MP, Pagano M. FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade. Nature Cell Biology. 15: 472-80. PMID 23604317 DOI: 10.1038/Ncb2731 |
0.777 |
|
| 2013 |
Pagan J, Seto T, Pagano M, Cittadini A. Role of the ubiquitin proteasome system in the heart. Circulation Research. 112: 1046-58. PMID 23538275 DOI: 10.1161/Circresaha.112.300521 |
0.307 |
|
| 2013 |
Xing W, Busino L, Hinds TR, Marionni ST, Saifee NH, Bush MF, Pagano M, Zheng N. SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature. 496: 64-8. PMID 23503662 DOI: 10.1038/Nature11964 |
0.396 |
|
| 2013 |
Li J, D'Angiolella V, Seeley ES, Kim S, Kobayashi T, Fu W, Campos EI, Pagano M, Dynlacht BD. USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110. Nature. 495: 255-9. PMID 23486064 DOI: 10.1038/Nature11941 |
0.466 |
|
| 2013 |
Rossi M, Duan S, Jeong YT, Horn M, Saraf A, Florens L, Washburn MP, Antebi A, Pagano M. Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase. Molecular Cell. 49: 1159-66. PMID 23478441 DOI: 10.1016/J.Molcel.2013.02.004 |
0.464 |
|
| 2013 |
Jeong YT, Rossi M, Cermak L, Saraf A, Florens L, Washburn MP, Sung P, Schildkraut CL, Schildkraut C, Pagano M. FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. The Journal of Cell Biology. 200: 141-9. PMID 23319600 DOI: 10.1083/Jcb.201209002 |
0.318 |
|
| 2013 |
Fernández-Sáiz V, Targosz BS, Lemeer S, Eichner R, Langer C, Bullinger L, Reiter C, Slotta-Huspenina J, Schroeder S, Knorn AM, Kurutz J, Peschel C, Pagano M, Kuster B, Bassermann F. SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma. Nature Cell Biology. 15: 72-81. PMID 23263282 DOI: 10.1038/Ncb2651 |
0.414 |
|
| 2013 |
D'Angiolella V, Esencay M, Pagano M. A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis. Trends in Cell Biology. 23: 135-40. PMID 23182110 DOI: 10.1016/J.Tcb.2012.10.011 |
0.405 |
|
| 2012 |
Wu L, Grigoryan AV, Li Y, Hao B, Pagano M, Cardozo TJ. Specific small molecule inhibitors of Skp2-mediated p27 degradation. Chemistry & Biology. 19: 1515-24. PMID 23261596 DOI: 10.1016/J.Chembiol.2012.09.015 |
0.438 |
|
| 2012 |
Busino L, Millman SE, Pagano M. SCF-mediated degradation of p100 (NF-κB2): mechanisms and relevance in multiple myeloma. Science Signaling. 5: pt14. PMID 23211527 DOI: 10.1126/Scisignal.2003408 |
0.799 |
|
| 2012 |
Kim DS, Zhang W, Millman SE, Hwang BJ, Kwon SJ, Clayberger C, Pagano M, Krensky AM. Fbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes. Blood. 120: 1658-67. PMID 22797700 DOI: 10.1182/Blood-2012-03-415968 |
0.793 |
|
| 2012 |
Kruiswijk F, Yuniati L, Magliozzi R, Low TY, Lim R, Bolder R, Mohammed S, Proud CG, Heck AJ, Pagano M, Guardavaccaro D. Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress. Science Signaling. 5: ra40. PMID 22669845 DOI: 10.1126/scisignal.2002718 |
0.362 |
|
| 2012 |
D'Angiolella V, Donato V, Forrester FM, Jeong YT, Pellacani C, Kudo Y, Saraf A, Florens L, Washburn MP, Pagano M. Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair. Cell. 149: 1023-34. PMID 22632967 DOI: 10.1016/J.Cell.2012.03.043 |
0.364 |
|
| 2012 |
Ping Z, Lim R, Bashir T, Pagano M, Guardavaccaro D. APC/C (Cdh1) controls the proteasome-mediated degradation of E2F3 during cell cycle exit. Cell Cycle (Georgetown, Tex.). 11: 1999-2005. PMID 22580460 DOI: 10.4161/Cc.20402 |
0.435 |
|
| 2012 |
Busino L, Millman SE, Scotto L, Kyratsous CA, Basrur V, O'Connor O, Hoffmann A, Elenitoba-Johnson KS, Pagano M. Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma. Nature Cell Biology. 14: 375-85. PMID 22388891 DOI: 10.1038/Ncb2463 |
0.821 |
|
| 2012 |
Yang F, Hu L, Chen C, Yu J, O'Connell CB, Khodjakov A, Pagano M, Dai W. BubR1 is modified by sumoylation during mitotic progression. The Journal of Biological Chemistry. 287: 4875-82. PMID 22167194 DOI: 10.1074/Jbc.M111.318261 |
0.347 |
|
| 2012 |
Duan S, Cermak L, Pagan JK, Rossi M, Martinengo C, di Celle PF, Chapuy B, Shipp M, Chiarle R, Pagano M. FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. Nature. 481: 90-3. PMID 22113614 DOI: 10.1038/Nature10688 |
0.377 |
|
| 2012 |
Silverman JS, Skaar JR, Pagano M. SCF ubiquitin ligases in the maintenance of genome stability. Trends in Biochemical Sciences. 37: 66-73. PMID 22099186 DOI: 10.1016/J.Tibs.2011.10.004 |
0.433 |
|
| 2012 |
Chow C, Wong N, Pagano M, Lun SW, Nakayama KI, Nakayama K, Lo KW. Regulation of APC/CCdc20 activity by RASSF1A-APC/CCdc20 circuitry. Oncogene. 31: 1975-87. PMID 21874044 DOI: 10.1038/Onc.2011.372 |
0.438 |
|
| 2012 |
Yang F, Hu L, Yao Y, Yu J, Khodjakov A, Pagano M, Dai W. Abstract 2045: BubR1 is modified by sumoylation during mitotic progression Cancer Research. 72: 2045-2045. DOI: 10.1158/1538-7445.Am2012-2045 |
0.345 |
|
| 2011 |
Duan S, Skaar JR, Kuchay S, Toschi A, Kanarek N, Ben-Neriah Y, Pagano M. mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR. Molecular Cell. 44: 317-24. PMID 22017877 DOI: 10.1016/J.Molcel.2011.09.005 |
0.778 |
|
| 2011 |
Pagan J, Pagano M. FBXW5 controls centrosome number Nature Cell Biology. 13: 888-890. PMID 21808243 DOI: 10.1038/Ncb2312 |
0.348 |
|
| 2011 |
Cotto-Rios XM, Jones MJ, Busino L, Pagano M, Huang TT. APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage. The Journal of Cell Biology. 194: 177-86. PMID 21768287 DOI: 10.1083/Jcb.201101062 |
0.378 |
|
| 2011 |
Millman SE, Pagano M. MCL1 meets its end during mitotic arrest Embo Reports. 12: 384-385. PMID 21475247 DOI: 10.1038/Embor.2011.62 |
0.781 |
|
| 2011 |
Rose AE, Wang G, Hanniford D, Monni S, Tu T, Shapiro RL, Berman RS, Pavlick AC, Pagano M, Darvishian F, Mazumdar M, Hernando E, Osman I. Clinical relevance of SKP2 alterations in metastatic melanoma. Pigment Cell & Melanoma Research. 24: 197-206. PMID 20883453 DOI: 10.1111/J.1755-148X.2010.00784.X |
0.328 |
|
| 2011 |
Nguyen PL, Lin DI, Lei J, Fiorentino M, Mueller E, Weinstein MH, Pagano M, Loda M. The impact of Skp2 overexpression on recurrence-free survival following radical prostatectomy. Urologic Oncology. 29: 302-8. PMID 19450994 DOI: 10.1016/J.Urolonc.2009.03.022 |
0.323 |
|
| 2010 |
Young LM, Pagano M. Cdc25 phosphatases: differential regulation by ubiquitin-mediated proteolysis. Cell Cycle (Georgetown, Tex.). 9: 4613-4. PMID 21260951 DOI: 10.4161/Cc.9.23.13934 |
0.502 |
|
| 2010 |
D'Angiolella V, Donato V, Vijayakumar S, Saraf A, Florens L, Washburn MP, Dynlacht B, Pagano M. SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation. Nature. 466: 138-42. PMID 20596027 DOI: 10.1038/Nature09140 |
0.398 |
|
| 2010 |
Kanarek N, Horwitz E, Mayan I, Leshets M, Cojocaru G, Davis M, Tsuberi BZ, Pikarsky E, Pagano M, Ben-Neriah Y. Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion. Genes & Development. 24: 470-7. PMID 20194439 DOI: 10.1101/Gad.551610 |
0.306 |
|
| 2010 |
Ligr M, Li Y, Zou X, Daniels G, Melamed J, Peng Y, Wang W, Wang J, Ostrer H, Pagano M, Wang Z, Garabedian MJ, Lee P. Tumor suppressor function of androgen receptor coactivator ARA70alpha in prostate cancer. The American Journal of Pathology. 176: 1891-900. PMID 20167864 DOI: 10.2353/Ajpath.2010.090293 |
0.302 |
|
| 2010 |
Bashir T, Pagan JK, Busino L, Pagano M. Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization. Cell Cycle (Georgetown, Tex.). 9: 971-4. PMID 20160477 DOI: 10.4161/Cc.9.5.10914 |
0.5 |
|
| 2010 |
Peschiaroli A, Skaar JR, Pagano M, Melino G. The ubiquitin-specific protease USP47 is a novel Β-TRCP interactor regulating cell survival Oncogene. 29: 1384-1393. PMID 19966869 DOI: 10.1038/Onc.2009.430 |
0.376 |
|
| 2010 |
Bassermann F, Pagano M. Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2. Cell Death & Differentiation. 17: 78-85. PMID 19680264 DOI: 10.1038/Cdd.2009.104 |
0.352 |
|
| 2009 |
Kaldis P, Pagano M. Wnt signaling in mitosis. Developmental Cell. 17: 749-50. PMID 20059944 DOI: 10.1016/J.Devcel.2009.12.001 |
0.385 |
|
| 2009 |
Skaar JR, Richard DJ, Saraf A, Toschi A, Bolderson E, Florens L, Washburn MP, Khanna KK, Pagano M. INTS3 controls the hSSB1-mediated DNA damage response. The Journal of Cell Biology. 187: 25-32. PMID 19786574 DOI: 10.1083/Jcb.200907026 |
0.359 |
|
| 2009 |
Skaar JR, Pagano M. Control of cell growth by the SCF and APC/C ubiquitin ligases. Current Opinion in Cell Biology. 21: 816-24. PMID 19775879 DOI: 10.1016/J.Ceb.2009.08.004 |
0.353 |
|
| 2009 |
Peschiaroli A, Scialpi F, Bernassola F, Pagano M, Melino G. The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73. Oncogene. 28: 3157-66. PMID 19581926 DOI: 10.1038/Onc.2009.177 |
0.476 |
|
| 2009 |
Skaar JR, D'Angiolella V, Pagan JK, Pagano M. SnapShot: F Box Proteins II. Cell. 137: 1358, 1358.e1. PMID 19563764 DOI: 10.1016/J.Cell.2009.05.040 |
0.376 |
|
| 2009 |
Mateo F, Vidal-Laliena M, Canela N, Busino L, Martínez-Balbás M, Pagano M, Agell N, Bachs O. Degradation of cyclin A is regulated by acetylation. Oncogene. 28: 2654-2666. PMID 19483727 DOI: 10.1038/Onc.2009.127 |
0.461 |
|
| 2009 |
Hu L, Ibrahim S, Liu C, Skaar J, Pagano M, Karpatkin S. Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222. Cancer Research. 69: 3374-81. PMID 19351827 DOI: 10.1158/0008-5472.Can-08-4290 |
0.401 |
|
| 2009 |
Dehan E, Bassermann F, Guardavaccaro D, Vasiliver-Shamis G, Cohen M, Lowes KN, Dustin M, Huang DC, Taunton J, Pagano M. betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. Molecular Cell. 33: 109-16. PMID 19150432 DOI: 10.1016/J.Molcel.2008.12.020 |
0.809 |
|
| 2009 |
Ge S, Skaar JR, Pagano M. APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. Cell Cycle (Georgetown, Tex.). 8: 167-71. PMID 19098431 DOI: 10.4161/Cc.8.1.7606 |
0.663 |
|
| 2008 |
Nguyen PL, Lei J, Mueller E, Signoretti S, D'Amico AV, Lin D, Pagano M, Weinstein MH, Loda M. The association between overexpression of skp2 and the risk of recurrence following prostatectomy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 11052. PMID 27947642 DOI: 10.1200/Jco.2008.26.15_Suppl.11052 |
0.359 |
|
| 2008 |
Frescas D, Guardavaccaro D, Kuchay SM, Kato H, Poleshko A, Basrur V, Elenitoba-Johnson KS, Katz RA, Pagano M. KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state Cell Cycle. 7: 3539-3547. PMID 19001877 DOI: 10.4161/Cc.7.22.7062 |
0.772 |
|
| 2008 |
Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A. PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes & Development. 22: 2496-506. PMID 18794347 DOI: 10.1101/Gad.1676108 |
0.476 |
|
| 2008 |
Bassermann F, Frescas D, Guardavaccaro D, Busino L, Peschiaroli A, Pagano M. The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Cell. 134: 256-67. PMID 18662541 DOI: 10.1016/J.Cell.2008.05.043 |
0.762 |
|
| 2008 |
Merluzzi S, Gri G, Gattei V, Pagano M, Pucillo C. APE/Ref-1 makes fine-tuning of CD40-induced B cell proliferation. Molecular Immunology. 45: 3731-9. PMID 18617267 DOI: 10.1016/J.Molimm.2008.06.003 |
0.356 |
|
| 2008 |
Frescas D, Pagano M. Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: Tipping the scales of cancer Nature Reviews Cancer. 8: 438-449. PMID 18500245 DOI: 10.1038/Nrc2396 |
0.796 |
|
| 2008 |
Zhao X, Heng JI, Guardavaccaro D, Jiang R, Pagano M, Guillemot F, Iavarone A, Lasorella A. The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nature Cell Biology. 10: 643-53. PMID 18488021 DOI: 10.1038/Ncb1727 |
0.328 |
|
| 2008 |
Michaelson D, Abidi W, Guardavaccaro D, Zhou M, Ahearn I, Pagano M, Philips MR. Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division. The Journal of Cell Biology. 181: 485-96. PMID 18443222 DOI: 10.1083/Jcb.200801047 |
0.387 |
|
| 2008 |
Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T, Lasorella A, Iavarone A, Chang S, Hernando E, Pagano M. Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature. 452: 365-9. PMID 18354482 DOI: 10.1038/Nature06641 |
0.775 |
|
| 2008 |
Shibata R, Bassermann F, Chandra P, Resemann H, Mazumder A, Pagano M, Ibrahim S. Ritonavir Sensitizes Multiple Myeloma Cells to Bortezomib-Induced Apoptosis Blood. 112: 5194-5194. DOI: 10.1182/Blood.V112.11.5194.5194 |
0.397 |
|
| 2008 |
Chilosi M, Chiarle R, Lestani M, Menestrina F, Montagna L, Ambrosetti A, Prolla G, Pizzolo G, Doglioni C, Piva R, Pagano M, Inghirami G. Low expression of p27 and low proliferation index do not correlate in hairy cell leukaemia: p27 Expression and Proliferation Index in HCL British Journal of Haematology. 111: 263-271. DOI: 10.1111/J.1365-2141.2000.02210.X |
0.327 |
|
| 2007 |
Cardozo T, Pagano M. Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes. Bmc Biochemistry. 8: S9. PMID 18047746 DOI: 10.1186/1471-2091-8-S1-S9 |
0.41 |
|
| 2007 |
Frescas D, Guardavaccaro D, Bassermann F, Koyama-Nasu R, Pagano M. JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes. Nature. 450: 309-13. PMID 17994099 DOI: 10.1038/Nature06255 |
0.779 |
|
| 2007 |
Kitajima S, Kudo Y, Ogawa I, Tatsuka M, Kawai H, Pagano M, Takata T. Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer. Plos One. 2: e944. PMID 17895985 DOI: 10.1371/Journal.Pone.0000944 |
0.385 |
|
| 2007 |
Amador V, Ge S, Santamaría PG, Guardavaccaro D, Pagano M. APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase. Molecular Cell. 27: 462-73. PMID 17679094 DOI: 10.1016/J.Molcel.2007.06.013 |
0.684 |
|
| 2007 |
Godinho SI, Maywood ES, Shaw L, Tucci V, Barnard AR, Busino L, Pagano M, Kendall R, Quwailid MM, Romero MR, O'neill J, Chesham JE, Brooker D, Lalanne Z, Hastings MH, et al. The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science (New York, N.Y.). 316: 897-900. PMID 17463252 DOI: 10.1126/Science.1141138 |
0.328 |
|
| 2007 |
Busino L, Bassermann F, Maiolica A, Lee C, Nolan PM, Godinho SI, Draetta GF, Pagano M. SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science (New York, N.Y.). 316: 900-4. PMID 17463251 DOI: 10.1126/Science.1141194 |
0.399 |
|
| 2007 |
Xu S, Abbasian M, Patel P, Jensen-Pergakes K, Lombardo CR, Cathers BE, Xie W, Mercurio F, Pagano M, Giegel D, Cox S. Substrate recognition and ubiquitination of SCFSkp2/Cks1 ubiquitin-protein isopeptide ligase. The Journal of Biological Chemistry. 282: 15462-70. PMID 17409098 DOI: 10.1074/Jbc.M610758200 |
0.459 |
|
| 2007 |
Bassermann F, von Klitzing C, Illert AL, Münch S, Morris SW, Pagano M, Peschel C, Duyster J. Multisite phosphorylation of nuclear interaction partner of ALK (NIPA) at G2/M involves cyclin B1/Cdk1. The Journal of Biological Chemistry. 282: 15965-72. PMID 17389604 DOI: 10.1074/Jbc.M610819200 |
0.397 |
|
| 2007 |
Fielenbach N, Guardavaccaro D, Neubert K, Chan T, Li D, Feng Q, Hutter H, Pagano M, Antebi A. DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age. Developmental Cell. 12: 443-55. PMID 17336909 DOI: 10.1016/J.Devcel.2007.01.018 |
0.403 |
|
| 2007 |
Santamaría PG, Pagano M. The pRb-Cdh1-p27 autoamplifying network. Nature Cell Biology. 9: 137-8. PMID 17268477 DOI: 10.1038/Ncb0207-137 |
0.415 |
|
| 2007 |
Pagano M, Bassermann F, Peschiaroli A. Two different ubiquitin ligases control the abundance of Claspin at different phases of the cell cycle The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A154 |
0.315 |
|
| 2006 |
Dorrello NV, Peschiaroli A, Guardavaccaro D, Colburn NH, Sherman NE, Pagano M. S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science (New York, N.Y.). 314: 467-71. PMID 17053147 DOI: 10.1126/Science.1130276 |
0.441 |
|
| 2006 |
Peschiaroli A, Dorrello NV, Guardavaccaro D, Venere M, Halazonetis T, Sherman NE, Pagano M. SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Molecular Cell. 23: 319-29. PMID 16885022 DOI: 10.1016/J.Molcel.2006.06.013 |
0.349 |
|
| 2006 |
Utku Y, Dehan E, Ouerfelli O, Piano F, Zuckermann RN, Pagano M, Kirshenbaum K. A peptidomimetic siRNA transfection reagent for highly effective gene silencing. Molecular Biosystems. 2: 312-7. PMID 16880950 DOI: 10.1039/B603229J |
0.77 |
|
| 2006 |
Lasorella A, Stegmüller J, Guardavaccaro D, Liu G, Carro MS, Rothschild G, de la Torre-Ubieta L, Pagano M, Bonni A, Iavarone A. Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature. 442: 471-4. PMID 16810178 DOI: 10.1038/Nature04895 |
0.341 |
|
| 2006 |
Ji P, Goldin L, Ren H, Sun D, Guardavaccaro D, Pagano M, Zhu L. Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1. The Journal of Biological Chemistry. 281: 24058-69. PMID 16774918 DOI: 10.1074/Jbc.M603105200 |
0.443 |
|
| 2006 |
Bloom J, Peschiaroli A, Demartino G, Pagano M. Modification of Cul1 regulates its association with proteasomal subunits. Cell Division. 1: 5. PMID 16759355 DOI: 10.1186/1747-1028-1-5 |
0.795 |
|
| 2006 |
Guardavaccaro D, Pagano M. Stabilizers and Destabilizers Controlling Cell Cycle Oscillators Molecular Cell. 22: 1-4. PMID 16600864 DOI: 10.1016/J.Molcel.2006.03.017 |
0.334 |
|
| 2005 |
Bloom J, Pagano M. Experimental tests to definitively determine ubiquitylation of a substrate Methods in Enzymology. 399: 249-266. PMID 16338361 DOI: 10.1016/S0076-6879(05)99017-4 |
0.788 |
|
| 2005 |
Hao B, Zheng N, Schulman BA, Wu G, Miller JJ, Pagano M, Pavletich NP. Structural basis of the Cks1-dependent recognition of p27 Kip1 by the SCF Skp2 ubiquitin ligase Molecular Cell. 20: 9-19. PMID 16209941 DOI: 10.1016/J.Molcel.2005.09.003 |
0.444 |
|
| 2005 |
Block K, Appikonda S, Lin HR, Bloom J, Pagano M, Yew PR. The acidic tail domain of human Cdc34 is required for p27Kip1 ubiquitination and complementation of a cdc34 temperature sensitive yeast strain. Cell Cycle (Georgetown, Tex.). 4: 1421-7. PMID 16123592 DOI: 10.4161/Cc.4.10.2054 |
0.773 |
|
| 2005 |
Benmaamar R, Pagano M. Involvement of the SCF complex in the control of Cdh1 degradation in S-phase Cell Cycle. 4: 1230-1232. PMID 16123585 DOI: 10.4161/Cc.4.9.2048 |
0.36 |
|
| 2005 |
Bashir T, Pagano M. Cdk1: The dominant sibling of Cdk2 Nature Cell Biology. 7: 779-781. PMID 16056272 DOI: 10.1038/Ncb0805-779 |
0.415 |
|
| 2005 |
Dehan E, Pagano M. Skp2, the FoxO1 hunter Cancer Cell. 7: 209-210. PMID 15766658 DOI: 10.1016/J.Ccr.2005.02.014 |
0.803 |
|
| 2004 |
Kitajima S, Kudo Y, Ogawa I, Bashir T, Kitagawa M, Miyauchi M, Pagano M, Takata T. Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation. The American Journal of Pathology. 165: 2147-55. PMID 15579456 DOI: 10.1016/S0002-9440(10)63264-6 |
0.439 |
|
| 2004 |
Baumeister W, Bachmair A, Chau V, Cohen R, Coffino P, Demartino G, Deshaies R, Dohmen J, Emr S, Finley D, Hampton R, Hill C, Hochstrasser M, Huber R, Jackson P, ... ... Pagano M, et al. Varshavsky's contributions. Science (New York, N.Y.). 306: 1290-2. PMID 15550643 DOI: 10.1126/Science.306.5700.1290 |
0.407 |
|
| 2004 |
Yamasaki L, Pagano M. Cell cycle, proteolysis and cancer. Current Opinion in Cell Biology. 16: 623-8. PMID 15530772 DOI: 10.1016/J.Ceb.2004.08.005 |
0.434 |
|
| 2004 |
Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW. Systematic analysis and nomenclature of mammalian F-box proteins. Genes & Development. 18: 2573-80. PMID 15520277 DOI: 10.1101/Gad.1255304 |
0.334 |
|
| 2004 |
Ji P, Jiang H, Rekhtman K, Bloom J, Ichetovkin M, Pagano M, Zhu L. An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant. Molecular Cell. 16: 47-58. PMID 15469821 DOI: 10.1016/J.Molcel.2004.09.029 |
0.804 |
|
| 2004 |
Cardozo T, Pagano M. The SCF ubiquitin ligase: insights into a molecular machine. Nature Reviews. Molecular Cell Biology. 5: 739-51. PMID 15340381 DOI: 10.1038/Nrm1471 |
0.381 |
|
| 2004 |
Kudo Y, Guardavaccaro D, Santamaria PG, Koyama-Nasu R, Latres E, Bronson R, Yamasaki L, Pagano M. Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis. Molecular and Cellular Biology. 24: 8184-94. PMID 15340078 DOI: 10.1128/Mcb.24.18.8184-8194.2004 |
0.365 |
|
| 2004 |
Pagano M, Jackson PK. Wagging the dogma; tissue-specific cell cycle control in the mouse embryo. Cell. 118: 535-8. PMID 15339658 DOI: 10.1016/J.Cell.2004.08.013 |
0.404 |
|
| 2004 |
Bashir T, Pagano M. Don't skip the G1 phase: How APC/CCdh1 keeps SCF Skp2 in check Cell Cycle. 3: 850-852. PMID 15190201 DOI: 10.4161/Cc.3.7.977 |
0.303 |
|
| 2004 |
Bernassola F, Salomoni P, Oberst A, Di Como CJ, Pagano M, Melino G, Pandolfi PP. Ubiquitin-dependent degradation of p73 is inhibited by PML. The Journal of Experimental Medicine. 199: 1545-57. PMID 15184504 DOI: 10.1084/Jem.20031943 |
0.443 |
|
| 2004 |
Pagano M. Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis Molecular Cell. 14: 414-416. PMID 15149588 DOI: 10.1016/S1097-2765(04)00268-0 |
0.394 |
|
| 2004 |
Moshe Y, Boulaire J, Pagano M, Hershko A. Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome. Proceedings of the National Academy of Sciences of the United States of America. 101: 7937-42. PMID 15148369 DOI: 10.1073/Pnas.0402442101 |
0.468 |
|
| 2004 |
Shapira M, Ben-Izhak O, Bishara B, Futerman B, Minkov I, Krausz MM, Pagano M, Hershko DD. Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma. Cancer. 100: 1615-1621. PMID 15073847 DOI: 10.1002/Cncr.20172 |
0.387 |
|
| 2004 |
Guardavaccaro D, Pagano M. Oncogenic aberrations of cullin-dependent ubiquitin ligases Oncogene. 23: 2037-2049. PMID 15021891 DOI: 10.1038/Sj.Onc.1207413 |
0.408 |
|
| 2004 |
Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature. 428: 190-3. PMID 15014502 DOI: 10.1038/Nature02330 |
0.489 |
|
| 2004 |
Bloom J, Pagano M. To be or not to be... ubiquitinated? Cell Cycle. 3: 138-140. PMID 14712075 |
0.805 |
|
| 2004 |
Bloom J, Pagano M. To Be or Not to Be...Ubiquitinated? Cell Cycle. 3: 136-138. DOI: 10.4161/Cc.3.2.659 |
0.814 |
|
| 2003 |
Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, Dorrello NV, Hershko A, Pagano M, Draetta GF. Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature. 426: 87-91. PMID 14603323 DOI: 10.1038/Nature02082 |
0.378 |
|
| 2003 |
Pagano M, Benmaamar R. When protein destruction runs amok, malignancy is on the loose Cancer Cell. 4: 251-256. PMID 14585352 DOI: 10.1016/S1535-6108(03)00243-5 |
0.419 |
|
| 2003 |
Bloom J, Amador V, Bartolini F, DeMartino G, Pagano M. Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation. Cell. 115: 71-82. PMID 14532004 DOI: 10.1016/S0092-8674(03)00755-4 |
0.788 |
|
| 2003 |
Bornstein G, Bloom J, Sitry-Shevah D, Nakayama K, Pagano M, Hershko A. Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase. The Journal of Biological Chemistry. 278: 25752-7. PMID 12730199 DOI: 10.1074/Jbc.M301774200 |
0.82 |
|
| 2003 |
Bashir T, Pagano M. Aberrant ubiquitin-mediated proteolysis of cell cycle regulatory proteins and oncogenesis Advances in Cancer Research. 88: 101-144. PMID 12665054 DOI: 10.1016/S0065-230X(03)88305-7 |
0.483 |
|
| 2003 |
Bloom J, Pagano M. Deregulated degradation of the cdk inhibitor p27 and malignant transformation Seminars in Cancer Biology. 13: 41-47. PMID 12507555 DOI: 10.1016/S1044-579X(02)00098-6 |
0.8 |
|
| 2003 |
McAllister SS, Becker-Hapak M, Pintucci G, Pagano M, Dowdy SF. Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions. Molecular and Cellular Biology. 23: 216-28. PMID 12482975 DOI: 10.1128/Mcb.23.1.216-228.2003 |
0.464 |
|
| 2003 |
Piva R, Liu J, Chiarle R, Podda A, Pagano M, Inghirami G. In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation. Molecular and Cellular Biology. 22: 8375-87. PMID 12417738 DOI: 10.1128/Mcb.22.23.8375-8387.2002 |
0.309 |
|
| 2002 |
Bloom J, Pagano M. Butyrolactone: more than a kinase inhibitor? Cell Cycle (Georgetown, Tex.). 1: 117-118. PMID 12429918 DOI: 10.4161/Cc.1.2.114 |
0.753 |
|
| 2002 |
Donzelli M, Squatrito M, Ganoth D, Hershko A, Pagano M, Draetta GF. Dual mode of degradation of Cdc25 A phosphatase. The Embo Journal. 21: 4875-84. PMID 12234927 DOI: 10.1093/Emboj/Cdf491 |
0.5 |
|
| 2002 |
Sitry D, Seeliger MA, Ko TK, Ganoth D, Breward SE, Itzhaki LS, Pagano M, Hershko A. Three different binding sites of Cks1 are required for p27-ubiquitin ligation. The Journal of Biological Chemistry. 277: 42233-40. PMID 12140288 DOI: 10.1074/Jbc.M205254200 |
0.389 |
|
| 2002 |
Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex Nature. 416: 703-709. PMID 11961546 DOI: 10.1038/416703A |
0.39 |
|
| 2002 |
Chiarle R, Fan Y, Piva R, Boggino H, Skolnik J, Novero D, Palestro G, Wolf-Peeters CD, Chilosi M, Pagano M, Inghirami G. S-Phase Kinase-Associated Protein 2 Expression in Non-Hodgkin's Lymphoma Inversely Correlates with p27 Expression and Defines Cells in S Phase American Journal of Pathology. 160: 1457-1466. PMID 11943729 DOI: 10.1016/S0002-9440(10)62571-0 |
0.432 |
|
| 2002 |
Rodier G, Montagnoli A, Di Marcotullio L, Coulombe P, Draetta GF, Pagano M, Meloche S. p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis. The Embo Journal. 20: 6672-82. PMID 11726503 DOI: 10.1093/Emboj/20.23.6672 |
0.428 |
|
| 2002 |
Cheng H, Cenciarelli C, Shao Z, Vidal M, Parks WP, Pagano M, Cheng-Mayer C. Human T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70. Current Biology : Cb. 11: 1771-5. PMID 11719219 DOI: 10.1016/S0960-9822(01)00540-1 |
0.413 |
|
| 2002 |
Bloom J, Pagano M. Butyrolactone: More than a Kinase Inhibitor? Cell Cycle. 1: 108-109. DOI: 10.4161/Cc.1.2.110 |
0.773 |
|
| 2001 |
DeSalle LM, Latres E, Lin D, Graner E, Montagnoli A, Baker RT, Pagano M, Loda M. The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein. Oncogene. 20: 5538-42. PMID 11571652 DOI: 10.1038/Sj.Onc.1204824 |
0.785 |
|
| 2001 |
Carrano AC, Pagano M. Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression Journal of Cell Biology. 153: 1381-1389. PMID 11425869 DOI: 10.1083/Jcb.153.7.1381 |
0.811 |
|
| 2001 |
Spiegelman VS, Stavropoulos P, Latres E, Pagano M, Ronai Z, Slaga TJ, Fuchs SY. Induction of β-Transducin Repeat-containing Protein by JNK Signaling and Its Role in the Activation of NF-κB Journal of Biological Chemistry. 276: 27152-27158. PMID 11375388 DOI: 10.1074/Jbc.M100031200 |
0.379 |
|
| 2001 |
Hershko D, Bornstein G, Ben-Izhak O, Carrano A, Pagano M, Krausz MM, Hershko A. Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas. Cancer. 91: 1745-51. PMID 11335900 DOI: 10.1002/1097-0142(20010501)91:9<1745::Aid-Cncr1193>3.0.Co;2-H |
0.791 |
|
| 2001 |
Ganoth D, Bornstein G, Ko TK, Larsen B, Tyers M, Pagano M, Hershko A. The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nature Cell Biology. 3: 321-4. PMID 11231585 DOI: 10.1038/35060126 |
0.507 |
|
| 2001 |
Latres E, Chiarle R, Schulman BA, Pavletich NP, Pellicer A, Inghirami G, Pagano M. Role of the F-box protein Skp2 in lymphomagenesis Proceedings of the National Academy of Sciences of the United States of America. 98: 2515-2520. PMID 11226270 DOI: 10.1073/Pnas.041475098 |
0.408 |
|
| 2001 |
DeSalle LM, Pagano M. Regulation of the G1 to S transition by the ubiquitin pathway Febs Letters. 490: 179-189. PMID 11223033 DOI: 10.1016/S0014-5793(01)02121-4 |
0.805 |
|
| 2000 |
Chiarle R, Pagano M, Inghirami G. The cyclin dependent kinase inhibitor p27 and its prognostic role in breast cancer. Breast Cancer Research : Bcr. 3: 91-4. PMID 11250752 DOI: 10.1186/Bcr277 |
0.359 |
|
| 2000 |
Kipreos ET, Pagano M. The F-box protein family Genome Biology. 1. PMID 11178263 DOI: 10.1186/Gb-2000-1-5-Reviews3002 |
0.375 |
|
| 2000 |
Schulman BA, Carrano AC, Jeffrey PD, Bowen Z, Kinnucan ERE, Finnin MS, Elledge SJ, Harper JW, Pagano M, Pavletich NP. Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex Nature. 408: 381-386. PMID 11099048 DOI: 10.1038/35042620 |
0.78 |
|
| 2000 |
Chilosi M, Chiarle R, Lestani M, Menestrina F, Montagna L, Ambrosetti A, Prolla G, Pizzolo G, Doglioni C, Piva R, Pagano M, Inghirami G. Low expression of p27 and low proliferation index do not correlate in hairy cell leukaemia British Journal of Haematology. 111: 263-271. PMID 11091210 DOI: 10.1046/J.1365-2141.2000.02210.X |
0.407 |
|
| 2000 |
Cangi MG, Cukor B, Soung P, Signoretti S, Moreira G, Ranashinge M, Cady B, Pagano M, Loda M. Role of the Cdc25A phosphatase in human breast cancer. Journal of Clinical Investigation. 106: 753-761. PMID 10995786 DOI: 10.1172/Jci9174 |
0.321 |
|
| 2000 |
Spiegelman VS, Slaga TJ, Pagano M, Minamoto T, Ronai Z, Fuchs SY. Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor. Molecular Cell. 5: 877-82. PMID 10882123 DOI: 10.1016/S1097-2765(00)80327-5 |
0.301 |
|
| 2000 |
Chiaur DS, Murthy S, Cenciarelli C, Parks W, Loda M, Inghirami G, Demetrick D, Pagano M. Five human genes encoding F-box proteins: chromosome mapping and analysis in human tumors Cytogenetic and Genome Research. 88: 255-258. PMID 10828603 DOI: 10.1159/000015532 |
0.324 |
|
| 2000 |
Slingerland J, Pagano M. Regulation of the Cdk inhibitor p27 and its deregulation in cancer Journal of Cellular Physiology. 183: 10-17. PMID 10699961 DOI: 10.1002/(Sici)1097-4652(200004)183:1<10::Aid-Jcp2>3.0.Co;2-I |
0.416 |
|
| 2000 |
Chiarle R, Budel LM, Skolnik J, Frizzera G, Chilosi M, Corato A, Pizzolo G, Magidson J, Montagnoli A, Pagano M, Maes B, Wolf-Peeters CD, Inghirami G. Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma. Blood. 95: 619-626. DOI: 10.1182/Blood.V95.2.619 |
0.409 |
|
| 1999 |
Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nature Cell Biology. 1: 193-9. PMID 10559916 DOI: 10.1038/12013 |
0.816 |
|
| 1999 |
Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M. Identification of a family of human F-box proteins Current Biology. 9: 1177-1179. PMID 10531035 DOI: 10.1016/S0960-9822(00)80020-2 |
0.379 |
|
| 1999 |
Gonen H, Bercovich B, Orian A, Carrano A, Takizawa C, Yamanaka K, Pagano M, Iwai K, Ciechanover A. Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IκBα Journal of Biological Chemistry. 274: 14823-14830. PMID 10329681 DOI: 10.1074/Jbc.274.21.14823 |
0.8 |
|
| 1999 |
Montagnoli A, Fiore F, Eytan E, Carrano AC, Draetta GF, Hershko A, Pagano M. Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. Genes & Development. 13: 1181-9. PMID 10323868 DOI: 10.1101/Gad.13.9.1181 |
0.807 |
|
| 1999 |
Latres E, Chiaur DS, Pagano M. The human F box protein β-Trcp associates with the Cul1/Skp1 complex and regulates the stability of β-catenin Oncogene. 18: 849-854. PMID 10023660 DOI: 10.1038/Sj.Onc.1202653 |
0.304 |
|
| 1999 |
Pagano M. Protein degradation is not chaos Trends in Biochemical Sciences. 24: 40-41. DOI: 10.1016/S0968-0004(98)01307-3 |
0.365 |
|
| 1998 |
Thomas GV, Szigeti K, Murphy M, Draetta G, Pagano M, Loda M. Down-Regulation of p27 Is Associated with Development of Colorectal Adenocarcinoma Metastases American Journal of Pathology. 153: 681-687. PMID 9736017 DOI: 10.1016/S0002-9440(10)65610-6 |
0.394 |
|
| 1998 |
Slingerland J, Pagano M. Regulation of the cell cycle by the ubiquitin pathway Results and Problems in Cell Differentiation. 22: 133-147. PMID 9670322 DOI: 10.1007/978-3-540-69686-5_6 |
0.412 |
|
| 1998 |
Lu Z, Liu D, Hornia A, Devonish W, Pagano M, Foster DA. Activation of protein kinase C triggers its ubiquitination and degradation. Molecular and Cellular Biology. 18: 839-45. PMID 9447980 DOI: 10.1128/Mcb.18.2.839 |
0.432 |
|
| 1998 |
Zhang Y, Wang Z, Liu DX, Pagano M, Ravid K. Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes Journal of Biological Chemistry. 273: 1387-1392. PMID 9430673 DOI: 10.1074/Jbc.273.3.1387 |
0.408 |
|
| 1997 |
Pagano M. Cell cycle regulation by the ubiquitin pathway Faseb Journal. 11: 1067-1075. PMID 9367342 DOI: 10.1096/Fasebj.11.13.9367342 |
0.467 |
|
| 1997 |
Brown JP, Pagano M. Mechanism of p53 degradation Biochimica Et Biophysica Acta - Reviews On Cancer. 1332. PMID 9141469 DOI: 10.1016/S0304-419X(96)00048-0 |
0.357 |
|
| 1997 |
Alessandrini A, Chiaur D, Pagano M. Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation Leukemia. 11: 342-345. PMID 9067571 DOI: 10.1038/Sj.Leu.2400581 |
0.51 |
|
| 1997 |
Millard SS, Yan JS, Nguyen H, Pagano M, Kiyokawa H, Koff A. Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. The Journal of Biological Chemistry. 272: 7093-8. PMID 9054402 DOI: 10.1074/Jbc.272.11.7093 |
0.436 |
|
| 1997 |
Loda M, Cukor B, Tam SW, Lavin P, Fiorentinc M, Draetta GF, Jessup JM, Pagano M. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas Nature Medicine. 3: 231-234. PMID 9018245 DOI: 10.1038/Nm0297-231 |
0.428 |
|
| 1996 |
DelSal G, Loda M, Pagano M. Cell cycle and cancer: critical events at the G1 restriction point. Critical Reviews in Oncogenesis. 7: 127-142. PMID 9109501 DOI: 10.1615/Critrevoncog.V7.I1-2.80 |
0.43 |
|
| 1996 |
Chen J, Peters R, Saha P, Lee P, Theodoras A, Pagano M, Wagner G, Dutta A. A 39 Amino Acid Fragment of the Cell Cycle Regulator p21 Is Sufficient to Bind PCNA and Partially Inhibit DNA Replication in vivo Nucleic Acids Research. 24: 1727-1733. PMID 8649992 DOI: 10.1093/Nar/24.9.1727 |
0.384 |
|
| 1996 |
Grinstein E, Weinert I, Droese B, Pagano M, Royer HD. Cell cycle regulation of nuclear factor p92 DNA-binding activity by novel phase-specific inhibitors Journal of Biological Chemistry. 271: 9215-9222. PMID 8621580 DOI: 10.1074/Jbc.271.16.9215 |
0.448 |
|
| 1996 |
Castoria G, Migliaccio A, Bilancio A, Pagano M, Abbondanza C, Auricchio F. A 67 kDa non-hormone binding estradiol receptor is present in human mammary cancers. International Journal of Cancer. 65: 574-583. PMID 8598306 DOI: 10.1002/(Sici)1097-0215(19960301)65:5<574::Aid-Ijc4>3.0.Co;2-# |
0.311 |
|
| 1996 |
Draetta G, Pagano M. Chapter 25. Cell Cycle Control and Cancer Annual Reports in Medicinal Chemistry. 31: 241-248. DOI: 10.1016/S0065-7743(08)60464-9 |
0.488 |
|
| 1995 |
Ohtsubo M, Theodoras AM, Schumacher J, Roberts JM, Pagano M. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Molecular and Cellular Biology. 15: 2612-24. PMID 7739542 DOI: 10.1128/Mcb.15.5.2612 |
0.375 |
|
| 1995 |
Rolfe M, Beer-Romero P, Glass S, Eckstein J, Berdo I, Theodoras A, Pagano M, Draetta G. Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP). Proceedings of the National Academy of Sciences of the United States of America. 92: 3264-3268. PMID 7724550 DOI: 10.1073/Pnas.92.8.3264 |
0.433 |
|
| 1995 |
Pagano M, Tam SW, Theodoras AM, Beer-Romero P, Del Sal G, Chau V, Yew PR, Draetta GF, Rolfe M. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science (New York, N.Y.). 269: 682-5. PMID 7624798 DOI: 10.1126/Science.7624798 |
0.508 |
|
| 1995 |
Roussel MF, Theodoras AM, Pagano M, Sherr CJ. Rescue of defective mitogenic signaling by D-type cyclins Proceedings of the National Academy of Sciences of the United States of America. 92: 6837-6841. PMID 7624328 DOI: 10.1073/Pnas.92.15.6837 |
0.349 |
|
| 1995 |
Steiner P, Philipp A, Lukas J, Godden-Kent D, Pagano M, Mittnacht S, Bartek J, Eilers M. Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes. The Embo Journal. 14: 4814-4826. DOI: 10.1002/J.1460-2075.1995.Tb00163.X |
0.414 |
|
| 1994 |
Spitkovsky D, Steiner P, Lukas J, Lees E, Pagano M, Schulze A, Joswig S, Picard D, Tommasino M, Eilers M, Jansen-Dürr P. Modulation of cyclin gene expression by adenovirus E1A in a cell line with E1A-dependent conditional proliferation Journal of Virology. 68: 2206-2214. PMID 8139005 DOI: 10.1128/Jvi.68.4.2206-2214.1994 |
0.365 |
|
| 1994 |
Pagano M, Theodoras AM, Tam SW, Draetta GF. Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes & Development. 8: 1627-1639. PMID 7958844 DOI: 10.1101/Gad.8.14.1627 |
0.331 |
|
| 1993 |
Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G. Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes & Development. 7: 812-821. PMID 8491378 DOI: 10.1101/Gad.7.5.812 |
0.362 |
|
| 1993 |
Pagano M, Pepperkok R, Lukas J, Baldin V, Ansorge W, Bartek J, Draetta G. Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts Journal of Cell Biology. 121: 101-111. PMID 8458862 DOI: 10.1083/Jcb.121.1.101 |
0.438 |
|
| 1993 |
Jansen-Dürr P, Meichle A, Steiner P, Pagano M, Finke K, Botz J, Wessbecher J, Draetta G, Eilers M. Differential modulation of cyclin gene expression by MYC. Proceedings of the National Academy of Sciences of the United States of America. 90: 3685-9. PMID 8386381 DOI: 10.1073/Pnas.90.8.3685 |
0.363 |
|
| 1992 |
Clarke PR, Leiss D, Pagano M, Karsenti E. Cyclin A- and cyclin B-dependent protein kinases are regulated by different mechanisms in Xenopus egg extracts. The Embo Journal. 11: 1751-61. PMID 1316271 DOI: 10.1002/J.1460-2075.1992.Tb05227.X |
0.45 |
|
| 1992 |
Pagano M, Pepperkok R, Verde F, Ansorge W, Draetta G. Cyclin A is required at two points in the human cell cycle. The Embo Journal. 11: 961-71. PMID 1312467 DOI: 10.1002/J.1460-2075.1992.Tb05135.X |
0.441 |
|
| 1992 |
Pagano M, Draetta G, Jansen-Dürr P. Association of cdk2 kinase with the transcription factor E2F during S phase Science. 255: 1144-1147. PMID 1312258 DOI: 10.1126/Science.1312258 |
0.441 |
|
| 1991 |
Pagano M, Draetta G. Cyclin A, cell cycle control and oncogenesis Progress in Growth Factor Research. 3: 267-277. PMID 1839823 DOI: 10.1016/0955-2235(91)90004-N |
0.425 |
|
| 1988 |
Auricchio F, Migliaccio A, Castoria G, Rotondi A, Domenico MD, Pagano M, Nola E. Phosphorylation of Estradiol Receptor on Tyrosine and Interaction of Estradiol and Glucocorticoid Receptors with Antiphosphotyrosine Antibodies Advances in Experimental Medicine and Biology. 231: 519-540. PMID 2458018 DOI: 10.1007/978-1-4684-9042-8_44 |
0.37 |
|
| 1986 |
Auricchio F, Migliaccio A, Castoria G, Rotondi A, Domenico MD, Pagano M. Activation-inactivation of hormone binding sites of the oestradiol-17β receptor is a multiregulated process Journal of Steroid Biochemistry. 24: 39-43. PMID 3009987 DOI: 10.1016/0022-4731(86)90029-4 |
0.312 |
|
| Show low-probability matches. |